histone H3R2 methyltransferase activity [GO_0070611]

Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to the arginine residue at position 2 of histone H3.
Tags:

histone H3R2 methyltransferase activity

ID: GO_0070611

Class

Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to the arginine residue at position 2 of histone H3.

Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.

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Classification

Alternative Names

Synonym Scope Reference
histone methyltransferase activity (H3-R2 specific) exact synonym
histone H3R2 arginine methyltransferase activity exact synonym
histone-arginine N-methyltransferase activity (H3-R2 specific) exact synonym mah
histone methylase activity (H3-R2 specific) exact synonym mah
histone-H3R2 methyltransferase activity exact synonym

References