An ontology of genes present in Drosophila melanogaster scRNAseq data. Gene annotations include gene groups and GO molecular function annotations taken from FlyBase.
If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL
If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.
is a defining property chain axiom where second argument is reflexive
a core relation that holds between a part and its whole
part of
a core relation that holds between a whole and its part
has part
x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
preceded by
x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
precedes
b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
occurs in
[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
contains process
a relation between a continuant and a process, in which the continuant is somehow involved in the process
participates in
a relation between a process and a continuant, in which the continuant is somehow involved in the process
has participant
ends after
x overlaps y if and only if there exists some z such that x has part z and z part of y
overlaps
p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q.
regulates
p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q.
negatively regulates
p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q.
positively regulates
A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
capable of
c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
capable of part of
temporally related to
c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.
p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.
A mereological relationship or a topological relationship
mereotopologically related to
contributes to
c enables p iff c is capable of p and c acts to execute p.
enables
A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
functionally related to
this relation holds between c and p when c is part of some c', and c' is capable of p.
part of structure that is capable of
c involved_in p if and only if c enables some process p', and p' is part of p
involved in
enabled by
regulated by
negatively regulated by
positively regulated by
causally downstream of
relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
causally related to
p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.
causally upstream of
p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
inverse of causally upstream of or within
c involved in regulation of p if c is involved in some p' and p' regulates some p
c involved in regulation of p if c is involved in some p' and p' positively regulates some p
c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
involved in or involved in regulation of
c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
helper property (not for use in curation)
p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
A relationship between a material entity and a process where the material entity has some causal role that influences the process
p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
molecular interaction relation helper property
The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
causal relation between material entity and a process
Holds between c and p if and only if c is capable of some activity a, and a regulates p.
Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
acts upstream of or within, positive effect
acts upstream of or within, negative effect
c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
causally upstream of or within, negative effect
causally upstream of or within, positive effect
The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
Helper relation for OWL definition of RO:0018002 myristoylates
STRUCTURAL MAINTENANCE OF CHROMOSOMES GENE FAMILY
GOLGI-LOCALIZING, GAMMA-ADAPTIN EAR DOMAIN HOMOLOGY, ARF-BINDING PROTEINS
SYNAPTOTAGMINS & SYNAPTOTAGMIN-LIKE PROTEINS
SOLUBLE N-ETHYLMALEIMIDE-SENSITIVE FACTOR-ATTACHMENT PROTEINS
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-2
UNCLASSIFIED NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS
UNCLASSIFIED RING DOMAIN UBIQUITIN LIGASES
ACTIN-RELATED PROTEIN 2/3 COMPLEX ARPC3A VARIANT
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEXES
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1
INHIBITOR OF APOPTOSIS UBIQUITIN LIGASES
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-3
CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS
NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNITS
IONOTROPIC GLUTAMATE RECEPTOR SUPERFAMILY
ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT
AUTOPHAGY-SPECIFIC PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX
DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASES
CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASES
CONVENTIONAL MITOGEN ACTIVATED PROTEIN KINASES
ATYPICAL MITOGEN ACTIVATED PROTEIN KINASES
UNCLASSIFIED CONVENTIONAL PROTEIN KINASE DOMAIN KINASES
PHOSPHATIDYLINOSITOL PHOSPHATE AND INOSITOL PHOSPHATE PHOSPHATASES
PPP FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES
PPM FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES
UNCLASSIFIED PROTEIN SERINE/THREONINE PHOSPHATASES
POLYCOMB REPRESSIVE COMPLEX 1, PSC VARIANT
NUCLEOSOME REMODELING DEACETYLASE COMPLEX
POLYCOMB REPRESSIVE DEUBIQUITINASE COMPLEX
POLYCOMB REPRESSIVE COMPLEX 2, PCL VARIANT
CHROMATIN REMODELING COMPLEXES (ATP-DEPENDENT)
POLYBROMO-CONTAINING BRAHMA ASSOCIATED PROTEINS COMPLEX
POLYCOMB GROUP RECRUITERS/DNA-BINDING PROTEINS
ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEINS
RAS SUPERFAMILY GTPASE ACTIVATING PROTEINS
RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS - DENN DOMAIN
UNCLASSIFIED RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS
RAS SUPERFAMILY GUANINE NUCLEOTIDE EXCHANGE FACTORS
RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS - VPS9 DOMAIN
RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR COMPLEXES
TRANSCRIPTION FACTOR II H HOLOENZYME COMPLEX
TATA-BINDING PROTEIN AND TBP-RELATED FACTORS
CDK-ACTIVATING KINASE-XERODERMA PIGMENTOSUM D COMPLEX
TRANSCRIPTION FACTOR II H - CORE COMPLEX
TRANSIENT RECEPTOR POTENTIAL ION CHANNELS
NUCLEAR RECEPTOR (LIGAND-DEPENDENT) TRANSCRIPTION FACTORS
NUCLEAR RECEPTOR SUBFAMILY 0 (LIGAND-INDEPENDENT) TRANSCRIPTION FACTORS
AXONEMAL OUTER ARM DYNEIN INTERMEDIATE CHAINS
AXONEMAL INNER ARM DYNEIN INTERMEDIATE CHAINS
SPERM-SPECIFIC DYNEIN INTERMEDIATE CHAINS
MITOCHONDRIAL AMINOACYL-TRNA SYNTHETASES
DUAL-LOCALIZED AMINOACYL-TRNA SYNTHETASES
CYTOSOLIC ASPARTIC ACID-GTC TRANSFER RNAS
CYTOSOLIC GLUTAMIC ACID-CTC TRANSFER RNAS
CYTOSOLIC GLUTAMIC ACID-TTC TRANSFER RNAS
CYTOSOLIC PHENYLALANINE-GAA TRANSFER RNAS
CYTOSOLIC SELENOCYSTEINE-TCA TRANSFER RNAS
SURVIVAL MOTOR NEURON COMPLEX - GEM4A VARIANT
GOLGI-ASSOCIATED RETROGRADE PROTEIN COMPLEXES
GOLGI-ASSOCIATED RETROGRADE PROTEIN COMPLEX I
GOLGI-ASSOCIATED RETROGRADE PROTEIN COMPLEX II
MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) SUBUNITS
ATYPICAL HEAT SHOCK PROTEIN 70 CHAPERONES
VOLTAGE-GATED POTASSIUM CHANNEL - ALPHA SUBUNITS
HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP I
HEAT SHOCK PROTEIN 40/DNAJ CO-CHAPERONES
VOLTAGE-GATED POTASSIUM CHANNEL SUBUNITS
INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNITS
VOLTAGE-GATED POTASSIUM CHANNEL - BETA SUBUNITS
SLC21 FAMILY OF ORGANIC ANION TRANSPORTING POLYPEPTIDES
SPLICEOSOMAL SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLES
U1 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
U2 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
U4-U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
U5 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
U4-U6-U5 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNELS
ABCG ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY
ABCB ATP-BINDING CASSETTE TRANSPORTER ATM SUBFAMILY - HALF TRANSPORTERS
ATP-BINDING CASSETTE TRANSPORTER-LIKE - NON-TRANSPORTING
ABCD ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY
ABCA ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY
ABCB ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY
ABCF ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY
ABCC ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY
ABCE ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY
ABCH ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY
ABCB ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY - FULL TRANSPORTERS
GLUTAMATE-GATED CHLORIDE CHANNEL SUBUNITS
UNCLASSIFIED VOLTAGE-GATED CHLORIDE CHANNEL SUBUNITS
CALCIUM-ACTIVATED CHLORIDE CHANNEL SUBUNITS
CLC PLASMA MEMBRANE CHLORIDE CHANNEL SUBUNITS
HISTAMINE-GATED CHLORIDE CHANNEL SUBUNITS
NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE
CYTOPLASMIC TRANSLATION INITIATION FACTORS
CYTOPLASMIC TRANSLATION ELONGATION FACTORS
CYTOPLASMIC TRANSLATION RECYCLING AND REINITIATION FACTORS
MITOCHONDRIAL TRANSLATION INITIATION FACTORS
MITOCHONDRIAL TRANSLATION ELONGATION FACTORS
MITOCHONDRIAL TRANSLATION RELEASE FACTORS
MITOCHONDRIAL TRANSLATION RECYCLING FACTORS
VOLTAGE-GATED SODIUM CHANNEL ALPHA SUBUNITS
VOLTAGE-GATED SODIUM CHANNEL BETA SUBUNITS
UNCLASSIFIED CALCIUM CHANNEL-FORMING SUBUNITS
SODIUM CHANNEL-LIKE CATION CHANNEL SUBUNITS
VOLTAGE-GATED CALCIUM CHANNEL PORE SUBUNITS
CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL COMPLEX
SHORT PEPTIDOGLYCAN RECOGNITION PROTEINS
GLYCOSYLPHOSPHATIDYLINOSITOL ETHANOLAMINE-PHOSPHATE TRANSFERASE II COMPLEX
GLYCOSYLPHOSPHATIDYLINOSITOL TRANSAMIDASE COMPLEX
PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS GENES
GLYCOSYLPHOSPHATIDYLINOSITOL ETHANOLAMINE-PHOSPHATE TRANSFERASE III COMPLEX
GLYCOSYLPHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE I COMPLEX
PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS COMPLEXES
PHOSPHOLIPASE A2 ENZYMES - CALCIUM INDEPENDENT
U7 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
GLYCOSYLPHOSPHATIDYLINOSITOL-N-ACETYLGLUCOSAMINYLTRANSFERASE COMPLEX
SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLES
N-TERMINAL ACETYLTRANSFERASE CATALYTIC SUBUNITS
N-TERMINAL ACETYLTRANSFERASE AUXILIARY SUBUNITS
SLC38 FAMILY OF SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTERS
SLC8 FAMILY OF SODIUM/CALCIUM EXCHANGERS
SLC3 FAMILY OF HETEROMERIC AMINO ACID TRANSPORTERS ANCILLARY SUBUNITS
SLC22 FAMILY OF ORGANIC IONS TRANSPORTERS
SLC41 FAMILY OF MAGNESIUM ION TRANSPORTERS
SLC16 FAMILY OF MONOCARBOXYLATE TRANSPORTERS
SLC1 FAMILY OF GLUTAMATE AND NEUTRAL AMINO ACID TRANSPORTERS
SLC36 FAMILY OF PROTON-COUPLED AMINO ACID TRANSPORTERS
SLC32 FAMILY OF VESICULAR GABA TRANSPORTERS
SLC24 FAMILY OF POTASSIUM-DEPENDENT SODIUM/CALCIUM EXCHANGERS
SLC29 FAMILY OF EQUILIBRATIVE NUCLEOSIDE TRANSPORTERS
SLC18 FAMILY OF VESICULAR NEUROTRANSMITTER TRANSPORTERS
SLC13 FAMILY OF DICARBOXYLATE/CITRATE TRANSPORTERS
SLC28 FAMILY OF CONCENTRATIVE NUCLEOSIDE CO-TRANSPORTERS
SLC6 FAMILY OF SODIUM/CHLORIDE-DEPENDENT NEUROTRANSMITTER TRANSPORTERS
SLC5 FAMILY OF SODIUM-DEPENDENT SOLUTE TRANSPORTERS
SLC12 FAMILY OF CATION-COUPLED CHLORIDE TRANSPORTERS
SLC11 FAMILY OF PROTON-COUPLED METAL ION TRANSPORTERS
SLC35 FAMILY OF NUCLEOTIDE SUGAR TRANSPORTERS
SLC37 FAMILY OF PHOSPHOSUGAR/PHOSPHATE EXCHANGERS
SLC2 FAMILY OF HEXOSE SUGAR TRANSPORTERS
SLC20 FAMILY OF SODIUM/PHOSPHATE CO-TRANSPORTERS
SLC25 FAMILY OF MITOCHONDRIAL TRANSPORTERS
SLC17 FAMILY OF ORGANIC ANION TRANSPORTERS
NA[+]/K[+] TRANSPORTING P-ATPASE SUBUNITS
SARCO(ENDO)PLASMIC RETICULUM CALCIUM TRANSPORTING P-ATPASES
NA[+]/K[+] TRANSPORTING P-ATPASE - ALPHA SUBUNITS
NA[+]/K[+] TRANSPORTING P-ATPASE - BETA SUBUNITS
PLASMA MEMBRANE CALCIUM TRANSPORTING P-ATPASES
BASIC LEUCINE ZIPPER TRANSCRIPTION FACTORS
BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS
PAIRED-LIKE HOMEOBOX TRANSCRIPTION FACTORS
HIGH MOBILITY GROUP BOX TRANSCRIPTION FACTORS
ZINC FINGER HOMEOBOX TRANSCRIPTION FACTORS
SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS
SANT-MYB DOMAIN TRANSCRIPTION REGULATORS
REL HOMOLOGY DOMAIN TRANSCRIPTION FACTORS
MADF-BESS DOMAIN TRANSCRIPTION REGULATORS
A-T RICH INTERACTION DOMAIN TRANSCRIPTION FACTORS
NUCLEAR FACTOR OF ACTIVATED T-CELLS TRANSCRIPTION FACTORS
IMMUNOGLOBULIN FOLD TRANSCRIPTION FACTORS
GLIAL CELL MISSING TRANSCRIPTION FACTORS
A-T RICH INTERACTION DOMAIN TRANSCRIPTION REGULATORS
MAD HOMOLOGY DOMAIN TRANSCRIPTION FACTORS
UNCLASSIFIED DNA BINDING DOMAIN TRANSCRIPTION FACTORS
POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES
RACEMASES AND EPIMERASES ACTING ON CARBOHYDRATES AND DERIVATIVES
INTRAMOLECULAR OXIDOREDUCTASES INTERCONVERTING ALDOSES AND KETOSES
INTRAMOLECULAR OXIDOREDUCTASES TRANSPOSING C-C DOUBLE BONDS
CARBON-NITROGEN LIGASES, WITH GLUTAMINE AS AMIDO-N-DONOR
ENDOPLASMIC RETICULUM CLASS I ALPHA-MANNOSIDASES
ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASES
DNA-(APURINIC OR APYRIMIDINIC SITE) LYASES
CARBON-OXYGEN LYASES, ACTING ON PHOSPHATES
JAK-STAT SIGNALING PATHWAY CORE COMPONENTS
POSITIVE REGULATORS OF JAK-STAT SIGNALING PATHWAY
NEGATIVE REGULATORS OF JAK-STAT SIGNALING PATHWAY
WNT-TCF SIGNALING PATHWAY CORE COMPONENTS
NEGATIVE REGULATORS OF WNT-TCF SIGNALING PATHWAY
POSITIVE REGULATORS OF WNT-TCF SIGNALING PATHWAY
BETA CATENIN DESTRUCTION COMPLEX APC VARIANT
POSITIVE REGULATORS OF INSULIN-LIKE RECEPTOR SIGNALING PATHWAY
NEGATIVE REGULATORS OF INSULIN-LIKE RECEPTOR SIGNALING PATHWAY
CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX
INSULIN-LIKE RECEPTOR SIGNALING PATHWAY CORE COMPONENTS
POSITIVE REGULATORS OF HIPPO SIGNALING PATHWAY
STRIATIN-INTERACTING PHOSPHATASE AND KINASE COMPLEX
NEGATIVE REGULATORS OF HIPPO SIGNALING PATHWAY
CH-OH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
UNCLASSIFIED ALCOHOL DEHYDROGENASES (NAD-DEPENDENT)
UNCLASSIFIED CH-OH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASES
SEVENLESS SIGNALING PATHWAY CORE COMPONENTS
POSITIVE REGULATORS OF TORSO SIGNALING PATHWAY
POSITIVE REGULATORS OF SEVENLESS SIGNALING PATHWAY
NEGATIVE REGULATORS OF TORSO SIGNALING PATHWAY
NEGATIVE REGULATORS OF SEVENLESS SIGNALING PATHWAY
GLYCEROL-3-PHOSPHATE DEHYDROGENASES (QUINONE)
PROTEIN PHOSPHATASE 2 PHOSPHATASE ACTIVATORS
NEGATIVE REGULATORS OF EGFR SIGNALING PATHWAY
POSITIVE REGULATORS OF EGFR SIGNALING PATHWAY
ACYL-COA BINDING DOMAIN-CONTAINING PROTEINS
NEGATIVE REGULATORS OF FGFR SIGNALING PATHWAY
POSITIVE REGULATORS OF FGFR SIGNALING PATHWAY
NEGATIVE REGULATORS OF PVR SIGNALING PATHWAY
POSITIVE REGULATORS OF PVR SIGNALING PATHWAY
HEDGEHOG SIGNALING PATHWAY CORE COMPONENTS
NEGATIVE REGULATORS OF HEDGEHOG SIGNALING PATHWAY
POSITIVE REGULATORS OF HEDGEHOG SIGNALING PATHWAY
ALDEHYDE OR OXO OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR
ALDEHYDE OR OXO OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
ALDEHYDE OR OXO OXIDOREDUCTASES, WITH OXYGEN AS ACCEPTOR
CH-CH OXIDOREDUCTASES, OXYGEN AS ACCEPTOR
CH-CH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
CH-NH2 OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR
CH-NH2 OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
CH-NH2 OXIDOREDUCTASES, OXYGEN AS ACCEPTOR
CH-NH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
NAD(P)H OXIDOREDUCTASES, OXYGEN AS ACCEPTOR
NAD(P)H OXIDOREDUCTASES, HEME PROTEIN AS ACCEPTOR
SULFUR OXIDOREDUCTASES, OXYGEN AS ACCEPTOR
SULFUR OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR
SULFUR OXIDOREDUCTASES, NAD(P) AS ACCEPTOR
MITOCHONDRIAL COMPLEX IV - CORE SUBUNITS
DIPHENOL OXIDOREDUCTASES, OXYGEN AS ACCEPTOR
MITOCHONDRIAL COMPLEX III - CORE SUBUNITS
METAL ION OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
UNCLASSIFIED 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES
MONOOXYGENASES, REDUCED ASCORBATE AS ONE DONOR
MONOOXYGENASES, REDUCED PTERIDINE AS ONE DONOR
NEGATIVE REGULATORS OF TOLL-NF-kappaB SIGNALING PATHWAY
NEGATIVE REGULATORS OF SPATZLE ACTIVATING PATHWAY
EXTRACELLULAR SPATZLE ACTIVATING PATHWAY CORE COMPONENTS
POSITIVE REGULATORS OF TOLL-NF-kappaB SIGNALING PATHWAY
TOLL-NF-kappaB SIGNALING PATHWAY CORE COMPONENTS
1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASES
NEGATIVE REGULATORS OF NOTCH SIGNALING PATHWAY
CSL-NOTCH-MASTERMIND TRANSCRIPTION FACTOR COMPLEX
POSITIVE REGULATORS OF NOTCH SIGNALING PATHWAY
ALL-TRANS-RETINOL DEHYDROGENASES (NAD-DEPENDENT)
GLYCEROL-3-PHOSPHATE DEHYDROGENASES (NAD+)
S1A SERINE PROTEASES - CHYMOTRYPSIN-LIKE
NEGATIVE REGULATORS OF BMP SIGNALING PATHWAY
NEGATIVE REGULATORS OF ACTIVIN SIGNALING PATHWAY
ACTIVIN SIGNALING PATHWAY CORE COMPONENTS
POSITIVE REGULATORS OF BMP SIGNALING PATHWAY
POSITIVE REGULATORS OF ACTIVIN SIGNALING PATHWAY
UNCLASSIFIED ALKYL OR ARYL (OTHER THAN METHYL) TRANSFERASES
HYDROXYMETHYL-, FORMYL- AND RELATED TRANSFERASES
CHITIN BINDING DOMAIN-CONTAINING PROTEINS
NUCLEAR FACTOR - KAPPA B INHIBITOR FAMILY
NEGATIVE REGULATORS OF IMD SIGNALING PATHWAY
POSITIVE REGULATORS OF IMD SIGNALING PATHWAY
UNCLASSIFIED NON-AMINOACYL ACYLTRANSFERASES
UNCLASSIFIED CH-CH OXIDOREDUCTASES, OXYGEN AS ACCEPTOR
UNCLASSIFIED LYSOPHOSPHOLIPID ACYLTRANSFERASES
UNCLASSIFIED PHOSPHORUS-CONTAINING GROUP TRANSFERASES
PHOSPHORUS-CONTAINING GROUP TRANSFERASES
SERINE AND ARGININE RICH SPLICING FACTORS
CANONICAL SERINE AND ARGININE RICH SPLICING FACTORS
NON-CANONICAL SERINE AND ARGININE RICH SPLICING FACTORS
CYCLIC NUCLEOTIDE-ACTIVATED CATION CHANNELS
CYCLIC NUCLEOTIDE-GATED CHANNEL SUBUNITS
ER MEMBRANE PROTEIN COMPLEX EMC2A VARIANT
UNCLASSIFIED PROTEIN-LYSINE N-METHYLTRANSFERASES
CARBON-NITROGEN HYDROLASES (NON-PEPTIDASE)
CARBON-NITROGEN HYDROLASES OF LINEAR AMIDES
BETA 1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE
MANNOSYL-GLYCOPROTEIN N-ACETYLGLUCOSAMINYLTRANSFERASES
PROTEOGLYCAN N-ACETYLGLUCOSAMINYLTRANSFERASES
BETA-N-ACETYLGLUCOSAMINE BETA-1,3-GALACTOSYLTRANSFERASES
DOLICHYL PYROPHOSPHATE GLUCOSYLTRANSFERASES
DOLICHYL PYROPHOSPHATE MANNOSYLTRANSFERASES
UNCLASSIFIED CARBON-NITROGEN HYDROLASES OF CYCLIC AMIDINES
CARBON-NITROGEN HYDROLASES OF LINEAR AMIDINES
CARBON-NITROGEN HYDROLASES OF CYCLIC AMIDES
DOLICHOL-PHOSPHATE-MANNOSE SYNTHASE COMPLEX
UNCLASSIFIED CARBON-NITROGEN HYDROLASES OF LINEAR AMIDES
UNCLASSIFIED CARBOXYLIC ESTER HYDROLASES
MITOCHONDRIAL COMPLEX I - ACCESSORY SUBUNITS
ANGIOTENSIN-CONVERTING ENZYME-LIKE PEPTIDYL-DIPEPTIDASES
GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASES
UNCLASSIFIED PHOSPHORIC DIESTER HYDROLASES
UBIQUITIN-LIKE PROTEIN CYSTEINE PROTEASES
UBIQUITIN-LIKE PROTEIN METALLOPEPTIDASES
CLASS II APURINIC OR APYRIMIDINIC ENDONUCLEASES
PROTEASOME REGULATORY PARTICLE NON-ATPASES
VACUOLAR ATPASE V1 DOMAIN CATALYTIC SUBUNITS
VACUOLAR ATPASE V1 DOMAIN NON-CATALYTIC SUBUNITS
TNFalpha-EIGER SIGNALING PATHWAY CORE COMPONENTS
NEGATIVE REGULATORS OF TNFalpha-EIGER SIGNALING PATHWAY
POSITIVE REGULATORS OF TNFalpha-EIGER SIGNALING PATHWAY
CTD FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES
EYA FAMILY PROTEIN TYROSINE PHOSPHATASES
GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASES
