G protein activity [GO_0003925]

A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).

Open G protein activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003925",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003925",
            "label": "G protein activity"
        },
        "description": [
            "A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0003924",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003924",
            "label": "ARHGAP35 stimulates RHOA GTPase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0098772",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0098772",
            "label": "molecular function regulator"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "small monomeric G protein activity",
                "type": ""
            },
            "pub": {
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                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "signaling G protein activity",
                "type": ""
            },
            "pub": {
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                    "short_form": "Unattributed",
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                "FlyBase": "",
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            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "Ras superfamily protein",
                "type": ""
            },
            "pub": {
                "core": {
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            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "large G-protein activity",
                "type": ""
            },
            "pub": {
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "small G-protein",
                "type": ""
            },
            "pub": {
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        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "small GTPase activity",
                "type": ""
            },
            "pub": {
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                },
                "FlyBase": "",
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            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "small monomeric GTPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
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                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "heterotrimeric G-protein GTPase activity",
                "type": ""
            },
            "pub": {
                "core": {
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            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "small GTPase",
                "type": ""
            },
            "pub": {
                "core": {
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            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "large G-protein GTPase activity",
                "type": ""
            },
            "pub": {
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        }
    ],
    "def_pubs": []
}