histone H3K9me2/H3K9me3 demethylase activity [GO_0140684]

Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.

histone H3K9me2/H3K9me3 demethylase activity

ID: GO_0140684

Class

Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.

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Classification

Alternative Names

Synonym	Scope	Reference
histone H3K9me2 demethylase activity	broad synonym
histone H3-tri/dimethyl-lysine-9 demethylase activity	exact synonym
histone H3K9me3 demethylase activity	related synonym

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endent dioxygenase activity" } ], "relationships": [], "xrefs": [], "anatomy_channel_image": [], "pub_syn": [ { "synonym": { "scope": "has_exact_synonym", "label": "histone H3-tri/dimethyl-lysine-9 demethylase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "unique_facets": [ "pub" ], "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_broad_synonym", "label": "histone H3K9me2 demethylase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "unique_facets": [ "pub" ], "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_related_synonym", "label": "histone H3K9me3 demethylase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "unique_facets": [ "pub" ], "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } } ], "def_pubs": [] }

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