VFB scRNAseq Ontology for dataset FBlc0006423
type: Ontology
description: An ontology of Drosophila melanogaster scRNAseq data from a single dataset (FBlc0006423). This information is taken from FlyBase, which sources it from the EMBL-EBI Single Cell Expression Atlas, which compiles scRNAseq data from multiple sources.

definition
type: AnnotationProperty
IAO_0000111: definition
IAO_0000114: IAO_0000122
definition: A property representing the English language definitions of what NCI means by the concept. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software.
definition: The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
definition: The official definition.
IAO_0000116: 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.
IAO_0000117: PERSON:Daniel Schober
IAO_0000119: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
has exact synonym: DEFINITION
label: textual definition

is a defining property chain axiom
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL

is a defining property chain axiom where second argument is reflexive
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.

database_cross_reference
type: AnnotationProperty
IAO_0000112: disease characteristic (MONDO:0021125) has cross-reference (http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NCIT:C41009"^^xsd:string
definition: An annotation property that links an ontology entity or a statement to a prefixed identifier or URI.
definition: Reference database or publication source.
IAO_0000233: https://github.com/information-artifact-ontology/ontology-metadata/issues/123
contributor: https://orcid.org/0000-0002-7356-1779
label: has cross-reference

part of
type: ObjectProperty
sub property of: overlaps
inverse of: has part
type: TransitiveProperty
IAO_0000111: is part of
IAO_0000112: my brain is part of my body (continuant parthood, two material entities)
IAO_0000112: my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
IAO_0000112: this day is part of this year (occurrent parthood)
definition: a core relation that holds between a part and its whole
IAO_0000116: Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
IAO_0000116: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
IAO_0000116: Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
IAO_0000118: part_of
RO_0001900: RO_0001901
RO_0040042: BFO_0000002
RO_0040042: BFO_0000003
RO_0040042: BFO_0000004
RO_0040042: BFO_0000017
RO_0040042: BFO_0000019
RO_0040042: BFO_0000020
RO_0040042: BFO_0000031
in subset: valid for go annotation extension
in subset: valid for go gp2term
in subset: valid for go ontology
in subset: valid for gocam

has part
type: ObjectProperty
sub property of: overlaps
type: TransitiveProperty
IAO_0000111: has part
IAO_0000112: my body has part my brain (continuant parthood, two material entities)
IAO_0000112: my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
IAO_0000112: this year has part this day (occurrent parthood)
definition: a core relation that holds between a whole and its part
IAO_0000116: Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
IAO_0000116: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
IAO_0000116: Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
IAO_0000118: has_part
RO_0001900: RO_0001901
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

realized in
type: ObjectProperty
inverse of: realizes
domain: BFO_0000017
range: BFO_0000015
IAO_0000111: realized in
IAO_0000112: this disease is realized in this disease course
IAO_0000112: this fragility is realized in this shattering
IAO_0000112: this investigator role is realized in this investigation
IAO_0000118: is realized by
IAO_0000118: realized_in
IAO_0000600: [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

realizes
type: ObjectProperty
domain: BFO_0000015
range: BFO_0000017
IAO_0000111: realizes
IAO_0000112: this disease course realizes this disease
IAO_0000112: this investigation realizes this investigator role
IAO_0000112: this shattering realizes this fragility
definition: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process
IAO_0000600: to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

preceded by
type: ObjectProperty
sub property of: ends after
inverse of: precedes
type: TransitiveProperty
domain: BFO_0000003
range: BFO_0000003
property chain axiom: part of
property chain axiom: starts during
property chain axiom: happens during
IAO_0000111: preceded by
definition: x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
IAO_0000116: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
IAO_0000118: is preceded by
IAO_0000118: preceded_by
source: http://www.obofoundry.org/ro/#OBO_REL:preceded_by
in subset: ro-eco

precedes
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
domain: BFO_0000003
range: BFO_0000003
property chain axiom: part of
property chain axiom: happens during
IAO_0000111: precedes
definition: x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
in subset: ro-eco

substage of
type: ObjectProperty
sub property of: occurrent part of
sub property of: happens during
type: TransitiveProperty
definition: A relation between a developmental stage and another, larger developmental stage during which it happens.
has OBO namespace: relationship
id: FBdv:00018001
comment: Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO.

Axiom
annotated source: substage of
annotated property: definition
annotated target: A relation between a developmental stage and another, larger developmental stage during which it happens.
database_cross_reference: FBC:DPG

has specified input
type: ObjectProperty
sub property of: has participant
inverse of: is specified input of
domain: OBI_0000011
IAO_0000111: has specified input
IAO_0000112: see is_input_of example_of_usage
IAO_0000114: IAO_0000122
definition: The inverse property of is specified input of
IAO_0000116: 8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works.
IAO_0000117: PERSON: Alan Ruttenberg
IAO_0000117: PERSON: Bjoern Peters
IAO_0000117: PERSON: Larry Hunter
IAO_0000117: PERSON: Melanie Coutot

is specified input of
type: ObjectProperty
sub property of: participates in
range: OBI_0000011
IAO_0000111: is specified input of
IAO_0000112: some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay
IAO_0000114: IAO_0000122
definition: A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
IAO_0000117: Alan Ruttenberg
IAO_0000117: PERSON:Bjoern Peters

has specified output
type: ObjectProperty
sub property of: has participant
inverse of: is specified output of
domain: OBI_0000011
IAO_0000111: has specified output
IAO_0000114: IAO_0000122
definition: The inverse property of is specified output of
IAO_0000117: PERSON: Alan Ruttenberg
IAO_0000117: PERSON: Bjoern Peters
IAO_0000117: PERSON: Larry Hunter
IAO_0000117: PERSON: Melanie Courtot

is specified output of
type: ObjectProperty
sub property of: participates in
range: OBI_0000011
IAO_0000111: is specified output of
IAO_0000114: IAO_0000122
definition: A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
IAO_0000117: Alan Ruttenberg
IAO_0000117: PERSON:Bjoern Peters

achieves_planned_objective
type: ObjectProperty
inverse of: objective_achieved_by
domain: OBI_0000011
range: IAO_0000005
IAO_0000111: achieves_planned_objective
IAO_0000112: A cell sorting process achieves the objective specification 'material separation objective'
IAO_0000114: IAO_0000120
definition: This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.
IAO_0000117: BP, AR, PPPB branch
IAO_0000119: PPPB branch derived
IAO_0000232: modified according to email thread from 1/23/09 in accordince with DT and PPPB branch

objective_achieved_by
type: ObjectProperty
domain: IAO_0000005
range: OBI_0000011
IAO_0000111: objective_achieved_by
IAO_0000114: IAO_0000122
definition: This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
IAO_0000117: OBI
IAO_0000119: OBI

characteristic of
type: ObjectProperty
sub property of: characteristic of part of
inverse of: has characteristic
type: FunctionalProperty
IAO_0000111: inheres in
IAO_0000112: this fragility is a characteristic of this vase
IAO_0000112: this red color is a characteristic of this apple
definition: a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
IAO_0000118: inheres_in
RO_0001900: RO_0001901
comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.

has characteristic
type: ObjectProperty
type: InverseFunctionalProperty
range: BFO_0000020
IAO_0000111: bearer of
IAO_0000112: this apple is bearer of this red color
IAO_0000112: this vase is bearer of this fragility
definition: Inverse of characteristic_of
IAO_0000116: A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
IAO_0000118: bearer_of
IAO_0000118: is bearer of
RO_0001900: RO_0001901

participates in
type: ObjectProperty
inverse of: has participant
domain: BFO_0000002
range: BFO_0000003
IAO_0000111: participates in
IAO_0000112: this blood clot participates in this blood coagulation
IAO_0000112: this input material (or this output material) participates in this process
IAO_0000112: this investigator participates in this investigation
definition: a relation between a continuant and a process, in which the continuant is somehow involved in the process
IAO_0000118: participates_in

has participant
type: ObjectProperty
domain: BFO_0000003
range: BFO_0000002
property chain axiom: has part
property chain axiom: realizes
property chain axiom: characteristic of
IAO_0000111: has participant
IAO_0000112: this blood coagulation has participant this blood clot
IAO_0000112: this investigation has participant this investigator
IAO_0000112: this process has participant this input material (or this output material)
definition: a relation between a process and a continuant, in which the continuant is somehow involved in the process
IAO_0000116: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
IAO_0000118: has_participant
source: http://www.obofoundry.org/ro/#OBO_REL:has_participant

is concretized as
type: ObjectProperty
inverse of: concretizes
domain: BFO_0000031
range: Class
  union of: BFO_0000015
  union of: BFO_0000020
IAO_0000112: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
IAO_0000112: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a generically dependent continuant and a specifically dependent continuant or process, in which the generically dependent continuant depends on some independent continuant or process in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants or processes.

concretizes
type: ObjectProperty
domain: Class
  union of: BFO_0000015
  union of: BFO_0000020
range: BFO_0000031
IAO_0000112: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
IAO_0000112: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a specifically dependent continuant or process and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. Multiple specifically dependent continuants or processes can concretize the same generically dependent continuant.

role of
type: ObjectProperty
sub property of: characteristic of
inverse of: has role
IAO_0000112: this investigator role is a role of this person
definition: a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
IAO_0000116: A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.
IAO_0000118: is role of
IAO_0000118: role_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

has role
type: ObjectProperty
sub property of: has characteristic
domain: BFO_0000004
range: BFO_0000023
IAO_0000112: this person has role this investigator role (more colloquially: this person has this role of investigator)
definition: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
IAO_0000116: A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
IAO_0000118: has_role

electrically_synapsed_to
type: ObjectProperty
sub property of: connected to
definition: A relation that holds between two neurons that are electrically coupled via gap junctions.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

innervated by
type: ObjectProperty
inverse of: innervates
domain: UBERON_0000061
range: UBERON_0000122
definition: relation between an anatomical structure and a neuron projection bundle that has synaptic terminals in the structure.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

has synaptic terminal of
type: ObjectProperty
sub property of: overlaps
inverse of: has synaptic terminal in
IAO_0000117: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

occurrent part of
type: ObjectProperty
sub property of: part of
sub property of: causally upstream of or within
domain: BFO_0000003
range: BFO_0000003
definition: A part of relation that applies only between occurrents.

during which ends
type: ObjectProperty
sub property of: temporally related to
inverse of: ends during
IAO_0000117: https://orcid.org/0000-0002-7073-9172
in subset: ro-eco
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

encompasses
type: ObjectProperty
sub property of: during which starts
inverse of: happens during
type: TransitiveProperty
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: di
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

ends after
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
property chain axiom: ends during
property chain axiom: preceded by
IAO_0000117: https://orcid.org/0000-0002-7073-9172
in subset: ro-eco
comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)

immediately preceded by
type: ObjectProperty
sub property of: preceded by
inverse of: immediately precedes
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: starts_at_end_of
comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)

during which starts
type: ObjectProperty
sub property of: temporally related to
inverse of: starts during
IAO_0000117: https://orcid.org/0000-0002-7073-9172
in subset: ro-eco
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

immediately precedes
type: ObjectProperty
sub property of: precedes
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: ends_at_start_of
IAO_0000118: meets
RO_0002575: precedes
in subset: ro-eco
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)

starts during
type: ObjectProperty
sub property of: temporally related to
domain: BFO_0000003
range: BFO_0000003
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: io
in subset: ro-eco
comment: X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))

happens during
type: ObjectProperty
sub property of: starts during
sub property of: ends during
type: TransitiveProperty
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: d
IAO_0000118: during
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
in subset: ro-eco
comment: X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))

ends during
type: ObjectProperty
sub property of: temporally related to
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: o
IAO_0000118: overlaps
in subset: ro-eco
comment: X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y).

has soma location
type: ObjectProperty
sub property of: overlaps
domain: CL_0000540
range: UBERON_0000465
property chain axiom: part of
property chain axiom: is neuron
property chain axiom: is anatomical entity
IAO_0000114: IAO_0000125
definition: Relation between a neuron and a material anatomical entity that its soma is part of.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0043025> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)
RO_0001900: RO_0001901

fasciculates with
type: ObjectProperty
sub property of: overlaps
inverse of: has fasciculating neuron projection
domain: CL_0000540
range: UBERON_0000122
IAO_0000114: IAO_0000125
definition: relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: fasciculates with
IAO_0000426: (forall (?x ?y) (iff (fasciculates_with ?x ?y) (exists (?nps ?npbs) (and ("neuron ; CL_0000540" ?x) ("neuron projection bundle ; CARO_0001001" ?y) ("neuron projection segment ; CARO_0001502" ?nps) ("neuron projection bundle segment ; CARO_0001500' " ?npbs) (part_of ?npbs ?y) (part_of ?nps ?x) (part_of ?nps ?npbs) (forall (?npbss) (if (and ("neuron projection bundle subsegment ; CARO_0001501" ?npbss) (part_of ?npbss ?npbs) ) (overlaps ?nps ?npbss) ))))))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

synapsed by
type: ObjectProperty
sub property of: receives input from
inverse of: synapsed to
range: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
IAO_0000114: IAO_0000125
definition: Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that has_part some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

has postsynaptic terminal in
type: ObjectProperty
sub property of: has synaptic terminal in
inverse of: has presynaptic terminal in
domain: CL_0000540
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: synapsed in
IAO_0000424: http://purl.obolibrary.org/obo/BFO_0000051 some ( http://purl.org/obo/owl/GO#GO_0045211 and http://purl.obolibrary.org/obo/BFO_0000050 some ( http://purl.org/obo/owl/GO#GO_0045202 and http://purl.obolibrary.org/obo/BFO_0000050 some ?Y))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

has presynaptic terminal in
type: ObjectProperty
sub property of: has synaptic terminal in
domain: CL_0000540
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.
IAO_0000118: synapses in
IAO_0000424: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

synapsed to
type: ObjectProperty
sub property of: sends output to
domain: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
IAO_0000114: IAO_0000125
definition: Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: N1 synapsed_to some N2 Expands to: N1 SubclassOf ( has_part some ( ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( ‘synapse ; GO:0045202’ that has_part some ( ‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))

has synaptic terminal in
type: ObjectProperty
sub property of: overlaps
domain: CL_0000540
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: has synapse in
IAO_0000424: <http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

overlaps
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
property chain axiom: part of
property chain axiom: has part
IAO_0000114: IAO_0000125
definition: x overlaps y if and only if there exists some z such that x has part z and z part of y
IAO_0000424: http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)
RO_0001900: RO_0001901
in subset: valid for go annotation extension
in subset: valid for gocam
in subset: ro-eco

Axiom
annotated source: overlaps
annotated property: propertyChainAxiom
annotated target: has part
annotated target: part of
RO_0002582: true

has fasciculating neuron projection
type: ObjectProperty
sub property of: overlaps
domain: UBERON_0000122
range: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
IAO_0000114: IAO_0000125
definition: The relation between a neuron projection bundle and a neuron projection that is fasciculated with it.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: has fasciculating component
IAO_0000426: (forall (?x ?y) (iff (has_fasciculating_neuron_projection ?x ?y) (exists (?nps ?npbs) (and ("neuron projection bundle ; CARO_0001001" ?x) ("neuron projection ; GO0043005" ?y) ("neuron projection segment ; CARO_0001502" ?nps) ("neuron projection bundle segment ; CARO_0001500" ?npbs) (part_of ?nps ?y) (part_of ?npbs ?x) (part_of ?nps ?npbs) (forall (?npbss) (if (and ("neuron projection bundle subsegment ; CARO_0001501" ?npbss) (part_of ?npbss ?npbs) ) (overlaps ?nps ?npbss) ))))))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

innervates
type: ObjectProperty
domain: UBERON_0000122
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

continuous with
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
domain: BFO_0000004
range: BFO_0000004
IAO_0000114: IAO_0000125
definition: X continuous_with Y if and only if X and Y share a fiat boundary.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: connected to
IAO_0000232: The label for this relation was previously connected to. I relabeled this to "continuous with". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)
RO_0001900: RO_0001901

connected to
type: ObjectProperty
sub property of: mereotopologically related to
domain: Restriction
  on property: part of
  some values from: RO_0002577
range: Restriction
  on property: part of
  some values from: RO_0002577
IAO_0000112: a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
definition: a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/22293552

attached to part of
type: ObjectProperty
sub property of: mereotopologically related to
sub property of: biomechanically related to
domain: UBERON_0000061
range: UBERON_0000061
property chain axiom: attached to
property chain axiom: part of
definition: a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.
IAO_0000589: attached to part of (anatomical structure to anatomical structure)

Axiom
annotated source: attached to part of
annotated property: propertyChainAxiom
annotated target: attached to
annotated target: part of
RO_0002582: true

develops from
type: ObjectProperty
sub property of: has developmental contribution from
sub property of: developmentally preceded by
inverse of: develops into
type: TransitiveProperty
domain: BFO_0000004
range: BFO_0000004
IAO_0000114: IAO_0000125
definition: x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y
IAO_0000117: https://orcid.org/0000-0001-9114-8737
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: https://orcid.org/0000-0003-1980-3228
comment: This is the transitive form of the develops from relation

develops into
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to develop into
sub property of: has potential to directly develop into
type: TransitiveProperty
IAO_0000114: IAO_0000125
definition: inverse of develops from
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: https://orcid.org/0000-0003-1980-3228
in subset: RO_0002259

expressed in
type: ObjectProperty
sub property of: genomically related to
inverse of: expresses
domain: BFO_0000002
domain: Class
  union of: BFO_0000031
  union of: BFO_0000040
range: UBERON_0000465
property chain axiom: part of
IAO_0000112: 'neural crest cell' SubClassOf expresses some 'Wnt1 gene'
IAO_0000114: IAO_0000125
definition: x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process
IAO_0000117: https://orcid.org/0000-0002-6601-2165

capable of
type: ObjectProperty
sub property of: capable of part of
domain: BFO_0000004
range: BFO_0000015
IAO_0000112: mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)
IAO_0000112: osteoclast SubClassOf 'capable of' some 'bone resorption'
definition: A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has function realized in
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20123131
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/21208450
IAO_0000232: For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".
in subset: ro-eco

capable of part of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: part of
definition: c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has function in

Axiom
annotated source: capable of part of
annotated property: propertyChainAxiom
annotated target: capable of
annotated target: part of
RO_0002582: true

temporally related to
type: ObjectProperty
domain: BFO_0000003
range: BFO_0000003
IAO_0000114: IAO_0000125
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: Allen's interval algebra
IAO_0000232: Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.
source: https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit
in subset: ro-eco
comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.

develops from part of
type: ObjectProperty
sub property of: develops from
IAO_0000114: IAO_0000125
definition: x develops from part of y if and only if there exists some z such that x develops from z and z is part of y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has input
type: ObjectProperty
sub property of: has participant
inverse of: input of
domain: BFO_0000015
IAO_0000114: IAO_0000125
definition: p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: consumes
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
in subset: ro-eco

has developmental contribution from
type: ObjectProperty
sub property of: developmentally preceded by
inverse of: developmentally contributes to
domain: UBERON_0001062
range: UBERON_0001062
property chain axiom: has part
IAO_0000112: Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]
IAO_0000114: IAO_0000125
definition: x has developmental contribution from y iff x has some part z such that z develops from y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

developmentally contributes to
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to developmentally contribute to
property chain axiom: develops into
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: inverse of has developmental contribution from
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: RO_0002259

developmentally preceded by
type: ObjectProperty
sub property of: developmentally related to
inverse of: developmentally succeeded by
domain: BFO_0000002
range: BFO_0000002
IAO_0000114: IAO_0000125
definition: Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p
IAO_0000116: false
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: In general you should not use this relation to make assertions - use one of the more specific relations below this one
comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from

developmentally succeeded by
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000125
definition: Inverse of developmentally preceded by
IAO_0000117: https://orcid.org/0000-0002-6601-2165

expresses
type: ObjectProperty
sub property of: genomically related to
IAO_0000114: IAO_0000125
definition: y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process.
IAO_0000117: https://orcid.org/0000-0002-6601-2165

characteristic of part of
type: ObjectProperty
sub property of: depends on
property chain axiom: characteristic of
property chain axiom: part of
definition: q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
IAO_0000116: Because part_of is transitive, inheres in is a sub-relation of characteristic of part of
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: inheres in part of
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20064205
RO_0001900: RO_0001901

Axiom
annotated source: characteristic of part of
annotated property: propertyChainAxiom
annotated target: characteristic of
annotated target: part of
RO_0002582: true

mereotopologically related to
type: ObjectProperty
definition: A mereological relationship or a topological relationship
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships
RO_0001900: RO_0001901

developmentally related to
type: ObjectProperty
definition: A relationship that holds between entities participating in some developmental process (GO:0032502)
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development

functionally related to
type: ObjectProperty
definition: A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: This is a grouping relation that collects relations used for the purpose of connecting structure and function

part of structure that is capable of
type: ObjectProperty
sub property of: functionally related to
property chain axiom: part of
property chain axiom: capable of
definition: this relation holds between c and p when c is part of some c', and c' is capable of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: false

Axiom
annotated source: part of structure that is capable of
annotated property: propertyChainAxiom
annotated target: part of
annotated target: capable of
is a defining property chain axiom: true

genomically related to
type: ObjectProperty
domain: BFO_0000002
range: BFO_0000002
definition: holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism

related via localization to
type: ObjectProperty
domain: BFO_0000015
range: BFO_0000002
definition: A relationship that holds via some process of localization
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is a grouping relation.

has target end location
type: ObjectProperty
sub property of: results in transport to from or in
property chain axiom: part of
definition: This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

results in transport to from or in
type: ObjectProperty
sub property of: related via localization to
IAO_0000112: 'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)
IAO_0000117: https://orcid.org/0000-0002-6601-2165

member of
type: ObjectProperty
sub property of: part of
inverse of: has member
IAO_0000112: An organism that is a member of a population of organisms
definition: is member of is a mereological relation between a item and a collection.
IAO_0000118: is member of
IAO_0000118: member part of
IAO_0000119: SIO
RO_0001900: RO_0001901

has member
type: ObjectProperty
sub property of: has part
type: IrreflexiveProperty
definition: has member is a mereological relation between a collection and an item.
IAO_0000119: SIO
RO_0001900: RO_0001901

input of
type: ObjectProperty
sub property of: participates in
sub property of: functionally related to
definition: inverse of has input
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: RO_0002259
in subset: ro-eco

has dendrite location
type: ObjectProperty
sub property of: overlaps
IAO_0000117: https://orcid.org/0000-0002-6601-2165
source: http://neurolex.org/wiki/Property:DendriteLocation

attached to
type: ObjectProperty
sub property of: connected to
sub property of: attached to part of
type: SymmetricProperty
definition: a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000589: attached to (anatomical structure to anatomical structure)
in subset: ro-eco

has developmental potential involving
type: ObjectProperty
sub property of: developmentally related to
domain: UBERON_0001062
range: UBERON_0001062
IAO_0000114: IAO_0000428
definition: x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to developmentally contribute to
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to develop into
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has the potential to develop into y iff x develops into y or if x is capable of developing into y
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: This relation has a stronger meaning than merely indicating that X may develop into Y, in that the capability of developing into Y is always present, even if X does not always actually develop into Y. In particular, this means that if Y is restricted to a given taxon T, X is necessarily likewise restricted.

has potential to directly develop into
type: ObjectProperty
sub property of: has potential to develop into
IAO_0000114: IAO_0000428
definition: x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causally related to
type: ObjectProperty
definition: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
IAO_0000116: This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yie…
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

Axiom
annotated source: causally related to
annotated property: definition
annotated target: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
database_cross_reference: https://en.wikipedia.org/wiki/Causality

causally upstream of or within
type: ObjectProperty
sub property of: causal relation between processes
inverse of: causally downstream of or within
type: TransitiveProperty
property chain axiom: part of
definition: p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
IAO_0000116: We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: influences (processual)
has related synonym: affects

causally downstream of or within
type: ObjectProperty
sub property of: causal relation between processes
type: TransitiveProperty
definition: inverse of causally upstream of or within
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
in subset: RO_0002259

composed primarily of
type: ObjectProperty
sub property of: has part
domain: BFO_0000040
range: BFO_0000040
IAO_0000112: 'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'
definition: x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/22293552
RO_0001900: RO_0001901
in subset: ro-eco

receives input from
type: ObjectProperty
sub property of: connected to
inverse of: sends output to
IAO_0000116: See notes for inverse relation
IAO_0000117: https://orcid.org/0000-0002-6601-2165

sends output to
type: ObjectProperty
sub property of: connected to
IAO_0000116: This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in.
IAO_0000117: https://orcid.org/0000-0002-6601-2165

relation between physical entity and a process or stage
type: ObjectProperty
domain: BFO_0000004
range: BFO_0000003
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage.

existence overlaps
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
definition: x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

causal agent in process
type: ObjectProperty
sub property of: causal relation between material entity and a process
inverse of: process has causal agent
definition: A relationship between a material entity and a process where the material entity has some causal role that influences the process
IAO_0000119: causal-relations

causal relation between processes
type: ObjectProperty
sub property of: causally related to
domain: BFO_0000003
range: BFO_0000003
definition: p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

depends on
type: ObjectProperty
IAO_0000117: https://orcid.org/0000-0002-6601-2165

biomechanically related to
type: ObjectProperty
sub property of: functionally related to
domain: UBERON_0000061
range: UBERON_0000061
definition: A relation that holds between elements of a musculoskeletal system or its analogs.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes.

has part structure that is capable of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal relation between material entity and a process
property chain axiom: has part
property chain axiom: capable of
IAO_0000112: gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'
definition: s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causal relation between material entity and a process
type: ObjectProperty
sub property of: causally related to
domain: BFO_0000040
range: BFO_0000015
definition: A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
IAO_0000116: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations

process has causal agent
type: ObjectProperty
sub property of: causally related to
definition: Inverse of 'causal agent in process'
IAO_0000119: causal-relations

generically depends on
type: ObjectProperty
inverse of: is carrier of
domain: BFO_0000031
range: BFO_0000004
property chain axiom: characteristic of
property chain axiom: is concretized as
IAO_0000112: Genetic information generically depend on molecules of DNA.
IAO_0000112: The novel *War and Peace* generically depends on this copy of the novel.
IAO_0000112: The pattern shared by chess boards generically depends on any chess board.
IAO_0000112: The score of a symphony g-depends on a copy of the score.
IAO_0000112: This pdf file generically depends on this server.
definition: A generically dependent continuant *b* generically depends on an independent continuant *c* at time *t* means: there inheres in *c* a specifically deendent continuant which concretizes *b* at *t*.
IAO_0000119: [072-ISO]
has exact synonym: g-depends on

is carrier of
type: ObjectProperty
domain: BFO_0000004
range: BFO_0000031
property chain axiom: concretizes
property chain axiom: has characteristic
IAO_0000112: Molecules of DNA are carriers of genetic information.
IAO_0000112: This copy of *War and Peace* is carrier of the novel written by Tolstoy.
IAO_0000112: This hard drive is carrier of these data items.
definition: *b* is carrier of *c* at time *t* if and only if *c* *g-depends on* *b* at *t*
IAO_0000119: [072-ISO]

has synaptic IO in region
type: ObjectProperty
sub property of: has synaptic terminal in
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:26:52Z
has exact synonym: has synaptic input or output in

receives synaptic input in region
type: ObjectProperty
sub property of: has postsynaptic terminal in
sub property of: has synaptic IO in region
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:42:23Z

sends synaptic output to region
type: ObjectProperty
sub property of: has presynaptic terminal in
sub property of: has synaptic IO in region
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of output synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:45:06Z

has synaptic IO throughout
type: ObjectProperty
sub property of: has synaptic IO in region
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses distributed throughout that region (rather than confined to a subregion).
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:52:19Z

sends synaptic output throughout
type: ObjectProperty
sub property of: sends synaptic output to region
sub property of: has synaptic IO throughout
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number output synapses distributed throughout that region (rather than confined to a subregion).
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:57:27Z

has sensory dendrite in
type: ObjectProperty
sub property of: has dendrite location
domain: CL_0000101
property chain axiom: part of
definition: Relation between a sensory neuron and some structure in which it receives sensory input via a sensory dendrite.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-20T12:10:09Z
has exact synonym: has sensory dendrite location
has exact synonym: has sensory terminal in
has exact synonym: has sensory terminal location

receives synaptic input from neuron
type: ObjectProperty
sub property of: synapsed by
inverse of: sends synaptic output to cell
definition: A relationship between an anatomical structure (including cells) and a neuron that has a functionally relevant number of chemical synapses to it.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2021-05-26T08:40:18Z

sends synaptic output to cell
type: ObjectProperty
sub property of: synapsed to
definition: A relationship between a neuron and a cell that it has a functionally relevant number of chemical synapses to.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2021-05-26T08:41:07Z
comment: Not restricting range to 'cell' - object may be a muscle containing a cell targeted by the neuron.

synapses restricted to region
type: ObjectProperty
sub property of: has synaptic IO in region
property chain axiom: part of
IAO_0000112: An optic lobe intrinsic neuron has its synapses restricted to optic lobe neuropil.
definition: A relationship between a neuron and a region, where all of the functionally relevant input and output synapses are in that region.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-08-17T12:17:24Z
has exact synonym: intrinsic to
comment: This relation may still be used if a very small number of synapses fall slightly outside the boundaries of the region, but any class using this relation should not have another restriction using this relation to another non-overlapping region.

device utilizes material
type: ObjectProperty
property chain axiom: capable of
property chain axiom: has input
IAO_0000112: A diagnostic testing device utilizes a specimen.
definition: X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.
IAO_0000232: A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input.
IAO_0000232: See github ticket https://github.com/oborel/obo-relations/issues/497
contributor: https://orcid.org/0000-0001-9625-1899
contributor: https://orcid.org/0000-0003-2620-0345
creation date: 2021-11-08T12:00:00Z
has broad synonym: utilizes

is neuron
type: ObjectProperty
domain: CL_0000540
definition: This property only applies to neurons
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-10-23T14:34:52Z

is anatomical entity
type: ObjectProperty
domain: UBERON_0001062
definition: This property only applies to anatomical entities.
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-10-29T09:55:07Z

has assay method
type: ObjectProperty
sub property of: topObjectProperty
inverse of: is assay method of

is assay method of
type: ObjectProperty
sub property of: topObjectProperty

CL_0000540
type: Class
equivalent class: Restriction
  on property: is neuron
  has self: true

germ layer derivative
type: Class
equivalent class: Class
  intersection of: FBbt_10000000
  intersection of: Restriction
    on property: develops from
    some values from: germ layer
subclass of: FBbt_10000000
subclass of: Restriction
  on property: develops from
  some values from: germ layer
definition: Any anatomical entity (FBbt:10000000) that develops from some germ layer (FBbt:00000110).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000000
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: germ layer derivative
annotated property: definition
annotated target: Any anatomical entity (FBbt:10000000) that develops from some germ layer (FBbt:00000110).
database_cross_reference: FlyBase:FBrf0043441
database_cross_reference: FlyBase:FBrf0053832

organism
type: Class
subclass of: FBbt_00100313
definition: An individual member of the species Drosophila melanogaster.
database_cross_reference: CARO:0000012
database_cross_reference: NCBITaxon:7227
database_cross_reference: UBERON:0000468
has OBO namespace: fly_anatomy.ontology
has related synonym: Drosophila
has related synonym: whole organism
id: FBbt:00000001
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: organism
annotated property: definition
annotated target: An individual member of the species Drosophila melanogaster.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

tagma
type: Class
subclass of: FBbt_00057001
subclass of: Restriction
  on property: part of
  some values from: organism
definition: One of the three main divisions of the whole organism formed from groups of segments.
database_cross_reference: UBERON:6000002
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000002
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: tagma
annotated property: definition
annotated target: One of the three main divisions of the whole organism formed from groups of segments.
database_cross_reference: FBC:GG

segment
type: Class
subclass of: FBbt_00057001
definition: One of the repeated divisions of the whole organism.
database_cross_reference: UBERON:0000914
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000003
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: segment
annotated property: definition
annotated target: One of the repeated divisions of the whole organism.
database_cross_reference: FBC:GG

head
type: Class
subclass of: tagma
definition: Anterior part of the organism, including mouthparts, some sensory structures and the brain.
database_cross_reference: UBERON:6000004
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000004
in subset: cur
in subset: larval OF

Axiom
annotated source: head
annotated property: definition
annotated target: Anterior part of the organism, including mouthparts, some sensory structures and the brain.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

ocular segment
type: Class
subclass of: procephalic segment
definition: Head segment derived from the second embryonic segment (between the labral and antennal segments). In the larva, this segment includes Bolwig's organ.
database_cross_reference: UBERON:6000005
has OBO namespace: fly_anatomy.ontology
has related synonym: acron
id: FBbt:00000005
in subset: cur
comment: While classically this structure is not considered to be a segment, but rather to be the non-segmental acron - anterior to the first segment, this ontology follows Schmidt-Ott and colleagues (Schmidt-Ott et al., 1994, and Schmidt-Ott and Technau, 1992) in considering it to be the second segment (posterior to the labral segment in the segmenting embryo). This is based on relating gene expression in the early segmenting embryo to the effects of loss of function mutations of these genes on formation of larval head structures.

Axiom
annotated source: ocular segment
annotated property: definition
annotated target: Head segment derived from the second embryonic segment (between the labral and antennal segments). In the larva, this segment includes Bolwig's organ.
database_cross_reference: FlyBase:FBrf0055841
database_cross_reference: FlyBase:FBrf0075072

head segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: part of
    some values from: head
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: head
definition: Any segment (FBbt:00000003) that is part of some head (FBbt:00000004).
database_cross_reference: UBERON:6000006
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000006
in subset: cur
in subset: larval OF

Axiom
annotated source: head segment
annotated property: definition
annotated target: Any segment (FBbt:00000003) that is part of some head (FBbt:00000004).
database_cross_reference: FlyBase:FBrf0075072

procephalic segment
type: Class
subclass of: head segment
definition: A segment that is anterior to the gnathal segments.
database_cross_reference: UBERON:6000007
has exact synonym: pregnathal segment
has exact synonym: preoral segment
has OBO namespace: fly_anatomy.ontology
has related synonym: cephalic segment
has related synonym: procephalon
id: FBbt:00000007
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: procephalic segment
annotated property: definition
annotated target: A segment that is anterior to the gnathal segments.
database_cross_reference: FBC:GG

labral segment
type: Class
subclass of: procephalic segment
definition: Anteriormost procephalic segment, anterior to the ocular segment. In the adult it bears the clypeo-labrum.
database_cross_reference: UBERON:6000008
has OBO namespace: fly_anatomy.ontology
has related synonym: clypeo-labrum
id: FBbt:00000008
in subset: cur

Axiom
annotated source: labral segment
annotated property: definition
annotated target: Anteriormost procephalic segment, anterior to the ocular segment. In the adult it bears the clypeo-labrum.
database_cross_reference: FlyBase:FBrf0055841
database_cross_reference: FlyBase:FBrf0075072
database_cross_reference: FlyBase:FBrf0089570

antennal segment
type: Class
subclass of: procephalic segment
definition: Segment anterior to the intercalary segment. In the adult it bears the antennae.
database_cross_reference: UBERON:6000009
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000009
in subset: cur

Axiom
annotated source: antennal segment
annotated property: definition
annotated target: Segment anterior to the intercalary segment. In the adult it bears the antennae.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

intercalary segment
type: Class
subclass of: procephalic segment
definition: Most posterior of the procephalic segments. Contains the tritocerebrum.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000010
in subset: FB gloss
in subset: cur

Axiom
annotated source: intercalary segment
annotated property: definition
annotated target: Most posterior of the procephalic segments. Contains the tritocerebrum.
database_cross_reference: FlyBase:FBrf0075072
database_cross_reference: FlyBase:FBrf0089570

gnathal segment
type: Class
subclass of: head segment
definition: The head segments that develop posterior to the embryonic/larval mouth.
database_cross_reference: UBERON:6000011
has OBO namespace: fly_anatomy.ontology
has related synonym: postoral segment
id: FBbt:00000011
in subset: FB gloss
in subset: cur

Axiom
annotated source: gnathal segment
annotated property: definition
annotated target: The head segments that develop posterior to the embryonic/larval mouth.
database_cross_reference: FBC:GG

mandibular segment
type: Class
subclass of: gnathal segment
definition: Most anterior of the gnathal segments.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000012
in subset: cur

Axiom
annotated source: mandibular segment
annotated property: definition
annotated target: Most anterior of the gnathal segments.
database_cross_reference: FlyBase:FBrf0089570

maxillary segment
type: Class
subclass of: gnathal segment
definition: Second gnathal segment, between the mandibular and labial segments. In the adult, it has a paired apodeme and a paired appendage, the maxillary palpus.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000013
in subset: cur

Axiom
annotated source: maxillary segment
annotated property: definition
annotated target: Second gnathal segment, between the mandibular and labial segments. In the adult, it has a paired apodeme and a paired appendage, the maxillary palpus.
database_cross_reference: FlyBase:FBrf0007734
database_cross_reference: FlyBase:FBrf0089570

labial segment
type: Class
subclass of: gnathal segment
definition: Most posterior of the gnathal segments. In the adult it bears a pair of fused appendages, the labia, and its ectodermal invaginations give rise to the salivary glands.
database_cross_reference: UBERON:6000014
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000014
in subset: cur

Axiom
annotated source: labial segment
annotated property: definition
annotated target: Most posterior of the gnathal segments. In the adult it bears a pair of fused appendages, the labia, and its ectodermal invaginations give rise to the salivary glands.
database_cross_reference: FlyBase:FBrf0007734

thorax
type: Class
subclass of: tagma
definition: The main middle section of the insect body comprising three thoracic rings: the pro-, the meso- and the metathoraces which are more or less well fused and cask-like sometimes having on the upper lateral part one of two pairs of wings, while on the ventrolateral part each thoracic ring bears a pair of legs.
database_cross_reference: UBERON:6000015
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000015
in subset: FB gloss
in subset: cur

Axiom
annotated source: thorax
annotated property: definition
annotated target: The main middle section of the insect body comprising three thoracic rings: the pro-, the meso- and the metathoraces which are more or less well fused and cask-like sometimes having on the upper lateral part one of two pairs of wings, while on the ventrolateral part each thoracic ring bears a pair of legs.
database_cross_reference: FlyBase:FBrf0166419

thoracic segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: part of
    some values from: thorax
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: thorax
definition: Any segment (FBbt:00000003) that is part of some thorax (FBbt:00000015).
database_cross_reference: UBERON:6000016
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000016
in subset: cur

Axiom
annotated source: thoracic segment
annotated property: definition
annotated target: Any segment (FBbt:00000003) that is part of some thorax (FBbt:00000015).
database_cross_reference: FBC:Autogenerated

prothoracic segment
type: Class
subclass of: thoracic segment
definition: The first (most anterior) segment of the thorax.
database_cross_reference: UBERON:6000017
has OBO namespace: fly_anatomy.ontology
has related synonym: prothorax
has related synonym: t1
has related synonym: thoracic segment 1
id: FBbt:00000017
in subset: cur

Axiom
annotated source: prothoracic segment
annotated property: definition
annotated target: The first (most anterior) segment of the thorax.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

mesothoracic segment
type: Class
subclass of: thoracic segment
definition: The second (middle) segment of the thorax.
database_cross_reference: UBERON:6000018
has OBO namespace: fly_anatomy.ontology
has related synonym: mesothorax
has related synonym: t2
has related synonym: thoracic segment 2
id: FBbt:00000018
in subset: FB gloss
in subset: cur

Axiom
annotated source: mesothoracic segment
annotated property: definition
annotated target: The second (middle) segment of the thorax.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

metathoracic segment
type: Class
subclass of: thoracic segment
definition: The third (most posterior) segment of the thorax.
database_cross_reference: UBERON:6000019
has OBO namespace: fly_anatomy.ontology
has related synonym: metathorax
has related synonym: t3
has related synonym: thoracic segment 3
id: FBbt:00000019
in subset: FB gloss
in subset: cur

Axiom
annotated source: metathoracic segment
annotated property: definition
annotated target: The third (most posterior) segment of the thorax.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

abdomen
type: Class
subclass of: tagma
definition: The most posterior of the three tagma (FBbt:00000002).
database_cross_reference: UBERON:6000020
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000020
in subset: FB gloss
in subset: cur

Axiom
annotated source: abdomen
annotated property: definition
annotated target: The most posterior of the three tagma (FBbt:00000002).
database_cross_reference: FlyBase:FBrf0166419

abdominal segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: part of
    some values from: abdomen
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: abdomen
definition: Metameric subdivision of the abdomen.
database_cross_reference: UBERON:6000021
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000021
in subset: cur

Axiom
annotated source: abdominal segment
annotated property: definition
annotated target: Metameric subdivision of the abdomen.
database_cross_reference: FBC:SPR

abdominal segment 6
type: Class
subclass of: FBbt_00052393
definition: Sixth most anterior segment of the abdomen.
has OBO namespace: fly_anatomy.ontology
has related synonym: a6
id: FBbt:00000027
in subset: cur

Axiom
annotated source: abdominal segment 6
annotated property: definition
annotated target: Sixth most anterior segment of the abdomen.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

abdominal segment 8
type: Class
subclass of: FBbt_00052388
subclass of: Restriction
  on property: overlaps
  some values from: telson
definition: Eighth most anterior segment of the abdomen.
database_cross_reference: UBERON:6000029
has OBO namespace: fly_anatomy.ontology
has related synonym: a8
id: FBbt:00000029
in subset: cur

Axiom
annotated source: abdominal segment 8
annotated property: definition
annotated target: Eighth most anterior segment of the abdomen.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

abdominal segment 9
type: Class
subclass of: FBbt_00052388
subclass of: Restriction
  on property: part of
  some values from: telson
definition: Ninth most anterior segment of the abdomen.
database_cross_reference: UBERON:6000030
has OBO namespace: fly_anatomy.ontology
has related synonym: a9
id: FBbt:00000030
in subset: cur

Axiom
annotated source: abdominal segment 9
annotated property: definition
annotated target: Ninth most anterior segment of the abdomen.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

abdominal segment 11
type: Class
subclass of: FBbt_00052388
subclass of: Restriction
  on property: part of
  some values from: telson
definition: Eleventh most anterior segment of the abdomen.
has OBO namespace: fly_anatomy.ontology
has related synonym: a11
id: FBbt:00000032
in subset: cur

Axiom
annotated source: abdominal segment 11
annotated property: definition
annotated target: Eleventh most anterior segment of the abdomen.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

telson
type: Class
subclass of: FBbt_00057001
subclass of: Restriction
  on property: part of
  some values from: abdomen
definition: Dorsal portion of the eighth segment and all structures posterior to it (Pignoni et al., 1992).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000033
in subset: cur

Axiom
annotated source: telson
annotated property: definition
annotated target: Dorsal portion of the eighth segment and all structures posterior to it (Pignoni et al., 1992).
database_cross_reference: FlyBase:FBrf0055857

egg
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: develops from
  some values from: oocyte
definition: Structure that develops from an oocyte once it has been released from the ovary by ovulation (Qazi et al., 2003). Ovulation triggers egg activation, which alters envelope permeability and causes the resumption of meiosis and translation (Qazi et al., 2003). Fertilization of the egg begins embryogenesis (Loppin et al., 2015).
has exact synonym: ovum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000034
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: egg
annotated property: definition
annotated target: Structure that develops from an oocyte once it has been released from the ovary by ovulation (Qazi et al., 2003). Ovulation triggers egg activation, which alters envelope permeability and causes the resumption of meiosis and translation (Qazi et al., 2003). Fertilization of the egg begins embryogenesis (Loppin et al., 2015).
database_cross_reference: FlyBase:FBrf0158848
database_cross_reference: FlyBase:FBrf0229233

Axiom
annotated source: egg
annotated property: hasExactSynonym
annotated target: ovum
database_cross_reference: FlyBase:FBrf0158848

embryo
type: Class
subclass of: organism
definition: An organism that is undergoing embryogenesis (Campos-Ortega and Hartenstein, 1997). Embryogenesis begins with a fertilized egg, and finishes with hatching at the end of embryonic stage 17 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00005289
database_cross_reference: UBERON:0000922
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000052
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryo
annotated property: definition
annotated target: An organism that is undergoing embryogenesis (Campos-Ortega and Hartenstein, 1997). Embryogenesis begins with a fertilized egg, and finishes with hatching at the end of embryonic stage 17 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0039741
database_cross_reference: FlyBase:FBrf0089570

cleavage stage embryo
type: Class
subclass of: embryo
definition: Embryo that is in the cleavage stage, which encompasses the first 13 rapid divisions after fertilization, corresponding to embryonic stages 1-4, prior to cellularization (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). The first seven divisions are synchronous (Campos-Ortega and Hartenstein, 1997). During the course of the subsequent three divisions, most of the nuclei approach the surface, to form the syncitial blastoderm (Campos-Ortega and Hartenstein, 1997). They then divide asynchronously a further three times, bringing the total number of cells to around 5000 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00000054
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000054

Axiom
annotated source: cleavage stage embryo
annotated property: definition
annotated target: Embryo that is in the cleavage stage, which encompasses the first 13 rapid divisions after fertilization, corresponding to embryonic stages 1-4, prior to cellularization (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). The first seven divisions are synchronous (Campos-Ortega and Hartenstein, 1997). During the course of the subsequent three divisions, most of the nuclei approach the surface, to form the syncitial blastoderm (Campos-Ortega and Hartenstein, 1997). They then divide asynchronously a further three times, bringing the total number of cells to around 5000 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570

pole bud
type: Class
subclass of: cell component
subclass of: Restriction
  on property: part of
  some values from: syncytial blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: pole plasm
definition: Cytoplasmic bud that forms at the posterior pole of the embryo during cycle 9. Pole buds give rise to the pole cells.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000091
in subset: cur

Axiom
annotated source: pole bud
annotated property: definition
annotated target: Cytoplasmic bud that forms at the posterior pole of the embryo during cycle 9. Pole buds give rise to the pole cells.
database_cross_reference: FlyBase:FBrf0064779

primordial germ cell
type: Class
subclass of: germline cell
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053322
subclass of: Restriction
  on property: expresses
  some values from: FBgn0283442
definition: Cell that begins as a pole cell, becomes incorporated into the gonad and can develop into a germline stem cell (Campos-Ortega and Hartenstein, 1997; Dansereau and Lasko, 2008; Slaidina et al., 2020).
has broad synonym: GC
database_cross_reference: CL:0000301
has exact synonym: PGC
has OBO namespace: fly_anatomy.ontology
has related synonym: pole cell
id: FBbt:00000092
in subset: FB gloss
in subset: cur
comment: Can be identified in the larva by expression of vasa (Slaidina et al., 2020). Only a small subset of pole cells can become germ cells and this fate might be specified by the time the posterior midgut primordium invaginates (Okada, 1998).

Axiom
annotated source: primordial germ cell
annotated property: definition
annotated target: Cell that begins as a pole cell, becomes incorporated into the gonad and can develop into a germline stem cell (Campos-Ortega and Hartenstein, 1997; Dansereau and Lasko, 2008; Slaidina et al., 2020).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0101973
database_cross_reference: FlyBase:FBrf0216027
database_cross_reference: FlyBase:FBrf0244767

Axiom
annotated source: primordial germ cell
annotated property: hasBroadSynonym
annotated target: GC
database_cross_reference: FlyBase:FBrf0244767

germ band
type: Class
subclass of: developing embryonic structure
definition: Embryonic collection of cells that will give rise to the metameric regions of the embryo, comprising precursors of the gnathal, thoracic and abdominal segments (Campos-Ortega and Hartenstein, 1997).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000102
in subset: FB gloss
in subset: cur

Axiom
annotated source: germ band
annotated property: definition
annotated target: Embryonic collection of cells that will give rise to the metameric regions of the embryo, comprising precursors of the gnathal, thoracic and abdominal segments (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

mesoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: develops into
  some values from: mesoderm
definition: Contiguous region of early embryonic cells that will invaginate to form the mesoderm during gastrulation (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:6000104
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral plate
id: FBbt:00000104
in subset: cur

Axiom
annotated source: mesoderm anlage
annotated property: definition
annotated target: Contiguous region of early embryonic cells that will invaginate to form the mesoderm during gastrulation (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831

germ layer
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: portion of tissue
subclass of: Restriction
  on property: develops into
  some values from: germ layer derivative
definition: Complex primordium that is formed during gastrulation (stage 6-7), when anlagen invaginate from the monolayer of the cellular blastoderm (Campos-Ortega and Hartenstein, 1997; Hartenstein, 2004). The invaginated anlagen become organized into the middle two layers of a three-layered tube structure (Campos-Ortega and Hartenstein, 1997). These three layers correspond to the three germ layers of the endoderm, mesoderm and ectoderm (from inner to outer, respectively), with each layer having distinct cell division patterns and cell fates (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:0000923
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000110
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur

Axiom
annotated source: germ layer
annotated property: definition
annotated target: Complex primordium that is formed during gastrulation (stage 6-7), when anlagen invaginate from the monolayer of the cellular blastoderm (Campos-Ortega and Hartenstein, 1997; Hartenstein, 2004). The invaginated anlagen become organized into the middle two layers of a three-layered tube structure (Campos-Ortega and Hartenstein, 1997). These three layers correspond to the three germ layers of the endoderm, mesoderm and ectoderm (from inner to outer, respectively), with each layer having distinct cell division patterns and cell fates (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0178740

ectoderm
type: Class
subclass of: germ layer
subclass of: Restriction
  on property: develops from
  some values from: ectoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00025990
definition: Outermost germ layer of the embryo (Campos-Ortega and Hartenstein, 1997). It is formed from the ectoderm anlage, which includes the cells of the cellular blastoderm monolayer that do not invaginate during gastrulation (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:0000924
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000111
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur

Axiom
annotated source: ectoderm
annotated property: definition
annotated target: Outermost germ layer of the embryo (Campos-Ortega and Hartenstein, 1997). It is formed from the ectoderm anlage, which includes the cells of the cellular blastoderm monolayer that do not invaginate during gastrulation (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0244630

dorsal ectoderm
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: trunk ectoderm
subclass of: Restriction
  on property: develops from
  some values from: dorsal ectoderm anlage
definition: Dorsal region of the ectoderm. It forms parts of the larval epidermis and the tracheal system, with other parts of these contributed to by the lateral ectoderm (Stathopoulos and Newcomb, 2020).
database_cross_reference: UBERON:6000112
has OBO namespace: fly_anatomy.ontology
has related synonym: AdorEc
has related synonym: dorEc
id: FBbt:00000112
in subset: cur

Axiom
annotated source: dorsal ectoderm
annotated property: definition
annotated target: Dorsal region of the ectoderm. It forms parts of the larval epidermis and the tracheal system, with other parts of these contributed to by the lateral ectoderm (Stathopoulos and Newcomb, 2020).
database_cross_reference: FlyBase:FBrf0244630

anterior ectoderm
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: develops from
  some values from: FBbt_01000119
definition: The region of the ectoderm anterior to the cephalic furrow.
database_cross_reference: UBERON:6000119
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000119
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: anterior ectoderm
annotated property: definition
annotated target: The region of the ectoderm anterior to the cephalic furrow.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

early stomodeal invagination
type: Class
subclass of: stomodeal invagination
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
definition: Stomodeal invagination in its initial growth phase during stage 10 as it extends vertically (Campos-Ortega and Hartenstein, 1997).
has exact synonym: stomodeal invagination early
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000120
in subset: cur

Axiom
annotated source: early stomodeal invagination
annotated property: definition
annotated target: Stomodeal invagination in its initial growth phase during stage 10 as it extends vertically (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

posterior ectoderm
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: trunk ectoderm
subclass of: Restriction
  on property: develops from
  some values from: FBbt_01000122
subclass of: Restriction
  on property: develops into
  some values from: hindgut
definition: Region of the ectoderm found posterior to the dorsal, lateral and ventral regions of the ectoderm and anterior to the posterior endoderm (Stathopoulos and Newcomb, 2020). It forms the hindgut (Stathopoulos and Newcomb, 2020).
has exact synonym: proctodeal ring
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000122
in subset: cur

Axiom
annotated source: posterior ectoderm
annotated property: definition
annotated target: Region of the ectoderm found posterior to the dorsal, lateral and ventral regions of the ectoderm and anterior to the posterior endoderm (Stathopoulos and Newcomb, 2020). It forms the hindgut (Stathopoulos and Newcomb, 2020).
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: posterior ectoderm
annotated property: hasExactSynonym
annotated target: proctodeal ring
database_cross_reference: FlyBase:FBrf0244630

amnioproctodeal invagination
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: gastrula embryo
definition: The posterior invagination of ectoderm that gives rise to part of the digestive system.
database_cross_reference: UBERON:0000931
has OBO namespace: fly_anatomy.ontology
has related synonym: posterior midgut invagination
id: FBbt:00000123
in subset: FB gloss
in subset: cur

Axiom
annotated source: amnioproctodeal invagination
annotated property: definition
annotated target: The posterior invagination of ectoderm that gives rise to part of the digestive system.
database_cross_reference: FBC:GG

epithelial cell
type: Class
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: epithelium
definition: Cell that has as its part a cytoskeleton that allows for tight cell to cell contact and which has apical-basal cell polarity.
database_cross_reference: CARO:0000077
database_cross_reference: CL:0000066
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000124
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: epithelial cell
annotated property: definition
annotated target: Cell that has as its part a cytoskeleton that allows for tight cell to cell contact and which has apical-basal cell polarity.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

endoderm
type: Class
subclass of: germ layer
subclass of: Restriction
  on property: develops from
  some values from: endoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00025994
definition: Innermost germ layer of the embryo (Campos-Ortega and Hartenstein, 1997). It is formed by the invagination of two anlagen, those of the anterior and posterior midgut (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:0000925
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000125
in subset: FB gloss
in subset: cur

Axiom
annotated source: endoderm
annotated property: definition
annotated target: Innermost germ layer of the embryo (Campos-Ortega and Hartenstein, 1997). It is formed by the invagination of two anlagen, those of the anterior and posterior midgut (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831

mesoderm
type: Class
subclass of: germ layer
subclass of: Restriction
  on property: develops from
  some values from: mesoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00025998
definition: Middle germ layer of the embryo (between ectoderm and endoderm) following gastrulation (Campos-Ortega and Hartenstein, 1997). Shortly after its formation, its cells undergo mitosis and it loses its regular epithelial architecture (Campos-Ortega and Hartenstein, 1997). In stage 9 it reorganizes into a regular monolayer of cuboidal cells that lines the ectoderm (Campos-Ortega and Hartenstein, 1997). At the end of stage 10 further cell divisions disrupt this structure and its cells reform into two layers in stage 11 (Campos-Ortega and Hartenstein, 1997). It finally splits up into separate cell masses in late stage 11 (Campos-Ortega and Hartenstein, 1997). Its derivatives include the muscles, heart and fat body (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:0000926
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000126
in subset: FB gloss
in subset: cur

Axiom
annotated source: mesoderm
annotated property: definition
annotated target: Middle germ layer of the embryo (between ectoderm and endoderm) following gastrulation (Campos-Ortega and Hartenstein, 1997). Shortly after its formation, its cells undergo mitosis and it loses its regular epithelial architecture (Campos-Ortega and Hartenstein, 1997). In stage 9 it reorganizes into a regular monolayer of cuboidal cells that lines the ectoderm (Campos-Ortega and Hartenstein, 1997). At the end of stage 10 further cell divisions disrupt this structure and its cells reform into two layers in stage 11 (Campos-Ortega and Hartenstein, 1997). It finally splits up into separate cell masses in late stage 11 (Campos-Ortega and Hartenstein, 1997). Its derivatives include the muscles, heart and fat body (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831

trunk mesoderm
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: germ band
subclass of: Restriction
  on property: part of
  some values from: mesoderm
subclass of: Restriction
  on property: develops from
  some values from: trunk mesoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00026000
definition: Region of mesoderm of that forms a layer interior to the ectoderm of the germ band (Campos-Ortega and Hartenstein, 1997). Following its invagination during ventral furrow formation in stages 6 and 7, it remains a coherent structure with no morphologically apparent subdivisions, apart from transient metamery during stage 9, until stage 11 (Campos-Ortega and Hartenstein, 1997). Its cells divide following invagination and it loses its epithelial integrity, forming a monolayer of cuboidal cells by stage 9 (Campos-Ortega and Hartenstein, 1997). A further division happens during stage 10 leading to two distinct layers by stage 11 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:6000128
has exact synonym: mesoderm of the germ layer
has OBO namespace: fly_anatomy.ontology
has related synonym: AtrunkMes
has related synonym: P2 TrMes
has related synonym: TrMes
id: FBbt:00000128
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: trunk mesoderm
annotated property: definition
annotated target: Region of mesoderm of that forms a layer interior to the ectoderm of the germ band (Campos-Ortega and Hartenstein, 1997). Following its invagination during ventral furrow formation in stages 6 and 7, it remains a coherent structure with no morphologically apparent subdivisions, apart from transient metamery during stage 9, until stage 11 (Campos-Ortega and Hartenstein, 1997). Its cells divide following invagination and it loses its epithelial integrity, forming a monolayer of cuboidal cells by stage 9 (Campos-Ortega and Hartenstein, 1997). A further division happens during stage 10 leading to two distinct layers by stage 11 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: trunk mesoderm
annotated property: hasExactSynonym
annotated target: mesoderm of the germ layer
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: trunk mesoderm
annotated property: hasRelatedSynonym
annotated target: P2 TrMes
database_cross_reference: https://orcid.org/0000-0002-7073-9172

somatic trunk mesoderm
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: trunk mesoderm
definition: Outer layer of the trunk mesoderm that arises due to mitosis at the end of stage 10 (Campos-Ortega and Hartenstein, 1997). It will give rise to the segmentally-repeated body wall muscles and the fat body (Campos-Ortega and Hartenstein, 1997).
has OBO namespace: fly_anatomy.ontology
has related synonym: somatopleura
id: FBbt:00000129
in subset: cur

Axiom
annotated source: somatic trunk mesoderm
annotated property: definition
annotated target: Outer layer of the trunk mesoderm that arises due to mitosis at the end of stage 10 (Campos-Ortega and Hartenstein, 1997). It will give rise to the segmentally-repeated body wall muscles and the fat body (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: somatic trunk mesoderm
annotated property: hasRelatedSynonym
annotated target: somatopleura
database_cross_reference: FlyBase:FBrf0089570

visceral trunk mesoderm
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: trunk mesoderm
definition: Inner layer of the trunk mesoderm that arises due to mitosis at the end of stage 10 (Campos-Ortega and Hartenstein, 1997). It will give rise to the visceral musculature of the trunk (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:6000130
has OBO namespace: fly_anatomy.ontology
has related synonym: splanchnopleura
id: FBbt:00000130
in subset: cur

Axiom
annotated source: visceral trunk mesoderm
annotated property: definition
annotated target: Inner layer of the trunk mesoderm that arises due to mitosis at the end of stage 10 (Campos-Ortega and Hartenstein, 1997). It will give rise to the visceral musculature of the trunk (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: visceral trunk mesoderm
annotated property: hasRelatedSynonym
annotated target: splanchnopleura
database_cross_reference: FlyBase:FBrf0089570

embryonic tagma
type: Class
equivalent class: Class
  intersection of: tagma
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: tagma
subclass of: Restriction
  on property: part of
  some values from: embryo
definition: Any tagma of the embryo.
database_cross_reference: UBERON:6000137
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000137
in subset: cur

Axiom
annotated source: embryonic tagma
annotated property: definition
annotated target: Any tagma of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: embryo
definition: Any segment of the embryo.
database_cross_reference: UBERON:6000154
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000154
in subset: cur

Axiom
annotated source: embryonic segment
annotated property: definition
annotated target: Any segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic head
type: Class
equivalent class: Class
  intersection of: head
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: head
subclass of: embryonic tagma
definition: Any head of the embryo.
database_cross_reference: UBERON:0008816
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000155
in subset: cur
in subset: larval OF

Axiom
annotated source: embryonic head
annotated property: definition
annotated target: Any head of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic ocular segment
type: Class
equivalent class: Class
  intersection of: ocular segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: ocular segment
subclass of: embryonic procephalic segment
definition: Any ocular segment of the embryo.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic acron
id: FBbt:00000156
in subset: cur

Axiom
annotated source: embryonic ocular segment
annotated property: definition
annotated target: Any ocular segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic head segment
type: Class
equivalent class: Class
  intersection of: head segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: head segment
subclass of: embryonic segment
subclass of: Restriction
  on property: part of
  some values from: embryonic head
definition: Any head segment of the embryo.
database_cross_reference: UBERON:6000157
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000157
in subset: cur

Axiom
annotated source: embryonic head segment
annotated property: definition
annotated target: Any head segment of the embryo.
database_cross_reference: FlyBase:FBrf0075072

embryonic procephalic segment
type: Class
equivalent class: Class
  intersection of: procephalic segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: procephalic segment
subclass of: embryonic head segment
definition: Any procephalic segment of the embryo.
database_cross_reference: UBERON:6000158
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000158
in subset: cur

Axiom
annotated source: embryonic procephalic segment
annotated property: definition
annotated target: Any procephalic segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic labral segment
type: Class
equivalent class: Class
  intersection of: labral segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: labral segment
subclass of: embryonic procephalic segment
definition: Any labral segment of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000159
in subset: cur

Axiom
annotated source: embryonic labral segment
annotated property: definition
annotated target: Any labral segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic antennal segment
type: Class
equivalent class: Class
  intersection of: antennal segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: antennal segment
subclass of: embryonic procephalic segment
definition: Any antennal segment of the embryo.
database_cross_reference: UBERON:6000160
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000160
in subset: cur

Axiom
annotated source: embryonic antennal segment
annotated property: definition
annotated target: Any antennal segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic intercalary segment
type: Class
equivalent class: Class
  intersection of: intercalary segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: intercalary segment
subclass of: embryonic procephalic segment
definition: Any intercalary segment of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000161
in subset: cur

Axiom
annotated source: embryonic intercalary segment
annotated property: definition
annotated target: Any intercalary segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic gnathal segment
type: Class
equivalent class: Class
  intersection of: gnathal segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: gnathal segment
subclass of: embryonic head segment
definition: Any gnathal segment of the embryo.
database_cross_reference: UBERON:6000162
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000162
in subset: cur

Axiom
annotated source: embryonic gnathal segment
annotated property: definition
annotated target: Any gnathal segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic mandibular segment
type: Class
equivalent class: Class
  intersection of: mandibular segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: mandibular segment
subclass of: embryonic gnathal segment
definition: Any mandibular segment of the embryo.
has exact synonym: mandibular lobe
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000163
in subset: cur

Axiom
annotated source: embryonic mandibular segment
annotated property: definition
annotated target: Any mandibular segment of the embryo.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: embryonic mandibular segment
annotated property: hasExactSynonym
annotated target: mandibular lobe
database_cross_reference: FlyBase:FBrf0051848

embryonic maxillary segment
type: Class
equivalent class: Class
  intersection of: maxillary segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: maxillary segment
subclass of: embryonic gnathal segment
definition: Any maxillary segment of the embryo.
has exact synonym: maxillary lobe
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000164
in subset: cur

Axiom
annotated source: embryonic maxillary segment
annotated property: definition
annotated target: Any maxillary segment of the embryo.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: embryonic maxillary segment
annotated property: hasExactSynonym
annotated target: maxillary lobe
database_cross_reference: FlyBase:FBrf0051848

embryonic labial segment
type: Class
equivalent class: Class
  intersection of: labial segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: labial segment
subclass of: embryonic gnathal segment
definition: Any labial segment of the embryo.
database_cross_reference: UBERON:6000165
has exact synonym: labial lobe
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000165
in subset: cur

Axiom
annotated source: embryonic labial segment
annotated property: definition
annotated target: Any labial segment of the embryo.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: embryonic labial segment
annotated property: hasExactSynonym
annotated target: labial lobe
database_cross_reference: FlyBase:FBrf0051848

embryonic thorax
type: Class
equivalent class: Class
  intersection of: thorax
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: thorax
subclass of: embryonic tagma
definition: Any thorax of the embryo.
database_cross_reference: UBERON:6000166
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000166
in subset: cur

Axiom
annotated source: embryonic thorax
annotated property: definition
annotated target: Any thorax of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic thoracic segment
type: Class
equivalent class: Class
  intersection of: thoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: thoracic segment
subclass of: embryonic segment
subclass of: Restriction
  on property: part of
  some values from: embryonic thorax
definition: Any thoracic segment of the embryo.
database_cross_reference: UBERON:6000167
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000167
in subset: cur

Axiom
annotated source: embryonic thoracic segment
annotated property: definition
annotated target: Any thoracic segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic prothoracic segment
type: Class
equivalent class: Class
  intersection of: prothoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: prothoracic segment
subclass of: embryonic thoracic segment
definition: Prothoracic segment of the embryo.
database_cross_reference: UBERON:6000168
has OBO namespace: fly_anatomy.ontology
has related synonym: prothorax
has related synonym: t1
has related synonym: thoracic segment 1
id: FBbt:00000168
in subset: cur

Axiom
annotated source: embryonic prothoracic segment
annotated property: definition
annotated target: Prothoracic segment of the embryo.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic mesothoracic segment
type: Class
equivalent class: Class
  intersection of: mesothoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: mesothoracic segment
subclass of: embryonic thoracic segment
definition: Mesothoracic segment of the embryo.
database_cross_reference: UBERON:6000169
has OBO namespace: fly_anatomy.ontology
has related synonym: mesothorax
has related synonym: t2
has related synonym: thoracic segment 2
id: FBbt:00000169
in subset: cur

Axiom
annotated source: embryonic mesothoracic segment
annotated property: definition
annotated target: Mesothoracic segment of the embryo.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic metathoracic segment
type: Class
equivalent class: Class
  intersection of: metathoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: metathoracic segment
subclass of: embryonic thoracic segment
definition: Metathoracic segment of the embryo.
database_cross_reference: UBERON:6000170
has OBO namespace: fly_anatomy.ontology
has related synonym: metathorax
has related synonym: t3
has related synonym: thoracic segment 3
id: FBbt:00000170
in subset: cur

Axiom
annotated source: embryonic metathoracic segment
annotated property: definition
annotated target: Metathoracic segment of the embryo.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic abdomen
type: Class
equivalent class: Class
  intersection of: abdomen
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: abdomen
subclass of: embryonic tagma
definition: Abdomen of the embryo.
database_cross_reference: UBERON:6000171
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000171
in subset: cur

Axiom
annotated source: embryonic abdomen
annotated property: definition
annotated target: Abdomen of the embryo.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic abdominal segment
type: Class
equivalent class: Class
  intersection of: abdominal segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: abdominal segment
subclass of: embryonic segment
subclass of: Restriction
  on property: part of
  some values from: embryonic abdomen
definition: Metameric subdivision of the embryonic abdomen.
database_cross_reference: UBERON:6000172
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000172
in subset: cur

Axiom
annotated source: embryonic abdominal segment
annotated property: definition
annotated target: Metameric subdivision of the embryonic abdomen.
database_cross_reference: FBC:SPR

embryonic abdominal segment 6
type: Class
equivalent class: Class
  intersection of: abdominal segment 6
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: abdominal segment 6
subclass of: FBbt_00052394
definition: Any abdominal segment 6 of the embryo.
has OBO namespace: fly_anatomy.ontology
has related synonym: a6
id: FBbt:00000178
in subset: cur

Axiom
annotated source: embryonic abdominal segment 6
annotated property: definition
annotated target: Any abdominal segment 6 of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic abdominal segment 8
type: Class
equivalent class: Class
  intersection of: abdominal segment 8
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: abdominal segment 8
subclass of: FBbt_00052390
subclass of: Restriction
  on property: overlaps
  some values from: embryonic telson
definition: Any abdominal segment 8 of the embryo.
database_cross_reference: UBERON:6000180
has OBO namespace: fly_anatomy.ontology
has related synonym: a8
id: FBbt:00000180
in subset: cur

Axiom
annotated source: embryonic abdominal segment 8
annotated property: definition
annotated target: Any abdominal segment 8 of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic abdominal segment 9
type: Class
equivalent class: Class
  intersection of: abdominal segment 9
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: abdominal segment 9
subclass of: FBbt_00052390
subclass of: Restriction
  on property: part of
  some values from: embryonic telson
definition: Any abdominal segment 9 of the embryo.
database_cross_reference: UBERON:6000181
has OBO namespace: fly_anatomy.ontology
has related synonym: a9
id: FBbt:00000181
in subset: cur

Axiom
annotated source: embryonic abdominal segment 9
annotated property: definition
annotated target: Any abdominal segment 9 of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic abdominal segment 11
type: Class
equivalent class: Class
  intersection of: abdominal segment 11
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: abdominal segment 11
subclass of: FBbt_00052390
subclass of: Restriction
  on property: part of
  some values from: embryonic telson
definition: Any abdominal segment 11 of the embryo.
has OBO namespace: fly_anatomy.ontology
has related synonym: a11
id: FBbt:00000183
in subset: cur

Axiom
annotated source: embryonic abdominal segment 11
annotated property: definition
annotated target: Any abdominal segment 11 of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic telson
type: Class
equivalent class: Class
  intersection of: telson
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: telson
subclass of: Restriction
  on property: part of
  some values from: embryonic abdomen
definition: Any telson of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000184
in subset: cur

Axiom
annotated source: embryonic telson
annotated property: definition
annotated target: Any telson of the embryo.
database_cross_reference: FBC:Autogenerated

larval tracheal system
type: Class
equivalent class: Class
  intersection of: tracheal system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: tracheal system
subclass of: Restriction
  on property: part of
  some values from: larva
subclass of: Restriction
  on property: develops from
  some values from: presumptive embryonic/larval tracheal system
definition: Tracheal system of the late embryo or larva. The three larval instars retain the same basic pattern of the tracheal system, but with increasing complexity of branch trachea. It is composed of ten tracheal metameres.
has alternative id: FBbt:00005570
has exact synonym: embryonic/larval tracheal system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000185
in subset: cur

Axiom
annotated source: larval tracheal system
annotated property: definition
annotated target: Tracheal system of the late embryo or larva. The three larval instars retain the same basic pattern of the tracheal system, but with increasing complexity of branch trachea. It is composed of ten tracheal metameres.
database_cross_reference: FlyBase:FBrf0034081

embryonic optic lobe primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00007676
definition: Primordium of the late extended germ band and closure embryo that gives rise to the embryonic/larval optic anlage. It corresponds to the middle region that develops from the visual primordium.
database_cross_reference: UBERON:6000186
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000186
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic optic lobe primordium
annotated property: definition
annotated target: Primordium of the late extended germ band and closure embryo that gives rise to the embryonic/larval optic anlage. It corresponds to the middle region that develops from the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

presumptive embryonic/larval digestive system
type: Class
subclass of: presumptive embryonic/larval system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval digestive system.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic digestive system
id: FBbt:00000438
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: presumptive embryonic/larval digestive system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval digestive system.
database_cross_reference: FlyBase:FBrf0007733
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0076136

Axiom
annotated source: presumptive embryonic/larval digestive system
annotated property: hasRelatedSynonym
annotated target: embryonic digestive system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

stomodeum
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval digestive system
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: late stomodeal invagination
definition: The anterior part of the embryonic digestive system deriving from the stomodeal invagination of the ectoderm.
database_cross_reference: UBERON:0000930
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000439
in subset: FB gloss
in subset: cur

Axiom
annotated source: stomodeum
annotated property: definition
annotated target: The anterior part of the embryonic digestive system deriving from the stomodeal invagination of the ectoderm.
database_cross_reference: FBC:GG

hindgut proper primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025992
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: small intestine primordium
  intersection of: Restriction
    on property: develops into
    some values from: large intestine primordium
  intersection of: Restriction
    on property: develops into
    some values from: rectum primordium
  intersection of: Restriction
    on property: develops into
    some values from: embryonic primordium of adult hindgut precursor
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
subclass of: Restriction
  on property: develops from
  some values from: inclusive hindgut primordium
definition: A(n) primordium that develops into some rectum primordium and some large intestine primordium and some small intestine primordium and some embryonic primordium of adult hindgut precursor. It develops from some inclusive hindgut primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: P2 pHiGP
has related synonym: pHiGP2
id: FBbt:00000441
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: hindgut proper primordium
annotated property: definition
annotated target: A(n) primordium that develops into some rectum primordium and some large intestine primordium and some small intestine primordium and some embryonic primordium of adult hindgut precursor. It develops from some inclusive hindgut primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: hindgut proper primordium
annotated property: hasRelatedSynonym
annotated target: P2 pHiGP
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Malpighian tubule primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025992
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: Malpighian tubule main body primordium
  intersection of: Restriction
    on property: develops into
    some values from: Malpighian tubule tip cell primordium
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
subclass of: Restriction
  on property: develops from
  some values from: inclusive hindgut primordium
definition: A(n) primordium that develops into some Malpighian tubule tip cell primordium and some Malpighian tubule main body primordium. It develops from some inclusive hindgut primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: MTP2
has related synonym: P2 MalT
id: FBbt:00000442
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: Malpighian tubule primordium
annotated property: definition
annotated target: A(n) primordium that develops into some Malpighian tubule tip cell primordium and some Malpighian tubule main body primordium. It develops from some inclusive hindgut primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: Malpighian tubule primordium
annotated property: hasRelatedSynonym
annotated target: P2 MalT
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic primordium of adult salivary gland
type: Class
subclass of: embryonic imaginal tissue
subclass of: primordium
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00016006
subclass of: Restriction
  on property: develops into
  some values from: salivary gland imaginal ring
definition: Primordium of the dorsal closure embryo that give rise to the salivary gland imaginal ring which in turn develops into the adult salivary gland.
has exact synonym: adult salivary gland primordium
has OBO namespace: fly_anatomy.ontology
has related synonym: salivary gland placode
id: FBbt:00000443
in subset: cur

Axiom
annotated source: embryonic primordium of adult salivary gland
annotated property: definition
annotated target: Primordium of the dorsal closure embryo that give rise to the salivary gland imaginal ring which in turn develops into the adult salivary gland.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

posterior endoderm anlage
type: Class
subclass of: endoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: posterior endoderm
definition: Region of cells of the early embryo that will invaginate from the posterior dorsal embryo during gastrulation to form the posterior part of the endoderm (Campos-Ortega and Hartenstein, 1997). It is a precursor to the posterior midgut (Campos-Ortega and Hartenstein, 1997).
has exact synonym: posterior midgut anlage
has OBO namespace: fly_anatomy.ontology
has related synonym: Asn/A postEndo
id: FBbt:00000447
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: posterior endoderm anlage
annotated property: definition
annotated target: Region of cells of the early embryo that will invaginate from the posterior dorsal embryo during gastrulation to form the posterior part of the endoderm (Campos-Ortega and Hartenstein, 1997). It is a precursor to the posterior midgut (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: posterior endoderm anlage
annotated property: hasExactSynonym
annotated target: posterior midgut anlage
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: posterior endoderm anlage
annotated property: hasRelatedSynonym
annotated target: Asn/A postEndo
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult midgut progenitor cell
type: Class
subclass of: embryonic/larval midgut cell
subclass of: somatic precursor cell
subclass of: Restriction
  on property: develops from
  some values from: midgut primordium
subclass of: Restriction
  on property: expresses
  some values from: FBgn0001981
definition: A cell that is a progenitor of the adult midgut and occupies a basal position in the midgut epithelium. It divides during larval stages to form clusters called midgut imaginal islands. Its first division is asymmetric and produces a peripheral cell, subsequent divisions generate more adult midgut progenitor cells (Mathur et al., 2010).
has exact synonym: AMP
has exact synonym: adult midgut precursor cell
has exact synonym: midgut histoblast
has exact synonym: spindle cell
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic precursor cell of adult midgut
id: FBbt:00000449
in subset: cur
comment: These cells can be identified by their expression of escargot (Jiang and Edgar, 2009).

