hydroxymethylglutaryl-CoA synthase activity [GO_0004421]

Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+.
Tags:

hydroxymethylglutaryl-CoA synthase activity

ID: GO_0004421

Class

Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+.

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Classification

Alternative Names

Synonym Scope Reference
beta-hydroxy-beta-methylglutaryl-CoA synthase activity related synonym 2.3.3.10
hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity related synonym 2.3.3.10
HMG-CoA synthase activity related synonym 2.3.3.10
(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating) related synonym 2.3.3.10
3-hydroxy-3-methylglutaryl CoA synthetase activity related synonym 2.3.3.10
acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) related synonym 2.3.3.10
3-hydroxy-3-methylglutaryl-coenzyme A synthase activity related synonym 2.3.3.10
3-hydroxy-3-methylglutaryl coenzyme A synthase activity related synonym 2.3.3.10
3-hydroxy-3-methylglutaryl coenzyme A synthetase activity related synonym 2.3.3.10
(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity related synonym 2.3.3.10
3-hydroxy-3-methylglutaryl-CoA synthase activity related synonym 2.3.3.10
acetoacetyl coenzyme A transacetase activity related synonym 2.3.3.10
hydroxymethylglutaryl coenzyme A-condensing enzyme related synonym 2.3.3.10
hydroxymethylglutaryl coenzyme A synthase activity related synonym 2.3.3.10

References