NAD+ nucleosidase activity, cyclic ADP-ribose generating [GO_0061809]
Catalysis of the reaction: NAD+ + H2O = ADP-D-ribose + nicotinamide + H+, in a two step reaction: first an ADP-ribosyl cyclase reaction to synthesise cyclic ADP-ribose, followed by a cyclic ADP-ribose hydrolase reaction to generate (linear) ADP-ribose.
NAD+ nucleosidase activity, cyclic ADP-ribose generating
ID: GO_0061809
Class
Catalysis of the reaction: NAD+ + H2O = ADP-D-ribose + nicotinamide + H+, in a two step reaction: first an ADP-ribosyl cyclase reaction to synthesise cyclic ADP-ribose, followed by a cyclic ADP-ribose hydrolase reaction to generate (linear) ADP-ribose.
Open in VFB 3D Browser →Classification
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| NAD hydrolase | narrow synonym | |
| nicotinamide adenine dinucleotide nucleosidase | narrow synonym | |
| NAD(+) nucleosidase | narrow synonym | |
| NADase | narrow synonym | |
| ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | exact synonym |
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