FlyBase Controlled Vocabulary (FBcv)
A miscellaneous ontology of terms used for curation in FlyBase, including the DPO.
Tag: FBcv
Drosophila Phenotype Ontology (DPO)
An ontology for the description of Drosophila melanogaster phenotypes.
Categories:
10x sequencing [FBcv_0009008]
A method that uses the Chromium platform from 10x Genomics to prepare and sequence a cDNA library.
abnormal adult locomotory behavior [FBcv_0007529]
Any abnormality in adult locomotory behavior (GO:0008344), which is defined as ‘Locomotory behavior in a fully developed and mature organism.’.
abnormal adult walking behavior [FBcv_0007527]
Any abnormality in adult walking behavior (GO:0007628), which is defined as ‘The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.’.
abnormal aging [FBcv_0000384]
Phenotype that is any abnormality in aging (GO:0007568). ‘aging’ is defined as: ‘A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).’
abnormal anesthesia-resistant memory [FBcv_0007500]
Phenotype that is any abnormality in anesthesia-resistant memory (GO:0007615). ‘anesthesia-resistant memory’ is defined as: ‘The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.’
abnormal auditory perception [FBcv_0000407]
Phenotype that is any abnormality in sensory perception of sound (GO:0007605). ‘sensory perception of sound’ is defined as: ‘The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.’
abnormal axis specification [FBcv_0000686]
Phenotype that is any abnormality in axis specification (GO:0009798). ‘axis specification’ is defined as: ‘The establishment, maintenance and elaboration of a pattern along a line or around a point.’ This phenotypic class does not encompass planar polarity.
abnormal behavior [FBcv_0000387]
Phenotype that is any abnormality in behavior (GO:0007610). ‘behavior’ is defined as: ‘The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.’
abnormal body color [FBcv_0000356]
A phenotype that is any abnormality in body color compared to wild-type.
abnormal body size [FBcv_0000665]
Phenotype that is an abnormality in body size compared to wild-type animals raised under the same conditions as the animals exhibiting the phenotype.
abnormal body weight [FBcv_0007504]
Phenotype that is any abnormality in body weight compared to identically raised wild-type controls.
abnormal cell adhesion [FBcv_0000668]
Phenotype that is any abnormality in cell adhesion (GO:0007155). ‘cell adhesion’ is defined as: ‘The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.’
abnormal cell cycle [FBcv_0000671]
Phenotype that is any abnormality in cell cycle (GO:0007049). ‘cell cycle’ is defined as: ‘The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.’
abnormal cell death [FBcv_0000424]
Phenotype that is a change in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type. This may be due to effects on the regulation of cell death (GO:0010941) or in cell death (GO:0008219) pathways themselves.
abnormal cell growth [FBcv_0000427]
Phenotype that is any abnormality in cell growth (GO:0016049). ‘cell growth’ is defined as: ‘The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.’ Note that defects in cell size are not necessarily the result of defects in cell growth. A change in the rate of cell division in the absence of any change in cell growth rate can result in smaller or larger cells.
abnormal cell migration [FBcv_0000716]
Phenotype that is any abnormality in cell migration (GO:0016477). ‘cell migration’ is defined as: ‘The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.’
abnormal cell number [FBcv_0000709]
Phenotype that is an increase or decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by defects in cell growth - there may be a greater or lesser number of cells in an otherwise normal volume of tissue.
abnormal cell polarity [FBcv_0000430]
Phenotype that is any abnormality in the asymmetric distribution of components within a cell. For example an epithelial cell is ‘cell polarity defective’ if it lacks the normal asymmetric distribution of proteins or cell components such as junctions or villi along its apical-basal axis.
abnormal cell shape [FBcv_0000429]
Phenotype that is any abnormality in the shape (PATO:0000052) of some cell compared to wild-type.
abnormal cell size [FBcv_0000428]
Phenotype that is any abnormality in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type.
abnormal chemosensitive behavior [FBcv_0000403]
Phenotype that is any abnormality in chemosensory behavior (GO:0007635). ‘chemosensory behavior’ is defined as: ‘Behavior that is dependent upon the sensation of chemicals.’.’
abnormal circadian behavior [FBcv_0000679]
Phenotype that is any abnormality in circadian behavior (GO:0048512). ‘circadian behavior’ is defined as: ‘The specific behavior of an organism that recurs with a regularity of approximately 24 hours.’
abnormal circadian rhythm [FBcv_0000394]
Phenotype that is any abnormality in circadian rhythm (GO:0007623). ‘circadian rhythm’ is defined as: ‘Any biological process in an organism that recurs with a regularity of approximately 24 hours.’
abnormal cold stress response [FBcv_0000684]
Phenotype that is any abnormality in response to cold (GO:0009409). ‘response to cold’ is defined as: ‘Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.’
abnormal copulation [FBcv_0006000]
Phenotype that is any abnormality in copulation (GO:0007620). ‘copulation’ is defined as: ‘The act of sexual union between male and female, involving the transfer of sperm.’
abnormal courtship behavior [FBcv_0000399]
Phenotype that is any abnormality in courtship behavior (GO:0007619). ‘courtship behavior’ is defined as: ‘The behavior of an organism for the purpose of attracting sexual partners.’
abnormal cytokinesis [FBcv_0000433]
Phenotype that is any abnormality in cytokinesis (GO:0000910). ‘cytokinesis’ is defined as: ‘The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.’
