neurotrophin signaling pathway [GO_0038179]
The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons. There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0038179",
"symbol": "",
"types": [
"Entity",
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],
"short_form": "GO_0038179",
"label": "neurotrophin signaling pathway"
},
"description": [
"The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons."
],
"comment": [
"There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0007166",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0007166",
"label": "cell surface receptor signaling pathway"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
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"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0071363",
"types": [
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],
"short_form": "GO_0071363",
"label": "cellular response to growth factor stimulus"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
]
}
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