UNCLASSIFIED ALDEHYDE OR OXO OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
POSITIVE TRANSCRIPTION ELONGATION FACTOR COMPLEX B
IRRE CELL RECOGNITION MODULE CELL ADHESION MOLECULES
NON-CANONICAL BRAHMA ASSOCIATED PROTEINS COMPLEX
SLC10 FAMILY OF SODIUM-BILE ACID CO-TRANSPORTERS
SLC49 FAMILY OF FLVCR-RELATED TRANSPORTERS
SLC66 FAMILY OF LYSOSOMAL AMINO ACID TRANSPORTERS
SLC23 FAMILY OF ASCORBIC ACID TRANSPORTERS
SLC57 FAMILY OF NIPA-LIKE MAGNESIUM TRANSPORTERS
SLC58 FAMILY OF MAGT-LIKE MAGNESIUM TRANSPORTERS
SLC65 FAMILY OF NPC-TYPE CHOLESTEROL TRANSPORTERS
SLC55 FAMILY OF MITOCHONDRIAL CATION/PROTON EXCHANGERS
SLC54 FAMILY OF MITOCHONDRIAL PYRUVATE CARRIERS
SLC63 FAMILY OF SPHINGOSINE PHOSPHATE TRANSPORTERS
SLC64 FAMILY OF GOLGI CA2+/H+ EXCHANGERS
MITOCHONDRIAL COMPLEX III - SUPERNUMERARY SUBUNITS
MITOCHONDRIAL COMPLEX IV - SUPERNUMERARY SUBUNITS
ALL-TRANS-RETINOL DEHYDROGENASES (NADP-DEPENDENT)
UNCLASSIFIED ALCOHOL DEHYDROGENASES (NADP-DEPENDENT)
CH-NH OXIDOREDUCTASES, OXYGEN AS ACCEPTOR
UNCLASSIFIED SULFUR OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR
UNCLASSIFIED SULFUR OXIDOREDUCTASES, NAD(P) AS ACCEPTOR
SULFUR OXIDOREDUCTASES, QUINONE AS ACCEPTOR
PYRUVATE DEHYDROGENASES (ACETYL-TRANSFERRING)
TRANSCRIPTION ELONGATION FACTOR COMPLEXES
RNA POLYMERASE-ASSOCIATED FACTOR 1 COMPLEX
GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASES
ATP-DEPENDENT PROTEIN FOLDING CHAPERONES
SMALL NUCLEOLAR RIBONUCLEOPROTEIN COMPLEXES
H/ACA SMALL NUCLEOLAR RIBONUCLEOPROTEIN COMPLEX
C/D SMALL NUCLEOLAR RIBONUCLEOPROTEIN COMPLEX
TESTIS-SPECIFIC GAMMA-TUBULIN RING COMPLEX
NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNITS
NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX ALPHA SUBUNITS
NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX BETA SUBUNITS
UNCLASSIFIED PROTEIN-LYSINE ACETYLTRANSFERASES
CGAS-STING SIGNALING PATHWAY CORE COMPONENTS
ACTIN-RELATED PROTEIN 2/3 COMPLEX ARPC3B VARIANT
MEIOTIC COHESIN COMPLEX SOLO-SUNN VARIANT
BETA CATENIN DESTRUCTION COMPLEX APC2 VARIANT
ER MEMBRANE PROTEIN COMPLEX EMC2B VARIANT
UNCLASSIFIED SULFUR GROUP OXIDOREDUCTASES
GENERAL TRANSCRIPTION FACTOR II A COMPLEX - TFIIA-S VARIANT
GENERAL TRANSCRIPTION FACTOR II A COMPLEX - GERMLINE SPECIFIC VARIANT
N-TERMINAL ACETYLTRANSFERASE C COMPLEX - TESTIS-SPECIFIC VARIANT
COP9 SIGNALOSOME COMPLEX - TESTIS-SPECIFIC VARIANT
SURVIVAL MOTOR NEURON COMPLEX - GEM4B VARIANT
SURVIVAL MOTOR NEURON COMPLEX - GEM4C VARIANT
MITOCHONDRIAL COMPLEX I - TESTIS-SPECIFIC VARIANT
26S PROTEASOME - TESTIS-SPECIFIC VARIANT
MITOCHONDRIAL COMPLEX IV - TESTIS-SPECIFIC VARIANT
MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE)
MITOCHONDRIAL COMPLEX III - TESTIS-SPECIFIC VARIANT
MITOCHONDRIAL COMPLEX V - TESTIS-SPECIFIC VARIANT
MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) - TESTIS-SPECIFIC VARIANT
SEC61 TRANSLOCON - TESTIS-SPECIFIC VARIANT
PHTF PUTATIVE SEVEN TRANSMEMBRANE DOMAIN ION CHANNELS
CITRATE TRANSPORTER-LIKE DOMAIN/ARSB-LIKE TRANSPORTERS
ION CHANNELS OF UNCLASSIFIED CONDUCTANCE
POLYCOMB REPRESSIVE COMPLEX 1, SU(Z)2 VARIANT
POLYCOMB REPRESSIVE COMPLEX 2, JARID2-JING VARIANT
OXOGLUTARATE DEHYDROGENASE COMPLEX - OGDH1 VARIANT
KINETOCHORE MIS12 COMPLEX - NF1B VARIANT
KINETOCHORE MIS12 COMPLEX - NF1A VARIANT
OXOGLUTARATE DEHYDROGENASE COMPLEX VARIANTS
OXOGLUTARATE DEHYDROGENASE COMPLEX - OGDH2 VARIANT
INTRACELLULAR CALCIUM-RELEASE CHANNEL SUBUNITS
TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING PROTEIN FAMILY
CNNM-TYPE Mg[2+]-EFFLUX TRANSPORTER SUBUNITS
CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL SUBUNITS
TMEM63 MECHANICALLY ACTIVATED ION CHANNEL SUBUNITS
TRANSMEMBRANE CHANNEL-LIKE FAMILY SUBUNITS
TRIMERIC INTRACELLULAR CATION CHANNEL SUBUNITS
VOLTAGE-GATED CALCIUM CHANNEL ACCESSORY SUBUNITS
MITOCHONDRIAL CALCIUM UNIPORTER COMPLEX - CG4704 VARIANT
MITOCHONDRIAL CALCIUM UNIPORTER COMPLEXES
P4-ATPASE PHOSPHOLIPID FLIPPASE SUBUNITS
P4-ATPASE PHOSPHOLIPID FLIPPASE ACCESSORY SUBUNITS
TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE COMPLEXES
TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE COMPLEX - TESTIS-SPECIFIC VARIANT
TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE COMPLEX
TIM22 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE COMPLEX
TIM23 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE COMPLEX SUBUNITS
PRESEQUENCE TRANSLOCASE-ASSOCIATED MOTOR SUBUNITS
LKB1-STRAD-MO25 SERINE/THREONINE PROTEIN KINASE COMPLEX
ENDOPLASMIC RETICULUM SEC TRANSLOCON COMPLEXES
MITOCHONDRIAL ALPHA-KETOACID DEHYDROGENASE COMPLEXES
PYRUVATE DEHYDROGENASE COMPLEX - PDHA1 VARIANT
PYRUVATE DEHYDROGENASE COMPLEX - PDHA2 VARIANT
BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE COMPLEX
YIDC/ALB3/OXA1 MEMBRANE PROTEIN INSERTASE FAMILY
OXIDOREDUCTION-DRIVEN TRANSMEMBRANE TRANSPORTERS
MECHANOSENSITIVE PICKPOCKET ION CHANNELS
MECHANOSENSITIVE TRANSIENT RECEPTOR POTENTIAL ION CHANNELS
POSITIVE REGULATORS OF CGAS-STING SIGNALING PATHWAY
MITOCHONDRIAL CONTACT SITE AND CRISTAE ORGANIZING SYSTEM COMPLEXES
MICOS COMPLEX - MIC10C TESTIS-SPECIFIC VARIANT
MICOS COMPLEX - MIC10A TESTIS-SPECIFIC VARIANT
MPV17/PMP22 PUTATIVE MITOCHONDRIAL CHANNEL FAMILY
UNCLASSIFIED LIGAND-GATED ION CHANNEL SUBUNITS
PEROXISOMAL UBIQUITIN LIGASE RETROTRANSLOCON COMPLEX
PEROXISOMAL DOCKING AND TRANSLOCATION MODULE
ENDOPLASMIC RETICULUM SECRETORY AND TRANSMEMBRANE PROTEIN INSERTION SYSTEM COMPLEXES
SLC25 FAMILY OF MITOCHONDRIAL AND PEROXISOMAL TRANSPORTERS
SLC25 FAMILY OF PEROXISOMAL TRANSPORTERS
PANORAMIX-INDUCED CO-TRANSCRIPTIONAL SILENCING COMPLEX
MITOCHONDRIAL COMPLEX I INTERMEDIATE ASSEMBLY COMPLEX
MPV17/PMP22 PUTATIVE PEROXISOMAL CHANNEL FAMILY
UNCLASSIFIED CH-CH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR
ABCB ATP-BINDING CASSETTE TRANSPORTER HMT-1 SUBFAMILY - HALF TRANSPORTERS
ERF1-ERF3 TRANSLATION TERMINATION COMPLEX
NXF1-NXT1 MRNA NUCLEAR EXPORT FACTOR COMPLEX
DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF VARIANT
DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF2 VARIANT
MYB-MUVB TRANSCRIPTIONAL ACTIVATION COMPLEX
TDRD3-TOP3B TYPE IA TOPOISOMERASE COMPLEX
DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX
GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE COMPLEX
MITOCHONDRIAL TRIFUNCTIONAL PROTEIN COMPLEX
UDP-N-ACETYLGLUCOSAMINE TRANSFERASE COMPLEX
MITOCHONDRIAL INTERMEMBRANE SPACE TIM CHAPERONE COMPLEXES
TIM8-TIM13 COMPLEX - TIM13 VARIANT (TESTIS)
MXR METABOTROPIC GLUTAMATE-LIKE RECEPTORS
SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS
CALCIUM AND VOLTAGE-ACTIVATED LARGE CONDUCTANCE POTASSIUM CHANNELS
SODIUM AND VOLTAGE-ACTIVATED LARGE CONDUCTANCE POTASSIUM CHANNELS
CLC ENDOLYSOSOMAL CHLORIDE/PROTON ANTIPORTERS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX III ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRASOME ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX II ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX IV ASSEMBLY FACTORS
MITOCHONDRIAL PROTON-TRANSPORTING ATP SYNTHASE COMPLEX ASSEMBLY FACTORS
MITOCHONDRIAL OXPHOS COMPLEX ASSEMBLY FACTORS
3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE (PAPS) BIOSYNTHESIS
CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHESIS
CHONDROITIN SULFATE PROTEOGLYCAN CATABOLISM
HEPARAN SULFATE PROTEOGLYCAN BIOSYNTHESIS
NAD(+) BIOSYNTHESIS VIA THE SALVAGE PATHWAY
CYTOSOLIC 4FE-4S ASSEMBLY SCAFFOLD COMPLEX
CYTOSOLIC 4FE-4S ASSEMBLY TARGETING COMPLEX
CH-CH OXIDOREDUCTASES, QUINONE AS ACCEPTOR
VERY-LONG-CHAIN 3-OXOACYL-COA REDUCTASES
GLYOXYLATE AND HYDROXYPYRUVATE REDUCTASES
UNCLASSIFIED N-ACETYLGLUCOSAMINYLTRANSFERASES
RNA POLYMERASE-ASSOCIATED FACTOR 1 COMPLEX - TESTIS-SPECIFIC VARIANT
CARBON-NITROGEN HYDROLASES OF CYCLIC AMIDINES
METTL1-WUHO TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE COMPLEX
ATR-ATRIP DNA DAMAGE-SENSING KINASE COMPLEX
DOLICHOL-LINKED OLIGOSACCHARIDE BIOSYNTHESIS
CYTOPLASMIC SMALL RIBOSOMAL SUBUNIT - TESTIS-SPECIFIC VARIANT
CYTOPLASMIC LARGE RIBOSOMAL SUBUNIT - TESTIS-SPECIFIC VARIANT
MITOCHONDRIAL PYRUVATE CARRIER COMPLEX - Mpc2b VARIANT
MITOCHONDRIAL PYRUVATE CARRIER COMPLEX - Mpc2a VARIANT
COFACTORS, CARRIERS AND VITAMIN METABOLISM
MITOCHONDRIAL PROCESSING PEPTIDASE COMPLEX
MITOCHONDRIAL INNER MEMBRANE PEPTIDASE COMPLEX
SINGLE VON WILLEBRAND FACTOR TYPE C DOMAIN PROTEINS
TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE SORT COMPLEX
TIM23 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE MOTOR COMPLEX
SORTING AND ASSEMBLY MACHINERY COMPLEX - Mtx2 VARIANT
SORTING AND ASSEMBLY MACHINERY COMPLEX - CG5662 VARIANT
L-PHENYLALANINE AND L-TYROSINE METABOLISM
L-GLUTAMATE BIOSYNTHESIS (FROM L-PROLINE)
MITOCHONDRIAL CALCIUM UNIPORTER CHANNEL SUBUNITS
CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL SUBUNITS
HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP II
RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS - TRI LONGIN DOMAIN
TRAPP GUANINE NUCLEOTIDE EXCHANGE FACTOR CATALYTIC CORE SUBUNITS
DEHYDRO-N-BETA-ALANYLDOPAMINE BIOSYNTHESIS
Signal recognition particle 7SL RNA CR32864
Nicotinic Acetylcholine Receptor alpha-96Aa
nicotinic Acetylcholine Receptor alpha 96Aa
nicotinic acetylcholine receptor alpha-like
muscarinic Acetylcholine Receptor, A-type
nicotinic Acetylcholine Receptor beta 64B
Dalpha2 nicotimic acetylcholine receptor
nicotinic Acetylcholine Receptor alpha 96Ab
nicotinic acetylcholine receptor alpha subunit gene at 96AB
nicotinic acetylcholine receptor alpha-2
Phosphoribosylformylglycinamidine synthase
Drosophila Rhythmically expressed gene 1
3,4-dihydroxyphenylacetaldehyde synthase
crossover suppressor in chromosome 3 of Gowen
Protein kinase, cAMP-dependent, catalytic subunit 1
catalytic subunit of cAMP-dependent protein kinase
Protein kinase, cAMP-dependent, catalytic subunit 2
N-ethyl-maleimide sensitive fusion protein
N-ethylmaleimide-sensitive fusion protein
Drosophila Aggregation promoting activity
3,4-Dihydroxyphenylalanine decarboxylase
L-3,4-dihydroxyphenylalanine decarboxylase
Small ribonucleoprotein particle protein SmF
Protein kinase, cAMP-dependent, catalytic subunit 3
Decapentaplegic/Bone Morphogenetic Protein
eukaryotic translation elongation factor 1 alpha 2
eukaryotic translation elongation factor 2
eukaryotic translation elongation factor 2b
Stress-inducible humoral factor Turandot A
Fork head, which is crucial for survival, is enriched in the MT transcriptome, and its down regulation in
Adaptor Protein complex 3, delta subunit
Glyceraldehyde 3 phosphate dehydrogenase
Glyceraldehyde 3 phosphate dehydrogenase 1
Glyceraldehyde-3-phosphate dehydrogenase
Glyceraldehyde-3-phosphate dehydrogenase 1
Glyceraldehyde-3-phosphate dehydrogenase1
glyceraldehyde 3 phosphate dehydrogenase1
Glyceraldehyde 3 phosphate dehydrogenase 2
Glyceraldehyde-3-phosphate dehydrogenase 2
glyceraldehyde 3-phosphate dehydrogenase
NADP-dependent GDH glutamate dehydrogenase
mitochondrial aspartate aminotransferase
alpha-glycerol-3-phosphate dehydrogenase
GABA and glycine-like receptor of Drosophila
GABA/Glycine-gated chloride channel-like
Heterogeneous nuclear ribonucleoprotein at 98DE
70 kDa heat shock protein, cytosolic B 1
70 kDa heat shock protein, cytosolic A 8
70 kDa heat shock protein, endoplasmic reticulum 1
glucose-regulated protein 78kD/binding immunoglobulin protein
70 kDa heat shock protein, mitochondrial 1
heat shock protein family B (small) member 1
70 kDa heat shock protein, cytosolic A 7
neural and ectodermal development factor
lethal(1)benign wing imaginal disc neoplasm
eukaryotic translation initiation factor 4A
Actin-related protein 2/3 complex, subunit 1
Polypeptide N-acetylgalactosaminyltransferase 35A
NADH dehydrogenase (ubiquinone) B17 subunit
NADH-ubiquinone oxidoreductase B17 subunit
NADH:ubiquinone oxidoreductase B17 subunit
Ca[2+]-channel protein alpha[[1]] subunit D
Drosophila melanogaster calcium channel alpha[[1]] subunit DHP-sensitive
Drosophila melanogaster calcium channel α[[1]] subunit DHP-sensitive
mitochondrial ribosomal protein large subunit 4
Negative transcription elongation factor 2
Enhancer of split m2, Bearded family member
Enhancer of split m4, Bearded family member
Enhancer of split m6, Bearded family member
Regulator of chromosome condensation 1 ortholog
Enhancer of split malpha, Bearded family member
Enhancer of split mα, Bearded family member
Enhancer of split mbeta, helix-loop-helix
Enhancer of split region transcript HLHmA
Enhancer of split mdelta, helix-loop-helix
Enhancer of split region transcript HLHmC
Enhancer of split mgamma, helix-loop-helix
Enhancer of split region transcript HLHmB
muscle-specific myosin regulatory light chain
sodium/potassium transporting ATPase alpha
Neither inactivation nor after potential
either inactivation nor afterpotential A
neither inactivation nor afterpotential A
neither inactivation nor afterpotential B
Neither Inactivation Nor Afterpotential C
Neither inactivation nor after potential C
either inactivation nor afterpotential C
neither inactivation nor afterpotential-C
neither inactivation nor afterpotential D
Neither inactivation nor afterpotential E
Adaptor Protein complex 3, sigma subunit
Histamine-gated chloride channel subunit 2
histamine-gated chloride channel subunit 1
protein phosphatase from PCR fragment D19
leucine-rich repeat-containing G protein-coupled receptor 2
absent MD neurons and olfactory sensilla
Drosophila Protein O-mannosyltransferase 1
Shaggy/Zeste-white-3/Glycogen synthase kinase 3beta
Shaggy/Zeste-white-3/Glycogen synthase kinase 3β
Drosophila melanogaster epithelial (DE)-cadherin
Suppressor of constitutively activated Dpp signaling 78
non-muscle myosin II regulatory light chain
nonmuscle myosin II regulatory light chain
regulatory light chain of nonmuscle myosin II
regulatory light chain of nonmuscle myosin-II
cytoplasmic dynein intermediate polypeptide chain
Drosophila epidermal growth factor receptor
Drosophila epidermal growth factor receptor homologue
blistered/Drosophila serum response factor
nicotinic Acetylcholine Receptor beta 96A
5-hydroxytryptamine (serotonin) receptor 1A
catalytic subunit C of type 2A protein phosphatase
Heterogeneous nuclear ribonucleoprotein at 85CD
Heterogeneous nuclear ribonucleoprotein at 87F
VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL
Cyclic-AMP response element binding protein A
cyclic AMP response element binding protein
catalytic subunit of the mitochondrial DNA polymerase
Mitochondrial DNA polymerase accessory subunit
accessory subunit of mitochondrial DNA polymerase
Drosophila male specific opa containing gene
5-hydroxytryptamine (serotonin) receptor 7
glutamate receptor kainate-selective subunit
guanine nucleotide regulatory protein beta subunit
alkali light chain of non-muscle myosin-II
essential myosin light chain-cytoplasmic
Xeroderma pigmentosum, complementation group C
xeroderma pigmentosum group C complementing factor
Heterogeneous nuclear ribonucleoprotein at 27C
Succinyl coenzyme A synthatase, alpha subunit
Succinyl coenzyme A synthetase alpha subunit
Succinyl coenzyme A synthetase α subunit
Succinyl-coenzyme A synthetase alpha subunit 1
Succinyl-coenzyme A synthetase α subunit 1
regulatory B subunit of type 2A protein phosphatase
antisense RNA:Ecdysone-induced gene 63F 2
eukaryotic translation initiation factor 2 subunit beta
U2 small nuclear riboprotein auxiliary factor 50
transfer RNA-Glu-Pro aminoacyl synthetase
DNA polymerase alpha 73,000 alpha subunit
DNA polymerase alpha primase 73 kda subunit
protein phosphatase from PCR fragment D3
protein phosphatase from PCR fragment D5
protein phosphatase from PCR fragment D6
protein phosphatase from PCR fragment D14
Inositol(1,4,5)-triphosphate receptor 42B
inositol 1,4,5-trisphosphate (InsP3 ) receptor
ATP synthase subunit beta, mitochondrial
NAD dependent methylenetetrahydrofolate dehydrogenase
NAD-dependent methylenetetrahydrofolate dehydrogenase
kinesin light chain subunit of kinesin-1
ligand-gated chloride channel homologue 3
Mitogen-activated protein kinase kinase 7
dacapo/cyclin-dependent kinase interactor 4
Translocase of inner mitochondrial membrane domain containing 1
alpha-ketoglutarate dehydrogenase E1 subunit
α-ketoglutarate dehydrogenase E1 subunit
Adaptor Protein complex 1/2, beta subunit
Signal recognition particle receptor alpha
mitochondrial single strand binding protein
mitochondrial single stranded DNA-binding protein
mitochondrial single-stranded DNA-binding
mitochondrial single-stranded DNA-binding protein
Dietary and metabolic glutamate transporter
Electron transfer flavoprotein alpha subunit
Electron transfer flavoprotein alpha-subunit
Copper chaperone for superoxide dismutase
sex-determining region Y protein-interacting protein-1
Major Facilitator Superfamily Transporter 14
Coiled-coil-helix-coiled-coil-helix domain containing 3
alpha subunit of the mitochondrial F[[1]]F[[0]] ATPase
mitochondrial ATP synthase alpha subunit
mitochondrial ATP synthase subunit alpha of complex V
mitochondrial ATPase complex V-subunit alpha
mitochondrial ATPase complex V-subunit α
α subunit of the mitochondrial F[[1]]F[[0]] ATPase
Heterogeneous Nuclear RibonucleoProtein I
Ubiquinol-cytochrome C reductase complex 7.2 kDa protein
Ubiquinol-cytochrome c oxidoreductase 7.2 kDa
Ubiquinol-cytochrome c reductase 7.2 kDa protein
Pheromone-binding protein-related protein 1
Pheromone-binding protein-related protein 2
Pheromone-binding protein-related protein 3
Pheromone-binding protein-related protein 4
Pheromone-binding protein-related protein 5
TBP-associated factor 30kD subunit alpha
Ubiquitin carboxy-terminal hydrolase L5 ortholog
Catalytic subunit 3B of the oligosaccharyltransferase complex
NADH dehydrogenase (ubiquinone) acyl carrier protein
NADH ubiquinone oxidoreductase acyl carrier protein
NADH-ubiquinone oxidoreductase acyl carrier protein
NADH-ubiquinone oxidoreductase acyl-carrier subunit
NADH:ubiquinone oxidoreductase Acyl carrier
mitochondrial acyl carrier protein of electron transport complex I
NADH dehydrogenase (ubiquinone) SGDH subunit
NADH-ubiquinone oxidoreductase SGDH subunit
NADH:ubiquinone oxidoreductase SGDH subunit
Sequence-specific single-strand DNA-binding protein
Sequence-specific single-stranded DNA-binding protein
Signal recognition particle receptor beta
Drosophila myocyte-specific enhancer factor 2
Mst57dc for male accessory gland protein
Ribonucleoside diphosphate reductase M1 subunit
Ribonucleoside diphosphate reductase large subunit
ribonucleoside-diphosphate reductase large subunit
Ribonucleoside diphosphate reductase small subunit
ribonucleoside-diphosphate reductase small subunit
Cofilin/actin depolymerizing factor-like
cofilin/actin depolymerizing factor homolog
DNA polymerase alpha 46,000 gamma subunit
DNA polymerase alpha 50 kda primase subunit
DNA polymerase alpha 50,000 gamma subunit