abnormal developmental rate [FBcv_0000450]
Phenotype that is a change in the rate of some developmental process (GO:0032502) taking place prior to mature adulthood (defined as adult stage A3), compared to wild-type. Note, developmental processes include stages in development of the whole animal (e.g.- larval development) as well as specific sub-processes, such as dorsal closure. A more complete formalization would require a clause specifying stage. It might be possible to do this in OWL using the same system as we are using for lethal phase.
abnormal diapause [FBcv_0000706]
Phenotype that is any abnormality in entry into diapause (GO:0055115). ’entry into diapause’ is defined as: ‘The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.’
abnormal DNA repair [FBcv_0000423]
Phenotype that is any abnormality in DNA repair (GO:0006281). ‘DNA repair’ is defined as: ‘The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.’
abnormal dorsal/ventral axis specification [FBcv_0000324]
Phenotype that is any abnormality in dorsal/ventral axis specification (GO:0009950). ‘dorsal/ventral axis specification’ is defined as: ‘The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.’
abnormal eclosion [FBcv_0000670]
Phenotype that is any abnormality in eclosion (GO:0007562). ’eclosion’ is defined as: ‘The emergence of an adult insect from a pupa case.’
abnormal eclosion rhythm [FBcv_0000396]
Phenotype that is any abnormality in eclosion rhythm (GO:0008062). ’eclosion rhythm’ is defined as: ‘The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.’
abnormal endomitotic cell cycle [FBcv_0000672]
Phenotype that is any abnormality in endomitotic cell cycle (GO:0007113). ’endomitotic cell cycle’ is defined as: ‘A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.’
abnormal eye color [FBcv_0000355]
Phenotype that is any abnormality in eye color compared to wild-type.
abnormal feeding behavior [FBcv_0000419]
Phenotype that is any abnormality in feeding behavior (GO:0007631). ‘feeding behavior’ is defined as: ‘Behavior associated with the intake of food.’
abnormal flight [FBcv_0000417]
Phenotype that is any abnormality in flight (GO:0060361). ‘flight’ is defined as: ‘Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.’ This term is agnostic as to the causes of defects in flight. An animal’s flight may be defective for mechanical, behavioral or sensory reasons.
abnormal gravitaxis [FBcv_0000388]
Phenotype that is a change in the strong tendency, seen in wild-type Drosophila melanogaster, to climb - a behavior otherwise known as negative gravitaxis (GO:0048060 ; movement away from the source of gravity). Note, this term should not be used when flies have climbing defects purely as a consequence of locomotion defects, use ’locomotor behavior defective’ instead.
abnormal grooming behavior [FBcv_0000420]
Phenotype that is any abnormality in grooming behavior (GO:0007625). ‘grooming behavior’ is defined as: ‘The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.’
abnormal hatching behavior [FBcv_0000669]
Phenotype that is any abnormality in hatching behavior (GO:0035187). ‘hatching behavior’ is defined as: ‘The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.’
abnormal heat stress response [FBcv_0000410]
Phenotype that is any abnormality in response to heat (GO:0009408). ‘response to heat’ is defined as: ‘Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.’
abnormal immune response [FBcv_0000448]
Phenotype that is any abnormality in immune response (GO:0006955). ‘immune response’ is defined as: ‘Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.’
abnormal jump response [FBcv_0000720]
Phenotype that is any abnormality or in or absence of a jump response (GO:0007630). The jump response in Drosophila is a reflex escape response that can be triggered by a number of signals including odor and light. Standard assays are commonly used to test odor and light induced jump response.
abnormal jumping [FBcv_0000415]
Phenotype that is a reduced ability to jump or a reduced jump response. This may be due to neurological or muscular defects.
abnormal larval locomotory behavior [FBcv_0007528]
Any abnormality in larval locomotory behavior (GO:0008345), which is defined as ‘Locomotory behavior in a larval (immature) organism.’.
abnormal learning [FBcv_0000397]
Phenotype that is any abnormality in learning (GO:0007612). ’learning’ is defined as: ‘Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.’
abnormal locomotor behavior [FBcv_0000414]
Phenotype that is any abnormality in locomotory behavior (GO:0007626). ’locomotory behavior’ is defined as: ‘The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism’s internal state and external conditions.’
abnormal locomotor rhythm [FBcv_0000395]
Phenotype that is any abnormality in locomotor rhythm (GO:0045475). ’locomotor rhythm’ is defined as: ‘The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.’
abnormal long-term memory [FBcv_0007503]
Phenotype that is any abnormality in long-term memory (GO:0007616). ’long-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.’
abnormal mating [FBcv_0000400]
Phenotype that is any abnormality in mating (GO:0007618). ‘mating’ is defined as: ‘The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.’
abnormal mating behavior [FBcv_0000721]
Phenotype that is any abnormality in mating behavior (GO:0007617). ‘mating behavior’ is defined as: ‘The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.’
abnormal mating rhythm [FBcv_0000401]
Phenotype that is any abnormality in circadian mating behavior (GO:0035648). ‘circadian mating behavior’ is defined as: ‘The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.’
abnormal medium-term memory [FBcv_0007502]
Phenotype that is any abnormality in medium-term memory (GO:0072375). ‘medium-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).’
abnormal meiotic cell cycle [FBcv_0000431]
Phenotype that is any abnormality in meiotic cell cycle (GO:0051321). ‘meiotic cell cycle’ is defined as: ‘Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.’
