miRNA-mediated gene silencing by mRNA destabilization [GO_0035279]

An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.
Tags:

miRNA-mediated gene silencing by mRNA destabilization

ID: GO_0035279

Class

An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.

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Classification

Alternative Names

Synonym Scope Reference
deadenylation involved in gene silencing by miRNA related synonym
miRNA-mediated gene silencing by mRNA deadenylation related synonym
gene silencing by mRNA cleavage broad synonym
mRNA destabilization-mediated gene silencing by miRNA exact synonym
gene silencing by miRNA, mRNA cleavage exact synonym mah
miRNA-mediated gene silencing, mRNA cleavage exact synonym dph
mRNA cleavage involved in gene silencing by microRNA exact synonym pr
mRNA cleavage involved in gene silencing by miRNA exact synonym
mRNA deadenylation-mediated gene silencing by miRNA related synonym

References