negative regulation of excitatory postsynaptic potential [GO_0090394]
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen negative regulation of excitatory postsynaptic potential in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0090394",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0090394",
"label": "negative regulation of excitatory postsynaptic potential"
},
"description": [
"Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0048519",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0048519",
"label": "negative regulation of biological process"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0098815",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0098815",
"label": "modulation of excitatory postsynaptic potential"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002212",
"label": "negatively regulates",
"type": "negatively_regulates"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0060079",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0060079",
"label": "excitatory postsynaptic potential"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "negative regulation of excitatory post-synaptic membrane potential",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_related_synonym",
"label": "negative regulation of EPSP",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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