ecdysteroid 25-hydroxylase activity [GO_0035302]

Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods. Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22,25-trideoxyecdysone (3-beta,5-beta-ketodiol) to 2,22-dideoxyecdysone (3-beta,5-beta-ketotriol).
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Open ecdysteroid 25-hydroxylase activity in VFB

Term Information

  • ID: GO_0035302
  • Name: ecdysteroid 25-hydroxylase activity
  • Definition: Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.
  • Synonyms:
  • Type:
  • Comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22,25-trideoxyecdysone (3-beta,5-beta-ketodiol) to 2,22-dideoxyecdysone (3-beta,5-beta-ketotriol).

VFB Term Json

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            "short_form": "GO_0035302",
            "unique_facets": [
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            "label": "ecdysteroid 25-hydroxylase activity"
        },
        "description": [
            "Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods."
        ],
        "comment": [
            "Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22,25-trideoxyecdysone (3-beta,5-beta-ketodiol) to 2,22-dideoxyecdysone (3-beta,5-beta-ketotriol)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008395",
            "types": [
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                "has_subClass"
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            "short_form": "GO_0008395",
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            ],
            "label": "Defective CYP11B2 does not oxidise CORST"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
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                "short_form": "Unattributed",
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