glutathione-dependent formaldehyde dehydrogenase
protein phosphatase from PCR fragment D33
transfer RNA:Histidine-GTG 2-1 pseudogene
transfer RNA:initiator Methionine-CAT 2-1
transfer RNA:initiator Methionine-CAT 1-4
transfer RNA:initiator Methionine-CAT 1-5
gamma-TriMethylAminoButyrAldehyde DeHydrogenase
γ-TriMethylAminoButyrAldehyde DeHydrogenase
Related to angiotensin converting enzyme
70 kDa heat shock protein, cytosolic A 1
70 kDa heat shock protein, cytosolic A 2
70 kDa heat shock protein, cytosolic A 3
70 kDa heat shock protein, cytosolic A 4
70 kDa heat shock protein, cytosolic A 6
N-methyl-D-aspartate receptor-associated protein
mitochondrial Cytochrome c oxidase subunit I
mitochondrial cytochrome oxidase C (subunit I)
mitochondrial Cytochrome c oxidase subunit II
mitochondrial Cytochrome c oxidase subunit III
Mitochondrial NADH-ubiquinone oxidoreductase chain 1
mitochondrial NADH-ubiquinone oxidoreductase chain 2
Mitochondrial NADH-ubiquinone oxidoreductase chain 3
mitochondrial NADH-ubiquinone oxidoreductase chain 4L
Mitochondrial NADH-ubiquinone oxidoreductase chain 5
NADH-ubiquinone oxidoreductase chain subunit 5
NADH-ubiquinone oxidoreductase subunit 5
mitochondrial NADH-ubiquinone oxidoreductase chain 6
mitochondrial transfer RNA:Aspartic acid-GTC
mitochondrial transfer RNA:Glutamic acid-TTC
mitochondrial transfer RNA:Phenylalanine-GAA
mitochondrial transfer RNA:Histidine-GTG
mitochondrial transfer RNA:Isoleucine-GAT
mitochondrial transfer RNA:Methionine-CAT
mitochondrial transfer RNA:Asparagine-GTT
mitochondrial transfer RNA:Glutamine-TTG
mitochondrial transfer RNA:Threonine-TGT
mitochondrial transfer RNA:Tryptophan-TCA
Calcium/calmodulin-dependent protein kinase
maternal effect syncytial blastoderm arrest C
Deformed epidermal autoregulatory factor-1
Succinate dehydrogenase Iron-sulfur protein
Succinate dehydrogenase [ubiquinone] iron-sulfur protein
Succinate dehydrogenase, subunit B (iron-sulfur)
iron-sulfur protein subunit of succinate dehydrogenase
succinate dehydrogenase complex subunit B
Tyrosine kinase with Ig and epidermal growth factor homology domain
UDP-glucose-glycoprotein glucosyltransferase
UDP-glucose:glycoprotein glucosyltransferase
Calcineurin suppressor, chromosome 3, group 3
beta subunit of type I geranylgeranyl transferase
β subunit of type I geranylgeranyl transferase
chaperonin-containing t-complex protein-1 gamma subunit like
chaperonin-containing t-complex protein-1 γ subunit like
Eukaryotic translation initiation factor 4E
eukaryotic translation initiation factor 4E1
60-kDa heat shock protein, mitochondrial
Death-associated inhibitor of apoptosis 2
Drosophila melanogaster inhibitor of apoptosis 2
54 kda mu particle subunit of 26S protease
Src homology 2 ankyrin repeat tyrosine kinase
Src homology 2, ankyrin repeat, tyrosine kinase
Src homology2, ankyrin repeat, tyrosine kinase
Signal recognition particle 19 kD protein
regulatory subunit of protein kinase CK2
nicotinic Acetylcholine Receptor alpha 7E
defective in the avoidance of repellents
Boundary Element Associated Factor of 32
Boundary element-associated factor of 32kD
Calcineurin suppressor, chromosome 2, group 1
NADPH--ferrihemoprotein reductase; NADPH-cytochrome P450 reductase
UDP-glycosyltransferase family 36 member A1
DNA replication-related element binding factor
DNA replication-related element-binding factor
DRE (DNA replication-related element) binding factor
replication-related element-binding factor
adipocyte plasma-membrane-associated protein
platelet-activating factor acetylhydrolase Ib beta-subunit homolog
platelet-activating factor acetylhydrolase Ib β-subunit homolog
Engrailed nuclear homeoprotein-regulated gene
Drosophila Rhythmically expressed gene 5
Drosophila rho-type guanine exchange factor
Rho-type guanine nucleotide exchange factor
Sterol carrier protein X-related thiolase
eukaryotic translation initiation factor 3 subunit i
Calcium/calmodulin-dependent protein kinase I
Protein tyrosine phosphatase-ERK/Enhancer of Ras1
protein tyrosine phosphatase- ERK/enhancer of RAS
Glycoprotein A2/Glycoprotein B5 receptor
Leu-rich repeats-containing G protein-coupled receptor
Leucine-rich repeat-containing G protein-coupled receptor 1
Na[+]-dependent inorganic phosphate cotransporter
ATP synthase oligomycin sensitivity conferral protein
ATP synthase, oligomycin sensitivity conferring protein
OLIGOMYCIN SENSITIVITY CONFERRING PROTEIN
Oligomycin sensitivity-conferring protein
oligomycin sensitivity conferring protein precursor
Galactosyltransferase-associated kinase-like
Drosophila Rhythmically expressed gene 2
Signal-transducer and activator of transcription protein
Signal-transducer and activator of transcription protein at 92E
signal transducer and activator of transcription
signal transducers and activator of transcription
Dual specificity tyrosine phosphorylation-regulated kinase
Dual-specificity tyrosine phosphorylation-regulated kinase 2
small ribonucleoprotein particle U1 subunit 70K
phosphatidylinositol 4-phosphate 5-kinase
type I phosphatidylinositol 4-phosphate 5-kinase
U2 small nuclear riboprotein auxiliary factor 38
Proteasome alpha 4 subunit, Testis-specific 2
Proteasome alpha4 subunit, Testis-specific 2
Proteasome α4 subunit, Testis-specific 2
NADH dehydrogenase (ubiquinone) 75 kDa subunit
NADH-ubiquinone oxidoreductase 75 kDa subunit
NADH:ubiquinone oxidoreductase 75 kDa subunit
NADH:ubiquinone reductase 75 kDa subunit
NADH:ubiquinone reductase 75-kD subunit precursor
NADH:ubiquinone reductase 75kD subunit precursor
NADH dehydrogenase (ubiquinone) 23 kDa subunit
NADH-UBIQUINONE OXIDOREDUCTASE 23 KDA SUBUNIT
NADH: UBIQUINONE REDUCTASE 23 KD SUBUNIT PRECURSOR
NADH:ubiquinone oxidoreductase 23 kDa subunit
NADH:ubiquinone reductase 23kD subunit precursor
cytochrome c oxidase subunit Va preprotein
Smg5 nonsense mediated mRNA decay factor
Positive transcription elongation factor b
Positive transcription elongation factor b, small subunit
NADH dehydrogenase (ubiquinone) 42 kDa subunit
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10
NADH-ubiquinone oxidoreductase 42 kDa subunit
NADH: UBIQUINONE REDUCTASE 42 KD SUBUNIT PRECURSOR
NADH:ubiquinone oxidoreductase 42 kDa subunit
NADH:ubiquinone reductase 42kD subunit precursor
general control nonderepressing 2 kinase
catalytic core of F1 ATP synthase of complex V
Transmembrane O-mannosyltransferase targeting cadherins 3
Transmembrane and tetratricopeptide repeat containing 3
death-related ced-3/neural precursor cell expressed developmentally downregulated 2 (NEDD2)-like protein
Drosophila neurospecific receptor kinase
Guanine nucleotide-binding protein beta-subunit like protein
Guanine nucleotide-binding protein β-subunit like protein
Receptor of activated protein kinase C 1
receptor for activated protein kinase C1
Related to the N terminus of tre oncogene
Protein kinase related to protein kinase N
Phosphofurin acidic cluster sorting protein
ADP-ribosylation factor GTPase activating protein 1
eukaryotic translation initiation factor 4B
Sprouty-related protein with EVH-1 domain
Ca2+-sensing low molecular weight GTPase
17-beta-hydroxysteroid dehydrogenase 10 ortholog
17-β-hydroxysteroid dehydrogenase 10 ortholog
Rieske iron- sulfur protein of complex III
Ubiquinol-cytochrome C reductase iron-sulfur subunit
Ubiquinol-cytochrome c oxidoreductase Iron-sulfur
Ubiquinol-cytochrome c reductase Rieske iron sulfur protein
NADH dehydrogenase (ubiquinone) PDSW subunit
NADH-ubiquinone oxidoreductase PDSW subunit
NADH:ubiquinone oxidoreductase PDSW subunit
Eukaryotic initiation factor 3 p40 subunit
eukaryotic translation initiation factor 3 subunit h
Mitochondrial glycerol-3-phosphate dehydrogenase
Protein kinase, cAMP-dependent, regulatory subunit type 2
gonad-specific amiloride-sensitive sodium channel 1
Small ribonucleoprotein particle protein SmD3
AMP-activated protein kinase alpha subunit
adenosine monophosphate-activated protein kinase
Rho guanine nucleotide exchange factor 2
eukaryotic translation initiation factor 4G
eukaryotic translation initiation factor 4G1
Oculocerebrorenal syndrome of Lowe ortholog
ER degradation enhancer, mannosidase alpha-like 1
eukaryotic translation initiation factor 2B subunit epsilon
Phosphatidylinositol glycan anchor biosynthesis class K
putative inorganic phosphate cotransporter
mitochondrial translation elongation factor Tu 1
Cleavage and polyadenylation specificity factor 160
Drosophila cleavage and polyadenylation stimulation factor-160
cleavage and polyadenylation specificity factor
DNA fragmentation factor-related protein 1
octopamine-activated G-protein-coupled receptor
Nitrilase and fragile histidine triad fusion protein
Glutamate-gated chloride channel subunit alpha
L(3)mbt interactor in ovarian somatic cells
D.melanogaster nucleotide sugar transporter
eukaryotic translation initiation factor 2B subunit beta
Mitochondrial trifunctional protein beta subunit
Mitochondrial trifunctional protein β subunit
Resistance to Insecticide on chromosome 2
Cellular Repressor of E1A-stimulated Genes
eukaryotic translation initiation factor 3 subunit e
gonadotrophin-releasing hormone receptor
methyltransferase 1, tRNA methylguanosine
Dishevelled Associated Activator of Morphogenesis
Major Facilitator Superfamily Transporter 18
scavenger receptor acting in neural tissue and majority of rhodopsin is absent
serine-arginine (SR) protein kinase at location 79D
plexin and met-hepatocyte growth factor receptor-like
Platelet-activating factor acetylhydrolase alpha
platelet-activating factor acetylhydrolase Ib alpha-subunit homolog
platelet-activating factor acetylhydrolase Ib α-subunit homolog
platelet-activating factor acetylhydrolase alpha subunit homolog
Microsomal glutathione S-transferase-like
NADH dehydrogenase (ubiquinone) B14.5 A subunit
NADH-ubiquinone oxidoreductase subunit B14.5a
NADH:ubiquinone oxidoreductase B14.5A subunit
Calmodulin-binding protein related to a Rab3 GDP-GTP exchange protein
Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein
Multiple inositol polyphosphate phosphatase 2
Multiple inositol polyphosphate phosphatase 1
NOP2-Sun domain family, member 2 ortholog
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
eukaryotic translation initiation factor 1A
eukaryotic translation initiation factor 5B
TATA binding protein associated factor 3
UDP-glycosyltransferase family 35 member B1
UDP-glycosyltransferase family 35 member A1
Transforming growth factor beta-activated kinase
transforming growth factor-beta activated kinase 1
transforming growth factor-beta-activated kinase 1
transforming growth factor-β activated kinase 1
transforming growth factor-β-activated kinase 1
Ral guanine nucleotide dissociation stimulator-like
Ral guanine nucleotide dissociation stimulator-like ortholog
Ral guanine nucleotide exchange factor 2
phosphatidylinositol (3,4,5)-trisphosphate phosphatase
Nuclear inhibitor of Protein phosphatase 1
Mitochondrial phosphate carrier protein 2
mitochondrial proton/phosphate symporter
sodium-dependent excitatory amino acid transporter 2
sodium-dependent excitatory amino acid transporter 1
BM-40-secreted protein acidic and rich in cysteine
Adenomatous polyposis coli tumor suppressor homolog 2
D. melanogaster transforming acidic coiled coil
Drosophila Transforming Acidic Coiled-Coil protein
Drosophila transforming acidic coiled-coil
1-Acylglycerol-3-phosphate O-acyltransferase 2
UDP-glycosyltransferase family 37 member C1
UDP-glycosyltransferase family 37 member B1
UDP-glycosyltransferase family 37 member A1
mismatch-specific uracil DNA glycosylase
STIP1 homology and U-box containing protein 1
UDP-glycosyltransferase family 36 member E1
UDP-glycosyltransferase family 49 member B1
UDP-glycosyltransferase family 36 member F1
Methionyl-tRNA synthetase, mitochondrial
Mesencephalic astrocyte-derived neurotrophic factor
Mesencephalic astrocyte-derived neurotrophic factor ortholog
Dual-specificity tyrosine phosphorylation-regulated kinase 3
kinetochore Mis12-Ndc80 network component 1
Isocitrate dehydrogenase (NAD+) 3 catalytic subunit alpha
SET and MYND domain containing, class 4, member 4
Ubiquitin-like domain-containing C-terminal domain phosphatase 1
beta1,4-N-acetylgalactosaminyltransferase A
β1,4-N-acetylgalactosaminyltransferase A
Polypeptide N-Acetylgalactosaminyltransferase 3
Cullin-associated and neddylation-dissociated 1
ubiquitin-like protein-specific protease 1
modifier of rpr and grim, ubiquitously expressed
OXA1L mitochondrial inner membrane protein
Drosophila peptidyl-prolyl cis/trans isomerase-like 4
Peptidyl-prolyl cis/trans isomerase-like 4
eukaryotic translation initiation factor 3 subunit j
ATP-dependent chromatin assembly factor large subunit
ATP-utilizing chromatin assembly and remodeling factor
Hairy and enhancer of split related protein
Leucine-rich pentatricopeptide repeat containing 2
pentatricopeptide repeat containing protein
Drosophila dodeca-satellite-binding protein 1
Cleavage stimulation factor 64 kD subunit
Cleavage stimulation factor 64 kilodalton subunit
Cleavage and polyadenylation specificity factor 100
Pyruvate dehydrogenase E1 alpha subunit 1
Ankyrin repeat and LEM domain containing 2
Kip1 ubiquitination-promoting complex subunit 2
Death executioner caspase related to Apopain/Yama
Drosophila executioner caspase related to Apopain/Yama
Target of methylation-induced silencing 1
DNA fragmentation factor-related protein 4
DNA fragmentation factor-related protein 3
DNA fragmentation factor-related protein 2
solute carrier 7-family amino acid transporter
Mitochondrial trifunctional protein alpha subunit
Mitochondrial trifunctional protein α subunit
Transmembrane O-mannosyltransferase targeting cadherins 2
Drosophila-specific factor against fungal infection
Drosophila-specific factor against fungal infection 1
mitochondrial transcription termination factor
Transmembrane 9 superfamily protein member 4
putative homeodomain transcription factor
leader sequence, collagen-related repetitive motif and a serine/threonine-rich motif
mitochondrial aspartate/glutamate carrier
Drosophila fragile X mental retardation protein
cg 6203 gene product from transcript cg6203-rc
eukaryotic translation elongation factor 1 beta
Juvenile Hormone Acid O-Methyl Transferase
Juvenile Hormone Acid O-Methyltransferase
Juvenile hormone acid methyl transferase
nicotinic Acetylcholine Receptor alpha 34E
testis-specific gamma-tubulin ring protein 91
Kinetochore and EB1 associated basic protein
Rab geranylgeranyltransferase subunit beta
beta subunit of type II geranylgeranyl transferase
β subunit of type II geranylgeranyl transferase
SMAD specific E3 ubiquitin protein ligase
GTP-specific form of the succinyl-CoA synthetase beta subunit
GTP-specific form of the succinyl-CoA synthetase β subunit
Succinyl coenzyme A synthetase GDP-forming beta subunit
Succinyl-coenzyme A synthetase beta subunit, GDP-forming
Succinyl-coenzyme A synthetase β subunit, GDP-forming
eukaryotic translation elongation factor 1 gamma
eukaryotic translation initiation factor 3 subunit g1
Translocase of inner mitochondrial membrane 29
VAMP-associated protein of 33kDa ortholog A
Pyruvate dehydrogenase phosphatase regulatory subunit
Pyruvate dehydrogenase E1 alpha subunit 2
Heparan-alpha-glucosaminide N-acetyltransferase
Regulatory particle non-ATPase 13-related
small conductance calcium-activated potassium channel
ADAM metallopeptidase with thrombospondin type 1 motif B
Regulator of Telomere Elongation Helicase 1
N-acetylneuraminate-9-phosphate phosphatase
Glycosylphosphatidylinositol anchor attachment 1
Glycosylphosphatidylinositol anchor attachment 1 ortholog
beta-hydroxy-Epsilon-N-trimethyllysine aldolase
X-ray repair cross-complementing protein 4
target of rapamycin (TOR)-associated protein
NADH dehydrogenase (ubiquinone) B16.6 subunit
NADH-ubiquinone oxidoreductase B16.6 subunit
NADH:ubiquinone oxidoreductase B16.6 subunit
Mitochondrial assembly regulatory factor
NADH dehydrogenase (ubiquinone) ASHI subunit
NADH-ubiquinone oxidoreductase ASHI subunit
NADH:ubiquinone oxidoreductase ASHI subunit
phosphatase and tensin homolog-induced putative kinase 1
muscarinic Acetylcholine Receptor, C-type
NADH dehydrogenase (ubiquinone) MNLL subunit
NADH-ubiquinone oxidoreductase MNLL subunit
NADH:ubiquinone oxidoreductase MNLL subunit
defective proboscis extension response 14
Dehydrodolichyl diphosphate synthase subunit
Phenylalanyl-tRNA synthetase alpha subunit
Phenylalanyl-tRNA synthetase, alpha-subunit
Phosphatidylinositol glycan anchor biosynthesis class T
Serine Protease Immune Response Integrator
Chromatin assembly factor 1, p180 subunit
Phosphorylase kinase regulatory subunit alpha
phosphorylase kinase regulatory subunit alpha 2
ADP-ribosylation factor related protein 1
Adaptor Protein complex 1, gamma subunit
SET and MYND domain containing, arthropod-specific, member 9
Golgi-localised, gamma-ear containing, ADP ribosylation factor-binding
Golgi-localised, γ-ear containing, ADP ribosylation factor-binding
Golgi-localized, gamma-adaptin ear containing, ARF binding protein
Golgi-localized, γ-adaptin ear containing, ARF binding protein
Protein phosphatase 4 regulatory subunit 2-related protein
SET and MYND domain containing, arthropod-specific, member 4
Transmembrane BAX inhibitor motif containing 5
GTPase activating protein and VPS9 domains 1
NADH:ubiquinone oxidoreductase subunit V3
Peptidoglycan-recognition protein-SA precursor
severe impairment of CI with lengthened youth
Protein interacting with Ttk69 and Sin3A
Apoptosis and caspase activation inhibitor
1-Acylglycerol-3-phosphate O-acyltransferase 1
Flavin adenine dinucleotide synthetase 1
Major Facilitator Superfamily Transporter 10
branched-chain amino acid aminotransferase
Nascent-associated complex beta-subunit-like, testis 1
Nascent-associated complex β-subunit-like, testis 1
beta-subunit of nascent polypeptide-associated complex
β-subunit of nascent polypeptide-associated complex
Nascent-associated complex beta-subunit-like, testis 2
Nascent-associated complex β-subunit-like, testis 2
Nascent-associated complex beta-subunit-like, testis 4
Nascent-associated complex β-subunit-like, testis 4
NADH dehydrogenase (ubiquinone) B18 subunit
NADH-ubiquinone oxidoreductase B18 subunit
NADH:ubiquinone oxidoreductase B18 subunit
Cytochrome c oxidase copper chaperone COX17
Dihydrolipoamide branched chain transacylase E2
ALG14 UDP-N-acetylglucosaminyltransferase subunit
ALG14, UDP-N-acetylglucosaminyltransferase subunit
Inner mitochondrial membrane peptidase subunit 1
Drosophila phosphatidylinositol synthase
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
GTPase regulator associated with focal adhesion kinase ortholog
Suppression Of Retinal Degeneration Disease 1 upon overexpression 1
