methyltransferase cap1 activity [GO_0004483]
Catalysis of the reaction: a 5’-end (N(7)-methyl 5’-triphosphoguanosine)-ribonucleoside in mRNA or snRNA + S-adenosyl-L-methionine = a 5’-end (N(7)-methyl 5’-triphosphoguanosine)-(2’-O-methyl-ribonucleoside) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the first transcribed nucleotide of mRNAs and snRNAs.
methyltransferase cap1 activity
ID: GO_0004483
Class
Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the first transcribed nucleotide of mRNAs and snRNAs.
Open in VFB 3D Browser →Classification
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| mRNA (adenosine-2’-O-)-methyltransferase activity | related synonym | 2.1.1.57 |
| messenger ribonucleate nucleoside 2’-methyltransferase activity | related synonym | 2.1.1.57 |
| mRNA (nucleoside-2’-O-)-methyltransferase activity | related synonym | 2.1.1.57 |
| S-adenosyl-L-methionine:mRNA (nucleoside-2’-O-)-methyltransferase activity | related synonym | 2.1.1.57 |
| messenger RNA (nucleoside-2’-)-methyltransferase activity | related synonym | 2.1.1.57 |
References
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