Axiom
annotated source: adult midgut progenitor cell
annotated property: definition
annotated target: A cell that is a progenitor of the adult midgut and occupies a basal position in the midgut epithelium. It divides during larval stages to form clusters called midgut imaginal islands. Its first division is asymmetric and produces a peripheral cell, subsequent divisions generate more adult midgut progenitor cells (Mathur et al., 2010).
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0206542
database_cross_reference: FlyBase:FBrf0209706

Axiom
annotated source: adult midgut progenitor cell
annotated property: hasExactSynonym
annotated target: AMP
database_cross_reference: FlyBase:FBrf0209706

Axiom
annotated source: adult midgut progenitor cell
annotated property: hasExactSynonym
annotated target: midgut histoblast
database_cross_reference: FlyBase:FBrf0064803

Axiom
annotated source: adult midgut progenitor cell
annotated property: hasExactSynonym
annotated target: spindle cell
database_cross_reference: FlyBase:FBrf0064792

embryonic inner optic lobe primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: embryonic optic lobe primordium
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: larval inner optic anlage
definition: Primordium of the late extended germ band and closure embryo that gives rise to the larval inner optic anlage. It develops from the anterior lip of the visual primordium.
has exact synonym: P1 IOA
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000461
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic inner optic lobe primordium
annotated property: definition
annotated target: Primordium of the late extended germ band and closure embryo that gives rise to the larval inner optic anlage. It develops from the anterior lip of the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: embryonic inner optic lobe primordium
annotated property: hasExactSynonym
annotated target: P1 IOA
database_cross_reference: https://orcid.org/0000-0002-7073-9172

larval muscle system
type: Class
equivalent class: Class
  intersection of: muscle system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: muscle system
subclass of: Restriction
  on property: part of
  some values from: larva
subclass of: Restriction
  on property: develops from
  some values from: presumptive embryonic/larval muscle system
definition: Muscle system of the larva.
has alternative id: FBbt:00005648
has exact synonym: embryonic/larval muscle system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000462
in subset: cur

Axiom
annotated source: larval muscle system
annotated property: definition
annotated target: Muscle system of the larva.
database_cross_reference: FlyBase:FBrf0031016
database_cross_reference: FlyBase:FBrf0041814
database_cross_reference: FlyBase:FBrf0044229
database_cross_reference: FlyBase:FBrf0064793

larval somatic muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058297
subclass of: somatic muscle cell
subclass of: FBbt_00058231
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058297
subclass of: Restriction
  on property: develops from
  some values from: embryonic somatic muscle cell
definition: Any muscle cell (FBbt:00005074) that is part of some larval somatic muscle (FBbt:00058297).
has alternative id: FBbt:00005650
has exact synonym: embryonic/larval skeletal muscle cell
has exact synonym: embryonic/larval somatic muscle cell
has exact synonym: larval skeletal muscle cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000464
in subset: cur

Axiom
annotated source: larval somatic muscle cell
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some larval somatic muscle (FBbt:00058297).
database_cross_reference: FBC:Autogenerated

larval apodeme
type: Class
equivalent class: Class
  intersection of: apodeme
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: apodeme
subclass of: Restriction
  on property: part of
  some values from: larval integumentary system
definition: Apodeme that is part of the late embryo/larva. Apodemes are not a continuous structure, but are split into two halves. In the embryo, this break is visible laterally. In the larva, the dorsal and ventral halves in the thoracic and abdominal segments are staggered, with the dorsal part being posterior to the ventral one.
has exact synonym: embryonic/larval apodeme
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001005
in subset: cur

Axiom
annotated source: larval apodeme
annotated property: definition
annotated target: Apodeme that is part of the late embryo/larva. Apodemes are not a continuous structure, but are split into two halves. In the embryo, this break is visible laterally. In the larva, the dorsal and ventral halves in the thoracic and abdominal segments are staggered, with the dorsal part being posterior to the ventral one.
database_cross_reference: FBC:SPR
database_cross_reference: FlyBase:FBrf0089570

larval abdominal apodeme
type: Class
equivalent class: Class
  intersection of: FBbt_00007585
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval apodeme
subclass of: FBbt_00007585
definition: Any abdominal apodeme of the larva.
has exact synonym: embryonic/larval abdominal apodeme
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001006
in subset: cur

Axiom
annotated source: larval abdominal apodeme
annotated property: definition
annotated target: Any abdominal apodeme of the larva.
database_cross_reference: FBC:Autogenerated

larval visceral muscle cell
type: Class
equivalent class: Class
  intersection of: visceral muscle cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: visceral muscle cell
subclass of: FBbt_00058231
definition: Muscle cell of a muscle of the embryonic/larval intestinal tract. Circular and longitudinal fibers surround the entire intestinal tract, with the exception of the recurrent layer of the proventriculus. The circular fibers derive from a bilaterally symmetrical band of mesodermal cells extending continuously throughout most of the germ band. The longitudinal fibers derive from clusters of mesodermal cells which appear during stage 12 at the posterior end of the embryo and migrate anteriorly.
has alternative id: FBbt:00005654
has exact synonym: embryonic/larval visceral muscle cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001035
in subset: cur

Axiom
annotated source: larval visceral muscle cell
annotated property: definition
annotated target: Muscle cell of a muscle of the embryonic/larval intestinal tract. Circular and longitudinal fibers surround the entire intestinal tract, with the exception of the recurrent layer of the proventriculus. The circular fibers derive from a bilaterally symmetrical band of mesodermal cells extending continuously throughout most of the germ band. The longitudinal fibers derive from clusters of mesodermal cells which appear during stage 12 at the posterior end of the embryo and migrate anteriorly.
database_cross_reference: FlyBase:FBrf0064793
database_cross_reference: FlyBase:FBrf0089570

embryonic/larval gonadal sheath muscle cell
type: Class
subclass of: larval visceral muscle cell
subclass of: somatic trunk mesoderm derivative
subclass of: FBbt_00026002
subclass of: Restriction
  on property: part of
  some values from: gonadal sheath
subclass of: Restriction
  on property: develops from
  some values from: gonadal sheath proper primordium
definition: Muscle cell of the gonadal sheath muscle of the embryo or larva.
has alternative id: FBbt:00005658
has exact synonym: larval gonadal sheath muscle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001054
in subset: cur

Axiom
annotated source: embryonic/larval gonadal sheath muscle cell
annotated property: definition
annotated target: Muscle cell of the gonadal sheath muscle of the embryo or larva.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

presumptive embryonic/larval nervous system
type: Class
subclass of: presumptive embryonic/larval system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval nervous system.
database_cross_reference: UBERON:6001055
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic nervous system
id: FBbt:00001055
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: presumptive embryonic/larval nervous system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval nervous system.
database_cross_reference: FlyBase:FBrf0031012

Axiom
annotated source: presumptive embryonic/larval nervous system
annotated property: hasRelatedSynonym
annotated target: embryonic nervous system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

presumptive embryonic/larval central nervous system
type: Class
subclass of: presumptive embryonic/larval system
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval nervous system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval central nervous system.
database_cross_reference: UBERON:6001056
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic central nervous system
id: FBbt:00001056
in subset: cur

Axiom
annotated source: presumptive embryonic/larval central nervous system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval central nervous system.
database_cross_reference: FlyBase:FBrf0031012

Axiom
annotated source: presumptive embryonic/larval central nervous system
annotated property: hasRelatedSynonym
annotated target: embryonic central nervous system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

neurogenic region
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: ectoderm
definition: Region that gives rise to the neuroblasts of the central nervous system (Bossing et al., 1996). An anterior region (procephalic neurogenic region) gives rise to the brain and a posterior, ventral region (ventral neuroectoderm) gives rise to the ventral nerve cord and gnathal ganglia (Bossing et al., 1996).
database_cross_reference: UBERON:0002346
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001057
in subset: cur

Axiom
annotated source: neurogenic region
annotated property: definition
annotated target: Region that gives rise to the neuroblasts of the central nervous system (Bossing et al., 1996). An anterior region (procephalic neurogenic region) gives rise to the brain and a posterior, ventral region (ventral neuroectoderm) gives rise to the ventral nerve cord and gnathal ganglia (Bossing et al., 1996).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0090460
database_cross_reference: FlyBase:FBrf0098344

procephalic neurogenic region
type: Class
subclass of: neurogenic region
subclass of: Restriction
  on property: part of
  some values from: anterior ectoderm
subclass of: Restriction
  on property: part of
  some values from: embryonic head
definition: Tissue which becomes morphologically distinct shortly after cephalic furrow formation as two strips of about 80 enlarged cells which extend dorso-ventrally on either side of the developing head. It gives rise to neuroblasts of the brain.
has exact synonym: pregnathal neuroectoderm
has exact synonym: procephalic neuroectoderm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001058
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: procephalic neurogenic region
annotated property: definition
annotated target: Tissue which becomes morphologically distinct shortly after cephalic furrow formation as two strips of about 80 enlarged cells which extend dorso-ventrally on either side of the developing head. It gives rise to neuroblasts of the brain.
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0090460

Axiom
annotated source: procephalic neurogenic region
annotated property: hasExactSynonym
annotated target: pregnathal neuroectoderm
database_cross_reference: FlyBase:FBrf0161020

Axiom
annotated source: procephalic neurogenic region
annotated property: hasExactSynonym
annotated target: procephalic neuroectoderm
database_cross_reference: FlyBase:FBrf0161020

visual primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025991
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: embryonic optic lobe primordium
  intersection of: Restriction
    on property: develops into
    some values from: early embryonic primordium of adult eye
  intersection of: Restriction
    on property: develops into
    some values from: Bolwig organ primordium
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
subclass of: Restriction
  on property: develops from
  some values from: visual anlage
definition: Primordium that develops from the posterior procephalic region of the embryo and gives rise to visual structures of the larva and adult (Green et al., 1993; Chang et al., 2001). An optic placode forms from cells of the visual primordium when they become columnar in shape towards the end of stage 11 (Green et al., 1993; Chang et al., 2001). This placode invaginates during stages 12-13, forming a deep pouch of approximately 85 cells (Green et al., 1993). Its ventral lip segregates from the rest of the primordium and develops into the Bolwig organ (Green et al., 1993). The remainder of the placode, which will form the optic lobe, detaches from the surface of the embryo and attaches to the lateral brain, maintaining a tubular appearance until larval hatching (Green et al., 1993). Its anterior and posterior domains will become the larval inner and outer optic anlage, respectively (Chang et al., 2001). The cells that will become the eye disc are anterior and dorsal to the optic lobe placode cells (Chang et al., 2001). They move into the interior of the embryo during head involution, when they are pushed under the dorsal ridge (Huang et al., 2017).
database_cross_reference: UBERON:6001059
has narrow synonym: optic lobe placode
has narrow synonym: optic lobe primordium
has OBO namespace: fly_anatomy.ontology
has related synonym: P2 VisSys
id: FBbt:00001059
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: visual primordium
annotated property: definition
annotated target: Primordium that develops from the posterior procephalic region of the embryo and gives rise to visual structures of the larva and adult (Green et al., 1993; Chang et al., 2001). An optic placode forms from cells of the visual primordium when they become columnar in shape towards the end of stage 11 (Green et al., 1993; Chang et al., 2001). This placode invaginates during stages 12-13, forming a deep pouch of approximately 85 cells (Green et al., 1993). Its ventral lip segregates from the rest of the primordium and develops into the Bolwig organ (Green et al., 1993). The remainder of the placode, which will form the optic lobe, detaches from the surface of the embryo and attaches to the lateral brain, maintaining a tubular appearance until larval hatching (Green et al., 1993). Its anterior and posterior domains will become the larval inner and outer optic anlage, respectively (Chang et al., 2001). The cells that will become the eye disc are anterior and dorsal to the optic lobe placode cells (Chang et al., 2001). They move into the interior of the embryo during head involution, when they are pushed under the dorsal ridge (Huang et al., 2017).
database_cross_reference: FlyBase:FBrf0064481
database_cross_reference: FlyBase:FBrf0141490
database_cross_reference: FlyBase:FBrf0235170
database_cross_reference: FlyBase:FBrf0243080

Axiom
annotated source: visual primordium
annotated property: hasNarrowSynonym
annotated target: optic lobe placode
database_cross_reference: FlyBase:FBrf0141490

Axiom
annotated source: visual primordium
annotated property: hasRelatedSynonym
annotated target: P2 VisSys
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic brain
type: Class
subclass of: supraesophageal ganglion
subclass of: brain
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval central nervous system
subclass of: Restriction
  on property: develops from
  some values from: procephalic neurogenic region
definition: Brain of the embryo, consisting of the protocerebrum, deutocerebrum and tritocerebrum (Urbach and Technau, 2003; Crews, 2019). It develops from the procephalic neurogenic region (Urbach and Technau, 2003).
database_cross_reference: UBERON:6001060
database_cross_reference: VFB:FBbt_00001060
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001060
in subset: cur

Axiom
annotated source: embryonic brain
annotated property: definition
annotated target: Brain of the embryo, consisting of the protocerebrum, deutocerebrum and tritocerebrum (Urbach and Technau, 2003; Crews, 2019). It develops from the procephalic neurogenic region (Urbach and Technau, 2003).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0244240

ventral neurectoderm
type: Class
subclass of: neurogenic region
subclass of: epithelium
subclass of: Restriction
  on property: part of
  some values from: ventral ectoderm
definition: The ventrally/medially located ectodermal region of the trunk from which neuroblasts delaminate to form the ventral nerve cord and gnathal ganglia. This region becomes distinct during stage 8 when its cells become enlarged compared to those in the adjacent dorsal ectoderm.
has alternative id: FBbt:00000113
has exact synonym: P2 VenEc
has exact synonym: VenEc
has exact synonym: vNR
has exact synonym: ventral neurogenic region
has OBO namespace: fly_anatomy.ontology
has related synonym: neurectoderm
has related synonym: neuroectoderm
id: FBbt:00001061
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral neurectoderm
annotated property: definition
annotated target: The ventrally/medially located ectodermal region of the trunk from which neuroblasts delaminate to form the ventral nerve cord and gnathal ganglia. This region becomes distinct during stage 8 when its cells become enlarged compared to those in the adjacent dorsal ectoderm.
database_cross_reference: FlyBase:FBrf0076117
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: ventral neurectoderm
annotated property: hasExactSynonym
annotated target: vNR
database_cross_reference: FlyBase:FBrf0090460

Axiom
annotated source: ventral neurectoderm
annotated property: hasExactSynonym
annotated target: ventral neurogenic region
database_cross_reference: FlyBase:FBrf0090460

embryonic supraesophageal neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: supraesophageal ganglion
subclass of: FBbt_00052717
subclass of: Restriction
  on property: part of
  some values from: embryonic brain
definition: Neuromere of the embryonic supraesophageal ganglion, anterior to the subesophageal ganglion.
database_cross_reference: VFB:FBbt_00001062
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001062
in subset: cur

Axiom
annotated source: embryonic supraesophageal neuromere
annotated property: definition
annotated target: Neuromere of the embryonic supraesophageal ganglion, anterior to the subesophageal ganglion.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

embryonic deutocerebrum
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: embryonic supraesophageal neuromere
subclass of: deutocerebrum
subclass of: Restriction
  on property: part of
  some values from: embryonic antennal segment
subclass of: Restriction
  on property: part of
  some values from: embryonic central brain
definition: Deutocerebrum of the embryo. It is the middle one of the three supraesophageal neuromeres, posterior to the protocerebrum and anterior to the tritocerebrum. It is part of the antennal segment.
has alternative id: FBbt:00001958
database_cross_reference: VFB:FBbt_00001067
has exact synonym: embryonic deuterocerebral neuromere
has exact synonym: embryonic deuterocerebrum
has exact synonym: embryonic deutocerebral neuromere
has exact synonym: neuromere b2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001067
in subset: cur

Axiom
annotated source: embryonic deutocerebrum
annotated property: definition
annotated target: Deutocerebrum of the embryo. It is the middle one of the three supraesophageal neuromeres, posterior to the protocerebrum and anterior to the tritocerebrum. It is part of the antennal segment.
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0161020

Axiom
annotated source: embryonic deutocerebrum
annotated property: hasExactSynonym
annotated target: neuromere b2
database_cross_reference: FlyBase:FBrf0084032

embryonic tritocerebrum
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: embryonic supraesophageal neuromere
subclass of: tritocerebrum
subclass of: Restriction
  on property: part of
  some values from: embryonic intercalary segment
subclass of: Restriction
  on property: part of
  some values from: embryonic central brain
definition: Tritocerebrum of the embryonic brain. It is the most posterior of the three supraesophageal neuromeres. It is part of the intercalary segment.
has alternative id: FBbt:00001963
database_cross_reference: VFB:FBbt_00001068
has exact synonym: embryonic tritocerebral neuromere
has exact synonym: neuromere b3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001068
in subset: cur

Axiom
annotated source: embryonic tritocerebrum
annotated property: definition
annotated target: Tritocerebrum of the embryonic brain. It is the most posterior of the three supraesophageal neuromeres. It is part of the intercalary segment.
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0161020

Axiom
annotated source: embryonic tritocerebrum
annotated property: hasExactSynonym
annotated target: neuromere b3
database_cross_reference: FlyBase:FBrf0084032

embryonic ventral nerve cord
type: Class
subclass of: ventral nerve cord
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval central nervous system
definition: The developing ventral nerve cord of the embryo.
database_cross_reference: VFB:FBbt_00001082
has exact synonym: embryonic ventral nervous system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001082
in subset: cur

Axiom
annotated source: embryonic ventral nerve cord
annotated property: definition
annotated target: The developing ventral nerve cord of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic gnathal neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: gnathal segment
subclass of: FBbt_00052717
subclass of: FBbt_00111266
subclass of: Restriction
  on property: part of
  some values from: embryonic gnathal segment
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval central nervous system
definition: Neuromere of the embryonic subesophageal ganglion, posterior to the supraesophageal ganglion. There are three of these neuromeres: mandibular, maxillary and labial.
database_cross_reference: VFB:FBbt_00001083
has exact synonym: embryonic subesophageal neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001083
in subset: cur

Axiom
annotated source: embryonic gnathal neuromere
annotated property: definition
annotated target: Neuromere of the embryonic subesophageal ganglion, posterior to the supraesophageal ganglion. There are three of these neuromeres: mandibular, maxillary and labial.
database_cross_reference: FlyBase:FBrf0089570

embryonic labial neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: labial segment
subclass of: embryonic gnathal neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic labial segment
definition: The most posterior of the embryonic subesophageal neuromeres. It is part of the labial segment, and it is located posterior to the maxillary neuromere.
database_cross_reference: VFB:FBbt_00001084
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001084
in subset: cur

Axiom
annotated source: embryonic labial neuromere
annotated property: definition
annotated target: The most posterior of the embryonic subesophageal neuromeres. It is part of the labial segment, and it is located posterior to the maxillary neuromere.
database_cross_reference: FlyBase:FBrf0089570

embryonic maxillary neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: maxillary segment
subclass of: embryonic gnathal neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic maxillary segment
definition: The middle of the embryonic subesophageal neuromeres. It is part of the maxillary segment, and it is located anterior to the labial neuromere and posterior to the mandibular one.
database_cross_reference: VFB:FBbt_00001085
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001085
in subset: cur

Axiom
annotated source: embryonic maxillary neuromere
annotated property: definition
annotated target: The middle of the embryonic subesophageal neuromeres. It is part of the maxillary segment, and it is located anterior to the labial neuromere and posterior to the mandibular one.
database_cross_reference: FlyBase:FBrf0089570

embryonic mandibular neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: mandibular segment
subclass of: embryonic gnathal neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic mandibular segment
definition: The most anterior of the embryonic subesophageal neuromeres. It is part of the mandibular segment, and it is located anterior to the maxillary neuromere, and posterior to intercalary segment and its neuromere, the tritocerebrum.
database_cross_reference: VFB:FBbt_00001086
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001086
in subset: cur

Axiom
annotated source: embryonic mandibular neuromere
annotated property: definition
annotated target: The most anterior of the embryonic subesophageal neuromeres. It is part of the mandibular segment, and it is located anterior to the maxillary neuromere, and posterior to intercalary segment and its neuromere, the tritocerebrum.
database_cross_reference: FlyBase:FBrf0089570

embryonic VNC neuromere
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: embryonic ventral nerve cord
subclass of: FBbt_00052717
subclass of: Restriction
  on property: part of
  some values from: embryonic ventral nerve cord
definition: Neuromere of the embryonic ventral nerve cord.
database_cross_reference: VFB:FBbt_00001087
has exact synonym: embryonic ventral neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001087
in subset: cur

Axiom
annotated source: embryonic VNC neuromere
annotated property: definition
annotated target: Neuromere of the embryonic ventral nerve cord.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic thoracic neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: thoracic segment
subclass of: embryonic VNC neuromere
subclass of: FBbt_00111026
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic segment
definition: Any embryonic neuromere (FBbt:00052717) that is part of some thoracic segment (FBbt:00000016).
database_cross_reference: VFB:FBbt_00001088
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001088
in subset: cur

Axiom
annotated source: embryonic thoracic neuromere
annotated property: definition
annotated target: Any embryonic neuromere (FBbt:00052717) that is part of some thoracic segment (FBbt:00000016).
database_cross_reference: FBC:Autogenerated

embryonic prothoracic neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: embryonic thoracic neuromere
subclass of: prothoracic neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic prothoracic segment
definition: Any embryonic neuromere (FBbt:00052717) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: VFB:FBbt_00001089
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001089
in subset: cur

Axiom
annotated source: embryonic prothoracic neuromere
annotated property: definition
annotated target: Any embryonic neuromere (FBbt:00052717) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

embryonic mesothoracic neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: embryonic thoracic neuromere
subclass of: mesothoracic neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic mesothoracic segment
definition: Any embryonic neuromere (FBbt:00052717) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: VFB:FBbt_00001090
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001090
in subset: cur

Axiom
annotated source: embryonic mesothoracic neuromere
annotated property: definition
annotated target: Any embryonic neuromere (FBbt:00052717) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: FBC:Autogenerated

embryonic metathoracic neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: embryonic thoracic neuromere
subclass of: metathoracic neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic metathoracic segment
definition: Any embryonic neuromere (FBbt:00052717) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: VFB:FBbt_00001091
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001091
in subset: cur

Axiom
annotated source: embryonic metathoracic neuromere
annotated property: definition
annotated target: Any embryonic neuromere (FBbt:00052717) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: FBC:Autogenerated

embryonic abdominal neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment
subclass of: embryonic VNC neuromere
subclass of: abdominal neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal segment
definition: Any embryonic neuromere (FBbt:00052717) that is part of some abdominal segment (FBbt:00000021).
database_cross_reference: VFB:FBbt_00001092
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001092
in subset: cur

Axiom
annotated source: embryonic abdominal neuromere
annotated property: definition
annotated target: Any embryonic neuromere (FBbt:00052717) that is part of some abdominal segment (FBbt:00000021).
database_cross_reference: FBC:Autogenerated

embryonic abdominal 6 neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 6
subclass of: embryonic abdominal neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal segment 6
definition: Any embryonic neuromere (FBbt:00052717) that is part of some abdominal segment 6 (FBbt:00000027).
database_cross_reference: VFB:FBbt_00001098
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001098
in subset: cur

Axiom
annotated source: embryonic abdominal 6 neuromere
annotated property: definition
annotated target: Any embryonic neuromere (FBbt:00052717) that is part of some abdominal segment 6 (FBbt:00000027).
database_cross_reference: FBC:Autogenerated

embryonic abdominal 8 neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 8
subclass of: embryonic abdominal neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal segment 8
definition: Any embryonic neuromere (FBbt:00052717) that is part of some abdominal segment 8 (FBbt:00000029).
database_cross_reference: VFB:FBbt_00001100
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001100
in subset: cur

Axiom
annotated source: embryonic abdominal 8 neuromere
annotated property: definition
annotated target: Any embryonic neuromere (FBbt:00052717) that is part of some abdominal segment 8 (FBbt:00000029).
database_cross_reference: FBC:Autogenerated

embryonic abdominal 9 neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052717
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 9
subclass of: embryonic abdominal neuromere
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal segment 9
definition: Any embryonic neuromere (FBbt:00052717) that is part of some abdominal segment 9 (FBbt:00000030).
database_cross_reference: VFB:FBbt_00001101
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001101
in subset: cur

Axiom
annotated source: embryonic abdominal 9 neuromere
annotated property: definition
annotated target: Any embryonic neuromere (FBbt:00052717) that is part of some abdominal segment 9 (FBbt:00000030).
database_cross_reference: FBC:Autogenerated

larval ventral nerve cord
type: Class
subclass of: ventral nerve cord
subclass of: ganglion
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: larval central nervous system
subclass of: Restriction
  on property: develops from
  some values from: ventral nerve cord primordium
definition: Region of the larval central nervous system posterior to the gnathal neuromeres (Clark et al., 2018; Eschbach and Zlatic, 2020; Miroschnikow et al., 2020). It consists of three thoracic neuromeres, eight abdominal neuromeres and a terminal plexus (Clark et al., 2018).
has alternative id: FBbt:00001971
database_cross_reference: VFB:FBbt_00001102
has exact synonym: larval ventral ganglion
has exact synonym: vnc
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral cord
id: FBbt:00001102
in subset: cur
comment: There is some inconsistency in the literature as to whether the larval gnathal ganglion is a part of the ventral nerve cord, many recent papers consider it to be a distinct region, so it is not included here.

Axiom
annotated source: larval ventral nerve cord
annotated property: definition
annotated target: Region of the larval central nervous system posterior to the gnathal neuromeres (Clark et al., 2018; Eschbach and Zlatic, 2020; Miroschnikow et al., 2020). It consists of three thoracic neuromeres, eight abdominal neuromeres and a terminal plexus (Clark et al., 2018).
database_cross_reference: FlyBase:FBrf0238752
database_cross_reference: FlyBase:FBrf0246261
database_cross_reference: FlyBase:FBrf0247585

larval longitudinal connective
type: Class
subclass of: connective
subclass of: FBbt_00047551
subclass of: Restriction
  on property: innervates
  some values from: larval ventral nerve cord
definition: Larval connective that extends in an anterior-posterior direction along the larval ventral nerve cord. These tracts continue forward into the subesophageal zone and bend laterally following the outline of the esophageal foramen (Hartenstein et al., 2018). They then converge, with their fibers forming a complex system of anastomoses before continuing into tracts of the supraesophageal ganglion (Hartenstein et al., 2017).
database_cross_reference: VFB:FBbt_00001103
has exact synonym: embryonic/larval longitudinal connective
has exact synonym: longitudinal tract of ventral nerve cord
has exact synonym: ventral nerve connective
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001103
in subset: cur

Axiom
annotated source: larval longitudinal connective
annotated property: definition
annotated target: Larval connective that extends in an anterior-posterior direction along the larval ventral nerve cord. These tracts continue forward into the subesophageal zone and bend laterally following the outline of the esophageal foramen (Hartenstein et al., 2018). They then converge, with their fibers forming a complex system of anastomoses before continuing into tracts of the supraesophageal ganglion (Hartenstein et al., 2017).
database_cross_reference: FlyBase:FBrf0160715
database_cross_reference: FlyBase:FBrf0215457
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: larval longitudinal connective
annotated property: hasExactSynonym
annotated target: longitudinal tract of ventral nerve cord
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: larval longitudinal connective
annotated property: hasExactSynonym
annotated target: ventral nerve connective
database_cross_reference: FlyBase:FBrf0215457

larval ventral nerve cord commissure
type: Class
equivalent class: Class
  intersection of: FBbt_00049998
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: FBbt_00047551
subclass of: FBbt_00049998
subclass of: Restriction
  on property: part of
  some values from: larval ventral nerve cord
definition: Commissure of the ventral nerve cord at late embryonic or larval stages. There are two main commissures per segment, anterior and posterior, but the posterior commissure is not present in A9 (Landgraf et al., 2003; Birkholz et al., 2015). In some segments, at some stages these can be further divided into multiple components along the dorsal-ventral axis (Truman et al., 2004; Birkholz et al., 2015; Hartenstein et al., 2018).
database_cross_reference: VFB:FBbt_00001104
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001104
in subset: cur

Axiom
annotated source: larval ventral nerve cord commissure
annotated property: definition
annotated target: Commissure of the ventral nerve cord at late embryonic or larval stages. There are two main commissures per segment, anterior and posterior, but the posterior commissure is not present in A9 (Landgraf et al., 2003; Birkholz et al., 2015). In some segments, at some stages these can be further divided into multiple components along the dorsal-ventral axis (Truman et al., 2004; Birkholz et al., 2015; Hartenstein et al., 2018).
database_cross_reference: FlyBase:FBrf0160715
database_cross_reference: FlyBase:FBrf0180161
database_cross_reference: FlyBase:FBrf0228122
database_cross_reference: FlyBase:FBrf0237252

presumptive embryonic/larval peripheral nervous system
type: Class
subclass of: presumptive embryonic/larval system
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval nervous system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval peripheral nervous system.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic peripheral nervous system
id: FBbt:00001134
in subset: cur

Axiom
annotated source: presumptive embryonic/larval peripheral nervous system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval peripheral nervous system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: presumptive embryonic/larval peripheral nervous system
annotated property: hasRelatedSynonym
annotated target: embryonic peripheral nervous system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

proneural cluster
type: Class
subclass of: anlage
definition: An equivalence group of the neurectoderm where all cells can, although only one will, become a neural progenitor cell.
database_cross_reference: UBERON:6001135
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001135
in subset: cur

Axiom
annotated source: proneural cluster
annotated property: definition
annotated target: An equivalence group of the neurectoderm where all cells can, although only one will, become a neural progenitor cell.
database_cross_reference: FlyBase:FBrf0074477
database_cross_reference: FlyBase:FBrf0089570

sensory mother cell
type: Class
subclass of: FBbt_00052556
subclass of: Restriction
  on property: part of
  some values from: proneural cluster
definition: Precursor cell that can give rise to all the neuronal and support cells that form a peripheral sense organ.
has exact synonym: SMC
has exact synonym: SOP
has exact synonym: sensory organ precursor cell
has exact synonym: sensory organ progenitor cell
has OBO namespace: fly_anatomy.ontology
has related synonym: sensillum precursor
has related synonym: sensory organ mother cell
id: FBbt:00001137
in subset: cur

Axiom
annotated source: sensory mother cell
annotated property: definition
annotated target: Precursor cell that can give rise to all the neuronal and support cells that form a peripheral sense organ.
database_cross_reference: FlyBase:FBrf0055951
database_cross_reference: FlyBase:FBrf0083795
database_cross_reference: FlyBase:FBrf0132424

Axiom
annotated source: sensory mother cell
annotated property: hasExactSynonym
annotated target: SMC
database_cross_reference: FlyBase:FBrf0055951

Axiom
annotated source: sensory mother cell
annotated property: hasExactSynonym
annotated target: SOP
database_cross_reference: FlyBase:FBrf0132424

Axiom
annotated source: sensory mother cell
annotated property: hasExactSynonym
annotated target: sensory organ precursor cell
database_cross_reference: FlyBase:FBrf0132424

Axiom
annotated source: sensory mother cell
annotated property: hasExactSynonym
annotated target: sensory organ progenitor cell
database_cross_reference: FlyBase:FBrf0132424

peripheral nervous system precursor cluster
type: Class
subclass of: FBbt_00007276
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval peripheral nervous system
subclass of: Restriction
  on property: develops from
  some values from: sensory nervous system primordium
definition: A cluster of embryonic precursors that will give rise to sensory organs in the late embryo and larva (Ghysen et al., 1986; Bodmer and Jan, 1987).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001139
in subset: cur

Axiom
annotated source: peripheral nervous system precursor cluster
annotated property: definition
annotated target: A cluster of embryonic precursors that will give rise to sensory organs in the late embryo and larva (Ghysen et al., 1986; Bodmer and Jan, 1987).
database_cross_reference: FlyBase:FBrf0045361
database_cross_reference: FlyBase:FBrf0047289

embryonic thoracic dorsal sensory organ precursor cluster
type: Class
equivalent class: Class
  intersection of: FBbt_00059182
  intersection of: Restriction
    on property: part of
    some values from: thoracic segment
subclass of: FBbt_00059182
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic segment
subclass of: Restriction
  on property: part of
  some values from: embryonic nervous system of thorax
definition: Any embryonic dorsal sensory organ precursor cluster (FBbt:00059182) that is part of some thoracic segment (FBbt:00000016).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001140
in subset: cur

Axiom
annotated source: embryonic thoracic dorsal sensory organ precursor cluster
annotated property: definition
annotated target: Any embryonic dorsal sensory organ precursor cluster (FBbt:00059182) that is part of some thoracic segment (FBbt:00000016).
database_cross_reference: FlyBase:FBrf0047289

dorsal thoracic dendritic arborizing neuron precursor cell
type: Class
equivalent class: Class
  intersection of: FBbt_00058153
  intersection of: Restriction
    on property: part of
    some values from: embryonic thoracic dorsal sensory organ precursor cluster
subclass of: developing embryonic structure
subclass of: FBbt_00058153
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic dorsal sensory organ precursor cluster
definition: Any dendritic arborizing neuron precursor cell (FBbt:00058153) that is part of some embryonic thoracic dorsal sensory organ precursor cluster (FBbt:00001140).
has broad synonym: dorsal thoracic da cell
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal thoracic dendritic arborizing sensory organ precursor cell
id: FBbt:00001141
in subset: cur

Axiom
annotated source: dorsal thoracic dendritic arborizing neuron precursor cell
annotated property: definition
annotated target: Any dendritic arborizing neuron precursor cell (FBbt:00058153) that is part of some embryonic thoracic dorsal sensory organ precursor cluster (FBbt:00001140).
database_cross_reference: FlyBase:FBrf0047289

Axiom
annotated source: dorsal thoracic dendritic arborizing neuron precursor cell
annotated property: hasBroadSynonym
annotated target: dorsal thoracic da cell
database_cross_reference: FlyBase:FBrf0047289

dorsal thoracic external sensory organ precursor cell
type: Class
equivalent class: Class
  intersection of: external sensory organ precursor cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic thoracic dorsal sensory organ precursor cluster
subclass of: developing embryonic structure
subclass of: external sensory organ precursor cell
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic dorsal sensory organ precursor cluster
definition: Any external sensory organ precursor cell (FBbt:00005164) that is part of some embryonic thoracic dorsal sensory organ precursor cluster (FBbt:00001140).
has broad synonym: dorsal thoracic es cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001147
in subset: cur

Axiom
annotated source: dorsal thoracic external sensory organ precursor cell
annotated property: definition
annotated target: Any external sensory organ precursor cell (FBbt:00005164) that is part of some embryonic thoracic dorsal sensory organ precursor cluster (FBbt:00001140).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: dorsal thoracic external sensory organ precursor cell
annotated property: hasBroadSynonym
annotated target: dorsal thoracic es cell
database_cross_reference: FlyBase:FBrf0047289

dorsal thoracic chordotonal organ precursor cell
type: Class
equivalent class: Class
  intersection of: chordotonal organ precursor cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic thoracic dorsal sensory organ precursor cluster
subclass of: developing embryonic structure
subclass of: chordotonal organ precursor cell
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic dorsal sensory organ precursor cluster
definition: Any chordotonal organ precursor cell (FBbt:00005216) that is part of some embryonic thoracic dorsal sensory organ precursor cluster (FBbt:00001140).
has broad synonym: dorsal thoracic ch cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001154
in subset: cur

Axiom
annotated source: dorsal thoracic chordotonal organ precursor cell
annotated property: definition
annotated target: Any chordotonal organ precursor cell (FBbt:00005216) that is part of some embryonic thoracic dorsal sensory organ precursor cluster (FBbt:00001140).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: dorsal thoracic chordotonal organ precursor cell
annotated property: hasBroadSynonym
annotated target: dorsal thoracic ch cell
database_cross_reference: FlyBase:FBrf0047289

embryonic thoracic ventral sensory organ precursor cluster group
type: Class
equivalent class: Class
  intersection of: FBbt_00059198
  intersection of: Restriction
    on property: part of
    some values from: thoracic segment
subclass of: FBbt_00059198
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic segment
definition: Any embryonic ventral sensory organ precursor cluster group (FBbt:00059198) that is part of some thoracic segment (FBbt:00000016).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001172
in subset: cur

Axiom
annotated source: embryonic thoracic ventral sensory organ precursor cluster group
annotated property: definition
annotated target: Any embryonic ventral sensory organ precursor cluster group (FBbt:00059198) that is part of some thoracic segment (FBbt:00000016).
database_cross_reference: FlyBase:FBrf0047289

ventral group thoracic dendritic arborizing neuron precursor cell
type: Class
equivalent class: Class
  intersection of: FBbt_00058153
  intersection of: Restriction
    on property: part of
    some values from: embryonic thoracic ventral sensory organ precursor cluster group
subclass of: developing embryonic structure
subclass of: FBbt_00058153
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic ventral sensory organ precursor cluster group
definition: Any dendritic arborizing neuron precursor cell (FBbt:00058153) that is part of some embryonic thoracic ventral sensory organ precursor cluster group (FBbt:00001172).
has broad synonym: ventral thoracic da cell
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral thoracic dendritic arborizing sensory organ precursor cell
id: FBbt:00001173
in subset: cur

Axiom
annotated source: ventral group thoracic dendritic arborizing neuron precursor cell
annotated property: definition
annotated target: Any dendritic arborizing neuron precursor cell (FBbt:00058153) that is part of some embryonic thoracic ventral sensory organ precursor cluster group (FBbt:00001172).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: ventral group thoracic dendritic arborizing neuron precursor cell
annotated property: hasBroadSynonym
annotated target: ventral thoracic da cell
database_cross_reference: FlyBase:FBrf0047289

ventral group thoracic external sensory organ precursor cell
type: Class
equivalent class: Class
  intersection of: external sensory organ precursor cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic thoracic ventral sensory organ precursor cluster group
subclass of: developing embryonic structure
subclass of: external sensory organ precursor cell
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic ventral sensory organ precursor cluster group
definition: Any external sensory organ precursor cell (FBbt:00005164) that is part of some embryonic thoracic ventral sensory organ precursor cluster group (FBbt:00001172).
has broad synonym: ventral thoracic es cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001178
in subset: cur

Axiom
annotated source: ventral group thoracic external sensory organ precursor cell
annotated property: definition
annotated target: Any external sensory organ precursor cell (FBbt:00005164) that is part of some embryonic thoracic ventral sensory organ precursor cluster group (FBbt:00001172).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: ventral group thoracic external sensory organ precursor cell
annotated property: hasBroadSynonym
annotated target: ventral thoracic es cell
database_cross_reference: FlyBase:FBrf0047289

ventral group thoracic chordotonal organ precursor cell
type: Class
equivalent class: Class
  intersection of: chordotonal organ precursor cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic thoracic ventral sensory organ precursor cluster group
subclass of: developing embryonic structure
subclass of: chordotonal organ precursor cell
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic ventral sensory organ precursor cluster group
definition: Any chordotonal organ precursor cell (FBbt:00005216) that is part of some embryonic thoracic ventral sensory organ precursor cluster group (FBbt:00001172).
has broad synonym: ventral thoracic ch cell
has broad synonym: ventral thoracic ch1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001189
in subset: cur

Axiom
annotated source: ventral group thoracic chordotonal organ precursor cell
annotated property: definition
annotated target: Any chordotonal organ precursor cell (FBbt:00005216) that is part of some embryonic thoracic ventral sensory organ precursor cluster group (FBbt:00001172).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: ventral group thoracic chordotonal organ precursor cell
annotated property: hasBroadSynonym
annotated target: ventral thoracic ch cell
database_cross_reference: FlyBase:FBrf0047289

embryonic abdominal dorsal sensory organ precursor cluster
type: Class
equivalent class: Class
  intersection of: FBbt_00059182
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment
subclass of: FBbt_00059182
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal segment
subclass of: Restriction
  on property: part of
  some values from: embryonic nervous system of abdomen
definition: Any embryonic dorsal sensory organ precursor cluster (FBbt:00059182) that is part of some abdominal segment (FBbt:00000021).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001190
in subset: cur

Axiom
annotated source: embryonic abdominal dorsal sensory organ precursor cluster
annotated property: definition
annotated target: Any embryonic dorsal sensory organ precursor cluster (FBbt:00059182) that is part of some abdominal segment (FBbt:00000021).
database_cross_reference: FlyBase:FBrf0047289

dorsal abdominal dendritic arborizing neuron precursor cell
type: Class
equivalent class: Class
  intersection of: FBbt_00058153
  intersection of: Restriction
    on property: part of
    some values from: embryonic abdominal dorsal sensory organ precursor cluster
subclass of: developing embryonic structure
subclass of: FBbt_00058153
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal dorsal sensory organ precursor cluster
definition: Any dendritic arborizing neuron precursor cell (FBbt:00058153) that is part of some embryonic abdominal dorsal sensory organ precursor cluster (FBbt:00001190).
has broad synonym: dorsal abdominal da cell
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal abdominal dendritic arborizing sensory organ precursor cell
id: FBbt:00001191
in subset: cur

Axiom
annotated source: dorsal abdominal dendritic arborizing neuron precursor cell
annotated property: definition
annotated target: Any dendritic arborizing neuron precursor cell (FBbt:00058153) that is part of some embryonic abdominal dorsal sensory organ precursor cluster (FBbt:00001190).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: dorsal abdominal dendritic arborizing neuron precursor cell
annotated property: hasBroadSynonym
annotated target: dorsal abdominal da cell
database_cross_reference: FlyBase:FBrf0047289

dorsal abdominal external sensory organ precursor cell
type: Class
equivalent class: Class
  intersection of: external sensory organ precursor cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic abdominal dorsal sensory organ precursor cluster
subclass of: developing embryonic structure
subclass of: external sensory organ precursor cell
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal dorsal sensory organ precursor cluster
definition: Any external sensory organ precursor cell (FBbt:00005164) that is part of some embryonic abdominal dorsal sensory organ precursor cluster (FBbt:00001190).
has broad synonym: dorsal abdominal es cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001197
in subset: cur

Axiom
annotated source: dorsal abdominal external sensory organ precursor cell
annotated property: definition
annotated target: Any external sensory organ precursor cell (FBbt:00005164) that is part of some embryonic abdominal dorsal sensory organ precursor cluster (FBbt:00001190).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: dorsal abdominal external sensory organ precursor cell
annotated property: hasBroadSynonym
annotated target: dorsal abdominal es cell
database_cross_reference: FlyBase:FBrf0047289

dorsal abdominal chordotonal organ precursor cell
type: Class
equivalent class: Class
  intersection of: chordotonal organ precursor cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic abdominal dorsal sensory organ precursor cluster
subclass of: developing embryonic structure
subclass of: chordotonal organ precursor cell
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal dorsal sensory organ precursor cluster
definition: Any chordotonal organ precursor cell (FBbt:00005216) that is part of some embryonic abdominal dorsal sensory organ precursor cluster (FBbt:00001190).
has broad synonym: dorsal abdominal ch cell
has broad synonym: dorsal abdominal ch1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001203
in subset: cur

Axiom
annotated source: dorsal abdominal chordotonal organ precursor cell
annotated property: definition
annotated target: Any chordotonal organ precursor cell (FBbt:00005216) that is part of some embryonic abdominal dorsal sensory organ precursor cluster (FBbt:00001190).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: dorsal abdominal chordotonal organ precursor cell
annotated property: hasBroadSynonym
annotated target: dorsal abdominal ch cell
database_cross_reference: FlyBase:FBrf0047289

embryonic abdominal ventral sensory organ precursor cluster group
type: Class
equivalent class: Class
  intersection of: FBbt_00059198
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment
subclass of: FBbt_00059198
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal segment
definition: Any embryonic ventral sensory organ precursor cluster group (FBbt:00059198) that is part of some abdominal segment (FBbt:00000021).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001220
in subset: cur

Axiom
annotated source: embryonic abdominal ventral sensory organ precursor cluster group
annotated property: definition
annotated target: Any embryonic ventral sensory organ precursor cluster group (FBbt:00059198) that is part of some abdominal segment (FBbt:00000021).
database_cross_reference: FlyBase:FBrf0047289

ventral group abdominal dendritic arborizing neuron precursor cell
type: Class
equivalent class: Class
  intersection of: FBbt_00058153
  intersection of: Restriction
    on property: part of
    some values from: embryonic abdominal ventral sensory organ precursor cluster group
subclass of: developing embryonic structure
subclass of: FBbt_00058153
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal ventral sensory organ precursor cluster group
definition: Any dendritic arborizing neuron precursor cell (FBbt:00058153) that is part of some embryonic abdominal ventral sensory organ precursor cluster group (FBbt:00001220).
has broad synonym: ventral abdominal da cell
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral abdominal dendritic arborizing sensory organ precursor cell
id: FBbt:00001221
in subset: cur

Axiom
annotated source: ventral group abdominal dendritic arborizing neuron precursor cell
annotated property: definition
annotated target: Any dendritic arborizing neuron precursor cell (FBbt:00058153) that is part of some embryonic abdominal ventral sensory organ precursor cluster group (FBbt:00001220).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: ventral group abdominal dendritic arborizing neuron precursor cell
annotated property: hasBroadSynonym
annotated target: ventral abdominal da cell
database_cross_reference: FlyBase:FBrf0047289

ventral group abdominal external sensory organ precursor cell
type: Class
equivalent class: Class
  intersection of: external sensory organ precursor cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic abdominal ventral sensory organ precursor cluster group
subclass of: developing embryonic structure
subclass of: external sensory organ precursor cell
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal ventral sensory organ precursor cluster group
definition: Any external sensory organ precursor cell (FBbt:00005164) that is part of some embryonic abdominal ventral sensory organ precursor cluster group (FBbt:00001220).
has broad synonym: ventral abdominal es cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001229
in subset: cur

Axiom
annotated source: ventral group abdominal external sensory organ precursor cell
annotated property: definition
annotated target: Any external sensory organ precursor cell (FBbt:00005164) that is part of some embryonic abdominal ventral sensory organ precursor cluster group (FBbt:00001220).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: ventral group abdominal external sensory organ precursor cell
annotated property: hasBroadSynonym
annotated target: ventral abdominal es cell
database_cross_reference: FlyBase:FBrf0047289

ventral group abdominal chordotonal organ precursor cell
type: Class
equivalent class: Class
  intersection of: chordotonal organ precursor cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic abdominal ventral sensory organ precursor cluster group
subclass of: developing embryonic structure
subclass of: chordotonal organ precursor cell
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal ventral sensory organ precursor cluster group
definition: Any chordotonal organ precursor cell (FBbt:00005216) that is part of some embryonic abdominal ventral sensory organ precursor cluster group (FBbt:00001220).
has broad synonym: ventral abdominal ch cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001237
in subset: cur

Axiom
annotated source: ventral group abdominal chordotonal organ precursor cell
annotated property: definition
annotated target: Any chordotonal organ precursor cell (FBbt:00005216) that is part of some embryonic abdominal ventral sensory organ precursor cluster group (FBbt:00001220).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: ventral group abdominal chordotonal organ precursor cell
annotated property: hasBroadSynonym
annotated target: ventral abdominal ch cell
database_cross_reference: FlyBase:FBrf0047289

embryonic glioblast
type: Class
equivalent class: Class
  intersection of: glioblast
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: embryonic neuroblast
subclass of: glioblast
definition: Glioblast of the embryo.
database_cross_reference: VFB:FBbt_00001244
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001244
in subset: cur

Axiom
annotated source: embryonic glioblast
annotated property: definition
annotated target: Glioblast of the embryo.
database_cross_reference: FlyBase:FBrf0105240

larval glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: glial cell
subclass of: Restriction
  on property: part of
  some values from: larval nervous system
definition: Glial cell of the late embryo/larva.
database_cross_reference: VFB:FBbt_00001251
has exact synonym: embryonic/larval glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001251
in subset: cur

Axiom
annotated source: larval glial cell
annotated property: definition
annotated target: Glial cell of the late embryo/larva.
database_cross_reference: FlyBase:FBrf0050373
database_cross_reference: FlyBase:FBrf0053160
database_cross_reference: FlyBase:FBrf0054242
database_cross_reference: FlyBase:FBrf0090460
database_cross_reference: FlyBase:FBrf0098344
database_cross_reference: FlyBase:FBrf0105240
database_cross_reference: FlyBase:FBrf0205499
database_cross_reference: FlyBase:FBrf0214261

CNS surface glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: central nervous system
  intersection of: Restriction
    on property: part of
    some values from: perineurium
subclass of: CNS glial cell
subclass of: surface glial cell
definition: A glial cell that is part of (either layer of) the perineurium at the surface of the central nervous system.
has alternative id: FBbt:00001257
database_cross_reference: VFB:FBbt_00001252
has exact synonym: CNS glial cell of perineurium
has exact synonym: CNS surface associated glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001252
in subset: cur

Axiom
annotated source: CNS surface glial cell
annotated property: definition
annotated target: A glial cell that is part of (either layer of) the perineurium at the surface of the central nervous system.
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0234767
database_cross_reference: https://orcid.org/0000-0002-7073-9172

CNS glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: central nervous system
subclass of: glial cell
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Glial cell of the central nervous system.
database_cross_reference: VFB:FBbt_00001256
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001256
in subset: cur

Axiom
annotated source: CNS glial cell
annotated property: definition
annotated target: Glial cell of the central nervous system.
database_cross_reference: FlyBase:FBrf0206543

subperineurial glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: subperineurial glial sheath
subclass of: surface glial cell
subclass of: Restriction
  on property: part of
  some values from: subperineurial glial sheath
definition: Glial cell that forms the subperineurial glial sheath. These cells are polyploid. They increase in size and ploidy as the nervous system grows during development (Kremer et al., 2017).
has alternative id: FBbt:00001254
has alternative id: FBbt:00005154
has broad synonym: surface glia
database_cross_reference: VFB:FBbt_00001258
has exact synonym: SPG
has exact synonym: inner perineural sheath cell
has exact synonym: inner perineurial sheath cell
has exact synonym: subperineurial associated glial cell
has OBO namespace: fly_anatomy.ontology
has related synonym: barrier glial cell
id: FBbt:00001258
in subset: cur

Axiom
annotated source: subperineurial glial cell
annotated property: definition
annotated target: Glial cell that forms the subperineurial glial sheath. These cells are polyploid. They increase in size and ploidy as the nervous system grows during development (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0217041
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: subperineurial glial cell
annotated property: hasBroadSynonym
annotated target: surface glia
database_cross_reference: FlyBase:FBrf0082171

Axiom
annotated source: subperineurial glial cell
annotated property: hasExactSynonym
annotated target: SPG
database_cross_reference: FlyBase:FBrf0082171

Axiom
annotated source: subperineurial glial cell
annotated property: hasRelatedSynonym
annotated target: barrier glial cell
database_cross_reference: FlyBase:FBrf0058936

cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: cell body rind of the central nervous system
subclass of: CNS glial cell
subclass of: Restriction
  on property: part of
  some values from: cell body rind of the central nervous system
definition: Glial cell with a nucleus amongst the neuronal cell bodies in the cell body rind. It is irregularly shaped, with processes that enclose the neuronal cell bodies.
database_cross_reference: VFB:FBbt_00001297
has exact synonym: CBG
has exact synonym: cell body-associated glial cell
has exact synonym: cortex associated CNS glial cell
has exact synonym: cortex glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001297
in subset: cur
comment: Glial cells associated with axonal tracts (such as those associated with nerve roots) are excluded from this class of glial cells (Ito et al., 1995). Modeled as 'part of' their 'cell body rind' regions, though in practice some cell body glia have small projections into the neuropil - https://orcid.org/0000-0002-1373-1705.

Axiom
annotated source: cell body glial cell
annotated property: definition
annotated target: Glial cell with a nucleus amongst the neuronal cell bodies in the cell body rind. It is irregularly shaped, with processes that enclose the neuronal cell bodies.
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: cell body glial cell
annotated property: hasExactSynonym
annotated target: CBG
database_cross_reference: FlyBase:FBrf0082171

Axiom
annotated source: cell body glial cell
annotated property: hasExactSynonym
annotated target: cell body-associated glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: cell body glial cell
annotated property: hasExactSynonym
annotated target: cortex glial cell
database_cross_reference: FlyBase:FBrf0214261

embryonic/larval cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00049602
subclass of: cell body glial cell
subclass of: FBbt_00047861
subclass of: Restriction
  on property: part of
  some values from: FBbt_00049602
definition: Glial cell located amongst neuronal cell bodies in the cell body rind of the embryonic/larval central nervous system.
database_cross_reference: VFB:FBbt_00001298
has exact synonym: embryonic/larval cortex glial cell
has exact synonym: larval CBG
has OBO namespace: fly_anatomy.ontology
has related synonym: CoG
id: FBbt:00001298
in subset: cur

Axiom
annotated source: embryonic/larval cell body glial cell
annotated property: definition
annotated target: Glial cell located amongst neuronal cell bodies in the cell body rind of the embryonic/larval central nervous system.
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0237238

Axiom
annotated source: embryonic/larval cell body glial cell
annotated property: hasExactSynonym
annotated target: embryonic/larval cortex glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: embryonic/larval cell body glial cell
annotated property: hasExactSynonym
annotated target: larval CBG
database_cross_reference: FlyBase:FBrf0082171

neuropil glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: neuropil glial sheath
subclass of: CNS glial cell
subclass of: Restriction
  on property: overlaps
  some values from: neuropil glial sheath
definition: Glial cell of the CNS that is associated with neuropil compartments, including synaptic and tract neuropil (Hartenstein, 2011; Omoto et al., 2015; Kremer et al., 2017). These cells have their cell bodies located in the neuropil glial sheath, between the neuropil and the cell body rind, and many of them extend processes into the neuropil (Hartenstein, 2011; Omoto et al., 2015). Two subtypes have been identified, the reticular (astrocyte-like) and ensheathing glia (Hartenstein, 2011; Omoto et al., 2015), which both function in ionic and neurotransmitter homeostasis (Kremer et al., 2017).
database_cross_reference: VFB:FBbt_00001303
has exact synonym: neuropil associated CNS glial cell
has exact synonym: neuropil associated glial cell
has exact synonym: neuropil-associated CNS glial cell
has exact synonym: neuropil-associated glial cell
has exact synonym: neuropile glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001303
in subset: cur

Axiom
annotated source: neuropil glial cell
annotated property: definition
annotated target: Glial cell of the CNS that is associated with neuropil compartments, including synaptic and tract neuropil (Hartenstein, 2011; Omoto et al., 2015; Kremer et al., 2017). These cells have their cell bodies located in the neuropil glial sheath, between the neuropil and the cell body rind, and many of them extend processes into the neuropil (Hartenstein, 2011; Omoto et al., 2015). Two subtypes have been identified, the reticular (astrocyte-like) and ensheathing glia (Hartenstein, 2011; Omoto et al., 2015), which both function in ionic and neurotransmitter homeostasis (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0229106
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: neuropil glial cell
annotated property: hasExactSynonym
annotated target: neuropil associated glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: neuropil glial cell
annotated property: hasExactSynonym
annotated target: neuropil-associated glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: neuropil glial cell
annotated property: hasExactSynonym
annotated target: neuropile glial cell
database_cross_reference: FlyBase:FBrf0214261

embryonic longitudinal glial cell
type: Class
equivalent class: Class
  intersection of: FBbt_00052369
  intersection of: Restriction
    on property: develops from
    some values from: longitudinal glioblast
subclass of: CNS glial cell
subclass of: FBbt_00052369
subclass of: FBbt_00110878
subclass of: Restriction
  on property: part of
  some values from: embryonic ventral nerve cord
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00047856
subclass of: Restriction
  on property: expresses
  some values from: FBgn0011701
definition: Embryonic glial cell that is derived from the longitudinal glioblast (LGB) (Beckervordersandforth et al., 2008). It lies at the interface between the cell body rind and the synaptic neuropil of the ventral nerve cord (Ito et al., 1995). There are nine of these cells per hemineuromere in the late embryo (Ito et al., 1995; Beckervordersandforth et al., 2008). Two of these cells are produced by the first (symmetric) division of the LGB and they migrate medially (Klambt and Goodman, 1991). One of the two initial progeny differentiates into the lateral posterior longitudinal glial cell and the other divides to generate the other eight longitudinal glia (Klambt and Goodman, 1991; Peco et al., 2016). At embryonic stage 15 all of the interface glia are aligned dorsally in two rows above the longitudinal connectives (Ito et al., 1995). At early stage 16 two cells in the lateral row begin to move laterally, and one in the medial row moves ventrally along the medial border of the connective neuropil, passing by the cluster of midline glial cells (Ito et al., 1995). The ventral and lateral interface glia occupy their final (larval) positions by early stage 17 (Ito et al., 1995).
has broad synonym: embryonic neuropil cover glia
database_cross_reference: VFB:FBbt_00001311
has exact synonym: IG
has exact synonym: embryonic LG
has exact synonym: embryonic interface glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001311
in subset: cur
comment: In addition to the 8 embryonic cells (now all known to be LGB progeny) originally described by Ito et al. (1995), the "interface glia" also includes the embryonic precursor to the LP-LG (the other LGB descendant), as more recent publications use "interface glia" synonymously with "longitudinal glia" to represent all (and only) progeny of the LGB, generally preferring the term "longitudinal glia" (Beckervordersandforth et al., 2008; Omoto et al., 2015; Kato et al., 2020).

Axiom
annotated source: embryonic longitudinal glial cell
annotated property: definition
annotated target: Embryonic glial cell that is derived from the longitudinal glioblast (LGB) (Beckervordersandforth et al., 2008). It lies at the interface between the cell body rind and the synaptic neuropil of the ventral nerve cord (Ito et al., 1995). There are nine of these cells per hemineuromere in the late embryo (Ito et al., 1995; Beckervordersandforth et al., 2008). Two of these cells are produced by the first (symmetric) division of the LGB and they migrate medially (Klambt and Goodman, 1991). One of the two initial progeny differentiates into the lateral posterior longitudinal glial cell and the other divides to generate the other eight longitudinal glia (Klambt and Goodman, 1991; Peco et al., 2016). At embryonic stage 15 all of the interface glia are aligned dorsally in two rows above the longitudinal connectives (Ito et al., 1995). At early stage 16 two cells in the lateral row begin to move laterally, and one in the medial row moves ventrally along the medial border of the connective neuropil, passing by the cluster of midline glial cells (Ito et al., 1995). The ventral and lateral interface glia occupy their final (larval) positions by early stage 17 (Ito et al., 1995).
database_cross_reference: FlyBase:FBrf0054242
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0205499
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0229106
database_cross_reference: FlyBase:FBrf0231858
database_cross_reference: FlyBase:FBrf0245107

Axiom
annotated source: embryonic longitudinal glial cell
annotated property: hasBroadSynonym
annotated target: embryonic neuropil cover glia
database_cross_reference: FlyBase:FBrf0239478

Axiom
annotated source: embryonic longitudinal glial cell
annotated property: hasExactSynonym
annotated target: IG
database_cross_reference: FlyBase:FBrf0082171

Axiom
annotated source: embryonic longitudinal glial cell
annotated property: hasExactSynonym
annotated target: embryonic interface glial cell
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0205499

PNS glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: peripheral nervous system
subclass of: glial cell
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
definition: Glial cell that is part of the peripheral nervous system.
database_cross_reference: VFB:FBbt_00001320
has exact synonym: peripheral glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001320
in subset: cur

Axiom
annotated source: PNS glial cell
annotated property: definition
annotated target: Glial cell that is part of the peripheral nervous system.
database_cross_reference: FBC:SPR

embryonic neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: developing embryonic structure
subclass of: neuroblast
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval nervous system
definition: Any neuroblast of the embryo.
database_cross_reference: VFB:FBbt_00001332
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001332
in subset: cur

Axiom
annotated source: embryonic neuroblast
annotated property: definition
annotated target: Any neuroblast of the embryo.
database_cross_reference: FlyBase:FBrf0055900

procephalic neuroblast
type: Class
subclass of: neuroblast
subclass of: FBbt_00025991
subclass of: Restriction
  on property: develops from
  some values from: procephalic neurogenic region
definition: Neuroblast of one of the three procephalic regions, protocerebrum, deutocerebrum and tritocerebrum, which form the supraesophageal ganglion of the brain (Urbach et al., 2003). These neuroblasts derive from the procephalic neurogenic region (Urbach et al., 2003).
database_cross_reference: VFB:FBbt_00001333
has exact synonym: neuroblast of supraesophageal ganglion
has narrow synonym: brain neuroblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001333
in subset: cur

Axiom
annotated source: procephalic neuroblast
annotated property: definition
annotated target: Neuroblast of one of the three procephalic regions, protocerebrum, deutocerebrum and tritocerebrum, which form the supraesophageal ganglion of the brain (Urbach et al., 2003). These neuroblasts derive from the procephalic neurogenic region (Urbach et al., 2003).
database_cross_reference: FlyBase:FBrf0161021

protocerebral neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: part of
    some values from: protocerebrum
subclass of: procephalic neuroblast
subclass of: Restriction
  on property: part of
  some values from: protocerebrum
definition: A neuroblast located in the protocerebrum. None of these are serial homologues of neuroblasts found in the thoracic neuromeres (Urbach et al., 2016).
database_cross_reference: VFB:FBbt_00001334
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001334
in subset: cur
comment: In the embryo, individual neuroblasts are named according to their position relative to major morphological features (cephalic furrow, invaginating foregut, dorsal and ventral midline, their relative position with respect to each other, their time of segregation and their expression of markers) (Urbach et al., 2003).

Axiom
annotated source: protocerebral neuroblast
annotated property: definition
annotated target: A neuroblast located in the protocerebrum. None of these are serial homologues of neuroblasts found in the thoracic neuromeres (Urbach et al., 2016).
database_cross_reference: FlyBase:FBrf0089217
database_cross_reference: FlyBase:FBrf0161021
database_cross_reference: FlyBase:FBrf0232096

deutocerebral neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: part of
    some values from: deutocerebrum
subclass of: procephalic neuroblast
subclass of: Restriction
  on property: part of
  some values from: deutocerebrum
definition: A neuroblast located in the deutocerebrum. Some of these are serial homologues of neuroblasts found in the thoracic neuromeres (Urbach et al., 2016).
database_cross_reference: VFB:FBbt_00001353
has exact synonym: deuterocerebral neuroblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001353
in subset: cur
comment: In the embryo, individual neuroblasts are named according to their position relative to major morphological features (cephalic furrow, invaginating foregut, dorsal and ventral midline, their relative position with respect to each other, their time of segregation and their expression of markers) (Urbach et al., 2003).

Axiom
annotated source: deutocerebral neuroblast
annotated property: definition
annotated target: A neuroblast located in the deutocerebrum. Some of these are serial homologues of neuroblasts found in the thoracic neuromeres (Urbach et al., 2016).
database_cross_reference: FlyBase:FBrf0089217
database_cross_reference: FlyBase:FBrf0161021
database_cross_reference: FlyBase:FBrf0232096

tritocerebral neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: part of
    some values from: tritocerebrum
subclass of: procephalic neuroblast
subclass of: Restriction
  on property: part of
  some values from: tritocerebrum
definition: A neuroblast located in the tritocerebrum. Most, if not all, of these have serial homology to neuroblasts found in the thoracic neuromeres (Urbach et al., 2016). There are 13 of these, of which four produce a secondary lineage (Kuert et al., 2012; Urbach et al., 2016).
database_cross_reference: VFB:FBbt_00001363
has OBO namespace: fly_anatomy.ontology
has related synonym: T
id: FBbt:00001363
in subset: cur
comment: In the embryo, individual neuroblasts are named according to their position relative to major morphological features (cephalic furrow, invaginating foregut, dorsal and ventral midline, their relative position with respect to each other, their time of segregation and their expression of markers) (Urbach et al., 2003).