NADH dehydrogenase (ubiquinone) 20 kDa subunit
NADH-UBIQUINONE OXIDOREDUCTASE 20 KDA SUBUNIT
NADH:ubiquinone oxidoreductase 20 kDa subunit
eukaryotic translation initiation factor 5
defective proboscis extension response 18
peroxisomal Multifunctional enzyme type 2
Ubiquinol-cytochrome C reductase complex 14 kDa protein
Ubiquinol-cytochrome c oxidoreductase 14 kDa
Ubiquinol-cytochrome c reductase 14 kDa protein
Ubiquinol-cytochrome c reductase 14 kDa subunit
Strumpellin and WASH-interacting protein
Nuclear envelope integral membrane protein
NADH dehydrogenase (ubiquinone) 24 kDa subunit
NADH dehydrogenase ubiquinone flavoprotein 2
NADH-ubiquinone oxidoreductase 24 kDa subunit
NADH:ubiquinone oxidoreductase 24 kDa subunit
Polypeptide N-Acetylgalactosaminyltransferase 7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2
UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2
PDGF (platelet-derived growth factor)- and VEGF (vascular endothelial growth factor)-related factor 1
Succinate dehydrogenase, subunit B (iron-sulfur)-like
Heterochromatin Protein 1D3 chromoshadow domain
N(alpha)-acetyltransferase 15/16 auxiliary subunit
NADH dehydrogenase (ubiquinone) 18 kDa subunit
NADH-ubiquinone oxidoreductase 18 kDa subunit
NADH:ubiquinone oxidoreductase 18 kDa subunit
Small nuclear ribonucleoprotein U11/U12 subunit 48
Required for cell differentiation 1 ortholog
tRNA adenosine(37) threonylcarbamoyltransferase, mitochondrial
ATP binding cassette subfamily D member 3
HECT and RLD domain containing protein 2
HECT and RLD domain containing protein 2 ortholog
Catalytic subunit 3A of the oligosaccharyltransferase complex
ATP binding cassette subfamily A member 3
NADH dehydrogenase (ubiquinone) 15 kDa subunit
NADH-ubiquinone oxidoreductase 15 kDa subunit
NADH:ubiquinone oxidoreductase 15 kDa subunit
TBC1 domain family, member 15/17 ortholog
nicotinic acetylcholine receptor beta 21C
uncharacterized nascent polypeptide-associated complex beta subunit
germinal nascent polypeptide-associated complex alpha subunit
Major Facilitator Superfamily Transporter 3
Mitochondrial transcription termination factor 4
Phosphatidylinositol glycan anchor biosynthesis class W a
Drosophila Vesicular Glutamate Transporter
NADH dehydrogenase (ubiquinone) B17.2 subunit
NADH-ubiquinone oxidoreductase subunit B17.2
NADH:ubiquinone oxidoreductase B17.2 subunit
Actin-related protein 2/3 complex, subunit 5
Hepatocyte growth factor regulated tyrosine kinase
Hepatocyte growth factor regulated tyrosine kinase substrate
Hepatocyte growth factor-regulated tyrosine kinase substrate
Hepatocyte growth factor-regulated tyrosine substrate
Hepatocyte growth-factor-regulated substrate
histidine triad nucleotide binding protein 1
alpha1,4-N-acetylgalactosaminyltransferase 1
α1,4-N-acetylgalactosaminyltransferase 1
NADH dehydrogenase (ubiquinone) B14.5 B subunit
NADH-ubiquinone oxidoreductase subunit B14.5b
NADH:ubiquinone oxidoreductase B14.5B subunit
Oligosaccharyltransferase complex subunit C
Polypeptide N-Acetylgalactosaminyltransferase 2
TBP-associated factor 30kD subunit alpha-2
Polypeptide N-Acetylgalactosaminyltransferase 5
NADH dehydrogenase (ubiquinone) 13 kDa A subunit
NADH-ubiquinone oxidoreductase 13 kDa-A subunit
NADH:ubiquinone oxidoreductase 13 kDa A subunit
60 kDa heat shock protein homolog 2 mitochondrial
Inositol phosphatase interacting protein
NADH dehydrogenase (ubiquinone) 51 kDa subunit
NADH-UBIQUINONE OXIDOREDUCTASE 51 KDA SUBUNIT
NADH:ubiquinone oxidoreductase 51 kDa subunit
NADH:ubiquinone oxidoreductase, 51kDa subunit
Testis-Specific Serine/Threonine Kinase 2
Arylalkylamine N-acetyltransferase-like 2
Ring finger and CHY zinc finger domain containing 1
tRNA methyltransferase 6 non-catalytic subunit
Apoptosis antagonizing transcription factor
apoptosis antagonizing transcription factor ortholog
Fibroblast growth factor receptor 1 oncogene partner 2
Fibroblast growth factor receptor 1 oncogene partner 2 ortholog
3-Hydroxymethyl-3-methylglutaryl-CoA lyase
UDP-glycosyltransferase family 307 member A1
PDGF- and VEGF-receptor related factor 2
Homocysteine-induced endoplasmic reticulum protein
Phosphorylase kinase regulatory subunit beta
Post-GPI attachment to proteins 5 ortholog
Vascular endothelial growth factor receptor
Vascular endothelial growth factor receptor-1 like
platelet-derived growth factor/vascular endothelial growth factor receptor
Oligosaccharide transferase gamma subunit
Calcitonin-like diuretic hormone (31 residues)
Phosphatidylinositol glycan anchor biosynthesis class U
Phosphatidylinositol glycan anchor biosynthesis, class U
Phosphatidylinositol glycan anchor biosynthesis, class U ortholog
Organic anion transporting polypeptide 30B
alpha6 nicotinic acetylcholine receptor subunit
nicotinic Acetylcholine Receptor alpha 30D
α6 nicotinic acetylcholine receptor subunit
eukaryotic translation elongation factor 1 delta
eukaryotic translation elongation factor 1delta
eukaryotic translation elongation factor 1δ
Caseinolytic protease proteolytic subunit
Oxidative stress-responsive serine-rich protein 1
defective proboscis extension response 19
Basal body up regulated gene 22 ortholog
endoplasmic reticulum membrane protein complex 3
Ribosome biogenesis protein WDR12 homolog
SAM-motif ubiquitously expressed punctatedly localized protein
Promyelocytic leukemia zinc finger ortholog
Phosphatidylinositol-specific phospholipase C X domain containing
Organic anion transporting polypeptide 33Ea
Organic anion transporting polypeptide 33Eb
Scm-related gene containing four mbt domains
ALG7 dolichyl-phosphate N-acetylglucosaminephosphotransferase
ER degradation enhancer, mannosidase alpha-like 2
Phosphoethanolamine cytidylyltransferase
phosphoethanolamine cytidylyltransferase;
mitochondrial translation release factor 1
Proteasome alpha6 subunit, Testis-specific
Ultraviolet (UV) radiation resistance-associated gene
NADH dehydrogenase (ubiquinone) B22 subunit
NADH-ubiquinone oxidoreductase B22 subunit
NADH:ubiquinone oxidoreductase B22 subunit
StAR related lipid transfer domain containing 7
Flavin adenine dinucleotide synthetase 2
Transient receptor potential cation channel gamma
Transient receptor potential cation channel γ
NUBP iron-sulfur cluster assembly factor 1
Bub3 interacting GLEBS and Zinc finger domain protein
Leucine-rich-repeats and calponin homology domain protein
small glutamine-rich tetratricopeptide containing protein
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
mitochondrial translation elongation factor Ts
Drosophila nuclear transport factor-2-related
UDP-glycosyltransferase family 301 member D1
UDP-glycosyltransferase family 36 member D1
neural precursor cell-expressed developmentally downregulated
Betaine-homocysteine S-methyltransferase
endoplasmic reticulum membrane protein complex 5
PH domain leucine-rich repeat protein phosphatase
Dolichyl-phosphate mannosyltransferase subunit 1
Arylalkylamine N-acetyltransferase-like 3
Pyridine nucleotide-disulfide oxidoreductase domain 1
Actin-related protein 2/3 complex, subunit 2
Transmembrane 9 superfamily protein member 2
Sensitized chromosome inheritance modifier 19
Chromatin-linked adaptor for MSL proteins
NUBP iron-sulfur cluster assembly factor, mitochondrial
CCR4-NOT transcription complex subunit 3
SET and MYND domain containing, arthropod-specific, member 5
eukaryotic translation initiation factor 3 subunit f2
Post-GPI attachment to proteins 3 ortholog
Zinc/iron regulated transporter-related protein 1
Zinc/iron regulated transporter-related protein 42C.1
Zinc/iron regulated transporter-related protein 42C.2
Growth arrest and DNA damage-inducible 45
growth arrest and DNA damage-inducible gene 45
Drosophila Down syndrome cell adhesion molecule
Drosophila Down syndrome cell adhesion molecule 1
mitochondrial translation elongation factor Tu 2
Phosphatidylinositol glycan anchor biosynthesis class G
Death Resistor Adh domain containing Target
Major Facilitator Superfamily Transporter 12
Mitochondrial processing peptidase subunit alpha
Calcium-independent receptor for alpha-latrotoxin
Calcium-independent receptor for α-latrotoxin
Peptidoglycan-recognition protein-SC1b precursor
aaRS-interacting multifunctional protein 1
aminoacyl-tRNA synthetase-interacting multifunctional protein 1
Poly(A)-binding protein-dependent poly(A) ribonuclease 2
Fanconi anemia complementation group I homologue
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
Outer dynein arm dynein axonemal light chain 1
protein of relevant evolutionary and lymphoid interest-like
SET and MYND domain containing, class 4, member 1
Mitochondrial amidoxime reducing component
Phosphatidylinositol glycan anchor biosynthesis class N
Eiger, tumour necrosis factor family member
Chondroitin sulfate N-acetylgalactosaminyltransferase
Chromatin assembly factor 1, p105 subunit
G protein-coupled receptor kinase interacting ArfGAP
G-protein-coupled receptor kinase-interacting protein
Methyl methanesulfonate sensitivity 4 ortholog
NADH dehydrogenase (ubiquinone) B14 subunit
NADH-ubiquinone oxidoreductase B14 subunit
NADH:ubiquinone oxidoreductase B14 subunit
SET and MYND domain containing, class 4, member 3
Death Associated Molecule related to Mch2
Death associated molecule related to Mch2 caspase
Zinc/iron regulated transporter-related protein 48C
U5 small nuclear ribonucleoprotein-specific factor
mitochondrial translation initiation factor 3
Squamous cell carcinoma-related oncogene 3
Squamous cell carcinoma-related oncogene 3 ortholog
Scaffold protein containing ankyrin repeats and SAM domain
Enoyl-[acyl-carrier-protein] reductase, mitochondrial
Mitochondrial trans-2-enoyl-CoA reductase
trans-2-enoyl-CoA reductase, mitochondrial
Cysteinyl-tRNA synthetase, mitochondrial
eukaryotic translation initiation factor 3 subunit m
SET and MYND domain containing, arthropod-specific, member 1
Activity-regulated cytoskeleton associated protein 1
Activity-regulated cytoskeleton associated protein 2
Stress-activated protein kinase [SAPK]-interacting protein
stress-activated map kinase-interacting protein 1
Adenosine deaminase-related growth factor E
NADH dehydrogenase (ubiquinone) B15 subunit
NADH-ubiquinone oxidoreductase B15 subunit
NADH:ubiquinone oxidoreductase B15 subunit
NADH dehydrogenase (ubiquinone) 51 kDa subunit-like 2
Polypeptide N-Acetylgalactosaminyltransferase 1
eukaryotic translation initiation factor 2B subunit gamma
Ubiquitin-fold modifier conjugating enzyme 1
endoplasmic reticulum membrane protein complex 7
Boundary element-associated factor of 75 kD
Poly(ADP-ribose) polymerase family member 16
Ral GEF with PH domain and SH3 binding motif
Glyceraldehyde 3 phosphate dehydrogenase 3
Asparaginyl-tRNA synthetase, mitochondrial
Eps15 homology domain containing protein-binding protein 1
Poly(A) binding protein interacting protein 1
SET and MYND domain containing, arthropod-specific, member 7
SET and MYND domain containing, arthropod-specific, member 6
General transcription factor IIIC subunit 3
Methylthioadenosine phosphorylase ortholog
eukaryotic translation initiation factor 3 subunit b
Ubiquinol-cytochrome C reductase complex 6.4 kDa protein
Ubiquinol-cytochrome c oxidoreductase 6.4 kDa
Ubiquinol-cytochrome c reductase 6.4 kDa protein
Ubiquinol-cytochrome c reductase 6.4 kDa subunit
NADH dehydrogenase (ubiquinone) 51 kDa subunit-like 1
eukaryotic translation initiation factor 3 subunit c
Phosphatidylinositol glycan anchor biosynthesis class A
Oligosaccharide transferase Delta subunit
defective proboscis extension response 13
Phosphatidylinositol glycan anchor biosynthesis class O
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
predicted phosphoenolpyruvate carboxykinase
methyl-branched cuticular hydrocarbon elongase
Multiple C2 domain and transmembrane region protein
Major Facilitator Superfamily Transporter 15
testis-specifically expressed bromodomain containing protein-2
Arylalkylamine N-acetyltransferase-like 5
Arylalkylamine N-acetyltransferase-like 6
Arylalkylamine N-acetyltransferase-like 4
Thioredoxin related transmembrane protein 2
Mitochondrial phosphate carrier protein 1
Gram-negative binding protein-like protein
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1
Mannosyl (α-1,3-)-glycoprotein β-1,2-N-acetylglucosaminyltransferase
Mannosyl (α-1,3-)-glycoprotein β-1,2-N-acetylglucosaminyltransferase 1
UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I
UDP-GlcNAc:a-3-D-mannoside-β-1,2-N-acetylglucosaminyltransferase I
Inner mitochondrial membrane peptidase subunit 2
DNA methyltransferase 1 associated protein 1
Calcium and integrin binding family member 2
NADH dehydrogenase (ubiquinone) B14.7 subunit
Leucine-rich repeat activity-regulated protein at synapses
UDP-glycosyltransferase family 49 member C1
Ankyrin-repeat, SH3-domain and Proline-rich-region containing Protein
Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein
Major Facilitator Superfamily Transporter 16
amylo-alpha-1,6-glucosidase, 4-alpha-glucanotransferase
amylo-α-1,6-glucosidase, 4-α-glucanotransferase
eukaryotic translation elongation factor, selenocysteine-specific
TATA box-binding protein-associated factor RNA polymerase I subunit C-like
NADH dehydrogenase (ubiquinone) B12 subunit
NADH-ubiquinone oxidoreductase B12 subunit
NADH:ubiquinone oxidoreductase B12 subunit
PGRP-LC-interacting inhibitor of Imd signaling
Phosphatidylinositol glycan anchor biosynthesis class M
eukaryotic translation initiation factor 3 subunit k
Pleckstrin homology and RUN domain containing M1
Organic anion transporting polypeptide 58Db
Organic anion transporting polypeptide 58Dc
SPG11 vesicle trafficking associated, spatacsin
Phosphatidylinositol 4-phosphate 5-kinase 59B
Phosphatidylinositol 4-phosphate 5-kinase at 59B
endoplasmic reticulum membrane protein complex 8/9
CCHC-type zinc finger nucleic acid binding protein
eukaryotic translation initiation factor 2B subunit delta
eukaryotic translation initiation factor 6
NADH:ubiquinone oxidoreductase complex assembly factor 3
Growth arrest and DNA-damage-inducible 34
Protein phosphatase 1 regulatory subunit 15
CCR4-NOT transcription complex subunit 11
Mitochondrial INner membrane Organizing System 1
N(alpha)-acetyltransferase 35 auxiliary subunit
unconventional prefoldin RPB5 interactor
RNApolymerase II carboxyl-terminal domain phosphatase
S-adenosylmethionine sensor upstream of TORC1
S-adenosylmethionine sensor upstream of mTORC1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
NADH dehydrogenase (ubiquinone) 19 kDa subunit
NADH-UBIQUINONE OXIDOREDUCTASE 19 KDA SUBUNIT
NADH:ubiquinone oxidoreductase 19 kDa subunit
Epidermal growth factor receptor pathway substrate clone 15
Thiamine pyrophosphate carrier protein 2
Juvenile hormone esterase binding protein 29
mitochondrial ribosomal protein large subunit 17
Homeodomain-interacting protein kinase 2
Protein phosphatase Mg2+/Mn2+ dependent 1
defective proboscis extension response 20
HECT and RLD domain containing E3 ligase
HECT and RLD domain containing E3 ubiquitin ligase 4
SUMO-related HECT domain and RCC repeat protein for Toll pathway activation
CTP:phosphocholine cytidylyltransferase 2
TOX high mobility group box family member 4
ATP binding cassette subfamily B member 7
Phosphatidylinositol glycan anchor biosynthesis class W b
Polypeptide N-Acetylgalactosaminyltransferase 6
Poly(A) specific ribonuclease subunit PAN3
eukaryotic translation initiation factor 1
Phosphatidylinositol glycan anchor biosynthesis class C
Phosphatidylinositol glycan anchor biosynthesis, class C
Phosphatidylinositol glycan anchor biosynthesis, class C ortholog
Glutathione peroxidase homolog with thioredoxin peroxidase activity
PHGPx with glutathione peroxidase activity
phospholipid hydroperoxide glutathione peroxidase
Phosphatidylinositol glycan anchor biosynthesis class B
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Mitochondrial E3 ubiquitin protein ligase 1
Mitochondrial E3 ubiquitin protein ligase 1 homologue
Tumor protein p53 inducible nuclear protein
Guanine nucleotide exchange factor GEF64C
Rho guanine nucleotide exchange factor at 64C
Fat storage inducing transmembrane protein
tRNA adenosine(37) threonylcarbamoyltransferase complex, ATPase subunit type 2
Cytochrome c1, heme protein, mitochondrial
Ubiquinol-cytochrome c oxidoreductase Cytochrome C1
Ubiquinol-cytochrome c reductase Cytochrome C1, heme protein
Transmembrane 9 superfamily protein member 3
4'-phosphopantetheine adenylyltransferase - dephospho-CoA kinase
Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase
eukaryotic translation initiation factor 4E4
Ubiquinol-cytochrome c reductase complex assembly factor 1
Rho guanine nucleotide exchange factor 4
testis-specific gamma-tubulin ring protein 84
Peptidoglycan-recognition protein-SD precursor
Probable medium-chain specific acyl-CoA dehydrogenase, mitochondrial
medium-chain acyl-coenzyme A dehydrogenase
eukaryotic translation initiation factor 4E5
Cleavage and polyadenylation specific factor 6
GTPase activating protein and centrosome-associated
GTPase activating protein and centrosome-associated ortholog
GTPase activating protein, SECIS-dependent read-through
Z band alternatively spliced PDZ-motif protein 66
Transient receptor potential cation channel
Transient receptor potential cation channel A1
Transient receptor potential cation channel A1 ortholog
cytochrome c oxidase assembly factor COX18
uridine diphosphate-glucose pyrophosphorylase
mitochondrial ribosome recycling factor 1
Metallophosphoesterase domain containing
Z band alternatively spliced PDZ-motif protein 67
calcium-independent phospholipase A2 VIA
CTD nuclear envelope phosphatase 1 regulatory subunit 2
Ankyrin repeat and MYND domain containing 2
Ankyrin repeat and MYND domain-containing protein 2
Biogenesis of lysosome-related organelles complex 1, subunit 4
Biogenesis of lysosome-related organelles complex 1, subunit 2
fork head transcription factor long isoform
fork head transcription factor short isoform
Coiled-coil domain containing protein 151
Succinate dehydrogenase Flavoprotein subunit
Succinate dehydrogenase [ubiquinone] flavoprotein subunit
Succinate dehydrogenase, subunit A (flavoprotein)-like
Regulatory particle triple-A ATPase 4-related
eukaryotic translation initiation factor 3 subunit l
SET and MYND domain containing, class 4, member 2
Isoprenylcysteine carboxyl methyltransferase
isoprenylcysteine carboxylmethyltransferase
Tondu-domain-containing Growth Inhibitor
Boundary element-associated factor of 25 kD
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase a
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase b
Zinc/iron regulated transporter-related protein 71B
Reversion-inducing-cysteine-rich protein with kazal motifs
Regulatory particle non-ATPase 12-related
