G-quadruplex DNA binding [GO_0051880]

Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.
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G-quadruplex DNA binding

ID: GO_0051880

Class

Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.

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Classification

Alternative Names

Synonym Scope Reference
G quartet binding broad synonym mah
G-quartet binding broad synonym mah
G quartet DNA binding exact synonym mah
G-quartet DNA binding exact synonym mah
tetraplex DNA binding exact synonym
G-DNA binding exact synonym
quadruplex DNA binding exact synonym
G quadruplex DNA binding exact synonym mah

References