Axiom
annotated source: tritocerebral neuroblast
annotated property: definition
annotated target: A neuroblast located in the tritocerebrum. Most, if not all, of these have serial homology to neuroblasts found in the thoracic neuromeres (Urbach et al., 2016). There are 13 of these, of which four produce a secondary lineage (Kuert et al., 2012; Urbach et al., 2016).
database_cross_reference: FlyBase:FBrf0089217
database_cross_reference: FlyBase:FBrf0161021
database_cross_reference: FlyBase:FBrf0220148
database_cross_reference: FlyBase:FBrf0232096

supraesophageal ganglion neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: supraesophageal ganglion
subclass of: FBbt_00059271
subclass of: Restriction
  on property: has soma location
  some values from: supraesophageal ganglion
definition: Any neuron (FBbt:00005106) that has its soma located in some supraesophageal ganglion (FBbt:00003626).
database_cross_reference: VFB:FBbt_00001366
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001366
in subset: cur

Axiom
annotated source: supraesophageal ganglion neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some supraesophageal ganglion (FBbt:00003626).
database_cross_reference: FBC:Autogenerated

neuroblast of ventral nervous system
type: Class
subclass of: FBbt_00025993
subclass of: FBbt_00051362
subclass of: Restriction
  on property: develops from
  some values from: ventral neurectoderm
definition: Neuroblast that generates cells of the ventral nervous system, including interneurons, motor neurons and/or glial cells (Bossing et al., 1996). These neuroblasts derive from the ventral neurectoderm (Bossing et al., 1996).
database_cross_reference: VFB:FBbt_00001369
has exact synonym: VNC neuroblast
has OBO namespace: fly_anatomy.ontology
has related synonym: neuroblast of ventral nerve cord primordium
id: FBbt:00001369
in subset: EmbDevSlim
in subset: cur
comment: Applies to neuroblasts at all stages of development.

Axiom
annotated source: neuroblast of ventral nervous system
annotated property: definition
annotated target: Neuroblast that generates cells of the ventral nervous system, including interneurons, motor neurons and/or glial cells (Bossing et al., 1996). These neuroblasts derive from the ventral neurectoderm (Bossing et al., 1996).
database_cross_reference: FlyBase:FBrf0090460
database_cross_reference: FlyBase:FBrf0098344

stage 3 neuroblast
type: Class
subclass of: neuroblast
definition: A neuroblast delaminating in the third wave of neuroblast delamination from the ventral neurectoderm. This wave begins during embryonic stage 10 and end during stage 11, and the neuroblasts generally delaminate into the medial and lateral edge of the neuroblast array (Doe, 1992).
database_cross_reference: VFB:FBbt_00001393
has exact synonym: S3 NB
has OBO namespace: fly_anatomy.ontology
has related synonym: S3 neuroblast
has related synonym: SIII neuroblast
id: FBbt:00001393
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: stage 3 neuroblast
annotated property: definition
annotated target: A neuroblast delaminating in the third wave of neuroblast delamination from the ventral neurectoderm. This wave begins during embryonic stage 10 and end during stage 11, and the neuroblasts generally delaminate into the medial and lateral edge of the neuroblast array (Doe, 1992).
database_cross_reference: FlyBase:FBrf0055900
database_cross_reference: FlyBase:FBrf0076117

Axiom
annotated source: stage 3 neuroblast
annotated property: hasExactSynonym
annotated target: S3 NB
database_cross_reference: FlyBase:FBrf0055900

longitudinal glioblast
type: Class
subclass of: stage 3 neuroblast
subclass of: glioblast
subclass of: FBbt_00051362
definition: Glioblast that generates the interface (longitudinal) glia of the embryo, which become neuropil glia in the larva (Beckervordersandforth et al., 2008). It delaminates during embryonic stage 10, in the third wave of delamination (Doe, 1992). In the embryo, one of these cells can be found in each hemisegment from S2-A10 (Birkholz et al., 2013; Urbach et al., 2016). It divides once, symmetrically, to produce two glial cells (Klambt and Goodman, 1991). One of these cells appears to become the lateral posterior longitudinal glial cell and the other proliferates to generate a total of eight embryonic interface glial cells (Peco et al., 2016). It does not generate a secondary lineage (Lacin and Truman, 2016).
has broad synonym: GP
has broad synonym: glial precursor
has broad synonym: glioblast
has broad synonym: neuroblast GP
database_cross_reference: VFB:FBbt_00001405
has exact synonym: LGB
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001405
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: longitudinal glioblast
annotated property: definition
annotated target: Glioblast that generates the interface (longitudinal) glia of the embryo, which become neuropil glia in the larva (Beckervordersandforth et al., 2008). It delaminates during embryonic stage 10, in the third wave of delamination (Doe, 1992). In the embryo, one of these cells can be found in each hemisegment from S2-A10 (Birkholz et al., 2013; Urbach et al., 2016). It divides once, symmetrically, to produce two glial cells (Klambt and Goodman, 1991). One of these cells appears to become the lateral posterior longitudinal glial cell and the other proliferates to generate a total of eight embryonic interface glial cells (Peco et al., 2016). It does not generate a secondary lineage (Lacin and Truman, 2016).
database_cross_reference: FlyBase:FBrf0054242
database_cross_reference: FlyBase:FBrf0055900
database_cross_reference: FlyBase:FBrf0205499
database_cross_reference: FlyBase:FBrf0221210
database_cross_reference: FlyBase:FBrf0231327
database_cross_reference: FlyBase:FBrf0231858
database_cross_reference: FlyBase:FBrf0232096

Axiom
annotated source: longitudinal glioblast
annotated property: hasBroadSynonym
annotated target: GP
database_cross_reference: FlyBase:FBrf0049007

Axiom
annotated source: longitudinal glioblast
annotated property: hasBroadSynonym
annotated target: glial precursor
database_cross_reference: FlyBase:FBrf0049007

Axiom
annotated source: longitudinal glioblast
annotated property: hasBroadSynonym
annotated target: glioblast
database_cross_reference: FlyBase:FBrf0050676

Axiom
annotated source: longitudinal glioblast
annotated property: hasExactSynonym
annotated target: LGB
database_cross_reference: FlyBase:FBrf0205499

larval neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: larval nervous system
definition: Neuron that is part of the larval nervous system. Neurons with functional roles in the larva are born during the embryonic phase of neurogenesis and further neurons, with adult-specific roles, are born during the postembryonic phase, which begins during larval development (Lacin and Truman, 2016).
database_cross_reference: VFB:FBbt_00001446
has exact synonym: embryonic/larval neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001446
in subset: cur
comment: This includes immature secondary neurons that are found in the larva - https://orcid.org/0000-0002-1373-1705.

Axiom
annotated source: larval neuron
annotated property: definition
annotated target: Neuron that is part of the larval nervous system. Neurons with functional roles in the larva are born during the embryonic phase of neurogenesis and further neurons, with adult-specific roles, are born during the postembryonic phase, which begins during larval development (Lacin and Truman, 2016).
database_cross_reference: FlyBase:FBrf0090460
database_cross_reference: FlyBase:FBrf0098344
database_cross_reference: FlyBase:FBrf0231327

antennal lobe tract
type: Class
subclass of: FBbt_00007426
subclass of: Restriction
  on property: innervates
  some values from: protocerebrum
subclass of: Restriction
  on property: innervates
  some values from: antennal lobe
definition: A tract connecting the antennal lobe to various neuropils of the protocerebrum.
has alternative id: FBbt:00007123
database_cross_reference: VFB:FBbt_00001635
has exact synonym: ACT
has exact synonym: ALT
has exact synonym: antenno-cerebral tract
has exact synonym: antennocerebral tract
has exact synonym: antennoglomerular tract
has exact synonym: antennoprotocerebral tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001635
in subset: cur

Axiom
annotated source: antennal lobe tract
annotated property: definition
annotated target: A tract connecting the antennal lobe to various neuropils of the protocerebrum.
database_cross_reference: FlyBase:FBrf0051437
database_cross_reference: FlyBase:FBrf0155899
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: antennal lobe tract
annotated property: hasExactSynonym
annotated target: antennoprotocerebral tract
database_cross_reference: FlyBase:FBrf0211016

embryonic imaginal tissue
type: Class
equivalent class: Class
  intersection of: FBbt_00047552
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: developing embryonic structure
subclass of: FBbt_00047552
definition: Embryonic structure that will develop into a larval imaginal tissue, which will later form an adult structure (Cohen, 1993).
database_cross_reference: UBERON:6001648
has exact synonym: embryonic imaginal precursor
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001648
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic imaginal tissue
annotated property: definition
annotated target: Embryonic structure that will develop into a larval imaginal tissue, which will later form an adult structure (Cohen, 1993).
database_cross_reference: FlyBase:FBrf0064789

imaginal disc primordium
type: Class
subclass of: embryonic imaginal tissue
subclass of: primordium
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral epidermis primordium
subclass of: Restriction
  on property: develops into
  some values from: imaginal disc
definition: Population of contiguous, morphologically distinct cells of the embryo that will proliferate to form an imaginal disc in the larva. During early embryogenesis the precursor is part of the epithelial sheet before segregating from the epithelial sheet by late embryogenesis (Cohen, 1993).
database_cross_reference: UBERON:6001649
has OBO namespace: fly_anatomy.ontology
has related synonym: imaginal disc specific anlage
id: FBbt:00001649
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: imaginal disc primordium
annotated property: definition
annotated target: Population of contiguous, morphologically distinct cells of the embryo that will proliferate to form an imaginal disc in the larva. During early embryogenesis the precursor is part of the epithelial sheet before segregating from the epithelial sheet by late embryogenesis (Cohen, 1993).
database_cross_reference: FBC:SPR
database_cross_reference: FlyBase:FBrf0064789

eye-antennal disc primordium
type: Class
subclass of: imaginal disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic antennal segment
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops into
  some values from: eye-antennal disc
definition: Primordium from which the eye-antennal disc develops.
database_cross_reference: UBERON:6001652
has OBO namespace: fly_anatomy.ontology
has related synonym: eye-antennal disc specific anlage
id: FBbt:00001652
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: eye-antennal disc primordium
annotated property: definition
annotated target: Primordium from which the eye-antennal disc develops.
database_cross_reference: FBC:SPR

dorsal thoracic disc primordium
type: Class
subclass of: imaginal disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic segment
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048408
subclass of: Restriction
  on property: develops into
  some values from: dorsal thoracic disc
definition: Primordium of the embryo that will develop into a dorsal thoracic disc.
database_cross_reference: UBERON:6001653
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal thoracic disc specific anlage
id: FBbt:00001653
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: dorsal thoracic disc primordium
annotated property: definition
annotated target: Primordium of the embryo that will develop into a dorsal thoracic disc.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

dorsal prothoracic disc primordium
type: Class
equivalent class: Class
  intersection of: dorsal thoracic disc primordium
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: dorsal thoracic disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic prothoracic segment
subclass of: Restriction
  on property: develops into
  some values from: humeral disc
definition: Any dorsal thoracic disc primordium (FBbt:00001653) that is part of some prothoracic segment (FBbt:00000017).
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal prothoracic disc specific anlage
id: FBbt:00001654
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: dorsal prothoracic disc primordium
annotated property: definition
annotated target: Any dorsal thoracic disc primordium (FBbt:00001653) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

dorsal mesothoracic disc primordium
type: Class
equivalent class: Class
  intersection of: dorsal thoracic disc primordium
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: dorsal thoracic disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic mesothoracic segment
subclass of: Restriction
  on property: develops into
  some values from: wing disc
definition: Any dorsal thoracic disc primordium (FBbt:00001653) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: UBERON:6001655
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal mesothoracic disc specific anlage
id: FBbt:00001655
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: dorsal mesothoracic disc primordium
annotated property: definition
annotated target: Any dorsal thoracic disc primordium (FBbt:00001653) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: FBC:Autogenerated

dorsal metathoracic disc primordium
type: Class
equivalent class: Class
  intersection of: dorsal thoracic disc primordium
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: dorsal thoracic disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic metathoracic segment
subclass of: Restriction
  on property: develops into
  some values from: haltere disc
definition: Any dorsal thoracic disc primordium (FBbt:00001653) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: UBERON:6001656
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal metathoracic disc specific anlage
id: FBbt:00001656
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: dorsal metathoracic disc primordium
annotated property: definition
annotated target: Any dorsal thoracic disc primordium (FBbt:00001653) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: FBC:Autogenerated

ventral thoracic disc primordium
type: Class
subclass of: imaginal disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic thoracic segment
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048408
subclass of: Restriction
  on property: develops into
  some values from: leg disc
definition: Primordium of the embryo that will develop into a ventral thoracic (leg) disc.
database_cross_reference: UBERON:6001657
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral thoracic disc specific anlage
id: FBbt:00001657
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral thoracic disc primordium
annotated property: definition
annotated target: Primordium of the embryo that will develop into a ventral thoracic (leg) disc.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

ventral prothoracic disc primordium
type: Class
equivalent class: Class
  intersection of: ventral thoracic disc primordium
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: ventral thoracic disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic prothoracic segment
subclass of: Restriction
  on property: develops into
  some values from: prothoracic leg disc
definition: Any ventral thoracic disc primordium (FBbt:00001657) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: UBERON:6001658
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral prothoracic disc specific anlage
id: FBbt:00001658
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral prothoracic disc primordium
annotated property: definition
annotated target: Any ventral thoracic disc primordium (FBbt:00001657) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

ventral mesothoracic disc primordium
type: Class
equivalent class: Class
  intersection of: ventral thoracic disc primordium
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: ventral thoracic disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic mesothoracic segment
subclass of: Restriction
  on property: develops into
  some values from: mesothoracic leg disc
definition: Any ventral thoracic disc primordium (FBbt:00001657) that is part of some mesothoracic segment (FBbt:00000018).
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral mesothoracic disc specific anlage
id: FBbt:00001659
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral mesothoracic disc primordium
annotated property: definition
annotated target: Any ventral thoracic disc primordium (FBbt:00001657) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: FBC:Autogenerated

ventral metathoracic disc primordium
type: Class
equivalent class: Class
  intersection of: ventral thoracic disc primordium
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: ventral thoracic disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic metathoracic segment
subclass of: Restriction
  on property: develops into
  some values from: metathoracic leg disc
definition: Any ventral thoracic disc primordium (FBbt:00001657) that is part of some metathoracic segment (FBbt:00000019).
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral metathoracic disc specific anlage
id: FBbt:00001660
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral metathoracic disc primordium
annotated property: definition
annotated target: Any ventral thoracic disc primordium (FBbt:00001657) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: FBC:Autogenerated

genital disc primordium
type: Class
subclass of: imaginal disc primordium
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops into
  some values from: genital disc
definition: Primordium from which the genital disc develops.
database_cross_reference: UBERON:6001661
has OBO namespace: fly_anatomy.ontology
has related synonym: genital disc specific anlage
id: FBbt:00001661
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: genital disc primordium
annotated property: definition
annotated target: Primordium from which the genital disc develops.
database_cross_reference: FBC:SPR

male genital disc primordium
type: Class
subclass of: genital disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal segment 9
subclass of: Restriction
  on property: develops into
  some values from: male genital disc
definition: Primordium from which the male genital disc derives.
database_cross_reference: UBERON:6001662
has OBO namespace: fly_anatomy.ontology
has related synonym: male genital disc specific anlage
id: FBbt:00001662
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: male genital disc primordium
annotated property: definition
annotated target: Primordium from which the male genital disc derives.
database_cross_reference: FBC:SPR

female genital disc primordium
type: Class
subclass of: genital disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic abdominal segment 8
subclass of: Restriction
  on property: develops into
  some values from: female genital disc
definition: Primordium from which the female genital disc derives.
database_cross_reference: UBERON:6001663
has OBO namespace: fly_anatomy.ontology
has related synonym: female genital disc specific anlage
id: FBbt:00001663
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: female genital disc primordium
annotated property: definition
annotated target: Primordium from which the female genital disc derives.
database_cross_reference: FBC:SPR

larval circulatory system
type: Class
equivalent class: Class
  intersection of: circulatory system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: circulatory system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Tubular system of the late embryo and larva through which hemolymph flows.
has alternative id: FBbt:00005677
database_cross_reference: UBERON:6001664
has exact synonym: embryonic/larval circulatory system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001664
in subset: cur

Axiom
annotated source: larval circulatory system
annotated property: definition
annotated target: Tubular system of the late embryo and larva through which hemolymph flows.
database_cross_reference: FlyBase:FBrf0031012

embryonic/larval dorsal vessel
type: Class
equivalent class: Class
  intersection of: FBbt_00058291
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: FBbt_00058291
subclass of: Restriction
  on property: part of
  some values from: larval circulatory system
definition: A contractile tube in the embryo/larva that extends from immediately behind the posterior commissure of T1 to the arthrodial membrane of A7, into which it inserts via two caudally directed muscles which connect to lateral apodemes in A8. Throughout its length, its lumen is enclosed by just two cardial cells. This single-cell thick layer of cardial cells is surrounded by a single-cell thick layer of pericardial cells, except in the posterior thorax. In this region, it is surrounded by lymph gland in the anterior thorax where it passes through the ring gland. The whole tube is attached to the anterior region of each abdominal segment boundary by alary muscles.
has alternative id: FBbt:00005681
has exact synonym: larval dorsal vessel
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001673
in subset: cur

Axiom
annotated source: embryonic/larval dorsal vessel
annotated property: definition
annotated target: A contractile tube in the embryo/larva that extends from immediately behind the posterior commissure of T1 to the arthrodial membrane of A7, into which it inserts via two caudally directed muscles which connect to lateral apodemes in A8. Throughout its length, its lumen is enclosed by just two cardial cells. This single-cell thick layer of cardial cells is surrounded by a single-cell thick layer of pericardial cells, except in the posterior thorax. In this region, it is surrounded by lymph gland in the anterior thorax where it passes through the ring gland. The whole tube is attached to the anterior region of each abdominal segment boundary by alary muscles.
database_cross_reference: FlyBase:FBrf0089570

embryonic/larval hemocyte
type: Class
equivalent class: Class
  intersection of: hemocyte
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: hemocyte
subclass of: Restriction
  on property: part of
  some values from: larval circulatory system
definition: Blood cell of the embryo or larva that is involved in the cellular immune response.
has alternative id: FBbt:00005701
has exact synonym: embryonic/larval blood cell
has exact synonym: embryonic/larval haemocyte
has exact synonym: larval hemocyte
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001684
in subset: cur

Axiom
annotated source: embryonic/larval hemocyte
annotated property: definition
annotated target: Blood cell of the embryo or larva that is involved in the cellular immune response.
database_cross_reference: FlyBase:FBrf0037631

abdominal larval oenocyte group
type: Class
subclass of: portion of tissue
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: larval abdomen
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00017020
definition: A cluster of 4-9 larval oenocytes situated bilaterally in each of abdominal segments 1-7 in a space between the dorsoventral muscles and the body wall. Each cell group is closely associated with an 'abdominal lateral pentascolopidial chordotonal organ lch5' and is supplied by its own tracheal branch.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001695
in subset: cur

Axiom
annotated source: abdominal larval oenocyte group
annotated property: definition
annotated target: A cluster of 4-9 larval oenocytes situated bilaterally in each of abdominal segments 1-7 in a space between the dorsoventral muscles and the body wall. Each cell group is closely associated with an 'abdominal lateral pentascolopidial chordotonal organ lch5' and is supplied by its own tracheal branch.
database_cross_reference: FlyBase:FBrf0007734
database_cross_reference: FlyBase:FBrf0134578

abdominal 6 larval oenocyte group
type: Class
equivalent class: Class
  intersection of: abdominal larval oenocyte group
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 6
subclass of: abdominal larval oenocyte group
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 6
definition: Any abdominal larval oenocyte group (FBbt:00001695) that is part of some abdominal segment 6 (FBbt:00000027).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001701
in subset: cur

Axiom
annotated source: abdominal 6 larval oenocyte group
annotated property: definition
annotated target: Any abdominal larval oenocyte group (FBbt:00001695) that is part of some abdominal segment 6 (FBbt:00000027).
database_cross_reference: FBC:Autogenerated

larval adipose system
type: Class
equivalent class: Class
  intersection of: adipose system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: adipose system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Adipose system of the late embryo/larva.
has alternative id: FBbt:00005709
has exact synonym: embryonic/larval adipose system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001703
in subset: cur

Axiom
annotated source: larval adipose system
annotated property: definition
annotated target: Adipose system of the late embryo/larva.
database_cross_reference: FBC:SPR

embryonic/larval fat body
type: Class
equivalent class: Class
  intersection of: fat body
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: fat body
subclass of: somatic trunk mesoderm derivative
subclass of: Restriction
  on property: part of
  some values from: larval adipose system
subclass of: Restriction
  on property: develops from
  some values from: fat body primordium
definition: Fully developed fat body of the late embryo (from stage 17 onward) or the larva. It is a bilateral, multilobed organ that extends the length of the insect (Butterworth et al., 1965). It is one cell thick and between one and ten cells wide (Butterworth et al., 1965). Large holes and clefts form during stage 17, giving the fat body its definitive larval form (Campos-Ortega and Hartenstein, 1997).
has alternative id: FBbt:00005711
has exact synonym: larval fat body
has exact synonym: larval fatbody
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001704
in subset: cur

Axiom
annotated source: embryonic/larval fat body
annotated property: definition
annotated target: Fully developed fat body of the late embryo (from stage 17 onward) or the larva. It is a bilateral, multilobed organ that extends the length of the insect (Butterworth et al., 1965). It is one cell thick and between one and ten cells wide (Butterworth et al., 1965). Large holes and clefts form during stage 17, giving the fat body its definitive larval form (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0017184
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0238315

Axiom
annotated source: embryonic/larval fat body
annotated property: hasExactSynonym
annotated target: larval fat body
database_cross_reference: FlyBase:FBrf0238315

Axiom
annotated source: embryonic/larval fat body
annotated property: hasExactSynonym
annotated target: larval fatbody
database_cross_reference: FlyBase:FBrf0016348

larval endocrine system
type: Class
equivalent class: Class
  intersection of: endocrine system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: endocrine system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Endocrine system of the late embryo/larva.
has alternative id: FBbt:00005713
has exact synonym: embryonic/larval endocrine system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001715
in subset: cur

Axiom
annotated source: larval endocrine system
annotated property: definition
annotated target: Endocrine system of the late embryo/larva.
database_cross_reference: FBC:SPR

corpus allatum primordium
type: Class
subclass of: FBbt_00017009
subclass of: FBbt_00026000
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: cardiogenic mesoderm
subclass of: Restriction
  on property: develops into
  some values from: embryonic/larval corpus allatum
definition: The primordium that will form the embryonic/larval corpus allatum, a substructure of the embryonic/larval ring gland. It is a paired structure that becomes distinct in early dorsal closure between the head mesoderm and the epidermis of the gnathal segments. During dorsal closure the paired primordia move dorsally to meet and fuse above the cardioblasts of the developing aorta.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic corpus allatum
id: FBbt:00001716
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: corpus allatum primordium
annotated property: definition
annotated target: The primordium that will form the embryonic/larval corpus allatum, a substructure of the embryonic/larval ring gland. It is a paired structure that becomes distinct in early dorsal closure between the head mesoderm and the epidermis of the gnathal segments. During dorsal closure the paired primordia move dorsally to meet and fuse above the cardioblasts of the developing aorta.
database_cross_reference: FlyBase:FBrf0089570

corpus cardiacum primordium
type: Class
subclass of: FBbt_00017009
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops into
  some values from: embryonic/larval corpus cardiacum
definition: The corpora cardiaca precursor first appear during stage 10 as two pairs of head mesoderm cells between the roof of the stomodeum and the inner surface of the brain primordium that derive from the anterior lip of the ventral furrow. Between stages 11 and 15, these cells migrate posteriorly, gradually increasing in number. During stage 15, they fuse with the precursors of the corpus allatum from the gnathal mesoderm to form the ring gland.
has alternative id: FBbt:00001720
has OBO namespace: fly_anatomy.ontology
has related synonym: P1 CC
has related synonym: corpus cardiacum placode
has related synonym: embryonic corpus cardiacum
id: FBbt:00001717
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: corpus cardiacum primordium
annotated property: definition
annotated target: The corpora cardiaca precursor first appear during stage 10 as two pairs of head mesoderm cells between the roof of the stomodeum and the inner surface of the brain primordium that derive from the anterior lip of the ventral furrow. Between stages 11 and 15, these cells migrate posteriorly, gradually increasing in number. During stage 15, they fuse with the precursors of the corpus allatum from the gnathal mesoderm to form the ring gland.
database_cross_reference: FlyBase:FBrf0179777

Axiom
annotated source: corpus cardiacum primordium
annotated property: hasRelatedSynonym
annotated target: P1 CC
database_cross_reference: https://orcid.org/0000-0002-7073-9172

retrocerebral complex
type: Class
subclass of: FBbt_00007229
subclass of: Restriction
  on property: part of
  some values from: ring gland
definition: The endocrine complex which consists of the corpus cardiacum and corpus allatum (Hartenstein, 2006; Lee et al., 2008).
database_cross_reference: UBERON:0012325
has exact synonym: CC-CA
has exact synonym: retrocerebral neuroendocrine complex
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001718
in subset: cur
comment: This is the common part of the adult (CA, CC, HG) and larval (CA, CC, PG) ring glands, but terminology seems to be very rarely used for the larva - https://orcid.org/0000-0002-1373-1705.

Axiom
annotated source: retrocerebral complex
annotated property: definition
annotated target: The endocrine complex which consists of the corpus cardiacum and corpus allatum (Hartenstein, 2006; Lee et al., 2008).
database_cross_reference: FlyBase:FBrf0194938
database_cross_reference: FlyBase:FBrf0204201
database_cross_reference: FlyBase:FBrf0239029

Axiom
annotated source: retrocerebral complex
annotated property: hasExactSynonym
annotated target: CC-CA
database_cross_reference: FlyBase:FBrf0204742

Axiom
annotated source: retrocerebral complex
annotated property: hasExactSynonym
annotated target: retrocerebral neuroendocrine complex
database_cross_reference: FlyBase:FBrf0187136

ring gland
type: Class
subclass of: FBbt_00007277
subclass of: FBbt_00007435
definition: A cluster that surrounds the aorta, dorsal to the esophagus. It is composed of the corpus allatum (CA), corpus cardiacum (CC) and the prothoracic gland in the larva and the CA, CC and hypocerebral ganglion in the adult (Hartenstein, 1993). In the larva it is found anterior to the brain (Dai and Gilbert, 1991). The gland migrates posteriorly during pupal stages and the larval prothoracic gland degenerates (Dai and Gilbert, 1991). In the adult it is found posterior to the brain, just anterior to the proventriculus (Nassel and Zandawala, 2020).
database_cross_reference: UBERON:6001722
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001722
in subset: FB gloss
in subset: cur

Axiom
annotated source: ring gland
annotated property: definition
annotated target: A cluster that surrounds the aorta, dorsal to the esophagus. It is composed of the corpus allatum (CA), corpus cardiacum (CC) and the prothoracic gland in the larva and the CA, CC and hypocerebral ganglion in the adult (Hartenstein, 1993). In the larva it is found anterior to the brain (Dai and Gilbert, 1991). The gland migrates posteriorly during pupal stages and the larval prothoracic gland degenerates (Dai and Gilbert, 1991). In the adult it is found posterior to the brain, just anterior to the proventriculus (Nassel and Zandawala, 2020).
database_cross_reference: FlyBase:FBrf0053727
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0179777
database_cross_reference: FlyBase:FBrf0239029
database_cross_reference: FlyBase:FBrf0247015

prothoracic gland
type: Class
subclass of: neurohemal organ
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: FBbt_00049277
subclass of: Restriction
  on property: continuous with
  some values from: embryonic/larval corpus allatum
subclass of: Restriction
  on property: continuous with
  some values from: embryonic/larval corpus cardiacum
subclass of: Restriction
  on property: develops from
  some values from: prothoracic gland primordium
definition: Component of the larval ring gland that is continuous with the corpus cardiacum at its ventroposterior end, encircles the aorta, and surrounds the medially-located corpus allatum at its dorsoanterior end (Dai and Gilbert, 1991; de Velasco et al., 2004; Nassel and Zandawala, 2020). It is composed of very few cells in the late embryo, but these increase in size and number during larval development (de Velasco et al., 2004). It produces ecdysone and is most active in the early wandering third instar (Dai and Gilbert, 1991; Nassel and Zandawala, 2020). During pupal development, its cells separate, shrink and degenerate and none are found attached to the adult corpus allatum or corpus cardiacum after eclosion (Dai and Gilbert, 1991).
has exact synonym: PTG
has exact synonym: thoracic gland
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001724
in subset: cur

Axiom
annotated source: prothoracic gland
annotated property: definition
annotated target: Component of the larval ring gland that is continuous with the corpus cardiacum at its ventroposterior end, encircles the aorta, and surrounds the medially-located corpus allatum at its dorsoanterior end (Dai and Gilbert, 1991; de Velasco et al., 2004; Nassel and Zandawala, 2020). It is composed of very few cells in the late embryo, but these increase in size and number during larval development (de Velasco et al., 2004). It produces ecdysone and is most active in the early wandering third instar (Dai and Gilbert, 1991; Nassel and Zandawala, 2020). During pupal development, its cells separate, shrink and degenerate and none are found attached to the adult corpus allatum or corpus cardiacum after eclosion (Dai and Gilbert, 1991).
database_cross_reference: FlyBase:FBrf0053727
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0179777
database_cross_reference: FlyBase:FBrf0247015

Axiom
annotated source: prothoracic gland
annotated property: hasExactSynonym
annotated target: PTG
database_cross_reference: FlyBase:FBrf0247015

Axiom
annotated source: prothoracic gland
annotated property: hasExactSynonym
annotated target: thoracic gland
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570

embryonic/larval corpus allatum
type: Class
subclass of: corpus allatum
subclass of: FBbt_00026000
subclass of: Restriction
  on property: part of
  some values from: gnathal segment
subclass of: Restriction
  on property: part of
  some values from: FBbt_00049635
subclass of: Restriction
  on property: continuous with
  some values from: prothoracic gland
subclass of: Restriction
  on property: develops from
  some values from: corpus allatum primordium
definition: Neurohemal organ found medially in the anterodorsal part of the larval ring gland, surrounded by cells of the prothoracic gland (Dai and Gilbert, 1991; de Velasco et al., 2004). It is composed of smaller cells than the prothoracic gland (Dai and Gilbert, 1991). It produces juvenile hormone (Dai and Gilbert, 1991; Hartenstein, 1993).
has alternative id: FBbt:00001719
has exact synonym: larval corpus allatum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001725
in subset: cur

Axiom
annotated source: embryonic/larval corpus allatum
annotated property: definition
annotated target: Neurohemal organ found medially in the anterodorsal part of the larval ring gland, surrounded by cells of the prothoracic gland (Dai and Gilbert, 1991; de Velasco et al., 2004). It is composed of smaller cells than the prothoracic gland (Dai and Gilbert, 1991). It produces juvenile hormone (Dai and Gilbert, 1991; Hartenstein, 1993).
database_cross_reference: FlyBase:FBrf0053727
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0179777

embryonic/larval corpus cardiacum
type: Class
subclass of: corpus cardiacum
subclass of: Restriction
  on property: part of
  some values from: gnathal segment
subclass of: Restriction
  on property: part of
  some values from: FBbt_00049635
subclass of: Restriction
  on property: continuous with
  some values from: prothoracic gland
subclass of: Restriction
  on property: develops from
  some values from: corpus cardiacum primordium
definition: Region of the larval ring gland closest to the brain that forms a U-shape around the floor of the aorta (Dai and Gilbert, 1991; de Velasco et al., 2004). It is connected to the brain by the nervi corporis cardiaci, which carry axons of secretory neurons that release neuropeptides in this location (Dirksen et al., 2008). It produces Adipokinetic hormone (Lee and Park, 2004) and sequesters insulin-like peptides released by insulin secreting cells of the pars intercerebralis (Ghosh et al., 2022). These two hormones are packaged into the same secretory vesicles (Ghosh et al., 2022).
has exact synonym: larval corpus cardiacum
has OBO namespace: fly_anatomy.ontology
has related synonym: corpora cardiacum
id: FBbt:00001726
in subset: cur

Axiom
annotated source: embryonic/larval corpus cardiacum
annotated property: definition
annotated target: Region of the larval ring gland closest to the brain that forms a U-shape around the floor of the aorta (Dai and Gilbert, 1991; de Velasco et al., 2004). It is connected to the brain by the nervi corporis cardiaci, which carry axons of secretory neurons that release neuropeptides in this location (Dirksen et al., 2008). It produces Adipokinetic hormone (Lee and Park, 2004) and sequesters insulin-like peptides released by insulin secreting cells of the pars intercerebralis (Ghosh et al., 2022). These two hormones are packaged into the same secretory vesicles (Ghosh et al., 2022).
database_cross_reference: FlyBase:FBrf0053727
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0178933
database_cross_reference: FlyBase:FBrf0179777
database_cross_reference: FlyBase:FBrf0204742
database_cross_reference: FlyBase:FBrf0253296

larva
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: embryo
definition: Organism during the period between hatching and prepupa formation.
database_cross_reference: UBERON:0002548
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001727
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: larva
annotated property: definition
annotated target: Organism during the period between hatching and prepupa formation.
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0089570

larval tagma
type: Class
equivalent class: Class
  intersection of: tagma
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: tagma
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Any tagma of the larva.
database_cross_reference: UBERON:6001728
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001728
in subset: cur

Axiom
annotated source: larval tagma
annotated property: definition
annotated target: Any tagma of the larva.
database_cross_reference: FBC:Autogenerated

larval segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: larva
subclass of: Restriction
  on property: develops from
  some values from: embryonic segment
definition: Any segment of the larva.
database_cross_reference: UBERON:6001729
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001729
in subset: cur
in subset: larval OF

Axiom
annotated source: larval segment
annotated property: definition
annotated target: Any segment of the larva.
database_cross_reference: FBC:Autogenerated

larval head
type: Class
equivalent class: Class
  intersection of: head
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: head
subclass of: larval tagma
definition: Any head of the larva.
database_cross_reference: UBERON:6001730
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001730
in subset: cur
in subset: larval OF

Axiom
annotated source: larval head
annotated property: definition
annotated target: Any head of the larva.
database_cross_reference: FBC:Autogenerated

larval ocular segment
type: Class
equivalent class: Class
  intersection of: ocular segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: ocular segment
subclass of: larval procephalic segment
definition: Any ocular segment of the larva.
database_cross_reference: UBERON:6001731
has OBO namespace: fly_anatomy.ontology
has related synonym: larval acron
id: FBbt:00001731
in subset: cur

Axiom
annotated source: larval ocular segment
annotated property: definition
annotated target: Any ocular segment of the larva.
database_cross_reference: FBC:Autogenerated

larval head segment
type: Class
equivalent class: Class
  intersection of: head segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: head segment
subclass of: larval segment
subclass of: Restriction
  on property: part of
  some values from: larval head
definition: Any head segment of the larva.
database_cross_reference: UBERON:6001732
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001732
in subset: cur
in subset: larval OF

Axiom
annotated source: larval head segment
annotated property: definition
annotated target: Any head segment of the larva.
database_cross_reference: FlyBase:FBrf0075072

larval procephalic segment
type: Class
equivalent class: Class
  intersection of: procephalic segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: procephalic segment
subclass of: larval head segment
definition: Any procephalic segment of the larva.
database_cross_reference: UBERON:6001733
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001733
in subset: cur
in subset: larval OF

Axiom
annotated source: larval procephalic segment
annotated property: definition
annotated target: Any procephalic segment of the larva.
database_cross_reference: FBC:Autogenerated

larval labral segment
type: Class
equivalent class: Class
  intersection of: labral segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: labral segment
subclass of: larval procephalic segment
definition: Any labral segment of the larva.
database_cross_reference: UBERON:6001734
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001734
in subset: cur
in subset: larval OF

Axiom
annotated source: larval labral segment
annotated property: definition
annotated target: Any labral segment of the larva.
database_cross_reference: FBC:Autogenerated

larval antennal segment
type: Class
equivalent class: Class
  intersection of: antennal segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: antennal segment
subclass of: larval procephalic segment
definition: Any antennal segment of the larva.
database_cross_reference: UBERON:6001735
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001735
in subset: cur
in subset: larval OF

Axiom
annotated source: larval antennal segment
annotated property: definition
annotated target: Any antennal segment of the larva.
database_cross_reference: FBC:Autogenerated

larval intercalary segment
type: Class
equivalent class: Class
  intersection of: intercalary segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: intercalary segment
subclass of: larval procephalic segment
definition: Any intercalary segment of the larva.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001736
in subset: cur

Axiom
annotated source: larval intercalary segment
annotated property: definition
annotated target: Any intercalary segment of the larva.
database_cross_reference: FBC:Autogenerated

larval gnathal segment
type: Class
equivalent class: Class
  intersection of: gnathal segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: gnathal segment
subclass of: larval head segment
definition: Any gnathal segment of the larva.
database_cross_reference: UBERON:6001737
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001737
in subset: cur

Axiom
annotated source: larval gnathal segment
annotated property: definition
annotated target: Any gnathal segment of the larva.
database_cross_reference: FBC:Autogenerated

larval mandibular segment
type: Class
equivalent class: Class
  intersection of: mandibular segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: mandibular segment
subclass of: larval gnathal segment
definition: Any mandibular segment of the larva.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001738
in subset: cur

Axiom
annotated source: larval mandibular segment
annotated property: definition
annotated target: Any mandibular segment of the larva.
database_cross_reference: FBC:Autogenerated

larval maxillary segment
type: Class
equivalent class: Class
  intersection of: maxillary segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: maxillary segment
subclass of: larval gnathal segment
definition: Any maxillary segment of the larva.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001739
in subset: cur

Axiom
annotated source: larval maxillary segment
annotated property: definition
annotated target: Any maxillary segment of the larva.
database_cross_reference: FBC:Autogenerated

larval labial segment
type: Class
equivalent class: Class
  intersection of: labial segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: labial segment
subclass of: larval gnathal segment
definition: Any labial segment of the larva.
database_cross_reference: UBERON:6001740
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001740
in subset: cur

Axiom
annotated source: larval labial segment
annotated property: definition
annotated target: Any labial segment of the larva.
database_cross_reference: FBC:Autogenerated

larval thorax
type: Class
equivalent class: Class
  intersection of: thorax
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: thorax
subclass of: larval tagma
definition: Any thorax of the larva.
database_cross_reference: UBERON:6001741
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001741
in subset: cur

Axiom
annotated source: larval thorax
annotated property: definition
annotated target: Any thorax of the larva.
database_cross_reference: FBC:Autogenerated

larval thoracic segment
type: Class
equivalent class: Class
  intersection of: thoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: thoracic segment
subclass of: larval segment
subclass of: Restriction
  on property: part of
  some values from: larval thorax
definition: Any thoracic segment of the larva.
database_cross_reference: UBERON:6001742
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001742
in subset: cur

Axiom
annotated source: larval thoracic segment
annotated property: definition
annotated target: Any thoracic segment of the larva.
database_cross_reference: FBC:Autogenerated

larval prothoracic segment
type: Class
equivalent class: Class
  intersection of: prothoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: prothoracic segment
subclass of: larval thoracic segment
definition: Any prothoracic segment of the larva.
database_cross_reference: UBERON:6001743
has OBO namespace: fly_anatomy.ontology
has related synonym: prothorax
has related synonym: t1
has related synonym: thoracic segment 1
id: FBbt:00001743
in subset: cur

Axiom
annotated source: larval prothoracic segment
annotated property: definition
annotated target: Any prothoracic segment of the larva.
database_cross_reference: FBC:Autogenerated

larval mesothoracic segment
type: Class
equivalent class: Class
  intersection of: mesothoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: mesothoracic segment
subclass of: larval thoracic segment
definition: Any mesothoracic segment of the larva.
database_cross_reference: UBERON:6001744
has OBO namespace: fly_anatomy.ontology
has related synonym: mesothorax
has related synonym: t2
has related synonym: thoracic segment 2
id: FBbt:00001744
in subset: cur

Axiom
annotated source: larval mesothoracic segment
annotated property: definition
annotated target: Any mesothoracic segment of the larva.
database_cross_reference: FBC:Autogenerated

larval metathoracic segment
type: Class
equivalent class: Class
  intersection of: metathoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: metathoracic segment
subclass of: larval thoracic segment
definition: Any metathoracic segment of the larva.
database_cross_reference: UBERON:6001745
has OBO namespace: fly_anatomy.ontology
has related synonym: metathorax
has related synonym: t3
has related synonym: thoracic segment 3
id: FBbt:00001745
in subset: cur

Axiom
annotated source: larval metathoracic segment
annotated property: definition
annotated target: Any metathoracic segment of the larva.
database_cross_reference: FBC:Autogenerated

larval abdomen
type: Class
equivalent class: Class
  intersection of: abdomen
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: abdomen
subclass of: larval tagma
definition: Any abdomen of the larva.
database_cross_reference: UBERON:6001746
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001746
in subset: cur

Axiom
annotated source: larval abdomen
annotated property: definition
annotated target: Any abdomen of the larva.
database_cross_reference: FBC:Autogenerated

larval abdominal segment
type: Class
equivalent class: Class
  intersection of: abdominal segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: abdominal segment
subclass of: larval segment
subclass of: Restriction
  on property: part of
  some values from: larval abdomen
definition: Any abdominal segment of the larva.
database_cross_reference: UBERON:6001747
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001747
in subset: cur

Axiom
annotated source: larval abdominal segment
annotated property: definition
annotated target: Any abdominal segment of the larva.
database_cross_reference: FBC:Autogenerated

larval abdominal segment 6
type: Class
equivalent class: Class
  intersection of: abdominal segment 6
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: abdominal segment 6
subclass of: FBbt_00110209
definition: Any abdominal segment 6 of the larva.
has OBO namespace: fly_anatomy.ontology
has related synonym: a6
id: FBbt:00001753
in subset: cur

Axiom
annotated source: larval abdominal segment 6
annotated property: definition
annotated target: Any abdominal segment 6 of the larva.
database_cross_reference: FBC:Autogenerated

larval abdominal segment 8
type: Class
equivalent class: Class
  intersection of: abdominal segment 8
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: abdominal segment 8
subclass of: FBbt_00052389
subclass of: Restriction
  on property: overlaps
  some values from: larval telson
definition: Any abdominal segment 8 of the larva.
database_cross_reference: UBERON:6001755
has OBO namespace: fly_anatomy.ontology
has related synonym: a8
id: FBbt:00001755
in subset: cur

Axiom
annotated source: larval abdominal segment 8
annotated property: definition
annotated target: Any abdominal segment 8 of the larva.
database_cross_reference: FBC:Autogenerated

larval abdominal segment 9
type: Class
equivalent class: Class
  intersection of: abdominal segment 9
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: abdominal segment 9
subclass of: FBbt_00052389
subclass of: Restriction
  on property: part of
  some values from: larval telson
definition: Any abdominal segment 9 of the larva.
database_cross_reference: UBERON:6001756
has OBO namespace: fly_anatomy.ontology
has related synonym: a9
id: FBbt:00001756
in subset: cur

Axiom
annotated source: larval abdominal segment 9
annotated property: definition
annotated target: Any abdominal segment 9 of the larva.
database_cross_reference: FBC:Autogenerated

larval abdominal segment 11
type: Class
equivalent class: Class
  intersection of: abdominal segment 11
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: abdominal segment 11
subclass of: FBbt_00052389
subclass of: Restriction
  on property: part of
  some values from: larval telson
definition: Rudimentary larval abdominal segment that surrounds the anal opening.
has OBO namespace: fly_anatomy.ontology
has related synonym: a11
id: FBbt:00001758
in subset: cur

Axiom
annotated source: larval abdominal segment 11
annotated property: definition
annotated target: Rudimentary larval abdominal segment that surrounds the anal opening.
database_cross_reference: FlyBase:FBrf0064788

larval telson
type: Class
equivalent class: Class
  intersection of: telson
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: telson
subclass of: Restriction
  on property: part of
  some values from: larval abdomen
definition: Any telson of the larva.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001759
in subset: cur

Axiom
annotated source: larval telson
annotated property: definition
annotated target: Any telson of the larva.
database_cross_reference: FBC:Autogenerated

larval imaginal tissue
type: Class
equivalent class: Class
  intersection of: FBbt_00047552
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: FBbt_00047552
subclass of: Restriction
  on property: part of
  some values from: larva
subclass of: Restriction
  on property: develops from
  some values from: embryonic imaginal tissue
definition: Imaginal tissue that is found in the larva and will develop into an adult structure during metamorphosis.
database_cross_reference: UBERON:6001760
has exact synonym: embryonic/larval imaginal precursor
has exact synonym: larval imaginal precursor
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001760
in subset: cur

Axiom
annotated source: larval imaginal tissue
annotated property: definition
annotated target: Imaginal tissue that is found in the larva and will develop into an adult structure during metamorphosis.
database_cross_reference: FlyBase:FBrf0064789

imaginal disc
type: Class
subclass of: larval imaginal tissue
subclass of: multi-tissue structure
subclass of: FBbt_00025993
subclass of: Restriction
  on property: develops from
  some values from: imaginal disc primordium
definition: A sac shaped epithelial structure in the larva that gives rise to part of the adult integumentary system. One side of the sac consists of peripodial epithelium, the other of columnar epithelium. A single anterior-posterior compartment boundary bisects both peripodial membrane and columnar epithelium. Cells do not cross this boundary during growth and development of the disc.
database_cross_reference: UBERON:0000939
has OBO namespace: fly_anatomy.ontology
has related synonym: imaginal disk
id: FBbt:00001761
in subset: FB gloss
in subset: cur

Axiom
annotated source: imaginal disc
annotated property: definition
annotated target: A sac shaped epithelial structure in the larva that gives rise to part of the adult integumentary system. One side of the sac consists of peripodial epithelium, the other of columnar epithelium. A single anterior-posterior compartment boundary bisects both peripodial membrane and columnar epithelium. Cells do not cross this boundary during growth and development of the disc.
database_cross_reference: FBC:GG

eye-antennal disc
type: Class
subclass of: imaginal disc
subclass of: Restriction
  on property: develops from
  some values from: eye-antennal disc primordium
definition: Imaginal disc that, in the adults, gives rise to the eye, antenna, head capsule (including all bristles and external membranes) and the maxillary palps (Cohen, 1993).
database_cross_reference: UBERON:6001766
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001766
in subset: EmbDevSlim
in subset: cur
comment: Figure 12 from Cohen (1993, Bate, Martinez Arias, 1993: 747--841) provides a fate map of the eye-antennal disc.

Axiom
annotated source: eye-antennal disc
annotated property: definition
annotated target: Imaginal disc that, in the adults, gives rise to the eye, antenna, head capsule (including all bristles and external membranes) and the maxillary palps (Cohen, 1993).
database_cross_reference: FlyBase:FBrf0064789

antennal disc
type: Class
subclass of: imaginal disc
subclass of: Restriction
  on property: part of
  some values from: larval antennal segment
subclass of: Restriction
  on property: part of
  some values from: eye-antennal disc
definition: Posterior portion of the eye-antennal disc. It gives rise to the adult antennal segments and the maxillary palp, as well as contributing to the head capsule.
database_cross_reference: UBERON:6001767
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001767
in subset: cur
comment: Figure 12 from Cohen (1993, Bate, Martinez Arias, 1993: 747--841) provides a fate map of the eye-antennal disc.

Axiom
annotated source: antennal disc
annotated property: definition
annotated target: Posterior portion of the eye-antennal disc. It gives rise to the adult antennal segments and the maxillary palp, as well as contributing to the head capsule.
database_cross_reference: FlyBase:FBrf0064789

eye disc
type: Class
subclass of: imaginal disc
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: eye-antennal disc
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00105515
definition: Anterior, bulbous portion of the eye-antennal disc that gives rise to the eye as well as contributing to the head capsule (Cohen, 1993).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001768
in subset: cur
comment: Figure 12 from Cohen (1993, Bate, Martinez Arias, 1993: 747--841) provides a fate map of the eye-antennal disc.

Axiom
annotated source: eye disc
annotated property: definition
annotated target: Anterior, bulbous portion of the eye-antennal disc that gives rise to the eye as well as contributing to the head capsule (Cohen, 1993).
database_cross_reference: FlyBase:FBrf0064789

ommatidial precursor cluster
type: Class
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: eye disc posterior to the morphogenetic furrow
subclass of: Restriction
  on property: develops into
  some values from: ommatidium
definition: A cluster of cells in the eye-disc that is the precursor to an adult ommatidium. Eventually there are approximately 750 ommatidial precursor clusters per eye-disc, the first forming at approximately 70hrs before pupation along the morphogenic furrow. A new row of adult ommatidial precursors then emerges from the morphogenic furrow roughly every 1.5 hours.
has OBO namespace: fly_anatomy.ontology
has related synonym: ommatidial cluster
id: FBbt:00001770
in subset: cur

Axiom
annotated source: ommatidial precursor cluster
annotated property: definition
annotated target: A cluster of cells in the eye-disc that is the precursor to an adult ommatidium. Eventually there are approximately 750 ommatidial precursor clusters per eye-disc, the first forming at approximately 70hrs before pupation along the morphogenic furrow. A new row of adult ommatidial precursors then emerges from the morphogenic furrow roughly every 1.5 hours.
database_cross_reference: FlyBase:FBrf0064798

dorsal thoracic disc
type: Class
subclass of: imaginal disc
subclass of: Restriction
  on property: part of
  some values from: larval thoracic segment
subclass of: Restriction
  on property: develops from
  some values from: dorsal thoracic disc primordium
definition: Imaginal disc that is a precursor of dorsal thoracic structures of the adult.
database_cross_reference: UBERON:6001776
has exact synonym: dorsal thoracic disk
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001776
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: dorsal thoracic disc
annotated property: definition
annotated target: Imaginal disc that is a precursor of dorsal thoracic structures of the adult.
database_cross_reference: FlyBase:FBrf0064789
database_cross_reference: FlyBase:FBrf0064803

humeral disc
type: Class
equivalent class: Class
  intersection of: dorsal thoracic disc
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: dorsal thoracic disc
subclass of: Restriction
  on property: part of
  some values from: larval prothoracic segment
subclass of: Restriction
  on property: develops from
  some values from: dorsal prothoracic disc primordium
definition: Dorsal imaginal disc of the prothoracic segment that is the precursor of structures of the adult dorsal prothorax including the humerus.
has exact synonym: dorsal prothoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001777
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: humeral disc
annotated property: definition
annotated target: Dorsal imaginal disc of the prothoracic segment that is the precursor of structures of the adult dorsal prothorax including the humerus.
database_cross_reference: FlyBase:FBrf0064789

wing disc
type: Class
equivalent class: Class
  intersection of: dorsal thoracic disc
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: dorsal thoracic disc
subclass of: Restriction
  on property: part of
  some values from: larval mesothoracic segment
subclass of: Restriction
  on property: develops from
  some values from: dorsal mesothoracic disc primordium
definition: Dorsal imaginal disc of the mesothorax. Precursor of dorsal mesothoracic structures of the adult including the postnotum, scutum, scutellum, wing, wing hinge and part of the notal pleura.
database_cross_reference: UBERON:6001778
has exact synonym: dorsal mesothoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001778
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: wing disc
annotated property: definition
annotated target: Dorsal imaginal disc of the mesothorax. Precursor of dorsal mesothoracic structures of the adult including the postnotum, scutum, scutellum, wing, wing hinge and part of the notal pleura.
database_cross_reference: FlyBase:FBrf0064789

haltere disc
type: Class
equivalent class: Class
  intersection of: dorsal thoracic disc
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: dorsal thoracic disc
subclass of: Restriction
  on property: part of
  some values from: larval metathoracic segment
subclass of: Restriction
  on property: develops from
  some values from: dorsal metathoracic disc primordium
definition: Dorsal imaginal disc of the metathorax. Precursor of structure of the adult dorsal metathorax including the haltere.
database_cross_reference: UBERON:6001779
has exact synonym: dorsal metathoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001779
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: haltere disc
annotated property: definition
annotated target: Dorsal imaginal disc of the metathorax. Precursor of structure of the adult dorsal metathorax including the haltere.
database_cross_reference: FlyBase:FBrf0064789

leg disc
type: Class
subclass of: imaginal disc
subclass of: Restriction
  on property: part of
  some values from: larval thoracic segment
subclass of: Restriction
  on property: develops from
  some values from: ventral thoracic disc primordium
definition: Imaginal disc that is a precursor of a leg (a ventral thoracic structure of the adult).
database_cross_reference: UBERON:6001780
has exact synonym: ventral thoracic disc
has exact synonym: ventral thoracic disk
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001780
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: leg disc
annotated property: definition
annotated target: Imaginal disc that is a precursor of a leg (a ventral thoracic structure of the adult).
database_cross_reference: FlyBase:FBrf0064789
database_cross_reference: FlyBase:FBrf0064803

prothoracic leg disc
type: Class
equivalent class: Class
  intersection of: leg disc
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: leg disc
subclass of: Restriction
  on property: part of
  some values from: larval prothoracic segment
subclass of: Restriction
  on property: develops from
  some values from: ventral prothoracic disc primordium
definition: Imaginal disc of the ventral prothoracic segment. Precursor of structures of the adult ventral prothorax including the prothoracic (1st) leg.
database_cross_reference: UBERON:6001781
has exact synonym: 1st leg disc
has exact synonym: T1 leg disc
has exact synonym: ventral prothoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001781
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: prothoracic leg disc
annotated property: definition
annotated target: Imaginal disc of the ventral prothoracic segment. Precursor of structures of the adult ventral prothorax including the prothoracic (1st) leg.
database_cross_reference: FlyBase:FBrf0064789

mesothoracic leg disc
type: Class
equivalent class: Class
  intersection of: leg disc
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: leg disc
subclass of: Restriction
  on property: part of
  some values from: larval mesothoracic segment
subclass of: Restriction
  on property: develops from
  some values from: ventral mesothoracic disc primordium
definition: Imaginal disc of the ventral mesothoracic segment. Precursor of structures of the adult ventral mesothorax including the mesothoracic (2nd) leg.
has exact synonym: 2nd leg disc
has exact synonym: T2 leg disc
has exact synonym: ventral mesothoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001782
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: mesothoracic leg disc
annotated property: definition
annotated target: Imaginal disc of the ventral mesothoracic segment. Precursor of structures of the adult ventral mesothorax including the mesothoracic (2nd) leg.
database_cross_reference: FlyBase:FBrf0064789

metathoracic leg disc
type: Class
equivalent class: Class
  intersection of: leg disc
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: leg disc
subclass of: Restriction
  on property: part of
  some values from: larval metathoracic segment
subclass of: Restriction
  on property: develops from
  some values from: ventral metathoracic disc primordium
definition: Imaginal disc of the ventral metathoracic segment. Precursor of structures of the adult ventral metathorax including the metathoracic (3rd) leg.
has exact synonym: 3rd leg disc
has exact synonym: T3 leg disc
has exact synonym: ventral metathoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001783
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: metathoracic leg disc
annotated property: definition
annotated target: Imaginal disc of the ventral metathoracic segment. Precursor of structures of the adult ventral metathorax including the metathoracic (3rd) leg.
database_cross_reference: FlyBase:FBrf0064789

genital disc
type: Class
subclass of: imaginal disc
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002451
subclass of: Restriction
  on property: develops from
  some values from: genital disc primordium
definition: Imaginal disc that gives rise to the internal and external genitalia, analia and adult hindgut (Cohen, 1993). It is located just anterior to the anus of the larva, connected to the epidermis by a thick stalk at the posterior of the disc (Epper and Nothiger, 1982).
database_cross_reference: UBERON:6001784
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001784
in subset: cur

Axiom
annotated source: genital disc
annotated property: definition
annotated target: Imaginal disc that gives rise to the internal and external genitalia, analia and adult hindgut (Cohen, 1993). It is located just anterior to the anus of the larva, connected to the epidermis by a thick stalk at the posterior of the disc (Epper and Nothiger, 1982).
database_cross_reference: FlyBase:FBrf0037847
database_cross_reference: FlyBase:FBrf0064789

male genital disc
type: Class
subclass of: genital disc
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 9
subclass of: Restriction
  on property: develops from
  some values from: male genital disc primordium
definition: Genital disc that gives rise to the penis and external genitalia, sperm pump, ejaculatory duct, paragonia and vas deferens, anal plates and adult hindgut (Cohen, 1993).
database_cross_reference: UBERON:6001785
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001785
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: male genital disc
annotated property: definition
annotated target: Genital disc that gives rise to the penis and external genitalia, sperm pump, ejaculatory duct, paragonia and vas deferens, anal plates and adult hindgut (Cohen, 1993).
database_cross_reference: FlyBase:FBrf0064789

male genital primordium (female)
type: Class
equivalent class: Class
  intersection of: FBbt_00052053
  intersection of: Restriction
    on property: part of
    some values from: female organism
subclass of: repressed genital primordium
subclass of: FBbt_00052053
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: female accessory gland duct
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00052060
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00052079
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00052080
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00052082
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00052083
subclass of: Restriction
  on property: part of
  some values from: female genital disc
subclass of: Restriction
  on property: part of
  some values from: female organism
definition: Male genital primordium of the female genital disc. it does not expand much during larval development and constitutes a relatively small part of the disc.
has exact synonym: RMP
has exact synonym: female repressed primordium
has exact synonym: repressed male genital primordium
has exact synonym: rmp
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001786
in subset: cur

Axiom
annotated source: male genital primordium (female)
annotated property: definition
annotated target: Male genital primordium of the female genital disc. it does not expand much during larval development and constitutes a relatively small part of the disc.
database_cross_reference: FlyBase:FBrf0037847
database_cross_reference: FlyBase:FBrf0040174
database_cross_reference: FlyBase:FBrf0064788
database_cross_reference: FlyBase:FBrf0091028
database_cross_reference: FlyBase:FBrf0141451

Axiom
annotated source: male genital primordium (female)
annotated property: hasExactSynonym
annotated target: RMP
database_cross_reference: FlyBase:FBrf0037847

Axiom
annotated source: male genital primordium (female)
annotated property: hasExactSynonym
annotated target: repressed male genital primordium
database_cross_reference: FlyBase:FBrf0037847

Axiom
annotated source: male genital primordium (female)
annotated property: hasExactSynonym
annotated target: rmp
database_cross_reference: FlyBase:FBrf0091028

female genital disc
type: Class
subclass of: genital disc
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 8
subclass of: Restriction
  on property: develops from
  some values from: female genital disc primordium
definition: Genital disc that gives rise to the vagina and vaginal plates, uterus, parovaria, spermatheca, seminal recepticle, oviducts, female analia and hindgut. (Cohen, 1993).
database_cross_reference: UBERON:6001787
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001787
in subset: cur

Axiom
annotated source: female genital disc
annotated property: definition
annotated target: Genital disc that gives rise to the vagina and vaginal plates, uterus, parovaria, spermatheca, seminal recepticle, oviducts, female analia and hindgut. (Cohen, 1993).
database_cross_reference: FlyBase:FBrf0064789

female genital primordium (male)
type: Class
equivalent class: Class
  intersection of: FBbt_00052052
  intersection of: Restriction
    on property: part of
    some values from: male organism
subclass of: repressed genital primordium
subclass of: FBbt_00052052
subclass of: Restriction
  on property: part of
  some values from: male genital disc
subclass of: Restriction
  on property: part of
  some values from: male organism
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00048382
definition: Female genital primordium of the male genital disc. it does not expand much during larval development and constitutes a relatively small part of the disc.
has exact synonym: RFP
has exact synonym: male repressed primordium
has exact synonym: repressed female genital primordium
has exact synonym: rfp
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001788
in subset: cur

Axiom
annotated source: female genital primordium (male)
annotated property: definition
annotated target: Female genital primordium of the male genital disc. it does not expand much during larval development and constitutes a relatively small part of the disc.
database_cross_reference: FlyBase:FBrf0037847
database_cross_reference: FlyBase:FBrf0064788
database_cross_reference: FlyBase:FBrf0091028
database_cross_reference: FlyBase:FBrf0141451

Axiom
annotated source: female genital primordium (male)
annotated property: hasExactSynonym
annotated target: RFP
database_cross_reference: FlyBase:FBrf0037847

Axiom
annotated source: female genital primordium (male)
annotated property: hasExactSynonym
annotated target: repressed female genital primordium
database_cross_reference: FlyBase:FBrf0037847

Axiom
annotated source: female genital primordium (male)
annotated property: hasExactSynonym
annotated target: rfp
database_cross_reference: FlyBase:FBrf0091028

histoblast
type: Class
subclass of: somatic precursor cell
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: histoblast nest
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00016022
definition: A progenitor cell found in the larval epidermis that produces the adult external abdomen. These cells are part of the larval epidermis, secrete cuticle and contribute to larval epithelial patterning. They can be distinguished from the larval epidermal cells due to their small size and the fact that they remain diploid (Martinez Arias, 1993).
database_cross_reference: CL:0000373
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001789
in subset: cur

Axiom
annotated source: histoblast
annotated property: definition
annotated target: A progenitor cell found in the larval epidermis that produces the adult external abdomen. These cells are part of the larval epidermis, secrete cuticle and contribute to larval epithelial patterning. They can be distinguished from the larval epidermal cells due to their small size and the fact that they remain diploid (Martinez Arias, 1993).
database_cross_reference: FlyBase:FBrf0064786

histoblast nest
type: Class
subclass of: larval imaginal tissue
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval epidermis
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00016022
definition: One of several groups of histoblasts in the epidermis of the larval abdomen that gives rise to part of the adult external abdomen during metamorphosis.
database_cross_reference: UBERON:6001790
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001790
in subset: FB gloss
in subset: cur

Axiom
annotated source: histoblast nest
annotated property: definition
annotated target: One of several groups of histoblasts in the epidermis of the larval abdomen that gives rise to part of the adult external abdomen during metamorphosis.
database_cross_reference: FlyBase:FBrf0064786

dorsal histoblast nest abdominal
type: Class
subclass of: histoblast nest
subclass of: dorsal imaginal tissue
definition: One of two histoblast nests per abdominal hemisegment (found in A1-A7). It is located in a dorsal position in the epidermis of the larval abdomen.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001791
in subset: cur

Axiom
annotated source: dorsal histoblast nest abdominal
annotated property: definition
annotated target: One of two histoblast nests per abdominal hemisegment (found in A1-A7). It is located in a dorsal position in the epidermis of the larval abdomen.
database_cross_reference: FlyBase:FBrf0064786

anterior dorsal histoblast nest abdominal
type: Class
subclass of: dorsal histoblast nest abdominal
definition: Bilaterally-paired histoblast nest found in the epidermis of abdominal segments 1-7. This nest is found in an anterior dorsal position and contains approximately 15 cells.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001792
in subset: cur

Axiom
annotated source: anterior dorsal histoblast nest abdominal
annotated property: definition
annotated target: Bilaterally-paired histoblast nest found in the epidermis of abdominal segments 1-7. This nest is found in an anterior dorsal position and contains approximately 15 cells.
database_cross_reference: FlyBase:FBrf0064786

anterior dorsal histoblast nest abdominal 6
type: Class
equivalent class: Class
  intersection of: anterior dorsal histoblast nest abdominal
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 6
subclass of: anterior dorsal histoblast nest abdominal
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 6
definition: Bilaterally-paired histoblast nest found in the epidermis of abdominal segment 6. This nest is found in an anterior dorsal position and contains approximately 15 cells.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001804
in subset: cur

Axiom
annotated source: anterior dorsal histoblast nest abdominal 6
annotated property: definition
annotated target: Bilaterally-paired histoblast nest found in the epidermis of abdominal segment 6. This nest is found in an anterior dorsal position and contains approximately 15 cells.
database_cross_reference: FlyBase:FBrf0064786

anterior dorsal histoblast nest abdominal 8
type: Class
equivalent class: Class
  intersection of: anterior dorsal histoblast nest abdominal
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 8
subclass of: anterior dorsal histoblast nest abdominal
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 8
definition: Histoblast nest located in an anterior dorsal position of abdominal segment 8.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001808
in subset: cur
comment: According to Martinez Arias, 1993 (FBrf0064786), the histoblast nests are only found in abdominal segments 1-7, so this nest does not exist - https://orcid.org/0000-0002-1373-1705.

posterior dorsal histoblast nest abdominal
type: Class
subclass of: dorsal histoblast nest abdominal
definition: Bilaterally-paired histoblast nest found in the epidermis of abdominal segments 1-7. This nest is found in a posterior dorsal position and contains approximately 6 cells.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001809
in subset: cur

Axiom
annotated source: posterior dorsal histoblast nest abdominal
annotated property: definition
annotated target: Bilaterally-paired histoblast nest found in the epidermis of abdominal segments 1-7. This nest is found in a posterior dorsal position and contains approximately 6 cells.
database_cross_reference: FlyBase:FBrf0064786

posterior dorsal histoblast nest abdominal 6
type: Class
equivalent class: Class
  intersection of: posterior dorsal histoblast nest abdominal
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 6
subclass of: posterior dorsal histoblast nest abdominal
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 6
definition: Bilaterally-paired histoblast nest found in the epidermis of abdominal segment 6. This nest is found in a posterior dorsal position and contains approximately 6 cells.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001815
in subset: cur

Axiom
annotated source: posterior dorsal histoblast nest abdominal 6
annotated property: definition
annotated target: Bilaterally-paired histoblast nest found in the epidermis of abdominal segment 6. This nest is found in a posterior dorsal position and contains approximately 6 cells.
database_cross_reference: FlyBase:FBrf0064786

posterior dorsal histoblast nest abdominal 8
type: Class
equivalent class: Class
  intersection of: posterior dorsal histoblast nest abdominal
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 8
subclass of: posterior dorsal histoblast nest abdominal
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 8
definition: Histoblast nest found in a posterior dorsal position in the epidermis of abdominal segment 8.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001817
in subset: cur
comment: According to Martinez Arias, 1993 (FBrf0064786), the histoblast nests are only found in abdominal segments 1-7, so this nest does not exist - https://orcid.org/0000-0002-1373-1705.

imaginal ring
type: Class
subclass of: larval imaginal tissue
definition: A ring shaped structure in the larva that gives rise to part of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001834
in subset: cur

Axiom
annotated source: imaginal ring
annotated property: definition
annotated target: A ring shaped structure in the larva that gives rise to part of the adult.
database_cross_reference: FlyBase:FBrf0064792

salivary gland imaginal ring
type: Class
subclass of: imaginal ring
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval salivary gland
subclass of: Restriction
  on property: develops from
  some values from: embryonic primordium of adult salivary gland
definition: Ring of imaginal cells situated where the larval salivary glands join the salivary ducts, from which the adult salivary glands develop.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001835
in subset: cur

Axiom
annotated source: salivary gland imaginal ring
annotated property: definition
annotated target: Ring of imaginal cells situated where the larval salivary glands join the salivary ducts, from which the adult salivary glands develop.
database_cross_reference: FlyBase:FBrf0064786
database_cross_reference: FlyBase:FBrf0064792

foregut imaginal ring
type: Class
subclass of: imaginal ring
subclass of: FBbt_00025991
subclass of: FBbt_00100315
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval foregut
subclass of: Restriction
  on property: develops from
  some values from: embryonic precursor of adult foregut
definition: Ring of imaginal tissue located in the embryonic/larval gut, at the junction of the foregut and midgut epithelia in the anterior part of the proventriculus. It is the precursor of the posterior region of the adult foregut.
has OBO namespace: fly_anatomy.ontology
has related synonym: proventriculus imaginal ring
id: FBbt:00001836
in subset: cur

Axiom
annotated source: foregut imaginal ring
annotated property: definition
annotated target: Ring of imaginal tissue located in the embryonic/larval gut, at the junction of the foregut and midgut epithelia in the anterior part of the proventriculus. It is the precursor of the posterior region of the adult foregut.
database_cross_reference: FlyBase:FBrf0007733
database_cross_reference: FlyBase:FBrf0064792

midgut imaginal island
type: Class
subclass of: larval imaginal tissue
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval midgut
subclass of: Restriction
  on property: has part
  some values from: adult midgut progenitor cell
subclass of: Restriction
  on property: has part
  some values from: FBbt_00110875
definition: A cluster consisting of adult midgut precursor cells and peripheral cells found adjacent to the basement membrane of the larval midgut. These clusters are scattered throughout the larval midgut. They form by division of adult midgut precursor cells during larval stages. The first division is asymmetrical, producing a peripheral cell, which extends its processes around the adult midgut precursor cells (Mathur et al., 2010).
has OBO namespace: fly_anatomy.ontology
has related synonym: midgut imaginal histoblasts
id: FBbt:00001837
in subset: cur

Axiom
annotated source: midgut imaginal island
annotated property: definition
annotated target: A cluster consisting of adult midgut precursor cells and peripheral cells found adjacent to the basement membrane of the larval midgut. These clusters are scattered throughout the larval midgut. They form by division of adult midgut precursor cells during larval stages. The first division is asymmetrical, producing a peripheral cell, which extends its processes around the adult midgut precursor cells (Mathur et al., 2010).
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0209706

larval hindgut imaginal ring
type: Class
subclass of: imaginal ring
subclass of: FBbt_00025992
subclass of: FBbt_00100315
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval hindgut
subclass of: Restriction
  on property: develops from
  some values from: embryonic precursor of adult hindgut
definition: Ring of imaginal tissue located at the anterior region of the embryonic/larval hindgut, posterior to where the Malpighian tubules join the hindgut, from which the adult hindgut forms. The hindgut imaginal ring cells are densely clustered, appear immature and have little cytoplasm (Murakami and Shiotsuki, 2001).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001840
in subset: cur

Axiom
annotated source: larval hindgut imaginal ring
annotated property: definition
annotated target: Ring of imaginal tissue located at the anterior region of the embryonic/larval hindgut, posterior to where the Malpighian tubules join the hindgut, from which the adult hindgut forms. The hindgut imaginal ring cells are densely clustered, appear immature and have little cytoplasm (Murakami and Shiotsuki, 2001).
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0135849

anal imaginal ring
type: Class
subclass of: imaginal ring
subclass of: FBbt_00025992
subclass of: FBbt_00100315
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 11
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval anus
subclass of: Restriction
  on property: develops from
  some values from: embryonic precursor of adult hindgut
definition: Imaginal tissue of the larva from which the adult anus develops.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001841
in subset: cur

Axiom
annotated source: anal imaginal ring
annotated property: definition
annotated target: Imaginal tissue of the larva from which the adult anus develops.
database_cross_reference: FlyBase:FBrf0064792

larval digestive system
type: Class
equivalent class: Class
  intersection of: digestive system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: digestive system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Any digestive system of the larva.
has alternative id: FBbt:00005764
database_cross_reference: UBERON:6001842
has exact synonym: embryonic/larval digestive system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001842
in subset: cur

Axiom
annotated source: larval digestive system
annotated property: definition
annotated target: Any digestive system of the larva.
database_cross_reference: FlyBase:FBrf0007733
database_cross_reference: FlyBase:FBrf0064792

embryonic/larval cibarium
type: Class
subclass of: dorsal ectoderm derivative
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: antennal segment
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval pharynx
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00017019
definition: Posterior portion of the embryonic/larval pharynx, posterior to the atrium.
has alternative id: FBbt:00005766
has exact synonym: embryonic/larval atrium
has exact synonym: larval cibarium
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001844
in subset: cur
comment: Jurgens et al. (1986) define the larval cibarium as being the same as the pharynx, and posterior to the atrium. However, Campos-Ortega and Hartenstein (1985) define it as being the same as the atrium, and anterior to the pharynx. We follow the latter. mc140708.