Squamous cell carcinoma-related oncogene
Squamous cell carcinoma-related oncogene ortholog
aaRS-interacting multifunctional protein 2
aminoacyl-tRNA synthetase-interacting multifunctional protein 2
Polypeptide N-Acetylgalactosaminyltransferase 8
Isoleucyl-tRNA synthetase, mitochondrial
Thioredoxin-related transmembrane protein 3
1-Acylglycerol-3-phosphate O-acyltransferase 4
1-Acylglycerol-3-phosphate O-acyltransferase 3
AFG3 like matrix AAA peptidase subunit 2
NADH dehydrogenase (ubiquinone) 24 kDa subunit-like
Ubiquinol-cytochrome C reductase complex ubiquinone-binding protein QP-C
Ubiquinol-cytochrome c oxidoreductase Ubiquinone-binding protein QP-C
Ubiquinol-cytochrome c reductase Ubiquinone-binding protein QP-C
Ubiquinol-cytochrome c reductase ubiquinone-binding protein
Organic anion transporting polypeptide 74D
U4-U6 small nuclear riboprotein factor 60K
CREB-regulated transcription coactivator
Adenosine deaminase-related growth factor B
Adenosine deaminase-related growth factor A
Tryptophanyl-tRNA synthetase, mitochondrial
Myosin phosphatase targeting subunit 75D
Nuclear Fragile-X Mental Retardation Protein-interacting Protein
SET and MYND domain containing, arthropod-specific, member 2
UDP-glycosyltransferase family 316 member A1
Mitogen-activated protein kinase phosphatase 3
Aldehyde dehydrogenase 7 family member A1
Phosphatidylinositol glycan anchor biosynthesis class F
Gamma-aminobutyric acid transaminase isoform A
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Squamous cell carcinoma-related oncogene 4
Squamous cell carcinoma-related oncogene 4 ortholog
L-threonine 3-dehydrogenase, mitochondrial
NADH dehydrogenase (ubiquinone) 39 kDa subunit
NADH-ubiquinone oxidoreductase 39 kDa subunit
NADH:ubiquinone oxidoreductase 39 kDa subunit
mitochondrial transcription termination factor 3
NUBP iron-sulfur cluster assembly factor 2
Distal membrane arm assembly component 2
Phosphorylated C-terminal domain (CTD)-interacting Factor 1
Decaprenyl diphosphate synthase subunit 2
Polyprenyl diphosphate synthase subunit 2
subtilisin kexin isozyme-1/site-1 protease
Amyotrophic lateral sclerosis 2 ortholog
eukaryotic translation initiation factor 2A
delta-1-Pyrroline-5-carboxylate dehydrogenase 1
delta-1-pyrroline-5-carboxylate dehydrogenase
Delta[1]-pyrroline-5-carboxylate synthase
NADH dehydrogenase (ubiquinone) B14.5 A subunit-like
ADP-ribosylation factor GTPase activating protein 3
endoplasmic reticulum membrane protein complex 4
Suppressor of Stem-Loop mutation ortholog
peroxisome proliferator-activated receptor gamma coactivator 1
peroxisome proliferator-activated receptor gamma coactivator-1alpha
peroxisome proliferator-activated receptor γ coactivator 1
eukaryotic translation initiation factor 3 subunit a
Factor interacting with poly(A) polymerase 1
eukaryotic translation initiation factor 3 subunit f1
Coiled-coil domain containing protein 39
Rab geranylgeranyltransferase subunit alpha
defective proboscis extension response 16
protein kinase RNA-like endoplasmic reticulum kinase
Polymerase (DNA-directed), delta interacting protein 2
Mitochondrial morphology and cristae structure 1
endoplasmic reticulum membrane protein complex 1
Phosphatidylinositol glycan anchor biosynthesis class H
Drosophila melanogaster PSE-binding protein 95-kDa subunit
muscarinic Acetylcholine Receptor, B-type
GTPase indispensable for equal segregation of chromosomes
novel GTPase indispensable for equal segregation of chromosomes
eukaryotic translation initiation factor 4AIII
SRA stem-loop interacting RNA binding protein 2
ATP-specific form of the succinyl-CoA synthetase beta subunit
ATP-specific form of the succinyl-CoA synthetase β subunit
Succinyl-coenzyme A synthetase beta subunit, ADP-forming
Succinyl-coenzyme A synthetase β subunit, ADP-forming
JmjC domain-containing histone demethylase 1
ATPase H+ transporting accessory protein 2
Drosophila homologue of prorenin receptor
Vacuolar H[+] ATPase M8.9 accessory subunit
TWIK-related acid-sensitive K[+] channel 7
JmjC domain-containing histone demethylase 2
Branched chain keto acid dehydrogenase E1 subunit alpha
branched-chain a-keto acid dehydrogenase
Regulatory particle triple-A ATPase 3-related
alpha-2-macroglobulin receptor-associated protein
α-2-macroglobulin receptor-associated protein
Coactivator Arg methyltransferase for Ecr/Usp
NADH:ubiquinone oxidoreductase complex assembly factor 4
TATA box-binding protein-associated factor RNA polymerase I subunit B
Phytanoyl-CoA dioxygenase domain containing 1
Thiamine pyrophosphate carrier protein 1
Succinate dehydrogenase Cytochrome B560 subunit
Translationally Controlled Tumor Protein
Translationally controlled tumor protein ortholog
GRIP and coiled-coil domain containing 88 kDa
Dihydrolipoyllysine-residue succinyltransferase
Peptidoglycan-recognition protein-LB precursor
defective proboscis extension response 5
Dynein axonemal light intermediate chain 1
GRIP and coiled-coil domain containing 185 kDa
defective proboscis extension response 15
eukaryotic translation initiation factor 3 subunit d2
N-acetylneuraminic acid phosphate synthase
UDP-glycosyltransferase family 37 member A2
UDP-glycosyltransferase family 37 member A3
PolyA-binding protein interacting protein 2
Cilia and flagella associated protein 299
Gamma-interferon-inducible lysosomal thiol reductase
Gamma-interferon-inducible lysosomal thiol reductase 1
TWIK-related acid-sensitive K[+] channel 6
Adenosine deaminase-related growth factor A2
Adenosine deaminase-related growth factor D
Adenosine deaminase-related growth factor C
Forkhead bOX-containing protein, subfamily O
forkhead box-containing protein, O subfamily
Mitochondrial processing peptidase beta subunit
Ubiquinol-cytochrome C reductase complex core protein I
Ubiquinol-cytochrome c oxidoreductase Core protein 1
Ubiquinol-cytochrome c reductase Core protein 1
defective proboscis extension response 9
Kip1 ubiquitination-promoting complex subunit 1
Spermidine/spermine N1-acetyltransferase
Spermidine/spermine-N1 acetyltransferase
Zinc/iron regulated transporter-related protein 88E
specifically, Rac-1 associated protein 1
Transmembrane O-mannosyltransferase targeting cadherins 4
Cerebral cavernous malformation 3 ortholog
Actin-related protein 2/3 complex, subunit 3A
Drosophila melanogaster PSE-binding protein 45-kDa subunit
Zinc/iron regulated transporter-related protein 3
Zinc/iron regulated transporter-related protein 89B
Succinate dehydrogenase assembly factor 3
Coiled-coil domain containing protein 114
ADP-ribosylation factor-like 6 interacting protein 1
endoplasmic reticulum membrane protein complex 2B
endoplasmic reticulum membrane protein complex 2A
Single-strand-selective monofunctional uracil-DNA glycosylase
single-strand-specific monofunctional uracil-DNA glycosylase 1
Pyrroline-5-carboxylate reductase-like 2
adenosine 3'-phosphate 5'-phosphosulfate transporter
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
mitochondrial transcription termination factor 5
alpha2-adrenergic-like octopamine receptor
Succinyl-coenzyme A synthetase alpha subunit 2
Succinyl-coenzyme A synthetase α subunit 2
Phosphatidylinositol glycan anchor biosynthesis class L
eukaryotic translation initiation factor 3 subunit g2
Major Facilitator Superfamily Transporter 9
Kainate-type ionotropic glutamate receptor subunit 1D
UDP-glycosyltransferase family 49 member B2
female sterile independent of transformer
female-specific independent of transformer
Isocitrate dehydrogenase (NAD+) 3 non-catalytic subunit beta
prolonged depolarization afterpotential (PDA) is not apparent
Phosphatidylethanolamine-binding protein 1
testis-enriched HMG-box-containing protein 1
testis-enriched HMG-box-containing protein-1
testis-enriched HMG-box-containing protein 2
testis-enriched HMG-box-containing protein-2
Ubiquitin-specific protease 12/46 ortholog
p53-like regulator of apoptosis and cell cycle
UDP-glycosyltransferase family 303 member B3
UDP-glycosyltransferase family 303 member B1
UDP-glycosyltransferase family 303 member B2
Gamma-interferon-inducible lysosomal thiol reductase 3
Gamma-interferon-inducible lysosomal thiol reductase 2
Protein tyrosine phosphatase, mitochondrial 1
SUCCINATE DEHYDROGENASE (UBIQUINONE) CYTOCHROME B SMALL SUBUNIT
Succinate dehydrogenase Cytochrome B small subunit
succinate dehydrogenase [ubiquinone] cytochrome B small subunit
Lipid storage droplets surface binding protein
testis-specifically expressed bromodomain containing protein-1
Adaptor Protein complex 1, sigma subunit
Sp1-like factor for Pairing Sensitive-silencing
Phenylalanyl-tRNA synthetase beta subunit
Phenylalanyl-tRNA synthetase, beta-subunit
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Nicotinamide mononucleotide adenylyltransferase
Nicotinamide mononucleotide adenylytransferase
nicotinamide mononucleotide adenyltransferase
nicotinamide mononucleotide adenylyl transferase 1
nicotinamide mononucleotide adenylyltransferase 1
glycosaminoglycan galactosyltransferase I
endoplasmic reticulum membrane protein complex 6
YTH N6-methyladenosine RNA binding protein
MAPK upstream kinase-binding inhibitory protein
NADH dehydrogenase (ubiquinone) 49 kDa subunit-like
NADH-ubiquinone oxidoreductase 49 kDa subunit
NADH:ubiquinone oxidoreductase 49 kDa subunit
Leucine-rich repeat-containing G protein-coupled receptor 3
Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
Isocitrate dehydrogenase (NAD+) 3 non-catalytic subunit gamma
alpha1,4-N-acetylgalactosaminyltransferase 2
α1,4-N-acetylgalactosaminyltransferase 2
Crustacean cardioactive peptide receptor
Phosphatidylinositol glycan anchor biosynthesis class P
Nuclear receptor binding SET domain protein
Ubiquinol-cytochrome c reductase 14 kDa subunit-like
Glutamine:fructose-6-phosphate aminotransferase 2
mitochondrial translation initiation factor 2
eukaryotic translation initiation factor 4E6
beta1,4-N-acetylgalactosaminyltransferase B
β1,4-N-acetylgalactosaminyltransferase B
BRD4 interacting chromatin remodeling complex associated protein
Pyruvate dehydrogenase E1 component subunit beta
choline transporter (CTL)-like protein 2
ALG13 UDP-N-acetylglucosaminyltransferase subunit
NADH dehydrogenase (ubiquinone) 20 kDa subunit-like
NADH: ubiquinone oxidoreductase-like, 20kDa subunit
General odorant-binding protein 99b precursor
Ubiquinol-cytochrome C reductase complex 11 kDa protein
Complex I intermediate- associate protein 30
Complex I intermediate-associated protein 30
Complex I intermediate-associated protein, 30 kDa
NADH:ubiquinone oxidoreductase complex assembly factor 1
Glucosamine-phosphate N-acetyltransferase
Electron transfer flavoprotein beta subunit
Electron transfer flavoprotein beta-subunit
Zinc/iron regulated transporter-related protein 99C
eukaryotic translation initiation factor 2B subunit alpha
tumor necrosis factor-alpha-converting enzyme
Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Zinc-finger protein interacting with CP190
Regulatory particle triple-A ATPase 6-related
eukaryotic translation initiation factor 4H2
F0/F1 ATP synthase Lipid-binding protein
Methylthioribose-1-phosphate isomerase 1
Cleavage stimulation factor 50 kD subunit
Small nuclear ribonucleoprotein U11/U12 subunit 59
Sodium-dependent multivitamin transporter
ATP binding cassette subfamily D member 1
ATP-binding cassette, subfamily D, member 1
Zinc/iron regulated transporter-related protein 102B
NADH dehydrogenase (ubiquinone) 49 kDa subunit
Phosphatidylinositol 5-phosphate 4-kinase
Mitochondrial inner membrane protein MPV17
Meiosis regulator and mRNA stability factor 1
Branched chain keto acid dehydrogenase E1 subunit beta
Enhancer on chromosome 2, complementation group b
UDP-glycosyltransferase family 317 member A1
Dihydroxyacetone phosphate acyltansferase
Dihydroxyacetone phosphate acyltransferase
Eukaryotic initiation factor 3 p66 subunit
eukaryotic translation initiation factor 3 subunit d1
UDP-glycosyltransferase family 304 member A1
UDP-glycosyltransferase family 302 member K1
UDP-glycosyltransferase family 303 member A1
UDP-glycosyltransferase family 35 member E1
UDP-glycosyltransferase family 35 member E2
UDP-glycosyltransferase family 35 member C1
UDP-glycosyltransferase family 302 member E1
UDP-glycosyltransferase family 302 member C1
UDP-glycosyltransferase family 37 member D1
UDP-glycosyltransferase family 37 member E1
UDP-glycosyltransferase family 37 member C2
c-Jun N-terminal kinase (JNK)-interacting protein
Metal response element-binding Transcription Factor-1
metal response element binding Transcription Factor 1
metal response element binding transcription factor
Glutamate-cysteine ligase catalytic subunit
catalytic subunit of glutamate- cysteine ligase
gamma-Glutamylcysteine synthetase catalytic subunit
γ-Glutamylcysteine synthetase catalytic subunit
Gram-negative bacteria binding protein 3
Gram-negative bacteria binding protein 2
Gram-negative bacteria binding protein 1
Leucine zipper like transcription regulator 1
eukaryotic translation initiation factor 4E7
Arylalkylamine N-Acetyltransferase Like 7
Arylalkylamine N-Acetyltransferase-like 7
NADH dehydrogenase (ubiquinone) B8 subunit
NADH-ubiquinone oxidoreductase B8 subunit
NADH:ubiquinone oxidoreductase B8 subunit
defective proboscis extension response 1
defective proboscis extension response 6
NADH:ubiquinone oxidoreductase subunit A3
CTP:phosphocholine cytidylyltransferase 1
eukaryotic translation initiation factor 2D
beta-N-acetylhexosaminidase beta subunit 2
beta-N-acetylhexosaminidase beta subunit 1
WASP family verprolin-homologous protein
UDP-glycosyltransferase family 305 member A1
Fatty acid synthase, methyl-branched specific
Protein phosphatase 2A regulatory B subunit
Microsomal glutathione S-transferase-like pseudogene
Chromatin accessibility complex 16kD protein
Chromatin accessibility complex 14kD protein
Adaptor Protein complex 2, sigma subunit
Male-specific insect derived growth factor
General odorant-binding protein 57a precursor
Peptidoglycan-recognition protein-SC2 precursor
Peptidoglycan-recognition protein-SC1a precursor
Peptidoglycan-recognition protein-SB1 precursor
small Cajal body-specific RNA : MeU5-C46
Chromo domain protein interacting with Z4
Stress-inducible humoral factor Turandot C
common type III glutamate receptor subunit
essential glutamate receptor subunit III
Glutamate-cysteine ligase modifier subunit
gamma-Glutamylcysteine synthetase regulatory subunit
γ-Glutamylcysteine synthetase regulatory subunit
differentially expressed in FDCP 8 homolog
NADH dehydrogenase (ubiquinone) 13 kDa B subunit
NADH-ubiquinone oxidoreductase 13 kDa-B subunit
NADH:ubiquinone oxidoreductase 13 kDa B subunit
Biogenesis of lysosome-related organelles complex 1, subunit 1
Endoplasmic reticulum stress-associated serine protease
drosophila Tp53 Regulated Inhibitor of Apoptosis 1
drosophila Tp53 Regulated Inhibitor of Apoptosis 2
Guanine nucleotide exchange factor in mesoderm
mitochondrial inner membrane subdomain organizer
mitochondrial inner membrane subdomain organizer 1
aaRS-interacting multifunctional protein 3
aminoacyl-tRNA synthetase-interacting multifunctional protein 3
transfer RNA:initiator Methionine-CAT 1-2
Major Facilitator Superfamily Transporter 1
Organic anion transporting polypeptide 58Da
(R)-4'-phospho-N-pantothenoylcysteine decarboxylase
Phosphopantothenoylcysteine decarboxylase
Ubiquinol-cytochrome c reductase 11 kDa protein
Ubiquinol-cytochrome c reductase 11 kDa subunit-like
ArfGAP with SH3 domain, ankyrin repeat and PH domain
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Phosphatidylinositol glycan anchor biosynthesis class X
testis-specifically expressed bromodomain containing protein-3
UDP-glycosyltransferase family 50 member B3
transfer RNA:Glutamic acid-CTC 5-1 pseudogene
transfer RNA:initiator Methionine-CAT 1-1
Polypeptide N-Acetylgalactosaminyltransferase 9
UDP-glycosyltransferase family 35 member D1
Prolyl 4-hydroxylase alpha salivary gland 1
SG specific ER protein prolyl-4-hydroxylase
Protein phosphatase 1c interacting protein 1
Seryl-tRNA synthetase-like insect mitochondrial protein
Efa6 pleckstrin and Sec7 domain containing
mitochondrial ribosome recycling factor 2
low density lipoprotein receptor-like 'a' repeats
70 kDa heat shock protein, cytosolic A 5
defective proboscis extension response 17
Organic anion transporting polypeptide 26F
Cytochrome c oxidase assembly protein COX11
Cytochrome c oxidase copper chaperone COX11
Transmembrane O-mannosyltransferase targeting cadherins 1
Interferon-related developmental regulator 1
CCR4-NOT transcription complex subunit 4
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Small nuclear ribonucleoprotein U11/U12 subunit 20
RAB3 GTPase activating protein catalytic subunit 1
RAB3 GTPase activating protein subunit 1
Polypeptide N-Acetylgalactosaminyltransferase 4
transfer RNA:Threonine-AGT 3-1 pseudogene
defective proboscis extension response 10
Short Calcium-binding Mitochondrial Carrier
LIM homeobox transcription factor 1 alpha
PAX transcription activation domain interacting protein
PAX transcription activation domain-interacting protein
hairpin RNA:Lsd1-interacting non-coding RNA 1
hairpin RNA:Lsd1-interacting non-coding RNA 3
cytidine monophosphate-sialic acid synthetase
NADH dehydrogenase (ubiquinone) MLRQ subunit
NADH-ubiquinone oxidoreductase MLRQ subunit
NADH:ubiquinone oxidoreductase MLRQ subunit
testis-specific gamma-tubulin ring protein 128
endoplasmic reticulum membrane protein complex 10
ACAT-related protein required for viability 1
transfer RNA:initiator Methionine-CAT 1-3
transfer RNA:Isoleucine-AAT 2-1 pseudogene
Histone gene-specific Epigenetic Repressor in late S phase
Suppression Of Retinal Degeneration Disease 1 upon overexpression 2
Nascent-associated complex beta-subunit-like, testis 6
Nascent-associated complex β-subunit-like, testis 6
defective proboscis extension response 8
Nascent-associated complex beta-subunit-like, testis 3
Nascent-associated complex β-subunit-like, testis 3
transfer RNA:Glutamic acid-CTC 6-1 pseudogene
Sperm-specific dynein intermediate chain 3
Calcitonin-like diuretic hormone receptor
Terminal ADP-ribose protein glycohydrolase 1
Terminal ADP-ribose protein glycohydrolase 2
delta-1-Pyrroline-5-carboxylate dehydrogenase 2
Eukaryotic translation initiation factor 4E homologous protein
defective proboscis extension response 11
Oligosaccharyltransferase complex subunit 1
defective proboscis extension response 7
Sperm-specific dynein intermediate chain 2
Sperm-specific dynein intermediate chain 4
defective proboscis extension response 4
defective proboscis extension response 3
VAMP-associated protein of 33kDa ortholog B
SET and MYND domain containing, arthropod-specific, member 8
Oligosaccharyltransferase complex subunit 4
