presumptive hindbrain [UBERON_0007277]
The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, ‘rhombencephalosynapsis’ is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/UBERON_0007277",
"symbol": "",
"types": [
"Entity",
"Anatomy",
"Class"
],
"short_form": "UBERON_0007277",
"label": "presumptive hindbrain"
},
"description": [
"The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0006598",
"types": [
"Entity",
"Anatomy",
"Class"
],
"short_form": "UBERON_0006598",
"label": "presumptive structure"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0006238",
"types": [
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"Anatomy",
"Class"
],
"short_form": "UBERON_0006238",
"label": "future brain"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002387",
"label": "has potential to develop into",
"type": "has_potential_to_develop_into"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0002028",
"types": [
"Entity",
"Anatomy",
"Class"
],
"short_form": "UBERON_0002028",
"label": "hindbrain"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002254",
"label": "has developmental contribution from",
"type": "has_developmental_contribution_from"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0003852",
"types": [
"Entity",
"Anatomy",
"Class"
],
"short_form": "UBERON_0003852",
"label": "rhombencephalon neural crest"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002202",
"label": "develops from",
"type": "develops_from"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0003076",
"types": [
"Entity",
"Anatomy",
"Class"
],
"short_form": "UBERON_0003076",
"label": "posterior neural tube"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "embryonic rhombencephalon",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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