Axiom
annotated source: embryonic/larval cibarium
annotated property: definition
annotated target: Posterior portion of the embryonic/larval pharynx, posterior to the atrium.
database_cross_reference: FlyBase:FBrf0041814
database_cross_reference: FlyBase:FBrf0045366

Axiom
annotated source: embryonic/larval cibarium
annotated property: hasExactSynonym
annotated target: embryonic/larval atrium
database_cross_reference: FlyBase:FBrf0041814

embryonic/larval foregut
type: Class
subclass of: foregut
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007512
subclass of: Restriction
  on property: develops from
  some values from: embryonic foregut
definition: Anterior-most part of the embryonic/larval alimentary canal. It opens anteriorly at the mouth and is composed of the atrium (to which the salivary glands are attached), the pharynx, and the esophagus and part of the proventriculus.
has alternative id: FBbt:00005768
has exact synonym: foreintestine
has exact synonym: larval foregut
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001862
in subset: cur

Axiom
annotated source: embryonic/larval foregut
annotated property: definition
annotated target: Anterior-most part of the embryonic/larval alimentary canal. It opens anteriorly at the mouth and is composed of the atrium (to which the salivary glands are attached), the pharynx, and the esophagus and part of the proventriculus.
database_cross_reference: FlyBase:FBrf0064792

Axiom
annotated source: embryonic/larval foregut
annotated property: hasExactSynonym
annotated target: foreintestine
database_cross_reference: FlyBase:FBrf0007733

embryonic/larval pharynx
type: Class
subclass of: pharynx
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval foregut
definition: Region of the embryonic/larval foregut between the atrium and the esophagus. It consists of a bulbous epithelial tube associated with an elaborate chitinous skeleton and musculature. The anterior edge of the pharynx is delimited ventrally by the opening of the salivary gland common duct and dorsally by the median tooth of the mouth hooks. The posterior edge is delimited by the narrowing of the foregut that marks the beginning of the esophagus.
has alternative id: FBbt:00005769
has exact synonym: larval pharynx
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001866
in subset: cur
comment: Bodenstein, 1950, uses the term pharynx to refer to the entire anterior portion of the larval foregut, which in this ontology is divided into the atrium (anterior) and pharynx (posterior).

Axiom
annotated source: embryonic/larval pharynx
annotated property: definition
annotated target: Region of the embryonic/larval foregut between the atrium and the esophagus. It consists of a bulbous epithelial tube associated with an elaborate chitinous skeleton and musculature. The anterior edge of the pharynx is delimited ventrally by the opening of the salivary gland common duct and dorsally by the median tooth of the mouth hooks. The posterior edge is delimited by the narrowing of the foregut that marks the beginning of the esophagus.
database_cross_reference: FlyBase:FBrf0089570

embryonic/larval salivary gland
type: Class
subclass of: salivary gland
subclass of: Restriction
  on property: part of
  some values from: larval digestive system
subclass of: Restriction
  on property: develops from
  some values from: presumptive embryonic salivary gland
definition: Salivary gland of the embryo/larva.
has alternative id: FBbt:00005717
has exact synonym: larval salivary gland
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001878
in subset: cur

Axiom
annotated source: embryonic/larval salivary gland
annotated property: definition
annotated target: Salivary gland of the embryo/larva.
database_cross_reference: FBC:SPR

embryonic/larval salivary gland duct
type: Class
subclass of: FBbt_00025993
subclass of: FBbt_00100314
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval salivary gland
subclass of: Restriction
  on property: develops from
  some values from: salivary gland duct primordium
definition: Y-shaped tube that carries the secretions from the salivary glands to the embryonic/larval mouth.
has alternative id: FBbt:00005774
has exact synonym: larval salivary gland duct
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001880
in subset: cur

Axiom
annotated source: embryonic/larval salivary gland duct
annotated property: definition
annotated target: Y-shaped tube that carries the secretions from the salivary glands to the embryonic/larval mouth.
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0159337

embryonic/larval salivary gland common duct
type: Class
subclass of: FBbt_00025993
subclass of: FBbt_00100314
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval salivary gland duct
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00016005
definition: Anterior length of the salivary gland duct. Anteriorly it connects to the atrium of the foregut. Posteriorly it bifurcates into the ducts of the individual salivary glands (Skaer, 1993).
has alternative id: FBbt:00005775
has exact synonym: larval salivary gland common duct
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001881
in subset: cur

Axiom
annotated source: embryonic/larval salivary gland common duct
annotated property: definition
annotated target: Anterior length of the salivary gland duct. Anteriorly it connects to the atrium of the foregut. Posteriorly it bifurcates into the ducts of the individual salivary glands (Skaer, 1993).
database_cross_reference: FlyBase:FBrf0064792

embryonic/larval midgut
type: Class
subclass of: midgut
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007512
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00007593
definition: Middle part of the embryonic/larval alimentary canal. The midgut runs from the proventriculus to its posterior end, where it meets the hindgut, immediately anterior to the insertion of the Malpighian tubules. In the larva, there are the 4 gastric caeca at the anterior end.
has alternative id: FBbt:00005825
has exact synonym: larval midgut
has exact synonym: midintestine
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001882
in subset: cur

Axiom
annotated source: embryonic/larval midgut
annotated property: definition
annotated target: Middle part of the embryonic/larval alimentary canal. The midgut runs from the proventriculus to its posterior end, where it meets the hindgut, immediately anterior to the insertion of the Malpighian tubules. In the larva, there are the 4 gastric caeca at the anterior end.
database_cross_reference: FlyBase:FBrf0064792

Axiom
annotated source: embryonic/larval midgut
annotated property: hasExactSynonym
annotated target: midintestine
database_cross_reference: FlyBase:FBrf0007733

embryonic/larval midgut cell
type: Class
equivalent class: Class
  intersection of: FBbt_00100318
  intersection of: Restriction
    on property: part of
    some values from: embryonic/larval midgut
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval midgut
definition: Cell of the embryonic or larval midgut.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001886
in subset: cur

Axiom
annotated source: embryonic/larval midgut cell
annotated property: definition
annotated target: Cell of the embryonic or larval midgut.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic/larval hindgut
type: Class
subclass of: hindgut
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007512
definition: Posterior part of the embryonic/larval alimentary canal, composed of pylorus (anterior), ileum and rectum (posterior) (Cohen et al., 2020).
has alternative id: FBbt:00005826
has exact synonym: hindintestine
has exact synonym: larval hindgut
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001891
in subset: cur

Axiom
annotated source: embryonic/larval hindgut
annotated property: definition
annotated target: Posterior part of the embryonic/larval alimentary canal, composed of pylorus (anterior), ileum and rectum (posterior) (Cohen et al., 2020).
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0244771

Axiom
annotated source: embryonic/larval hindgut
annotated property: hasExactSynonym
annotated target: hindintestine
database_cross_reference: FlyBase:FBrf0007733

embryonic/larval rectum
type: Class
subclass of: rectum
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval hindgut
subclass of: Restriction
  on property: develops from
  some values from: rectum primordium
definition: Posterior-most portion of the embryonic/larval alimentary canal, terminating in the anus.
has alternative id: FBbt:00005779
has exact synonym: larval rectum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001892
in subset: cur

Axiom
annotated source: embryonic/larval rectum
annotated property: definition
annotated target: Posterior-most portion of the embryonic/larval alimentary canal, terminating in the anus.
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0186027

embryonic/larval anus
type: Class
subclass of: FBbt_00047153
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval rectum
definition: Posterior opening of the embryonic/larval hindgut.
has exact synonym: larval anus
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001893
in subset: cur

Axiom
annotated source: embryonic/larval anus
annotated property: definition
annotated target: Posterior opening of the embryonic/larval hindgut.
database_cross_reference: FBC:SPR

embryonic/larval Malpighian tubule
type: Class
subclass of: Malpighian tubule
subclass of: Restriction
  on property: part of
  some values from: larval excretory system
subclass of: Restriction
  on property: continuous with
  some values from: embryonic/larval hindgut
subclass of: Restriction
  on property: develops from
  some values from: embryonic Malpighian tubule
definition: Malpighian tubule of the embryo/larva. The larval tubule is very similar to that of the adult, except that the initial segment of the anterior tubule is bigger in the larva.
has exact synonym: larval Malpighian tubule
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001896
in subset: cur

Axiom
annotated source: embryonic/larval Malpighian tubule
annotated property: definition
annotated target: Malpighian tubule of the embryo/larva. The larval tubule is very similar to that of the adult, except that the initial segment of the anterior tubule is bigger in the larva.
database_cross_reference: FlyBase:FBrf0222532

embryonic/larval Malpighian tubule segment
type: Class
equivalent class: Class
  intersection of: Malpighian tubule segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: Malpighian tubule segment
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval Malpighian tubule
subclass of: Restriction
  on property: develops from
  some values from: embryonic Malpighian tubule segment
definition: Malpighian tubule segment of the embryo/larva.
has exact synonym: larval Malpighian tubule segment
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001899
in subset: cur

Axiom
annotated source: embryonic/larval Malpighian tubule segment
annotated property: definition
annotated target: Malpighian tubule segment of the embryo/larva.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic/larval initial segment of Malpighian tubule
type: Class
equivalent class: Class
  intersection of: initial segment of Malpighian tubule
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: embryonic/larval Malpighian tubule segment
subclass of: initial segment of Malpighian tubule
subclass of: Restriction
  on property: develops from
  some values from: embryonic initial segment of Malpighian tubule
definition: Distal segment of the embryonic/larval Malpighian tubule. The initial segment of the larva is bigger than in the adult.
has exact synonym: larval initial segment of Malpighian tubule
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001900
in subset: cur

Axiom
annotated source: embryonic/larval initial segment of Malpighian tubule
annotated property: definition
annotated target: Distal segment of the embryonic/larval Malpighian tubule. The initial segment of the larva is bigger than in the adult.
database_cross_reference: FlyBase:FBrf0222532
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic/larval ureter
type: Class
equivalent class: Class
  intersection of: ureter
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: embryonic/larval Malpighian tubule segment
subclass of: ureter
subclass of: Restriction
  on property: develops from
  some values from: embryonic ureter
definition: Proximal segment connecting a pair of Malpighian tubules to the alimentary canal in the embryo/larva. The ureter is surrounded by longitudinal and circular muscles.
has exact synonym: larval ureter
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001903
in subset: cur

Axiom
annotated source: embryonic/larval ureter
annotated property: definition
annotated target: Proximal segment connecting a pair of Malpighian tubules to the alimentary canal in the embryo/larva. The ureter is surrounded by longitudinal and circular muscles.
database_cross_reference: FlyBase:FBrf0030988

embryonic/larval specialized Malpighian tubule cell
type: Class
equivalent class: Class
  intersection of: specialized Malpighian tubule cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: specialized Malpighian tubule cell
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval Malpighian tubule
definition: Specialized cell of the embryonic/larval Malpighian tubules.
has exact synonym: embryonic/larval specialised Malpighian tubule cell
has exact synonym: larval specialized Malpighian tubule cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001904
in subset: cur

Axiom
annotated source: embryonic/larval specialized Malpighian tubule cell
annotated property: definition
annotated target: Specialized cell of the embryonic/larval Malpighian tubules.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

larval Malpighian tubule tip cell
type: Class
equivalent class: Class
  intersection of: Malpighian tubule tip cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: embryonic/larval specialized Malpighian tubule cell
subclass of: Malpighian tubule tip cell
definition: Tip cell of the embryonic/larval Malpighian tubule.
has exact synonym: embryonic/larval Malpighian tubule tip cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001905
in subset: cur

Axiom
annotated source: larval Malpighian tubule tip cell
annotated property: definition
annotated target: Tip cell of the embryonic/larval Malpighian tubule.
database_cross_reference: FlyBase:FBrf0223292

embryonic/larval Malpighian tubule Type I cell
type: Class
equivalent class: Class
  intersection of: Malpighian tubule Type I cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: embryonic/larval specialized Malpighian tubule cell
subclass of: Malpighian tubule Type I cell
definition: Type I cell of the embryonic/larval Malpighian tubules.
has exact synonym: PC
has exact synonym: larval Malpighian tubule Type I cell
has exact synonym: larval Malpighian tubule principal cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001906
in subset: cur

Axiom
annotated source: embryonic/larval Malpighian tubule Type I cell
annotated property: definition
annotated target: Type I cell of the embryonic/larval Malpighian tubules.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

Axiom
annotated source: embryonic/larval Malpighian tubule Type I cell
annotated property: hasExactSynonym
annotated target: larval Malpighian tubule principal cell
database_cross_reference: FlyBase:FBrf0030988

larval nervous system
type: Class
equivalent class: Class
  intersection of: nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: nervous system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Nervous system of the embryo/larva.
has alternative id: FBbt:00005719
database_cross_reference: UBERON:6001911
database_cross_reference: VFB:FBbt_00001911
has exact synonym: embryonic/larval nervous system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001911
in subset: cur

Axiom
annotated source: larval nervous system
annotated property: definition
annotated target: Nervous system of the embryo/larva.
database_cross_reference: FlyBase:FBrf0045359
database_cross_reference: FlyBase:FBrf0075072
database_cross_reference: FlyBase:FBrf0105282

larval neuromere
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: neuromere
subclass of: Class
  intersection of: Restriction
    on property: part of
    some values from: larval segment
  intersection of: Restriction
    on property: part of
    some values from: larval central nervous system
definition: Neuromere of the larval nervous system.
database_cross_reference: VFB:FBbt_00001912
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001912
in subset: cur

Axiom
annotated source: larval neuromere
annotated property: definition
annotated target: Neuromere of the larval nervous system.
database_cross_reference: FlyBase:FBrf0047815
database_cross_reference: FlyBase:FBrf0084032
database_cross_reference: FlyBase:FBrf0089217
database_cross_reference: FlyBase:FBrf0105282

larval central nervous system
type: Class
equivalent class: Class
  intersection of: central nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: central nervous system
subclass of: Restriction
  on property: part of
  some values from: larval nervous system
definition: Central nervous system of the embryo/larva.
database_cross_reference: UBERON:6001919
database_cross_reference: VFB:FBbt_00001919
has exact synonym: embryonic/larval CNS
has exact synonym: embryonic/larval central nervous system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001919
in subset: cur
in subset: larval OF

Axiom
annotated source: larval central nervous system
annotated property: definition
annotated target: Central nervous system of the embryo/larva.
database_cross_reference: FBC:SPR

larval brain
type: Class
equivalent class: Class
  intersection of: brain
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: supraesophageal ganglion
subclass of: brain
subclass of: FBbt_00025991
subclass of: Class
  intersection of: Restriction
    on property: part of
    some values from: larval head
  intersection of: Restriction
    on property: part of
    some values from: larval central nervous system
subclass of: Restriction
  on property: develops from
  some values from: embryonic brain
definition: Supraesophageal ganglion of the late embryo or larva, consisting of the protocerebrum, deutocerebrum and tritocerebrum (Urbach and Technau, 2003; Li et al., 2014; Crews, 2019).
database_cross_reference: UBERON:6001920
database_cross_reference: VFB:FBbt_00001920
has exact synonym: embryonic/larval SPG
has exact synonym: embryonic/larval brain
has exact synonym: embryonic/larval supraesophageal complex
has exact synonym: embryonic/larval supraesophageal ganglion
has exact synonym: larval SPG
has exact synonym: larval cerebral ganglion
has exact synonym: larval supraesophageal ganglion
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001920
in subset: BrainName
in subset: cur
in subset: larval OF

Axiom
annotated source: larval brain
annotated property: definition
annotated target: Supraesophageal ganglion of the late embryo or larva, consisting of the protocerebrum, deutocerebrum and tritocerebrum (Urbach and Technau, 2003; Li et al., 2014; Crews, 2019).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0225812
database_cross_reference: FlyBase:FBrf0244240

Axiom
annotated source: larval brain
annotated property: hasExactSynonym
annotated target: embryonic/larval supraesophageal complex
database_cross_reference: FlyBase:FBrf0225812

embryonic/larval supraesophageal connective
type: Class
equivalent class: Class
  intersection of: connective
  intersection of: Restriction
    on property: part of
    some values from: larval brain
subclass of: connective
subclass of: Restriction
  on property: part of
  some values from: larval brain
definition: Connective of the embryonic/larval supraesophageal ganglion.
database_cross_reference: VFB:FBbt_00001921
has exact synonym: larval supraesophageal connective
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001921
in subset: cur

Axiom
annotated source: embryonic/larval supraesophageal connective
annotated property: definition
annotated target: Connective of the embryonic/larval supraesophageal ganglion.
database_cross_reference: FlyBase:FBrf0105282

larval protocerebrum
type: Class
equivalent class: Class
  intersection of: protocerebrum
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuromere
subclass of: protocerebrum
subclass of: Restriction
  on property: part of
  some values from: FBbt_00051070
subclass of: Restriction
  on property: overlaps
  some values from: larval ocular segment
subclass of: Restriction
  on property: overlaps
  some values from: larval labral segment
definition: Protocerebrum of the embryo/larva.
database_cross_reference: UBERON:6001925
database_cross_reference: VFB:FBbt_00001925
database_cross_reference: larvalbrain_neuropil:392
database_cross_reference: larvalbrain_neuropil:570
has exact synonym: embryonic/larval protocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001925
in subset: cur
in subset: larval OF

Axiom
annotated source: larval protocerebrum
annotated property: definition
annotated target: Protocerebrum of the embryo/larva.
database_cross_reference: FBC:SPR

embryonic/larval optic lobe
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: larval protocerebrum
definition: Region of the embryonic or larval brain that contains the neuroepithelial cells that will give rise to the adult optic lobe, and the larval optic neuropil that processes visual information in the larva.
database_cross_reference: VFB:FBbt_00001930
database_cross_reference: larvalbrain_neuropil:391
database_cross_reference: larvalbrain_neuropil:569
has exact synonym: larval optic lobe
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001930
in subset: cur

Axiom
annotated source: embryonic/larval optic lobe
annotated property: definition
annotated target: Region of the embryonic or larval brain that contains the neuroepithelial cells that will give rise to the adult optic lobe, and the larval optic neuropil that processes visual information in the larva.
database_cross_reference: FlyBase:FBrf0052913
database_cross_reference: FlyBase:FBrf0064800
database_cross_reference: FlyBase:FBrf0215208

larval outer optic anlage
type: Class
subclass of: FBbt_00007676
subclass of: Restriction
  on property: develops from
  some values from: embryonic outer optic lobe primordium
subclass of: Restriction
  on property: develops into
  some values from: lamina anlage
definition: The lateral, outer layer of the larval optic lobe. It consists of neuroepithelial cells (and later of proliferating neuroblasts) that will give rise to the neurons of the adult lamina and outer medulla. By the late first instar, it is dome shaped and perforated at its center by a pore, through which axons of the optic stalk pass (Meinertzhagen and Hanson, 1993). Some of these axons form synapses in the larval optic neuropil, which is largely within this pore (Sprecher et al., 2011). It becomes distinguished from the inner optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons. This anlage is patterned by expression of Optix and Vsx1 in complementary regions (Gold and Brand, 2014).
database_cross_reference: VFB:FBbt_00001933
has exact synonym: OOA
has exact synonym: embryonic/larval outer optic anlage
has narrow synonym: OPC
has narrow synonym: outer proliferation center
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001933
in subset: cur
comment: 'proliferation center' synonyms usually used for later stages of development (Ngo et al., 2017 - FBrf0236058).

Axiom
annotated source: larval outer optic anlage
annotated property: definition
annotated target: The lateral, outer layer of the larval optic lobe. It consists of neuroepithelial cells (and later of proliferating neuroblasts) that will give rise to the neurons of the adult lamina and outer medulla. By the late first instar, it is dome shaped and perforated at its center by a pore, through which axons of the optic stalk pass (Meinertzhagen and Hanson, 1993). Some of these axons form synapses in the larval optic neuropil, which is largely within this pore (Sprecher et al., 2011). It becomes distinguished from the inner optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons. This anlage is patterned by expression of Optix and Vsx1 in complementary regions (Gold and Brand, 2014).
database_cross_reference: FlyBase:FBrf0052913
database_cross_reference: FlyBase:FBrf0064800
database_cross_reference: FlyBase:FBrf0193624
database_cross_reference: FlyBase:FBrf0225842

Axiom
annotated source: larval outer optic anlage
annotated property: hasExactSynonym
annotated target: OOA
database_cross_reference: FlyBase:FBrf0204205

Axiom
annotated source: larval outer optic anlage
annotated property: hasNarrowSynonym
annotated target: OPC
database_cross_reference: FlyBase:FBrf0095642

Axiom
annotated source: larval outer optic anlage
annotated property: hasNarrowSynonym
annotated target: outer proliferation center
database_cross_reference: FlyBase:FBrf0095642

medulla anlage
type: Class
subclass of: anlage
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00007676
subclass of: Restriction
  on property: develops into
  some values from: medulla
definition: A(n) anlage that develops into some medulla. It develops from some larval optic anlage.
database_cross_reference: VFB:FBbt_00001935
database_cross_reference: larvalbrain_neuropil:338
database_cross_reference: larvalbrain_neuropil:402
database_cross_reference: larvalbrain_neuropil:516
database_cross_reference: larvalbrain_neuropil:580
has exact synonym: larval medulla
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001935
in subset: cur

Axiom
annotated source: medulla anlage
annotated property: definition
annotated target: A(n) anlage that develops into some medulla. It develops from some larval optic anlage.
database_cross_reference: FBC:Autogenerated

medulla forming neuroblast
type: Class
subclass of: FBbt_00052344
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007676
subclass of: Restriction
  on property: expresses
  some values from: FBgn0000137
subclass of: Restriction
  on property: expresses
  some values from: FBgn0010109
definition: A neuroblast that is the precursor of the medulla. The neuroblasts that give rise to the outer medulla neurons are located in the medial edge of the larval outer optic anlage, whereas the neuroblasts that give rise to the inner medulla neurons are located in the larval inner optic anlage.
database_cross_reference: VFB:FBbt_00001938
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001938
in subset: cur
comment: Can be distinguished from other optic lobe neuroblasts based on expression of dpn and ase (Konstantinides et al., 2022).

Axiom
annotated source: medulla forming neuroblast
annotated property: definition
annotated target: A neuroblast that is the precursor of the medulla. The neuroblasts that give rise to the outer medulla neurons are located in the medial edge of the larval outer optic anlage, whereas the neuroblasts that give rise to the inner medulla neurons are located in the larval inner optic anlage.
database_cross_reference: FlyBase:FBrf0193624
database_cross_reference: FlyBase:FBrf0214710
database_cross_reference: FlyBase:FBrf0253187

lamina anlage
type: Class
subclass of: anlage
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: larval outer optic anlage
subclass of: Restriction
  on property: develops into
  some values from: lamina
definition: A zone of proliferating neuroblasts that forms at mid third instar, at the lateral rim of the outer optic anlage. Descendants of these neuroblasts form the adult lamina.
has alternative id: FBbt:00001950
database_cross_reference: VFB:FBbt_00001939
database_cross_reference: larvalbrain_neuropil:376
database_cross_reference: larvalbrain_neuropil:554
has exact synonym: larval lamina
has exact synonym: lateral proliferation zone
has exact synonym: lpo
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001939
in subset: cur

Axiom
annotated source: lamina anlage
annotated property: definition
annotated target: A zone of proliferating neuroblasts that forms at mid third instar, at the lateral rim of the outer optic anlage. Descendants of these neuroblasts form the adult lamina.
database_cross_reference: FlyBase:FBrf0052913

Axiom
annotated source: lamina anlage
annotated property: hasExactSynonym
annotated target: lpo
database_cross_reference: FlyBase:FBrf0052913

lobula anlage
type: Class
subclass of: anlage
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: larval inner optic anlage
subclass of: Restriction
  on property: develops into
  some values from: lobula
definition: Anlage of the embryo/larva that is the precursor to the adult lobula.
database_cross_reference: VFB:FBbt_00001944
database_cross_reference: larvalbrain_neuropil:378
database_cross_reference: larvalbrain_neuropil:400
database_cross_reference: larvalbrain_neuropil:556
database_cross_reference: larvalbrain_neuropil:578
has exact synonym: larval lobula
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001944
in subset: cur

Axiom
annotated source: lobula anlage
annotated property: definition
annotated target: Anlage of the embryo/larva that is the precursor to the adult lobula.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

lobula plate anlage
type: Class
subclass of: anlage
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: larval inner optic anlage
subclass of: Restriction
  on property: develops into
  some values from: lobula plate
definition: A(n) anlage that develops into some lobula plate. It develops from some larval inner optic anlage.
database_cross_reference: VFB:FBbt_00001946
database_cross_reference: larvalbrain_neuropil:380
database_cross_reference: larvalbrain_neuropil:401
database_cross_reference: larvalbrain_neuropil:558
database_cross_reference: larvalbrain_neuropil:579
has exact synonym: larval lobula plate
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001946
in subset: cur

Axiom
annotated source: lobula plate anlage
annotated property: definition
annotated target: A(n) anlage that develops into some lobula plate. It develops from some larval inner optic anlage.
database_cross_reference: FBC:Autogenerated

cell body rind of adult lobula plate
type: Class
subclass of: FBbt_00100200
subclass of: Restriction
  on property: part of
  some values from: FBbt_00111152
subclass of: Restriction
  on property: continuous with
  some values from: lobula plate
definition: Region of the adult brain cell body rind that overlies the lobula plate.
database_cross_reference: VFB:FBbt_00001948
has exact synonym: cortex of lobula plate
has exact synonym: lobula plate cortex
has exact synonym: rLOP
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001948
in subset: cur

Axiom
annotated source: cell body rind of adult lobula plate
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the lobula plate.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult lobula plate
annotated property: hasExactSynonym
annotated target: rLOP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

larval inner optic anlage
type: Class
subclass of: FBbt_00007676
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: lobula anlage
  intersection of: Restriction
    on property: develops into
    some values from: lobula plate anlage
subclass of: Restriction
  on property: develops from
  some values from: embryonic inner optic lobe primordium
definition: A ribbon-like layer of neuroepithelial cells (and later of proliferating neuroblasts) in the larval optic lobe that gives rise to the adult inner medulla, lobula and lobula plate neurons. In early larval stages it is composed of neuroepithelial cells that divide symmetrically. In the early second instar it becomes U shaped, with the opening of the U pointing in a dorso-caudal direction. It becomes distinguished from the outer optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons.
database_cross_reference: VFB:FBbt_00001951
has exact synonym: IOA
has exact synonym: embryonic/larval inner optic anlage
has narrow synonym: IPC
has narrow synonym: inner proliferation center
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001951
in subset: cur
comment: 'proliferation center' synonyms usually used for later stages of development (Ngo et al., 2017 - FBrf0236058).

Axiom
annotated source: larval inner optic anlage
annotated property: definition
annotated target: A ribbon-like layer of neuroepithelial cells (and later of proliferating neuroblasts) in the larval optic lobe that gives rise to the adult inner medulla, lobula and lobula plate neurons. In early larval stages it is composed of neuroepithelial cells that divide symmetrically. In the early second instar it becomes U shaped, with the opening of the U pointing in a dorso-caudal direction. It becomes distinguished from the outer optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons.
database_cross_reference: FlyBase:FBrf0052913
database_cross_reference: FlyBase:FBrf0193624

Axiom
annotated source: larval inner optic anlage
annotated property: hasExactSynonym
annotated target: IOA
database_cross_reference: FlyBase:FBrf0204205

Axiom
annotated source: larval inner optic anlage
annotated property: hasNarrowSynonym
annotated target: IPC
database_cross_reference: FlyBase:FBrf0095642

Axiom
annotated source: larval inner optic anlage
annotated property: hasNarrowSynonym
annotated target: inner proliferation center
database_cross_reference: FlyBase:FBrf0095642

larval deutocerebrum
type: Class
equivalent class: Class
  intersection of: larval neuromere
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: larval neuromere
subclass of: deutocerebrum
subclass of: Restriction
  on property: part of
  some values from: larval antennal segment
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047889
subclass of: Restriction
  on property: part of
  some values from: FBbt_00051070
definition: Deutocerebrum of the embryo/larva.
database_cross_reference: VFB:FBbt_00001957
database_cross_reference: larvalbrain_neuropil:337
database_cross_reference: larvalbrain_neuropil:515
has exact synonym: embryonic/larval deuterocerebrum
has exact synonym: embryonic/larval deutocerebrum
has exact synonym: larval deuterocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001957
in subset: cur
in subset: larval OF

Axiom
annotated source: larval deutocerebrum
annotated property: definition
annotated target: Deutocerebrum of the embryo/larva.
database_cross_reference: FBC:SPR

larval tritocerebrum
type: Class
equivalent class: Class
  intersection of: larval neuromere
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: larval neuromere
subclass of: tritocerebrum
subclass of: Restriction
  on property: part of
  some values from: larval intercalary segment
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval periesophageal neuropils
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047889
subclass of: Restriction
  on property: overlaps
  some values from: FBbt_00051067
subclass of: Restriction
  on property: overlaps
  some values from: FBbt_00051070
definition: Tritocerebrum of the late embryonic or larval brain. It is found at the base of the brain hemispheres, partially below the esophagus (Hartenstein et al., 2015; Hartenstein et al., 2018).
database_cross_reference: VFB:FBbt_00001962
database_cross_reference: larvalbrain_neuropil:418
database_cross_reference: larvalbrain_neuropil:596
has exact synonym: embryonic/larval tritocerebrum
has exact synonym: larval PENPa
has exact synonym: larval anterior periesophageal neuropils
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001962
in subset: cur

Axiom
annotated source: larval tritocerebrum
annotated property: definition
annotated target: Tritocerebrum of the late embryonic or larval brain. It is found at the base of the brain hemispheres, partially below the esophagus (Hartenstein et al., 2015; Hartenstein et al., 2018).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0229672
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: larval tritocerebrum
annotated property: hasExactSynonym
annotated target: larval PENPa
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: larval tritocerebrum
annotated property: hasExactSynonym
annotated target: larval anterior periesophageal neuropils
database_cross_reference: FlyBase:FBrf0229672

supraesophageal nerve
type: Class
equivalent class: Class
  intersection of: nerve
  intersection of: Restriction
    on property: innervates
    some values from: supraesophageal ganglion
subclass of: nerve
subclass of: Restriction
  on property: innervates
  some values from: supraesophageal ganglion
definition: Nerve that innervates the supraesophageal ganglion.
database_cross_reference: VFB:FBbt_00001964
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001964
in subset: cur
in subset: larval OF

Axiom
annotated source: supraesophageal nerve
annotated property: definition
annotated target: Nerve that innervates the supraesophageal ganglion.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

subesophageal zone neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: FBbt_00051068
subclass of: FBbt_00059271
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00051068
definition: Any neuron (FBbt:00005106) that has its soma located in some subesophageal zone (FBbt:00051068).
database_cross_reference: VFB:FBbt_00001972
has exact synonym: SEZ neuron
has OBO namespace: fly_anatomy.ontology
has related synonym: SEG neuron
has related synonym: SOG neuron
has related synonym: subesophageal ganglion neuron
id: FBbt:00001972
in subset: cur

Axiom
annotated source: subesophageal zone neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some subesophageal zone (FBbt:00051068).
database_cross_reference: FBC:Autogenerated

larval mandibular neuromere
type: Class
equivalent class: Class
  intersection of: larval neuromere
  intersection of: Restriction
    on property: part of
    some values from: mandibular segment
subclass of: FBbt_00111045
subclass of: Restriction
  on property: part of
  some values from: larval mandibular segment
definition: Any larval neuromere (FBbt:00001912) that is part of some mandibular segment (FBbt:00000012).
has broad synonym: mandibula
database_cross_reference: VFB:FBbt_00001973
database_cross_reference: larvalbrain_neuropil:386
database_cross_reference: larvalbrain_neuropil:564
has exact synonym: larval S1 neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001973
in subset: cur

Axiom
annotated source: larval mandibular neuromere
annotated property: definition
annotated target: Any larval neuromere (FBbt:00001912) that is part of some mandibular segment (FBbt:00000012).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: larval mandibular neuromere
annotated property: hasExactSynonym
annotated target: larval S1 neuromere
database_cross_reference: FlyBase:FBrf0210278

larval labial neuromere
type: Class
equivalent class: Class
  intersection of: larval neuromere
  intersection of: Restriction
    on property: part of
    some values from: labial segment
subclass of: FBbt_00111045
subclass of: Restriction
  on property: part of
  some values from: larval labial segment
definition: Any larval neuromere (FBbt:00001912) that is part of some labial segment (FBbt:00000014).
has broad synonym: labium
database_cross_reference: VFB:FBbt_00001974
database_cross_reference: larvalbrain_neuropil:377
database_cross_reference: larvalbrain_neuropil:555
has exact synonym: larval S3 neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001974
in subset: cur

Axiom
annotated source: larval labial neuromere
annotated property: definition
annotated target: Any larval neuromere (FBbt:00001912) that is part of some labial segment (FBbt:00000014).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: larval labial neuromere
annotated property: hasExactSynonym
annotated target: larval S3 neuromere
database_cross_reference: FlyBase:FBrf0210278

larval maxillary neuromere
type: Class
equivalent class: Class
  intersection of: larval neuromere
  intersection of: Restriction
    on property: part of
    some values from: maxillary segment
subclass of: FBbt_00111045
subclass of: Restriction
  on property: part of
  some values from: larval maxillary segment
definition: Any larval neuromere (FBbt:00001912) that is part of some maxillary segment (FBbt:00000013).
has broad synonym: maxilla
database_cross_reference: VFB:FBbt_00001975
database_cross_reference: larvalbrain_neuropil:390
database_cross_reference: larvalbrain_neuropil:568
has exact synonym: larval S2 neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001975
in subset: cur

Axiom
annotated source: larval maxillary neuromere
annotated property: definition
annotated target: Any larval neuromere (FBbt:00001912) that is part of some maxillary segment (FBbt:00000013).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: larval maxillary neuromere
annotated property: hasExactSynonym
annotated target: larval S2 neuromere
database_cross_reference: FlyBase:FBrf0210278

subesophageal nerve
type: Class
equivalent class: Class
  intersection of: nerve
  intersection of: Restriction
    on property: innervates
    some values from: gnathal ganglion
subclass of: nerve
subclass of: Restriction
  on property: innervates
  some values from: gnathal ganglion
definition: Nerve that innervates the subesophageal ganglion.
database_cross_reference: VFB:FBbt_00001976
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001976
in subset: cur

Axiom
annotated source: subesophageal nerve
annotated property: definition
annotated target: Nerve that innervates the subesophageal ganglion.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

thoracic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: thoracic segment
subclass of: neuron
subclass of: Restriction
  on property: has soma location
  some values from: thoracic segment
definition: Any neuron (FBbt:00005106) that has its soma located in some thoracic segment (FBbt:00000016).
database_cross_reference: VFB:FBbt_00001983
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001983
in subset: cur

Axiom
annotated source: thoracic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some thoracic segment (FBbt:00000016).
database_cross_reference: FBC:Autogenerated

prothoracic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: prothoracic segment
subclass of: thoracic neuron
subclass of: Restriction
  on property: has soma location
  some values from: prothoracic segment
definition: Any neuron (FBbt:00005106) that has its soma located in some prothoracic segment (FBbt:00000017).
database_cross_reference: VFB:FBbt_00001984
has exact synonym: thoracic T1 neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001984
in subset: cur

Axiom
annotated source: prothoracic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

mesothoracic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: mesothoracic segment
subclass of: thoracic neuron
subclass of: Restriction
  on property: has soma location
  some values from: mesothoracic segment
definition: Any neuron (FBbt:00005106) that has its soma located in some mesothoracic segment (FBbt:00000018).
database_cross_reference: VFB:FBbt_00001985
has exact synonym: thoracic T2 neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001985
in subset: cur

Axiom
annotated source: mesothoracic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some mesothoracic segment (FBbt:00000018).
database_cross_reference: FBC:Autogenerated

metathoracic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: metathoracic segment
subclass of: thoracic neuron
subclass of: Restriction
  on property: has soma location
  some values from: metathoracic segment
definition: Any neuron (FBbt:00005106) that has its soma located in some metathoracic segment (FBbt:00000019).
database_cross_reference: VFB:FBbt_00001986
has exact synonym: thoracic T3 neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001986
in subset: cur

Axiom
annotated source: metathoracic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some metathoracic segment (FBbt:00000019).
database_cross_reference: FBC:Autogenerated

abdominal neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: abdomen
subclass of: neuron
subclass of: Restriction
  on property: has soma location
  some values from: abdomen
definition: Any neuron (FBbt:00005106) that has its soma located in some abdomen (FBbt:00000020).
database_cross_reference: VFB:FBbt_00001987
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001987
in subset: cur

Axiom
annotated source: abdominal neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some abdomen (FBbt:00000020).
database_cross_reference: FBC:Autogenerated

larval abdominal 6 neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: larval abdominal segment 6
subclass of: larval neuron
subclass of: abdominal neuron
subclass of: Restriction
  on property: has soma location
  some values from: larval abdominal segment 6
definition: Any neuron (FBbt:00005106) that has its soma located in some larval abdominal segment 6 (FBbt:00001753).
database_cross_reference: VFB:FBbt_00001993
has exact synonym: larval A6 neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001993
in subset: cur

Axiom
annotated source: larval abdominal 6 neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some larval abdominal segment 6 (FBbt:00001753).
database_cross_reference: FBC:Autogenerated

larval abdominal 8 neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: larval abdominal segment 8
subclass of: larval neuron
subclass of: abdominal neuron
subclass of: Restriction
  on property: has soma location
  some values from: larval abdominal segment 8
definition: Any neuron (FBbt:00005106) that has its soma located in some larval abdominal segment 8 (FBbt:00001755).
database_cross_reference: VFB:FBbt_00001995
has exact synonym: larval A8 neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001995
in subset: cur

Axiom
annotated source: larval abdominal 8 neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some larval abdominal segment 8 (FBbt:00001755).
database_cross_reference: FBC:Autogenerated

larval segmental nerve
type: Class
subclass of: nerve
subclass of: Restriction
  on property: part of
  some values from: larval peripheral nervous system
definition: Larval nerve found in segments T1-A7 that has two roots, both carrying fibers from the neuromere of the nerve (Campos-Ortega and Hartenstein, 1997). It exits the lateral ventral nerve cord in line with the anterior commissure and its proximal region shares a glial sheath with the intersegmental nerve (Campos-Ortega and Hartenstein, 1997). It does not extend as far dorsally as the intersegmental nerve, and mainly innervates ventral muscles and sense organs (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: VFB:FBbt_00002037
has exact synonym: larval SN
has OBO namespace: fly_anatomy.ontology
has related synonym: posterior fascicle
id: FBbt:00002037
in subset: cur

Axiom
annotated source: larval segmental nerve
annotated property: definition
annotated target: Larval nerve found in segments T1-A7 that has two roots, both carrying fibers from the neuromere of the nerve (Campos-Ortega and Hartenstein, 1997). It exits the lateral ventral nerve cord in line with the anterior commissure and its proximal region shares a glial sheath with the intersegmental nerve (Campos-Ortega and Hartenstein, 1997). It does not extend as far dorsally as the intersegmental nerve, and mainly innervates ventral muscles and sense organs (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

larval segmental nerve sensory neuron
type: Class
equivalent class: Class
  intersection of: sensory neuron
  intersection of: Restriction
    on property: fasciculates with
    some values from: larval segmental nerve
subclass of: FBbt_00058245
subclass of: FBbt_00059275
subclass of: Restriction
  on property: part of
  some values from: larval peripheral nervous system
subclass of: Restriction
  on property: fasciculates with
  some values from: larval segmental nerve
definition: Larval sensory neuron that fasciculates with a segmental nerve. In abdominal segments 1-7, these are the sensory neurons located in the ventral and ventral' clusters (Campos-Ortega and Hartenstein, 1997; Singhania and Grueber, 2014).
database_cross_reference: VFB:FBbt_00002038
has exact synonym: posterior fascicle sensory neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002038
in subset: cur

Axiom
annotated source: larval segmental nerve sensory neuron
annotated property: definition
annotated target: Larval sensory neuron that fasciculates with a segmental nerve. In abdominal segments 1-7, these are the sensory neurons located in the ventral and ventral' clusters (Campos-Ortega and Hartenstein, 1997; Singhania and Grueber, 2014).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0225306

Axiom
annotated source: larval segmental nerve sensory neuron
annotated property: hasExactSynonym
annotated target: posterior fascicle sensory neuron
database_cross_reference: FlyBase:FBrf0089570

larval ventral cluster group multidendritic neuron
type: Class
equivalent class: Class
  intersection of: multidendritic neuron
  intersection of: Restriction
    on property: has soma location
    some values from: FBbt_00007295
subclass of: FBbt_00048285
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00007295
definition: Any multidendritic neuron (FBbt:00005209) that has its soma located in some larval ventral sensory cluster group (FBbt:00007295).
database_cross_reference: VFB:FBbt_00002054
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002054
in subset: cur

Axiom
annotated source: larval ventral cluster group multidendritic neuron
annotated property: definition
annotated target: Any multidendritic neuron (FBbt:00005209) that has its soma located in some larval ventral sensory cluster group (FBbt:00007295).
database_cross_reference: FBC:Autogenerated

prothoracic nerve
type: Class
equivalent class: Class
  intersection of: nerve
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: nerve
subclass of: Restriction
  on property: part of
  some values from: prothoracic segment
definition: Any nerve (FBbt:00005105) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: VFB:FBbt_00002063
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002063
in subset: cur

Axiom
annotated source: prothoracic nerve
annotated property: definition
annotated target: Any nerve (FBbt:00005105) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

larval prothoracic multidendritic neuron
type: Class
equivalent class: Class
  intersection of: FBbt_00048285
  intersection of: Restriction
    on property: has soma location
    some values from: larval prothoracic segment
subclass of: prothoracic neuron
subclass of: FBbt_00048285
subclass of: Restriction
  on property: has soma location
  some values from: larval prothoracic segment
definition: Multidendritic neuron of the dorsal or lateral sensory clusters in the embryonic/larval prothoracic segment. It fasciculates with the intersegmental nerve.
database_cross_reference: VFB:FBbt_00002075
has narrow synonym: larval prothoracic dorsal/lateral/ventral multidendritic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002075
in subset: cur

Axiom
annotated source: larval prothoracic multidendritic neuron
annotated property: definition
annotated target: Multidendritic neuron of the dorsal or lateral sensory clusters in the embryonic/larval prothoracic segment. It fasciculates with the intersegmental nerve.
database_cross_reference: FlyBase:FBrf0089570

larval prothoracic segmental nerve
type: Class
equivalent class: Class
  intersection of: larval segmental nerve
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: larval segmental nerve
subclass of: prothoracic nerve
subclass of: Restriction
  on property: part of
  some values from: larval prothoracic segment
definition: Larval segmental nerve of the prothoracic segment. Similar to the A1-A7 nerves, it has two roots, anterior and posterior, both formed from neurons of the same segment as the nerve (Campos-Ortega and Hartenstein, 1997). Proximally it shares a glial sheath with the intersegmental nerve before branching from it at the border between the prothorax and mesothorax (Campos-Ortega and Hartenstein, 1997). It receives sensory fibers from the ventral monoscolopidial chordotonal organ, Keilin organ and vc1 sensillum (Campos-Ortega and Hartenstein, 1997). It gives off a thick branch to the ventral intersegmental muscle, while its main branch continues to the ventral transverse musculature, the ventral Kolbchen and the vc2 sensillum (Campos-Ortega and Hartenstein, 1997).
has broad synonym: SN
database_cross_reference: VFB:FBbt_00002085
has exact synonym: prothoracic posterior fascicle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002085
in subset: cur

Axiom
annotated source: larval prothoracic segmental nerve
annotated property: definition
annotated target: Larval segmental nerve of the prothoracic segment. Similar to the A1-A7 nerves, it has two roots, anterior and posterior, both formed from neurons of the same segment as the nerve (Campos-Ortega and Hartenstein, 1997). Proximally it shares a glial sheath with the intersegmental nerve before branching from it at the border between the prothorax and mesothorax (Campos-Ortega and Hartenstein, 1997). It receives sensory fibers from the ventral monoscolopidial chordotonal organ, Keilin organ and vc1 sensillum (Campos-Ortega and Hartenstein, 1997). It gives off a thick branch to the ventral intersegmental muscle, while its main branch continues to the ventral transverse musculature, the ventral Kolbchen and the vc2 sensillum (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

prothoracic posterior fascicle neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: fasciculates with
    some values from: larval prothoracic segmental nerve
subclass of: larval neuron
subclass of: Restriction
  on property: fasciculates with
  some values from: larval prothoracic segmental nerve
definition: Any neuron (FBbt:00005106) that fasciculates with some larval prothoracic segmental nerve (FBbt:00002085).
database_cross_reference: VFB:FBbt_00002086
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002086
in subset: cur

Axiom
annotated source: prothoracic posterior fascicle neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that fasciculates with some larval prothoracic segmental nerve (FBbt:00002085).
database_cross_reference: FBC:Autogenerated

prothoracic ventral' multidendritic neuron
type: Class
equivalent class: Class
  intersection of: larval ventral cluster group multidendritic neuron
  intersection of: Restriction
    on property: has soma location
    some values from: larval prothoracic segment
subclass of: larval segmental nerve sensory neuron
subclass of: larval ventral cluster group multidendritic neuron
subclass of: larval prothoracic multidendritic neuron
subclass of: prothoracic posterior fascicle neuron
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00052124
subclass of: Restriction
  on property: develops from
  some values from: ventral group thoracic dendritic arborizing neuron precursor cell
definition: Larval multidendritic neuron of the ventral' sensory cluster of the prothoracic segment (Campos-Ortega and Hartenstein, 1997). There are four of these on each side, all of which have axons that fasciculate with the prothoracic segmental nerve (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: VFB:FBbt_00002098
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002098
in subset: cur
in subset: hidden assertion
comment: There are no multidendritic neurons in the ventral cluster in thoracic segments.

Axiom
annotated source: prothoracic ventral' multidendritic neuron
annotated property: definition
annotated target: Larval multidendritic neuron of the ventral' sensory cluster of the prothoracic segment (Campos-Ortega and Hartenstein, 1997). There are four of these on each side, all of which have axons that fasciculate with the prothoracic segmental nerve (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

mesothoracic nerve
type: Class
equivalent class: Class
  intersection of: nerve
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: nerve
subclass of: Restriction
  on property: part of
  some values from: mesothoracic segment
definition: Any nerve (FBbt:00005105) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: VFB:FBbt_00002103
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002103
in subset: cur

Axiom
annotated source: mesothoracic nerve
annotated property: definition
annotated target: Any nerve (FBbt:00005105) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: FBC:Autogenerated

larval mesothoracic multidendritic neuron
type: Class
equivalent class: Class
  intersection of: FBbt_00048285
  intersection of: Restriction
    on property: has soma location
    some values from: larval mesothoracic segment
subclass of: mesothoracic neuron
subclass of: FBbt_00048285
subclass of: Restriction
  on property: has soma location
  some values from: larval mesothoracic segment
definition: Multidendritic neuron of the dorsal or lateral sensory clusters in the embryonic/larval mesothoracic segment. It fasciculates with the intersegmental nerve.
database_cross_reference: VFB:FBbt_00002115
has narrow synonym: larval mesothoracic dorsal/lateral/ventral multidendritic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002115
in subset: cur

Axiom
annotated source: larval mesothoracic multidendritic neuron
annotated property: definition
annotated target: Multidendritic neuron of the dorsal or lateral sensory clusters in the embryonic/larval mesothoracic segment. It fasciculates with the intersegmental nerve.
database_cross_reference: FlyBase:FBrf0089570

larval mesothoracic segmental nerve
type: Class
equivalent class: Class
  intersection of: larval segmental nerve
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: larval segmental nerve
subclass of: mesothoracic nerve
subclass of: Restriction
  on property: part of
  some values from: larval mesothoracic segment
definition: Larval segmental nerve of the mesothoracic segment. Similar to the A1-A7 nerves, it has two roots, anterior and posterior, both formed from neurons of the same segment as the nerve (Campos-Ortega and Hartenstein, 1997). Proximally it shares a glial sheath with the intersegmental nerve (Campos-Ortega and Hartenstein, 1997). It receives sensory fibers from the ventral monoscolopidial chordotonal organ, Keilin organ and vc1 sensillum (Campos-Ortega and Hartenstein, 1997). It gives off a thick branch to the ventral lateral muscle, while its main branch continues to the lateral transverse musculature, the ventral Kolbchen and the vc2 sensillum (Campos-Ortega and Hartenstein, 1997). It additionally receives sensory fibers from the prothoracic lch3 chordotonal organ (Campos-Ortega and Hartenstein, 1997).
has broad synonym: SN
database_cross_reference: VFB:FBbt_00002125
has exact synonym: mesothoracic posterior fascicle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002125
in subset: cur

Axiom
annotated source: larval mesothoracic segmental nerve
annotated property: definition
annotated target: Larval segmental nerve of the mesothoracic segment. Similar to the A1-A7 nerves, it has two roots, anterior and posterior, both formed from neurons of the same segment as the nerve (Campos-Ortega and Hartenstein, 1997). Proximally it shares a glial sheath with the intersegmental nerve (Campos-Ortega and Hartenstein, 1997). It receives sensory fibers from the ventral monoscolopidial chordotonal organ, Keilin organ and vc1 sensillum (Campos-Ortega and Hartenstein, 1997). It gives off a thick branch to the ventral lateral muscle, while its main branch continues to the lateral transverse musculature, the ventral Kolbchen and the vc2 sensillum (Campos-Ortega and Hartenstein, 1997). It additionally receives sensory fibers from the prothoracic lch3 chordotonal organ (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

mesothoracic posterior fascicle neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: fasciculates with
    some values from: larval mesothoracic segmental nerve
subclass of: larval neuron
subclass of: Restriction
  on property: fasciculates with
  some values from: larval mesothoracic segmental nerve
definition: Any neuron (FBbt:00005106) that fasciculates with some larval mesothoracic segmental nerve (FBbt:00002125).
database_cross_reference: VFB:FBbt_00002126
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002126
in subset: cur

Axiom
annotated source: mesothoracic posterior fascicle neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that fasciculates with some larval mesothoracic segmental nerve (FBbt:00002125).
database_cross_reference: FBC:Autogenerated

mesothoracic ventral' multidendritic neuron
type: Class
equivalent class: Class
  intersection of: larval ventral cluster group multidendritic neuron
  intersection of: Restriction
    on property: has soma location
    some values from: larval mesothoracic segment
subclass of: larval segmental nerve sensory neuron
subclass of: larval ventral cluster group multidendritic neuron
subclass of: larval mesothoracic multidendritic neuron
subclass of: mesothoracic posterior fascicle neuron
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00052125
subclass of: Restriction
  on property: develops from
  some values from: ventral group thoracic dendritic arborizing neuron precursor cell
definition: Larval multidendritic neuron of the ventral' sensory cluster of the mesothoracic segment (Campos-Ortega and Hartenstein, 1997). There are four of these on each side, all of which have axons that fasciculate with the mesothoracic segmental nerve (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: VFB:FBbt_00002136
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002136
in subset: cur
in subset: hidden assertion
comment: There are no multidendritic neurons in the ventral cluster in thoracic segments.

Axiom
annotated source: mesothoracic ventral' multidendritic neuron
annotated property: definition
annotated target: Larval multidendritic neuron of the ventral' sensory cluster of the mesothoracic segment (Campos-Ortega and Hartenstein, 1997). There are four of these on each side, all of which have axons that fasciculate with the mesothoracic segmental nerve (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

metathoracic nerve
type: Class
equivalent class: Class
  intersection of: nerve
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: nerve
subclass of: Restriction
  on property: part of
  some values from: metathoracic segment
definition: Any nerve (FBbt:00005105) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: VFB:FBbt_00002141
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002141
in subset: cur

Axiom
annotated source: metathoracic nerve
annotated property: definition
annotated target: Any nerve (FBbt:00005105) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: FBC:Autogenerated

larval metathoracic multidendritic neuron
type: Class
equivalent class: Class
  intersection of: FBbt_00048285
  intersection of: Restriction
    on property: has soma location
    some values from: larval metathoracic segment
subclass of: metathoracic neuron
subclass of: FBbt_00048285
subclass of: Restriction
  on property: has soma location
  some values from: larval metathoracic segment
definition: Multidendritic neuron of the dorsal or lateral sensory clusters in the embryonic/larval metathoracic segment. It fasciculates with the intersegmental nerve.
database_cross_reference: VFB:FBbt_00002153
has narrow synonym: larval metathoracic dorsal/lateral/ventral multidendritic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002153
in subset: cur

Axiom
annotated source: larval metathoracic multidendritic neuron
annotated property: definition
annotated target: Multidendritic neuron of the dorsal or lateral sensory clusters in the embryonic/larval metathoracic segment. It fasciculates with the intersegmental nerve.
database_cross_reference: FlyBase:FBrf0089570

larval metathoracic segmental nerve
type: Class
equivalent class: Class
  intersection of: larval segmental nerve
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: larval segmental nerve
subclass of: metathoracic nerve
subclass of: Restriction
  on property: part of
  some values from: larval metathoracic segment
definition: Larval segmental nerve of the metathoracic segment. Similar to the A1-A7 nerves, it has two roots, anterior and posterior, both formed from neurons of the same segment as the nerve (Campos-Ortega and Hartenstein, 1997). Proximally it shares a glial sheath with the intersegmental nerve (Campos-Ortega and Hartenstein, 1997). It receives sensory fibers from the ventral monoscolopidial chordotonal organ, Keilin organ and vc1 sensillum (Campos-Ortega and Hartenstein, 1997). It gives off a thick branch to the ventral lateral muscle, while its main branch continues to the lateral transverse musculature, the ventral Kolbchen and the vc2 sensillum (Campos-Ortega and Hartenstein, 1997).
has broad synonym: SN
database_cross_reference: VFB:FBbt_00002163
has exact synonym: metathoracic posterior fascicle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002163
in subset: cur

Axiom
annotated source: larval metathoracic segmental nerve
annotated property: definition
annotated target: Larval segmental nerve of the metathoracic segment. Similar to the A1-A7 nerves, it has two roots, anterior and posterior, both formed from neurons of the same segment as the nerve (Campos-Ortega and Hartenstein, 1997). Proximally it shares a glial sheath with the intersegmental nerve (Campos-Ortega and Hartenstein, 1997). It receives sensory fibers from the ventral monoscolopidial chordotonal organ, Keilin organ and vc1 sensillum (Campos-Ortega and Hartenstein, 1997). It gives off a thick branch to the ventral lateral muscle, while its main branch continues to the lateral transverse musculature, the ventral Kolbchen and the vc2 sensillum (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

metathoracic posterior fascicle neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: fasciculates with
    some values from: larval metathoracic segmental nerve
subclass of: larval neuron
subclass of: Restriction
  on property: fasciculates with
  some values from: larval metathoracic segmental nerve
definition: Any neuron (FBbt:00005106) that fasciculates with some larval metathoracic segmental nerve (FBbt:00002163).
database_cross_reference: VFB:FBbt_00002164
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002164
in subset: cur

Axiom
annotated source: metathoracic posterior fascicle neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that fasciculates with some larval metathoracic segmental nerve (FBbt:00002163).
database_cross_reference: FBC:Autogenerated

metathoracic ventral' multidendritic neuron
type: Class
equivalent class: Class
  intersection of: larval ventral cluster group multidendritic neuron
  intersection of: Restriction
    on property: has soma location
    some values from: larval metathoracic segment
subclass of: larval segmental nerve sensory neuron
subclass of: larval ventral cluster group multidendritic neuron
subclass of: larval metathoracic multidendritic neuron
subclass of: metathoracic posterior fascicle neuron
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00052126
subclass of: Restriction
  on property: develops from
  some values from: ventral group thoracic dendritic arborizing neuron precursor cell
definition: Larval multidendritic neuron of the ventral' sensory cluster of the metathoracic segment (Campos-Ortega and Hartenstein, 1997). There are four of these on each side, all of which have axons that fasciculate with the metathoracic segmental nerve (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: VFB:FBbt_00002174
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002174
in subset: cur
in subset: hidden assertion
comment: There are no multidendritic neurons in the ventral cluster in thoracic segments.

Axiom
annotated source: metathoracic ventral' multidendritic neuron
annotated property: definition
annotated target: Larval multidendritic neuron of the ventral' sensory cluster of the metathoracic segment (Campos-Ortega and Hartenstein, 1997). There are four of these on each side, all of which have axons that fasciculate with the metathoracic segmental nerve (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

abdominal nerve
type: Class
equivalent class: Class
  intersection of: nerve
  intersection of: Restriction
    on property: part of
    some values from: abdomen
subclass of: nerve
subclass of: Restriction
  on property: part of
  some values from: abdomen
definition: Any nerve (FBbt:00005105) that is part of some abdomen (FBbt:00000020).
database_cross_reference: VFB:FBbt_00002179
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002179
in subset: cur

Axiom
annotated source: abdominal nerve
annotated property: definition
annotated target: Any nerve (FBbt:00005105) that is part of some abdomen (FBbt:00000020).
database_cross_reference: FlyBase:FBrf0054490

larval abdominal segmental nerve
type: Class
equivalent class: Class
  intersection of: larval segmental nerve
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment
subclass of: larval segmental nerve
subclass of: FBbt_00047362
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007586
definition: Larval segmental nerve of a larval abdominal segment. These are only found in segments A1-7, as A8 and A9 do not have separate segmental and intersegmental nerves (Campos-Ortega and Hartenstein, 1997). It has two roots, anterior and posterior, both formed from neurons of the same segment as the nerve (Campos-Ortega and Hartenstein, 1997). Proximally it shares a glial sheath with the intersegmental nerve before branching from it at the ventral edge of the ventral oblique muscles (Campos-Ortega and Hartenstein, 1997). A thick, posteriorly directed branch (SNc) leaves the main trunk of the nerve (SNa) and splits into fine branches - 3 carrying axons from the ventral sensory cluster and a 4th carrying efferents to the ventral acute musculature (Campos-Ortega and Hartenstein, 1997). The SNa branch continues dorsally and carries efferent axons innervating the external lateral transverse and lateral oblique muscles and the axons of v'es2 and v'ch1 (Campos-Ortega and Hartenstein, 1997).
has alternative id: FBbt:00002450
database_cross_reference: VFB:FBbt_00002197
has exact synonym: larval abdominal SN
has exact synonym: larval abdominal posterior fascicle
has exact synonym: larval segmental nerve of A1-7
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002197
in subset: cur

Axiom
annotated source: larval abdominal segmental nerve
annotated property: definition
annotated target: Larval segmental nerve of a larval abdominal segment. These are only found in segments A1-7, as A8 and A9 do not have separate segmental and intersegmental nerves (Campos-Ortega and Hartenstein, 1997). It has two roots, anterior and posterior, both formed from neurons of the same segment as the nerve (Campos-Ortega and Hartenstein, 1997). Proximally it shares a glial sheath with the intersegmental nerve before branching from it at the ventral edge of the ventral oblique muscles (Campos-Ortega and Hartenstein, 1997). A thick, posteriorly directed branch (SNc) leaves the main trunk of the nerve (SNa) and splits into fine branches - 3 carrying axons from the ventral sensory cluster and a 4th carrying efferents to the ventral acute musculature (Campos-Ortega and Hartenstein, 1997). The SNa branch continues dorsally and carries efferent axons innervating the external lateral transverse and lateral oblique muscles and the axons of v'es2 and v'ch1 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0099344

Axiom
annotated source: larval abdominal segmental nerve
annotated property: hasExactSynonym
annotated target: larval abdominal posterior fascicle
database_cross_reference: FlyBase:FBrf0089570

larval abdominal multidendritic neuron
type: Class
equivalent class: Class
  intersection of: FBbt_00048285
  intersection of: Restriction
    on property: has soma location
    some values from: larval abdominal segment
subclass of: FBbt_00048285
subclass of: FBbt_00100296
subclass of: Restriction
  on property: has soma location
  some values from: larval abdominal segment
definition: Any larval multidendritic neuron (FBbt:00048285) that has its soma located in some larval abdominal segment (FBbt:00001747).
database_cross_reference: VFB:FBbt_00002385
has narrow synonym: larval abdominal dorsal/lateral/ventral multidendritic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002385
in subset: cur

Axiom
annotated source: larval abdominal multidendritic neuron
annotated property: definition
annotated target: Any larval multidendritic neuron (FBbt:00048285) that has its soma located in some larval abdominal segment (FBbt:00001747).
database_cross_reference: FlyBase:FBrf0089570

larval abdominal segmental nerve neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: fasciculates with
    some values from: larval abdominal segmental nerve
subclass of: larval neuron
subclass of: Restriction
  on property: fasciculates with
  some values from: larval abdominal segmental nerve
definition: Any neuron (FBbt:00005106) that fasciculates with some larval abdominal segmental nerve (FBbt:00002197).
database_cross_reference: VFB:FBbt_00002451
has exact synonym: abdominal posterior fascicle neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002451
in subset: cur

Axiom
annotated source: larval abdominal segmental nerve neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that fasciculates with some larval abdominal segmental nerve (FBbt:00002197).
database_cross_reference: FBC:Autogenerated

larval abdominal ventral cluster group multidendritic neuron
type: Class
equivalent class: Class
  intersection of: larval ventral cluster group multidendritic neuron
  intersection of: Restriction
    on property: has soma location
    some values from: larval abdominal segment
subclass of: larval segmental nerve sensory neuron
subclass of: larval ventral cluster group multidendritic neuron
subclass of: larval abdominal multidendritic neuron
subclass of: larval abdominal segmental nerve neuron
subclass of: FBbt_00047944
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00007309
subclass of: Restriction
  on property: develops from
  some values from: ventral group abdominal dendritic arborizing neuron precursor cell
definition: Any larval ventral cluster group multidendritic neuron (FBbt:00002054) that has its soma located in some larval abdominal segment (FBbt:00001747).
database_cross_reference: VFB:FBbt_00002516
has OBO namespace: fly_anatomy.ontology
has related synonym: abdominal ventral multidendritic neuron
id: FBbt:00002516
in subset: cur

Axiom
annotated source: larval abdominal ventral cluster group multidendritic neuron
annotated property: definition
annotated target: Any larval ventral cluster group multidendritic neuron (FBbt:00002054) that has its soma located in some larval abdominal segment (FBbt:00001747).
database_cross_reference: FlyBase:FBrf0045359

abdominal 8 sensory neuron
type: Class
equivalent class: Class
  intersection of: sensory neuron
  intersection of: Restriction
    on property: has soma location
    some values from: larval abdominal segment 8
subclass of: larval abdominal 8 neuron
subclass of: FBbt_00058245
subclass of: FBbt_00100296
definition: Any sensory neuron (FBbt:00005124) that has its soma located in some larval abdominal segment 8 (FBbt:00001755).
database_cross_reference: VFB:FBbt_00002607
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002607
in subset: cur

Axiom
annotated source: abdominal 8 sensory neuron
annotated property: definition
annotated target: Any sensory neuron (FBbt:00005124) that has its soma located in some larval abdominal segment 8 (FBbt:00001755).
database_cross_reference: FBC:Autogenerated

larval abdominal 9 nerve
type: Class
subclass of: FBbt_00047362
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 9
subclass of: Restriction
  on property: continuous with
  some values from: FBbt_00052537
definition: Nerve of larval abdominal segment 9 that has features of both the intersegmental and segmental nerves of more anterior segments (Campos-Ortega and Hartenstein, 1997). It has two roots and its proximal section is closely attached to the abdominal 8 nerve (Campos-Ortega and Hartenstein, 1997). After passing beneath the gut suspensor muscles, it gives off a thick recurrent branch, the hindgut nerve, which innervates the hindgut (Campos-Ortega and Hartenstein, 1997). Its main branch continues dorsoposteriorly and gives off a motor branch that innervates the A9 terminal oblique muscles (Campos-Ortega and Hartenstein, 1997). A posterior branch carries sensory axons from the anal sense organ and a dorsal branch carries axons of motor and sensory neurons of A9 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: VFB:FBbt_00002618
has exact synonym: nerve of a9
has OBO namespace: fly_anatomy.ontology
has related synonym: larval abdominal 9 intersegmental nerve
id: FBbt:00002618
in subset: cur

Axiom
annotated source: larval abdominal 9 nerve
annotated property: definition
annotated target: Nerve of larval abdominal segment 9 that has features of both the intersegmental and segmental nerves of more anterior segments (Campos-Ortega and Hartenstein, 1997). It has two roots and its proximal section is closely attached to the abdominal 8 nerve (Campos-Ortega and Hartenstein, 1997). After passing beneath the gut suspensor muscles, it gives off a thick recurrent branch, the hindgut nerve, which innervates the hindgut (Campos-Ortega and Hartenstein, 1997). Its main branch continues dorsoposteriorly and gives off a motor branch that innervates the A9 terminal oblique muscles (Campos-Ortega and Hartenstein, 1997). A posterior branch carries sensory axons from the anal sense organ and a dorsal branch carries axons of motor and sensory neurons of A9 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: larval abdominal 9 nerve
annotated property: hasExactSynonym
annotated target: nerve of a9
database_cross_reference: FlyBase:FBrf0089570

abdominal 9 sensory neuron
type: Class
equivalent class: Class
  intersection of: sensory neuron
  intersection of: Restriction
    on property: has soma location
    some values from: larval abdominal segment 9
subclass of: FBbt_00047944
subclass of: FBbt_00100296
subclass of: Restriction
  on property: has soma location
  some values from: larval abdominal segment 9
subclass of: Restriction
  on property: fasciculates with
  some values from: larval abdominal 9 nerve
definition: Any sensory neuron (FBbt:00005124) that has its soma located in some larval abdominal segment 9 (FBbt:00001756).
database_cross_reference: VFB:FBbt_00002619
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002619
in subset: cur

Axiom
annotated source: abdominal 9 sensory neuron
annotated property: definition
annotated target: Any sensory neuron (FBbt:00005124) that has its soma located in some larval abdominal segment 9 (FBbt:00001756).
database_cross_reference: FBC:Autogenerated

abdominal 9 multidendritic neuron
type: Class
equivalent class: Class
  intersection of: FBbt_00048285
  intersection of: Restriction
    on property: has soma location
    some values from: larval abdominal segment 9
subclass of: larval abdominal multidendritic neuron
subclass of: abdominal 9 sensory neuron
definition: Multidendritic neuron of the ventral region of larval abdominal segment 9. There are several of these neurons.
database_cross_reference: VFB:FBbt_00002622
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002622
in subset: cur

Axiom
annotated source: abdominal 9 multidendritic neuron
annotated property: definition
annotated target: Multidendritic neuron of the ventral region of larval abdominal segment 9. There are several of these neurons.
database_cross_reference: FlyBase:FBrf0089570

larval sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Any sense organ of the larva.
database_cross_reference: UBERON:6002639
database_cross_reference: VFB:FBbt_00002639
has exact synonym: embryonic/larval sense organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002639
in subset: cur

Axiom
annotated source: larval sense organ
annotated property: definition
annotated target: Any sense organ of the larva.
database_cross_reference: FBC:Autogenerated

larval ocular segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: ocular segment
subclass of: FBbt_00007280
subclass of: Restriction
  on property: part of
  some values from: larval ocular segment
definition: Any larval sense organ (FBbt:00002639) that is part of some ocular segment (FBbt:00000005).
database_cross_reference: UBERON:6002642
database_cross_reference: VFB:FBbt_00002642
has narrow synonym: embryonic/larval ocular segment sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002642
in subset: cur

Axiom
annotated source: larval ocular segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some ocular segment (FBbt:00000005).
database_cross_reference: FBC:Autogenerated

embryonic/larval labral segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: labral segment
subclass of: FBbt_00007280
subclass of: Restriction
  on property: part of
  some values from: larval labral segment
definition: Any larval sense organ (FBbt:00002639) that is part of some labral segment (FBbt:00000008).
has alternative id: FBbt:00002650
database_cross_reference: VFB:FBbt_00002649
has exact synonym: larval labral segment sense organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002649
in subset: cur

Axiom
annotated source: embryonic/larval labral segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some labral segment (FBbt:00000008).
database_cross_reference: FBC:Autogenerated

larval antennal segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: antennal sense organ
subclass of: FBbt_00007280
subclass of: Restriction
  on property: part of
  some values from: larval antennal segment
definition: Any larval sense organ (FBbt:00002639) that is part of some antennal segment (FBbt:00000009).
database_cross_reference: VFB:FBbt_00002654
has narrow synonym: embryonic/larval antennal segment sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002654
in subset: cur

Axiom
annotated source: larval antennal segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some antennal segment (FBbt:00000009).
database_cross_reference: FBC:Autogenerated

intercalary segment sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: intercalary segment
definition: Any sense organ (FBbt:00005155) that is part of some intercalary segment (FBbt:00000010).
database_cross_reference: VFB:FBbt_00002664
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002664
in subset: cur