Dolichyl-phosphate mannosyltransferase subunit 3
NADH dehydrogenase (ubiquinone) AGGG subunit
NADH:ubiquinone oxidoreductase AGGG subunit
Major Facilitator Superfamily Transporter 17
Haematopoietic stem/progenitor cell protein 300
L-threonylcarbamoyladenylate synthase type 1
hairpin RNA:Lsd1-interacting non-coding RNA 2
Glutamyl-tRNA amidotransferase, subunit C
glutamyl-tRNA amidotransferase subunit C
Acyl-CoA binding protein with ankyrin repeat
SRA stem-loop interacting RNA binding protein 1
Enhancer on chromosome 2, complementation group d
Actin-related protein 2/3 complex, subunit 3B
small Cajal body-specific RNA : MeU5-U42
small Cajal body-specific RNA : MeU2-C28
alternative testis transcripts open reading frame B
alternative testis transcripts open reading frame A
Sperm-specific dynein intermediate chain 1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
Cytochrome c oxidase subunit 7A1, mitochondrial
Biogenesis of lysosome-related organelles complex 1, subunit 3
Terminal ADP-ribose protein glycohydrolase 3
Small nuclear ribonucleoprotein U11/U12 subunit 25
SWIM domain containing Srs2 interacting protein 1
defective proboscis extension response 12
Exchange protein directly activated by cAMP
Exchange protein directly activated by cAMP ortholog
lymphocyte enhancer binding factor 1/T cell factor
Leucine-rich repeat-containing G protein-coupled receptor 4
NADH dehydrogenase (ubiquinone) MWFE subunit
NADH dehydrogenase (ubiquinone) AGGG subunit-like
effector for neural death and degeneration 2
TGF-beta-activated kinase 1/MAP3K7 binding protein 2
TGF-β–activated kinase 1/MAP3K7 binding protein 2
Phosphatidylinositol glycan anchor biosynthesis class Q
Drosophila Rhythmically expressed gene 3
Drosophila Hermansky-Pudlak Syndrome 5 subunit
pericentrin/AKAP450 centrosomal targeting
Chronologically inappropriate morphogenesis
chronologically -inappropriate morphogenesis
Protein-L-isoaspartate (D-aspartate) O-methyltransferase
protein D-aspartyl, L-isoaspartyl O-methyltransferase
Dalpha7 subunit of the acetylcholine receptor
Dalpha7 subunit of the nicotinic acetylcholine receptor
Dα7 subunit of the acetylcholine receptor
Dα7 subunit of the nicotinic acetylcholine receptor
nicotinic Acetylcholine Receptor alpha 18C
General receptor for phosphoinositides 1
general receptor for phosphoinositides-1
Pituitary adenylyl cyclase-activating polypeptide
Pituitary adenylyl cyclase-activating polypeptide-like
Nascent polypeptide associated complex protein alpha subunit
Retinoid and Fatty Acid Binding Glycoprotein
Retinoid- and Fatty Acid-binding Glycoprotein
Retinoid- and fatty acid-binding protein
Retinoid- and fatty-acid binding protein
Retinoid-fatty acid-binding glycoprotein
Supporter of Activation of Yellow Protein
5-hydroxytryptamine (serotonin) receptor 2A
Hyls1 centriolar and ciliogenesis associated
Jun N-terminal kinase dual-specificity phosphatase
GST-containing FLYWCH zinc-finger protein
Chromodomain-helicase-DNA-binding protein
Chromodomain-helicase-DNA-binding protein 1
chromo-ATPase/helicase-DNA-binding domain
chromo-ATPase/helicase-DNA-binding protein 1
soluble N-ethylmaleimide-sensitive factor attachment protein
Ubiquinol-cytochrome C reductase complex core protein 2
Ubiquinol-cytochrome c oxidoreductase Core protein 2
Ubiquinol-cytochrome c reductase Core protein 2
Doublecortin-domain-containing echinoderm-microtubule-associated protein
Doublecortin-domain-containing echinoderm-microtubule-associated protein ortholog
DNA polymerase alpha 148,000 alpha subunit
DNA polymerase alpha 182,000 alpha subunit
Dual-specificity tyrosine phosphorylation-regulated kinase 1A
Inositol polyphosphate-5-phosphatase type I
Neurogenic element binding transcription factor
decapentaplegic repression element binding protein
Protein kinase, cAMP-dependent, regulatory subunit type 1
type I regulatory subunit of cAMP-dependent protein kinase
DNA polymerase alpha 58,000 beta subunit
DNA polymerase alpha 60,000 beta subunit
Nop2/Sun-like domain containing protein 5
UDP-N-acetylglucosamine pyrophosphorylase
Dolichyl-phosphate mannosyltransferase subunit 2
Ubiquinol-cytochrome c oxidoreductase 11 kDa
Ubiquinol-cytochrome c reductase 11 kDa subunit
tRNA adenosine(37) threonylcarbamoyltransferase complex, dimerization subunit type 2
Drosophila melanogaster PSE-binding protein 49-kDa subunit
Proximal Sequence Element-Binding Protein 49
65 kDa regulatory subunit of protein phosphatase
regulatory subunit A of type 2A protein phosphatase
CCR4-NOT transcription complex subunit 10
Mitochondrial intermembrane space Import and Assembly 40
eukaryotic translation initiation factor 4G2
Death-associated inhibitor of apoptosis 1
Drosophila Inhibitor of Apoptosis Protein
Drosophila Inhibitor of Apoptosis Protein 1
Drosophila Inhibitor of Apoptosis Protein-1
Drosophila inhibitor-of-apoptosis protein 1
Drosophila thread/inhibitor of apoptosis protein-1
Coiled-coil-helix-coiled-coil-helix domain containing 2
Ubiquitously transcribed X chromosome tetratricopeptide repeat protein
Ubiquitously transcribed tetratricopetide repeat gene on the X chromosome
Glutamyl-tRNA amidotransferase, subunit A
Glutamyl-tRNA(Gln) amidotransferase, subunit A
glutamyl-tRNA amidotransferase subunit A
Toll pathway activation mediating protein
Na[+]-dependent inorganic phosphate cotransporter type III
Vesicle transport through interaction with t-SNAREs 1a
Drosophila damage-specific DNA-binding protein 1
Drosophila vesicular monoamine transporter
beta subunit of the SNF1/AMP-activated protein kinase
β subunit of the SNF1/AMP-activated protein kinase
defective proboscis extension response 21
Cleavage and polyadenylation specificity factor 73
cleavage and polyadenylation specificity factor, 73kD-subunit
beta-Amyloid precursor protein binding protein 1
β-Amyloid precursor protein binding protein 1
GTP-binding regulatory protein beta chain
Endoplasmic reticulum oxidoreductin-1-like
Drosophila sterol regulatory element binding protein
Sterol Regulatory Element Binding Protein
Sterol regulatory element-binding protein
sterol-responsive element-binding protein
transcription factor Sterol regulatory element binding protein
4'-phosphopantothenoylcysteine synthetase
LDLa domain containing chitin binding protein 1
LDLa domain containing chitin binding protein-1
Proteasome alpha3 subunit, Testis-specific
O-linked N-acetylglucosamine transferase
SUCCINYL COENZIME A SYNTHETASE FLAVOPROTEIN SUBUNIT
Succinate dehydrogenase, subunit A (flavoprotein)
Succinyl coenzyme A synthetase flavoprotein subunit
succinyl CoA synthetase flavoprotein subunit of complex II
small Cajal body-specific RNA : MeU2-G25
small Cajal body-specific RNA : MeU2-C41
small Cajal body-specific RNA : MeU4-A65
small Cajal body-specific RNA : MeU5-G38
Signal recognition particle 7SL RNA CR42652
Oxysterol-binding protein-related protein 8
eukaryotic initiation factor 4E binding protein
eukaryotic initiation factor 4E- binding protein
eukaryotic initiation factor 4E-binding protein
eukaryotic translation initiation factor 4E binding protein
eukaryotic translation initiation factor 4E-binding protein
insulin-stimulated eIF-4E binding protein
translation initiation factor 4E binding protein
Cyclic nucleotide-gated ion channel subunit A
Cyclic-nucleotide-gated ion channel protein
Small ribonucleoprotein particle protein D2
Small ribonucleoprotein particle protein SmD2
Small ribonucleoprotein particle protein SmE
Small ribonucleoprotein particle protein SmG
small ribonucleoprotein particle U1 subunit C
TATA box binding protein-related factor 2
TATA box-binding protein related factor 2
Mitotic spindle OrganiZing protein Associated with a Ring of g-Tubulin
mitochondrial carnitine palamitoyltransferase I
mitochondrial carnitine palmitoyltransferase I
defective proboscis extension response 2
5-hydroxytryptamine (serotonin) receptor 2B
ventral nervous system condensation defective
Small ribonucleoprotein particle protein SmD1
Ca[2+] channel Muscle-specific alpha2/delta subunit
Ran-Binding Protein in the Microtubule Organizing Center
Nascent-associated complex beta-subunit-like, testis 5
Nascent-associated complex β-subunit-like, testis 5
Rab3-interacting molecule (RIM)-binding protein
Vacuolar H[+] ATPase AC45 accessory subunit
Vacuolar H[+] ATPase accessory protein AC45
Transient receptor potential cation channel, mucolipin
Transient receptor potential cation channel, mucolipin ortholog
Drosophila sterile alpha and Armadillo motif
sterile alpha, ARM, and TIR domain protein
SET and MYND domain containing, arthropod-specific, member 3
Small ribonucleoprotein particle protein B
Small ribonucleoprotein particle protein SmB
Tetraspan membrane protein in hair cell stereocilia
Tetraspan membrane protein in hair cell stereocilia ortholog
Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase
Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2
Peptidyl-α-hydroxyglycine-α-amidating lyase
Peptidyl-α-hydroxyglycine-α-amidating lyase 2
eukaryotic translation initiation factor 4H1
ductin, vacuolar H(+)-ATPase subunit C proteolipid
Ecotropic viral integration site 5 ortholog
Ubiquinol-cytochrome c reductase 6.4 kDa subunit-like
Glial cell line-derived neurotrophic family receptor-like
Rabaptin-5-associated exchange factor for Rab5
Rabaptin-5-associated exchange factor for Rab5 ortholog
Mitochondrial NADH-ubiquinone oxidoreductase chain 4
RNA polymerase II second largest subunit
Sarco/endoplasmic reticulum Ca(2+)-ATPase
endoplasmic reticulum-specific calcium-transporting ATPase
sarco endoplasmic reticulum calcium-ATPase
sarco/endoplasmic reticulum-type Ca-2+-ATPase
sarcoplasmic endoplasmic reticulum calcium ATPase type 2
Heterochromatin Protein 1L chromoshadow domain
5-hydroxytryptamine (serotonin) receptor 1B
mitochondrial translation elongation factor G 1
Galactose-1-phosphate uridylyltransferase
small Cajal body-specific RNA : MeU1b-A234
Molybdenum cofactor synthesis 1 ortholog
Cyclic nucleotide-gated ion channel-like
ovarian hu-li tai shao-ring canal protein
Ten-Eleven Translocation (TET) family protein
small Cajal body-specific RNA : PsiU2-38.40.42
small Cajal body-specific RNA : ΨU2-38.40.42
small Cajal body-specific RNA : PsiU2-35.45
small Cajal body-specific RNA : ΨU2-35.45
small Cajal body-specific RNA : PsiU2-55
small Cajal body-specific RNA : PsiU6-40
small Cajal body-specific RNA : PsiU5-44
eukaryotic translation initiation factor 2 subunit gamma
gamma subunit of the translation initiation factor eIF2
3-Hydroxy-3-Methylglutaryl CoA Reductase
3-hydroxy-3-methylglutaryl coenzyme A reductase
mitochondrial ribosomal protein large subunit 45
Enhancer on chromosome 2-complementation group 2g
Translocase of the inner mitochondrial membrane 17b
Chromatin assembly factor 1, p55 subunit
cg43782 gene product from transcript cg43782-rh
AMP-activated protein kinase gamma subunit
SNF4/AMP-activated protein kinase gamma subunit
Ca[2+]-channel protein alpha[[1]] subunit T
alpha subunit of Drosophila casein kinase II
α subunit of Drosophila casein kinase II
Cul3-Hedghog-induced MATH and BTB domain-containing protein
Hh-induced MATH and BTB domain containing protein
Ca2+/calmodulin-dependent protein kinase II
Ca[2+]-calmodulin-dependent protein kinase II
Ca[2+]/Calmodulin-dependent protein kinase II
Calcium/calmodulin-dependent protein kinase II
calcium/ calmodulin-dependent protein kinase II
calcium/calmodulin-dependent protein kinase type II
EGF-domain specific O-GlcNAc transferase
Rho guanine nucleotide exchange factor 3
Vesicle transport through interaction with t-SNAREs 1b
Thioester-containing protein 5 pseudogene
Adaptor Protein complex 2, alpha subunit
Pcf11 cleavage and polyadenylation factor subunit
Protein 1 of cleavage and polyadenylation factor 1
Chondrocyte-derived ezrin-like domain containing protein
Chondrocyte-derived ezrin-like domain containing protein ortholog
eukaryotic translation initiation factor 4E-3
eukaryotic translation initiation factor 4E3
Phosphatidylinositol glycan anchor biosynthesis class V
Phosphatidylinositol glycan anchor biosynthesis, class V
Phosphatidylinositol glycan anchor biosynthesis, class V ortholog
Small nuclear ribonucleoprotein U11/U12 subunit 65
Phosphatidylinositol glycan anchor biosynthesis class S
Phosphatidylinositol glycan anchor biosynthesis, class S
Phosphatidylinositol glycan anchor biosynthesis, class S ortholog
Transient receptor potential cation channel, subfamily M
Transient receptor potential cation channel, subfamily M ortholog
tubulin-specific chaperone E-like protein
SMRT-related ecdysone receptor interacting factor
SMRT-related ecdysone receptor-interacting factor
silencing mediator of retinoid and thyroid hormone receptors-related ecdysone receptor-interacting factor
Ras-related protein interacting with calmodulin
Ras-related which interacted with Calmodulin
Proteasome alpha4 subunit, Testis-specific 1
Proteasome α4 subunit, Testis-specific 1
PDZ domain-containing guanine nucleotide exchange factor
Cyclic-AMP response element binding protein B
Cyclic-AMP response element binding protein B at 17A
Cyclic-AMP response element binding protein B at 17B
Z band alternatively spliced PDZ-motif containing protein 52
Z band alternatively spliced PDZ-motif protein
Z band alternatively spliced PDZ-motif protein 52
Protein associated with topo II related - 1
Formin homology 2 domain containing ortholog
hydroxyurea- and (or) caffeine-sensitive 95E
Cyclic nucleotide-gated ion channel subunit B
Cyclic-nucleotide-gated ion channel protein beta-subunit
Cyclic-nucleotide-gated ion channel protein β-subunit
nicotinic Acetylcholine Receptor alpha 4
nicotinic Acetylcholine Receptor alpha 80B
Microsomal triacylglycerol transfer protein
Microsomal triglyceride transfer protein
Tubulin Polymerization Promoting Protein
Phosphatidylinositol glycan anchor biosynthesis class Z
DNA polymerase interacting tpr containing protein of 47kD
NADH dehydrogenase (ubiquinone) 30 kDa subunit
NADH dehydrogenase (ubiquinone) Fe-S protein 3
NADH-UBIQUINONE OXIDOREDUCTASE 30 KDA SUBUNIT
NADH:ubiquinone oxidoreductase 30 kDa subunit
nuclear-encoded subunit NDUFS3 of complex I
kinetochore Mis12-Ndc80 network component 2
70 kDa heat shock protein, cytosolic B 2
BIR repeat containing ubiquitin-conjugating enzyme
Extended synaptotagmin-like protein 2 ortholog
Cytoplasmic Protein tyrosine phosphatase 62A
ribosomal RNA primary transcript:CR45845
ribosomal RNA primary transcript:CR45846
ribosomal RNA primary transcript:CR45847
ribosomal RNA primary transcript pseudogene:CR45856
ribosomal RNA primary transcript:CR45856
downstream non-coding target of Rpd3 and Loco
downstream noncoding target of Rpd3 and Loco
Heterogeneous nuclear ribonucleoprotein S5
heterogeneous nuclear ribonucleoprotein M
Heterogeneous nuclear ribonucleoprotein K
Heterogeneous nuclear ribonucleoprotein at 57A
GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase
GDP-keto-6-deoxymannose 3,5-epimerase/4-reductase
Fatty acid (long chain) transport protein
protein phosphatase from PCR fragment D27
Translocase of inner mitochondrial membrane 23
Phenylalanyl-tRNA synthetase, mitochondrial
mitochondrial phenylalanyl-tRNA synthetase
Structure specific recognition protein 2
Sperm-specific dynein intermediate chain A
Sperm-specific dynein intermediate chain B
Sperm-specific dynein intermediate chain C
insulin/insulin-like growth factor receptor
Neuralized E3 ubiquitin protein ligase 4
Peptidyl gycine alpha hydroxylating monooxygenase
Peptidyl gycine α hydroxylating monooxygenase
Peptidylglycine-alpha-hydroxylating monooxygenase
Peptidylglycine-α-hydroxylating monooxygenase
peptidylglycine alpha-hydroxylating monooxygenase
peptidylglycine α-hydroxylating monooxygenase
Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 1
Peptidyl-α-hydroxyglycine-α-amidating lyase 1
Dihydrolipoyllysine-residue acetyltransferase
tRNA adenosine(37) threonylcarbamoyltransferase complex, transferase subunit
eukaryotic translation elongation factor 1 alpha 1
Leucine zipper and EF-hand containing transmembrane protein 1
Actin-related protein 2/3 complex, subunit 4
Insulin-like Growth Factor 2 mRNA Binding Protein 1
eukaryotic translation elongation factor 5
Sarcoma-associated RNA-binding fly homolog
ADAM metallopeptidase with thrombospondin type 1 motif A
Drosophila lysine ketoglutarate reductase
Drosophila lysine ketoglutarate reductase (dLKR)/saccharopine dehydrogenase (SDH)
Lysine Ketoglutarate Reductase/Saccharopine Dehydrogenase
Phosphatidylcholine-specific phospholipase-D
small Cajal body-specific RNA : MeU1-A24
small Cajal body-specific RNA : MeU4:25F-C137
Electron transfer flavoprotein-ubiquinone oxidoreductase
electron transfer flavoprotein:ubiquinone oxidoreductase
TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE TER94
Transitional endoplasmic reticulum ATPase
Glutamine: Fructose-6-Phosphate Aminotransferase 1
Glutamine:fructose-6-phosphate aminotransferase 1
Calmodulin-binding transcription activator
CDP-diacylglycerol-serine O-phosphatidyltransferase
Cleavage and polyadenylation specific factor 5
msa micropeptide small open reading frame
alpha-ketoglutarate dehydrogenase E3 subunit
α-ketoglutarate dehydrogenase E3 subunit
eukaryotic translation Initiation Factor 2
eukaryotic translation Initiation Factor 2alpha
eukaryotic translation Initiation Factor 2alpha kinase
eukaryotic translation Initiation Factor 2α
eukaryotic translation Initiation Factor 2α kinase
eukaryotic translation initiation factor 2 subunit alpha
Glutamyl-tRNA amidotransferase, subunit B
glutamyl-tRNA amidotransferase subunit B
multiple ankyrin repeats single KH domain
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.
Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.
single-stranded DNA endodeoxyribonuclease activity
single-stranded DNA endonuclease activity
Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.
Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.
Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme.
Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.
Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.
L-ornithine transmembrane transporter activity
Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
regulation of cyclin-dependent protein serine/threonine kinase activity
Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.
sulphur amino acid transmembrane transporter activity
sulfur amino acid transmembrane transporter activity
The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
down regulation of transcription from RNA polymerase II promoter
down-regulation of transcription from RNA polymerase II promoter
downregulation of transcription from RNA polymerase II promoter
inhibition of transcription from RNA polymerase II promoter