abnormal memory [FBcv_0000398]
Phenotype that is any abnormality in memory (GO:0007613). ‘memory’ is defined as: ‘The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).’
abnormal mitotic cell cycle [FBcv_0000432]
Phenotype that is any abnormality in mitotic cell cycle (GO:0000278). ‘mitotic cell cycle’ is defined as: ‘Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.’
abnormal neuroanatomy [FBcv_0000435]
Phenotype that is any abnormality in the anatomy of the nervous system (FBbt:00005093). ’nervous system’ is defined as: ‘All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.’
abnormal neurophysiology [FBcv_0000434]
Phenotype that is any abnormality in the electrophysiological properties of some class of neurons, muscles or other anatomical structure of the nervous system. Examples of these phenotypes at the neuron class level include defects in spontaneous or evoked excitatory junction potential. Examples at a more gross anatomical level include abnormal retinal electrophysiology (e.g.- measured by an electroretinogram).
abnormal optomotor response [FBcv_0000412]
Phenotype that is any abnormality in optomotor response: a motor response during flight or walking that serves to stabilize both image formation on the retina and locomotor course.
abnormal osmotic stress response [FBcv_0000409]
Phenotype that is any abnormality in response to osmotic stress (GO:0006970). ‘response to osmotic stress’ is defined as: ‘Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.’
abnormal oviposition [FBcv_0006004]
Phenotype that is any abnormality in oviposition (GO:0007620). ‘oviposition’ is defined as: ‘The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.’. This term should only be used to report defects specifically in oviposition, as opposed to an overall loss of fertility. If a difference in “oviposition rate” is measured by authors as a proxy for sterility/fertility, it would be better to use the terms “sterile”, “semi-sterile”, or “semi-fertile”, as appropriate.
abnormal oxidative stress response [FBcv_0000725]
Phenotype that is any abnormality in response to oxidative stress (GO:0006979). ‘response to oxidative stress’ is defined as: ‘Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.’
abnormal pain response [FBcv_0000393]
Phenotype that is any abnormality in response to pain (GO:0048265). ‘response to pain’ is defined as: ‘Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.’
abnormal phototaxis [FBcv_0000413]
Phenotype that is any abnormality in phototaxis (GO:0042331). ‘phototaxis’ is defined as: ‘The directed movement of a motile cell or organism in response to light.’
abnormal planar polarity [FBcv_0000449]
Phenotype that is any abnormality in establishment of planar polarity (GO:0001736). ’establishment of planar polarity’ is defined as: ‘Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.’ For apical-basal polarity phenotypes of epithelia, the appropriate term is ‘cell polarity defective’.
abnormal proboscis extension reflex [FBcv_0000680]
Phenotype that is any abnormality in proboscis extension reflex (GO:0007637). ‘proboscis extension reflex’ is defined as: ‘The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.’
abnormal reproductive diapause [FBcv_0000707]
Phenotype that is any abnormality in entry into reproductive diapause (GO:0055116). ’entry into reproductive diapause’ is defined as: ‘The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.’
abnormal sensory perception [FBcv_0000681]
Phenotype that is any abnormality in sensory perception (GO:0007600). ‘sensory perception’ is defined as: ‘The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.’
abnormal sex-determination [FBcv_0000436]
Phenotype that is any abnormality in sex determination (GO:0007530). ‘sex determination’ is defined as: ‘Any process that establishes and transmits the specification of sexual status of an individual organism.’
abnormal short-term memory [FBcv_0007501]
Phenotype that is any abnormality in short-term memory (GO:0007614). ‘short-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.’
abnormal size [FBcv_0000357]
A phenotype that is any abnormality in the size of the whole body or some body part compared to wild-type.
abnormal sleep [FBcv_0000705]
Phenotype that is any abnormality in sleep (GO:0030431). ‘sleep’ is defined as: ‘Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.’
abnormal smell perception [FBcv_0000404]
Phenotype that is any abnormality in sensory perception of smell (GO:0007608). ‘sensory perception of smell’ is defined as: ‘The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism’s ambient medium by chemoreceptors. This is a neurological process.’
abnormal song [FBcv_0000402]
Phenotype that is any abnormality in male courtship behavior, veined wing generated song production (GO:0045433). This is defined as ‘The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.’
abnormal starvation stress response [FBcv_0000708]
Phenotype that is any abnormality in response to starvation (GO:0042594). ‘response to starvation’ is defined as: ‘Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.’
abnormal stress response [FBcv_0000408]
Phenotype that is any abnormality in response to stress (GO:0006950). ‘response to stress’ is defined as: ‘Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).’
abnormal tarsal response [FBcv_0000406]
Phenotype that is any abnormality in or absense of proboscis extension reflex in response to a sugar stimulus via taste sensilla on the tarsus.
abnormal taste perception [FBcv_0000405]
Phenotype that is any abnormality in sensory perception of taste (GO:0050909). ‘sensory perception of taste’ is defined as: ‘The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.’
abnormal temperature response [FBcv_0000683]
Phenotype that is any abnormality in response to temperature stimulus (GO:0009266). ‘response to temperature stimulus’ is defined as: ‘Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.’
abnormal thermotaxis [FBcv_0000002]
Phenotype that is any abnormality in thermotaxis (GO:0043052). ’thermotaxis’ is defined as: ‘The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.’
abnormal touch perception [FBcv_0000682]
Phenotype that is any abnormality in sensory perception of touch (GO:0050975). ‘sensory perception of touch’ is defined as: ‘The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).’