Axiom
annotated source: intercalary segment sense organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is part of some intercalary segment (FBbt:00000010).
database_cross_reference: FBC:Autogenerated

larval mandibular segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: mandibular segment
subclass of: FBbt_00007280
subclass of: Restriction
  on property: part of
  some values from: larval mandibular segment
definition: Any larval sense organ (FBbt:00002639) that is part of some mandibular segment (FBbt:00000012).
database_cross_reference: VFB:FBbt_00002685
has narrow synonym: larval mandibular segment sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002685
in subset: cur

Axiom
annotated source: larval mandibular segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some mandibular segment (FBbt:00000012).
database_cross_reference: FBC:Autogenerated

larval maxillary segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: maxillary segment
subclass of: dorsal ectoderm derivative
subclass of: FBbt_00007280
subclass of: Restriction
  on property: part of
  some values from: larval maxillary segment
subclass of: Restriction
  on property: develops from
  some values from: embryonic maxillary sensory complex
definition: Any larval sense organ (FBbt:00002639) that is part of some maxillary segment (FBbt:00000013).
database_cross_reference: VFB:FBbt_00002689
has OBO namespace: fly_anatomy.ontology
has related synonym: larval maxillary segment organ
id: FBbt:00002689
in subset: cur
in subset: hidden assertion

Axiom
annotated source: larval maxillary segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some maxillary segment (FBbt:00000013).
database_cross_reference: FBC:Autogenerated

embryonic/larval labial segment sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007240
  intersection of: Restriction
    on property: part of
    some values from: labial segment
subclass of: labial sensillum
subclass of: FBbt_00007242
subclass of: Restriction
  on property: part of
  some values from: larval labial segment
definition: Any larval sensillum (FBbt:00007240) that is part of some labial segment (FBbt:00000014).
has exact synonym: larval labial segment sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002718
in subset: cur

Axiom
annotated source: embryonic/larval labial segment sensillum
annotated property: definition
annotated target: Any larval sensillum (FBbt:00007240) that is part of some labial segment (FBbt:00000014).
database_cross_reference: FBC:Autogenerated

labial sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: labial segment
subclass of: head sensillum
subclass of: Restriction
  on property: part of
  some values from: labial segment
definition: Any sensillum (FBbt:00007152) that is part of some labial segment (FBbt:00000014).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002721
in subset: cur

Axiom
annotated source: labial sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some labial segment (FBbt:00000014).
database_cross_reference: FBC:Autogenerated

embryonic/larval prothoracic sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007240
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: FBbt_00007244
subclass of: Restriction
  on property: part of
  some values from: larval prothoracic segment
definition: Any larval sensillum (FBbt:00007240) that is part of some prothoracic segment (FBbt:00000017).
has exact synonym: larval prothoracic sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002725
in subset: cur

Axiom
annotated source: embryonic/larval prothoracic sensillum
annotated property: definition
annotated target: Any larval sensillum (FBbt:00007240) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

larval mesothoracic sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007240
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: FBbt_00007244
subclass of: Restriction
  on property: part of
  some values from: larval mesothoracic segment
definition: Any larval sensillum (FBbt:00007240) that is part of some mesothoracic segment (FBbt:00000018).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002746
in subset: cur

Axiom
annotated source: larval mesothoracic sensillum
annotated property: definition
annotated target: Any larval sensillum (FBbt:00007240) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: FBC:Autogenerated

mesothoracic Keilin organ
type: Class
equivalent class: Class
  intersection of: Keilin organ
  intersection of: Restriction
    on property: part of
    some values from: larval mesothoracic segment
subclass of: larval mesothoracic sensillum
subclass of: Keilin organ
subclass of: Restriction
  on property: part of
  some values from: FBbt_00052119
definition: Any Keilin organ (FBbt:00005198) that is part of some larval mesothoracic segment (FBbt:00001744).
has broad synonym: sh A
database_cross_reference: VFB:FBbt_00002761
has exact synonym: mesothoracic Keilin's organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002761
in subset: cur

Axiom
annotated source: mesothoracic Keilin organ
annotated property: definition
annotated target: Any Keilin organ (FBbt:00005198) that is part of some larval mesothoracic segment (FBbt:00001744).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: mesothoracic Keilin organ
annotated property: hasBroadSynonym
annotated target: sh A
database_cross_reference: FlyBase:FBrf0034076

larval metathoracic sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007240
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: FBbt_00007244
subclass of: Restriction
  on property: part of
  some values from: larval metathoracic segment
definition: Any larval sensillum (FBbt:00007240) that is part of some metathoracic segment (FBbt:00000019).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002764
in subset: cur

Axiom
annotated source: larval metathoracic sensillum
annotated property: definition
annotated target: Any larval sensillum (FBbt:00007240) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: FBC:Autogenerated

metathoracic Keilin organ
type: Class
equivalent class: Class
  intersection of: Keilin organ
  intersection of: Restriction
    on property: part of
    some values from: larval metathoracic segment
subclass of: larval metathoracic sensillum
subclass of: Keilin organ
subclass of: Restriction
  on property: part of
  some values from: FBbt_00052120
definition: Any Keilin organ (FBbt:00005198) that is part of some larval metathoracic segment (FBbt:00001745).
has broad synonym: sh A
database_cross_reference: VFB:FBbt_00002779
has exact synonym: metathoracic Keilin's organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002779
in subset: cur

Axiom
annotated source: metathoracic Keilin organ
annotated property: definition
annotated target: Any Keilin organ (FBbt:00005198) that is part of some larval metathoracic segment (FBbt:00001745).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: metathoracic Keilin organ
annotated property: hasBroadSynonym
annotated target: sh A
database_cross_reference: FlyBase:FBrf0034076

larval abdominal sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: larval abdomen
subclass of: FBbt_00007240
subclass of: Restriction
  on property: part of
  some values from: larval abdomen
definition: Any sensillum (FBbt:00007152) that is part of some larval abdomen (FBbt:00001746).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002782
in subset: cur

Axiom
annotated source: larval abdominal sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some larval abdomen (FBbt:00001746).
database_cross_reference: FBC:Autogenerated

embryonic/larval abdominal 8 sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007240
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 8
subclass of: larval abdominal sensillum
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 8
definition: Any larval sensillum (FBbt:00007240) that is part of some abdominal segment 8 (FBbt:00000029).
has exact synonym: larval abdominal 8 sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002928
in subset: cur

Axiom
annotated source: embryonic/larval abdominal 8 sensillum
annotated property: definition
annotated target: Any larval sensillum (FBbt:00007240) that is part of some abdominal segment 8 (FBbt:00000029).
database_cross_reference: FBC:Autogenerated

embryonic/larval abdominal 9 sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007240
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 9
subclass of: larval abdominal sensillum
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 9
definition: Any larval sensillum (FBbt:00007240) that is part of some abdominal segment 9 (FBbt:00000030).
has exact synonym: larval abdominal 9 sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002942
in subset: cur

Axiom
annotated source: embryonic/larval abdominal 9 sensillum
annotated property: definition
annotated target: Any larval sensillum (FBbt:00007240) that is part of some abdominal segment 9 (FBbt:00000030).
database_cross_reference: FBC:Autogenerated

embryonic/larval abdominal 11 sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007240
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 11
subclass of: larval abdominal sensillum
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 11
definition: Any larval sensillum (FBbt:00007240) that is part of some abdominal segment 11 (FBbt:00000032).
has exact synonym: larval abdominal 11 sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002950
in subset: cur

Axiom
annotated source: embryonic/larval abdominal 11 sensillum
annotated property: definition
annotated target: Any larval sensillum (FBbt:00007240) that is part of some abdominal segment 11 (FBbt:00000032).
database_cross_reference: FBC:Autogenerated

prepupa
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: larva
definition: The prepupa is the name given to the organism at the period of the life cycle that begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C is approximately 12 hours. It occurs 120-132.2 hours after egg laying, and is the period of 0-12.2 hours after puparium formation.
database_cross_reference: UBERON:0003142
has OBO namespace: fly_anatomy.ontology
has related synonym: PP
id: FBbt:00002952
in subset: FB gloss
in subset: cur

Axiom
annotated source: prepupa
annotated property: definition
annotated target: The prepupa is the name given to the organism at the period of the life cycle that begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C is approximately 12 hours. It occurs 120-132.2 hours after egg laying, and is the period of 0-12.2 hours after puparium formation.
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

pupa
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: prepupa
definition: The pupa is the name given to the organism at the period of the life cycle that begins once larval/pupal apolysis is complete, as indicated by the expulsion of the larval armature. Early in this stage the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. The duration of this stage is approximately 32 hours at 25 degrees C, and spans from 132.2-164.3 hours after egg laying, or is the period of 12.2-44.3 hours after puparium formation.
database_cross_reference: UBERON:0003143
has OBO namespace: fly_anatomy.ontology
has related synonym: P
id: FBbt:00002953
in subset: FB gloss
in subset: cur

Axiom
annotated source: pupa
annotated property: definition
annotated target: The pupa is the name given to the organism at the period of the life cycle that begins once larval/pupal apolysis is complete, as indicated by the expulsion of the larval armature. Early in this stage the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. The duration of this stage is approximately 32 hours at 25 degrees C, and spans from 132.2-164.3 hours after egg laying, or is the period of 12.2-44.3 hours after puparium formation.
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

adult
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: pharate adult
definition: Organism at any stage after completing eclosion.
database_cross_reference: UBERON:0007023
has OBO namespace: fly_anatomy.ontology
has related synonym: imago
id: FBbt:00003004
in subset: FB gloss
in subset: cur

Axiom
annotated source: adult
annotated property: definition
annotated target: Organism at any stage after completing eclosion.
database_cross_reference: FlyBase:FBrf0036849

adult tagma
type: Class
equivalent class: Class
  intersection of: tagma
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: tagma
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Any tagma of the adult.
database_cross_reference: UBERON:6003005
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003005
in subset: cur

Axiom
annotated source: adult tagma
annotated property: definition
annotated target: Any tagma of the adult.
database_cross_reference: FBC:Autogenerated

adult segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Segment of the adult.
database_cross_reference: UBERON:6003006
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003006
in subset: cur

Axiom
annotated source: adult segment
annotated property: definition
annotated target: Segment of the adult.
database_cross_reference: FBC:SPR

adult head
type: Class
equivalent class: Class
  intersection of: head
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: head
subclass of: adult tagma
definition: Head of the adult organism.
database_cross_reference: UBERON:6003007
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003007
in subset: cur

Axiom
annotated source: adult head
annotated property: definition
annotated target: Head of the adult organism.
database_cross_reference: FBC:SPR

adult ocular segment
type: Class
equivalent class: Class
  intersection of: ocular segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: ocular segment
subclass of: adult procephalic segment
definition: Any ocular segment of the adult.
has OBO namespace: fly_anatomy.ontology
has related synonym: adult acron
id: FBbt:00003008
in subset: cur

Axiom
annotated source: adult ocular segment
annotated property: definition
annotated target: Any ocular segment of the adult.
database_cross_reference: FBC:Autogenerated

adult head segment
type: Class
equivalent class: Class
  intersection of: head segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: head segment
subclass of: adult segment
subclass of: Restriction
  on property: part of
  some values from: adult head
definition: Segment of the adult head.
database_cross_reference: UBERON:6003009
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003009
in subset: cur

Axiom
annotated source: adult head segment
annotated property: definition
annotated target: Segment of the adult head.
database_cross_reference: FlyBase:FBrf0064788

adult procephalic segment
type: Class
equivalent class: Class
  intersection of: procephalic segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: procephalic segment
subclass of: adult head segment
definition: Any procephalic segment of the adult.
database_cross_reference: UBERON:6003010
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003010
in subset: cur

Axiom
annotated source: adult procephalic segment
annotated property: definition
annotated target: Any procephalic segment of the adult.
database_cross_reference: FBC:Autogenerated

adult labral segment
type: Class
equivalent class: Class
  intersection of: labral segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: labral segment
subclass of: adult procephalic segment
definition: Any labral segment of the adult.
database_cross_reference: UBERON:6003011
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003011
in subset: cur

Axiom
annotated source: adult labral segment
annotated property: definition
annotated target: Any labral segment of the adult.
database_cross_reference: FBC:Autogenerated

adult antennal segment
type: Class
equivalent class: Class
  intersection of: antennal segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: antennal segment
subclass of: adult procephalic segment
definition: Any antennal segment of the adult.
has alternative id: FBbt:00004512
database_cross_reference: UBERON:6003012
has exact synonym: adult antennal structure
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003012
in subset: cur

Axiom
annotated source: adult antennal segment
annotated property: definition
annotated target: Any antennal segment of the adult.
database_cross_reference: FBC:Autogenerated

adult intercalary segment
type: Class
equivalent class: Class
  intersection of: intercalary segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: intercalary segment
subclass of: adult procephalic segment
definition: Any intercalary segment of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003013
in subset: cur

Axiom
annotated source: adult intercalary segment
annotated property: definition
annotated target: Any intercalary segment of the adult.
database_cross_reference: FBC:Autogenerated

adult gnathal segment
type: Class
equivalent class: Class
  intersection of: gnathal segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: gnathal segment
subclass of: adult head segment
definition: Any gnathal segment of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003014
in subset: cur

Axiom
annotated source: adult gnathal segment
annotated property: definition
annotated target: Any gnathal segment of the adult.
database_cross_reference: FBC:Autogenerated

adult mandibular segment
type: Class
equivalent class: Class
  intersection of: mandibular segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: mandibular segment
subclass of: adult gnathal segment
definition: Any mandibular segment of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003015
in subset: cur

Axiom
annotated source: adult mandibular segment
annotated property: definition
annotated target: Any mandibular segment of the adult.
database_cross_reference: FBC:Autogenerated

adult maxillary segment
type: Class
equivalent class: Class
  intersection of: maxillary segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: maxillary segment
subclass of: adult gnathal segment
definition: Any maxillary segment of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003016
in subset: cur

Axiom
annotated source: adult maxillary segment
annotated property: definition
annotated target: Any maxillary segment of the adult.
database_cross_reference: FBC:Autogenerated

adult labial segment
type: Class
equivalent class: Class
  intersection of: labial segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: labial segment
subclass of: adult gnathal segment
definition: Any labial segment of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003017
in subset: cur

Axiom
annotated source: adult labial segment
annotated property: definition
annotated target: Any labial segment of the adult.
database_cross_reference: FBC:Autogenerated

adult thorax
type: Class
equivalent class: Class
  intersection of: thorax
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: thorax
subclass of: adult tagma
subclass of: Restriction
  on property: part of
  some values from: FBbt_00059181
definition: Thorax of the adult.
database_cross_reference: UBERON:6003018
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003018
in subset: cur

Axiom
annotated source: adult thorax
annotated property: definition
annotated target: Thorax of the adult.
database_cross_reference: FlyBase:FBim0000792

adult thoracic segment
type: Class
equivalent class: Class
  intersection of: thoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: thoracic segment
subclass of: adult segment
subclass of: Restriction
  on property: part of
  some values from: adult thorax
definition: Any thoracic segment of the adult.
database_cross_reference: UBERON:6003019
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003019
in subset: cur

Axiom
annotated source: adult thoracic segment
annotated property: definition
annotated target: Any thoracic segment of the adult.
database_cross_reference: FBC:Autogenerated

adult prothoracic segment
type: Class
equivalent class: Class
  intersection of: prothoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: prothoracic segment
subclass of: adult thoracic segment
definition: Any prothoracic segment of the adult.
database_cross_reference: UBERON:6003020
has exact synonym: prothorax
has exact synonym: t1
has exact synonym: thoracic segment 1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003020
in subset: cur

Axiom
annotated source: adult prothoracic segment
annotated property: definition
annotated target: Any prothoracic segment of the adult.
database_cross_reference: FBC:Autogenerated

adult mesothoracic segment
type: Class
equivalent class: Class
  intersection of: mesothoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: mesothoracic segment
subclass of: adult thoracic segment
definition: Any mesothoracic segment of the adult.
database_cross_reference: UBERON:6003021
has exact synonym: mesothorax
has exact synonym: t2
has exact synonym: thoracic segment 2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003021
in subset: cur

Axiom
annotated source: adult mesothoracic segment
annotated property: definition
annotated target: Any mesothoracic segment of the adult.
database_cross_reference: FBC:Autogenerated

adult metathoracic segment
type: Class
equivalent class: Class
  intersection of: metathoracic segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: metathoracic segment
subclass of: adult thoracic segment
definition: Any metathoracic segment of the adult.
has exact synonym: metathorax
has exact synonym: t3
has exact synonym: thoracic segment 3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003022
in subset: cur

Axiom
annotated source: adult metathoracic segment
annotated property: definition
annotated target: Any metathoracic segment of the adult.
database_cross_reference: FBC:Autogenerated

adult abdomen
type: Class
equivalent class: Class
  intersection of: abdomen
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: abdomen
subclass of: adult tagma
subclass of: Restriction
  on property: part of
  some values from: FBbt_00059181
definition: Abdomen of the adult.
database_cross_reference: UBERON:6003023
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003023
in subset: cur

Axiom
annotated source: adult abdomen
annotated property: definition
annotated target: Abdomen of the adult.
database_cross_reference: FlyBase:FBim0000809
database_cross_reference: FlyBase:FBim0000810

adult abdominal segment
type: Class
equivalent class: Class
  intersection of: abdominal segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: abdominal segment
subclass of: adult segment
subclass of: Restriction
  on property: part of
  some values from: adult abdomen
definition: Any abdominal segment of the adult.
database_cross_reference: UBERON:6003024
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003024
in subset: cur

Axiom
annotated source: adult abdominal segment
annotated property: definition
annotated target: Any abdominal segment of the adult.
database_cross_reference: FBC:Autogenerated

adult abdominal segment 6
type: Class
equivalent class: Class
  intersection of: abdominal segment 6
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: abdominal segment 6
subclass of: FBbt_00052395
definition: Any abdominal segment 6 of the adult.
has OBO namespace: fly_anatomy.ontology
has related synonym: a6
id: FBbt:00003030
in subset: cur

Axiom
annotated source: adult abdominal segment 6
annotated property: definition
annotated target: Any abdominal segment 6 of the adult.
database_cross_reference: FBC:Autogenerated

adult abdominal segment 8
type: Class
equivalent class: Class
  intersection of: abdominal segment 8
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: abdominal segment 8
subclass of: FBbt_00052391
subclass of: Restriction
  on property: overlaps
  some values from: adult telson
definition: Any abdominal segment 8 of the adult.
has OBO namespace: fly_anatomy.ontology
has related synonym: a8
id: FBbt:00003032
in subset: cur

Axiom
annotated source: adult abdominal segment 8
annotated property: definition
annotated target: Any abdominal segment 8 of the adult.
database_cross_reference: FBC:Autogenerated

adult abdominal segment 9
type: Class
equivalent class: Class
  intersection of: abdominal segment 9
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: abdominal segment 9
subclass of: FBbt_00052391
subclass of: Restriction
  on property: part of
  some values from: adult telson
definition: Any abdominal segment 9 of the adult.
has OBO namespace: fly_anatomy.ontology
has related synonym: a9
id: FBbt:00003033
in subset: cur

Axiom
annotated source: adult abdominal segment 9
annotated property: definition
annotated target: Any abdominal segment 9 of the adult.
database_cross_reference: FBC:Autogenerated

adult abdominal segment 11
type: Class
equivalent class: Class
  intersection of: abdominal segment 11
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: abdominal segment 11
subclass of: FBbt_00052391
subclass of: Restriction
  on property: part of
  some values from: adult telson
definition: Any abdominal segment 11 of the adult.
has OBO namespace: fly_anatomy.ontology
has related synonym: a11
id: FBbt:00003035
in subset: cur

Axiom
annotated source: adult abdominal segment 11
annotated property: definition
annotated target: Any abdominal segment 11 of the adult.
database_cross_reference: FBC:Autogenerated

adult telson
type: Class
equivalent class: Class
  intersection of: telson
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: telson
subclass of: Restriction
  on property: part of
  some values from: adult abdomen
definition: Any telson of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003036
in subset: cur

Axiom
annotated source: adult telson
annotated property: definition
annotated target: Any telson of the adult.
database_cross_reference: FBC:Autogenerated

adult tracheal system
type: Class
equivalent class: Class
  intersection of: tracheal system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: tracheal system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Tracheal system of the adult. It retains the same basic pattern of the larval tracheal system, except for the presence of air sacs and the disappearance of the last tracheal segment. It is composed of nine tracheal metameres.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003037
in subset: cur

Axiom
annotated source: adult tracheal system
annotated property: definition
annotated target: Tracheal system of the adult. It retains the same basic pattern of the larval tracheal system, except for the presence of air sacs and the disappearance of the last tracheal segment. It is composed of nine tracheal metameres.
database_cross_reference: FlyBase:FBim0000051
database_cross_reference: FlyBase:FBim0000052
database_cross_reference: FlyBase:FBim0000053
database_cross_reference: FlyBase:FBrf0034081
database_cross_reference: FlyBase:FBrf0064787

adult digestive system
type: Class
equivalent class: Class
  intersection of: digestive system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: digestive system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Digestive system of the adult, comprising the alimentary canal, mouthparts, labellar glands, salivary glands and Malpighian tubules (Miller, 1950). The adult alimentary canal and salivary glands arise anew from precursors during metamorphosis (Bodenstein, 1950). The adult Malpighian tubules are remodelled from those of the larva (Bodenstein, 1950).
has OBO namespace: fly_anatomy.ontology
has related synonym: pupal/adult digestive system
id: FBbt:00003123
in subset: cur

Axiom
annotated source: adult digestive system
annotated property: definition
annotated target: Digestive system of the adult, comprising the alimentary canal, mouthparts, labellar glands, salivary glands and Malpighian tubules (Miller, 1950). The adult alimentary canal and salivary glands arise anew from precursors during metamorphosis (Bodenstein, 1950). The adult Malpighian tubules are remodelled from those of the larva (Bodenstein, 1950).
database_cross_reference: FlyBase:FBrf0007733
database_cross_reference: FlyBase:FBrf0007735

alimentary canal
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: digestive system
definition: The entire anatomical structure through which food and its digestion products are ingested, digested and excreted. At its anterior and posterior ends this includes structures that are not foregut or hindgut.
database_cross_reference: UBERON:0001555
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003125
in subset: cur

Axiom
annotated source: alimentary canal
annotated property: definition
annotated target: The entire anatomical structure through which food and its digestion products are ingested, digested and excreted. At its anterior and posterior ends this includes structures that are not foregut or hindgut.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult foregut
type: Class
subclass of: foregut
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007513
subclass of: Restriction
  on property: develops from
  some values from: foregut imaginal ring
definition: Anterior-most region of the adult alimentary canal. It consists (from anterior to posterior) of the posterior the pharynx (cibarium), esophagus, the crop, the stomodeal valve and part of the proventriculus.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003127
in subset: cur

Axiom
annotated source: adult foregut
annotated property: definition
annotated target: Anterior-most region of the adult alimentary canal. It consists (from anterior to posterior) of the posterior the pharynx (cibarium), esophagus, the crop, the stomodeal valve and part of the proventriculus.
database_cross_reference: FlyBase:FBrf0007735

crop
type: Class
subclass of: FBbt_00100316
subclass of: Restriction
  on property: part of
  some values from: adult foregut
definition: Pedunculate sac evaginating from the adult foregut just before it meets the midgut. It is a bi-lobed structure capable of considerable extension, whose function is the storage of ingested liquid food.
has exact synonym: pedunculate crop
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003133
in subset: cur

Axiom
annotated source: crop
annotated property: definition
annotated target: Pedunculate sac evaginating from the adult foregut just before it meets the midgut. It is a bi-lobed structure capable of considerable extension, whose function is the storage of ingested liquid food.
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0075527

Axiom
annotated source: crop
annotated property: hasExactSynonym
annotated target: pedunculate crop
database_cross_reference: FlyBase:FBrf0007735

adult salivary gland
type: Class
subclass of: salivary gland
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult digestive system
subclass of: Restriction
  on property: develops from
  some values from: salivary gland imaginal ring
definition: The salivary gland of the adult. It consists of two slender long, unbranched epithelial tubes of secretory epithelium that taper to form narrow ducts at their anterior end, which join to an unpaired duct (FBbt:00003137) in the neck region. The common duct connects to the salivary canal which runs through the hypopharynx and opens at its tip into the labial groove. The posterior ends of the lobes of the gland extend straight through the thorax on either side of the ventriculus and end in compact blind coils in the base of the abdomen. A suspensory muscle (FBbt:00003542) is attached to the anterior end of each lobe, near the cardia. (Miller, 1950 pg 440-1, 451).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003135
in subset: cur

Axiom
annotated source: adult salivary gland
annotated property: definition
annotated target: The salivary gland of the adult. It consists of two slender long, unbranched epithelial tubes of secretory epithelium that taper to form narrow ducts at their anterior end, which join to an unpaired duct (FBbt:00003137) in the neck region. The common duct connects to the salivary canal which runs through the hypopharynx and opens at its tip into the labial groove. The posterior ends of the lobes of the gland extend straight through the thorax on either side of the ventriculus and end in compact blind coils in the base of the abdomen. A suspensory muscle (FBbt:00003542) is attached to the anterior end of each lobe, near the cardia. (Miller, 1950 pg 440-1, 451).
database_cross_reference: FlyBase:FBrf0007735

adult midgut
type: Class
subclass of: midgut
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007513
subclass of: Restriction
  on property: develops from
  some values from: midgut imaginal island
definition: The middle region of the adult alimentary canal, the epithelium of which is lined with peritrophic membrane rather than chitinous intima as for the foregut and hindgut. The radius along the midgut is not uniform, with 6 major constrictions delimiting 6 regions (R0-R5). The anterior midgut (R1-R2) functions in absorption, the posterior (R4-R5) plays a role in reabsorption, and the middle acidic region (R3), which contains the copper cells (adult cuprophilic cell), in secretion and absorption.
has alternative id: FBbt:00003141
has exact synonym: adult ventriculus
has OBO namespace: fly_anatomy.ontology
has related synonym: mesenteron
id: FBbt:00003138
in subset: cur

Axiom
annotated source: adult midgut
annotated property: definition
annotated target: The middle region of the adult alimentary canal, the epithelium of which is lined with peritrophic membrane rather than chitinous intima as for the foregut and hindgut. The radius along the midgut is not uniform, with 6 major constrictions delimiting 6 regions (R0-R5). The anterior midgut (R1-R2) functions in absorption, the posterior (R4-R5) plays a role in reabsorption, and the middle acidic region (R3), which contains the copper cells (adult cuprophilic cell), in secretion and absorption.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0208023
database_cross_reference: FlyBase:FBrf0221749

Axiom
annotated source: adult midgut
annotated property: hasExactSynonym
annotated target: adult ventriculus
database_cross_reference: FlyBase:FBrf0007735

adult proventriculus
type: Class
subclass of: proventriculus
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007513
subclass of: Restriction
  on property: overlaps
  some values from: adult foregut
subclass of: Restriction
  on property: overlaps
  some values from: adult midgut
definition: Bulb-shaped organ at the junction of the foregut and midgut that regulates the passage of food into the midgut. The proventriculus folds back on itself to produce three epithelial layers: internally the posterior region of the esophagus, an intermediate (recurrent) layer, derived from the ectodermal foregut and the midgut, and an external anterior projection of the endodermal midgut, which grows over the esophageal region. The inner two layers form the gastric valve (cardial valve) while the outer layer is defined as the wall of the proventriculus. The cuticle that lines the inner wall is thicker than other regions in the cardia, and it forms several longitudinal folds, causing the esophageal lumen to appear irregular in cross section. Between the inner and intermediate layers is the hilus which contains muscle in a fibrous extracellular matrix. Between the intermediate and outer wall is the cardia lumen, which opens posteriorly into the lumen of the midgut. The anterior region secretes the peritrophic membrane into the cardia lumen.
has exact synonym: adult cardia
has OBO namespace: fly_anatomy.ontology
has related synonym: adult cardiac valve
has related synonym: adult gastric valve
id: FBbt:00003139
in subset: cur
comment: This structure is more correctly referred to as the 'cardia'. Strictly, proventriculus refers to a modification of the foregut, just anterior to the stomodeal valve, found in many insects. Drosophila has no such foregut modification (Miller, 1950). However, the term 'proventriculus' is the one most commonly used for this structure, derived from both the foregut and midgut.

Axiom
annotated source: adult proventriculus
annotated property: definition
annotated target: Bulb-shaped organ at the junction of the foregut and midgut that regulates the passage of food into the midgut. The proventriculus folds back on itself to produce three epithelial layers: internally the posterior region of the esophagus, an intermediate (recurrent) layer, derived from the ectodermal foregut and the midgut, and an external anterior projection of the endodermal midgut, which grows over the esophageal region. The inner two layers form the gastric valve (cardial valve) while the outer layer is defined as the wall of the proventriculus. The cuticle that lines the inner wall is thicker than other regions in the cardia, and it forms several longitudinal folds, causing the esophageal lumen to appear irregular in cross section. Between the inner and intermediate layers is the hilus which contains muscle in a fibrous extracellular matrix. Between the intermediate and outer wall is the cardia lumen, which opens posteriorly into the lumen of the midgut. The anterior region secretes the peritrophic membrane into the cardia lumen.
database_cross_reference: FlyBase:FBrf0007732
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0048518
database_cross_reference: FlyBase:FBrf0064792

Axiom
annotated source: adult proventriculus
annotated property: hasExactSynonym
annotated target: adult cardia
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: adult proventriculus
annotated property: hasRelatedSynonym
annotated target: adult cardiac valve
database_cross_reference: FlyBase:FBrf0064792

Axiom
annotated source: adult proventriculus
annotated property: hasRelatedSynonym
annotated target: adult gastric valve
database_cross_reference: FlyBase:FBrf0064792

adult hindgut
type: Class
subclass of: hindgut
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007513
subclass of: Restriction
  on property: develops from
  some values from: larval hindgut imaginal ring
definition: Posterior part of the of the adult alimentary canal, extending from the posterior end of the midgut, where the Malpighian tubules meet, to the rectum, including the rectal pouch and rectal papillae (Miller, 1950; Skaer, 1993; Demerec, 1994). It has a characteristic loop morphology that forms independently of the rotation of the genitalia (Gonzalez-Morales et al., 2015).
has broad synonym: adult intestine
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003143
in subset: cur

Axiom
annotated source: adult hindgut
annotated property: definition
annotated target: Posterior part of the of the adult alimentary canal, extending from the posterior end of the midgut, where the Malpighian tubules meet, to the rectum, including the rectal pouch and rectal papillae (Miller, 1950; Skaer, 1993; Demerec, 1994). It has a characteristic loop morphology that forms independently of the rotation of the genitalia (Gonzalez-Morales et al., 2015).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0075527
database_cross_reference: FlyBase:FBrf0228784

Axiom
annotated source: adult hindgut
annotated property: hasBroadSynonym
annotated target: adult intestine
database_cross_reference: FlyBase:FBrf0007735

adult posterior hindgut
type: Class
subclass of: rectum
subclass of: Restriction
  on property: part of
  some values from: adult hindgut
definition: Posterior-most region of the adult hindgut. It consists of a broadly expanded rectal sac (rectal ampulla) that tapers posteriorly to the narrow rectum proper, terminating at the anus. Protruding from the walls into the lumen of the rectal sac are two pairs of conical rectal papillae.
has exact synonym: adult rectum
has exact synonym: posterior intestine
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003144
in subset: cur

Axiom
annotated source: adult posterior hindgut
annotated property: definition
annotated target: Posterior-most region of the adult hindgut. It consists of a broadly expanded rectal sac (rectal ampulla) that tapers posteriorly to the narrow rectum proper, terminating at the anus. Protruding from the walls into the lumen of the rectal sac are two pairs of conical rectal papillae.
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: adult posterior hindgut
annotated property: hasExactSynonym
annotated target: adult rectum
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: adult posterior hindgut
annotated property: hasExactSynonym
annotated target: posterior intestine
database_cross_reference: FlyBase:FBrf0007735

adult circulatory system
type: Class
equivalent class: Class
  intersection of: circulatory system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: circulatory system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Circulatory system of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003149
in subset: cur

Axiom
annotated source: adult circulatory system
annotated property: definition
annotated target: Circulatory system of the adult.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0031012

adult dorsal vessel
type: Class
equivalent class: Class
  intersection of: FBbt_00058291
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: FBbt_00058291
subclass of: Restriction
  on property: part of
  some values from: adult circulatory system
definition: Dorsal vessel of the adult. It extends from the sixth abdominal segment to the dorsal anterior region of the brain (Curtis et al., 1999). The anterior portion, which is devoid of ostia, is the aorta, whilst the posterior (caudal) region, which has ostia, forms the heart proper.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003152
in subset: cur

Axiom
annotated source: adult dorsal vessel
annotated property: definition
annotated target: Dorsal vessel of the adult. It extends from the sixth abdominal segment to the dorsal anterior region of the brain (Curtis et al., 1999). The anterior portion, which is devoid of ostia, is the aorta, whilst the posterior (caudal) region, which has ostia, forms the heart proper.
database_cross_reference: FlyBase:FBrf0108687

adult heart
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: adult dorsal vessel
subclass of: Restriction
  on property: continuous with
  some values from: abdominal tergite 6
subclass of: Restriction
  on property: continuous with
  some values from: FBbt_00100783
definition: The caudal, pulsatile region of the adult dorsal vessel. It extends from the first to the sixth abdominal segment, lying just below the surface of the cuticle, and has four pairs of ostia (Curtis et al., 1999). It is supported along the midline of the body by a series of paired alary muscles, suspensory fibrils and a rudimentary dorsal diaphragm (Miller, 1950). The caudal end is closed and is attached to the 6th abdominal tergite and to the dorsal wall of the rectal sac. The wall of the heart consists of a single muscular layer containing circular striated fibers and scattered lateral nuclei. On the ventral side, an outer layer or longitudinal muscles extends the whole length except for the caudal end.
database_cross_reference: UBERON:0015230
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003154
in subset: cur

Axiom
annotated source: adult heart
annotated property: definition
annotated target: The caudal, pulsatile region of the adult dorsal vessel. It extends from the first to the sixth abdominal segment, lying just below the surface of the cuticle, and has four pairs of ostia (Curtis et al., 1999). It is supported along the midline of the body by a series of paired alary muscles, suspensory fibrils and a rudimentary dorsal diaphragm (Miller, 1950). The caudal end is closed and is attached to the 6th abdominal tergite and to the dorsal wall of the rectal sac. The wall of the heart consists of a single muscular layer containing circular striated fibers and scattered lateral nuclei. On the ventral side, an outer layer or longitudinal muscles extends the whole length except for the caudal end.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0108687

adult oenocyte
type: Class
subclass of: oenocyte
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007317
definition: Large, acidophilic cell found in rows under the epidermis of each abdominal segment. Two dorsal rows run from the heart tube to the spiracle, close to the posterior boundary of the segment. A single, or sometimes split, transverse row is found under each sternite.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003185
in subset: cur

Axiom
annotated source: adult oenocyte
annotated property: definition
annotated target: Large, acidophilic cell found in rows under the epidermis of each abdominal segment. Two dorsal rows run from the heart tube to the spiracle, close to the posterior boundary of the segment. A single, or sometimes split, transverse row is found under each sternite.
database_cross_reference: FlyBase:FBrf0007735

adult adipose system
type: Class
equivalent class: Class
  intersection of: adipose system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adipose system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Adipose system of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003208
in subset: cur

Axiom
annotated source: adult adipose system
annotated property: definition
annotated target: Adipose system of the adult.
database_cross_reference: FBC:SPR

adult fat body
type: Class
equivalent class: Class
  intersection of: fat body
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: fat body
subclass of: Restriction
  on property: part of
  some values from: adult adipose system
definition: Fat body of the adult. It is composed of diploid cells derived from cell clusters in the larval body wall and from adepithelial cells of the imaginal discs (Hoshizaki et al., 1995; Musselman and Kuhnlein, 2018). It is composed of various unconnected adipose tissue depots throughout the body (Musselman and Kuhnlein, 2018).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003209
in subset: cur

Axiom
annotated source: adult fat body
annotated property: definition
annotated target: Fat body of the adult. It is composed of diploid cells derived from cell clusters in the larval body wall and from adepithelial cells of the imaginal discs (Hoshizaki et al., 1995; Musselman and Kuhnlein, 2018). It is composed of various unconnected adipose tissue depots throughout the body (Musselman and Kuhnlein, 2018).
database_cross_reference: FlyBase:FBrf0064793
database_cross_reference: FlyBase:FBrf0083200
database_cross_reference: FlyBase:FBrf0238315

adult abdominal fat mass
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: adult abdomen
subclass of: Restriction
  on property: part of
  some values from: adult fat body
definition: Fat body of the adult abdomen.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003213
in subset: cur

Axiom
annotated source: adult abdominal fat mass
annotated property: definition
annotated target: Fat body of the adult abdomen.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult endocrine system
type: Class
equivalent class: Class
  intersection of: endocrine system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: endocrine system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Endocrine system of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003214
in subset: cur

Axiom
annotated source: adult endocrine system
annotated property: definition
annotated target: Endocrine system of the adult.
database_cross_reference: FBC:SPR

adult muscle system
type: Class
equivalent class: Class
  intersection of: muscle system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: muscle system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Muscle system of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003218
in subset: cur

Axiom
annotated source: adult muscle system
annotated property: definition
annotated target: Muscle system of the adult.
database_cross_reference: FlyBase:FBrf0007735

adepithelial cell
type: Class
subclass of: embryonic precursor cell of adult muscle
subclass of: Restriction
  on property: continuous with
  some values from: imaginal disc
definition: Small, spindle-shaped adult muscle precursor cell that is distinct from, but closely apposed to, the surface of an imaginal disc epithelium.
database_cross_reference: CL:0000462
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003219
in subset: cur

Axiom
annotated source: adepithelial cell
annotated property: definition
annotated target: Small, spindle-shaped adult muscle precursor cell that is distinct from, but closely apposed to, the surface of an imaginal disc epithelium.
database_cross_reference: FlyBase:FBrf0064793

adepithelial cell of eye-antennal disc
type: Class
equivalent class: Class
  intersection of: adepithelial cell
  intersection of: Restriction
    on property: continuous with
    some values from: eye-antennal disc
subclass of: adepithelial cell
subclass of: Restriction
  on property: continuous with
  some values from: eye-antennal disc
definition: Any adepithelial cell (FBbt:00003219) that is connected to some eye-antennal disc (FBbt:00001766).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003222
in subset: cur

Axiom
annotated source: adepithelial cell of eye-antennal disc
annotated property: definition
annotated target: Any adepithelial cell (FBbt:00003219) that is connected to some eye-antennal disc (FBbt:00001766).
database_cross_reference: FBC:Autogenerated

adepithelial cell of dorsal prothoracic disc
type: Class
equivalent class: Class
  intersection of: adepithelial cell
  intersection of: Restriction
    on property: continuous with
    some values from: humeral disc
subclass of: adepithelial cell
subclass of: thoracic adult muscle precursor cell
subclass of: Restriction
  on property: part of
  some values from: larval prothoracic segment
subclass of: Restriction
  on property: continuous with
  some values from: humeral disc
definition: Any adepithelial cell (FBbt:00003219) that is connected to some humeral disc (FBbt:00001777).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003223
in subset: cur

Axiom
annotated source: adepithelial cell of dorsal prothoracic disc
annotated property: definition
annotated target: Any adepithelial cell (FBbt:00003219) that is connected to some humeral disc (FBbt:00001777).
database_cross_reference: FBC:Autogenerated

adepithelial cell of prothoracic leg disc
type: Class
equivalent class: Class
  intersection of: FBbt_00100788
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: FBbt_00100788
subclass of: Restriction
  on property: part of
  some values from: larval prothoracic segment
subclass of: Restriction
  on property: continuous with
  some values from: prothoracic leg disc
definition: Adepithelial cell associated with the prothoracic leg imaginal disc.
has alternative id: FBbt:00100791
has exact synonym: adepithelial cell of ventral prothoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003224
in subset: cur

Axiom
annotated source: adepithelial cell of prothoracic leg disc
annotated property: definition
annotated target: Adepithelial cell associated with the prothoracic leg imaginal disc.
database_cross_reference: FlyBase:FBrf0093123

adepithelial cell of wing disc
type: Class
equivalent class: Class
  intersection of: adepithelial cell
  intersection of: Restriction
    on property: continuous with
    some values from: wing disc
subclass of: adepithelial cell
subclass of: thoracic adult muscle precursor cell
subclass of: Restriction
  on property: part of
  some values from: larval mesothoracic segment
subclass of: Restriction
  on property: continuous with
  some values from: wing disc
definition: Adepithelial cell associated with the wing imaginal disc. There are approximately 10 of these cells per wing disc at the end of embryogenesis; they proliferate throughout the larval stages to reach up to 2,500 cells by the late third instar larval stage. They give rise to the direct and indirect flight muscles of the adult (Gunage et al., 2014).
has alternative id: FBbt:00100786
has exact synonym: adepithelial cell of dorsal mesothoracic disc
has exact synonym: adult flight muscle precursor cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003225
in subset: cur

Axiom
annotated source: adepithelial cell of wing disc
annotated property: definition
annotated target: Adepithelial cell associated with the wing imaginal disc. There are approximately 10 of these cells per wing disc at the end of embryogenesis; they proliferate throughout the larval stages to reach up to 2,500 cells by the late third instar larval stage. They give rise to the direct and indirect flight muscles of the adult (Gunage et al., 2014).
database_cross_reference: FlyBase:FBrf0093123
database_cross_reference: FlyBase:FBrf0226374

Axiom
annotated source: adepithelial cell of wing disc
annotated property: hasExactSynonym
annotated target: adult flight muscle precursor cell
database_cross_reference: FlyBase:FBrf0226374

adepithelial cell of mesothoracic leg disc
type: Class
equivalent class: Class
  intersection of: FBbt_00100788
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: FBbt_00100788
subclass of: Restriction
  on property: part of
  some values from: larval mesothoracic segment
subclass of: Restriction
  on property: continuous with
  some values from: mesothoracic leg disc
definition: Adepithelial cell associated with the mesothoracic leg imaginal disc.
has alternative id: FBbt:00100789
has exact synonym: adepithelial cell of ventral mesothoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003226
in subset: cur

Axiom
annotated source: adepithelial cell of mesothoracic leg disc
annotated property: definition
annotated target: Adepithelial cell associated with the mesothoracic leg imaginal disc.
database_cross_reference: FlyBase:FBrf0093123

adepithelial cell of haltere disc
type: Class
equivalent class: Class
  intersection of: adepithelial cell
  intersection of: Restriction
    on property: continuous with
    some values from: haltere disc
subclass of: adepithelial cell
subclass of: thoracic adult muscle precursor cell
subclass of: Restriction
  on property: part of
  some values from: larval metathoracic segment
subclass of: Restriction
  on property: continuous with
  some values from: haltere disc
definition: Adepithelial cell associated with the haltere imaginal disc.
has alternative id: FBbt:00100787
has exact synonym: adepithelial cell of dorsal metathoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003227
in subset: cur

Axiom
annotated source: adepithelial cell of haltere disc
annotated property: definition
annotated target: Adepithelial cell associated with the haltere imaginal disc.
database_cross_reference: FlyBase:FBrf0093123

adepithelial cell of metathoracic leg disc
type: Class
equivalent class: Class
  intersection of: FBbt_00100788
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: FBbt_00100788
subclass of: Restriction
  on property: part of
  some values from: larval metathoracic segment
subclass of: Restriction
  on property: continuous with
  some values from: metathoracic leg disc
definition: Adepithelial cell associated with the metathoracic leg imaginal disc.
has alternative id: FBbt:00100790
has exact synonym: adepithelial cell of ventral metathoracic disc
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003228
in subset: cur

Axiom
annotated source: adepithelial cell of metathoracic leg disc
annotated property: definition
annotated target: Adepithelial cell associated with the metathoracic leg imaginal disc.
database_cross_reference: FlyBase:FBrf0093123

adepithelial cell of genital disc
type: Class
equivalent class: Class
  intersection of: adepithelial cell
  intersection of: Restriction
    on property: continuous with
    some values from: genital disc
subclass of: adepithelial cell
subclass of: Restriction
  on property: part of
  some values from: larval abdomen
subclass of: Restriction
  on property: continuous with
  some values from: genital disc
definition: Adepithelial cell associated with the genital imaginal disc.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003229
in subset: cur

Axiom
annotated source: adepithelial cell of genital disc
annotated property: definition
annotated target: Adepithelial cell associated with the genital imaginal disc.
database_cross_reference: FBC:SPR

adepithelial cell of female genital disc
type: Class
equivalent class: Class
  intersection of: adepithelial cell of genital disc
  intersection of: Restriction
    on property: continuous with
    some values from: female genital disc
subclass of: adepithelial cell of genital disc
subclass of: abdominal adult muscle precursor cell
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 8
subclass of: Restriction
  on property: continuous with
  some values from: female genital disc
definition: Any adepithelial cell of genital disc (FBbt:00003229) that is connected to some female genital disc (FBbt:00001787).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003230
in subset: cur

Axiom
annotated source: adepithelial cell of female genital disc
annotated property: definition
annotated target: Any adepithelial cell of genital disc (FBbt:00003229) that is connected to some female genital disc (FBbt:00001787).
database_cross_reference: FBC:Autogenerated

adepithelial cell of male genital disc
type: Class
equivalent class: Class
  intersection of: adepithelial cell of genital disc
  intersection of: Restriction
    on property: continuous with
    some values from: male genital disc
subclass of: adepithelial cell of genital disc
subclass of: abdominal adult muscle precursor cell
subclass of: Restriction
  on property: part of
  some values from: larval abdominal segment 9
subclass of: Restriction
  on property: continuous with
  some values from: male genital disc
definition: Any adepithelial cell of genital disc (FBbt:00003229) that is connected to some male genital disc (FBbt:00001785).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003231
in subset: cur

Axiom
annotated source: adepithelial cell of male genital disc
annotated property: definition
annotated target: Any adepithelial cell of genital disc (FBbt:00003229) that is connected to some male genital disc (FBbt:00001785).
database_cross_reference: FBC:Autogenerated

embryonic precursor cell of adult muscle
type: Class
subclass of: myoblast
subclass of: FBbt_00026000
subclass of: Restriction
  on property: develops from
  some values from: embryonic primordium of adult muscle precursor
definition: Cell persisting from the embryonic stage that contributes to the adult musculature. During metamorphosis, myoblasts aggregate and fuse together to form the adult muscle either on the remnants of larval muscles or independently on the newly forming adult epidermis (Bate, 1993).
has exact synonym: adult muscle precursor cell
has exact synonym: adult myoblast
has OBO namespace: fly_anatomy.ontology
has related synonym: AMP
has related synonym: P1 AdMus
id: FBbt:00003232
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic precursor cell of adult muscle
annotated property: definition
annotated target: Cell persisting from the embryonic stage that contributes to the adult musculature. During metamorphosis, myoblasts aggregate and fuse together to form the adult muscle either on the remnants of larval muscles or independently on the newly forming adult epidermis (Bate, 1993).
database_cross_reference: FlyBase:FBrf0053819
database_cross_reference: FlyBase:FBrf0064793

Axiom
annotated source: embryonic precursor cell of adult muscle
annotated property: hasExactSynonym
annotated target: adult myoblast
database_cross_reference: FlyBase:FBrf0064793

Axiom
annotated source: embryonic precursor cell of adult muscle
annotated property: hasRelatedSynonym
annotated target: P1 AdMus
database_cross_reference: https://orcid.org/0000-0002-7073-9172

thoracic adult muscle precursor cell
type: Class
equivalent class: Class
  intersection of: embryonic precursor cell of adult muscle
  intersection of: Restriction
    on property: part of
    some values from: thoracic segment
subclass of: embryonic precursor cell of adult muscle
subclass of: Restriction
  on property: part of
  some values from: thoracic segment
definition: Any embryonic precursor cell of adult muscle (FBbt:00003232) that is part of some thoracic segment (FBbt:00000016).
has exact synonym: adult thoracic myoblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003233
in subset: cur

Axiom
annotated source: thoracic adult muscle precursor cell
annotated property: definition
annotated target: Any embryonic precursor cell of adult muscle (FBbt:00003232) that is part of some thoracic segment (FBbt:00000016).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: thoracic adult muscle precursor cell
annotated property: hasExactSynonym
annotated target: adult thoracic myoblast
database_cross_reference: FlyBase:FBrf0064793

abdominal adult muscle precursor cell
type: Class
equivalent class: Class
  intersection of: embryonic precursor cell of adult muscle
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment
subclass of: embryonic precursor cell of adult muscle
subclass of: Restriction
  on property: part of
  some values from: abdominal segment
definition: An adult muscle precursor cell found in an abdominal segment. In each of embryonic segments A1-7, there are four main clusters of these cells (dorsal, dorso-lateral, lateral and ventral) (Bate, et al., 1991) that are associated with peripheral nerves (Bate, 1993) and, during late embryogenesis, are connected to each other by a network of fine filopodia (Figeac et al., 2010). During metamorphosis, they migrate along the nerves to the sites of muscle formation at the epidermal histoblast nests (Bate, 1993).
has exact synonym: adult abdominal myoblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003234
in subset: cur

Axiom
annotated source: abdominal adult muscle precursor cell
annotated property: definition
annotated target: An adult muscle precursor cell found in an abdominal segment. In each of embryonic segments A1-7, there are four main clusters of these cells (dorsal, dorso-lateral, lateral and ventral) (Bate, et al., 1991) that are associated with peripheral nerves (Bate, 1993) and, during late embryogenesis, are connected to each other by a network of fine filopodia (Figeac et al., 2010). During metamorphosis, they migrate along the nerves to the sites of muscle formation at the epidermal histoblast nests (Bate, 1993).
database_cross_reference: FlyBase:FBrf0053819
database_cross_reference: FlyBase:FBrf0064793
database_cross_reference: FlyBase:FBrf0210887

Axiom
annotated source: abdominal adult muscle precursor cell
annotated property: hasExactSynonym
annotated target: adult abdominal myoblast
database_cross_reference: FlyBase:FBrf0064793

adult somatic muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058784
subclass of: somatic muscle cell
subclass of: FBbt_00058230
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058784
definition: Any muscle cell (FBbt:00005074) that is part of some adult somatic muscle (FBbt:00058784).
database_cross_reference: UBERON:6003259
has exact synonym: adult skeletal muscle cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003259
in subset: cur

Axiom
annotated source: adult somatic muscle cell
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some adult somatic muscle (FBbt:00058784).
database_cross_reference: FBC:Autogenerated

adult somatic muscle cell of head
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058785
subclass of: adult somatic muscle cell
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058785
definition: Any muscle cell (FBbt:00005074) that is part of some adult somatic muscle of head (FBbt:00058785).
has exact synonym: skeletal muscle cell of head
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003260
in subset: cur

Axiom
annotated source: adult somatic muscle cell of head
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some adult somatic muscle of head (FBbt:00058785).
database_cross_reference: FBC:Autogenerated

adult somatic muscle cell of thorax
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058828
subclass of: adult somatic muscle cell
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058828
definition: Any muscle cell (FBbt:00005074) that is part of some adult somatic muscle of thorax (FBbt:00058828).
has exact synonym: skeletal muscle cell of thorax
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003305
in subset: cur

Axiom
annotated source: adult somatic muscle cell of thorax
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some adult somatic muscle of thorax (FBbt:00058828).
database_cross_reference: FBC:Autogenerated

muscle cell of leg muscle of leg
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058841
subclass of: FBbt_00053106
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058841
definition: Muscle cell that is part of a leg muscle of leg.
has broad synonym: skeletal muscle cell of leg
has broad synonym: somatic muscle cell of leg
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003318
in subset: cur

Axiom
annotated source: muscle cell of leg muscle of leg
annotated property: definition
annotated target: Muscle cell that is part of a leg muscle of leg.
database_cross_reference: FBC:Autogenerated

somatic muscle cell of prothorax
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058856
subclass of: adult somatic muscle cell of thorax
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058856
definition: Any muscle cell (FBbt:00005074) that is part of some somatic muscle of prothorax (FBbt:00058856).
has exact synonym: skeletal muscle cell of prothorax
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003334
in subset: cur

Axiom
annotated source: somatic muscle cell of prothorax
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some somatic muscle of prothorax (FBbt:00058856).
database_cross_reference: FBC:Autogenerated

muscle cell of adult prothoracic leg muscle
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058865
subclass of: somatic muscle cell of prothorax
subclass of: FBbt_00053106
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058865
definition: Muscle cell that is part of a adult prothoracic leg muscle.
has exact synonym: skeletal muscle cell of prothoracic leg
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003343
in subset: cur

Axiom
annotated source: muscle cell of adult prothoracic leg muscle
annotated property: definition
annotated target: Muscle cell that is part of a adult prothoracic leg muscle.
database_cross_reference: FBC:Autogenerated

somatic muscle cell of mesothorax
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058880
subclass of: adult somatic muscle cell of thorax
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058880
definition: Any muscle cell (FBbt:00005074) that is part of some somatic muscle of mesothorax (FBbt:00058880).
has exact synonym: skeletal muscle cell of mesothorax
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003359
in subset: cur

Axiom
annotated source: somatic muscle cell of mesothorax
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some somatic muscle of mesothorax (FBbt:00058880).
database_cross_reference: FBC:Autogenerated

flight muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058881
subclass of: BFO_0000040
subclass of: somatic muscle cell of mesothorax
subclass of: FBbt_00026000
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058881
subclass of: Restriction
  on property: develops from
  some values from: adepithelial cell of wing disc
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0060361
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: FBbt_00047247
definition: Any muscle cell (FBbt:00005074) that is part of some flight muscle (FBbt:00058881).
database_cross_reference: CL:0000196
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003360
in subset: cur

Axiom
annotated source: flight muscle cell
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some flight muscle (FBbt:00058881).
database_cross_reference: FBC:Autogenerated

indirect flight muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058882
subclass of: flight muscle cell
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058882
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00058198
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: indirect flight muscle motor neuron
definition: Any muscle cell (FBbt:00005074) that is part of some indirect flight muscle (FBbt:00058882).
has exact synonym: IFM cell
has exact synonym: fibrillar muscle cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003361
in subset: cur

Axiom
annotated source: indirect flight muscle cell
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some indirect flight muscle (FBbt:00058882).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: indirect flight muscle cell
annotated property: hasExactSynonym
annotated target: IFM cell
database_cross_reference: FlyBase:FBrf0064793

Axiom
annotated source: indirect flight muscle cell
annotated property: hasExactSynonym
annotated target: fibrillar muscle cell
database_cross_reference: FlyBase:FBrf0064793

muscle cell of adult mesothoracic leg muscle
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058923
subclass of: somatic muscle cell of mesothorax
subclass of: FBbt_00053106
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058923
definition: Muscle cell that is part of a adult mesothoracic leg muscle.
has exact synonym: skeletal muscle cell of mesothoracic leg
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003402
in subset: cur

Axiom
annotated source: muscle cell of adult mesothoracic leg muscle
annotated property: definition
annotated target: Muscle cell that is part of a adult mesothoracic leg muscle.
database_cross_reference: FBC:Autogenerated

somatic muscle cell of metathorax
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058937
subclass of: adult somatic muscle cell of thorax
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058937
definition: Any muscle cell (FBbt:00005074) that is part of some somatic muscle of metathorax (FBbt:00058937).
has exact synonym: skeletal muscle cell of metathorax
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003417
in subset: cur

Axiom
annotated source: somatic muscle cell of metathorax
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some somatic muscle of metathorax (FBbt:00058937).
database_cross_reference: FBC:Autogenerated

muscle cell of adult metathoracic leg muscle
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058950
subclass of: somatic muscle cell of metathorax
subclass of: FBbt_00053106
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058950
definition: Muscle cell that is part of a adult metathoracic leg muscle.
has exact synonym: skeletal muscle cell of metathoracic leg
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003430
in subset: cur

Axiom
annotated source: muscle cell of adult metathoracic leg muscle
annotated property: definition
annotated target: Muscle cell that is part of a adult metathoracic leg muscle.
database_cross_reference: FBC:Autogenerated

adult somatic muscle cell of abdomen
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058966
subclass of: adult somatic muscle cell
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058966
definition: Any muscle cell (FBbt:00005074) that is part of some adult somatic muscle of abdomen (FBbt:00058966).
has exact synonym: skeletal muscle cell of abdomen
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003447
in subset: cur

Axiom
annotated source: adult somatic muscle cell of abdomen
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some adult somatic muscle of abdomen (FBbt:00058966).
database_cross_reference: FBC:Autogenerated

male abdominal muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00059016
subclass of: adult somatic muscle cell of abdomen
subclass of: FBbt_00048490
subclass of: Restriction
  on property: part of
  some values from: FBbt_00059016
definition: Any muscle cell (FBbt:00005074) that is part of some male abdominal muscle (FBbt:00059016).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003505
in subset: cur

Axiom
annotated source: male abdominal muscle cell
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some male abdominal muscle (FBbt:00059016).
database_cross_reference: FBC:Autogenerated

female abdominal somatic muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00059018
subclass of: adult somatic muscle cell of abdomen
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: FBbt_00059018
definition: Any muscle cell (FBbt:00005074) that is part of some female abdominal somatic muscle (FBbt:00059018).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003507
in subset: cur

Axiom
annotated source: female abdominal somatic muscle cell
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some female abdominal somatic muscle (FBbt:00059018).
database_cross_reference: FBC:Autogenerated

adult apodeme
type: Class
equivalent class: Class
  intersection of: apodeme
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: apodeme
subclass of: Restriction
  on property: part of
  some values from: adult integumentary system
definition: Apodeme that is part of an adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003516
in subset: cur
in subset: hidden assertion

Axiom
annotated source: adult apodeme
annotated property: definition
annotated target: Apodeme that is part of an adult.
database_cross_reference: FBC:SPR

adult visceral muscle cell
type: Class
equivalent class: Class
  intersection of: visceral muscle cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: visceral muscle cell
subclass of: FBbt_00058230
definition: Muscle cell of a visceral muscle of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003525
in subset: cur
in subset: hidden assertion

Axiom
annotated source: adult visceral muscle cell
annotated property: definition
annotated target: Muscle cell of a visceral muscle of the adult.
database_cross_reference: FlyBase:FBrf0041814
database_cross_reference: FlyBase:FBrf0064793

adult longitudinal muscle cell
type: Class
subclass of: adult visceral muscle cell
definition: Muscle cell of a longitudinal muscle of the adult. These muscles surrounds the intestinal tract and ducts of the reproductive system, together with a layer of circular muscle.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003526
in subset: cur

Axiom
annotated source: adult longitudinal muscle cell
annotated property: definition
annotated target: Muscle cell of a longitudinal muscle of the adult. These muscles surrounds the intestinal tract and ducts of the reproductive system, together with a layer of circular muscle.
database_cross_reference: FlyBase:FBrf0064793

hindgut muscle cell
type: Class
equivalent class: Class
  intersection of: visceral muscle cell
  intersection of: Restriction
    on property: part of
    some values from: hindgut
subclass of: visceral muscle cell
subclass of: Restriction
  on property: part of
  some values from: hindgut
definition: Cell that are part of the muscle fibers of the hindgut, the posterior part of the alimentary canal. It contains longitudinal and circular muscle fibers.
has broad synonym: intestine muscle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003537
in subset: cur

Axiom
annotated source: hindgut muscle cell
annotated property: definition
annotated target: Cell that are part of the muscle fibers of the hindgut, the posterior part of the alimentary canal. It contains longitudinal and circular muscle fibers.
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: hindgut muscle cell
annotated property: hasBroadSynonym
annotated target: intestine muscle
database_cross_reference: FlyBase:FBrf0007735

adult heart muscle cell
type: Class
subclass of: adult visceral muscle cell
subclass of: Restriction
  on property: part of
  some values from: adult heart
definition: Muscle cell of a muscle of the adult that is associated with the heart.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003543
in subset: cur

Axiom
annotated source: adult heart muscle cell
annotated property: definition
annotated target: Muscle cell of a muscle of the adult that is associated with the heart.
database_cross_reference: FlyBase:FBrf0007735

adult alary muscle cell
type: Class
subclass of: adult heart muscle cell
subclass of: Restriction
  on property: attached to
  some values from: adult heart
definition: Muscle cell of a bilateral adult heart muscle that is involved in modulation of the flow of hemolymph into the cardiac tube, and support of the dorsal vessel during locomotion.
has exact synonym: AlMsc
has OBO namespace: fly_anatomy.ontology
has related synonym: am
id: FBbt:00003545
in subset: cur

Axiom
annotated source: adult alary muscle cell
annotated property: definition
annotated target: Muscle cell of a bilateral adult heart muscle that is involved in modulation of the flow of hemolymph into the cardiac tube, and support of the dorsal vessel during locomotion.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0064793
database_cross_reference: FlyBase:FBrf0208061

Axiom
annotated source: adult alary muscle cell
annotated property: hasExactSynonym
annotated target: AlMsc
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: adult alary muscle cell
annotated property: hasRelatedSynonym
annotated target: am
database_cross_reference: FlyBase:FBrf0208061

adult heart ventral longitudinal muscle cell
type: Class
subclass of: adult longitudinal muscle cell
subclass of: adult heart muscle cell
definition: Muscle cell of the longitudinal muscle of the adult heart that spreads over the outer layer of the ventral side of this organ.
has exact synonym: ventral adult heart longitudinal muscle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003550
in subset: cur

Axiom
annotated source: adult heart ventral longitudinal muscle cell
annotated property: definition
annotated target: Muscle cell of the longitudinal muscle of the adult heart that spreads over the outer layer of the ventral side of this organ.
database_cross_reference: FlyBase:FBrf0139748

gonadal sheath muscle cell
type: Class
equivalent class: Class
  intersection of: adult visceral muscle cell
  intersection of: Restriction
    on property: part of
    some values from: gonadal sheath
subclass of: adult visceral muscle cell
subclass of: Restriction
  on property: part of
  some values from: gonadal sheath
definition: Muscle cell of a muscle that is part of an adult gonadal sheath.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003556
in subset: cur

Axiom
annotated source: gonadal sheath muscle cell
annotated property: definition
annotated target: Muscle cell of a muscle that is part of an adult gonadal sheath.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult nervous system
type: Class
equivalent class: Class
  intersection of: nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: nervous system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Any nervous system of the adult.
database_cross_reference: UBERON:6003559
database_cross_reference: VFB:FBbt_00003559
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003559
in subset: cur

Axiom
annotated source: adult nervous system
annotated property: definition
annotated target: Any nervous system of the adult.
database_cross_reference: FlyBase:FBrf0002482
database_cross_reference: FlyBase:FBrf0007196
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0034076

thoracic neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: part of
    some values from: thoracic segment
subclass of: neuroblast of ventral nervous system
subclass of: Restriction
  on property: part of
  some values from: thoracic segment
definition: Any neuroblast (FBbt:00005146) that is part of some thoracic segment (FBbt:00000016).
database_cross_reference: VFB:FBbt_00003561
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003561
in subset: cur

Axiom
annotated source: thoracic neuroblast
annotated property: definition
annotated target: Any neuroblast (FBbt:00005146) that is part of some thoracic segment (FBbt:00000016).
database_cross_reference: FlyBase:FBrf0090460

abdominal neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment
subclass of: neuroblast of ventral nervous system
subclass of: Restriction
  on property: part of
  some values from: abdominal segment
definition: Any neuroblast (FBbt:00005146) that is part of some abdominal segment (FBbt:00000021).
database_cross_reference: VFB:FBbt_00003584
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003584
in subset: cur

Axiom
annotated source: abdominal neuroblast
annotated property: definition
annotated target: Any neuroblast (FBbt:00005146) that is part of some abdominal segment (FBbt:00000021).
database_cross_reference: FlyBase:FBrf0090460

adult central nervous system
type: Class
equivalent class: Class
  intersection of: central nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: central nervous system
subclass of: Restriction
  on property: part of
  some values from: adult nervous system
definition: Central nervous system of the adult.
database_cross_reference: UBERON:6003623
database_cross_reference: VFB:FBbt_00003623
has exact synonym: adult CNS
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003623
in subset: cur

Axiom
annotated source: adult central nervous system
annotated property: definition
annotated target: Central nervous system of the adult.
database_cross_reference: FBC:SPR

adult brain
type: Class
equivalent class: Class
  intersection of: brain
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: brain
subclass of: Class
  intersection of: Restriction
    on property: part of
    some values from: adult head
  intersection of: Restriction
    on property: part of
    some values from: adult central nervous system
definition: Portion of the adult central nervous system found in the head, consisting of the cerebral and gnathal ganglia (Ito et al., 2014).
database_cross_reference: UBERON:6003624
database_cross_reference: VFB:FBbt_00003624
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003624
in subset: BrainName
in subset: cur

Axiom
annotated source: adult brain
annotated property: definition
annotated target: Portion of the adult central nervous system found in the head, consisting of the cerebral and gnathal ganglia (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

adult brain cell body rind
type: Class
subclass of: FBbt_00049603
subclass of: Restriction
  on property: part of
  some values from: adult brain
definition: Superficial layer of the brain, composed of glia and the cell bodies of neurons (soma).
database_cross_reference: VFB:FBbt_00003625
has exact synonym: adult brain cortex
has OBO namespace: fly_anatomy.ontology
has related synonym: cerebral cortex
id: FBbt:00003625
in subset: cur
comment: Ito et al. (2014) may further subdivide cortex/rind regions into multiple facets. Subdivisions should be denoted by the addition of a single letter body-axis direction, e.g. rLHa for anterior to the lateral horn; rSMPm for medial to the superior medial protocerebrum, etc.

Axiom
annotated source: adult brain cell body rind
annotated property: definition
annotated target: Superficial layer of the brain, composed of glia and the cell bodies of neurons (soma).
database_cross_reference: FBC:VH

supraesophageal ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: part of
  some values from: brain
definition: The pre-oral neuropils of the brain located above and some of it below the esophagus, comprising three fused ganglia (protocerebrum, deutocerebrum, and tritocerebrum) in the head.
database_cross_reference: UBERON:6003626
database_cross_reference: VFB:FBbt_00003626
has OBO namespace: fly_anatomy.ontology
has related synonym: SPG
id: FBbt:00003626
in subset: BrainName
in subset: cur
comment: In the adult, this region is referred to as cerebral ganglia (Ito et al., 2014).

Axiom
annotated source: supraesophageal ganglion
annotated property: definition
annotated target: The pre-oral neuropils of the brain located above and some of it below the esophagus, comprising three fused ganglia (protocerebrum, deutocerebrum, and tritocerebrum) in the head.
database_cross_reference: FlyBase:FBrf0224194

protocerebrum
type: Class
subclass of: neuromere
subclass of: Restriction
  on property: part of
  some values from: FBbt_00051069
subclass of: Restriction
  on property: overlaps
  some values from: ocular segment
subclass of: Restriction
  on property: overlaps
  some values from: labral segment
definition: The most anterior neuromere of the central nervous system, developing from neuroblasts of the labral and ocular segments (Urbach and Technau, 2003; Ito et al., 2014). The protocerebrum comprises many discrete neuropil regions including the central complex and mushroom bodies (Ito et al., 2014).
database_cross_reference: UBERON:6003627
database_cross_reference: VFB:FBbt_00003627
has exact synonym: PR
has exact synonym: protocerebral neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003627
in subset: cur
comment: Urbach and Technau (2003) divide the protocerebrum into labral and ocular neuromeres.

Axiom
annotated source: protocerebrum
annotated property: definition
annotated target: The most anterior neuromere of the central nervous system, developing from neuroblasts of the labral and ocular segments (Urbach and Technau, 2003; Ito et al., 2014). The protocerebrum comprises many discrete neuropil regions including the central complex and mushroom bodies (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: protocerebrum
annotated property: hasExactSynonym
annotated target: PR
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: protocerebrum
annotated property: hasExactSynonym
annotated target: protocerebral neuromere
database_cross_reference: FlyBase:FBrf0092819

adult central complex
type: Class
subclass of: FBbt_00041000
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: develops from
  some values from: larval posterior inferior protocerebrum
definition: A midline crossing complex of the synaptic neuropil domains of the adult brain: the ellipsoid body, the fan-shaped body, the three paired noduli, the asymmetrical bodies and the protocerebral bridge. It is closely associated with another paired synaptic neuropil domain, the lateral complex. It lies in the middle of the brain between the pedunculi of the mushroom bodies and is bounded ventrally by the esophagus, dorsally by the pars intercerebralis and laterally by the antenno-glomerular tracts.
database_cross_reference: UBERON:6003632
database_cross_reference: VFB:FBbt_00003632
has exact synonym: CX
has exact synonym: adult central body complex
has OBO namespace: fly_anatomy.ontology
has related synonym: central body
has related synonym: central body complex
id: FBbt:00003632
in subset: BrainName
in subset: cur
comment: Some authors' use of the term 'central body' excludes the protocerebral bridge, some usage also excludes the noduli, some exclude the lateral triangles, and historically it has been used to refer to the fan-shaped body alone (Hanesch et al., 1989).

