aconitate hydratase activity [GO_0003994]

Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.

aconitate hydratase activity

ID: GO_0003994

Class

Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.

Open in VFB 3D Browser →

Classification

Alternative Names

Synonym Scope Reference
cis-aconitase activity related synonym 4.2.1.3
citrate(isocitrate) hydro-lyase activity related synonym 4.2.1.3
citrate(isocitrate) hydro-lyase (cis-aconitate-forming) related synonym 4.2.1.3
citrate hydro-lyase activity broad synonym 4.2.1.3
aconitase activity exact synonym

References