abnormal touch response [FBcv_0000421]
Phenotype that is any abnormality in or loss of a stereotypical behavioral response to touch. This phenotype is commonly assayed by scoring larval avoidance responses following stroking of the thoracic segments (see Kernan et al., 1994). On its own, this is not sufficient evidence for an abnormality in sensory perception of touch, as motor defects can also cause this phenotype.
abnormal visual behavior [FBcv_0000411]
Phenotype that is any abnormality in visual behavior (GO:0007632). ‘visual behavior’ is defined as: ‘The behavior of an organism in response to a visual stimulus.’
abnormal visual perception [FBcv_0004000]
Phenotype that is any abnormality in sensory perception of light stimulus (GO:0050953). ‘sensory perception of light stimulus’ is defined as: ‘The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.’
abnormal wound healing [FBcv_0000451]
Phenotype that is any abnormality in wound healing (GO:0042060). ‘wound healing’ is defined as: ‘The series of events that restore integrity to a damaged tissue, following an injury.’
analysis [FBcv_0003108]
A result that is produced from the detailed examination of data to come to some conclusion.
assay [FBcv_0003025]
Quantitative or qualitative assessment of biological source material to measure some attribute.
assay attribute [FBcv_0003175]
Some characteristic of an assay pertaining to the methods involved in processing the biological source material or generating the raw output data of the assay.
assay method [FBcv_0003208]
A method used to characterize the biological molecules isolated from a biosample.
assay type [FBcv_0003050]
The type of assay as characterized by its data content.
atrophy [FBcv_0000719]
Phenotype that is a decrease in size of an initially normally sized organ or tissue due to wasting away of cells.
auxotroph [FBcv_0000383]
A phenotype that is the inability to synthesize some organic compound that can be synthesized by wild-type animals, and that is required for normal growth and/or development.
bang sensitive [FBcv_0000391]
A phenotype exhibited following mechanical shock and consisting of a brief period of intense, uncoordinated motor activity (legs and wings flailing, abdomen coiling) followed by a prolonged period of paralysis.
biosample [FBcv_0003024]
Biological source material characterized by an experiment.
cell clustering analysis [FBcv_0009002]
A result that groups individual cells into populations sharing a similar transcriptional profile.
cell lethal [FBcv_0000353]
A phenotype that is a failure of mutant cells to survive. Typically, this phenotype is assayed in clones of cells.
chemical resistant [FBcv_0000439]
Phenotype that is a decreased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase ’toxic effects’ here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death.
chemical sensitive [FBcv_0000440]
Phenotype that is an increased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase ’toxic effects’ here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death.
dataset attribute [FBcv_0003121]
A descriptor that describes some aspect of a dataset.
dataset data type [FBcv_0003028]
The data type content of a dataset.
dataset descriptor [FBcv_0003021]
Term that describes a dataset.
dataset entity type [FBcv_0003022]
Term that specifies the dataset component type.
decreased anesthesia-resistant memory [FBcv_0007524]
Phenotype that is a decrease in the efficacy of anesthesia-resistant memory (GO:0007615) relative to controls. ‘anesthesia-resistant memory’ is defined as: ‘The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.’ This will usually be measured as a decreased magnitude/rate of a behavioral output associated with anesthesia-resistant memory formation.
decreased body size [FBcv_0000358]
Phenotype that is a decrease in body size compared to identically raised wild-type controls.
decreased body weight [FBcv_0007506]
Phenotype that is a decrease in body weight compared to identically raised wild-type controls.
decreased cell death [FBcv_0000426]
Phenotype that is a decrease in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
decreased cell growth [FBcv_0000718]
Phenotype that is an decrease in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
decreased cell number [FBcv_0000359]
Phenotype that is a decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth - there may be fewer cells in an otherwise normal volume of tissue.
decreased cell size [FBcv_0000360]
Phenotype that is a decrease in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth of a tissue - there may be more cells in an otherwise normal volume of tissue. Note that defects in cell size are not necessarily the result of defects in cell growth. A change in the rate of cell division in the absence of any change in cell growth rate can result in smaller or larger cells.
decreased fecundity [FBcv_0006002]
Phenotype that is a decrease in the number of gametes produced.
decreased feeding behavior [FBcv_0007516]
Phenotype that is a decrease in the total amount or frequency of feeding behavior (GO:0007631) over a given time interval, compared to wild-type. ‘feeding behavior’ is defined as: ‘Behavior associated with the intake of food.’
decreased long-term memory [FBcv_0007522]
Phenotype that is a decrease in the efficacy of long-term memory (GO:0007616) relative to controls. ’long-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.’ This will usually be measured as a decreased magnitude/rate of a behavioral output associated with long-term memory formation.
decreased medium-term memory [FBcv_0007526]
Phenotype that is a decrease in the efficacy of medium-term memory (GO:0072375) relative to controls. ‘medium-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).’ This will usually be measured as a decreased magnitude/rate of a behavioral output associated with medium-term memory formation.
decreased memory [FBcv_0007518]
Phenotype that is a decrease in the efficacy of memory (GO:0007613) relative to controls. ‘memory’ is defined as: ‘The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).’ This will usually be measured as a decreased magnitude/rate of a behavioral output associated with memory formation.
decreased occurrence of cell division [FBcv_0006006]
A phenotype that is a decreased occurrence of cell division (GO:0051301). ‘cell division’ is defined as ‘The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.’.
