adult renal stem cell [FBbt_00110862]

Stem cell of the adult Malpighian tubule (Singh et al., 2007). These are small cells occupying a basal position and are only found in the lower tubule and ureter (stem cell zone) (Singh et al., 2007; Wang and Spradling, 2020). They are usually quiescent, but can generate replacement principal cells in response to injury (Wang and Spradling, 2020). Within the stem cell zone, they are more numerous than type I (principal) cells (Wang and Spradling, 2020). Can be identified by expression of escargot (Singh et al., 2007; Wang and Spradling, 2020).
Tags:

Open adult renal stem cell in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110862",
            "symbol": "",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class"
            ],
            "short_form": "FBbt_00110862",
            "label": "adult renal stem cell"
        },
        "description": [
            "Stem cell of the adult Malpighian tubule (Singh et al., 2007). These are small cells occupying a basal position and are only found in the lower tubule and ureter (stem cell zone) (Singh et al., 2007; Wang and Spradling, 2020). They are usually quiescent, but can generate replacement principal cells in response to injury (Wang and Spradling, 2020). Within the stem cell zone, they are more numerous than type I (principal) cells (Wang and Spradling, 2020)."
        ],
        "comment": [
            "Can be identified by expression of escargot (Singh et al., 2007; Wang and Spradling, 2020)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110861",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class"
            ],
            "short_form": "FBbt_00110861",
            "label": "Malpighian tubule tiny cell"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00005733",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class"
            ],
            "short_form": "FBbt_00005733",
            "label": "adult specialized Malpighian tubule cell"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00007344",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class"
            ],
            "short_form": "FBbt_00007344",
            "label": "somatic stem cell"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00049469",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class"
                ],
                "short_form": "FBbt_00049469",
                "label": "adult stem cell zone of Malpighian tubule"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003004",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class"
                ],
                "short_form": "FBbt_00003004",
                "label": "adult"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002292",
                "label": "expresses",
                "type": "expresses"
            },
            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgn0001981",
                "types": [
                    "Entity",
                    "Class",
                    "Feature"
                ],
                "short_form": "FBgn0001981",
                "label": "esg"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult RSC",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0245230",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0245230",
                    "label": "Wang and Spradling, 2020, eLife 9: e54096"
                },
                "FlyBase": "",
                "PubMed": "32175841",
                "DOI": "10.7554/eLife.54096"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult RNSC",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0202697",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0202697",
                    "label": "Singh et al., 2007, Cell Stem Cell 1(2): 191--203"
                },
                "FlyBase": "",
                "PubMed": "18371350",
                "DOI": "10.1016/j.stem.2007.07.003"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult Malpighian tubule tiny cell",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0202697",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0202697",
                    "label": "Singh et al., 2007, Cell Stem Cell 1(2): 191--203"
                },
                "FlyBase": "",
                "PubMed": "18371350",
                "DOI": "10.1016/j.stem.2007.07.003"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0202697",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0202697",
                "label": "Singh et al., 2007, Cell Stem Cell 1(2): 191--203"
            },
            "FlyBase": "",
            "PubMed": "18371350",
            "DOI": "10.1016/j.stem.2007.07.003"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0245230",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0245230",
                "label": "Wang and Spradling, 2020, eLife 9: e54096"
            },
            "FlyBase": "",
            "PubMed": "32175841",
            "DOI": "10.7554/eLife.54096"
        }
    ]
}