DNA-templated transcription initiation [GO_0006352]

The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.
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DNA-templated transcription initiation

ID: GO_0006352

Class

The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.

Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.

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Classification

Relationships

Alternative Names

Synonym Scope Reference
transcription initiation, DNA-dependent related synonym jh2
transcription initiation from bacterial-type RNA polymerase promoter narrow synonym
DNA-dependent transcription, initiation exact synonym txnOH
DNA-templated transcription, initiation exact synonym
initiation of transcription, DNA-dependent exact synonym mah
DNA-dependent RNA polymerase complex assembly at promoter exact synonym
initiation of DNA-dependent transcription exact synonym jh2
transcription initiation factor activity related synonym

References