decreased rate of cell adhesion [FBcv_0007512]
Phenotype that is a decrease in the rate of cell adhesion (GO:0007155). ‘cell adhesion’ is defined as: ‘The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.’
decreased rate of phototaxis [FBcv_0007510]
Phenotype that is a decrease in the rate of phototaxis (GO:0042331). ‘phototaxis’ is defined as: ‘The directed movement of a motile cell or organism in response to light.’
decreased short-term memory [FBcv_0007520]
Phenotype that is a decrease in the efficacy of short-term memory (GO:0007614) relative to controls. ‘short-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.’ This will usually be measured as a decreased magnitude/rate of a behavioral output associated with short-term memory formation.
decreased size [FBcv_0007508]
A phenotype that is a decrease in the size of the whole body or some body part compared to wild-type.
decreased sleep [FBcv_0007514]
Phenotype that is a decrease in the total amount or frequency of sleep (GO:0030431) over a given time interval, compared to wild-type. ‘sleep’ is defined as: ‘Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.’
delayed aging [FBcv_0000791]
A phenotype in which the aging process (GO:0007568) is slower than in wild-type.
descriptor [FBcv_0000013]
Term that describes an allele, balancer, group or publication.
electrophoretic variant [FBcv_0000438]
Phenotype that is a difference in electrophoretic migration of a gene product compared to wild-type.
embryonic/larval segmentation phenotype [FBcv_0000698]
A phenotype that is a disruption in the wild-type pattern of segments or parasegments of the embryo or larva. Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
enhancer of variegation [FBcv_0000379]
Genotype g1 is an enhancer of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is greater than that caused by g2 alone. Typically, g2 is a chromosomal aberration or an insertion.
even pair-rule phenotype [FBcv_0000700]
Embryonic/larval segmentation phenotype that is the complete or partial loss of even segments. Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
female fertile [FBcv_0000377]
A phenotype that is the ability of females to produce fertilized eggs as a result of mating. Note - this term should not be used with the qualifier ‘partially’ - use female semi-sterile or female semi-fertile instead.
female semi-fertile [FBcv_0000007]
A phenotype that is a reduction in the ability of females to produce fertilized eggs as a result of mating, but only to > 50% of wild-type.
female semi-sterile [FBcv_0000367]
A phenotype that is a reduction in the ability of females to produce fertilized eggs as a result of mating to below 50% of wild-type.
female sterile [FBcv_0000366]
A phenotype that is the inability of females to produce fertilized eggs as a result of mating. The cause of sterility may be physical or behavioral. Note: this term should not be used with the qualifier ‘partially’ - use semi-sterile or semi-fertile instead.
female sterile germline-dependent [FBcv_0000368]
A phenotype of female sterility due to defects in the female germline.
female sterile soma-dependent [FBcv_0000369]
A phenotype of female sterility due to defects in somatic cells of the ovary (FBbt:00006030), or of the products of these cells (such as eggshell).
fertile [FBcv_0000374]
A phenotype that is the ability to produce fertilized eggs as a result of mating. Note, this term should not be used with the qualifier ‘partially’. Use semi-sterile or semi-fertile instead.
flightless [FBcv_0000418]
Phenotype that is the absence of flight (GO:0060361). ‘flight’ is defined as: ‘Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.’ This term is agnostic as to the causes of flightlessness. An animal may be flightless for mechanical or behavioral reasons.
FlyBase CV [FBcv_0000000]
FlyBase miscellaneous controlled vocabulary term.
gap phenotype [FBcv_0000703]
Embryonic/larval segmentation phenotype that is the complete loss of a contiguous stretch of 2 or more segments. Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
grandchildless [FBcv_0000378]
A phenotype in which all offspring are sterile. Typically, this is due to maternal effect sterility resulting from defects in pole cell development.
homeotic [FBcv_0000316]
Phenotype that is the partial or full transformation of one or more segments (FBbt:00000003) or segmental appendages from one identity to another. For example, in antennapedia an antenna is partially or fully transformed into a leg.
hyperactive [FBcv_0000392]
A phenotype consisting of increased frequency of multicellular organismal movement (GO:0050879) compared to wild-type.
hyperplasia [FBcv_0000444]
Phenotype that is an increase in size of a tissue or organ due to increased numbers of cells, where the affected tissue or organ maintains its normal form.
hypoactive [FBcv_0000390]
A phenotype consisting of decreased frequency of multicellular organismal movement (GO:0050879) compared to wild-type.
hypoplasia [FBcv_0000724]
Phenotype that is a reduction in size of an organ or tissue compared to wild-type due to reduced numbers of cells being produced during its development or growth. This term should not be used where an organ or tissue is reduced in size due to the wasting away of existing cells.
increased anesthesia-resistant memory [FBcv_0007523]
Phenotype that is an increase in the efficacy of anesthesia-resistant memory (GO:0007615) relative to controls. ‘anesthesia-resistant memory’ is defined as: ‘The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.’ This will usually be measured as an increased magnitude/rate of a behavioral output associated with anesthesia-resistant memory formation.
increased body size [FBcv_0000361]
Phenotype that is an increase in body size compared to identically raised wild-type controls.
increased body weight [FBcv_0007505]
Phenotype that is an increase in body weight compared to identically raised wild-type controls.
increased cell death [FBcv_0000425]
Phenotype that is an increase in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
increased cell growth [FBcv_0000717]
Phenotype that is an increase in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type.
