iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane [GO_0140318]
Directly binding to a specific protein and delivering it to a specific cellular location. Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane in VFB
VFB Term Json
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"label": "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane"
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],
"comment": [
"Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation."
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