mRNA 5'-cap (guanine-N7-)-methyltransferase activity [GO_0004482]
Catalysis of the reaction: S-adenosyl-L-methionine + G(5’)pppR-RNA = S-adenosyl-L-homocysteine + m7G(5’)pppR-RNA. m7G(5’)pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen mRNA 5’-cap (guanine-N7-)-methyltransferase activity in VFB
Term Information
- ID: GO_0004482
- Name: mRNA 5’-cap (guanine-N7-)-methyltransferase activity
- Definition: Catalysis of the reaction: S-adenosyl-L-methionine + G(5’)pppR-RNA = S-adenosyl-L-homocysteine + m7G(5’)pppR-RNA. m7G(5’)pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.
- Synonyms:
- Type:
- Comment:
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004482",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004482",
"unique_facets": [
"Class"
],
"label": "mRNA 5'-cap (guanine-N7-)-methyltransferase activity"
},
"description": [
"Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "275438e",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0008174",
"types": [
"Entity",
"Class",
"has_subClass"
],
"short_form": "GO_0008174",
"unique_facets": [
"Class"
],
"label": "mRNA methyltransferase activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0008170",
"types": [
"Entity",
"Class",
"has_subClass"
],
"short_form": "GO_0008170",
"unique_facets": [
"Class"
],
"label": "N-methyltransferase activity"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0006370",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0006370",
"unique_facets": [
"Class"
],
"label": "7-methylguanosine mRNA capping"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0106005",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0106005",
"unique_facets": [
"Class"
],
"label": "RNA 5'-cap (guanine-N7)-methylation"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "messenger ribonucleate guanine 7-methyltransferase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"unique_facets": [
"pub"
],
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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