increased cell number [FBcv_0000362]
Phenotype that is an increase in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by overgrowth of a tissue - there may be more cells in an otherwise normal volume of tissue. It is not necessarily due to an increase in cell growth -it may be the result of an increase in the division rate at normal growth rates. It may not even be due to an increase in the cell division rate - a reduced rate of cell death while the division rate is normal could also achieve it.
increased cell size [FBcv_0000363]
Phenotype that is an increase in the size of cells compared to wild-type. May be due to an increase in the cell growth rate or to a reduced rate of cell division along with a normal rate of cell growth.
increased fecundity [FBcv_0006001]
Phenotype that is an increase in the number of gametes produced.
increased feeding behavior [FBcv_0007515]
Phenotype that is an increase in the total amount or frequency of feeding behavior (GO:0007631) over a given time interval, compared to wild-type. ‘feeding behavior’ is defined as: ‘Behavior associated with the intake of food.’
increased long-term memory [FBcv_0007521]
Phenotype that is an increase in the efficacy of long-term memory (GO:0007616) relative to controls. ’long-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.’ This will usually be measured as an increased magnitude/rate of a behavioral output associated with long-term memory formation.
increased medium-term memory [FBcv_0007525]
Phenotype that is an increase in the efficacy of medium-term memory (GO:0072375) relative to controls. ‘medium-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).’ This will usually be measured as an increased magnitude/rate of a behavioral output associated with medium-term memory formation.
increased memory [FBcv_0007517]
Phenotype that is an increase in the efficacy of memory (GO:0007613) relative to controls. ‘memory’ is defined as: ‘The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).’ This will usually be measured as an increased magnitude/rate of a behavioral output associated with memory formation.
increased mortality [FBcv_0002004]
A phenotype that is an increase in the rate of death in a population at any stage of life (during development or adulthood), over the rate seen in a wild type control population.
increased mortality during development [FBcv_0002019]
A phenotype of a population that is the death of a significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
increased occurrence of cell division [FBcv_0006005]
A phenotype that is an increased occurrence of cell division (GO:0051301). ‘cell division’ is defined as ‘The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.’.
increased rate of cell adhesion [FBcv_0007511]
Phenotype that is an increase in the rate of cell adhesion (GO:0007155). ‘cell adhesion’ is defined as: ‘The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.’
increased rate of phototaxis [FBcv_0007509]
Phenotype that is an increase in the rate of phototaxis (GO:0042331). ‘phototaxis’ is defined as: ‘The directed movement of a motile cell or organism in response to light.’
increased short-term memory [FBcv_0007519]
Phenotype that is an increase in the efficacy of short-term memory (GO:0007614) relative to controls. ‘short-term memory’ is defined as: ‘The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.’ This will usually be measured as an increased magnitude/rate of a behavioral output associated with short-term memory formation.
increased size [FBcv_0007507]
A phenotype that is an increase in the size of the whole body or some body part compared to wild-type.
increased sleep [FBcv_0007513]
Phenotype that is an increase in the total amount or frequency of sleep (GO:0030431) over a given time interval, compared to wild-type. ‘sleep’ is defined as: ‘Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.’
jumpless [FBcv_0000713]
Phenotype that is a inability to jump. This may be due to neurological or muscular defects.
lethal [FBcv_0000351]
A phenotype of a population that is the death of all animals in that population at some stage or stages prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012). Note on usage: lethal is appropriate in cases where escaper adults are very rare. The lethal phase prior to becoming a mature adult may be further specified using children terms which specify stage.
lethal - all die before end of first instar larval stage [FBcv_0002001]
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the first instar larval stage.
lethal - all die before end of larval stage [FBcv_0002002]
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the larval stage. As the larval stage and third instar larval stage have the same end, there is no need for a separate term for ’lethal - all die before end of third instar larval stage'.
lethal - all die before end of P-stage [FBcv_0002000]
A phenotype of a population that is the death of all animals in that population at some stage or stages prior to eclosion from the pupal case (the end of the P-stage). As the P-Stage and the ‘pharate adult stage’ have the same end, there is no need for a separate term for ’lethal - all die before end of pharate adult stage.
lethal - all die before end of prepupal stage [FBcv_0002026]
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the prepupal stage.
lethal - all die before end of pupal stage [FBcv_0002027]
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the pupal stage.
lethal - all die before end of second instar larval stage [FBcv_0002003]
A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the second instar larval stage.
lethal - all die during embryonic stage [FBcv_0002033]
A phenotype of a population that is the death of all animals in that population during the embryonic stage.
lethal - all die during first instar larval stage [FBcv_0002006]
A phenotype of a population that is the death of all animals in that population during the first instar larval stage.
lethal - all die during immature adult stage [FBcv_0002042]
A phenotype of a population that is the death of all animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
lethal - all die during larval stage [FBcv_0002007]
A phenotype of a population that is the death of all animals in that population during the larval stage.
lethal - all die during P-stage [FBcv_0002005]
A phenotype of a population that is the death of all animals in that population during the P-stage.
lethal - all die during pharate adult stage [FBcv_0002025]
A phenotype of a population that is the death of all animals in that population during the pharate adult stage.
lethal - all die during prepupal stage [FBcv_0002031]
A phenotype of a population that is the death of all animals in that population during the prepupal stage.
lethal - all die during pupal stage [FBcv_0002030]
A phenotype of a population that is the death of all animals in that population during the pupal stage.
lethal - all die during second instar larval stage [FBcv_0002008]
A phenotype of a population that is the death of all animals in that population during the second instar larval stage.