Axiom
annotated source: adult central complex
annotated property: definition
annotated target: A midline crossing complex of the synaptic neuropil domains of the adult brain: the ellipsoid body, the fan-shaped body, the three paired noduli, the asymmetrical bodies and the protocerebral bridge. It is closely associated with another paired synaptic neuropil domain, the lateral complex. It lies in the middle of the brain between the pedunculi of the mushroom bodies and is bounded ventrally by the esophagus, dorsally by the pars intercerebralis and laterally by the antenno-glomerular tracts.
database_cross_reference: FlyBase:FBrf0049409
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0240744

Axiom
annotated source: adult central complex
annotated property: hasExactSynonym
annotated target: CX
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

large field neuron
type: Class
subclass of: interneuron
definition: Interneuron with one or more large arborization fields relative to the neuropil domain(s) it innervates.
database_cross_reference: VFB:FBbt_00003648
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003648
in subset: cur

Axiom
annotated source: large field neuron
annotated property: definition
annotated target: Interneuron with one or more large arborization fields relative to the neuropil domain(s) it innervates.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult intrinsic protocerebral bridge neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: protocerebral bridge
subclass of: FBbt_00007515
subclass of: FBbt_00053387
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00111153
subclass of: Restriction
  on property: synapses restricted to region
  some values from: protocerebral bridge
definition: Intrinsic neuron of the adult protocerebral bridge. These neurons have somas located in the posterior cell body rind, medial and ventral to the Kenyon cell soma, and fibers that enter the protocerebral bridge laterally.
database_cross_reference: VFB:FBbt_00003666
has exact synonym: PB LN neuron
has exact synonym: intrinsic pb neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003666
in subset: cur

Axiom
annotated source: adult intrinsic protocerebral bridge neuron
annotated property: definition
annotated target: Intrinsic neuron of the adult protocerebral bridge. These neurons have somas located in the posterior cell body rind, medial and ventral to the Kenyon cell soma, and fibers that enter the protocerebral bridge laterally.
database_cross_reference: FlyBase:FBrf0049409
database_cross_reference: FlyBase:FBrf0221742

Axiom
annotated source: adult intrinsic protocerebral bridge neuron
annotated property: hasExactSynonym
annotated target: PB LN neuron
database_cross_reference: FlyBase:FBrf0221742

Axiom
annotated source: adult intrinsic protocerebral bridge neuron
annotated property: hasExactSynonym
annotated target: intrinsic pb neuron
database_cross_reference: FlyBase:FBrf0049409

protocerebral bridge
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: adult central complex
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00111206
definition: A handle bar-shaped synaptic neuropil located just posterior to the fan-shaped body. Its lateral edge ends at the posterior end of the inferior clamp (ICL) near the medial equatorial fascicle (MEF). A row of 18 connected slices (9 on each side of the midline, numbered 1-9 from medial to lateral) that forms a dorso-posteriorly located part of the central complex embedded in the cortex between the calyces of the two mushroom bodies.
database_cross_reference: VFB:FBbt_00003668
has exact synonym: PB
has exact synonym: PCB
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003668
in subset: BrainName
in subset: cur
comment: The identification of the most medial slice (slice 1) by Wolff et al. (2015) meant that the domain that was previously called slice 1 corresponds in fact to slice 2. Each of the two neighboring slices (2-3, 4-5, 6-7, 8-9) are associated more closely because small-field columnar neurons innervate the fan-shaped body via the protocerebral bridge, and these neurons are generated by the same neuroblasts, forming four groups on each side of the midline, from lateral to medial: segment pair W, X, Y and Z (Boyan and Williams et al., 2011; Ito and Awasaki, 2008).

Axiom
annotated source: protocerebral bridge
annotated property: definition
annotated target: A handle bar-shaped synaptic neuropil located just posterior to the fan-shaped body. Its lateral edge ends at the posterior end of the inferior clamp (ICL) near the medial equatorial fascicle (MEF). A row of 18 connected slices (9 on each side of the midline, numbered 1-9 from medial to lateral) that forms a dorso-posteriorly located part of the central complex embedded in the cortex between the calyces of the two mushroom bodies.
database_cross_reference: FlyBase:FBrf0049409
database_cross_reference: FlyBase:FBrf0205148
database_cross_reference: FlyBase:FBrf0213955
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0227801
database_cross_reference: VFB_vol:00003668

Axiom
annotated source: protocerebral bridge
annotated property: hasExactSynonym
annotated target: PB
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: protocerebral bridge
annotated property: hasExactSynonym
annotated target: PCB
database_cross_reference: FlyBase:FBrf0212704

ellipsoid body
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045020
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00051443
definition: A doughnut shaped synaptic neuropil domain of the central complex of the adult brain that lies just anterior to the fan-shaped body. Its hole (the ellipsoid body canal) points anteriorly and has an axon tract (the anterior bundle) running through it. It is divided into concentric layers and into 16 radial segments, 8 per hemisphere, numbered 1-8 from superior medial to inferior medial (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00003678
has exact synonym: EB
has OBO namespace: fly_anatomy.ontology
has related synonym: eb
id: FBbt:00003678
in subset: BrainName
in subset: cur

Axiom
annotated source: ellipsoid body
annotated property: definition
annotated target: A doughnut shaped synaptic neuropil domain of the central complex of the adult brain that lies just anterior to the fan-shaped body. Its hole (the ellipsoid body canal) points anteriorly and has an axon tract (the anterior bundle) running through it. It is divided into concentric layers and into 16 radial segments, 8 per hemisphere, numbered 1-8 from superior medial to inferior medial (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: ellipsoid body
annotated property: hasExactSynonym
annotated target: EB
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

fan-shaped body
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045020
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00111207
definition: The largest synaptic neuropil domain of the adult central complex, located posterior to the ellipsoid body and anterior to the protocerebral bridge (Hanesch et al., 1989; Wolff et al., 2015). The fan-shaped body is composed of a rough 2-dimensional grid of layers and columns (Hanesch et al., 1998; Wolff et al., 2015; Hulse et al., 2021). Eight horizontal layers, numbered bottom to top, form a fan shape and can be divided into vertical columns (sometimes called staves, slices or segments) (Ito et al., 2014; Wolff et al., 2015). An additional, much narrower, 9th layer, which lacks a columnar organization, sits dorsal to layer 8 (Wolff et al., 2015). The number of columns varies for different neuronal types (Scheffer et al., 2020).
database_cross_reference: VFB:FBbt_00003679
has exact synonym: FB
has exact synonym: fan shaped body
has exact synonym: fb
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003679
in subset: BrainName
in subset: cur
comment: Previously thought to be 8 slices per hemisphere numbered from 1-8 medial to lateral - arranged in 4 closely associated pairs (Ito et al., 2014). Each of the two neighboring slices (1-2, 3-4, 5-6, 7-8) are associated more closely because they receive small-field columnar neurons generated by the same neuroblasts, forming four groups on each side of the midline, from lateral to medial: segment pair W, X, Y and Z (Boyan and Williams, 2011; Ito and Awasaki, 2008). Six to nine layers can be identified, depending on the staining that is used (Hanesch et al., 1989; Young and Armstrong, 2010; Kahsai and Winther, 2011, Lin et al., 2013, Wolff et al., 2015). Recent papers divide the FB into 9 layers (Wolff et al., 2015; Scheffer et al., 2020).

Axiom
annotated source: fan-shaped body
annotated property: definition
annotated target: The largest synaptic neuropil domain of the adult central complex, located posterior to the ellipsoid body and anterior to the protocerebral bridge (Hanesch et al., 1989; Wolff et al., 2015). The fan-shaped body is composed of a rough 2-dimensional grid of layers and columns (Hanesch et al., 1998; Wolff et al., 2015; Hulse et al., 2021). Eight horizontal layers, numbered bottom to top, form a fan shape and can be divided into vertical columns (sometimes called staves, slices or segments) (Ito et al., 2014; Wolff et al., 2015). An additional, much narrower, 9th layer, which lacks a columnar organization, sits dorsal to layer 8 (Wolff et al., 2015). The number of columns varies for different neuronal types (Scheffer et al., 2020).
database_cross_reference: FlyBase:FBrf0049409
database_cross_reference: FlyBase:FBrf0212649
database_cross_reference: FlyBase:FBrf0221742
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0227801
database_cross_reference: FlyBase:FBrf0246888
database_cross_reference: FlyBase:FBrf0254510

Axiom
annotated source: fan-shaped body
annotated property: hasExactSynonym
annotated target: FB
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: fan-shaped body
annotated property: hasExactSynonym
annotated target: fb
database_cross_reference: FlyBase:FBrf0049409

adult lateral accessory lobe
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00040001
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval lateral accessory lobe
definition: A bilaterally paired synaptic neuropil domain of the adult brain with a roughly pyramidal shape that is located inferior-lateral to the ellipsoid body and anterior-inferior to the bulb (lateral triangle). It lies behind the antennal lobe and in front of the ventral complex.
has broad synonym: IDFP
database_cross_reference: VFB:FBbt_00003681
has exact synonym: LAL
has exact synonym: vbo
has exact synonym: ventral body
has OBO namespace: fly_anatomy.ontology
has related synonym: hammer body
has related synonym: vmpr
id: FBbt:00003681
in subset: BrainName
in subset: cur
comment: The LAL corresponds to part of the anterior superior part of the vmpr of Otsuna and Ito (2006) and to the ventral part of the inferior dorsofrontal protocerebrum (IDFP) of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: adult lateral accessory lobe
annotated property: definition
annotated target: A bilaterally paired synaptic neuropil domain of the adult brain with a roughly pyramidal shape that is located inferior-lateral to the ellipsoid body and anterior-inferior to the bulb (lateral triangle). It lies behind the antennal lobe and in front of the ventral complex.
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult lateral accessory lobe
annotated property: hasBroadSynonym
annotated target: IDFP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: adult lateral accessory lobe
annotated property: hasExactSynonym
annotated target: LAL
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: adult lateral accessory lobe
annotated property: hasRelatedSynonym
annotated target: hammer body
database_cross_reference: FlyBase:FBrf0221742
database_cross_reference: FlyBase:FBrf0227801

Axiom
annotated source: adult lateral accessory lobe
annotated property: hasRelatedSynonym
annotated target: vmpr
database_cross_reference: FlyBase:FBrf0193607

bulb
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00040001
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00051440
definition: A bilaterally paired synaptic neuropil domain located lateral to the ellipsoid body and anterior lateral to the fan-shaped body. It contains 80 microglomeruli characterized by their granular texture. It is formed primarily by the collateral arborizations of neuronal fibers that project to the ellipsoid body and by the terminals of the fibers projecting from the anterior optic tubercle and other neuropils.
has broad synonym: mimpr
database_cross_reference: VFB:FBbt_00003682
has exact synonym: BU
has exact synonym: Lat Tri
has exact synonym: isthmus
has exact synonym: lateral triangle
has exact synonym: ltr
has OBO namespace: fly_anatomy.ontology
has related synonym: IST
id: FBbt:00003682
in subset: BrainName
in subset: cur
comment: The bulb corresponds to the medial part of the mimpr of Otsuna and Ito, (2006) and to the lateral triangle of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: bulb
annotated property: definition
annotated target: A bilaterally paired synaptic neuropil domain located lateral to the ellipsoid body and anterior lateral to the fan-shaped body. It contains 80 microglomeruli characterized by their granular texture. It is formed primarily by the collateral arborizations of neuronal fibers that project to the ellipsoid body and by the terminals of the fibers projecting from the anterior optic tubercle and other neuropils.
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0221742
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00003682

Axiom
annotated source: bulb
annotated property: hasBroadSynonym
annotated target: mimpr
database_cross_reference: FlyBase:FBrf0193607

Axiom
annotated source: bulb
annotated property: hasExactSynonym
annotated target: BU
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: bulb
annotated property: hasExactSynonym
annotated target: Lat Tri
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: bulb
annotated property: hasRelatedSynonym
annotated target: IST
database_cross_reference: FlyBase:FBrf0224194

adult mushroom body
type: Class
subclass of: mushroom body
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00011929
definition: Bilaterally paired neuropil structure situated postero-dorsally in the protocerebrum that functions in olfactory associative learning and memory. The mushroom body is divided into: the calyx, which is closest to the cell body rind and receives sensory interneuron afferents; the pedunculus, which is a thick axon bundle extending from the calyx to the base of the lobes; and the mushroom body lobe system, which consists of a vertical branch composed of two intertwined lobes (alpha and alpha') and a medial branch consisting of three parallel lobes (beta, beta' and gamma) (Crittenden et al., 1998; Ito et al., 2014).
database_cross_reference: VFB:FBbt_00003684
has exact synonym: MB
has OBO namespace: fly_anatomy.ontology
has related synonym: corpora pedunculata
id: FBbt:00003684
in subset: cur

Axiom
annotated source: adult mushroom body
annotated property: definition
annotated target: Bilaterally paired neuropil structure situated postero-dorsally in the protocerebrum that functions in olfactory associative learning and memory. The mushroom body is divided into: the calyx, which is closest to the cell body rind and receives sensory interneuron afferents; the pedunculus, which is a thick axon bundle extending from the calyx to the base of the lobes; and the mushroom body lobe system, which consists of a vertical branch composed of two intertwined lobes (alpha and alpha') and a medial branch consisting of three parallel lobes (beta, beta' and gamma) (Crittenden et al., 1998; Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0105215
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0248215

Axiom
annotated source: adult mushroom body
annotated property: hasExactSynonym
annotated target: MB
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

mushroom body calyx
type: Class
subclass of: FBbt_00040007
subclass of: FBbt_00049824
definition: A synaptic neuropil domain containing dendrites of Kenyon cells and receiving sensory interneuron afferents, mainly from the antennal lobes (Ito et al., 2014; Saumweber et al., 2018). It is located on the posterior side of the brain, close to the cortex where the cell bodies of the Kenyon cells are located (Lee et al., 1999; Saumweber et al., 2018). The peduncle extends anteriorly from the calyx to the base of the lobes (Ito et al., 2014; Saumweber et al., 2018).
database_cross_reference: VFB:FBbt_00003685
has exact synonym: CA
has exact synonym: calyx of corpora pedunculata
has exact synonym: calyx of mushroom body
has narrow synonym: main calyx
has OBO namespace: fly_anatomy.ontology
has related synonym: calyx
id: FBbt:00003685
in subset: BrainName
in subset: cur
in subset: larval OF

Axiom
annotated source: mushroom body calyx
annotated property: definition
annotated target: A synaptic neuropil domain containing dendrites of Kenyon cells and receiving sensory interneuron afferents, mainly from the antennal lobes (Ito et al., 2014; Saumweber et al., 2018). It is located on the posterior side of the brain, close to the cortex where the cell bodies of the Kenyon cells are located (Lee et al., 1999; Saumweber et al., 2018). The peduncle extends anteriorly from the calyx to the base of the lobes (Ito et al., 2014; Saumweber et al., 2018).
database_cross_reference: FlyBase:FBrf0111409
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0238440

Axiom
annotated source: mushroom body calyx
annotated property: hasExactSynonym
annotated target: CA
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: mushroom body calyx
annotated property: hasNarrowSynonym
annotated target: main calyx
database_cross_reference: FlyBase:FBrf0205263

Kenyon cell
type: Class
subclass of: FBbt_00007484
subclass of: FBbt_00025991
subclass of: Restriction
  on property: overlaps
  some values from: mushroom body pedunculus
subclass of: Restriction
  on property: develops from
  some values from: neuroblast MBp
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: mushroom body calyx
definition: Intrinsic neuron of the mushroom body. They have tightly-packed cell bodies, situated in the rind above the calyx of the mushroom body (Ito et al., 1997). Four short fascicles, one per lineage, extend from the cell bodies of the Kenyon cells into the calyx (Ito et al., 1997). These 4 smaller fascicles converge in the calyx where they arborize and form pre- and post-synaptic terminals (Christiansen et al., 2011), with different Kenyon cells receiving input in different calyx regions/accessory calyces (Tanaka et al., 2008). They emerge from the calyx as a thick axon bundle referred to as the peduncle that bifurcates to innervate the dorsal and medial lobes of the mushroom body (Tanaka et al., 2008).
database_cross_reference: CL:0000673
database_cross_reference: VFB:FBbt_00003686
has exact synonym: KC
has exact synonym: intrinsic cell of mushroom body
has exact synonym: intrinsic neuron of mushroom body
has exact synonym: mature Kenyon cell
has OBO namespace: fly_anatomy.ontology
has related synonym: MB neuron
has related synonym: mushroom body neuron
id: FBbt:00003686
in subset: cur
comment: Pre-synaptic terminals were identified using two presynaptic markers (Brp and Dsyd-1) and post-synaptic terminals by labelling a subunit of the acetylcholine receptor (Dalpha7) in genetically labelled Kenyon cells (Christiansen et al., 2011).

Axiom
annotated source: Kenyon cell
annotated property: definition
annotated target: Intrinsic neuron of the mushroom body. They have tightly-packed cell bodies, situated in the rind above the calyx of the mushroom body (Ito et al., 1997). Four short fascicles, one per lineage, extend from the cell bodies of the Kenyon cells into the calyx (Ito et al., 1997). These 4 smaller fascicles converge in the calyx where they arborize and form pre- and post-synaptic terminals (Christiansen et al., 2011), with different Kenyon cells receiving input in different calyx regions/accessory calyces (Tanaka et al., 2008). They emerge from the calyx as a thick axon bundle referred to as the peduncle that bifurcates to innervate the dorsal and medial lobes of the mushroom body (Tanaka et al., 2008).
database_cross_reference: FlyBase:FBrf0092568
database_cross_reference: FlyBase:FBrf0205263
database_cross_reference: FlyBase:FBrf0214059

Axiom
annotated source: Kenyon cell
annotated property: hasExactSynonym
annotated target: KC
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: Kenyon cell
annotated property: hasExactSynonym
annotated target: mature Kenyon cell
database_cross_reference: FlyBase:FBrf0236359

Axiom
annotated source: Kenyon cell
annotated property: hasRelatedSynonym
annotated target: MB neuron
database_cross_reference: FlyBase:FBrf0111409

Axiom
annotated source: Kenyon cell
annotated property: hasRelatedSynonym
annotated target: mushroom body neuron
database_cross_reference: FlyBase:FBrf0111409

mushroom body pedunculus
type: Class
subclass of: FBbt_00040007
subclass of: FBbt_00049824
definition: A bundle of neuron projections of Kenyon cells, dense with synapses, that extends from the calyx of the mushroom body to the base of the mushroom body lobe system (Ito et al., 1997).
database_cross_reference: VFB:FBbt_00003687
has exact synonym: PED
has exact synonym: peduncle
has exact synonym: peduncle of mushroom body
has exact synonym: peduncule
has exact synonym: peduncule of mushroom body
has exact synonym: pedunculus
has exact synonym: stalk of corpora pedunculata
has exact synonym: stalk of mushroom body
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003687
in subset: BrainName
in subset: cur

Axiom
annotated source: mushroom body pedunculus
annotated property: definition
annotated target: A bundle of neuron projections of Kenyon cells, dense with synapses, that extends from the calyx of the mushroom body to the base of the mushroom body lobe system (Ito et al., 1997).
database_cross_reference: FlyBase:FBrf0092568

Axiom
annotated source: mushroom body pedunculus
annotated property: hasExactSynonym
annotated target: PED
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

lobe system of mushroom body
type: Class
subclass of: FBbt_00040007
subclass of: FBbt_00049824
definition: The mushroom body lobe system consists of a vertical (dorsal) branch and a medial branch. In the larva, there are only two lobes (one dorsal, one medial), but remodeling during the pupal stage results in five lobes (two dorsal, three medial) in the adult (Lee et al., 1999).
database_cross_reference: VFB:FBbt_00003688
has OBO namespace: fly_anatomy.ontology
has related synonym: lobe of corpora pedunculata
has related synonym: lobe of mushroom body
id: FBbt:00003688
in subset: BrainName
in subset: cur

Axiom
annotated source: lobe system of mushroom body
annotated property: definition
annotated target: The mushroom body lobe system consists of a vertical (dorsal) branch and a medial branch. In the larva, there are only two lobes (one dorsal, one medial), but remodeling during the pupal stage results in five lobes (two dorsal, three medial) in the adult (Lee et al., 1999).
database_cross_reference: FlyBase:FBrf0105215
database_cross_reference: FlyBase:FBrf0111409
database_cross_reference: FlyBase:FBrf0144836

optic glomerulus
type: Class
subclass of: glomerulus
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045021
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047735
definition: Small and discrete area of the ventrolateral neuropils defined by the presynaptic terminals of visual projection neurons carrying sensory information from the optic lobe (Otsuna and Ito, 2006; Wu et al., 2016).
has alternative id: FBbt:00040032
database_cross_reference: VFB:FBbt_00003698
has exact synonym: optic focus
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003698
in subset: cur

Axiom
annotated source: optic glomerulus
annotated property: definition
annotated target: Small and discrete area of the ventrolateral neuropils defined by the presynaptic terminals of visual projection neurons carrying sensory information from the optic lobe (Otsuna and Ito, 2006; Wu et al., 2016).
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: optic glomerulus
annotated property: hasExactSynonym
annotated target: optic focus
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0239031

adult optic lobe
type: Class
subclass of: multi-tissue structure
subclass of: FBbt_00053384
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047735
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval optic lobe
definition: A region of the adult brain that processes visual information from the compound eyes.
database_cross_reference: UBERON:0006795
database_cross_reference: VFB:FBbt_00003701
has exact synonym: OL
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003701
in subset: BrainName
in subset: FB gloss
in subset: cur

Axiom
annotated source: adult optic lobe
annotated property: definition
annotated target: A region of the adult brain that processes visual information from the compound eyes.
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0166419

Axiom
annotated source: adult optic lobe
annotated property: hasExactSynonym
annotated target: OL
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

adult optic lobe neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: adult optic lobe
subclass of: supraesophageal ganglion neuron
subclass of: FBbt_00025991
subclass of: FBbt_00059274
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00111152
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053539
definition: Neuron that has its cell body in the adult optic lobe. These neurons develop from neuroblasts of the larval optic anlage (Hofbauer and Campos-Ortega, 1990).
database_cross_reference: VFB:FBbt_00003702
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003702
in subset: cur

Axiom
annotated source: adult optic lobe neuron
annotated property: definition
annotated target: Neuron that has its cell body in the adult optic lobe. These neurons develop from neuroblasts of the larval optic anlage (Hofbauer and Campos-Ortega, 1990).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0052913
database_cross_reference: FlyBase:FBrf0064800
database_cross_reference: FlyBase:FBrf0226618

lamina
type: Class
subclass of: FBbt_00025991
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
subclass of: Restriction
  on property: develops from
  some values from: lamina anlage
definition: Lateral-most synaptic neuropil domain of the adult optic lobes, lying just beneath the compound eyes. It is composed of an array of repetitive cartridge-like units, each of which receives axons from specific sets of ommatidia in the compound eyes.
database_cross_reference: VFB:FBbt_00003708
has exact synonym: LA
has OBO namespace: fly_anatomy.ontology
has related synonym: La
id: FBbt:00003708
in subset: BrainName
in subset: cur

Axiom
annotated source: lamina
annotated property: definition
annotated target: Lateral-most synaptic neuropil domain of the adult optic lobes, lying just beneath the compound eyes. It is composed of an array of repetitive cartridge-like units, each of which receives axons from specific sets of ommatidia in the compound eyes.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0231227
database_cross_reference: VFB_vol:00003708

Axiom
annotated source: lamina
annotated property: hasExactSynonym
annotated target: LA
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

lamina monopolar neuron
type: Class
subclass of: FBbt_00007578
subclass of: FBbt_00110136
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00100206
subclass of: Restriction
  on property: overlaps
  some values from: optic cartridge
subclass of: Restriction
  on property: overlaps
  some values from: first optic chiasma
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053355
definition: Monopolar, intrinsic unicolumnar neuron of the adult optic lobe that has its soma in the cell body rind of the lamina and connects the lamina to the medulla (Fischbach and Dittrich, 1989). It has a single major projection that projects along one optic cartridge in the lamina, crosses the first optic chiasm and terminates in the same cartridge in the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: VFB:FBbt_00003718
has exact synonym: LMC
has exact synonym: lamina monopolar cell
has exact synonym: monopolar laminar cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003718
in subset: cur

Axiom
annotated source: lamina monopolar neuron
annotated property: definition
annotated target: Monopolar, intrinsic unicolumnar neuron of the adult optic lobe that has its soma in the cell body rind of the lamina and connects the lamina to the medulla (Fischbach and Dittrich, 1989). It has a single major projection that projects along one optic cartridge in the lamina, crosses the first optic chiasm and terminates in the same cartridge in the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410

lamina monopolar neuron L1
type: Class
subclass of: lamina monopolar neuron
subclass of: FBbt_00058208
subclass of: Restriction
  on property: electrically_synapsed_to
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053356
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R6
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: centrifugal neuron C3
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm3
IAO_0000028: L1
definition: Lamina monopolar neuron that has short collaterals projecting radially from the main projection in the lamina and arborization in medulla layers M1 and M5 (Fischbach and Dittrich, 1989; Kind et al., 2021). In the lamina, these short collaterals are strongly postsynaptic to the terminals of photoreceptors R1-6 (Rivera-Alba et al., 2011). In the medulla, it makes strong reciprocal synaptic connections with lamina monopolar cell L5 and centrifugal neuron C2, as well as substantial output synapses to C3, Mi1 and Tm3 cells (Takemura et al., 2013). It is also electrically synapsed to lamina monopolar neuron L2 (Joesch et al., 2010). It is a glutamatergic neuron (Gao et al., 2008; Takemura et al., 2011). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10089
database_cross_reference: VFB:FBbt_00003719
has exact synonym: L1
has exact synonym: monopolar laminar cell L1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003719
in subset: cur
comment: The neurotransmitter was assessed by labelling cells with a vGlut[OK371]-dVP16AD-GAL4 driver (FBti0129742) (Gao et al., 2008) or by single cell RT-PCR with specific primers (Takemura et al., 2011). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for L1 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (-/40), R2 (-/43), R3 (-/37), R4 (-/38), R5 (-/38), R6 (-/45), L2 (-/3), Lai (-/1), C3 (-/3) and Lawf (-/1) (Rivera-Alba et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013). Electrical connectivity was shown by dye labelling (Joesch et al., 2010).

Axiom
annotated source: lamina monopolar neuron L1
annotated property: IAO_0000028
annotated target: L1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L1
annotated property: definition
annotated target: Lamina monopolar neuron that has short collaterals projecting radially from the main projection in the lamina and arborization in medulla layers M1 and M5 (Fischbach and Dittrich, 1989; Kind et al., 2021). In the lamina, these short collaterals are strongly postsynaptic to the terminals of photoreceptors R1-6 (Rivera-Alba et al., 2011). In the medulla, it makes strong reciprocal synaptic connections with lamina monopolar cell L5 and centrifugal neuron C2, as well as substantial output synapses to C3, Mi1 and Tm3 cells (Takemura et al., 2013). It is also electrically synapsed to lamina monopolar neuron L2 (Joesch et al., 2010). It is a glutamatergic neuron (Gao et al., 2008; Takemura et al., 2011). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0212262
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina monopolar neuron L1
annotated property: hasExactSynonym
annotated target: L1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina monopolar neuron L2
type: Class
subclass of: lamina monopolar neuron
subclass of: FBbt_00058205
subclass of: Restriction
  on property: electrically_synapsed_to
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053357
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R6
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: columnar neuron T1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm4
IAO_0000028: L2
definition: A lamina monopolar neuron with short collaterals that project radially from the main projection in the lamina and that arborizes in medulla layer M2. In the lamina it receives strong input from photoreceptors R1-R6 (Rivera-Alba et al., 2011). It has both pre- and postsynaptic connections in medulla layer M2, with strong synaptic input coming from centrifugal neurons C2 and C3 (Takemura et al., 2013). It has a large number of presynaptic connections to lamina monopolar neuron L5, columnar neuron T1, and transmedullary neurons Tm1, Tm2 and Tm4 (Takemura et al., 2013). It is a cholinergic neuron (Takemura et al., 2011) and is electrically synapsed to lamina monopolar neuron L1 (Joesch et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10090
database_cross_reference: VFB:FBbt_00003720
has exact synonym: L2
has exact synonym: monopolar laminar cell L2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003720
in subset: cur
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for L2 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (1/46), R2 (1/45), R3 (-/39), R4 (-/41), R5 (-/39), R6 (-/47), L1 (3/-), L4 (10/7), L5 (1/-), Lai (-/1), C2 (-/3), C3 (-/5) and Lwf (-/7) (Rivera-Alba et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013). Note that for many of the output synapses in M2, Tm1 and Tm2 share the same sites (Takemura et al., 2008; Takemura et al., 2011). Electrical connectivity was shown by dye labelling (Joesch et al., 2010). The neurotransmitter was assessed by single cell RT-PCR measurement of choline acetyltransferase (FBgn0000303) expression (Takemura et al., 2011).

Axiom
annotated source: lamina monopolar neuron L2
annotated property: IAO_0000028
annotated target: L2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L2
annotated property: definition
annotated target: A lamina monopolar neuron with short collaterals that project radially from the main projection in the lamina and that arborizes in medulla layer M2. In the lamina it receives strong input from photoreceptors R1-R6 (Rivera-Alba et al., 2011). It has both pre- and postsynaptic connections in medulla layer M2, with strong synaptic input coming from centrifugal neurons C2 and C3 (Takemura et al., 2013). It has a large number of presynaptic connections to lamina monopolar neuron L5, columnar neuron T1, and transmedullary neurons Tm1, Tm2 and Tm4 (Takemura et al., 2013). It is a cholinergic neuron (Takemura et al., 2011) and is electrically synapsed to lamina monopolar neuron L1 (Joesch et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0212262
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina monopolar neuron L2
annotated property: hasExactSynonym
annotated target: L2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina monopolar neuron L3
type: Class
subclass of: lamina monopolar neuron
subclass of: FBbt_00058207
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053358
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: outer photoreceptor cell
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: inner photoreceptor cell
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi9
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm20
IAO_0000028: L3
definition: Lamina monopolar neuron with short spines that project to one side of the main projection as it extends through the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It terminates with an arborization in medulla layer M3 (Fischbach and Dittrich, 1989; Kind et al., 2021). In the lamina it is postsynaptic to the outer photoreceptors (R1-R6) (Rivera-Alba et al., 2011). It also receives input from the inner photoreceptors, partly in the first optic chiasm and partly in the medulla (Kind et al., 2021). It forms presynaptic terminals in medulla layer M3 (Takemura et al., 2008), with strong outputs to Mi9 and Tm20 (Takemura et al., 2013). It is a GABAergic neuron (Raghu et al., 2013). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10091
database_cross_reference: VFB:FBbt_00003721
has exact synonym: L3
has exact synonym: monopolar laminar cell L3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003721
in subset: cur
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for L3 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (-/11), R2 (-/10), R3 (-/4), R4 (-/8), R5 (-/6), R6 (-/12), L4 (-/1), L5 (1/-), Lai (-/10) and Lawf (-/17) (Rivera-Alba et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013). The neurotransmitter was assessed by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA (Raghu et al., 2013).

Axiom
annotated source: lamina monopolar neuron L3
annotated property: IAO_0000028
annotated target: L3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L3
annotated property: definition
annotated target: Lamina monopolar neuron with short spines that project to one side of the main projection as it extends through the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It terminates with an arborization in medulla layer M3 (Fischbach and Dittrich, 1989; Kind et al., 2021). In the lamina it is postsynaptic to the outer photoreceptors (R1-R6) (Rivera-Alba et al., 2011). It also receives input from the inner photoreceptors, partly in the first optic chiasm and partly in the medulla (Kind et al., 2021). It forms presynaptic terminals in medulla layer M3 (Takemura et al., 2008), with strong outputs to Mi9 and Tm20 (Takemura et al., 2013). It is a GABAergic neuron (Raghu et al., 2013). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0220286
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina monopolar neuron L3
annotated property: hasExactSynonym
annotated target: L3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina monopolar neuron L4
type: Class
subclass of: CL_0008061
subclass of: lamina monopolar neuron
subclass of: FBbt_00058205
subclass of: FBbt_00058207
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053359
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm2
IAO_0000028: L4
definition: A lamina monopolar neuron that arborizes in the proximal lamina, forms a spreading arbor in medulla layer M2 and a small terminal arbor in M4-M5 that penetrates adjacent columns (Fischbach and Dittrich, 1989; Takemura et al., 2008; Takemura et al., 2011). In the medulla it forms presynaptic terminals in both M2 and M4-M5 with transmedullary neuron Tm2; three L4 neurons, one from the parent column and two from the posterior ones contact the same Tm2 neuron (Takemura et al., 2008; Takemura et al., 2011). It seems to be capable of both cholinergic and GABAergic neurotransmission.
has alternative id: FBbt:00003723
has alternative id: FBbt:00003724
database_cross_reference: FlyBrain_NDB:10092
database_cross_reference: VFB:FBbt_00003722
has exact synonym: L4
has exact synonym: monopolar laminar cell L4
has exact synonym: monopolar laminar cell L4x
has exact synonym: monopolar laminar cell L4y
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003722
in subset: cur
comment: Note, Fischbach and Dittrich (1989) have this as arborizing in M4, but we follow the more detailed analysis of Takemura and colleagues (2008) who place the terminal arbor in M5. This difference may have to do with the different ways the two papers define L4. Note also that L4x and L4y are simply a way of referring to L4 collaterals from an adjacent cartridge in descriptions of synaptic connectivity (see Meinertzhagen and O'Neil, 1991) and are not separate neurons. Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008; Takemura et al., 2011). Takemura et al. (2011) and Davis et al. (2020) report the neurotransmitter to be acetylcholine as assessed by single cell RT-PCR measurement of choline acetyltransferase (FBgn0000303) expression and scRNAseq detection of both choline acetyltransferase and vesicular acetylcholine transporter (FBgn0270928). However, Raghu et al. (2013) report this neuron to be GABAergic as assessed by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA.

Axiom
annotated source: lamina monopolar neuron L4
annotated property: IAO_0000028
annotated target: L4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L4
annotated property: definition
annotated target: A lamina monopolar neuron that arborizes in the proximal lamina, forms a spreading arbor in medulla layer M2 and a small terminal arbor in M4-M5 that penetrates adjacent columns (Fischbach and Dittrich, 1989; Takemura et al., 2008; Takemura et al., 2011). In the medulla it forms presynaptic terminals in both M2 and M4-M5 with transmedullary neuron Tm2; three L4 neurons, one from the parent column and two from the posterior ones contact the same Tm2 neuron (Takemura et al., 2008; Takemura et al., 2011). It seems to be capable of both cholinergic and GABAergic neurotransmission.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0220286

Axiom
annotated source: lamina monopolar neuron L4
annotated property: hasExactSynonym
annotated target: L4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

Axiom
annotated source: lamina monopolar neuron L4
annotated property: hasExactSynonym
annotated target: monopolar laminar cell L4x
database_cross_reference: FlyBase:FBrf0054529

Axiom
annotated source: lamina monopolar neuron L4
annotated property: hasExactSynonym
annotated target: monopolar laminar cell L4y
database_cross_reference: FlyBase:FBrf0054529

lamina monopolar neuron L5
type: Class
subclass of: lamina monopolar neuron
subclass of: FBbt_00058205
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053360
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi4
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm3
IAO_0000028: L5
definition: A lamina monopolar neuron that hardly arborizes at all in the lamina, but forms a branched arborization in medulla layers M1 and M2 and a clump of terminals in M5. In the medulla, it forms strong reciprocal synaptic connections with monopolar lamina monopolar neuron L1 (Takemura et al., 2013). It also receives substantial input from L2 and C2 neurons and has many presynapses connecting to medullary intrinsic neurons Mi1 and Mi4, and to transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Davis et al., 2020). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10093
database_cross_reference: VFB:FBbt_00003725
has exact synonym: L5
has exact synonym: monopolar laminar cell L5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003725
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).

Axiom
annotated source: lamina monopolar neuron L5
annotated property: IAO_0000028
annotated target: L5
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L5
annotated property: definition
annotated target: A lamina monopolar neuron that hardly arborizes at all in the lamina, but forms a branched arborization in medulla layers M1 and M2 and a clump of terminals in M5. In the medulla, it forms strong reciprocal synaptic connections with monopolar lamina monopolar neuron L1 (Takemura et al., 2013). It also receives substantial input from L2 and C2 neurons and has many presynapses connecting to medullary intrinsic neurons Mi1 and Mi4, and to transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Davis et al., 2020). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina monopolar neuron L5
annotated property: hasExactSynonym
annotated target: L5
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T neuron
type: Class
subclass of: FBbt_00007578
subclass of: Restriction
  on property: overlaps
  some values from: second optic chiasma
definition: Intrinsic columnar neuron of the optic lobe that has its cell body in the posterior part of the optic lobe and a cell body fiber that bifurcates in the second optic chiasma (Fischbach and Dittrich, 1989). It has two branches, each targeting a different neuropil adjacent to the second optic chiasma (lobula, lobula plate and medulla) (Fischbach and Dittrich, 1989).
database_cross_reference: VFB:FBbt_00003726
has OBO namespace: fly_anatomy.ontology
has related synonym: T
id: FBbt:00003726
in subset: cur

Axiom
annotated source: T neuron
annotated property: definition
annotated target: Intrinsic columnar neuron of the optic lobe that has its cell body in the posterior part of the optic lobe and a cell body fiber that bifurcates in the second optic chiasma (Fischbach and Dittrich, 1989). It has two branches, each targeting a different neuropil adjacent to the second optic chiasma (lobula, lobula plate and medulla) (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410

columnar neuron T1
type: Class
subclass of: FBbt_00007578
subclass of: FBbt_00049542
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00100205
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052324
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina intrinsic neuron Lai
IAO_0000028: T1
definition: An intrinsic columnar neuron whose cell body lies in the cortex of the medulla. The fiber of the T1 cell body branches at the medulla surface to form a T-shaped linking fiber between a bush-like arborization in the distal part of a medulla column (M1 and M2), and a bundle of climbing fibers in the equivalent column of the lamina (Fischbach and Dittrich, 1989). Synaptic connections in the lamina are exclusively postsynaptic and include a large number of connections from lamina intrinsic (amacrine) neurons (Meinertzhagen and O'Neil, 1991; Rivera-Alba et al., 2011). In the medulla, it is strongly synapsed by centrifugal neuron C3 in medulla layer M2 and lamina monopolar neuron L2 (Takemura et al., 2008; Takemura et al., 2013). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10115
database_cross_reference: VFB:FBbt_00003727
has exact synonym: T neuron T1
has exact synonym: T1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003727
in subset: cur
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for T1 (presynaptic/postsynaptic) in a single lamina cartridge for each cell type was the following: R2 (-/2), R3 (-/2), R4 (-/2), Lai (-/54), C3 (-/1) and Lawf (-/1) (Rivera-Alba et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013).

Axiom
annotated source: columnar neuron T1
annotated property: IAO_0000028
annotated target: T1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: columnar neuron T1
annotated property: definition
annotated target: An intrinsic columnar neuron whose cell body lies in the cortex of the medulla. The fiber of the T1 cell body branches at the medulla surface to form a T-shaped linking fiber between a bush-like arborization in the distal part of a medulla column (M1 and M2), and a bundle of climbing fibers in the equivalent column of the lamina (Fischbach and Dittrich, 1989). Synaptic connections in the lamina are exclusively postsynaptic and include a large number of connections from lamina intrinsic (amacrine) neurons (Meinertzhagen and O'Neil, 1991; Rivera-Alba et al., 2011). In the medulla, it is strongly synapsed by centrifugal neuron C3 in medulla layer M2 and lamina monopolar neuron L2 (Takemura et al., 2008; Takemura et al., 2013). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: columnar neuron T1
annotated property: hasExactSynonym
annotated target: T1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T4 neuron
type: Class
subclass of: T neuron
subclass of: FBbt_00047096
subclass of: FBbt_00058205
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00051036
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052257
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: FBbt_00048345
IAO_0000028: T4
definition: T neuron with its cell body posterior to the lobula plate and a cell body fiber that projects through the lobula plate and via the second optic chiasma, with little or no arborization, to medulla layer 10 (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It forms a fine arborization in medulla layers M9 and M10 and its axon then doubles back across the second optic chiasma to form bleb-type arborizations in a single layer of the lobula plate (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T4 (and T5) neurons (Mora et al., 2018).
database_cross_reference: VFB:FBbt_00003731
has exact synonym: T neuron T4
has exact synonym: T4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003731
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. The neurotransmitter was assessed with a split-GAL4 strategy using a Chat-DBD allele (FBal0198074) (Mauss et al., 2014) and single-cell transcript profiling (Shinomiya et al., 2014).

Axiom
annotated source: T4 neuron
annotated property: IAO_0000028
annotated target: T4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T4 neuron
annotated property: definition
annotated target: T neuron with its cell body posterior to the lobula plate and a cell body fiber that projects through the lobula plate and via the second optic chiasma, with little or no arborization, to medulla layer 10 (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It forms a fine arborization in medulla layers M9 and M10 and its axon then doubles back across the second optic chiasma to form bleb-type arborizations in a single layer of the lobula plate (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T4 (and T5) neurons (Mora et al., 2018).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0224060
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0238554
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: T4 neuron
annotated property: hasExactSynonym
annotated target: T4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T5 neuron
type: Class
subclass of: T neuron
subclass of: FBbt_00047096
subclass of: FBbt_00058205
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult lobula plate
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052258
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: FBbt_00048345
IAO_0000028: T5
definition: T neuron with its cell body in the lobula plate cell body rind and a cell body fiber that projects through the lobula plate and via the second optic chiasma, with little or no arborization, to lobula layer 1 (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It forms a fine arborization in lobula layer 1, then its axon doubles back across the second optic chiasma to form bleb-type arborizations in a single layer of the lobula plate (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T5 (and T4) neurons (Mora et al., 2018).
database_cross_reference: VFB:FBbt_00003736
has exact synonym: T neuron T5
has exact synonym: T5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003736
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. The neurotransmitter was assessed with a split-GAL4 strategy using a Chat-DBD allele (FBal0198074) (Mauss et al., 2014) and single-cell transcript profiling (Shinomiya et al., 2014). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014).

Axiom
annotated source: T5 neuron
annotated property: IAO_0000028
annotated target: T5
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T5 neuron
annotated property: definition
annotated target: T neuron with its cell body in the lobula plate cell body rind and a cell body fiber that projects through the lobula plate and via the second optic chiasma, with little or no arborization, to lobula layer 1 (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It forms a fine arborization in lobula layer 1, then its axon doubles back across the second optic chiasma to form bleb-type arborizations in a single layer of the lobula plate (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T5 (and T4) neurons (Mora et al., 2018).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0224060
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0238554
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: T5 neuron
annotated property: hasExactSynonym
annotated target: T5
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina wide-field 1 neuron
type: Class
subclass of: FBbt_00059323
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L3
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina intrinsic neuron Lai
IAO_0000028: Lawf1
definition: A lamina wide-field neuron that has a main projection that ascends via the first optic chiasm into the lamina where it is restricted to a single column for most of its length before making wide-field arborizations in the distal lamina. These neurons also arborize on the distal surface of the medulla in a circular field of about 20 columns. Several linking fibers from this arborization descend into M4 where they form a wide arborization field covering about 30-40 columns (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In the lamina, it forms numerous presynaptic connections to lamina monopolar neuron L3 and lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011).
database_cross_reference: FlyBrain_NDB:10094
database_cross_reference: VFB:FBbt_00003741
has exact synonym: LaWF1
has exact synonym: Lawf
has exact synonym: Lawf1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003741
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The identification of dendrites and axons was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP} - FBtp0021447) or a UAS-tau (P{UAS-tau-lacZ.O} - FBtp0010033) reporter, respectively (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for Lawf (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (1/1), R2 (3/-), R3 (1/-), R6 (1/-), L1 (1/-), L2 (7/-), L3 (17/-), L5 (1/-), Lai (24/-), T1 (1/-), C2 (3/-), C3 (2/-), Lawf collaterals (5) and epithelial glia (6/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: IAO_0000028
annotated target: Lawf1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: definition
annotated target: A lamina wide-field neuron that has a main projection that ascends via the first optic chiasm into the lamina where it is restricted to a single column for most of its length before making wide-field arborizations in the distal lamina. These neurons also arborize on the distal surface of the medulla in a circular field of about 20 columns. Several linking fibers from this arborization descend into M4 where they form a wide arborization field covering about 30-40 columns (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In the lamina, it forms numerous presynaptic connections to lamina monopolar neuron L3 and lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: hasExactSynonym
annotated target: LaWF1
database_cross_reference: FlyBase:FBrf0222324

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: hasExactSynonym
annotated target: Lawf
database_cross_reference: FlyBrain_NDB:10094

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: hasExactSynonym
annotated target: Lawf1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

optic lobe centrifugal columnar neuron
type: Class
subclass of: FBbt_00007578
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00100205
subclass of: Restriction
  on property: overlaps
  some values from: first optic chiasma
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: optic cartridge
definition: Columnar neuron whose soma lies in the cortex between the medulla and the lobula plate that extends through a single column of the medulla and lamina.
database_cross_reference: VFB:FBbt_00003742
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003742
in subset: cur

Axiom
annotated source: optic lobe centrifugal columnar neuron
annotated property: definition
annotated target: Columnar neuron whose soma lies in the cortex between the medulla and the lobula plate that extends through a single column of the medulla and lamina.
database_cross_reference: FlyBase:FBrf0049410

centrifugal neuron C2
type: Class
subclass of: optic lobe centrifugal columnar neuron
subclass of: FBbt_00058207
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi1
IAO_0000028: C2
definition: Adult centrifugal neuron with arborizations in the medulla layers M1, M5/M6, M8 and M10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). In the medulla, it makes reciprocal connections to lamina monopolar neuron L1, and is presynaptic to L2 and L5, as well as medullary intrinsic neuron Mi1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10079
database_cross_reference: VFB:FBbt_00003743
has exact synonym: C2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003743
in subset: cur
comment: Pre- versus postsynaptic innervation in the proximal medulla was inferred by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).

Axiom
annotated source: centrifugal neuron C2
annotated property: IAO_0000028
annotated target: C2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: centrifugal neuron C2
annotated property: definition
annotated target: Adult centrifugal neuron with arborizations in the medulla layers M1, M5/M6, M8 and M10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). In the medulla, it makes reciprocal connections to lamina monopolar neuron L1, and is presynaptic to L2 and L5, as well as medullary intrinsic neuron Mi1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0210635
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: centrifugal neuron C2
annotated property: hasExactSynonym
annotated target: C2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

centrifugal neuron C3
type: Class
subclass of: optic lobe centrifugal columnar neuron
subclass of: FBbt_00058207
subclass of: FBbt_00110137
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: columnar neuron T1
IAO_0000028: C3
definition: Adult centrifugal neuron with arborizations in medulla layers M1-2, M5, and M9-10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It forms presynapses and postsynapses in the lamina (Morante and Desplan, 2008; Rivera-Alba et al., 2011). In the medulla it is strongly presynaptic to monopolar lamina neuron L2 and columnar neuron T1, and strongly postsynaptic to L1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10080
database_cross_reference: VFB:FBbt_00003744
has exact synonym: C3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003744
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The identification of dendrites was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP} - FBtp0021447) reporter (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).

Axiom
annotated source: centrifugal neuron C3
annotated property: IAO_0000028
annotated target: C3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: centrifugal neuron C3
annotated property: definition
annotated target: Adult centrifugal neuron with arborizations in medulla layers M1-2, M5, and M9-10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It forms presynapses and postsynapses in the lamina (Morante and Desplan, 2008; Rivera-Alba et al., 2011). In the medulla it is strongly presynaptic to monopolar lamina neuron L2 and columnar neuron T1, and strongly postsynaptic to L1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0210635
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: centrifugal neuron C3
annotated property: hasExactSynonym
annotated target: C3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina tangential neuron
type: Class
subclass of: FBbt_00007579
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lamina
definition: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more layers of the lamina.
database_cross_reference: VFB:FBbt_00003745
has OBO namespace: fly_anatomy.ontology
has related synonym: Lat
id: FBbt:00003745
in subset: cur

Axiom
annotated source: lamina tangential neuron
annotated property: definition
annotated target: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more layers of the lamina.
database_cross_reference: FlyBase:FBrf0049410

lamina intrinsic neuron Lai
type: Class
subclass of: adult optic lobe neuron
subclass of: lamina tangential neuron
subclass of: optic lobe amacrine neuron
subclass of: FBbt_00049542
subclass of: FBbt_00058208
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00100206
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052316
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina wide-field 1 neuron
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R6
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: columnar neuron T1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: FBbt_00100513
subclass of: Restriction
  on property: synapses restricted to region
  some values from: lamina
IAO_0000028: Lai
definition: Intrinsic amacrine neuron of the lamina with arborizations spanning the proximal and distal lamina, whose cell body lies proximal to the lamina (Fischbach and Dittrich, 1989; Meinertzhagen and Sorra, 2001). It has extensive arborizations and forms a substantial number of presynaptic terminals with columnar neuron T1 and epithelial glia (Rivera-Alba et al., 2011). It receives strong input from each of photoreceptors R1-R6, and from lamina wide-field cells (Rivera-Alba et al., 2011). It is a glutamatergic neuron (Davis et al., 2020). There are approximately 210 of these cells on each side (Nern et al., 2025).
has broad synonym: Am
has broad synonym: amacrine cell
database_cross_reference: VFB:FBbt_00003746
has exact synonym: Lai
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003746
in subset: cur
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for Lai (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (-/36), R2 (1/39), R3 (-/39), R4 (2/37), R5 (2/35), R6 (-/40), L1 (1/-), L2 (1/-), L3 (10/-), L4 (4/2), L5 (4/-), Lai (1), T1 (54/1), C2 (1/5), C3 (1/9), Lawf (-/24) and epithelial glia (87/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: IAO_0000028
annotated target: Lai
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: definition
annotated target: Intrinsic amacrine neuron of the lamina with arborizations spanning the proximal and distal lamina, whose cell body lies proximal to the lamina (Fischbach and Dittrich, 1989; Meinertzhagen and Sorra, 2001). It has extensive arborizations and forms a substantial number of presynaptic terminals with columnar neuron T1 and epithelial glia (Rivera-Alba et al., 2011). It receives strong input from each of photoreceptors R1-R6, and from lamina wide-field cells (Rivera-Alba et al., 2011). It is a glutamatergic neuron (Davis et al., 2020). There are approximately 210 of these cells on each side (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0159582
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: hasBroadSynonym
annotated target: Am
database_cross_reference: FlyBase:FBrf0159582

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: hasBroadSynonym
annotated target: amacrine cell
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: hasExactSynonym
annotated target: Lai
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

optic cartridge
type: Class
subclass of: FBbt_00040069
subclass of: Restriction
  on property: part of
  some values from: lamina
definition: Segment (column) of the lamina defined by the distal-proximal (eye to central brain) projections of photoreceptor cells of a single ommatidium.
database_cross_reference: VFB:FBbt_00003747
has OBO namespace: fly_anatomy.ontology
has related synonym: cartridge
has related synonym: lamina cartridge
id: FBbt:00003747
in subset: cur

Axiom
annotated source: optic cartridge
annotated property: definition
annotated target: Segment (column) of the lamina defined by the distal-proximal (eye to central brain) projections of photoreceptor cells of a single ommatidium.
database_cross_reference: FlyBase:FBrf0049410

medulla
type: Class
subclass of: FBbt_00025991
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
subclass of: Restriction
  on property: develops from
  some values from: medulla anlage
definition: The second optic neuropil, sandwiched between the lamina and the lobula complex. It is divided into 10 layers: 1-6 make up the outer (distal) medulla, the seventh (or serpentine) layer exhibits a distinct architecture and layers 8-10 make up the inner (proximal) medulla (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00003748
has exact synonym: ME
has exact synonym: Med
has exact synonym: optic medulla
has OBO namespace: fly_anatomy.ontology
has related synonym: m
id: FBbt:00003748
in subset: BrainName
in subset: FB gloss
in subset: cur
comment: Nern et al. (2025) - FBrf0262545 say distal is M1-5 and M6-7 is central medulla.

Axiom
annotated source: medulla
annotated property: definition
annotated target: The second optic neuropil, sandwiched between the lamina and the lobula complex. It is divided into 10 layers: 1-6 make up the outer (distal) medulla, the seventh (or serpentine) layer exhibits a distinct architecture and layers 8-10 make up the inner (proximal) medulla (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0231227
database_cross_reference: VFB_vol:00003748

Axiom
annotated source: medulla
annotated property: hasExactSynonym
annotated target: ME
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: medulla
annotated property: hasExactSynonym
annotated target: Med
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: medulla
annotated property: hasExactSynonym
annotated target: optic medulla
database_cross_reference: FlyBase:FBrf0212889

outer medulla
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045001
definition: Layers 1-6 of the medulla.
has alternative id: FBbt:00040025
database_cross_reference: VFB:FBbt_00003749
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003749
in subset: BrainName
in subset: cur

Axiom
annotated source: outer medulla
annotated property: definition
annotated target: Layers 1-6 of the medulla.
database_cross_reference: FlyBase:FBrf0224194

medulla layer M1
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Distal-most layer of the medulla. It is defined by the distal extent of the distal lamina monopolar neuron L1 arborization (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040026
database_cross_reference: VFB:FBbt_00003750
has exact synonym: stratum M1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003750
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M1
annotated property: definition
annotated target: Distal-most layer of the medulla. It is defined by the distal extent of the distal lamina monopolar neuron L1 arborization (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M1
annotated property: hasExactSynonym
annotated target: stratum M1
database_cross_reference: FlyBase:FBrf0205531

medulla layer M2
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Second most lateral layer of the medulla. It is defined by the distal extent of the distal lamina monopolar neuron L2 arborization (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040027
database_cross_reference: VFB:FBbt_00003751
has exact synonym: L2 layer
has exact synonym: layer M2
has exact synonym: medulla layer 2
has exact synonym: stratum M2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003751
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M2
annotated property: definition
annotated target: Second most lateral layer of the medulla. It is defined by the distal extent of the distal lamina monopolar neuron L2 arborization (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M2
annotated property: hasExactSynonym
annotated target: L2 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M2
annotated property: hasExactSynonym
annotated target: layer M2
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M2
annotated property: hasExactSynonym
annotated target: stratum M2
database_cross_reference: FlyBase:FBrf0205531

medulla layer M3
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Third most lateral layer of the medulla. It is defined by the proximal border of the lamina monopolar neuron L2 arborization to that of the lamina neuron L3 terminal (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040028
database_cross_reference: VFB:FBbt_00003752
has exact synonym: L3 layer
has exact synonym: medulla layer 3
has exact synonym: stratum M3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003752
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M3
annotated property: definition
annotated target: Third most lateral layer of the medulla. It is defined by the proximal border of the lamina monopolar neuron L2 arborization to that of the lamina neuron L3 terminal (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M3
annotated property: hasExactSynonym
annotated target: L3 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M3
annotated property: hasExactSynonym
annotated target: stratum M3
database_cross_reference: FlyBase:FBrf0205531

medulla layer M4
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Fourth most lateral layer of the medulla. It corresponds to the narrow layer between the proximal end of lamina neuron L3 and the distal border of lamina neuron L1's proximal arborization (Takemura et al., 2008).
has alternative id: FBbt:00040029
database_cross_reference: VFB:FBbt_00003753
has exact synonym: L4 layer
has exact synonym: medulla layer 4
has exact synonym: stratum M4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003753
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. We use the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M4
annotated property: definition
annotated target: Fourth most lateral layer of the medulla. It corresponds to the narrow layer between the proximal end of lamina neuron L3 and the distal border of lamina neuron L1's proximal arborization (Takemura et al., 2008).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M4
annotated property: hasExactSynonym
annotated target: L4 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M4
annotated property: hasExactSynonym
annotated target: stratum M4
database_cross_reference: FlyBase:FBrf0205531

medulla layer M5
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Fifth most lateral layer of the medulla. It is defined by the lamina neuron L1's proximal arborization and contains the proximal lamina neuron L5 terminal (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040030
database_cross_reference: VFB:FBbt_00003754
has exact synonym: medulla layer 5
has exact synonym: proximal L1 layer
has exact synonym: stratum M5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003754
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M5
annotated property: definition
annotated target: Fifth most lateral layer of the medulla. It is defined by the lamina neuron L1's proximal arborization and contains the proximal lamina neuron L5 terminal (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M5
annotated property: hasExactSynonym
annotated target: proximal L1 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M5
annotated property: hasExactSynonym
annotated target: stratum M5
database_cross_reference: FlyBase:FBrf0205531

medulla layer M6
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Sixth most lateral layer of the medulla, immediately lateral to the serpentine layer. It lies between the lamina neuron L1's arborization and the serpentine layer (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040031
database_cross_reference: VFB:FBbt_00003755
has exact synonym: R7 layer
has exact synonym: medulla layer 6
has exact synonym: stratum M6
has OBO namespace: fly_anatomy.ontology
has related synonym: R7 recipient layer
id: FBbt:00003755
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M6
annotated property: definition
annotated target: Sixth most lateral layer of the medulla, immediately lateral to the serpentine layer. It lies between the lamina neuron L1's arborization and the serpentine layer (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M6
annotated property: hasExactSynonym
annotated target: R7 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M6
annotated property: hasExactSynonym
annotated target: stratum M6
database_cross_reference: FlyBase:FBrf0205531

Axiom
annotated source: medulla layer M6
annotated property: hasRelatedSynonym
annotated target: R7 recipient layer
database_cross_reference: FlyBase:FBrf0209317

medulla serpentine layer
type: Class
subclass of: FBbt_00048343
definition: A major layer of extensive tangential fibers in the medulla, many of which project via the posterior optic commissure to the opposite medulla. It is the 7th most lateral layer of the medulla.
database_cross_reference: VFB:FBbt_00003756
has exact synonym: SPL
has exact synonym: medulla layer 7
has OBO namespace: fly_anatomy.ontology
has related synonym: medulla layer M7
id: FBbt:00003756
in subset: BrainName
in subset: cur

Axiom
annotated source: medulla serpentine layer
annotated property: definition
annotated target: A major layer of extensive tangential fibers in the medulla, many of which project via the posterior optic commissure to the opposite medulla. It is the 7th most lateral layer of the medulla.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0065419
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla serpentine layer
annotated property: hasExactSynonym
annotated target: SPL
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

inner medulla
type: Class
subclass of: FBbt_00048343
definition: Layers 8-10 of the medulla.
database_cross_reference: VFB:FBbt_00003757
has exact synonym: MEI
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003757
in subset: BrainName
in subset: cur

Axiom
annotated source: inner medulla
annotated property: definition
annotated target: Layers 8-10 of the medulla.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: inner medulla
annotated property: hasExactSynonym
annotated target: MEI
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

medulla layer M8
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: inner medulla
definition: Lateral-most layer of the inner medulla, immediately medial to the serpentine layer.
has alternative id: FBbt:00040022
database_cross_reference: VFB:FBbt_00003758
has exact synonym: medulla layer 8
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003758
in subset: cur

Axiom
annotated source: medulla layer M8
annotated property: definition
annotated target: Lateral-most layer of the inner medulla, immediately medial to the serpentine layer.
database_cross_reference: FlyBase:FBrf0224194

medulla layer M9
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: inner medulla
definition: Middle layer of the inner medulla.
has alternative id: FBbt:00040023
database_cross_reference: VFB:FBbt_00003759
has exact synonym: medulla layer 9
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003759
in subset: cur

Axiom
annotated source: medulla layer M9
annotated property: definition
annotated target: Middle layer of the inner medulla.
database_cross_reference: FlyBase:FBrf0224194

medulla layer M10
type: Class
subclass of: FBbt_00048343
subclass of: Restriction
  on property: part of
  some values from: inner medulla
definition: Inner-most layer of the medulla. Practically it is defined by the height of the T4 neuron terminal arborizations.
has alternative id: FBbt:00040024
database_cross_reference: VFB:FBbt_00003760
has exact synonym: T4 layer
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003760
in subset: cur

Axiom
annotated source: medulla layer M10
annotated property: definition
annotated target: Inner-most layer of the medulla. Practically it is defined by the height of the T4 neuron terminal arborizations.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M10
annotated property: hasExactSynonym
annotated target: T4 layer
database_cross_reference: FlyBase:FBrf0049410

distal medullary amacrine neuron
type: Class
subclass of: adult optic lobe neuron
subclass of: optic lobe amacrine neuron
subclass of: FBbt_00053385
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00100205
IAO_0000028: Dm
definition: An amacrine neuron that is intrinsic to the medulla, whose soma is located in the cortex of the medulla and that branches and arborizes in the distal medulla. These neurons project through the distal surface of the medulla, to form wide (sometimes very wide) terminal arborizations mainly or completely restricted to a single layer of the medulla.
database_cross_reference: VFB:FBbt_00003767
has exact synonym: Dm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003767
in subset: cur

Axiom
annotated source: distal medullary amacrine neuron
annotated property: definition
annotated target: An amacrine neuron that is intrinsic to the medulla, whose soma is located in the cortex of the medulla and that branches and arborizes in the distal medulla. These neurons project through the distal surface of the medulla, to form wide (sometimes very wide) terminal arborizations mainly or completely restricted to a single layer of the medulla.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: distal medullary amacrine neuron
annotated property: hasExactSynonym
annotated target: Dm
has synonym type: VFB SYMBOL

distal medullary amacrine neuron Dm3
type: Class
subclass of: distal medullary amacrine neuron
subclass of: FBbt_00049542
subclass of: FBbt_00058208
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052310
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: FBbt_00111267
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: FBbt_00111267
IAO_0000028: Dm3
definition: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. It projects asymmetrically along layers M2 and M3A forming mixed morphology arborizations (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). The arborization is proximal to that of Dm15 in M2 and distal to Dm4, Dm12 and Dm20 in M3B. Its arbor has a distinct narrow and elongated shape, covering one column wide and 10 columns long. The arbors overlap significantly between cells, aligning with rows of medulla columns, and extending in one of two orthogonal orientations. It is a glutamatergic neuron (Raghu and Borst, 2011). There are two subtypes with different dendrite orientation, synaptic partners and gene expression (Ozel et al., 2021).
database_cross_reference: FlyBrain_NDB:10083
database_cross_reference: VFB:FBbt_00003770
has exact synonym: Dm3
has exact synonym: Dm3 line amacrine cell
has exact synonym: Dm3 line amacrine neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003770
in subset: cur
comment: The neurotransmitter was assessed by labelling cells with a vGlut[CNSIII]-GAL4 driver (FBti0129148) (Raghu and Borst, 2011). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: IAO_0000028
annotated target: Dm3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. It projects asymmetrically along layers M2 and M3A forming mixed morphology arborizations (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). The arborization is proximal to that of Dm15 in M2 and distal to Dm4, Dm12 and Dm20 in M3B. Its arbor has a distinct narrow and elongated shape, covering one column wide and 10 columns long. The arbors overlap significantly between cells, aligning with rows of medulla columns, and extending in one of two orthogonal orientations. It is a glutamatergic neuron (Raghu and Borst, 2011). There are two subtypes with different dendrite orientation, synaptic partners and gene expression (Ozel et al., 2021).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213690
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: hasExactSynonym
annotated target: Dm3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: hasExactSynonym
annotated target: Dm3 line amacrine cell
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: hasExactSynonym
annotated target: Dm3 line amacrine neuron
database_cross_reference: FlyBase:FBrf0262545

medulla intrinsic columnar neuron
type: Class
equivalent class: Class
  intersection of: FBbt_00007578
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: medulla
subclass of: FBbt_00007578
subclass of: FBbt_00053385
subclass of: FBbt_00111640
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00100205
IAO_0000028: Mi
definition: A columnar neuron that is intrinsic to the medulla, connecting distal and proximal layers (Fischbach and Dittrich, 1989; Kind et al., 2021). It has its soma in the cell body rind of the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: VFB:FBbt_00003775
has exact synonym: Mi
has exact synonym: medulla intrinsic cell
has exact synonym: medullary intrinsic columnar neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003775
in subset: cur

Axiom
annotated source: medulla intrinsic columnar neuron
annotated property: IAO_0000028
annotated target: Mi
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: medulla intrinsic columnar neuron
annotated property: definition
annotated target: A columnar neuron that is intrinsic to the medulla, connecting distal and proximal layers (Fischbach and Dittrich, 1989; Kind et al., 2021). It has its soma in the cell body rind of the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla intrinsic columnar neuron
annotated property: hasExactSynonym
annotated target: Mi
database_cross_reference: FlyBase:FBrf0252485
has synonym type: VFB SYMBOL

Axiom
annotated source: medulla intrinsic columnar neuron
annotated property: hasExactSynonym
annotated target: medulla intrinsic cell
database_cross_reference: FlyBase:FBrf0252485

medulla intrinsic neuron Mi1
type: Class
subclass of: medulla intrinsic columnar neuron
subclass of: FBbt_00049541
subclass of: FBbt_00058205
subclass of: FBbt_00110136
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052317
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M10
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T4 neuron
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm3
IAO_0000028: Mi1
definition: Unicolumnar medullary intrinsic neuron with bushy, fine arborizations in medulla layers M1, M5 and M9-10 (Fischbach and Dittrich, 1989; Kind et al., 2021). The projection of this neuron branches at the inner-face of the medulla to form two to three varicose recurrent terminal specializations that extend back up to the inner border of layer M8 (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In central (non-dorsal margin) columns it receives input from an R8 photoreceptor cell, but connections are substantially weaker in dorsal margin columns (Kind et al., 2021). Pre-synaptic terminals are present mainly in medulla layers M9-M10, but also in all other layers where neurites extend laterally (Pankova and Borst, 2017). It receives input from lamina monopolar neurons L1 and L5 and centrifugal neuron C2 (Takemura et al., 2013). It outputs to T4 neurons and transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Hasegawa et al., 2011; Pankova and Borst, 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10097
database_cross_reference: VFB:FBbt_00003776
has exact synonym: Mi1
has exact synonym: medullary intrinsic neuron 1
has exact synonym: medullary intrinsic neuron Mi1
has OBO namespace: fly_anatomy.ontology
has related synonym: Sut
has related synonym: small field unilateral tristratified neuron
id: FBbt:00003776
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The neurotransmitter was assessed by labelling cells with an anti-ChAT antibody (Hasegawa et al., 2011). The morphology of the terminals was judged from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity and morphology in the medulla were assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013).

Axiom
annotated source: medulla intrinsic neuron Mi1
annotated property: IAO_0000028
annotated target: Mi1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: medulla intrinsic neuron Mi1
annotated property: definition
annotated target: Unicolumnar medullary intrinsic neuron with bushy, fine arborizations in medulla layers M1, M5 and M9-10 (Fischbach and Dittrich, 1989; Kind et al., 2021). The projection of this neuron branches at the inner-face of the medulla to form two to three varicose recurrent terminal specializations that extend back up to the inner border of layer M8 (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In central (non-dorsal margin) columns it receives input from an R8 photoreceptor cell, but connections are substantially weaker in dorsal margin columns (Kind et al., 2021). Pre-synaptic terminals are present mainly in medulla layers M9-M10, but also in all other layers where neurites extend laterally (Pankova and Borst, 2017). It receives input from lamina monopolar neurons L1 and L5 and centrifugal neuron C2 (Takemura et al., 2013). It outputs to T4 neurons and transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Hasegawa et al., 2011; Pankova and Borst, 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213020
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0235353
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: medulla intrinsic neuron Mi1
annotated property: hasExactSynonym
annotated target: Mi1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

medulla intrinsic neuron Mi4
type: Class
subclass of: medulla intrinsic columnar neuron
subclass of: FBbt_00049542
subclass of: FBbt_00058207
subclass of: FBbt_00110136
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052319
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M8
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R8
IAO_0000028: Mi4
definition: Medulla intrinsic narrow field neuron with both fine and bleb-type arborizations in medulla layers M1, M2, M3 and M8, but with only fine arborizations in medulla layers M4 and M5, and only bleb-type arborizations in medulla layer M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). It receives input from the lamina monopolar neuron L5 and photoreceptor R8 (Takemura et al., 2013). It is a GABAergic neuron (Takemura et al., 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10103
database_cross_reference: VFB:FBbt_00003779
has exact synonym: Mi4
has exact synonym: medullary intrinsic neuron Mi4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003779
in subset: cur
comment: Raghu and Borst (2011) identified this as glutamatergic using a vGlut[CNSIII]-GAL4 driver (FBti0129148), but vGlut antibody staining performed by Takemura et al. (2017) was not strong compared to neighboring cells, whereas GAD1 staining was strong. Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013). Kind et al. (2020) say that it is not contacted by R7/R8 in the DRA, but not clear whether Mi4 is present in the DRA.

Axiom
annotated source: medulla intrinsic neuron Mi4
annotated property: IAO_0000028
annotated target: Mi4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: medulla intrinsic neuron Mi4
annotated property: definition
annotated target: Medulla intrinsic narrow field neuron with both fine and bleb-type arborizations in medulla layers M1, M2, M3 and M8, but with only fine arborizations in medulla layers M4 and M5, and only bleb-type arborizations in medulla layer M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). It receives input from the lamina monopolar neuron L5 and photoreceptor R8 (Takemura et al., 2013). It is a GABAergic neuron (Takemura et al., 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213690
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: medulla intrinsic neuron Mi4
annotated property: hasExactSynonym
annotated target: Mi4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

medulla intrinsic neuron Mi9
type: Class
subclass of: medulla intrinsic columnar neuron
subclass of: FBbt_00049542
subclass of: FBbt_00058208
subclass of: FBbt_00110136
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052320
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M10
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L3
IAO_0000028: Mi9
definition: Medulla intrinsic narrow field neuron with a bushy mix of bleb-type and fine terminal arborization in layers M2, M3 and M4 and in the lower medulla layers M9-M10 (Fischbach and Dittrich, 1989; Kind et al., 2021). It establishes pre- and post-synaptic connections in both the inner and outer medulla layers (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). It receives input from lamina monopolar neuron L3 (Takemura et al., 2013). It is glutamatergic (Takemura et al., 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10108
database_cross_reference: VFB:FBbt_00003784
has exact synonym: Mi9
has exact synonym: medullary intrinsic neuron Mi9
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003784
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The identification of dendrites and axons was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP} - FBtp0021447) or a UAS-tau (P{UAS-tau-lacZ.O} - FBtp0010033) reporter, respectively (Morante and Desplan, 2008). Connectivity in the medulla was extrapolated from serial EM from 7 columns (Takemura et al., 2013).

