epigenetically_modified_region [SO_0001720]
A biological DNA region implicated in epigenomic changes caused by mechanisms other than changes in the underlying DNA sequence. This includes, nucleosomal histone post-translational modifications, nucleosome depletion to render DNA accessible and post-replicational base modifications such as cytosine modification. Moved from is_a biological_region (SO:0001411) to is_a regulatory_region (SO:0005836) on 11 Feb 2021. GREEKC members pointed out that this would be a more appropriate location. See GitHub Issue #530. 11 Feb 2021 updated definition along with addition of epigenomically_modified_region (SO:0002332). Epigenetically modified region is now not inherited while epigenomically modified region is not annotated as inherited. See GitHub Issue #532 and issue #534.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/SO_0001720",
"symbol": "",
"types": [
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],
"short_form": "SO_0001720",
"label": "epigenetically_modified_region"
},
"description": [
"A biological DNA region implicated in epigenomic changes caused by mechanisms other than changes in the underlying DNA sequence. This includes, nucleosomal histone post-translational modifications, nucleosome depletion to render DNA accessible and post-replicational base modifications such as cytosine modification."
],
"comment": [
"Moved from is_a biological_region (SO:0001411) to is_a regulatory_region (SO:0005836) on 11 Feb 2021. GREEKC members pointed out that this would be a more appropriate location. See GitHub Issue #530. 11 Feb 2021 updated definition along with addition of epigenomically_modified_region (SO:0002332). Epigenetically modified region is now not inherited while epigenomically modified region is not annotated as inherited. See GitHub Issue #532 and issue #534."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
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"short_form": "SO_0005836",
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"label": "has_quality",
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"iri": "http://purl.obolibrary.org/obo/SO_0000133",
"types": [
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"short_form": "SO_0000133",
"label": "epigenetically_modified"
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}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "epigenetically modified region",
"type": ""
},
"pub": {
"core": {
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"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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