lethal - all die during third instar larval stage [FBcv_0002009]
A phenotype of a population that is the death of all animals in that population during the third instar larval stage.
long lived [FBcv_0000386]
Phenotype that is a longer adult life-span than wild-type.
majority die during embryonic stage [FBcv_0002037]
A phenotype of a population that is the death of the majority of animals in that population during the embryonic stage. This term is agnostic about whether any survive to adulthood.
majority die during first instar larval stage [FBcv_0002011]
A phenotype of a population that is the death of the majority of animals in that population during the first instar larval stage.
majority die during immature adult stage [FBcv_0002050]
A phenotype of a population that is the death of the majority of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
majority die during larval stage [FBcv_0002012]
A phenotype of a population that is the death of the majority of animals in that population during the larval stage.
majority die during P-stage [FBcv_0002010]
A phenotype of a population that is the death of the majority of animals in that population during the P-stage.
majority die during pharate adult stage [FBcv_0002036]
A phenotype of a population that is the death of the majority of animals in that population during the pharate adult stage.
majority die during prepupal stage [FBcv_0002035]
A phenotype of a population that is the death of the majority of animals in that population during the prepupal stage.
majority die during pupal stage [FBcv_0002034]
A phenotype of a population that is the death of the majority of animals in that population during the pupal stage.
majority die during second instar larval stage [FBcv_0002013]
A phenotype of a population that is the death of the majority of animals in that population during the second instar larval stage.
majority die during third instar larval stage [FBcv_0002014]
A phenotype of a population that is the death of the majority of animals in that population during the third instar larval stage.
male fertile [FBcv_0000376]
A phenotype that is the ability of males to produce fertilized eggs as a result of mating. Note - this term should not be used with the qualifier ‘partially’ - use male semi-sterile or male semi-fertile instead.
male semi-fertile [FBcv_0000006]
A phenotype that is a reduction in the ability of males to produce fertilized eggs as a result of mating, but only to > 50% of wild-type.
male semi-sterile [FBcv_0000371]
A phenotype that is a reduction in the ability of males to produce fertilized eggs as a result of mating to below 50% of wild-type.
male sterile [FBcv_0000370]
A phenotype that is the inability of males to produce fertilized eggs as a result of mating. The cause of sterility may be physical or behavioral. Note - this term should not be used with the qualifier ‘partially’ - use semi-sterile or semi-fertile instead.
male sterile germline-dependent [FBcv_0000372]
A phenotype of male sterility due to defects in the male germline.
male sterile soma-dependent [FBcv_0000373]
A phenotype of male sterility due to defects in somatic cells of the testis (FBbt:00006031) or of the products of these cells.
melanotic mass phenotype [FBcv_0000446]
Phenotype characterized by the formation of lumps of melanotic tissue inside the body in the absence of foreign bodies. Melanotic capsules are formed around foreign bodies in wild-type animals as part of the immune response, for example as a protection against parasitoid wasps. Some, but not all melanotic mass phenotypes involve ectopic activation of this immune response. While melanotic masses are commonly referred to as melanotic tumors in the historical literature, this is a misnomer as they are rarely neoplastic.
melanotic necrosis [FBcv_0000447]
Phenotype characterized by closely associated necrosis and melanization.
Minute [FBcv_0000443]
Dominant phenotype consisting of short slender bristles and delayed development. Homozygotes are cell lethal. The phenotype may be a general result of mutations in essential components of the protein synthesis pathway, as a number of Minutes encode ribosomal proteins. In an animal that is heterozygous for a Minute mutation, cells with two wild-type alleles of the affected gene have a growth advantage. Many developmental studies take advantage of this fact to give somatic clones a growth advantage. The term ‘Minute’ should not be used to annotate the resulting phenotypes.
modifier of variegation [FBcv_0000008]
Genotype g1 is a modifier of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is significantly different from that caused by g2 alone.
neoplasia [FBcv_0000723]
Phenotype that consists of abnormal growth of a tissue or organ due to increased numbers of cells, but in which the affected tissue or organ does not maintain its normal form.
neurogenic phenotype [FBcv_0000325]
A phenotype that is an expansion of the developing embryonic nervous system at the expense of developing ventral epidermis. Typically this is caused by and expansion of the population of neuroblasts at the expense of prospective epidermis, both of which originate in the ventral ectoderm.
non-enhancer of variegation [FBcv_0000380]
Genotype g1 is a non-enhancer of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not greater than that caused by g2 alone.
non-suppressor of variegation [FBcv_0000382]
Genotype g1 is a non-suppressor of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not less than that caused by g2 alone.
odd pair-rule phenotype [FBcv_0000701]
Embryonic/larval segmentation phenotype that is the complete or partial loss of odd segments. Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
pair rule phenotype [FBcv_0000699]
Embryonic/larval segmentation phenotype that is the complete or partial loss of alternate segments or parasegments. Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
paralytic [FBcv_0000389]
Phenotype that is a disposition to paralysis under conditions that do not cause paralysis in a wild-type animal. Paralysis is defined as an inability to exhibit multicellular organismal movement (GO:0050879)
partially lethal [FBcv_0002015]
A phenotype of a population that is the death of some significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
partially lethal - majority die [FBcv_0000352]
A phenotype of a population that is the death of a majority of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012). Stages during which there is significant death prior to mature adulthood can be indicated using one or more stage qualifiers.
