NMDA glutamate receptor activity [GO_0004972]
An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages. The name of this receptor comes from its selective activation by N-methyl-D-aspartate (NMDA). Note that this term represents an activity and not a gene product.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen NMDA glutamate receptor activity in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004972",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004972",
"label": "NMDA glutamate receptor activity"
},
"description": [
"An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages."
],
"comment": [
"The name of this receptor comes from its selective activation by N-methyl-D-aspartate (NMDA). Note that this term represents an activity and not a gene product."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0022843",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0022843",
"label": "Hv1 Mediated H+ Permeability"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0004970",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004970",
"label": "ionotropic glutamate receptor activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0099094",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0099094",
"label": "ligand-gated cation channel activity"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "NMDA receptor",
"type": ""
},
"pub": {
"core": {
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],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_exact_synonym",
"label": "N-methyl-D-aspartate selective glutamate receptor activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": [
{
"core": {
"symbol": "",
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"types": [
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"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
]
}
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