tumor necrosis factor-mediated signaling pathway [GO_0033209]

The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
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Open tumor necrosis factor-mediated signaling pathway in VFB

Term Information

  • ID: GO_0033209
  • Name: tumor necrosis factor-mediated signaling pathway
  • Definition: The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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            "symbol": "",
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            "short_form": "GO_0033209",
            "unique_facets": [
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            "label": "tumor necrosis factor-mediated signaling pathway"
        },
        "description": [
            "The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019221",
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            ],
            "short_form": "GO_0019221",
            "unique_facets": [
                "Class"
            ],
            "label": "cytokine-mediated signaling pathway"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0071356",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0071356",
                "unique_facets": [
                    "Class"
                ],
                "label": "cellular response to tumor necrosis factor"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "tumor necrosis factor alpha-mediated signaling pathway",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "adipocytokine signaling pathway",
                "type": ""
            },
            "pub": {
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        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "TNF-alpha-mediated signaling pathway",
                "type": ""
            },
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    ],
    "def_pubs": []
}