partially lethal - majority live [FBcv_0000350]
A phenotype of a population that is the death of some significant proportion of animals in that population, but less that half, prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
phenotype [FBcv_0001347]
Any abnormality in or loss of some anatomical structure or biological process compared to wild-type. The subclasses of this term classify Drosophila phenotypes into different common categories. They have been chosen by FlyBase to reflect phenotype terms most often reported by Drosophila researchers in the published literature.
phenotypic class [FBcv_0000347]
[phenotypic class; specifically dependent continuant]
photoperiod response variant [FBcv_0000422]
Phenotype that is any abnormality in entrainment of circadian clock by photoperiod (GO:0043153), which is defined as: ‘The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).’
population of cells [FBcv_0006007]
[object aggregate; population of cells; has_member]
population of Drosophila [FBcv_0006003]
[population of organisms; multicellular organism; has_member; population of Drosophila]
premature aging [FBcv_0000792]
A phenotype in which the aging process (GO:0007568) is accelerated compared to wild-type.
project [FBcv_0003023]
A set of biological data from a single study. Corresponds to the NCBI bioproject, GEO series or SRA study.
radiation resistant [FBcv_0000441]
Phenotype that is a decreased tendency for radiation exposure to cause toxic effects.
radiation sensitive [FBcv_0000442]
Phenotype that is an increased tendency for radiation exposure to cause toxic effects.
result type [FBcv_0003082]
The type of result as characterized by its data content.
RNA-Seq [FBcv_0003068]
A quantitative method for mapping transcribed regions, in which complementary DNA fragments are subjected to high-throughput sequencing.
segment polarity phenotype [FBcv_0000702]
Embryonic/larval segmentation phenotype in which some fraction of each segment (along the anterior-posterior axis) is deleted and replaced by a mirror image duplication of the remaining part of the segment. Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns.
semi-fertile [FBcv_0000375]
A phenotype that is a reduction in the ability to produce fertilized eggs as a result of mating, but only to > 50% of wild-type.
semi-sterile [FBcv_0000365]
A phenotype that is a reduction in the ability to produce fertilized eggs as a result of mating to below 50% of wild-type.
short lived [FBcv_0000385]
Phenotype that is a shorter adult life-span than wild-type.
single-cell library sequencing [FBcv_0009005]
A method to prepare and sequence a library of cDNAs obtained from single cells.
single-cell RNA-Seq [FBcv_0009000]
A method for quantifying the transcriptome of individual cells, in which transcripts isolated from single cells are subjected to high-throughput sequencing and mapping to a reference genome.
single-nucleus RNA-Seq [FBcv_0009001]
A method for quantifying the transcriptome of individual cells, in which transcripts isolated from single nuclei are subjected to high-throughput sequencing and mapping to a reference genome.
Smart-seq2 [FBcv_0009007]
A method that uses the Smart-seq2 platform (Picelli et al., 2013) to prepare and sequence a cDNA library.
some die during embryonic stage [FBcv_0002041]
A phenotype of a population that is the death of a significant proportion of animals in that population during the embryonic stage.
some die during first instar larval stage [FBcv_0002021]
A phenotype of a population that is the death of a significant proportion of animals in that population during the first instar larval stage.
some die during immature adult stage [FBcv_0002051]
A phenotype of a population that is the death of some significant number of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012)).
some die during larval stage [FBcv_0002023]
A phenotype of a population that is the death of a significant proportion of animals in that population during the larval stage.
some die during P-stage [FBcv_0002020]
A phenotype of a population that is the death of a significant proportion of animals in that population during the P-stage.
some die during pharate adult stage [FBcv_0002038]
A phenotype of a population that is the death of a significant proportion of animals in that population during the pharate adult stage.
some die during prepupal stage [FBcv_0002040]
A phenotype of a population that is the death of a significant proportion of animals in that population during the prepupal stage.
some die during pupal stage [FBcv_0002039]
A phenotype of a population that is the death of a significant proportion of animals in that population during the pupal stage.
some die during second instar larval stage [FBcv_0002022]
A phenotype of a population that is the death of a significant proportion of animals in that population during the second instar larval stage.
some die during third instar larval stage [FBcv_0002024]
A phenotype of a population that is the death of a significant proportion of animals in that population during the third instar larval stage.
sterile [FBcv_0000364]
A phenotype that is the inability to produce fertilized eggs as a result of mating. The cause of sterility may be physical or behavioral. Note, this term should not be used with the qualifier ‘partially’. Use semi-sterile or semi-fertile instead.
suppressor of variegation [FBcv_0000381]
Genotype g1 is a suppressor of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is less than that caused by to g2 alone. Typically, g2 is a chromosomal aberration or an insertion.
terminal phenotype [FBcv_0000734]
Embryonic/larval segmentation phenotype that is the complete or partial loss of terminal regions of the embryo/larva: the acron, telson and immediately adjacent segments.
transcriptional cell cluster [FBcv_0009003]
A result that represents a population of cells sharing a similar transcriptional profile.
uncoordinated [FBcv_0000416]
Phenotype that is abnormal co-ordination of motor activity.
viable [FBcv_0000349]
A phenotype that is survival to mature adulthood, where mature is defined as after adult stage A3 (FBdv:00006012). Note, this term should not be used with the qualifier ‘partially’. Use semi-viable or semi-lethal instead.
visible [FBcv_0000354]
A post-embryonic, macroscopic, anatomical phenotype.
wild-type [FBcv_0000348]
The canonical phenotype of a wild-type Drosophilid.