Axiom
annotated source: medulla intrinsic neuron Mi9
annotated property: IAO_0000028
annotated target: Mi9
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: medulla intrinsic neuron Mi9
annotated property: definition
annotated target: Medulla intrinsic narrow field neuron with a bushy mix of bleb-type and fine terminal arborization in layers M2, M3 and M4 and in the lower medulla layers M9-M10 (Fischbach and Dittrich, 1989; Kind et al., 2021). It establishes pre- and post-synaptic connections in both the inner and outer medulla layers (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). It receives input from lamina monopolar neuron L3 (Takemura et al., 2013). It is glutamatergic (Takemura et al., 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0235606
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: medulla intrinsic neuron Mi9
annotated property: hasExactSynonym
annotated target: Mi9
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron
type: Class
subclass of: FBbt_00007578
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0000634
subclass of: Restriction
  on property: has soma location
  some values from: FBbt_00100205
subclass of: Restriction
  on property: fasciculates with
  some values from: second optic chiasma
subclass of: Restriction
  on property: overlaps
  some values from: medulla
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula
IAO_0000028: Tm
definition: An intrinsic columnar neuron of the optic lobe whose cell body lies in the distal cortex of the medulla and that projects through the medulla and optic chiasm into the lobula. All neurons arborize in the lobula and most, but not all, in the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: VFB:FBbt_00003788
has exact synonym: Tm
has exact synonym: Tm neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003788
in subset: cur

Axiom
annotated source: transmedullary neuron
annotated property: IAO_0000028
annotated target: Tm
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron
annotated property: definition
annotated target: An intrinsic columnar neuron of the optic lobe whose cell body lies in the distal cortex of the medulla and that projects through the medulla and optic chiasm into the lobula. All neurons arborize in the lobula and most, but not all, in the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652

Axiom
annotated source: transmedullary neuron
annotated property: hasExactSynonym
annotated target: Tm
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm1
type: Class
subclass of: FBbt_00013789
subclass of: FBbt_00049541
subclass of: FBbt_00058205
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052325
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T5 neuron
IAO_0000028: Tm1
definition: Transmedullary narrow field neuron that terminates in lobula layer 1 with a bleb-type terminal arborization and that has fine arborizations in medulla layer M2 and bleb-type arborizations in M3 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). In the medulla, it receives strong synaptic input from lamina monopolar neuron L2 (Takemura et al., 2011; Takemura et al., 2013). It outputs onto T5 neurons (Shinomiya et al., 2019). It is a cholinergic neuron (Varija Raghu et al., 2011; Shinomiya et al., 2014). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10132
database_cross_reference: VFB:FBbt_00003789
has exact synonym: Tm1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003789
in subset: cur
comment: The neurotransmitter was assessed by co-labelling cells with a P{Cha-GAL4.7.4} driver (FBtp0014830) and an anti-ChAT antibody (Varija Raghu et al., 2011; Shinomiya et al., 2014). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014). Connectivity in the entire optic lobe was also assessed by EM (Shinomiya et al., 2019).

Axiom
annotated source: transmedullary neuron Tm1
annotated property: IAO_0000028
annotated target: Tm1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm1
annotated property: definition
annotated target: Transmedullary narrow field neuron that terminates in lobula layer 1 with a bleb-type terminal arborization and that has fine arborizations in medulla layer M2 and bleb-type arborizations in M3 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). In the medulla, it receives strong synaptic input from lamina monopolar neuron L2 (Takemura et al., 2011; Takemura et al., 2013). It outputs onto T5 neurons (Shinomiya et al., 2019). It is a cholinergic neuron (Varija Raghu et al., 2011; Shinomiya et al., 2014). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0212356
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0241236
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm1
annotated property: hasExactSynonym
annotated target: Tm1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm2
type: Class
subclass of: FBbt_00013789
subclass of: FBbt_00049541
subclass of: FBbt_00058205
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052326
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L4
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T5 neuron
IAO_0000028: Tm2
definition: Transmedullary narrow field neuron that has its main dendritic arborization in medulla layer M2 (Ting et al., 2014), where it receives input from lamina monopolar neuron L2 (Takemura et al., 2011), and additional postsynaptic terminals in M4-M5, where it receives input from lamina monopolar neuron L4 (Takemura et al., 2011). It has presynaptic terminals in layers M3, M4 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). Its axon follows the posterior edge of its cognate medulla column (Ting et al., 2014), then crosses the second optic chiasma to terminate in lobula layers 1 and 2 (Fischbach and Dittrich, 1989). In layer 1 it outputs to T5 neurons (Shinomiya et al., 2014). It is a cholinergic neuron (Varija Raghu et al., 2011; Gao et al., 2008; Takemura et al., 2011). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10144
database_cross_reference: VFB:FBbt_00003790
has exact synonym: Tm2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003790
in subset: cur
comment: The neurotransmitter has been assessed by co-labelling cells with a P{Cha-GAL4.7.4} driver (FBtp0014830) and an anti-ChAT antibody (Varija Raghu et al., 2011), by using a Cha-GAL4.DBD (FBtp002350) (Gao et al., 2008) and by neurotransmitter was assessed by single cell RT-PCR measurement of choline acetyltransferase (FBgn0000303) expression (Takemura et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014).

Axiom
annotated source: transmedullary neuron Tm2
annotated property: IAO_0000028
annotated target: Tm2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm2
annotated property: definition
annotated target: Transmedullary narrow field neuron that has its main dendritic arborization in medulla layer M2 (Ting et al., 2014), where it receives input from lamina monopolar neuron L2 (Takemura et al., 2011), and additional postsynaptic terminals in M4-M5, where it receives input from lamina monopolar neuron L4 (Takemura et al., 2011). It has presynaptic terminals in layers M3, M4 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). Its axon follows the posterior edge of its cognate medulla column (Ting et al., 2014), then crosses the second optic chiasma to terminate in lobula layers 1 and 2 (Fischbach and Dittrich, 1989). In layer 1 it outputs to T5 neurons (Shinomiya et al., 2014). It is a cholinergic neuron (Varija Raghu et al., 2011; Gao et al., 2008; Takemura et al., 2011). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0212356
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0224196
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm2
annotated property: hasExactSynonym
annotated target: Tm2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm3
type: Class
subclass of: CL_0008061
subclass of: FBbt_00013789
subclass of: FBbt_00049541
subclass of: FBbt_00058205
subclass of: FBbt_00058207
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052329
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T4 neuron
IAO_0000028: Tm3
definition: Transmedullary narrow field neuron that terminates in lobula layers 1 and 4 with bleb-like terminal arborizations. It has fine arborizations in medulla layers M1, M4, and M5, and has bleb-type arborization in medulla layers M1, M4, M9 and M10 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). Pre-synaptic terminals are present mainly in medulla layers M9-M10, but also in all other layers where neurites extend laterally (Pankova and Borst, 2017). It receives input from lamina monopolar neuron L1 and L5 and medullary intrinsic neuron Mi1 and it outputs to T4 neurons (Takemura et al., 2013). It seems to be capable of both cholinergic (Pankova & Borst, 2017) and GABAergic (Raghu et al., 2013) neurotransmission.
database_cross_reference: FlyBrain_NDB:10153
database_cross_reference: VFB:FBbt_00003791
has exact synonym: Tm3
has exact synonym: Tm3a
has exact synonym: transmedullary neuron Tm3a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003791
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. The neurotransmitter was assessed to be GABA by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA (Raghu et al., 2013). Connectivity in the medulla was assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013). Neuron was assessed to be cholinergic based on anti-HA antibody detection of HA-tagged VAChT expression (Pankova & Borst, 2017).

Axiom
annotated source: transmedullary neuron Tm3
annotated property: IAO_0000028
annotated target: Tm3
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: transmedullary neuron Tm3
annotated property: definition
annotated target: Transmedullary narrow field neuron that terminates in lobula layers 1 and 4 with bleb-like terminal arborizations. It has fine arborizations in medulla layers M1, M4, and M5, and has bleb-type arborization in medulla layers M1, M4, M9 and M10 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). Pre-synaptic terminals are present mainly in medulla layers M9-M10, but also in all other layers where neurites extend laterally (Pankova and Borst, 2017). It receives input from lamina monopolar neuron L1 and L5 and medullary intrinsic neuron Mi1 and it outputs to T4 neurons (Takemura et al., 2013). It seems to be capable of both cholinergic (Pankova & Borst, 2017) and GABAergic (Raghu et al., 2013) neurotransmission.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213020
database_cross_reference: FlyBase:FBrf0220286
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0235353

Axiom
annotated source: transmedullary neuron Tm3
annotated property: hasExactSynonym
annotated target: Tm3
database_cross_reference: FlyBase:FBrf0049410
has synonym type: VFB SYMBOL

Axiom
annotated source: transmedullary neuron Tm3
annotated property: hasExactSynonym
annotated target: Tm3a
database_cross_reference: FlyBase:FBrf0213020

Axiom
annotated source: transmedullary neuron Tm3
annotated property: hasExactSynonym
annotated target: transmedullary neuron Tm3a
database_cross_reference: FlyBase:FBrf0213020

transmedullary neuron Tm4
type: Class
subclass of: CL_0008061
subclass of: FBbt_00013789
subclass of: FBbt_00049541
subclass of: FBbt_00058205
subclass of: FBbt_00058207
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052330
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C3
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T5 neuron
IAO_0000028: Tm4
definition: Transmedullary narrow field neuron that terminates in lobula layers 1, 2 and 4 with bleb-type arborizations, and with fine arborizations in layer 3. It displays fine arborizations in medulla layers M2, M3, M4 and M9, and has bleb-type arborizations in layers M2, M4, and M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). In the medulla, receives input from lamina monopolar neuron L2 and centrifugal neuron C3 (Takemura et al., 2013). In lobula layer 1, it outputs to T5 neurons (Shinomiya et al., 2014). It seems to be capable of both cholinergic and GABAergic neurotransmission. There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10155
database_cross_reference: VFB:FBbt_00003792
has exact synonym: Tm4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003792
in subset: cur
comment: The acetylcholine neurotransmitter was assessed by co-labelling cells with a Cha-GAL4.7.4 driver (FBtp0014830) and an anti-ChAT antibody (Varija Raghu et al., 2011), and by scRNAseq detection of choline acetyltransferase (FBgn0000303) and vesicular acetylcholine transporter (FBgn0270928) expression (Davis et al., 2020). The GABA neurotransmitter was assessed by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA (Raghu et al., 2013). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM from 7 columns (Takemura et al., 2013). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014).

Axiom
annotated source: transmedullary neuron Tm4
annotated property: IAO_0000028
annotated target: Tm4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm4
annotated property: definition
annotated target: Transmedullary narrow field neuron that terminates in lobula layers 1, 2 and 4 with bleb-type arborizations, and with fine arborizations in layer 3. It displays fine arborizations in medulla layers M2, M3, M4 and M9, and has bleb-type arborizations in layers M2, M4, and M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). In the medulla, receives input from lamina monopolar neuron L2 and centrifugal neuron C3 (Takemura et al., 2013). In lobula layer 1, it outputs to T5 neurons (Shinomiya et al., 2014). It seems to be capable of both cholinergic and GABAergic neurotransmission. There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0212356
database_cross_reference: FlyBase:FBrf0220286
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm4
annotated property: hasExactSynonym
annotated target: Tm4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm5
type: Class
subclass of: transmedullary neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: FBbt_00040016
IAO_0000028: Tm5
definition: Transmedullary neuron that terminates in lobula layer 5 with bleb-type arborizations. It displays fine arborizations in medulla layers M3 and M6 and other, depending on the subtype. It has bleb-type terminals in layers M6 and M8. It has three subtypes.
database_cross_reference: FlyBrain_NDB:10157
database_cross_reference: VFB:FBbt_00003793
has exact synonym: Tm5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003793
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. In these figures, the neuron has characteristics of the three Tm5 subtypes.

Axiom
annotated source: transmedullary neuron Tm5
annotated property: IAO_0000028
annotated target: Tm5
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm5
annotated property: definition
annotated target: Transmedullary neuron that terminates in lobula layer 5 with bleb-type arborizations. It displays fine arborizations in medulla layers M3 and M6 and other, depending on the subtype. It has bleb-type terminals in layers M6 and M8. It has three subtypes.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0224070

Axiom
annotated source: transmedullary neuron Tm5
annotated property: hasExactSynonym
annotated target: Tm5
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm20
type: Class
subclass of: FBbt_00013789
subclass of: FBbt_00049541
subclass of: FBbt_00058205
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052327
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M8
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: FBbt_00040016
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R8
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: FBbt_00111516
IAO_0000028: Tm20
definition: Transmedullary neuron that has dendritic arborization in medulla layers M1-M3, as well as presynaptic sites in M8 (Fischbach and Dittrich, 1989; Gao et al., 2008). In the medulla, it spans just one column (Kind et al., 2021), and receives input from lamina monopolar neuron L3 (Takemura et al., 2013) and an R8 photoreceptor (Kind et al., 2021). Its axon follows the anterior edge of its cognate medulla column (Ting et al., 2014), then crosses the second optic chiasma and projects to lobula layer 5 (Fischbach and Dittrich, 1989; Gao et al., 2008). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It is a cholinergic neuron (Gao et al., 2008). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10145
database_cross_reference: VFB:FBbt_00003808
has exact synonym: Tm20
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003808
in subset: cur
comment: Connectivity in the medulla based on EM (Takemura et al., 2013; Kind et al., 2021). Connectivity in the lobula was assessed by GRASP and double-labeling EM (Lin et al., 2016). Neurotransmitter was assessed using a cha-GAL4DBD driver (Gao et al., 2008).

Axiom
annotated source: transmedullary neuron Tm20
annotated property: IAO_0000028
annotated target: Tm20
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm20
annotated property: definition
annotated target: Transmedullary neuron that has dendritic arborization in medulla layers M1-M3, as well as presynaptic sites in M8 (Fischbach and Dittrich, 1989; Gao et al., 2008). In the medulla, it spans just one column (Kind et al., 2021), and receives input from lamina monopolar neuron L3 (Takemura et al., 2013) and an R8 photoreceptor (Kind et al., 2021). Its axon follows the anterior edge of its cognate medulla column (Ting et al., 2014), then crosses the second optic chiasma and projects to lobula layer 5 (Fischbach and Dittrich, 1989; Gao et al., 2008). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It is a cholinergic neuron (Gao et al., 2008). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0224196
database_cross_reference: FlyBase:FBrf0230403
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm20
annotated property: hasExactSynonym
annotated target: Tm20
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

medulla tangential neuron
type: Class
subclass of: FBbt_00007579
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla
IAO_0000028: Mt
definition: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more medulla layers.
database_cross_reference: VFB:FBbt_00003836
has exact synonym: Mt
has exact synonym: medullary tangential neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003836
in subset: cur

Axiom
annotated source: medulla tangential neuron
annotated property: IAO_0000028
annotated target: Mt
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla tangential neuron
annotated property: definition
annotated target: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more medulla layers.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla tangential neuron
annotated property: hasExactSynonym
annotated target: Mt
database_cross_reference: FlyBase:FBrf0049410
has synonym type: VFB SYMBOL

lobula
type: Class
subclass of: FBbt_00025991
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045004
subclass of: Restriction
  on property: develops from
  some values from: lobula anlage
definition: Anterior domain of the adult lobula complex. It can be divided into six layers and houses many columnar neurons.
database_cross_reference: VFB:FBbt_00003852
has exact synonym: LO
has exact synonym: Lob
has OBO namespace: fly_anatomy.ontology
has related synonym: Lo
id: FBbt:00003852
in subset: BrainName
in subset: cur

Axiom
annotated source: lobula
annotated property: definition
annotated target: Anterior domain of the adult lobula complex. It can be divided into six layers and houses many columnar neurons.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0231227

Axiom
annotated source: lobula
annotated property: hasExactSynonym
annotated target: LO
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: lobula
annotated property: hasExactSynonym
annotated target: Lob
database_cross_reference: FlyBase:FBrf0212704

lobula layer 1
type: Class
subclass of: FBbt_00048344
definition: Layer of the lobula that abuts the second optic chiasm. It is defined by the bushy arborizations of the T5 neurons, and by the terminal arborizations of transmedullary neuron Tm1 and Tm9.
has alternative id: FBbt:00040012
database_cross_reference: VFB:FBbt_00003853
has exact synonym: T5 layer
has exact synonym: lobula layer Lo1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003853
in subset: cur

Axiom
annotated source: lobula layer 1
annotated property: definition
annotated target: Layer of the lobula that abuts the second optic chiasm. It is defined by the bushy arborizations of the T5 neurons, and by the terminal arborizations of transmedullary neuron Tm1 and Tm9.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula layer 1
annotated property: hasExactSynonym
annotated target: T5 layer
database_cross_reference: FlyBase:FBrf0049410

lobula layer 2
type: Class
subclass of: FBbt_00048344
definition: Layer of the lobula that is second-most from the second optic chiasm. It is defined by the arborizations of lobula tangential neuron LT5.
has alternative id: FBbt:00040013
database_cross_reference: VFB:FBbt_00003854
has exact synonym: lobula layer Lo2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003854
in subset: cur

Axiom
annotated source: lobula layer 2
annotated property: definition
annotated target: Layer of the lobula that is second-most from the second optic chiasm. It is defined by the arborizations of lobula tangential neuron LT5.
database_cross_reference: FlyBase:FBrf0049410

lobula layer 3
type: Class
subclass of: FBbt_00048344
definition: Layer of the lobula that is third-most from the second optic chiasm. It contains the arborizations of lobula tangential neuron LT6.
has alternative id: FBbt:00040014
database_cross_reference: VFB:FBbt_00003855
has exact synonym: lobula layer Lo3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003855
in subset: cur

Axiom
annotated source: lobula layer 3
annotated property: definition
annotated target: Layer of the lobula that is third-most from the second optic chiasm. It contains the arborizations of lobula tangential neuron LT6.
database_cross_reference: FlyBase:FBrf0049410

lobula layer 4
type: Class
subclass of: FBbt_00048344
definition: Layer of the lobula that is fourth-most from the second optic chiasm. It contains the terminals of the translobula plate Tlp 2, 3, 4 and 5 neurons.
has alternative id: FBbt:00040015
database_cross_reference: VFB:FBbt_00003856
has exact synonym: lobula layer Lo4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003856
in subset: cur
comment: Fischbach and Dittrich, (1989), comment that lobula layer 4 could potentially be further subdivided based on the stratified arborizations of the Tlp neurons.

Axiom
annotated source: lobula layer 4
annotated property: definition
annotated target: Layer of the lobula that is fourth-most from the second optic chiasm. It contains the terminals of the translobula plate Tlp 2, 3, 4 and 5 neurons.
database_cross_reference: FlyBase:FBrf0049410

lobula tangential neuron
type: Class
subclass of: FBbt_00007579
subclass of: FBbt_00048286
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula
IAO_0000028: LT
definition: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more layers of the lobula.
database_cross_reference: VFB:FBbt_00003859
has exact synonym: LT
has exact synonym: Lt
has exact synonym: lobular tangential neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003859
in subset: cur

Axiom
annotated source: lobula tangential neuron
annotated property: IAO_0000028
annotated target: LT
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula tangential neuron
annotated property: definition
annotated target: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more layers of the lobula.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula tangential neuron
annotated property: hasExactSynonym
annotated target: LT
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula tangential neuron
annotated property: hasExactSynonym
annotated target: Lt
database_cross_reference: FlyBase:FBrf0049410

lobula columnar neuron
type: Class
subclass of: adult optic lobe columnar neuron
subclass of: FBbt_00048286
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula
IAO_0000028: LC
definition: An extrinsic columnar neuron that innervates the lobula.
database_cross_reference: VFB:FBbt_00003870
has exact synonym: LC
has exact synonym: LCN
has exact synonym: Lcn
has exact synonym: lobular columnar neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003870
in subset: cur

Axiom
annotated source: lobula columnar neuron
annotated property: IAO_0000028
annotated target: LC
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula columnar neuron
annotated property: definition
annotated target: An extrinsic columnar neuron that innervates the lobula.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula columnar neuron
annotated property: hasExactSynonym
annotated target: LC
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula columnar neuron
annotated property: hasExactSynonym
annotated target: LCN
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula columnar neuron
annotated property: hasExactSynonym
annotated target: Lcn
database_cross_reference: FlyBase:FBrf0049410

lobula intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: lobula
subclass of: FBbt_00007577
subclass of: Restriction
  on property: synapses restricted to region
  some values from: lobula
IAO_0000028: Li
definition: Neuron that only innervates the lobula.
database_cross_reference: VFB:FBbt_00003882
has exact synonym: Li
has exact synonym: lobular intrinsic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003882
in subset: cur

Axiom
annotated source: lobula intrinsic neuron
annotated property: IAO_0000028
annotated target: Li
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula intrinsic neuron
annotated property: definition
annotated target: Neuron that only innervates the lobula.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula intrinsic neuron
annotated property: hasExactSynonym
annotated target: Li
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

lobula plate
type: Class
subclass of: FBbt_00025991
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045004
subclass of: Restriction
  on property: develops from
  some values from: lobula plate anlage
definition: Posterior domain of the adult lobula complex. It is divided into 4 layers and houses many large tangential neurons.
has alternative id: FBbt:00001947
database_cross_reference: VFB:FBbt_00003885
has exact synonym: LOP
has exact synonym: LoP
has exact synonym: lobula plate neuropil
has OBO namespace: fly_anatomy.ontology
has related synonym: Lop
id: FBbt:00003885
in subset: BrainName
in subset: cur

Axiom
annotated source: lobula plate
annotated property: definition
annotated target: Posterior domain of the adult lobula complex. It is divided into 4 layers and houses many large tangential neurons.
database_cross_reference: FlyBase:FBrf0231227
database_cross_reference: VFB_vol:00003885

Axiom
annotated source: lobula plate
annotated property: hasExactSynonym
annotated target: LOP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: lobula plate
annotated property: hasExactSynonym
annotated target: LoP
database_cross_reference: FlyBase:FBrf0212704

lobula plate intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: lobula plate
subclass of: FBbt_00007577
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0000634
subclass of: Restriction
  on property: synapses restricted to region
  some values from: lobula plate
IAO_0000028: Lpi
definition: Any interneuron that innervates only the lobula plate (Raghu and Borst, 2011).
database_cross_reference: VFB:FBbt_00003910
has exact synonym: Lpi
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003910

Axiom
annotated source: lobula plate intrinsic neuron
annotated property: IAO_0000028
annotated target: Lpi
database_cross_reference: FlyBase:FBrf0213690

Axiom
annotated source: lobula plate intrinsic neuron
annotated property: definition
annotated target: Any interneuron that innervates only the lobula plate (Raghu and Borst, 2011).
database_cross_reference: FlyBase:FBrf0213690
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: lobula plate intrinsic neuron
annotated property: hasExactSynonym
annotated target: Lpi
database_cross_reference: FlyBase:FBrf0213690
has synonym type: VFB SYMBOL

optic chiasma
type: Class
subclass of: chiasma
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
definition: The projection of axons between the lamina and medulla (first optic chiasma) or between the medulla and lobula (second optic chiasma). The linear order of axons along each horizontal row of retinotopic cartridges or columns is reversed by the chiasma.
database_cross_reference: VFB:FBbt_00003921
has exact synonym: OCH
has exact synonym: optic chiasm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003921
in subset: cur

Axiom
annotated source: optic chiasma
annotated property: definition
annotated target: The projection of axons between the lamina and medulla (first optic chiasma) or between the medulla and lobula (second optic chiasma). The linear order of axons along each horizontal row of retinotopic cartridges or columns is reversed by the chiasma.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: optic chiasma
annotated property: hasExactSynonym
annotated target: OCH
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

second optic chiasma
type: Class
subclass of: optic chiasma
subclass of: Restriction
  on property: innervates
  some values from: medulla
subclass of: Restriction
  on property: innervates
  some values from: lobula
subclass of: Restriction
  on property: innervates
  some values from: lobula plate
definition: Chiasma lying between the medulla and the lobula/lobula plate of the optic lobe (Ito et al., 2014). Between the medulla and the lobula, neuronal fibers reverse their order, inverting the anterior-posterior axis of the visual field (Ito et al., 2014; Shinomiya et al., 2019). Between the medulla and lobula plate and between the lobula and lobula plate, fibers run in parallel, conserving the axes of the visual field (Shinomiya et al., 2019). Neurons travelling between the medulla and lobula complex form around 25-30 fiber bundles of varying widths, and neurons travelling between the same two neuropil columns do not necessarily fasciculate with the same bundle (Shinomiya et al., 2019). Neurons travelling between the lobula and lobula plate form sheet-like structures, neurons from the medulla bundles also merge into these sheets (Shinomiya et al., 2019). Sheets and bundles are wrapped by glial processes (Shinomiya et al., 2019). Approximately 20,000 neurons pass through each second optic chiasma (Shinomiya et al., 2019).
database_cross_reference: VFB:FBbt_00003922
has exact synonym: OCH2
has exact synonym: inner optic chiasm
has exact synonym: second optic chiasm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003922
in subset: cur
comment: The lobula lies opposite to the lobula plate, with the columns representing the anterior visual field being furthest from the medulla. For that reason, there is no chiasms between the medulla and lobula plate (Ito et al., 2014).

Axiom
annotated source: second optic chiasma
annotated property: definition
annotated target: Chiasma lying between the medulla and the lobula/lobula plate of the optic lobe (Ito et al., 2014). Between the medulla and the lobula, neuronal fibers reverse their order, inverting the anterior-posterior axis of the visual field (Ito et al., 2014; Shinomiya et al., 2019). Between the medulla and lobula plate and between the lobula and lobula plate, fibers run in parallel, conserving the axes of the visual field (Shinomiya et al., 2019). Neurons travelling between the medulla and lobula complex form around 25-30 fiber bundles of varying widths, and neurons travelling between the same two neuropil columns do not necessarily fasciculate with the same bundle (Shinomiya et al., 2019). Neurons travelling between the lobula and lobula plate form sheet-like structures, neurons from the medulla bundles also merge into these sheets (Shinomiya et al., 2019). Sheets and bundles are wrapped by glial processes (Shinomiya et al., 2019). Approximately 20,000 neurons pass through each second optic chiasma (Shinomiya et al., 2019).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: second optic chiasma
annotated property: hasExactSynonym
annotated target: OCH2
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

deutocerebrum
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: neuromere
subclass of: Restriction
  on property: part of
  some values from: antennal segment
subclass of: Restriction
  on property: part of
  some values from: supraesophageal ganglion
definition: Neuromere of the antennal segment, located between the protocerebrum and tritocerebrum, connected to antennal nerve trunk (Urbach and Technau, 2003; Ito et al., 2014).
database_cross_reference: VFB:FBbt_00003923
has exact synonym: deuterocerebral neuromere
has exact synonym: deuterocerebrum
has exact synonym: deutocerebral neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003923
in subset: cur

Axiom
annotated source: deutocerebrum
annotated property: definition
annotated target: Neuromere of the antennal segment, located between the protocerebrum and tritocerebrum, connected to antennal nerve trunk (Urbach and Technau, 2003; Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: deutocerebrum
annotated property: hasExactSynonym
annotated target: deuterocerebral neuromere
database_cross_reference: FlyBase:FBrf0092819

antennal lobe
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: deutocerebrum
definition: Synaptic neuropil domain of the deutocerebrum that is the main target for innervation from the antennal nerve.
database_cross_reference: VFB:FBbt_00003924
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003924

Axiom
annotated source: antennal lobe
annotated property: definition
annotated target: Synaptic neuropil domain of the deutocerebrum that is the main target for innervation from the antennal nerve.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

antennal lobe glomerulus
type: Class
equivalent class: Class
  intersection of: glomerulus
  intersection of: Restriction
    on property: part of
    some values from: antennal lobe
subclass of: glomerulus
subclass of: Restriction
  on property: part of
  some values from: antennal lobe
definition: Discrete partition of the antennal lobe, defined by a specific set of sensory neurons (Bates et al., 2020). There are 51 olfactory and 7 non-olfactory (VP) glomeruli (Bates et al., 2020; Marin et al., 2020).
database_cross_reference: VFB:FBbt_00003925
has OBO namespace: fly_anatomy.ontology
has related synonym: olfactory lobe glomerulus
id: FBbt:00003925
in subset: cur

Axiom
annotated source: antennal lobe glomerulus
annotated property: definition
annotated target: Discrete partition of the antennal lobe, defined by a specific set of sensory neurons (Bates et al., 2020). There are 51 olfactory and 7 non-olfactory (VP) glomeruli (Bates et al., 2020; Marin et al., 2020).
database_cross_reference: FlyBase:FBrf0246456
database_cross_reference: FlyBase:FBrf0246460

adult antennal nerve
type: Class
subclass of: antennal nerve
subclass of: Restriction
  on property: part of
  some values from: adult head
subclass of: Restriction
  on property: part of
  some values from: adult peripheral nervous system
subclass of: Restriction
  on property: overlaps
  some values from: antenna
subclass of: Restriction
  on property: has fasciculating neuron projection
  some values from: FBbt_00007386
subclass of: Restriction
  on property: has fasciculating neuron projection
  some values from: FBbt_00100000
subclass of: Restriction
  on property: innervates
  some values from: antennal mechanosensory and motor center
subclass of: Restriction
  on property: innervates
  some values from: FBbt_00007401
definition: Nerve that carries axons associated with the antenna and upper head capsule to the brain (It et al., 2014). It enters the brain at the level of the dorsal subesophageal zone (Eichler et al., 2024). Near the brain it consists of about 1700-1800 axons (Stocker, 1979; Stocker and Gendre, 1988). Approximately 1100-1200 of these are sensory fibers from the third antennal segment, mainly axons from olfactory receptor neurons that project to the antennal lobe ventrally, at its antero-ventral corner (Stocker, 1979; Stocker and Gendre, 1988; Kamikouchi et al., 2006). The remaining 500-600 fibers stem mainly from Johnston's organ neurons and mechanosensory sensilla of the anterior head capsule, which target neuropil domains outside of the antennal lobe, including the antennal mechanosensory and motor center (Stocker, 1979; Kamikouchi et al., 2006). A few fibers from this nerve project to the gnathal ganglion and the ventrolateral protocerebrum (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00003980
has exact synonym: AN
has exact synonym: AntNv
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003980
in subset: cur
comment: Stocker and Gendre provide the antennal nerve afferent counts based on TEM micrographs (Stocker and Gendre, 1988). Gross projection patterns within the brain were elucidated by Holmes-Blest reduced silver impregnation (Stocker et al., 1990). That the antennal nerve is composed of some 1200 third antennal segments and 500-600 fibers stemming from the JON and mechanosensory sensilla is based on two lines of evidence: 24hours after amputation of the funiculus, degeneration is seen in all but 500-600 fibers entering the antennal mechanosensory and motor center (Stocker et al., 1990); and Kamikouchi et al. (2006) used enhancer trap labelling and immunolabelling of JONs to trace their projections.

Axiom
annotated source: adult antennal nerve
annotated property: definition
annotated target: Nerve that carries axons associated with the antenna and upper head capsule to the brain (It et al., 2014). It enters the brain at the level of the dorsal subesophageal zone (Eichler et al., 2024). Near the brain it consists of about 1700-1800 axons (Stocker, 1979; Stocker and Gendre, 1988). Approximately 1100-1200 of these are sensory fibers from the third antennal segment, mainly axons from olfactory receptor neurons that project to the antennal lobe ventrally, at its antero-ventral corner (Stocker, 1979; Stocker and Gendre, 1988; Kamikouchi et al., 2006). The remaining 500-600 fibers stem mainly from Johnston's organ neurons and mechanosensory sensilla of the anterior head capsule, which target neuropil domains outside of the antennal lobe, including the antennal mechanosensory and motor center (Stocker, 1979; Kamikouchi et al., 2006). A few fibers from this nerve project to the gnathal ganglion and the ventrolateral protocerebrum (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0033492
database_cross_reference: FlyBase:FBrf0047813
database_cross_reference: FlyBase:FBrf0051437
database_cross_reference: FlyBase:FBrf0194812
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0259346

Axiom
annotated source: adult antennal nerve
annotated property: hasExactSynonym
annotated target: AN
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: adult antennal nerve
annotated property: hasExactSynonym
annotated target: AntNv
database_cross_reference: FlyBase:FBrf0259346

antennal mechanosensory and motor center
type: Class
subclass of: FBbt_00051393
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045048
subclass of: Restriction
  on property: part of
  some values from: FBbt_00051418
subclass of: Restriction
  on property: innervated by
  some values from: adult antennal nerve
subclass of: Restriction
  on property: overlaps
  some values from: adult tritocerebrum
subclass of: Restriction
  on property: overlaps
  some values from: adult maxillary neuromere
subclass of: Restriction
  on property: overlaps
  some values from: adult mandibular neuromere
subclass of: Restriction
  on property: develops from part of
  some values from: FBbt_00051404
definition: Adult neuropil domain that receives the axonal projections of the Johnston organ neurons (JONs) (Ito et al., 2014). It is part of the saddle, which is found in a relatively dorsal part of the subesophageal zone (Ito et al., 2014). It develops from the anteriormost (tritocerebral) part of the larval central sensory column, which greatly increases in size as JON axons enter it via the antennal nerve during metamorphosis (Kendroud et al., 2018). Afferents of the JONs also invade the mandibular and maxillary neuromeres (Kendroud et al., 2018).
database_cross_reference: VFB:FBbt_00003982
has exact synonym: AMC
has exact synonym: AMMC
has exact synonym: antennal mechanosensory region
has exact synonym: antenno-mechanosensory center
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal lobe
id: FBbt:00003982
in subset: BrainName
in subset: cur

Axiom
annotated source: antennal mechanosensory and motor center
annotated property: definition
annotated target: Adult neuropil domain that receives the axonal projections of the Johnston organ neurons (JONs) (Ito et al., 2014). It is part of the saddle, which is found in a relatively dorsal part of the subesophageal zone (Ito et al., 2014). It develops from the anteriormost (tritocerebral) part of the larval central sensory column, which greatly increases in size as JON axons enter it via the antennal nerve during metamorphosis (Kendroud et al., 2018). Afferents of the JONs also invade the mandibular and maxillary neuromeres (Kendroud et al., 2018).
database_cross_reference: FlyBase:FBrf0194812
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0237251
database_cross_reference: VFB_vol:00003982

Axiom
annotated source: antennal mechanosensory and motor center
annotated property: hasExactSynonym
annotated target: AMC
database_cross_reference: FlyBase:FBrf0187921

Axiom
annotated source: antennal mechanosensory and motor center
annotated property: hasExactSynonym
annotated target: antenno-mechanosensory center
database_cross_reference: FlyBase:FBrf0187921

Axiom
annotated source: antennal mechanosensory and motor center
annotated property: hasRelatedSynonym
annotated target: dorsal lobe
database_cross_reference: FlyBase:FBrf0239479

broad root
type: Class
subclass of: FBbt_00007426
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: innervates
  some values from: FBbt_00007401
definition: A short axon tract containing only a few fibers which projects from the posterior of the antennal lobe, just ventral to the medial antennal lobe tract. Fibers from this tract pass into posterior brain areas, e.g. into the region of the great commissure.
database_cross_reference: VFB:FBbt_00003987
has OBO namespace: fly_anatomy.ontology
has related synonym: BR
id: FBbt:00003987
in subset: cur

Axiom
annotated source: broad root
annotated property: definition
annotated target: A short axon tract containing only a few fibers which projects from the posterior of the antennal lobe, just ventral to the medial antennal lobe tract. Fibers from this tract pass into posterior brain areas, e.g. into the region of the great commissure.
database_cross_reference: FlyBase:FBrf0006611
database_cross_reference: FlyBase:FBrf0051437

tritocerebrum
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: neuromere
subclass of: Restriction
  on property: part of
  some values from: intercalary segment
subclass of: Restriction
  on property: part of
  some values from: supraesophageal ganglion
definition: Neuromere of intercalary segment, located between the deutocerebrum and the gnathal ganglion (Urbach and Technau, 2003; Hartenstein et al., 2018).
database_cross_reference: VFB:FBbt_00003999
has exact synonym: tritocerebral neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003999
in subset: cur

Axiom
annotated source: tritocerebrum
annotated property: definition
annotated target: Neuromere of intercalary segment, located between the deutocerebrum and the gnathal ganglion (Urbach and Technau, 2003; Hartenstein et al., 2018).
database_cross_reference: FlyBase:FBrf0074226
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: tritocerebrum
annotated property: hasExactSynonym
annotated target: tritocerebral neuromere
database_cross_reference: FlyBase:FBrf0092819

gnathal ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: part of
  some values from: FBbt_00051068
definition: Region of the central nervous system consisting of the neuromeres of the three gnathal segments; mandibular, maxillary and labial (Ito et al., 2014; Hartenstein et al., 2018). It is located beneath the esophagus (Ito et al., 2014; Hartenstein et al., 2018). In the early larva, the three segmental neuromeres can be clearly identified, but they become fused during development and their segmental organization is obscured in the adult (Hartenstein et al., 2018).
database_cross_reference: VFB:FBbt_00004013
has exact synonym: GNG
has exact synonym: SEG
has exact synonym: SOG
has exact synonym: subesophageal ganglion
has exact synonym: suboesophageal ganglion
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004013
in subset: cur

Axiom
annotated source: gnathal ganglion
annotated property: definition
annotated target: Region of the central nervous system consisting of the neuromeres of the three gnathal segments; mandibular, maxillary and labial (Ito et al., 2014; Hartenstein et al., 2018). It is located beneath the esophagus (Ito et al., 2014; Hartenstein et al., 2018). In the early larva, the three segmental neuromeres can be clearly identified, but they become fused during development and their segmental organization is obscured in the adult (Hartenstein et al., 2018).
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: gnathal ganglion
annotated property: hasExactSynonym
annotated target: GNG
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: gnathal ganglion
annotated property: hasExactSynonym
annotated target: SEG
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: gnathal ganglion
annotated property: hasExactSynonym
annotated target: subesophageal ganglion
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: gnathal ganglion
annotated property: hasExactSynonym
annotated target: suboesophageal ganglion
database_cross_reference: FlyBase:FBrf0080339

adult cervical connective
type: Class
subclass of: tract
subclass of: Restriction
  on property: part of
  some values from: adult central nervous system
subclass of: Restriction
  on property: overlaps
  some values from: neck
subclass of: Restriction
  on property: innervates
  some values from: adult ventral nerve cord
subclass of: Restriction
  on property: innervates
  some values from: FBbt_00014013
definition: Adult tract connecting the brain to the ventral nerve cord (Ito et al., 2014; Court et al., 2020). It emerges from the posterior gnathal ganglion (Ito et al., 2014; Court et al., 2020) and consists of 4 bundles of neurites in two bilateral pairs (one dorsal pair, one ventral pair) (Power, 1948). It contains around 3700 axons (Phelps et al., 2021).
database_cross_reference: VFB:FBbt_00004019
has exact synonym: CC
has exact synonym: CCT
has exact synonym: CV
has exact synonym: CvC
has exact synonym: CvCon
has exact synonym: cephalo-thoracic cord
has exact synonym: cephalo-thoracic nerve strand
has exact synonym: neck connective
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004019
in subset: cur

Axiom
annotated source: adult cervical connective
annotated property: definition
annotated target: Adult tract connecting the brain to the ventral nerve cord (Ito et al., 2014; Court et al., 2020). It emerges from the posterior gnathal ganglion (Ito et al., 2014; Court et al., 2020) and consists of 4 bundles of neurites in two bilateral pairs (one dorsal pair, one ventral pair) (Power, 1948). It contains around 3700 axons (Phelps et al., 2021).
database_cross_reference: FlyBase:FBrf0007196
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0246815
database_cross_reference: FlyBase:FBrf0247998

Axiom
annotated source: adult cervical connective
annotated property: hasExactSynonym
annotated target: CC
database_cross_reference: FlyBase:FBrf0219809

Axiom
annotated source: adult cervical connective
annotated property: hasExactSynonym
annotated target: CCT
database_cross_reference: FlyBase:FBrf0223329

Axiom
annotated source: adult cervical connective
annotated property: hasExactSynonym
annotated target: CV
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: adult cervical connective
annotated property: hasExactSynonym
annotated target: CvC
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult cervical connective
annotated property: hasExactSynonym
annotated target: CvCon
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult cervical connective
annotated property: hasExactSynonym
annotated target: cephalo-thoracic cord
database_cross_reference: FlyBase:FBrf0007733

Axiom
annotated source: adult cervical connective
annotated property: hasExactSynonym
annotated target: cephalo-thoracic nerve strand
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult cervical connective
annotated property: hasExactSynonym
annotated target: neck connective
database_cross_reference: FlyBase:FBrf0239335

adult subesophageal sensory interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: FBbt_00051393
subclass of: FBbt_00052046
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: FBbt_00051393
definition: Neuron of the adult central nervous system that has arborization in the sensory neuropil of the subesophageal zone.
database_cross_reference: VFB:FBbt_00004037
has narrow synonym: adult labial interneuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004037
in subset: cur

Axiom
annotated source: adult subesophageal sensory interneuron
annotated property: definition
annotated target: Neuron of the adult central nervous system that has arborization in the sensory neuropil of the subesophageal zone.
database_cross_reference: FlyBase:FBrf0042883

Axiom
annotated source: adult subesophageal sensory interneuron
annotated property: hasNarrowSynonym
annotated target: adult labial interneuron
database_cross_reference: FlyBase:FBrf0042883

adult ventral nerve cord
type: Class
subclass of: ventral nerve cord
subclass of: ganglion
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult central nervous system
subclass of: Restriction
  on property: develops from
  some values from: larval ventral nerve cord
definition: The region of the adult central nervous system posterior to the brain, containing all of the thoracic and abdominal neuromeres (Court et al., 2020). It exists as a single consolidated ganglion located in the ventral part of the thorax (Court et al., 2020). It is connected to the brain by descending and ascending neurons that pass through the neck connective (Court et al., 2020).
database_cross_reference: VFB:FBbt_00004052
has exact synonym: TAC
has exact synonym: TAG
has exact synonym: adult ThGng
has exact synonym: adult VNC
has exact synonym: adult VNS
has exact synonym: adult ventral nervous system
has exact synonym: thoracico-abdominal center
has exact synonym: thoracico-abdominal ganglia
has exact synonym: thoracico-abdominal ganglion
has exact synonym: thoracico-abdominal nervous system
has exact synonym: thoracicoabdominal ganglion
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004052
in subset: cur

Axiom
annotated source: adult ventral nerve cord
annotated property: definition
annotated target: The region of the adult central nervous system posterior to the brain, containing all of the thoracic and abdominal neuromeres (Court et al., 2020). It exists as a single consolidated ganglion located in the ventral part of the thorax (Court et al., 2020). It is connected to the brain by descending and ascending neurons that pass through the neck connective (Court et al., 2020).
database_cross_reference: FlyBase:FBrf0007196
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: TAC
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: TAG
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: adult ThGng
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: adult VNC
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: adult VNS
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: adult ventral nervous system
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: thoracico-abdominal center
database_cross_reference: FlyBase:FBrf0007196

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: thoracico-abdominal ganglia
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: thoracico-abdominal ganglion
database_cross_reference: FlyBase:FBrf0246815

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: thoracico-abdominal nervous system
database_cross_reference: FlyBase:FBrf0007196

Axiom
annotated source: adult ventral nerve cord
annotated property: hasExactSynonym
annotated target: thoracicoabdominal ganglion
database_cross_reference: FlyBase:FBrf0246815

prothoracic neuromere
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: FBbt_00111026
subclass of: Restriction
  on property: part of
  some values from: prothoracic segment
definition: Any neuromere (FBbt:00005140) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: VFB:FBbt_00004054
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004054
in subset: cur

Axiom
annotated source: prothoracic neuromere
annotated property: definition
annotated target: Any neuromere (FBbt:00005140) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

mesothoracic neuromere
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: FBbt_00111026
subclass of: Restriction
  on property: part of
  some values from: mesothoracic segment
definition: Any neuromere (FBbt:00005140) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: VFB:FBbt_00004059
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004059
in subset: cur

Axiom
annotated source: mesothoracic neuromere
annotated property: definition
annotated target: Any neuromere (FBbt:00005140) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: FBC:Autogenerated

indirect flight muscle motor neuron
type: Class
equivalent class: Class
  intersection of: motor neuron
  intersection of: Restriction
    on property: sends synaptic output to cell
    some values from: indirect flight muscle cell
subclass of: FBbt_00047247
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: indirect flight muscle cell
definition: Motor neuron that innervates the indirect flight muscles.
database_cross_reference: VFB:FBbt_00004074
has exact synonym: wing control muscle motoneuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004074
in subset: cur

Axiom
annotated source: indirect flight muscle motor neuron
annotated property: definition
annotated target: Motor neuron that innervates the indirect flight muscles.
database_cross_reference: FlyBase:FBrf0048552
database_cross_reference: doi:10.1101/2023.05.31.542897

Axiom
annotated source: indirect flight muscle motor neuron
annotated property: hasExactSynonym
annotated target: wing control muscle motoneuron
database_cross_reference: doi:10.1101/2023.05.31.542897

metathoracic neuromere
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: FBbt_00111026
subclass of: Restriction
  on property: part of
  some values from: metathoracic segment
definition: Any neuromere (FBbt:00005140) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: VFB:FBbt_00004092
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004092
in subset: cur

Axiom
annotated source: metathoracic neuromere
annotated property: definition
annotated target: Any neuromere (FBbt:00005140) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: FBC:Autogenerated

abdominal neuromere
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment
subclass of: neuromere
subclass of: Restriction
  on property: part of
  some values from: abdominal segment
subclass of: Restriction
  on property: part of
  some values from: ventral nerve cord
definition: Any neuromere (FBbt:00005140) that is part of some abdominal segment (FBbt:00000021).
database_cross_reference: VFB:FBbt_00004097
has OBO namespace: fly_anatomy.ontology
has related synonym: abdominal ganglion
id: FBbt:00004097
in subset: cur

Axiom
annotated source: abdominal neuromere
annotated property: definition
annotated target: Any neuromere (FBbt:00005140) that is part of some abdominal segment (FBbt:00000021).
database_cross_reference: FBC:Autogenerated

peptidergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0002790
subclass of: neuron
subclass of: Restriction
  on property: capable of
  some values from: GO_0002790
definition: Any neuron (FBbt:00005106) that is capable of some peptide secretion (GO:0002790).
database_cross_reference: CL:0000110
database_cross_reference: VFB:FBbt_00004101
has OBO namespace: fly_anatomy.ontology
has related synonym: peptinergic neuron
id: FBbt:00004101
in subset: cur

Axiom
annotated source: peptidergic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some peptide secretion (GO:0002790).
database_cross_reference: FlyBase:FBrf0052426

adult sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Any sense organ of the adult.
database_cross_reference: VFB:FBbt_00004113
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004113
in subset: cur

Axiom
annotated source: adult sense organ
annotated property: definition
annotated target: Any sense organ of the adult.
database_cross_reference: FlyBase:FBrf0007734
database_cross_reference: FlyBase:FBrf0031004

head sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: head
subclass of: sensillum
subclass of: Restriction
  on property: part of
  some values from: head
definition: Any sensillum (FBbt:00007152) that is part of some head (FBbt:00000004).
database_cross_reference: UBERON:0000963
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004114
in subset: cur

Axiom
annotated source: head sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some head (FBbt:00000004).
database_cross_reference: FBC:Autogenerated

adult head bristle
type: Class
equivalent class: Class
  intersection of: chaeta
  intersection of: Restriction
    on property: part of
    some values from: adult head
subclass of: chaeta
subclass of: FBbt_00007241
definition: Any chaeta (FBbt:00005177) that is part of some adult head (FBbt:00003007).
database_cross_reference: VFB:FBbt_00004115
has exact synonym: adult head chaeta
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004115
in subset: cur

Axiom
annotated source: adult head bristle
annotated property: definition
annotated target: Any chaeta (FBbt:00005177) that is part of some adult head (FBbt:00003007).
database_cross_reference: FBC:Autogenerated

pharyngeal sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: part of
    some values from: pharynx
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: pharynx
definition: Any sense organ (FBbt:00005155) that is part of some pharynx (FBbt:00005380).
database_cross_reference: VFB:FBbt_00004135
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004135
in subset: cur

Axiom
annotated source: pharyngeal sense organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is part of some pharynx (FBbt:00005380).
database_cross_reference: FlyBase:FBrf0068700

Johnston organ
type: Class
subclass of: antennal segment 2 sense organ
subclass of: FBbt_00007236
subclass of: FBbt_00007686
subclass of: FBbt_00052719
subclass of: Restriction
  on property: continuous with
  some values from: FBbt_00100001
subclass of: Restriction
  on property: capable of
  some values from: GO_0050973
subclass of: Restriction
  on property: capable of
  some values from: GO_0071066
definition: Compound chordotonal organ of antennal segment 2 involved in hearing (Gopfert and Robert, 2002), direction-sensitive wind detection (Yorozu et al., 2009) and gravitaxis (Kamikouchi et al., 2009). The actin-filament rich basal tips of the Johnston's organ scolopidia connect to the inner surface of antennal segment 2, and the apical tips connect to the hook of antennal segment 3 (Gopfert and Robert, 2002). Its sensory neurons (Johnston's organ neurons or JONs) are connected to the Johnston's organ nerve (Kamikouchi et al., 2006), and predominantly innervate the antennal mechanosensory and motor center (AMMC). There are 477 +/- 24 cell bodies, arranged in a bowl shape lying vertically with the 'top' facing the lateral side, and forming a ring around the antennal nerve (Kamikouchi et al., 2006). JONs connecting to opposing sides of the hook are alternatively stimulated by stretching or compression according to the hook's oscillatory movement (Gopfert and Robert, 2002).
database_cross_reference: VFB:FBbt_00004178
has exact synonym: JO
has exact synonym: Johnston's organ
has OBO namespace: fly_anatomy.ontology
has related synonym: chordotonal organ of antennal segment 2
id: FBbt:00004178
in subset: FB gloss
in subset: cur
comment: Yorozu et al., 2009, identify tonically activated Johnston's organ neurons that respond to forward or reverse deflection of the antenna. Genetic ablation of these neurons inhibits wind-induced behavioral responses without impairing hearing. Further, by expression of tetanus toxin, Kamikouchi et al., 2009, identify the same neuronal population as essential for gravitaxis behavior.

Axiom
annotated source: Johnston organ
annotated property: definition
annotated target: Compound chordotonal organ of antennal segment 2 involved in hearing (Gopfert and Robert, 2002), direction-sensitive wind detection (Yorozu et al., 2009) and gravitaxis (Kamikouchi et al., 2009). The actin-filament rich basal tips of the Johnston's organ scolopidia connect to the inner surface of antennal segment 2, and the apical tips connect to the hook of antennal segment 3 (Gopfert and Robert, 2002). Its sensory neurons (Johnston's organ neurons or JONs) are connected to the Johnston's organ nerve (Kamikouchi et al., 2006), and predominantly innervate the antennal mechanosensory and motor center (AMMC). There are 477 +/- 24 cell bodies, arranged in a bowl shape lying vertically with the 'top' facing the lateral side, and forming a ring around the antennal nerve (Kamikouchi et al., 2006). JONs connecting to opposing sides of the hook are alternatively stimulated by stretching or compression according to the hook's oscillatory movement (Gopfert and Robert, 2002).
database_cross_reference: FlyBase:FBrf0147122
database_cross_reference: FlyBase:FBrf0166419
database_cross_reference: FlyBase:FBrf0179481
database_cross_reference: FlyBase:FBrf0187921
database_cross_reference: FlyBase:FBrf0194812
database_cross_reference: FlyBase:FBrf0207559

Axiom
annotated source: Johnston organ
annotated property: hasExactSynonym
annotated target: JO
database_cross_reference: FlyBase:FBrf0210248

cone cell
type: Class
subclass of: sensory organ cell
subclass of: Restriction
  on property: part of
  some values from: ommatidium
definition: A cell type of the ommatidium. Each ommatidium contains four cone cells. The four cell bodies form a plate that is the floor of the pseudocone and the roof of the rhabdomere chamber. The surface facing the pseudocone is covered with small papillae that secrete lens materials. The lower surface, facing the photoreceptors, makes numerous hemi-desmosomes with the extracellular cap above the rhabdomeres. Each cone cell extends a thin process, the inter-retinular fiber, between the photoreceptors to the base of the ommatidium where it makes a foot. The four cone cell feet make a plug at the base of the rhabdomere chamber. Cone cells contain coarse ommochrome pigment granules.
database_cross_reference: CL:0000718
database_cross_reference: VFB:FBbt_00004193
has exact synonym: Semper's cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004193
in subset: cur

Axiom
annotated source: cone cell
annotated property: definition
annotated target: A cell type of the ommatidium. Each ommatidium contains four cone cells. The four cell bodies form a plate that is the floor of the pseudocone and the roof of the rhabdomere chamber. The surface facing the pseudocone is covered with small papillae that secrete lens materials. The lower surface, facing the photoreceptors, makes numerous hemi-desmosomes with the extracellular cap above the rhabdomeres. Each cone cell extends a thin process, the inter-retinular fiber, between the photoreceptors to the base of the ommatidium where it makes a foot. The four cone cell feet make a plug at the base of the rhabdomere chamber. Cone cells contain coarse ommochrome pigment granules.
database_cross_reference: FlyBase:FBrf0064798

Axiom
annotated source: cone cell
annotated property: hasExactSynonym
annotated target: Semper's cell
database_cross_reference: FlyBase:FBrf0064798

retina
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: part of
  some values from: adult peripheral nervous system
definition: The array of photoreceptors and the cells that support them in a compound eye.
database_cross_reference: UBERON:0005388
database_cross_reference: VFB:FBbt_00004200
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004200
in subset: FB gloss
in subset: cur
comment: This is a very loosely used term. Definition based on consensus usage in literature.

Axiom
annotated source: retina
annotated property: definition
annotated target: The array of photoreceptors and the cells that support them in a compound eye.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

hindgut anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: posterior endoderm anlage
subclass of: Restriction
  on property: develops from
  some values from: hindgut anlage in statu nascendi
subclass of: Restriction
  on property: develops into
  some values from: inclusive hindgut primordium
definition: A(n) anlage that develops into some inclusive hindgut primordium. It develops from some hindgut anlage in statu nascendi.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004202
in subset: cur

Axiom
annotated source: hindgut anlage
annotated property: definition
annotated target: A(n) anlage that develops into some inclusive hindgut primordium. It develops from some hindgut anlage in statu nascendi.
database_cross_reference: FBC:Autogenerated

ventral ectoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: ectoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: ventral ectoderm
definition: Anlage that develops into the ventral ectoderm. It is found in the lateroventral trunk region of the embryo at the cellular blastoderm stage, prior to gastrulation (Stathopoulos and Newcomb, 2020).
has exact synonym: presumptive neuroectoderm
has exact synonym: ventral/neuroectoderm anlage
has OBO namespace: fly_anatomy.ontology
has related synonym: Asn/A VenEc
id: FBbt:00004204
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral ectoderm anlage
annotated property: definition
annotated target: Anlage that develops into the ventral ectoderm. It is found in the lateroventral trunk region of the embryo at the cellular blastoderm stage, prior to gastrulation (Stathopoulos and Newcomb, 2020).
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: ventral ectoderm anlage
annotated property: hasExactSynonym
annotated target: presumptive neuroectoderm
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: ventral ectoderm anlage
annotated property: hasExactSynonym
annotated target: ventral/neuroectoderm anlage
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: ventral ectoderm anlage
annotated property: hasRelatedSynonym
annotated target: Asn/A VenEc
database_cross_reference: https://orcid.org/0000-0002-7073-9172

developing embryonic structure
type: Class
equivalent class: Class
  intersection of: developing material anatomical entity
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: developing material anatomical entity
subclass of: Restriction
  on property: part of
  some values from: embryo
definition: Any developing material anatomical entity of the embryo.
database_cross_reference: UBERON:0002050
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004208
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: developing embryonic structure
annotated property: definition
annotated target: Any developing material anatomical entity of the embryo.
database_cross_reference: FBC:Autogenerated

photoreceptor neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0016056
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050962
subclass of: sensory neuron
subclass of: FBbt_00047736
subclass of: Restriction
  on property: capable of
  some values from: GO_0016056
subclass of: Restriction
  on property: capable of
  some values from: GO_0050962
definition: Sensory neuron that reacts to the presence of light, due to the presence of rhodopsin.
database_cross_reference: CL:0000210
database_cross_reference: VFB:FBbt_00004211
has exact synonym: photoreceptor cell
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell
id: FBbt:00004211
in subset: cur

Axiom
annotated source: photoreceptor neuron
annotated property: definition
annotated target: Sensory neuron that reacts to the presence of light, due to the presence of rhodopsin.
database_cross_reference: FlyBase:FBrf0239342

photoreceptor cell R1
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048003
IAO_0000028: R1
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the right angle vertex of the longer of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003710
database_cross_reference: CL:0000687
database_cross_reference: VFB:FBbt_00004213
has exact synonym: R1
has exact synonym: lamina receptor cell R1
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R1
id: FBbt:00004213
in subset: cur
comment: The name photoreceptor cell R1 is occasionally, mistakenly assumed to refer to any Rh1 (ninaE) expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R1 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (40/-), L2 (46/1), L3 (11/-), L4 (-/2), Lai (36/-), Lawf (1/1), epithelial glia (15/-), surface glia (1/-) and marginal glia (1/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R1
annotated property: IAO_0000028
annotated target: R1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R1
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the right angle vertex of the longer of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R1
annotated property: hasExactSynonym
annotated target: R1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R2
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048004
IAO_0000028: R2
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located in the middle of the longer of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003711
database_cross_reference: CL:0000690
database_cross_reference: VFB:FBbt_00004215
has exact synonym: R2
has exact synonym: lamina receptor cell R2
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R2
id: FBbt:00004215
in subset: cur
comment: The name photoreceptor cell R2 is occasionally, mistakenly assumed to refer to any Rh2 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R2 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (43/-), L2 (45/1), L3 (10/-), L4 (-/1), Lai (39/-), T1 (2/-), Lawf (-/3), epithelial glia (13/-) and surface glia (1/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R2
annotated property: IAO_0000028
annotated target: R2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R2
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located in the middle of the longer of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R2
annotated property: hasExactSynonym
annotated target: R2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R3
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048005
IAO_0000028: R3
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the non-right angled vertex of the longer of two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003712
database_cross_reference: CL:0000694
database_cross_reference: VFB:FBbt_00004217
has exact synonym: R3
has exact synonym: lamina receptor cell R3
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R3
id: FBbt:00004217
in subset: cur
comment: The name photoreceptor cell R3 is occasionally, mistakenly assumed to refer to any Rh3 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R3 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (37/-), L2 (39/-), L3 (4/-), L4 (-/3), Lai (39/-), T1 (2/-), C3 (2/1), Lawf (-/1) and epithelial glia (7/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R3
annotated property: IAO_0000028
annotated target: R3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R3
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the non-right angled vertex of the longer of two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R3
annotated property: hasExactSynonym
annotated target: R3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R4
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048006
IAO_0000028: R4
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located in the middle of the longer of the two non-parallel sides of trapezoid of rhabdomeres in each ommatidium, in between the rhabdomeres of R3 and R5. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003713
database_cross_reference: CL:0000697
database_cross_reference: VFB:FBbt_00004219
has exact synonym: R4
has exact synonym: lamina receptor cell R4
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R4
id: FBbt:00004219
in subset: cur
comment: The name photoreceptor cell R4 is occasionally, mistakenly assumed to refer to any Rh4 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R4 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (38/-), L2 (41/-), L3 (8/-), L4 (-/1), Lai (37/2), T1 (2/-) and epithelial glia (9/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R4
annotated property: IAO_0000028
annotated target: R4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R4
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located in the middle of the longer of the two non-parallel sides of trapezoid of rhabdomeres in each ommatidium, in between the rhabdomeres of R3 and R5. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R4
annotated property: hasExactSynonym
annotated target: R4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R5
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048007
IAO_0000028: R5
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located at a non-right angle vertex of the shorter of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003714
database_cross_reference: CL:0000702
database_cross_reference: VFB:FBbt_00004221
has exact synonym: R5
has exact synonym: lamina receptor cell R5
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R5
id: FBbt:00004221
in subset: cur
comment: The name photoreceptor cell R5 is occasionally, mistakenly assumed to refer to any Rh5 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R5 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (38/-), L2 (39/-), L3 (6/-), L4 (-/3), Lai (35/2), C2 (1/-), epithelial glia (10/-) and marginal glia (1/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R5
annotated property: IAO_0000028
annotated target: R5
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R5
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located at a non-right angle vertex of the shorter of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R5
annotated property: hasExactSynonym
annotated target: R5
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R6
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048008
IAO_0000028: R6
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the right angle vertex of the shorter of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003715
database_cross_reference: CL:0000705
database_cross_reference: VFB:FBbt_00004223
has exact synonym: R6
has exact synonym: lamina receptor cell R6
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R6
id: FBbt:00004223
in subset: cur
comment: The name photoreceptor cell R6 is occasionally, mistakenly assumed to refer to any Rh6 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R6 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (45/-), L2 (47/-), L3 (12/-), L4 (-/3), Lai (40/-), Lawf (-/1), epithelial glia (11/-) and marginal glia (2/-)(Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R6
annotated property: IAO_0000028
annotated target: R6
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R6
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the right angle vertex of the shorter of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R6
annotated property: hasExactSynonym
annotated target: R6
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R7
type: Class
subclass of: inner photoreceptor cell
subclass of: Restriction
  on property: overlaps
  some values from: optic cartridge
subclass of: Restriction
  on property: overlaps
  some values from: first optic chiasma
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048009
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M6
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R8
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: photoreceptor cell R8
IAO_0000028: R7
definition: Inner photoreceptor cell of the ommatidium whose rhabdomere is located distally, directly above that of R8 (Wernet and Desplan, 2004). It has a single axon that extends through a single column of the lamina without making synapses (Fischbach and Dittrich, 1989). This axon crosses the first optic chiasm and extends through a single column of the medulla where it makes pre-synaptic contacts, mainly in medulla layers M1 and M5 (Takemura et al., 2008), before terminating in M6 (Gao et al., 2008; Sancer et al., 2019). It forms reciprocal inhibitory histaminergic synapses with the R8 photoreceptor of the same optic column (Schnaitmann et al., 2018), with a large proportion in the first optic chiasm (Kind et al., 2021).
has alternative id: FBbt:00003716
database_cross_reference: CL:0000707
database_cross_reference: FlyBrain_NDB:10112
database_cross_reference: VFB:FBbt_00004225
has exact synonym: R7
has exact synonym: lamina receptor cell R7
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R7
id: FBbt:00004225
in subset: cur
comment: This term refers to a type of adult eye photoreceptor cell, defined based on the position of its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready (1993). It does not refer to Rh7-expressing photoreceptors.

Axiom
annotated source: photoreceptor cell R7
annotated property: IAO_0000028
annotated target: R7
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R7
annotated property: definition
annotated target: Inner photoreceptor cell of the ommatidium whose rhabdomere is located distally, directly above that of R8 (Wernet and Desplan, 2004). It has a single axon that extends through a single column of the lamina without making synapses (Fischbach and Dittrich, 1989). This axon crosses the first optic chiasm and extends through a single column of the medulla where it makes pre-synaptic contacts, mainly in medulla layers M1 and M5 (Takemura et al., 2008), before terminating in M6 (Gao et al., 2008; Sancer et al., 2019). It forms reciprocal inhibitory histaminergic synapses with the R8 photoreceptor of the same optic column (Schnaitmann et al., 2018), with a large proportion in the first optic chiasm (Kind et al., 2021).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0237706
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: photoreceptor cell R7
annotated property: hasExactSynonym
annotated target: R7
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R8
type: Class
subclass of: inner photoreceptor cell
subclass of: FBbt_00058205
subclass of: Restriction
  on property: overlaps
  some values from: optic cartridge
subclass of: Restriction
  on property: overlaps
  some values from: first optic chiasma
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048010
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R7
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: photoreceptor cell R7
IAO_0000028: R8
definition: Inner photoreceptor cell of the ommatidium whose rhabdomere is located proximally, directly below that of R7 (Wernet and Desplan, 2004). It has a single axon that extends through a single column of the lamina without making synapses and crosses the first optic chiasm to reach the medulla (Fischbach and Dittrich, 1989). It forms reciprocal inhibitory histaminergic synapses with the R8 photoreceptor of the same optic column (Schnaitmann et al., 2018), with a large proportion in the first optic chiasm (Kind et al., 2021). It is also cholinergic (Davis et al., 2020).
has alternative id: FBbt:00003717
database_cross_reference: CL:0000709
database_cross_reference: FlyBrain_NDB:10113
database_cross_reference: FlyBrain_NDB:10114
database_cross_reference: VFB:FBbt_00004227
has exact synonym: R8
has exact synonym: lamina receptor cell R8
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R8
id: FBbt:00004227
in subset: cur
comment: Fischbach and Dittrich (1989) suggest there may be two (non-DRA) variants of R8, one terminating in each of M3 and M4; this has not been substantiated in subsequent papers.

