oxidative DNA demethylase activity [GO_0035516]
Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen oxidative DNA demethylase activity in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0035516",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0035516",
"label": "oxidative DNA demethylase activity"
},
"description": [
"Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016706",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0016706",
"label": "2-oxoglutarate-dependent dioxygenase activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0035514",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0035514",
"label": "DNA demethylase activity"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "N3-methylcytosine demethylase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"Individual",
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],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "N1-methyladenine demethylase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "1-ethyladenine demethylase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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