negative regulation of transcription from Pol II promoter
negative regulation of transcription from RNA polymerase II promoter
negative regulation of transcription by RNA polymerase II
A motor activity that generates movement along a microfilament, driven by ATP hydrolysis.
Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
mitogen-activated protein kinase cascade
Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
Binding to a DNA sequence encoding a ribosomal RNA.
Catalysis of the reaction: pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.
Binding to a DNA secondary structure element such as a four-way junction, a bubble, a loop, Y-form DNA, or a double-strand/single-strand junction.
Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.
N-acetylglucosaminylphosphatidylinositol deacetylase activity
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
A chromosome found in the mitochondrion of a eukaryotic cell.
Binding to a peroxisomal targeting sequence, a short stretch of amino acids found in a protein that acts as a signal to localize the protein to the peroxisome.
peroxisome signal sequence receptor activity
Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + H+.
phosphatidylinositol-3-phosphate 5-kinase activity
1-phosphatidylinositol-3-phosphate 5-kinase activity
Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.
adenine nucleotide transmembrane transporter activity
Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues.
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
response to reactive oxygen intermediate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.
Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + ATP + H+ = diphosphate + NAD+.
ATP:nicotinamide-nucleotide adenylyltransferase activity
nicotinamide-nucleotide adenylyltransferase activity
A ribosome contained within a subcellular membrane-bounded organelle.
Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.
Splicing of RNA via a series of two transesterification reactions.
RNA splicing, via transesterification reactions
Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.
second spliceosomal transesterification activity
Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.
Binding to a DNA segment shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end.
A histone chaperone that carries a H3-H4 histone complex.
H3-H4 histone complex chaperone activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-sulfino-L-alanine (cysteinesulfinate) (out) + H+(in) + L-glutamate(in) = 3-sulfino-L-alanine(in) + H+(out) + L-glutamate(out).
3-sulfino-L-alanine: proton, glutamate antiporter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-aspartate(in) + L-glutamate(out) = H+(in) + L-aspartate(out) + L-glutamate(in).
aspartate:glutamate, proton antiporter activity
Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
mismatch base pair DNA N-glycosylase activity
Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
oxidized base lesion DNA N-glycosylase activity
Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.
oxidized pyrimidine base lesion DNA N-glycosylase activity
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.
adenyl-nucleotide exchange factor activity
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + H+.
inositol-1,4,5-trisphosphate 6-kinase activity
Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
inositol hexakisphosphate kinase activity
Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
translation repressor activity, mRNA regulatory element binding
mRNA regulatory element binding translation repressor activity
The developmental process in which the size or shape of a cell is generated and organized.
The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
regulation of mitochondrial RNA catabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
negative regulation of mitochondrial RNA catabolic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
positive regulation of mitochondrial RNA catabolic process
The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.
Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.
Any process involved in forming the mature 5' end of an RNA molecule.
Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
transcription regulatory region sequence-specific DNA binding
transcription cis-regulatory region binding
Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
RNA polymerase II transcription regulatory region sequence-specific DNA binding
Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.
RNA polymerase II cis-regulatory region sequence-specific DNA binding
Binding to a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.
RNA polymerase II core promoter sequence-specific DNA binding
A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding
sequence-specific DNA binding RNA polymerase II transcription factor activity
DNA-binding transcription factor activity, RNA polymerase II-specific
Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site, located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. Cis-regulatory sites are often referred to as a sequence motifs, enhancers, or silencers.
cis-regulatory region sequence-specific DNA binding
Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes.
RNA polymerase III cis-regulatory region sequence-specific DNA binding
Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
Binding to an RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.
A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III.
RNA polymerase III general initiation factor activity
RNA polymerase III general transcription initiation factor activity
Binding to a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.
mitochondrial single-subunit type RNA polymerase binding
Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.
RNA polymerase III type 1 promoter sequence-specific DNA binding
Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.
RNA polymerase III type 2 promoter sequence-specific DNA binding
Binding to a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
RNA polymerase III type 3 promoter sequence-specific DNA binding
Binding to a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
RNA polymerase III transcription regulatory region sequence-specific DNA binding
Binding to a DNA region that controls the transcription of the mitochondrial DNA.
mitochondrial promoter sequence-specific DNA binding
Binding to an RNA polymerase III transcription factor, a protein required to initiate or regulate transcription by RNA polymerase III.
RNA polymerase III general transcription initiation factor binding
Binding to a RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.
Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
core promoter sequence-specific DNA binding
Binding to a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.
single-subunit type RNA polymerase binding
Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
transcription regulatory region nucleic acid binding
Binding to a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
Binding to a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
RNA polymerase II basal transcription factor binding
RNA polymerase II general transcription initiation factor binding
Binding to a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
TFIIA-class transcription factor binding
TFIIA-class transcription factor complex binding
Binding to a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIIB-class transcription factor binding
Binding to a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIID-class transcription factor binding
TFIID-class transcription factor complex binding
Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIIF-class transcription factor binding
TFIIF-class transcription factor complex binding
Binding to a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIIH-class transcription factor binding
TFIIH-class transcription factor complex binding
Binding to a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.
transcription termination site sequence-specific DNA binding
Binding to a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.
TFIIIC-class transcription factor binding
TFIIIC-class transcription factor complex binding
Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.
RNA polymerase I transcription regulatory region sequence-specific DNA binding
Binding to a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE.
RNA polymerase I CORE element sequence-specific DNA binding
RNA polymerase I core promoter sequence-specific DNA binding
A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs.
RNA polymerase I transcription general initiation factor activity
general RNA polymerase I transcription factor activity
RNA polymerase I general transcription initiation factor activity
The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides.
RNA polymerase I transcriptional preinitiation complex assembly
RNA polymerase I preinitiation complex assembly
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
DNA-binding transcription activator activity
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
DNA-binding transcription repressor activity
Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
Binding to a transcription corepressor, a protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.
Binding to a transcription coactivator, a protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription repressor activity, RNA polymerase II-specific
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other.
guanine nucleotide transmembrane transporter activity
The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.
N-acetylglucosamine 6-O-sulphotransferase activity
N-acetylglucosamine 6-O-sulfotransferase activity
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
Binding to an amyloid-beta peptide/protein.
The series of events required for a sour taste stimulus to be received and converted to a molecular signal.
perception of sour taste, detection of chemical stimulus
perception of sour taste, sensory transduction of chemical stimulus
sensory detection of chemical stimulus during perception of sour taste
sensory transduction of chemical stimulus during perception of sour taste
detection of chemical stimulus involved in sensory perception of sour taste
The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.
perception of sweet taste, detection of chemical stimulus
perception of sweet taste, sensory transduction of chemical stimulus
sensory detection of chemical stimulus during perception of sweet taste
sensory transduction of chemical stimulus during perception of sweet taste
detection of chemical stimulus involved in sensory perception of sweet taste
Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.
dopamine neurotransmitter receptor activity, coupled via Gs
Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity.
dopamine neurotransmitter receptor activity, coupled via Gi/Go
Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
G protein coupled adenosine receptor activity
G-protein coupled adenosine receptor activity
adenosine receptor activity, G protein coupled
adenosine receptor activity, G-protein coupled
G protein-coupled adenosine receptor activity
Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
adenylyl cyclase inhibiting metabotropic glutamate receptor activity
adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.
group II metabotropic glutamate receptor activity
Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
Binding to a G protein-coupled receptor.
Binds to and increases the activity of an ATP hydrolysis activity.
The chemical reactions and pathways involving a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
translation initiation ternary complex assembly
formation of translation initiation ternary complex
Catalysis of the phosphorylation of a simple or complex lipid.
Catalysis of the reaction: an N-acylsphing-4-enine + ATP = ADP + an N-acylsphing-4-enine 1-phosphate + H+.
Catalysis of the reaction: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H+ + S-adenosyl-L-homocysteine. This activity is the methylation of adenines in mRNA with the consensus sequence RRACH, where R is a purine, and H is C, A, or U.
mRNA (N6-adenosine)-methyltransferase activity
Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.
beta-alanine transmembrane transporter activity
The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Binding to a phosphorylated tyrosine residue within a protein.
Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
Combining with (1->3)-beta-D-glucans to initiate an innate immune response.
(1->3)-beta-D-glucan immune receptor activity
Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
lipopolysaccharide immune receptor activity
Catalysis of the reaction: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H+ + UDP.
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
regulation of protein amino acid phosphorylation
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
down regulation of protein amino acid phosphorylation
down-regulation of protein amino acid phosphorylation
downregulation of protein amino acid phosphorylation
negative regulation of protein amino acid phosphorylation
negative regulation of protein phosphorylation
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
positive regulation of protein amino acid phosphorylation
up regulation of protein amino acid phosphorylation
up-regulation of protein amino acid phosphorylation
upregulation of protein amino acid phosphorylation
positive regulation of protein phosphorylation
Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.
regulation of cytokine and chemokine mediated signaling pathway
regulation of cytokine mediated signaling pathway
regulation of cytokine mediated signalling pathway
regulation of cytokine-mediated signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.
down regulation of cytokine mediated signaling pathway
down-regulation of cytokine mediated signaling pathway
downregulation of cytokine mediated signaling pathway
negative regulation of cytokine and chemokine mediated signaling pathway
negative regulation of cytokine mediated signaling pathway
negative regulation of cytokine mediated signalling pathway
negative regulation of cytokine-mediated signaling pathway
Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
positive regulation of cytokine and chemokine mediated signaling pathway
positive regulation of cytokine mediated signaling pathway
positive regulation of cytokine mediated signalling pathway
up regulation of cytokine mediated signaling pathway
up-regulation of cytokine mediated signaling pathway
upregulation of cytokine mediated signaling pathway
positive regulation of cytokine-mediated signaling pathway
The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.
The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
adenosine receptor signaling pathway, G-protein coupled
G protein-coupled adenosine receptor signaling pathway
Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Binding to one of the p53 family of proteins.
Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.
Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.
Binding to a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton.
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
The hydrolysis of an incorrectly aminoacylated tRNA.
Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
response to bacteria associated molecule
response to bacterial associated molecule
response to bacterium associated molecule
response to molecule of bacterial origin
Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
regulation of response to biotic stimulus
Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
down regulation of response to biotic stimulus
down-regulation of response to biotic stimulus
downregulation of response to biotic stimulus
negative regulation of response to biotic stimulus
Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
up regulation of response to biotic stimulus
up-regulation of response to biotic stimulus
upregulation of response to biotic stimulus
positive regulation of response to biotic stimulus
The process whereby a uridine in a transfer RNA is converted to dihydrouridine.
Catalysis of the reaction: an N-acyl-sphingoid base + CDP-ethanolamine = an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H+.
ceramide phosphoethanolamine synthase activity
Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate.
A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
The process in which an amino acid is transported across a membrane.
A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
Unwinding of a DNA helix, driven by ATP hydrolysis.
Binding to a DNA structure formed by the minor groove of adenine-thymine-rich DNA regions. Examples of proteins having this function are AT-rich interaction domain (ARID)-containing proteins.
minor groove of adenine-thymine-rich DNA binding
Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis.
Binding to double-stranded telomere-associated DNA.
Binding to a P-element, a class of Drosophila transposon responsible for hybrid dysgenesis.
Binding to satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA.
A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
DNA binding transcription factor activity
gene-specific transcription factor activity
sequence-specific DNA binding transcription factor activity
DNA-binding transcription factor activity
A molecular function that stimulates the elongation properties of the RNA polymerase during the elongation phase of transcription. A subclass of transcription elongation factors enable the transition from transcription initiation to elongation, while another class rescue stalled RNA polymerases.
transcription elongation factor activity
A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.
A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.
A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.
Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) using an internal RNA template that encodes the telomeric repeat sequence.
telomerase RNA reverse transcriptase activity
Binding to an RNA molecule or a portion thereof.
Unwinding of an RNA helix, driven by ATP hydrolysis.
Catalysis of the reaction: adenosine + H2O = inosine + NH4+, in a double-stranded RNA molecule.
double-stranded RNA adenosine deaminase activity
Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
Binding to a 3' untranslated region of an mRNA molecule.
The action of a molecule that contributes to the structural integrity of the ribosome.
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
Functions in chain elongation during polypeptide synthesis at the ribosome.
Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
peptidyl-prolyl cis-trans isomerase activity
Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).
A motor activity that generates movement along a microtubule, driven by ATP hydrolysis.
ATP-dependent microtubule motor activity
Binding to monomeric or multimeric forms of actin, including actin filaments.
Binding to monomeric actin, also known as G-actin.
Binding to an actin monomer to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.
mucopeptide N-acetylmuramoylhydrolase activity
Catalysis of the reaction: L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4+. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links.
protein-glutamine gamma-glutamyltransferase activity
Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. Antigen binding by an MHC protein complex allows the antigen to be displayed to a T cell or NK cell.
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.
UDP-glucose-glucose-phosphate glucosyltransferase activity
UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity
trehalose 6-phosphate synthetase activity
trehalosephosphate-UDP glucosyl transferase activity
trehalosephosphate-UDP glucosyltransferase activity
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H+ + UDP.
alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
Catalysis of the reaction: beta-alanyl-dopamine + H2O = dopamine + beta-alanine.
N-beta-alanyl-dopamine hydrolase activity
Catalysis of the synthesis of beta-alanyl amine conjugate from a precursor biogenic amine, such as dopamine or histamine.
N-beta-alanyl dopamine synthetase activity
Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.
beta-carotene 15,15'-dioxygenase activity
Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactoside = N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H+.
beta-galactosamide alpha-2,6-sialyltransferase activity
beta-galactoside alpha-(2,6)-sialyltransferase
beta-galactoside alpha-2,6-sialyltransferase activity
Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH4+.
Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.
(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)
gamma-L-glutamylcyclotransferase activity
gamma-glutamyl-amino acid cyclotransferase activity
L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + 2 H+.
L-glutamate gamma-semialdehyde dehydrogenase activity
Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.
2-acylglycerol O-acyltransferase activity
Catalysis of the reaction: a (3S)-3-hydroxyacyl-CoA + NAD+ = a 3-oxoacyl-CoA + NADH + H+.
(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
Catalysis of the reaction: glycine + H+ + succinyl-CoA = 5-aminolevulinate + CO2 + CoA.
Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.
Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H+.
Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H+ + triphosphate.
6-pyruvoyltetrahydropterin synthase activity
Catalysis of the reactions: H2O + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] = ADP-D-ribose + L-arginyl-[protein], and H2O + N(omega)-(ADP-D-ribosyl)-L-arginine = ADP-D-ribose + L-arginine.
ADP-ribosylarginine-[protein] hydrolase activity
Catalysis of the reaction: AMP + H2O = IMP + NH4+.
Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.
C-terminal protein carboxyl methyltransferase activity
protein C-terminal carboxyl O-methyltransferase activity
Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H+.
CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity
Catalysis of the reaction: ATP + UTP + glutamine + H20= ADP + phosphate + CTP + glutamate.
Catalysis of the reaction: a D-alpha-amino acid + H2O + O2 = a 2-oxocarboxylate + H2O2 + NH4+.
Catalysis of the reaction: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H+ + S-adenosyl-L-homocysteine.
DNA (cytosine-5-)-methyltransferase activity
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light.
deoxyribodipyrimidine photolyase activity
deoxyribodipyrimidine photo-lyase activity
Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).
apurinic/apyrimidinic endodeoxyribonuclease activity
apyrimidinic deoxyendoribonuclease activity
deoxyribonuclease (apurinic or apyrimidinic) activity
DNA-(apurinic or apyrimidinic site) endonuclease activity
Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.
DNA-6-O-methylguanine:[protein]-L-cysteine S-methyltransferase activity
methylated-DNA-[protein]-cysteine S-methyltransferase activity
Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.
Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).
Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA.
Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
DNA topoisomerase type I (single strand cut, ATP-independent) activity
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
Catalysis of the reaction: ATP + FMN = diphosphate + FAD.
Catalysis of the reaction: ATP + XMP + NH4+ = AMP + diphosphate + GMP + 2H+.
Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H+.
GMP synthase (glutamine-hydrolyzing) activity
Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor.
Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).
Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
Catalysis of the reaction: GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H+.
Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide.
Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.
Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. Acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.
L-iditol 2-dehydrogenase (NAD+) activity
Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate. Can also hydrolyze alpha-L-iduronosidic linkages in heparan sulfate.
Catalysis of the reaction: L-serine = pyruvate + NH4+.
L-serine hydro-lyase (deaminating) activity
Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H+.
N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity
Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
NAD+ poly-ADP-ribosyltransferase activity
Catalysis of the reaction: ATP + NAD+ = ADP + H+ + NADP+.
Catalysis of the reaction: deamido-NAD+ + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD+ + H+.
NAD synthase (glutamine-hydrolyzing) activity
NAD+ synthase (glutamine-hydrolyzing) activity
Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate.
Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time.
Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + H2O2.
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.
UDP-N-acetylglucosamine 4-epimerase activity
Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine.
UDP-N-acetylglucosamine pyrophosphorylase activity
UDP-N-acetylglucosamine diphosphorylase activity
Catalysis of the reaction: UDP-glucose = UDP-galactose.
Catalysis of the reaction: H2O + 2 NAD+ + UDP-alpha-D-glucose = 3 H+ + 2 NADH + UDP-alpha-D-glucuronate.
Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.
UDP-glucose:glycoprotein glucosyltransferase activity
Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
UTP:glucose-1-phosphate uridylyltransferase activity
Catalysis of the reaction: acetylcholine + H2O = choline + acetate.
Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.
Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
Catalysis of the reaction: a 2,3-saturated acyl-CoA + H+ oxidized [electron-transfer flavoprotein] = a (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].
Catalysis of the reaction: a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2.
Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.
Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
adenine phosphoribosyltransferase activity
Catalysis of the reaction: adenosine + H2O = inosine + NH4+.
Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.
Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
Catalysis of the reaction: ATP + AMP = 2 ADP.
Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H+ + phosphate.
Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
L-alanine:2-oxoglutarate aminotransferase activity
L-alanine:2-oxoglutarate transaminase activity
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
Catalysis of the reaction: an aldehyde + H2O + NAD+ = a carboxylate + 2 H+ + NADH.
Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
aldehyde dehydrogenase [NAD(P)+] activity
Catalysis of the reaction: an aldehyde + O2 + H2O = a carboxylate + H2O2 + H+.
Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.
Catalysis of the reaction: a phosphate monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH4+.
Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O.
Catalysis of the reaction: an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H+.
Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
Catalysis of the reaction: N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4+.
Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.
Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.
Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.
Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.
aromatic-L-amino-acid decarboxylase activity
Catalysis of the reaction: a 2-arylethylamine + acetyl-CoA = an N-acetyl-2-arylethylamine + CoA + H+.
aralkylamine N-acetyltransferase activity
Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.
asparagine synthase (glutamine-hydrolyzing) activity
Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH4+.
Catalysis of the reaction: L-aspartate = beta-alanine + CO2.
Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
L-aspartate:2-oxoglutarate aminotransferase activity
L-aspartate:2-oxoglutarate transaminase activity
Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H+ + phosphate.
Catalysis of the reaction: bilirubin IXalpha + NAD(P)+ = biliverdin IXalpha + NAD(P)H + H+.
Catalysis of the reaction: ATP + biotin + L-lysyl-[protein] = AMP + diphosphate + H+ + N(6)-biotinyl-L-lysyl-[protein].
biotin--[biotin carboxyl-carrier protein] ligase activity
Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
Catalysis of the reaction: a branched-chain amino acid (L-leucine, L-isoleucine and L-valine) + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
branched-chain amino acid aminotransferase activity
branched-chain-amino-acid transaminase activity
branched-chain-amino-acid:2-oxoglutarate transaminase activity
Catalysis of the reaction: hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H+.
carbamoyl phosphate synthase (glutamine-hydrolyzing) activity
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Catalysis of the reaction: hydrogencarbonate + H+ = CO2 + H2O.
Catalysis of the reaction: a secondary alcohol + NADP+ = a ketone + H+ + NADPH.
Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA.
Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.
carnitine O-palmitoyltransferase activity
Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O.
Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O. This reaction catalyzes exclusively the oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones.
Catalysis of the reaction: chitin + H2O = chitosan + acetate.
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).
Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.
Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H+.
Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.
Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline.
CTP:choline-phosphate cytidylyltransferase activity
choline-phosphate cytidylyltransferase activity
Catalysis of the reaction: coproporphyrinogen III + 2 H+ + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX.
Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.
cyclic-nucleotide phosphodiesterase activity
Catalysis of the reaction: a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate.
3',5' cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
Catalysis of the reaction: 3',5'-cyclic AMP + H2O = AMP + H+.
3',5' cAMP-specific phosphodiesterase activity
3',5'-cAMP-specific phosphodiesterase activity
3',5'-cyclic-AMP-specific phosphodiesterase activity
adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity
cAMP-specific phosphodiesterase activity
cyclic AMP-specific phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
Catalysis of the reactions: 3',5'-cyclic AMP + H2O = AMP + H+ and 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.
calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity
Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.
Catalysis of the reaction: 2 Fe(III)-[cytochrome b5] + NAD(P)H = 2 Fe(II)-[cytochrome b5] + NAD(P)+ + H+.
cytochrome-b5 reductase activity, acting on NAD(P)H
Catalysis of the reaction: 4 Fe(II)-[cytochrome c] + O2 + 8 H+(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H+(out).
Catalysis of the reaction: dCMP + H2O = dUMP + NH4+.
Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.
Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H+.
Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H+.
Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.
Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.
diacylglycerol cholinephosphotransferase activity
Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+.
ATP-dependent diacylglycerol kinase activity
Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.
diacylglycerol O-acyltransferase activity
Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.
Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA.
dihydrolipoamide S-succinyltransferase activity
dihydrolipoyllysine-residue succinyltransferase activity
Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H+.
Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH4+.
Catalysis of the reaction: NAD(P)+ + 5,6,7,8-tetrahydropteridine = NAD(P)H + H+ + 6,7-dihydropteridine.
Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.
Catalysis of the reactions: a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA or a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.
delta3-cis-delta2-trans-enoyl-CoA isomerase
delta3-delta2 enoyl-CoA isomerase activity
delta(3)-delta(2)-enoyl-CoA isomerase activity
Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.
Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.
Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.
dolichyl-phosphate-mannose-protein O-mannosyltransferase activity
dolichyl-phosphate-mannose-protein mannosyltransferase activity
Catalysis of the reaction: dUTP + H2O = dUMP + H+ + diphosphate.
Catalysis of the reaction: a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H+ + oxidized [electron-transfer flavoprotein].
electron-transferring-flavoprotein dehydrogenase activity
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.
Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain.
Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain.
Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.
calcium-dependent cysteine-type endopeptidase activity
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
Catalysis of the reaction: a 3-hydroxy-fatty acyl-CoA = a enoyl-CoA + H2O. This reaction usually occurs in the reverse direction, leading to the reduction of the double bound of enoyl-CoA in position 2 or 3. Specific reactions catalyzed include: a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O and a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O.
short-chain enoyl-CoA hydratase activity
Catalysis of the reaction: an epoxide + H2O = an ethanediol.
Catalysis of the reaction: estradiol-17-beta + NAD(P)+ = estrone + NAD(P)H + H+. The activity can use NAD+ or NADP+ as the acceptor.
estradiol 17-beta-dehydrogenase [NAD(P)+] activity
Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H+ + phosphoethanolamine.
Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.
CTP:ethanolamine-phosphate cytidylyltransferase activity
phosphoethanolamine cytidylyltransferase activity
ethanolamine-phosphate cytidylyltransferase activity
Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.
Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate.
Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + diphosphate.
geranylgeranyl pyrophosphate synthase activity
geranylgeranyl pyrophosphate synthetase activity
geranylgeranyl-diphosphate synthase activity
geranylgeranyl diphosphate synthase activity
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.
Catalysis of the reaction: 2 reduced [2Fe-2S]-[ferredoxin] + NADP+ + H+ = 2 oxidized [2Fe-2S]-[ferredoxin] + NADPH.
Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX.
protoheme ferro-lyase (protoporphyrin-forming)
Catalysis of the reaction: beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.
Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H+.
Catalysis of the reaction: (2E)-geranyl diphosphate + isopentenyl diphosphate = (2E,6E)-farnesyl diphosphate + diphosphate.
farnesyl pyrophosphate synthetase activity
(2E,6E)-farnesyl diphosphate synthase activity
Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.
Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate.
Catalysis of the reaction: D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4.
glucosamine-6-phosphate deaminase activity
Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
D-glucose 6-phosphate dehydrogenase activity
NADP-dependent glucose 6-phosphate dehydrogenase activity
NADP-glucose-6-phosphate dehydrogenase activity
glucose 6-phosphate dehydrogenase (NADP) activity
glucose-6-phosphate 1-dehydrogenase activity
glucose-6-phosphate dehydrogenase activity
Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate.
Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.
Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H+.
Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP+ + phosphate = L-glutamyl 5-phosphate + H+ + NADPH.
glutamate-5-semialdehyde dehydrogenase activity
Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.
Catalysis of the reaction: L-glutamate + NAD+ + H2O = 2-oxoglutarate + NH4+ + NADH + H+.
L-glutamate dehydrogenase (NAD+) activity
Catalysis of the reaction: L-glutamate + NAD(P)+ + H2O = 2-oxoglutarate + NH4+ + NAD(P)H + H+.
L-glutamate:NAD(P)+ oxidoreductase (deaminating)
L-glutamate dehydrogenase [NAD(P)+] activity
Catalysis of the reaction: L-glutamate + NADP+ + H2O = 2-oxoglutarate + NH4+ + NADPH + H+.
L-glutamate dehydrogenase (NADP+) activity
Catalysis of the reaction: ATP + L-glutamate + NH4+ = ADP + H+ + L-glutamine + phosphate.
Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H+ + phosphate.
Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH4+.
Catalysis of the reaction: D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.
glucosamine-6-phosphate isomerase (glutamine-forming) activity
glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L-glutamine:D-fructose-6-phosphate transaminase (isomerizing) activity
Catalysis of the reaction: glutaryl-CoA + 2 H+ + oxidized [electron-transfer flavoprotein] = (2E)-butenoyl-CoA + CO2 + reduced [electron-transfer flavoprotein].
Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H+ + phosphate.
Catalysis of the reaction: RX + glutathione = an S-substituted glutathione + a halide anion + H+.
Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+.
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA.
glycerol-3-phosphate O-acyltransferase activity
Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
glycerol-3-phosphate dehydrogenase (quinone) activity
Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H+.
Catalysis of the reaction: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine.
glycine hydroxymethyltransferase activity
Catalysis of the reaction: [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + H+ + UDP.
alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity
Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H+ = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2.
glycine dehydrogenase (decarboxylating) activity
Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide.
glycylpeptide N-tetradecanoyltransferase activity
Catalysis of the reaction: GDP + H2O = GMP + phosphate.
Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase].
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.
heparan sulfate 2-O-sulfotransferase activity
heparan-sulfate 2-O-sulphotransferase activity
heparan sulfate 2-sulfotransferase activity
Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate.
Catalysis of the reaction: L-histidine = histamine + CO2.
Catalysis of the reaction: L-lysyl-[histone] + acetyl-CoA = N6-acetyl-L-lysyl-[histone] + CoA + H+.
histone lysine acetyltransferase activity
Removal of an acetyl group from a lysine residue in a histone.
histone deacetylase activity (NAD-independent)
Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.
Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH.
hydroxymethylglutaryl-CoA reductase (NADPH) activity
Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+.
hydroxymethylglutaryl-CoA synthase activity
Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.
Catalysis of the reaction: diphosphate + H2O = H+ + 2 phosphate.
inorganic diphosphate phosphatase activity
Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + H+.
1-phosphatidylinositol 4-kinase activity
Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H+.
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity
phosphatidylinositol-4,5-bisphosphate phospholipase C-type activity
phosphatidylinositol-4,5-bisphosphate phospholipase C activity
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-3-phosphate phosphatase activity
Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.
inositol-1,4-bisphosphate 1-phosphatase activity
Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
inositol-polyphosphate 5-phosphatase activity
Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate + phosphate.
inositol hexakisphosphate phosphatase activity
Catalysis of the reaction: isocitrate + NAD(P)+ = 2-oxoglutarate + CO2 + NAD(P)H.
isocitrate dehydrogenase [NAD(P)+] activity
Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH.
NAD dependent isocitrate dehydrogenase activity
NAD-linked isocitrate dehydrogenase activity
NAD-specific isocitrate dehydrogenase activity
isocitrate:NAD+ oxidoreductase (decarboxylating)
nicotinamide adenine dinucleotide isocitrate dehydrogenase activity
isocitrate dehydrogenase (NAD+) activity
Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.
NADP(+)-linked isocitrate dehydrogenase activity
NADP-dependent isocitrate dehydrogenase activity
NADP-dependent isocitric dehydrogenase activity
NADP-linked isocitrate dehydrogenase activity
NADP-specific isocitrate dehydrogenase activity
isocitrate (NADP) dehydrogenase activity
isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
isocitrate dehydrogenase (NADP) activity
isocitrate dehydrogenase (NADP-dependent) activity
isocitrate:NADP+ oxidoreductase (decarboxylating)
triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity
isocitrate dehydrogenase (NADP+) activity
Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone.
Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.
Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.
Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein. May also hydrolyze diacylglycerol and phospholipids present in lipoproteins.
Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
long-chain-fatty-acid-CoA ligase activity
long-chain-fatty-acyl-CoA synthetase activity
long-chain fatty acid-CoA ligase activity
Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.
Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH.
malate dehydrogenase (decarboxylating) (NADP+) activity
Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.
5,10-methenyl-THF cyclohydrolase activity
methenyltetrahydrofolate cyclohydrolase activity
Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.
methionyl-tRNA formyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.
mRNA 5'-cap (guanine-N7-)-methyltransferase activity
Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the first transcribed nucleotide of mRNAs and snRNAs.
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H+ + phosphate.
methylcrotonoyl-CoA carboxylase activity
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD+ = 5,10-methenyltetrahydrofolate + NADH.
methylenetetrahydrofolate dehydrogenase (NAD+) activity
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH.
methylenetetrahydrofolate dehydrogenase (NADP+) activity
Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
5,10-methylenetetrahydrofolate reductase (FADH) activity
5,10-methylenetetrahydrofolate reductase (FADH2) activity
methylenetetrahydrofolate reductase [NAD(P)H] activity
Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + hydrogencarbonate + NADH + H+. Can also use malonate (3-oxopropanoate) as a substrate. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product.
methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H+.
Catalysis of the incorporation of one atom of molecular oxygen (O2) into the substrate and the reduction of the other atom of O2 to water.
Catalysis of the reaction: AH(2) + ecdysone + O2 = 20-hydroxyecdysone + A + H2O.
Catalysis of the reaction: L-kynurenine + H+ + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP+.
Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates.
Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.
Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
Catalysis of the reaction: nicotinate beta-D-ribonucleotide + ATP + H+ = deamido-NAD+ + diphosphate.
ATP:nicotinate-nucleotide adenylyltransferase activity
nicotinate-nucleotide adenylyltransferase activity
Catalysis of the reaction: nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate.
nicotinate phosphoribosyltransferase activity
Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
Catalysis of the cleavage of ester linkages within nucleic acids.
Catalysis of the cleavage of ester linkages within nucleic acids by creating internal breaks.
Catalysis of the cleavage of ester linkages within deoxyribonucleic acid by creating internal breaks.
Catalysis of the cleavage of ester linkages within ribonucleic acid by creating internal breaks.
Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.
Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.
Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.
Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
Catalysis of the endonucleolytic cleavage of DNA to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.
Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule.
Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
Catalysis of the cleavage of ester linkages within deoxyribonucleic acid.
Catalysis of the cleavage of phosphodiester bonds in chains of RNA.
Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.
Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
Catalysis of the reaction: 1-octanol + NAD+ = 1-octanal + H+ + NADH.
Catalysis of the hydrolysis of any O-glycosyl bond.
hydrolase activity, hydrolyzing O-glycosyl compounds
Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.
Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose.
Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.
Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.
Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.
Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.
Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.
Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity
mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity
mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).
mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity
Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid.
Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
asparagine N-glycosyltransferase activity
dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity
dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity
dolichyldiphosphooligosaccharide-protein glycosyltransferase activity
dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity
dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity
dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity
dolichyl-diphosphooligosaccharide-protein glycotransferase activity
Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.