Axiom
annotated source: photoreceptor cell R8
annotated property: IAO_0000028
annotated target: R8
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R8
annotated property: definition
annotated target: Inner photoreceptor cell of the ommatidium whose rhabdomere is located proximally, directly below that of R7 (Wernet and Desplan, 2004). It has a single axon that extends through a single column of the lamina without making synapses and crosses the first optic chiasm to reach the medulla (Fischbach and Dittrich, 1989). It forms reciprocal inhibitory histaminergic synapses with the R8 photoreceptor of the same optic column (Schnaitmann et al., 2018), with a large proportion in the first optic chiasm (Kind et al., 2021). It is also cholinergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0237706
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: photoreceptor cell R8
annotated property: hasExactSynonym
annotated target: R8
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

pigment cell
type: Class
subclass of: sensory organ cell
subclass of: FBbt_00058258
subclass of: Restriction
  on property: part of
  some values from: retina
definition: Glial cell of the retina (Edwards and Meinertzhagen, 2010; Liu et al., 2015) that produces screening pigments (Tomlinson, 2012). These pigments form layers around the retina and each ommatidium to prevent lateral transfer of light, ensuring photoreceptors of one ommatidium are activated only by light entering through one lens (Tomlinson, 2012). These cells also have metabolic interactions with photoreceptor neurons, providing alanine (Edwards and Meinertzhagen, 2010) and removing lipids (Liu et al., 2015).
database_cross_reference: CL:0001658
database_cross_reference: VFB:FBbt_00004230
has exact synonym: pigment glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004230
in subset: cur

Axiom
annotated source: pigment cell
annotated property: definition
annotated target: Glial cell of the retina (Edwards and Meinertzhagen, 2010; Liu et al., 2015) that produces screening pigments (Tomlinson, 2012). These pigments form layers around the retina and each ommatidium to prevent lateral transfer of light, ensuring photoreceptors of one ommatidium are activated only by light entering through one lens (Tomlinson, 2012). These cells also have metabolic interactions with photoreceptor neurons, providing alanine (Edwards and Meinertzhagen, 2010) and removing lipids (Liu et al., 2015).
database_cross_reference: FlyBase:FBrf0210316
database_cross_reference: FlyBase:FBrf0218541
database_cross_reference: FlyBase:FBrf0227305

Axiom
annotated source: pigment cell
annotated property: hasExactSynonym
annotated target: pigment glial cell
database_cross_reference: FlyBase:FBrf0227305

ocellar retinula cell
type: Class
subclass of: sensory organ cell
subclass of: FBbt_00007251
subclass of: FBbt_00058244
subclass of: Restriction
  on property: overlaps
  some values from: ocellus
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0042331
subclass of: Restriction
  on property: expresses
  some values from: FBgn0003248
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: FBbt_00049817
definition: Photoreceptor cell of an adult ocellus. It expresses the violet-sensitive Rh2 (Jean-Guillaume and Kumar, 2022). Its axons are found proximal to its nucleus, and they target their corresponding ocellar ganglion (Caldwell et al., 2007). The lateral ocelli each have around 100 photoreceptor cells, whereas the medial one has around 75 (Dorkenwald et al., 2024). Some of these cells directly target the lobula or lobula plate (Jean-Guillaume and Kumar, 2022). These cells aid flight stabilization and augment the phototactic response (Jean-Guillaume and Kumar, 2022). They form simpler circuits with fewer connections before reaching the central brain, resulting in faster transmission of information (Jean-Guillaume and Kumar, 2022).
database_cross_reference: VFB:FBbt_00004242
has exact synonym: ocellar photoreceptor cell
has exact synonym: ocellus photoreceptor
has exact synonym: ocellus retinula cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004242
in subset: cur

Axiom
annotated source: ocellar retinula cell
annotated property: definition
annotated target: Photoreceptor cell of an adult ocellus. It expresses the violet-sensitive Rh2 (Jean-Guillaume and Kumar, 2022). Its axons are found proximal to its nucleus, and they target their corresponding ocellar ganglion (Caldwell et al., 2007). The lateral ocelli each have around 100 photoreceptor cells, whereas the medial one has around 75 (Dorkenwald et al., 2024). Some of these cells directly target the lobula or lobula plate (Jean-Guillaume and Kumar, 2022). These cells aid flight stabilization and augment the phototactic response (Jean-Guillaume and Kumar, 2022). They form simpler circuits with fewer connections before reaching the central brain, resulting in faster transmission of information (Jean-Guillaume and Kumar, 2022).
database_cross_reference: FlyBase:FBrf0050358
database_cross_reference: FlyBase:FBrf0200339
database_cross_reference: FlyBase:FBrf0255165
database_cross_reference: FlyBase:FBrf0260546

Axiom
annotated source: ocellar retinula cell
annotated property: hasExactSynonym
annotated target: ocellar photoreceptor cell
database_cross_reference: FlyBase:FBrf0255165

adult thoracic sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: adult thorax
subclass of: FBbt_00007239
subclass of: Restriction
  on property: part of
  some values from: adult thorax
definition: Any sensillum (FBbt:00007152) that is part of some adult thorax (FBbt:00003018).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004245
in subset: cur

Axiom
annotated source: adult thoracic sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some adult thorax (FBbt:00003018).
database_cross_reference: FBC:Autogenerated

leg sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: leg
subclass of: adult thoracic sensillum
subclass of: Restriction
  on property: part of
  some values from: leg
definition: Any sensillum (FBbt:00007152) that is part of some leg (FBbt:00004640).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004246
in subset: cur

Axiom
annotated source: leg sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some leg (FBbt:00004640).
database_cross_reference: FBC:Autogenerated

adult prothoracic sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007239
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: adult thoracic sensillum
subclass of: Restriction
  on property: part of
  some values from: adult prothoracic segment
definition: Any adult sensillum (FBbt:00007239) that is part of some prothoracic segment (FBbt:00000017).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004247
in subset: cur

Axiom
annotated source: adult prothoracic sensillum
annotated property: definition
annotated target: Any adult sensillum (FBbt:00007239) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

chordotonal organ of prothoracic segment
type: Class
equivalent class: Class
  intersection of: chordotonal organ
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: chordotonal organ
subclass of: Restriction
  on property: part of
  some values from: prothoracic segment
definition: Any chordotonal organ (FBbt:00005215) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: VFB:FBbt_00004248
has exact synonym: prothoracic chordotonal organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004248
in subset: cur

Axiom
annotated source: chordotonal organ of prothoracic segment
annotated property: definition
annotated target: Any chordotonal organ (FBbt:00005215) that is part of some prothoracic segment (FBbt:00000017).
database_cross_reference: FBC:Autogenerated

prothoracic leg sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: prothoracic leg
subclass of: leg sensillum
subclass of: adult prothoracic sensillum
subclass of: Restriction
  on property: part of
  some values from: prothoracic leg
definition: Any sensillum (FBbt:00007152) that is part of some prothoracic leg (FBbt:00004663).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004252
in subset: cur

Axiom
annotated source: prothoracic leg sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some prothoracic leg (FBbt:00004663).
database_cross_reference: FBC:Autogenerated

prothoracic leg taste bristle
type: Class
equivalent class: Class
  intersection of: chaeta
  intersection of: Restriction
    on property: part of
    some values from: prothoracic leg
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050912
subclass of: prothoracic leg sensillum
subclass of: FBbt_00007409
subclass of: FBbt_00048079
definition: Spine shaped gustatory bristle, between 12-45 micrometres long, found on the prothoracic (1st) leg of the adult. There are approximately 37 of these bristles per female prothoracic leg, and 50 per male prothoracic leg (Stocker, 1994).
database_cross_reference: VFB:FBbt_00004253
has exact synonym: 1st leg gustatory bristle
has exact synonym: 1st leg taste bristle
has exact synonym: prothoracic leg gustatory bristle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004253
in subset: cur

Axiom
annotated source: prothoracic leg taste bristle
annotated property: definition
annotated target: Spine shaped gustatory bristle, between 12-45 micrometres long, found on the prothoracic (1st) leg of the adult. There are approximately 37 of these bristles per female prothoracic leg, and 50 per male prothoracic leg (Stocker, 1994).
database_cross_reference: FlyBase:FBrf0049501
database_cross_reference: FlyBase:FBrf0068700

adult mesothoracic sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007239
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: adult thoracic sensillum
subclass of: Restriction
  on property: part of
  some values from: adult mesothoracic segment
definition: Any adult sensillum (FBbt:00007239) that is part of some mesothoracic segment (FBbt:00000018).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004297
in subset: cur

Axiom
annotated source: adult mesothoracic sensillum
annotated property: definition
annotated target: Any adult sensillum (FBbt:00007239) that is part of some mesothoracic segment (FBbt:00000018).
database_cross_reference: FBC:Autogenerated

mesothoracic bristle
type: Class
equivalent class: Class
  intersection of: chaeta
  intersection of: Restriction
    on property: part of
    some values from: adult mesothoracic segment
subclass of: adult mesothoracic sensillum
subclass of: chaeta
definition: Any chaeta found in the mesothoracic segment of the adult.
database_cross_reference: VFB:FBbt_00004298
has exact synonym: mesothoracic chaeta
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004298
in subset: cur

Axiom
annotated source: mesothoracic bristle
annotated property: definition
annotated target: Any chaeta found in the mesothoracic segment of the adult.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

mesothoracic leg sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic leg
subclass of: leg sensillum
subclass of: adult mesothoracic sensillum
subclass of: Restriction
  on property: part of
  some values from: mesothoracic leg
definition: Any sensillum (FBbt:00007152) that is part of some mesothoracic leg (FBbt:00004685).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004362
in subset: cur

Axiom
annotated source: mesothoracic leg sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some mesothoracic leg (FBbt:00004685).
database_cross_reference: FBC:Autogenerated

mesothoracic leg taste bristle
type: Class
equivalent class: Class
  intersection of: chaeta
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic leg
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050912
subclass of: mesothoracic bristle
subclass of: mesothoracic leg sensillum
subclass of: FBbt_00007409
definition: Spine shaped gustatory bristle, between 12-45 micrometres long, found on the mesothoracic (2nd) leg of the adult. There are approximately 30 of these bristles per mesothoracic leg.
database_cross_reference: VFB:FBbt_00004363
has exact synonym: 2nd leg gustatory bristle
has exact synonym: 2nd leg taste bristle
has exact synonym: mesothoracic leg gustatory bristle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004363
in subset: cur

Axiom
annotated source: mesothoracic leg taste bristle
annotated property: definition
annotated target: Spine shaped gustatory bristle, between 12-45 micrometres long, found on the mesothoracic (2nd) leg of the adult. There are approximately 30 of these bristles per mesothoracic leg.
database_cross_reference: FlyBase:FBrf0049501
database_cross_reference: FlyBase:FBrf0068700

adult metathoracic sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007239
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: adult thoracic sensillum
subclass of: Restriction
  on property: part of
  some values from: adult metathoracic segment
definition: Any adult sensillum (FBbt:00007239) that is part of some metathoracic segment (FBbt:00000019).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004407
in subset: cur

Axiom
annotated source: adult metathoracic sensillum
annotated property: definition
annotated target: Any adult sensillum (FBbt:00007239) that is part of some metathoracic segment (FBbt:00000019).
database_cross_reference: FBC:Autogenerated

metathoracic bristle
type: Class
equivalent class: Class
  intersection of: chaeta
  intersection of: Restriction
    on property: part of
    some values from: adult metathoracic segment
subclass of: adult metathoracic sensillum
subclass of: chaeta
definition: Any chaeta found in the metathoracic segment of the adult.
database_cross_reference: VFB:FBbt_00004408
has exact synonym: metathoracic chaeta
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004408
in subset: cur

Axiom
annotated source: metathoracic bristle
annotated property: definition
annotated target: Any chaeta found in the metathoracic segment of the adult.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

metathoracic leg sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: metathoracic leg
subclass of: leg sensillum
subclass of: adult metathoracic sensillum
subclass of: Restriction
  on property: part of
  some values from: metathoracic leg
definition: Any sensillum (FBbt:00007152) that is part of some metathoracic leg (FBbt:00004707).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004420
in subset: cur

Axiom
annotated source: metathoracic leg sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some metathoracic leg (FBbt:00004707).
database_cross_reference: FBC:Autogenerated

metathoracic leg taste bristle
type: Class
equivalent class: Class
  intersection of: chaeta
  intersection of: Restriction
    on property: part of
    some values from: metathoracic leg
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050912
subclass of: metathoracic bristle
subclass of: metathoracic leg sensillum
subclass of: FBbt_00007409
definition: Spine shaped gustatory bristle, between 12-45 micrometres long, found on the metathoracic (3rd) leg of the adult. There are approximately 31-32 of these bristles per metathoracic leg.
database_cross_reference: VFB:FBbt_00004421
has exact synonym: 3rd leg gustatory bristle
has exact synonym: 3rd leg taste bristle
has exact synonym: metathoracic leg gustatory bristle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004421
in subset: cur

Axiom
annotated source: metathoracic leg taste bristle
annotated property: definition
annotated target: Spine shaped gustatory bristle, between 12-45 micrometres long, found on the metathoracic (3rd) leg of the adult. There are approximately 31-32 of these bristles per metathoracic leg.
database_cross_reference: FlyBase:FBrf0049501
database_cross_reference: FlyBase:FBrf0068700

late extended germ band embryo
type: Class
subclass of: extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00014201
definition: A collective term for stages 11 and 12.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004450
in subset: cur

Axiom
annotated source: late extended germ band embryo
annotated property: definition
annotated target: A collective term for stages 11 and 12.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult abdominal sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: adult abdomen
subclass of: FBbt_00007239
subclass of: Restriction
  on property: part of
  some values from: adult abdomen
definition: Sensillum of the adult abdomen.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004461
in subset: cur

Axiom
annotated source: adult abdominal sensillum
annotated property: definition
annotated target: Sensillum of the adult abdomen.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

female terminalia sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: female terminalia
subclass of: adult abdominal sensillum
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: female terminalia
definition: Any sensillum (FBbt:00007152) that is part of some female terminalia (FBbt:00004830).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004465
in subset: cur

Axiom
annotated source: female terminalia sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some female terminalia (FBbt:00004830).
database_cross_reference: FBC:Autogenerated

male terminalia sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: male terminalia
subclass of: adult abdominal sensillum
subclass of: FBbt_00048490
subclass of: Restriction
  on property: part of
  some values from: male terminalia
definition: Any sensillum (FBbt:00007152) that is part of some male terminalia (FBbt:00004835).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004469
in subset: cur

Axiom
annotated source: male terminalia sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some male terminalia (FBbt:00004835).
database_cross_reference: FBC:Autogenerated

sclerite
type: Class
subclass of: FBbt_00007284
definition: A region of integument whose external cuticular part is a hard, sclerotized plate.
has alternative id: FBbt:00007287
database_cross_reference: UBERON:6004475
has exact synonym: integumentary plate
has OBO namespace: fly_anatomy.ontology
has related synonym: plate
id: FBbt:00004475
in subset: FB gloss
in subset: cur

Axiom
annotated source: sclerite
annotated property: definition
annotated target: A region of integument whose external cuticular part is a hard, sclerotized plate.
database_cross_reference: FBC:GG

abdominal tergite
type: Class
subclass of: sclerite
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: adult abdominal segment
subclass of: Restriction
  on property: part of
  some values from: adult external abdomen
subclass of: Restriction
  on property: develops from
  some values from: anterior dorsal histoblast nest abdominal
subclass of: Restriction
  on property: develops from
  some values from: posterior dorsal histoblast nest abdominal
definition: The dorsal plate (sclerite) of an adult abdominal segment.
has alternative id: FBbt:00004789
database_cross_reference: UBERON:6004476
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004476
in subset: FB gloss
in subset: cur

Axiom
annotated source: abdominal tergite
annotated property: definition
annotated target: The dorsal plate (sclerite) of an adult abdominal segment.
database_cross_reference: FlyBase:FBrf0007734
database_cross_reference: FlyBase:FBrf0111704

adult external head
type: Class
subclass of: FBbt_00007289
subclass of: Restriction
  on property: part of
  some values from: adult head
subclass of: Restriction
  on property: part of
  some values from: adult integumentary system
definition: The external integumentary structures that make up the surface of the adult head.
database_cross_reference: UBERON:6004481
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004481
in subset: cur

Axiom
annotated source: adult external head
annotated property: definition
annotated target: The external integumentary structures that make up the surface of the adult head.
database_cross_reference: FlyBase:FBrf0007734

adult head capsule
type: Class
subclass of: FBbt_00007284
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult external head
subclass of: Restriction
  on property: develops from
  some values from: eye-antennal disc
definition: The fused, compact cephalic plates that comprise the adult head, excluding the eyes, antennae and mouthparts.
database_cross_reference: UBERON:0003153
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has exact synonym: capsula
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004482
in subset: FB gloss
in subset: cur

Axiom
annotated source: adult head capsule
annotated property: definition
annotated target: The fused, compact cephalic plates that comprise the adult head, excluding the eyes, antennae and mouthparts.
database_cross_reference: FlyBase:FBrf0166419

Axiom
annotated source: adult head capsule
annotated property: hasExactSynonym
annotated target: capsula
database_cross_reference: FlyBase:FBrf0166419

ocellar triangle
type: Class
subclass of: FBbt_00007284
subclass of: Restriction
  on property: part of
  some values from: FBbt_00053239
definition: Region of the integument of the medial part of the vertex of the adult head, where the ocelli are located (Ferris, 1950). It has a smooth surface, in contrast to the surrounding cuticle (Ferris, 1950).
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has exact synonym: IOC
has exact synonym: interocellar cuticle
has exact synonym: vertical triangle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004495
in subset: cur
comment: The ocellar triangle does not correspond to a separate sclerite (Ferris, 1950).

Axiom
annotated source: ocellar triangle
annotated property: definition
annotated target: Region of the integument of the medial part of the vertex of the adult head, where the ocelli are located (Ferris, 1950). It has a smooth surface, in contrast to the surrounding cuticle (Ferris, 1950).
database_cross_reference: FlyBase:FBrf0007734

Axiom
annotated source: ocellar triangle
annotated property: hasExactSynonym
annotated target: IOC
database_cross_reference: FlyBase:FBrf0229329

Axiom
annotated source: ocellar triangle
annotated property: hasExactSynonym
annotated target: interocellar cuticle
database_cross_reference: FlyBase:FBrf0229329

Axiom
annotated source: ocellar triangle
annotated property: hasExactSynonym
annotated target: vertical triangle
database_cross_reference: FlyBase:FBrf0007734

ocellus
type: Class
subclass of: photoreceptor
subclass of: FBbt_00007231
subclass of: FBbt_00007241
subclass of: Restriction
  on property: part of
  some values from: ocellar triangle
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110844
subclass of: Restriction
  on property: capable of
  some values from: GO_0050908
definition: A simple visual organ on the top of the adult head (Jean-Guillaume and Kumar, 2022). There are three of these per head, arranged in a triangle with one on the midline and the others slightly posterior and lateral (Jean-Guillaume and Kumar, 2022). They develop from the eye discs (Jean-Guillaume and Kumar, 2022).
database_cross_reference: UBERON:0003161
database_cross_reference: VFB:FBbt_00004505
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004505
in subset: FB gloss
in subset: cur

Axiom
annotated source: ocellus
annotated property: definition
annotated target: A simple visual organ on the top of the adult head (Jean-Guillaume and Kumar, 2022). There are three of these per head, arranged in a triangle with one on the midline and the others slightly posterior and lateral (Jean-Guillaume and Kumar, 2022). They develop from the eye discs (Jean-Guillaume and Kumar, 2022).
database_cross_reference: FlyBase:FBrf0166419
database_cross_reference: FlyBase:FBrf0255165

eye
type: Class
subclass of: adult sense organ
subclass of: photoreceptor
subclass of: FBbt_00007235
subclass of: FBbt_00025991
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult head
subclass of: Restriction
  on property: develops from
  some values from: eye disc
subclass of: Restriction
  on property: capable of
  some values from: GO_0050908
definition: A bilaterally paired compound sense organ of the adult head that functions in visual perception.
database_cross_reference: UBERON:0000018
database_cross_reference: VFB:FBbt_00004508
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
has related synonym: compound eye
id: FBbt:00004508
in subset: FB gloss
in subset: cur

Axiom
annotated source: eye
annotated property: definition
annotated target: A bilaterally paired compound sense organ of the adult head that functions in visual perception.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ommatidium
type: Class
subclass of: photoreceptor
subclass of: FBbt_00007231
subclass of: FBbt_00007241
subclass of: Restriction
  on property: part of
  some values from: retina
subclass of: Restriction
  on property: develops from
  some values from: ommatidial precursor cluster
subclass of: Restriction
  on property: capable of
  some values from: GO_0050908
definition: One of the facets of the compound eye. It is composed of eight light-sensing photoreceptor cells (photoreceptor cell R1-R8) and accessory cells. There are around 800 ommatidia in each compound eye.
database_cross_reference: UBERON:0000971
database_cross_reference: VFB:FBbt_00004510
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004510
in subset: FB gloss
in subset: cur

Axiom
annotated source: ommatidium
annotated property: definition
annotated target: One of the facets of the compound eye. It is composed of eight light-sensing photoreceptor cells (photoreceptor cell R1-R8) and accessory cells. There are around 800 ommatidia in each compound eye.
database_cross_reference: FlyBase:FBrf0166419
database_cross_reference: FlyBase:FBrf0180690

antenna
type: Class
subclass of: appendage
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult antennal segment
subclass of: Restriction
  on property: part of
  some values from: adult external head
subclass of: Restriction
  on property: develops from
  some values from: antennal disc
definition: Paired, segmented, jointed, sensory appendage attached to the anterior of the head capsule, between the eyes.
database_cross_reference: UBERON:0000972
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004511
in subset: FB gloss
in subset: cur

Axiom
annotated source: antenna
annotated property: definition
annotated target: Paired, segmented, jointed, sensory appendage attached to the anterior of the head capsule, between the eyes.
database_cross_reference: FlyBase:FBrf0007734

second segment of antenna
type: Class
subclass of: segment of antenna
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110813
definition: Second segment of the antenna located ventrolaterally to the first segment. It is larger than the first segment and somewhat swollen. It has on average 25 bristles of various sizes. The Johnston's organ is contained in this segment.
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has exact synonym: antennal segment 2
has exact synonym: pedicel
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004514
in subset: cur

Axiom
annotated source: second segment of antenna
annotated property: definition
annotated target: Second segment of the antenna located ventrolaterally to the first segment. It is larger than the first segment and somewhat swollen. It has on average 25 bristles of various sizes. The Johnston's organ is contained in this segment.
database_cross_reference: FlyBase:FBrf0007734
database_cross_reference: FlyBase:FBrf0031004

Axiom
annotated source: second segment of antenna
annotated property: hasExactSynonym
annotated target: pedicel
database_cross_reference: FlyBase:FBrf0007734

neck
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: part of
  some values from: adult prothoracic segment
definition: Structure connecting the head to the body, through which the esophagus, cervical connective, two salivary gland ducts, two tracheal trunks and two stomodeal nerves pass.
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004550
in subset: cur

Axiom
annotated source: neck
annotated property: definition
annotated target: Structure connecting the head to the body, through which the esophagus, cervical connective, two salivary gland ducts, two tracheal trunks and two stomodeal nerves pass.
database_cross_reference: FlyBase:FBrf0007734

adult external thorax
type: Class
subclass of: FBbt_00007289
subclass of: Restriction
  on property: part of
  some values from: adult thorax
subclass of: Restriction
  on property: part of
  some values from: adult integumentary system
definition: The external integumentary structures that make up the surface of the adult thorax.
database_cross_reference: UBERON:6004551
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004551
in subset: cur

Axiom
annotated source: adult external thorax
annotated property: definition
annotated target: The external integumentary structures that make up the surface of the adult thorax.
database_cross_reference: FlyBase:FBrf0007734

leg
type: Class
subclass of: appendage
subclass of: Restriction
  on property: part of
  some values from: adult thoracic segment
subclass of: Restriction
  on property: part of
  some values from: adult external thorax
definition: The walking appendages of each segment of the ventral adult external thorax.
database_cross_reference: UBERON:0005895
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004640
in subset: FB gloss
in subset: cur

Axiom
annotated source: leg
annotated property: definition
annotated target: The walking appendages of each segment of the ventral adult external thorax.
database_cross_reference: FBC:GG

prothoracic leg
type: Class
equivalent class: Class
  intersection of: leg
  intersection of: Restriction
    on property: part of
    some values from: prothoracic segment
subclass of: leg
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult prothoracic segment
subclass of: Restriction
  on property: develops from
  some values from: prothoracic leg disc
definition: Leg of the prothoracic segment.
database_cross_reference: UBERON:6004663
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has exact synonym: T1 leg
has exact synonym: first leg
has exact synonym: foreleg
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004663
in subset: cur

Axiom
annotated source: prothoracic leg
annotated property: definition
annotated target: Leg of the prothoracic segment.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

mesothoracic leg
type: Class
equivalent class: Class
  intersection of: leg
  intersection of: Restriction
    on property: part of
    some values from: mesothoracic segment
subclass of: leg
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult mesothoracic segment
subclass of: Restriction
  on property: develops from
  some values from: mesothoracic leg disc
definition: Leg of the mesothoracic segment.
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has exact synonym: T2 leg
has exact synonym: middle leg
has exact synonym: midleg
has exact synonym: second leg
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004685
in subset: cur

Axiom
annotated source: mesothoracic leg
annotated property: definition
annotated target: Leg of the mesothoracic segment.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

metathoracic leg
type: Class
equivalent class: Class
  intersection of: leg
  intersection of: Restriction
    on property: part of
    some values from: metathoracic segment
subclass of: leg
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult metathoracic segment
subclass of: Restriction
  on property: develops from
  some values from: metathoracic leg disc
definition: Leg of the metathoracic segment.
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has exact synonym: T3 leg
has exact synonym: hindleg
has exact synonym: third leg
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004707
in subset: cur

Axiom
annotated source: metathoracic leg
annotated property: definition
annotated target: Leg of the metathoracic segment.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult external abdomen
type: Class
subclass of: FBbt_00007289
subclass of: Restriction
  on property: part of
  some values from: adult abdomen
subclass of: Restriction
  on property: part of
  some values from: adult integumentary system
definition: The external integumentary structures that make up the surface of the adult abdomen.
database_cross_reference: UBERON:6004788
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004788
in subset: cur

Axiom
annotated source: adult external abdomen
annotated property: definition
annotated target: The external integumentary structures that make up the surface of the adult abdomen.
database_cross_reference: FlyBase:FBrf0007734

abdominal tergite 6
type: Class
equivalent class: Class
  intersection of: abdominal tergite
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 6
subclass of: abdominal tergite
subclass of: Restriction
  on property: part of
  some values from: adult abdominal segment 6
subclass of: Restriction
  on property: develops from
  some values from: anterior dorsal histoblast nest abdominal 6
subclass of: Restriction
  on property: develops from
  some values from: posterior dorsal histoblast nest abdominal 6
definition: Any abdominal tergite (FBbt:00004476) that is part of some abdominal segment 6 (FBbt:00000027).
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004795
in subset: cur

Axiom
annotated source: abdominal tergite 6
annotated property: definition
annotated target: Any abdominal tergite (FBbt:00004476) that is part of some abdominal segment 6 (FBbt:00000027).
database_cross_reference: FBC:Autogenerated

abdominal tergite 8
type: Class
equivalent class: Class
  intersection of: abdominal tergite
  intersection of: Restriction
    on property: part of
    some values from: abdominal segment 8
subclass of: abdominal tergite
subclass of: Restriction
  on property: part of
  some values from: adult abdominal segment 8
subclass of: Restriction
  on property: part of
  some values from: terminalia
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052052
definition: Tergite of adult abdominal segment 8. It is sexually dimorphic.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004797
in subset: cur

Axiom
annotated source: abdominal tergite 8
annotated property: definition
annotated target: Tergite of adult abdominal segment 8. It is sexually dimorphic.
database_cross_reference: FlyBase:FBrf0007734
database_cross_reference: FlyBase:FBrf0031004

genitalia
type: Class
subclass of: anatomical structure
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: terminalia
subclass of: Restriction
  on property: develops from
  some values from: genital disc
definition: A collective name for the external and internal organs directly participating in the propagation of the species.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004826
in subset: FB gloss
in subset: cur

Axiom
annotated source: genitalia
annotated property: definition
annotated target: A collective name for the external and internal organs directly participating in the propagation of the species.
database_cross_reference: FlyBase:FBrf0166419

female genitalia
type: Class
subclass of: genitalia
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: female terminalia
subclass of: Restriction
  on property: develops from
  some values from: female genital disc
definition: Set of internal and external structures, originating from abdominal segments 8 and 9, that makes up the genital apparatus (McQueen et al., 2022). It develops from the female genital-primordium part of the genital disc (McQueen et al., 2022).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004827
in subset: cur

Axiom
annotated source: female genitalia
annotated property: definition
annotated target: Set of internal and external structures, originating from abdominal segments 8 and 9, that makes up the genital apparatus (McQueen et al., 2022). It develops from the female genital-primordium part of the genital disc (McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0137175
database_cross_reference: FlyBase:FBrf0253444

male genitalia
type: Class
subclass of: genitalia
subclass of: FBbt_00048490
subclass of: Restriction
  on property: part of
  some values from: male terminalia
subclass of: Restriction
  on property: develops from
  some values from: male genital disc
definition: Set of internal and external structures originating from segments 8-9, that makes up the genital apparatus (Rice et al., 2019). It develops from the male genital disc (Rice et al., 2019).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004828
in subset: cur

Axiom
annotated source: male genitalia
annotated property: definition
annotated target: Set of internal and external structures originating from segments 8-9, that makes up the genital apparatus (Rice et al., 2019). It develops from the male genital disc (Rice et al., 2019).
database_cross_reference: FlyBase:FBrf0137175
database_cross_reference: FlyBase:FBrf0244105

terminalia
type: Class
subclass of: anatomical structure
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult abdomen
subclass of: Restriction
  on property: develops from
  some values from: genital disc
definition: The entire set of internal and external structures of the genitalia and analia in the distal half of the abdomen, i.e. segments 8-10 (Rice et al., 2019; McQueen et al., 2022). It develops from the genital disc (Rice et al., 2019; McQueen et al., 2022).
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004829
in subset: FB gloss
in subset: cur

Axiom
annotated source: terminalia
annotated property: definition
annotated target: The entire set of internal and external structures of the genitalia and analia in the distal half of the abdomen, i.e. segments 8-10 (Rice et al., 2019; McQueen et al., 2022). It develops from the genital disc (Rice et al., 2019; McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0137175
database_cross_reference: FlyBase:FBrf0166419
database_cross_reference: FlyBase:FBrf0244105
database_cross_reference: FlyBase:FBrf0253444

female terminalia
type: Class
subclass of: terminalia
subclass of: FBbt_00048491
subclass of: Restriction
  on property: develops from
  some values from: female genital disc
definition: The entire set of internal and external structures in the distal half of the female abdomen, i.e. abdominal segments 8-10, that makes up the female genitalia and female analia (McQueen et al., 2022). It develops from the female genital disc (McQueen et al., 2022).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004830
in subset: cur

Axiom
annotated source: female terminalia
annotated property: definition
annotated target: The entire set of internal and external structures in the distal half of the female abdomen, i.e. abdominal segments 8-10, that makes up the female genitalia and female analia (McQueen et al., 2022). It develops from the female genital disc (McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0031004
database_cross_reference: FlyBase:FBrf0253444

male terminalia
type: Class
subclass of: terminalia
subclass of: FBbt_00048490
subclass of: Restriction
  on property: develops from
  some values from: male genital disc
definition: The entire set of external structures in the distal half of the male abdomen, i.e. abdominal segments 8-10, that makes up the male genitalia and male analia (Rice et al., 2019). It develops from the male genital disc (Rice et al., 2019).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004835
in subset: cur

Axiom
annotated source: male terminalia
annotated property: definition
annotated target: The entire set of external structures in the distal half of the male abdomen, i.e. abdominal segments 8-10, that makes up the male genitalia and male analia (Rice et al., 2019). It develops from the male genital disc (Rice et al., 2019).
database_cross_reference: FlyBase:FBrf0031004
database_cross_reference: FlyBase:FBrf0244105

epandrium
type: Class
subclass of: abdominal tergite
subclass of: FBbt_00048388
subclass of: Restriction
  on property: part of
  some values from: adult abdominal segment 9
subclass of: Restriction
  on property: part of
  some values from: male genitalia
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110675
definition: Horseshoe-shaped tergite which, dorsally, surrounds the male cerci. It contains about 30 epandrial bristles on each side. The left and right sides of the epandrium are connected by the subepandrial sclerite. The ventral part of each side of the epandrium is divided into an epandrial ventral lobe and an epandrial posterior lobe.
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has exact synonym: abdominal tergite 9
has exact synonym: genital arch
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004839
in subset: cur

Axiom
annotated source: epandrium
annotated property: definition
annotated target: Horseshoe-shaped tergite which, dorsally, surrounds the male cerci. It contains about 30 epandrial bristles on each side. The left and right sides of the epandrium are connected by the subepandrial sclerite. The ventral part of each side of the epandrium is divided into an epandrial ventral lobe and an epandrial posterior lobe.
database_cross_reference: FlyBase:FBrf0029539
database_cross_reference: FlyBase:FBrf0244105

Axiom
annotated source: epandrium
annotated property: hasExactSynonym
annotated target: abdominal tergite 9
database_cross_reference: FlyBase:FBrf0007734
database_cross_reference: FlyBase:FBrf0244105

Axiom
annotated source: epandrium
annotated property: hasExactSynonym
annotated target: genital arch
database_cross_reference: FlyBase:FBrf0244105

organ system
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: organism
definition: A division of the whole organism into specialized systems.
database_cross_reference: UBERON:0000467
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004856
in subset: cur

Axiom
annotated source: organ system
annotated property: definition
annotated target: A division of the whole organism into specialized systems.
database_cross_reference: FBC:GG

reproductive system
type: Class
subclass of: organ system
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0002451
definition: System comprising the internal and external anatomy required for production of gametes and fertilization. It is sexually dimorphic.
database_cross_reference: UBERON:0000990
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004857
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: reproductive system
annotated property: definition
annotated target: System comprising the internal and external anatomy required for production of gametes and fertilization. It is sexually dimorphic.
database_cross_reference: FlyBase:FBrf0007735

gonad
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: reproductive system
definition: The organ of the reproductive system in which the germ cells reside.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004858
in subset: FB gloss
in subset: cur

Axiom
annotated source: gonad
annotated property: definition
annotated target: The organ of the reproductive system in which the germ cells reside.
database_cross_reference: FBC:GG

gonadal sheath
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: gonad
definition: Thin covering of the gonads, containing one or more epithelial layers and a muscle layer.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004859
in subset: cur

Axiom
annotated source: gonadal sheath
annotated property: definition
annotated target: Thin covering of the gonads, containing one or more epithelial layers and a muscle layer.
database_cross_reference: FlyBase:FBrf0064777

germline cell
type: Class
subclass of: cell
definition: Cell that can contribute DNA to the next generation. It is or may become a gamete.
has OBO namespace: fly_anatomy.ontology
has related synonym: germ cell
id: FBbt:00004860
in subset: cur

Axiom
annotated source: germline cell
annotated property: definition
annotated target: Cell that can contribute DNA to the next generation. It is or may become a gamete.
database_cross_reference: FlyBase:FBrf0101973
database_cross_reference: FlyBase:FBrf0216027

germline stem cell
type: Class
subclass of: germline cell
subclass of: stem cell
subclass of: Restriction
  on property: develops from
  some values from: primordial germ cell
definition: Stem cell that is the precursor of gametes.
database_cross_reference: CL:0000014
has exact synonym: GSC
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004861
in subset: cur

Axiom
annotated source: germline stem cell
annotated property: definition
annotated target: Stem cell that is the precursor of gametes.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: germline stem cell
annotated property: hasExactSynonym
annotated target: GSC
database_cross_reference: FlyBase:FBrf0219716

female reproductive system
type: Class
equivalent class: Class
  intersection of: reproductive system
  intersection of: Restriction
    on property: part of
    some values from: female organism
subclass of: reproductive system
subclass of: FBbt_00048491
definition: Any reproductive system (FBbt:00004857) that is part of some female organism (FBbt:00007011).
database_cross_reference: UBERON:0000474
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004864
in subset: cur

Axiom
annotated source: female reproductive system
annotated property: definition
annotated target: Any reproductive system (FBbt:00004857) that is part of some female organism (FBbt:00007011).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0034074

ovary
type: Class
subclass of: gonad
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: adult
subclass of: Restriction
  on property: part of
  some values from: female reproductive system
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048539
definition: Female gonad. It contains about 16-20 ovarioles.
database_cross_reference: UBERON:0000992
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004865
in subset: RD
in subset: cur

Axiom
annotated source: ovary
annotated property: definition
annotated target: Female gonad. It contains about 16-20 ovarioles.
database_cross_reference: FlyBase:FBrf0064777
database_cross_reference: FlyBase:FBrf0221547

germarium
type: Class
subclass of: multi-tissue structure
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: ovariole
definition: Anterior region of the ovariole, that is connected to posterior egg chambers.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004866
in subset: RD
in subset: cur

Axiom
annotated source: germarium
annotated property: definition
annotated target: Anterior region of the ovariole, that is connected to posterior egg chambers.
database_cross_reference: FlyBase:FBrf0064777

germarium region 1
type: Class
subclass of: portion of tissue
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: germarium
definition: Anterior region of the germarium where cysts start developing.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004867
in subset: RD
in subset: cur

Axiom
annotated source: germarium region 1
annotated property: definition
annotated target: Anterior region of the germarium where cysts start developing.
database_cross_reference: FlyBase:FBrf0064777

female germline stem cell
type: Class
subclass of: germline stem cell
subclass of: Restriction
  on property: part of
  some values from: germarium region 1
definition: Female germline cell and stem cell from which all other female germline cells develop. Each of its divisions gives rise to one cystoblast and one female germline stem cell.
database_cross_reference: CL:0000022
has exact synonym: female GSC
has exact synonym: oogonial cell
has exact synonym: oogonium
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004873
in subset: RD
in subset: cur

Axiom
annotated source: female germline stem cell
annotated property: definition
annotated target: Female germline cell and stem cell from which all other female germline cells develop. Each of its divisions gives rise to one cystoblast and one female germline stem cell.
database_cross_reference: FlyBase:FBrf0017959
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: female germline stem cell
annotated property: hasExactSynonym
annotated target: female GSC
database_cross_reference: FlyBase:FBrf0219716

Axiom
annotated source: female germline stem cell
annotated property: hasExactSynonym
annotated target: oogonial cell
database_cross_reference: FlyBase:FBrf0021038

germline cyst
type: Class
subclass of: multi-tissue structure
definition: A developing unit of gametogenesis consisting of germline cells encapsulated by a layer of somatic cells.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004875
in subset: cur

Axiom
annotated source: germline cyst
annotated property: definition
annotated target: A developing unit of gametogenesis consisting of germline cells encapsulated by a layer of somatic cells.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

cystoblast
type: Class
subclass of: FBbt_00057012
subclass of: Restriction
  on property: part of
  some values from: germarium
subclass of: Restriction
  on property: develops from
  some values from: female germline stem cell
definition: Female germline cell which is the daughter of a female germline stem cell. It is found in region 1 of the germarium. It divides four times to give rise to 16 daughter cyst cells, which together form a germline cyst. Division is through a cleavage-like process, with the daughter cells being smaller than the parent cystoblast.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004876
in subset: RD
in subset: cur

Axiom
annotated source: cystoblast
annotated property: definition
annotated target: Female germline cell which is the daughter of a female germline stem cell. It is found in region 1 of the germarium. It divides four times to give rise to 16 daughter cyst cells, which together form a germline cyst. Division is through a cleavage-like process, with the daughter cells being smaller than the parent cystoblast.
database_cross_reference: FlyBase:FBrf0064777

cyst cell of ovary
type: Class
subclass of: FBbt_00057012
subclass of: Restriction
  on property: part of
  some values from: female germline cyst
subclass of: Restriction
  on property: develops from
  some values from: cystoblast
definition: Female germline cell born during one of four rapid rounds of cell division following the birth of a cystoblast from a female germline stem cell until the point where one of the resulting 16 cells (the presumptive oocyte) enters meiosis. Cyst cells are interconnected by ring canals, resulting from incomplete cytokinesis during cell division. The oocyte develops from one of the two cyst cells that have connections to four other cyst cells, the other 15 cyst cells differentiate into nurse cells.
has broad synonym: cyst cell
has exact synonym: cystocyte
has exact synonym: germarial cystocyte
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004877
in subset: RD
in subset: cur

Axiom
annotated source: cyst cell of ovary
annotated property: definition
annotated target: Female germline cell born during one of four rapid rounds of cell division following the birth of a cystoblast from a female germline stem cell until the point where one of the resulting 16 cells (the presumptive oocyte) enters meiosis. Cyst cells are interconnected by ring canals, resulting from incomplete cytokinesis during cell division. The oocyte develops from one of the two cyst cells that have connections to four other cyst cells, the other 15 cyst cells differentiate into nurse cells.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0064777

Axiom
annotated source: cyst cell of ovary
annotated property: hasExactSynonym
annotated target: cystocyte
database_cross_reference: FlyBase:FBrf0064777

Axiom
annotated source: cyst cell of ovary
annotated property: hasExactSynonym
annotated target: germarial cystocyte
database_cross_reference: FlyBase:FBrf0021038

oocyte
type: Class
subclass of: FBbt_00057012
subclass of: Restriction
  on property: part of
  some values from: egg chamber
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00014874
definition: Female germline cell that develops from one of the 16 cyst cells (the presumptive oocyte) produced by a cystoblast. It matures in an egg chamber of the ovariole and will be released from the ovary as an egg.
database_cross_reference: CL:0000023
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004886
in subset: RD
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: oocyte
annotated property: definition
annotated target: Female germline cell that develops from one of the 16 cyst cells (the presumptive oocyte) produced by a cystoblast. It matures in an egg chamber of the ovariole and will be released from the ovary as an egg.
database_cross_reference: FlyBase:FBrf0021038

pole plasm
type: Class
subclass of: cell component
subclass of: Restriction
  on property: part of
  some values from: egg
subclass of: Restriction
  on property: part of
  some values from: oocyte
subclass of: Restriction
  on property: part of
  some values from: pre-blastoderm embryo
definition: Specialized region of the posterior egg/embryo cytoplasm characterized by the presence of non-membrane limited electron dense bodies (polar granules) (Okada, 1998).
has narrow synonym: germ plasm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004891
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: pole plasm
annotated property: definition
annotated target: Specialized region of the posterior egg/embryo cytoplasm characterized by the presence of non-membrane limited electron dense bodies (polar granules) (Okada, 1998).
database_cross_reference: FlyBase:FBrf0064781
database_cross_reference: FlyBase:FBrf0101973

Axiom
annotated source: pole plasm
annotated property: hasNarrowSynonym
annotated target: germ plasm
database_cross_reference: FlyBase:FBrf0101973

ovariole
type: Class
subclass of: FBbt_00048491
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: ovary
definition: An egg assembly line. Consists of a germarium at the anterior tip connected to a chain of egg chambers, each one more mature than the preceding, more anterior egg chamber in the chain. Each ovariole is encased in an ovarian sheath. A typical ovary contains about 16 ovarioles.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004893
in subset: RD
in subset: cur
comment: DISAMBIGUATION: The term ovariole is sometimes incorrectly used to refer to individual egg chambers. Please use the term 'egg chamber' for this.

Axiom
annotated source: ovariole
annotated property: definition
annotated target: An egg assembly line. Consists of a germarium at the anterior tip connected to a chain of egg chambers, each one more mature than the preceding, more anterior egg chamber in the chain. Each ovariole is encased in an ovarian sheath. A typical ovary contains about 16 ovarioles.
database_cross_reference: FlyBase:FBrf0064777

egg chamber
type: Class
subclass of: female germline cyst
definition: Female germline cyst that forms as the 16-cell cyst moves posteriorly through the germarium, becoming encapsulated in follicle cells (Spradling, 1993). Its formation is completed in germarium region 3, where it buds off from the germarium and progresses posteriorly along the ovariole (Spradling, 1993, Reichmann and Ephrussi, 2001).
database_cross_reference: UBERON:0003199
has exact synonym: follicle
has exact synonym: germarium derived egg chamber
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004894
in subset: FB gloss
in subset: RD
in subset: cur

Axiom
annotated source: egg chamber
annotated property: definition
annotated target: Female germline cyst that forms as the 16-cell cyst moves posteriorly through the germarium, becoming encapsulated in follicle cells (Spradling, 1993). Its formation is completed in germarium region 3, where it buds off from the germarium and progresses posteriorly along the ovariole (Spradling, 1993, Reichmann and Ephrussi, 2001).
database_cross_reference: FlyBase:FBrf0064777

Axiom
annotated source: egg chamber
annotated property: hasExactSynonym
annotated target: follicle
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: egg chamber
annotated property: hasExactSynonym
annotated target: germarium derived egg chamber
database_cross_reference: FlyBase:FBrf0089570

follicle stem cell
type: Class
subclass of: gonadal somatic stem cell
subclass of: somatic cell of ovariole
subclass of: Restriction
  on property: part of
  some values from: germarium
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048548
subclass of: Restriction
  on property: expresses
  some values from: FBgn0000636
subclass of: Restriction
  on property: expresses
  some values from: FBgn0004606
subclass of: Restriction
  on property: expresses
  some values from: FBgn0010453
definition: Stem cell from which the follicle cells that envelop the germline cyst derive. They develop from the larval follicle stem cell progenitors (Slaidina et al., 2020). There are two follicle stem cells in each germarium, located at opposite sides of the lateral wall of the germarium, in between regions 2a and 2b (Reilein et al., 2017). Each follicle stem cell produces over 500 follicle cells from nine cell divisions (Airoldi et al., 2011).
has broad synonym: SSC
has broad synonym: somatic stem cell
database_cross_reference: CL:0000441
has exact synonym: FSC
has exact synonym: epithelial follicle stem cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004903
in subset: RD
in subset: cur
comment: Can be identified by expression of zfh1, Fas3 and low expression of Wnt4 (Rust et al., 2020).

Axiom
annotated source: follicle stem cell
annotated property: definition
annotated target: Stem cell from which the follicle cells that envelop the germline cyst derive. They develop from the larval follicle stem cell progenitors (Slaidina et al., 2020). There are two follicle stem cells in each germarium, located at opposite sides of the lateral wall of the germarium, in between regions 2a and 2b (Reilein et al., 2017). Each follicle stem cell produces over 500 follicle cells from nine cell divisions (Airoldi et al., 2011).
database_cross_reference: FlyBase:FBrf0084162
database_cross_reference: FlyBase:FBrf0202474
database_cross_reference: FlyBase:FBrf0209788
database_cross_reference: FlyBase:FBrf0217092
database_cross_reference: FlyBase:FBrf0235409
database_cross_reference: FlyBase:FBrf0244767
database_cross_reference: FlyBase:FBrf0247148

Axiom
annotated source: follicle stem cell
annotated property: hasBroadSynonym
annotated target: somatic stem cell
database_cross_reference: FlyBase:FBrf0202474

Axiom
annotated source: follicle stem cell
annotated property: hasExactSynonym
annotated target: FSC
database_cross_reference: FlyBase:FBrf0207075

Axiom
annotated source: follicle stem cell
annotated property: hasExactSynonym
annotated target: epithelial follicle stem cell
database_cross_reference: FlyBase:FBrf0207075

follicle cell
type: Class
subclass of: somatic cell of ovariole
subclass of: FBbt_00058238
subclass of: Restriction
  on property: part of
  some values from: egg chamber
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00047835
definition: One of the somatic epithelial cells that is either associated with the germline cyst to form an egg chamber or connecting the egg chambers (Jevitt et al., 2020). Some of these cells, particularly main body follicle cells, can form ring canals to connect to one another (Airoldi et al., 2011).
database_cross_reference: CL:0000477
has narrow synonym: syncytial follicle cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004904
in subset: FB gloss
in subset: RD
in subset: cur

Axiom
annotated source: follicle cell
annotated property: definition
annotated target: One of the somatic epithelial cells that is either associated with the germline cyst to form an egg chamber or connecting the egg chambers (Jevitt et al., 2020). Some of these cells, particularly main body follicle cells, can form ring canals to connect to one another (Airoldi et al., 2011).
database_cross_reference: FlyBase:FBrf0217092
database_cross_reference: FlyBase:FBrf0245616

Axiom
annotated source: follicle cell
annotated property: hasNarrowSynonym
annotated target: syncytial follicle cell
database_cross_reference: FlyBase:FBrf0217092

polar follicle cell
type: Class
subclass of: follicle cell
subclass of: Restriction
  on property: expresses
  some values from: FBgn0004956
definition: Follicle cell at the anterior or posterior pole of the egg chamber. Initially they are found in clusters of 3-8 per pole, then excess cells undergo apoptosis during stages 2-5, leaving 2 per cluster.
has exact synonym: polar cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004907
in subset: RD
in subset: cur
comment: Can be identified by expression of upd1 (Rust et al., 2020).

Axiom
annotated source: polar follicle cell
annotated property: definition
annotated target: Follicle cell at the anterior or posterior pole of the egg chamber. Initially they are found in clusters of 3-8 per pole, then excess cells undergo apoptosis during stages 2-5, leaving 2 per cluster.
database_cross_reference: FlyBase:FBrf0205319
database_cross_reference: FlyBase:FBrf0247148

Axiom
annotated source: polar follicle cell
annotated property: hasExactSynonym
annotated target: polar cell
database_cross_reference: FlyBase:FBrf0247148

oviduct
type: Class
subclass of: FBbt_00007474
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: adult
subclass of: Restriction
  on property: part of
  some values from: female reproductive system
subclass of: Restriction
  on property: continuous with
  some values from: ovary
subclass of: Restriction
  on property: continuous with
  some values from: uterus
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110692
definition: Duct of the female reproductive tract that connects the ovaries to the uterus (Hildreth, 1965; McQueen et al., 2022). The oviduct consists of two lateral oviducts (each connected to an ovary) and one common oviduct, to which the lateral oviducts connect, and which itself connects to the uterus (Hildreth, 1965; McQueen et al., 2022).
has exact synonym: female internal reproductive tract
has exact synonym: female upper reproductive tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004911
in subset: cur

Axiom
annotated source: oviduct
annotated property: definition
annotated target: Duct of the female reproductive tract that connects the ovaries to the uterus (Hildreth, 1965; McQueen et al., 2022). The oviduct consists of two lateral oviducts (each connected to an ovary) and one common oviduct, to which the lateral oviducts connect, and which itself connects to the uterus (Hildreth, 1965; McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0017075
database_cross_reference: FlyBase:FBrf0226663
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: oviduct
annotated property: hasExactSynonym
annotated target: female internal reproductive tract
database_cross_reference: FlyBase:FBrf0226663

Axiom
annotated source: oviduct
annotated property: hasExactSynonym
annotated target: female upper reproductive tract
database_cross_reference: FlyBase:FBrf0207006

lateral oviduct
type: Class
subclass of: FBbt_00007474
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: oviduct
subclass of: Restriction
  on property: continuous with
  some values from: ovary
subclass of: Restriction
  on property: continuous with
  some values from: common oviduct
definition: Epithelial tube that connects the ovary to the common oviduct (McQueen et al., 2022). It is lined with a chitinous intima, and surrounded by muscle (McQueen et al., 2022). There are two of these per organism (one per ovary) (McQueen et al., 2022). They usually have a loop near the base of the ovary in unmated females; the loop relaxes after mating to allow egg transit (Kapelnikov et al., 2008; McQueen et al., 2022).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004912
in subset: cur

Axiom
annotated source: lateral oviduct
annotated property: definition
annotated target: Epithelial tube that connects the ovary to the common oviduct (McQueen et al., 2022). It is lined with a chitinous intima, and surrounded by muscle (McQueen et al., 2022). There are two of these per organism (one per ovary) (McQueen et al., 2022). They usually have a loop near the base of the ovary in unmated females; the loop relaxes after mating to allow egg transit (Kapelnikov et al., 2008; McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0207006
database_cross_reference: FlyBase:FBrf0253444

common oviduct
type: Class
subclass of: FBbt_00007474
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: oviduct
subclass of: Restriction
  on property: continuous with
  some values from: lateral oviduct
subclass of: Restriction
  on property: continuous with
  some values from: uterus
definition: Epithelial tube that connects the lateral oviducts to the uterus (Heifetz et al., 2000; Adams and Wolfner, 2007; Kapelnikov et al., 2008; Heifetz et al., 2014; McQueen et al., 2022). It is lined with a chitinous intima, and surrounded by circular muscles (McQueen et al., 2022).
has exact synonym: main oviduct
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004913
in subset: cur

Axiom
annotated source: common oviduct
annotated property: definition
annotated target: Epithelial tube that connects the lateral oviducts to the uterus (Heifetz et al., 2000; Adams and Wolfner, 2007; Kapelnikov et al., 2008; Heifetz et al., 2014; McQueen et al., 2022). It is lined with a chitinous intima, and surrounded by circular muscles (McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0125489
database_cross_reference: FlyBase:FBrf0200717
database_cross_reference: FlyBase:FBrf0207258
database_cross_reference: FlyBase:FBrf0224569
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: common oviduct
annotated property: hasExactSynonym
annotated target: main oviduct
database_cross_reference: FlyBase:FBrf0007735

female accessory gland
type: Class
subclass of: FBbt_00048425
subclass of: Restriction
  on property: continuous with
  some values from: female accessory gland duct
subclass of: Restriction
  on property: connected to
  some values from: uterus
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110687
definition: Small, bilaterally paired gland that lies caudal to the spermathecae and is connected to the uterus by a duct (McQueen et al., 2022). The gland wall consists of a single layer of secretory cells, each with a large vacuole and a minute acidophilic granule towards the gland lumen (McQueen et al., 2022). It arises from the segment 9 (male genital) primordium in the female genital disc (McQueen et al., 2022).
has exact synonym: appendicular gland
has exact synonym: colleterial gland
has exact synonym: female AcGl
has exact synonym: parovarium
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004914
in subset: cur

Axiom
annotated source: female accessory gland
annotated property: definition
annotated target: Small, bilaterally paired gland that lies caudal to the spermathecae and is connected to the uterus by a duct (McQueen et al., 2022). The gland wall consists of a single layer of secretory cells, each with a large vacuole and a minute acidophilic granule towards the gland lumen (McQueen et al., 2022). It arises from the segment 9 (male genital) primordium in the female genital disc (McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0141451
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: female accessory gland
annotated property: hasExactSynonym
annotated target: appendicular gland
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: female accessory gland
annotated property: hasExactSynonym
annotated target: colleterial gland
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: female accessory gland
annotated property: hasExactSynonym
annotated target: female AcGl
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: female accessory gland
annotated property: hasExactSynonym
annotated target: parovarium
database_cross_reference: FlyBase:FBrf0031004
database_cross_reference: FlyBase:FBrf0253444

female accessory gland duct
type: Class
subclass of: FBbt_00007474
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: female accessory gland
subclass of: Restriction
  on property: continuous with
  some values from: female accessory gland
subclass of: Restriction
  on property: continuous with
  some values from: uterus
subclass of: Restriction
  on property: develops from
  some values from: male genital primordium (female)
definition: A duct connecting the female accessory gland to the uterus, opening just caudal to the spermathecal ducts (McQueen et al., 2022). It consists of a tube of thin epithelium lined with a thin chitinous intima, irregularly ringed with sharp ridges that project into the lumen (McQueen et al., 2022). It develops from the male genital primordium of the female genital disc (Keisman et al., 2001).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004915
in subset: cur

Axiom
annotated source: female accessory gland duct
annotated property: definition
annotated target: A duct connecting the female accessory gland to the uterus, opening just caudal to the spermathecal ducts (McQueen et al., 2022). It consists of a tube of thin epithelium lined with a thin chitinous intima, irregularly ringed with sharp ridges that project into the lumen (McQueen et al., 2022). It develops from the male genital primordium of the female genital disc (Keisman et al., 2001).
database_cross_reference: FlyBase:FBrf0141451
database_cross_reference: FlyBase:FBrf0186027
database_cross_reference: FlyBase:FBrf0253444

calyx of oviduct
type: Class
subclass of: FBbt_00007474
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: lateral oviduct
subclass of: Restriction
  on property: continuous with
  some values from: ovary
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052055
definition: The anterior-most, cup-shaped region of the lateral oviduct (Kapelnikov et al., 2008; McQueen et al., 2022). Formed by the joining together of the individual pedicels (small tubes coming from the base of each ovariole) (McQueen et al., 2022).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004918
in subset: cur

Axiom
annotated source: calyx of oviduct
annotated property: definition
annotated target: The anterior-most, cup-shaped region of the lateral oviduct (Kapelnikov et al., 2008; McQueen et al., 2022). Formed by the joining together of the individual pedicels (small tubes coming from the base of each ovariole) (McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0207258
database_cross_reference: FlyBase:FBrf0253444

uterus
type: Class
subclass of: FBbt_00048491
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: genital chamber
subclass of: Restriction
  on property: continuous with
  some values from: common oviduct
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110693
definition: Anterior part of the genital chamber (McQueen et al., 2022). It is an ectodermal invagination that is the site of egg fertilization (McQueen et al., 2022). It is connected to the common oviduct anterodorsally and the vagina posteriorly (McQueen et al., 2022). It is surrounded by muscles (McQueen et al., 2022).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004924
in subset: cur

Axiom
annotated source: uterus
annotated property: definition
annotated target: Anterior part of the genital chamber (McQueen et al., 2022). It is an ectodermal invagination that is the site of egg fertilization (McQueen et al., 2022). It is connected to the common oviduct anterodorsally and the vagina posteriorly (McQueen et al., 2022). It is surrounded by muscles (McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0253444

genital chamber
type: Class
subclass of: FBbt_00025993
subclass of: FBbt_00048491
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: adult
subclass of: Restriction
  on property: part of
  some values from: female reproductive system
subclass of: Restriction
  on property: develops from
  some values from: female genital disc
definition: An elongate muscular pouch, the anterior part of which is the uterus, where eggs are fertilized, and the posterior part of which is the vagina, where insemination takes place during copulation (McQueen et al., 2022). It opens posteriorly through the vulva (McQueen et al., 2022).
has alternative id: FBbt:00004919
has narrow synonym: uterus
has narrow synonym: vagina
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004925
in subset: cur

Axiom
annotated source: genital chamber
annotated property: definition
annotated target: An elongate muscular pouch, the anterior part of which is the uterus, where eggs are fertilized, and the posterior part of which is the vagina, where insemination takes place during copulation (McQueen et al., 2022). It opens posteriorly through the vulva (McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: genital chamber
annotated property: hasNarrowSynonym
annotated target: uterus
database_cross_reference: FlyBase:FBrf0253444

oviprovector
type: Class
subclass of: FBbt_00007288
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: adult abdominal segment 8
subclass of: Restriction
  on property: part of
  some values from: female genitalia
subclass of: Restriction
  on property: part of
  some values from: adult integumentary system
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110695
definition: Eversible membrane between the hypogynial valves that surrounds the vagina and the vulva (McQueen et al., 2022).
has exact synonym: dented membrane
has OBO namespace: fly_anatomy.ontology
has related synonym: vagina
has related synonym: vulva
id: FBbt:00004926
in subset: cur

Axiom
annotated source: oviprovector
annotated property: definition
annotated target: Eversible membrane between the hypogynial valves that surrounds the vagina and the vulva (McQueen et al., 2022).
database_cross_reference: FlyBase:FBrf0031004
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: oviprovector
annotated property: hasExactSynonym
annotated target: dented membrane
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: oviprovector
annotated property: hasRelatedSynonym
annotated target: vagina
database_cross_reference: FlyBase:FBrf0253444

Axiom
annotated source: oviprovector
annotated property: hasRelatedSynonym
annotated target: vulva
database_cross_reference: FlyBase:FBrf0091028
database_cross_reference: FlyBase:FBrf0098967
database_cross_reference: FlyBase:FBrf0253444

male reproductive system
type: Class
equivalent class: Class
  intersection of: reproductive system
  intersection of: Restriction
    on property: part of
    some values from: male organism
subclass of: reproductive system
subclass of: FBbt_00048490
definition: Any reproductive system (FBbt:00004857) that is part of some male organism (FBbt:00007004).
database_cross_reference: UBERON:0000079
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004927
in subset: FlyTed
in subset: cur

Axiom
annotated source: male reproductive system
annotated property: definition
annotated target: Any reproductive system (FBbt:00004857) that is part of some male organism (FBbt:00007004).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0034075

testis
type: Class
subclass of: gonad
subclass of: FBbt_00048490
subclass of: Restriction
  on property: part of
  some values from: adult
subclass of: Restriction
  on property: part of
  some values from: male reproductive system
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00058110
definition: Tube of the male reproductive system connected to the seminal vesicle at the basal end. It is a tube 1.9mm long and 90-100 micrometers in diameter, with the basal half helically coiled and the distal half forming a freely extended arc. The coiled portion is spirally wound twice around a center occupied by the testicular duct and the distal portion of the seminal vesicle. The wall of the testis consists of two very thin layers containing widely spaced nuclei: an inner sheath and an outer sheath composed of small flattened polygonal cells that contain yellow pigment granules. The development of germline cells takes place in the testis.
database_cross_reference: UBERON:0000473
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004928
in subset: FlyTed
in subset: cur

Axiom
annotated source: testis
annotated property: definition
annotated target: Tube of the male reproductive system connected to the seminal vesicle at the basal end. It is a tube 1.9mm long and 90-100 micrometers in diameter, with the basal half helically coiled and the distal half forming a freely extended arc. The coiled portion is spirally wound twice around a center occupied by the testicular duct and the distal portion of the seminal vesicle. The wall of the testis consists of two very thin layers containing widely spaced nuclei: an inner sheath and an outer sheath composed of small flattened polygonal cells that contain yellow pigment granules. The development of germline cells takes place in the testis.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0033532

cyst cell of testis
type: Class
subclass of: somatic cell of testis
subclass of: Restriction
  on property: part of
  some values from: male germline cyst
subclass of: Restriction
  on property: develops from
  some values from: cyst progenitor cell
definition: One of a pair of somatic cells that envelope each cyst of developing male germline cells.
has broad synonym: cyst cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004931
in subset: FlyTed
in subset: cur

Axiom
annotated source: cyst cell of testis
annotated property: definition
annotated target: One of a pair of somatic cells that envelope each cyst of developing male germline cells.
database_cross_reference: FlyBase:FBrf0064778

cyst progenitor cell
type: Class
subclass of: gonadal somatic stem cell
subclass of: somatic cell of testis
subclass of: Restriction
  on property: part of
  some values from: germinal proliferation center
definition: A somatic stem cell; Mother of cyst cells; Associated with the hub of the germinal center and with male germline stem cells.
has alternative id: FBbt:00004932
has exact synonym: CySC
has exact synonym: somatic cyst stem cell
has OBO namespace: fly_anatomy.ontology
has related synonym: cyst stem cell
id: FBbt:00004933
in subset: FlyTed
in subset: cur

Axiom
annotated source: cyst progenitor cell
annotated property: definition
annotated target: A somatic stem cell; Mother of cyst cells; Associated with the hub of the germinal center and with male germline stem cells.
database_cross_reference: FlyBase:FBrf0064778

Axiom
annotated source: cyst progenitor cell
annotated property: hasExactSynonym
annotated target: CySC
database_cross_reference: FlyBase:FBrf0219716

Axiom
annotated source: cyst progenitor cell
annotated property: hasExactSynonym
annotated target: somatic cyst stem cell
database_cross_reference: FlyBase:FBrf0219716

male accessory gland
type: Class
subclass of: FBbt_00048490
subclass of: FBbt_00100317
subclass of: Restriction
  on property: part of
  some values from: adult
subclass of: Restriction
  on property: part of
  some values from: male reproductive system
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110680
subclass of: Restriction
  on property: capable of
  some values from: GO_0007589
definition: Paired distended tubular accessory gland of the male genitalia which opens into the ejaculatory duct just behind the vas deferens. It is composed of binucleate cells.
has exact synonym: male AcGl
has exact synonym: paragonium
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004959
in subset: FlyTed
in subset: cur

Axiom
annotated source: male accessory gland
annotated property: definition
annotated target: Paired distended tubular accessory gland of the male genitalia which opens into the ejaculatory duct just behind the vas deferens. It is composed of binucleate cells.
database_cross_reference: FlyBase:FBrf0029539

Axiom
annotated source: male accessory gland
annotated property: hasExactSynonym
annotated target: male AcGl
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: male accessory gland
annotated property: hasExactSynonym
annotated target: paragonium
database_cross_reference: FlyBase:FBrf0007735

male accessory gland main cell
type: Class
subclass of: FBbt_00058232
definition: Cell type found in both lobes of the male accessory gland. These cells are flat, hexagonal and binucleate, which secrete their products into the lumen of each lobe. There are approximately 1000 main cells per lobe, interspersed with around 43 secondary cells.
has exact synonym: main secretory cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004960
in subset: FlyTed
in subset: cur

Axiom
annotated source: male accessory gland main cell
annotated property: definition
annotated target: Cell type found in both lobes of the male accessory gland. These cells are flat, hexagonal and binucleate, which secrete their products into the lumen of each lobe. There are approximately 1000 main cells per lobe, interspersed with around 43 secondary cells.
database_cross_reference: FlyBase:FBrf0057142

Axiom
annotated source: male accessory gland main cell
annotated property: hasExactSynonym
annotated target: main secretory cell
database_cross_reference: FlyBase:FBrf0152376

ejaculatory bulb
type: Class
subclass of: FBbt_00048490
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: ejaculatory duct
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110685
definition: Bilaterally symmetric structure with two anterior and two posterior lateral lobes, a sclerotized rod-like apodeme arising from its upper side and muscles fibers radiating from the end of the rod to the side walls. The anterior ejaculatory duct enters the bulb on the upper side and the posterior ejaculatory duct arises between the paired projections on the opposite side. The walls of the bulb consists of a thick columnar epithelium lined with a well developed intima, enclosing a chamber filled with clear viscous fluid.
has exact synonym: sperm pump
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004962
in subset: FlyTed
in subset: cur

Axiom
annotated source: ejaculatory bulb
annotated property: definition
annotated target: Bilaterally symmetric structure with two anterior and two posterior lateral lobes, a sclerotized rod-like apodeme arising from its upper side and muscles fibers radiating from the end of the rod to the side walls. The anterior ejaculatory duct enters the bulb on the upper side and the posterior ejaculatory duct arises between the paired projections on the opposite side. The walls of the bulb consists of a thick columnar epithelium lined with a well developed intima, enclosing a chamber filled with clear viscous fluid.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0029539
database_cross_reference: FlyBase:FBrf0075527

ejaculatory duct
type: Class
subclass of: FBbt_00048490
subclass of: FBbt_00100314
subclass of: Restriction
  on property: part of
  some values from: adult
subclass of: Restriction
  on property: part of
  some values from: male reproductive system
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110684
definition: Unpaired duct that connects the male accessory glands and vasa deferentia to the aedeagus in the adult male genitalia. It is divided in an anterior ejaculatory duct and a posterior ejaculatory duct, separated by the ejaculatory bulb (Miller, 1941).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004965
in subset: FlyTed
in subset: cur

Axiom
annotated source: ejaculatory duct
annotated property: definition
annotated target: Unpaired duct that connects the male accessory glands and vasa deferentia to the aedeagus in the adult male genitalia. It is divided in an anterior ejaculatory duct and a posterior ejaculatory duct, separated by the ejaculatory bulb (Miller, 1941).
database_cross_reference: FlyBase:FBrf0005539
database_cross_reference: FlyBase:FBrf0075527

integumentary system
type: Class
subclass of: organ system
definition: The organ system that forms the covering layer of the animal.
database_cross_reference: UBERON:0002416
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004969
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: integumentary system
annotated property: definition
annotated target: The organ system that forms the covering layer of the animal.
database_cross_reference: FBC:GG

cuticle
type: Class
subclass of: acellular anatomical structure
subclass of: Restriction
  on property: part of
  some values from: integumentary system
subclass of: Restriction
  on property: develops from
  some values from: epidermis
definition: The outer non-living layer of the integumentary system that is secreted by the underlying epidermis.
database_cross_reference: UBERON:0001001
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004970
in subset: FB gloss
in subset: cur

Axiom
annotated source: cuticle
annotated property: definition
annotated target: The outer non-living layer of the integumentary system that is secreted by the underlying epidermis.
database_cross_reference: FlyBase:FBrf0064790

trichome
type: Class
subclass of: FBbt_00007245
definition: Non-innervated projection of the cuticle around an actin-rich cellular process of an underlying epidermal cell.
database_cross_reference: UBERON:6004979
has OBO namespace: fly_anatomy.ontology
has related synonym: cell hair
id: FBbt:00004979
in subset: cur

Axiom
annotated source: trichome
annotated property: definition
annotated target: Non-innervated projection of the cuticle around an actin-rich cellular process of an underlying epidermal cell.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval cuticle
type: Class
subclass of: cuticle
subclass of: Restriction
  on property: part of
  some values from: larval integumentary system
definition: Cuticle of the late embryo or larva.
database_cross_reference: UBERON:6004983
has exact synonym: larval cuticle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004983
in subset: cur

Axiom
annotated source: embryonic/larval cuticle
annotated property: definition
annotated target: Cuticle of the late embryo or larva.
database_cross_reference: FlyBase:FBrf0234504

epidermis
type: Class
subclass of: cuboidal/columnar epithelium
subclass of: Restriction
  on property: part of
  some values from: integumentary system
definition: Tissue composed of epithelial cells. It secretes and underlies the cuticle.
database_cross_reference: UBERON:0007376
has OBO namespace: fly_anatomy.ontology
has related synonym: hypoderm
has related synonym: hypodermis
id: FBbt:00004993
in subset: FB gloss
in subset: cur

Axiom
annotated source: epidermis
annotated property: definition
annotated target: Tissue composed of epithelial cells. It secretes and underlies the cuticle.
database_cross_reference: FlyBase:FBrf0064790

oenocyte
type: Class
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: epidermis
definition: Large cell located in a cluster or row under the abdominal epidermis, to which it is as attached.
database_cross_reference: CL:0000487
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004995
in subset: FB gloss
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: oenocyte
annotated property: definition
annotated target: Large cell located in a cluster or row under the abdominal epidermis, to which it is as attached.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

tracheal system
type: Class
subclass of: BFO_0000040
subclass of: organ system
subclass of: Restriction
  on property: capable of
  some values from: GO_0007585
definition: Air-filled network of tracheae, opening to the exterior via spiracles and containing minute tracheoles where gaseous exchange between air and tissues occurs (Miller, 1950).
database_cross_reference: UBERON:0005155
has exact synonym: respiratory system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005024
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: tracheal system
annotated property: definition
annotated target: Air-filled network of tracheae, opening to the exterior via spiracles and containing minute tracheoles where gaseous exchange between air and tissues occurs (Miller, 1950).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0064787

Axiom
annotated source: tracheal system
annotated property: hasExactSynonym
annotated target: respiratory system
database_cross_reference: FlyBase:FBrf0007735

tracheocyte
type: Class
subclass of: epithelial cell
subclass of: Restriction
  on property: part of
  some values from: tracheal system
definition: Epithelial cell of the tracheal epithelium.
database_cross_reference: CL:0008026
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005038
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: tracheocyte
annotated property: definition
annotated target: Epithelial cell of the tracheal epithelium.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

larval tracheocyte
type: Class
equivalent class: Class
  intersection of: tracheocyte
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: tracheocyte
subclass of: FBbt_00058239
subclass of: Restriction
  on property: part of
  some values from: larval tracheal system
definition: Any tracheocyte of the larva.
has exact synonym: embryonic/larval tracheocyte
has OBO namespace: fly_anatomy.ontology
has related synonym: larval tracheal cell
id: FBbt:00005039

Axiom
annotated source: larval tracheocyte
annotated property: definition
annotated target: Any tracheocyte of the larva.
database_cross_reference: FBC:Autogenerated

adult tracheocyte
type: Class
equivalent class: Class
  intersection of: tracheocyte
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: tracheocyte
subclass of: FBbt_00058238
subclass of: Restriction
  on property: part of
  some values from: adult tracheal system
definition: Any tracheocyte of the adult.
has OBO namespace: fly_anatomy.ontology
has related synonym: adult tracheal cell
id: FBbt:00005040
in subset: cur

Axiom
annotated source: adult tracheocyte
annotated property: definition
annotated target: Any tracheocyte of the adult.
database_cross_reference: FBC:Autogenerated

digestive system
type: Class
subclass of: organ system
definition: Organ system comprising the alimentary canal and its associated organs, including the mouthparts, labellar and salivary glands and the Malpighian tubules (Miller, 1950).
database_cross_reference: UBERON:0001007
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005055
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: digestive system
annotated property: definition
annotated target: Organ system comprising the alimentary canal and its associated organs, including the mouthparts, labellar and salivary glands and the Malpighian tubules (Miller, 1950).
database_cross_reference: FlyBase:FBrf0007735

excretory system
type: Class
subclass of: organ system
definition: The system of organs and cells involved in the excretion of waste products.
database_cross_reference: UBERON:0001008
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005056
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: excretory system
annotated property: definition
annotated target: The system of organs and cells involved in the excretion of waste products.
database_cross_reference: FlyBase:FBrf0064792

circulatory system
type: Class
subclass of: organ system
definition: System that functions to circulate hemolymph throughout the body. It is an open circulatory system, consisting of the dorsal vessel, body cavity, accessory pulsatile organs and the hemolymph (Miller, 1950).
database_cross_reference: UBERON:0009054
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005057
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: circulatory system
annotated property: definition
annotated target: System that functions to circulate hemolymph throughout the body. It is an open circulatory system, consisting of the dorsal vessel, body cavity, accessory pulsatile organs and the hemolymph (Miller, 1950).
database_cross_reference: FlyBase:FBrf0007735

hemocyte
type: Class
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: circulatory system
subclass of: Restriction
  on property: expresses
  some values from: FBgn0028430
definition: Blood cell of the circulatory system that is involved in the cellular immune response. It expresses Hemese, a pan-hemocyte marker (Tattikota et al., 2020).
database_cross_reference: CL:0000387
has exact synonym: haemocyte
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005063
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: hemocyte
annotated property: definition
annotated target: Blood cell of the circulatory system that is involved in the cellular immune response. It expresses Hemese, a pan-hemocyte marker (Tattikota et al., 2020).
database_cross_reference: FlyBase:FBrf0200434
database_cross_reference: FlyBase:FBrf0245741

adipose system
type: Class
subclass of: organ system
definition: The system of organs and cells involved in fat storage.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005065
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: adipose system
annotated property: definition
annotated target: The system of organs and cells involved in fat storage.
database_cross_reference: FBC:GG

fat body
type: Class
subclass of: BFO_0000040
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: adipose system
subclass of: Restriction
  on property: capable of
  some values from: GO_0019915
subclass of: Restriction
  on property: composed primarily of
  some values from: FBbt_00046052
definition: Collective term for the masses and sheets of adipose tissue that are distributed throughout the organism's body. The adult and larval fat bodies are composed of different cell lineages, but perform the same main function of fat storage (Musselman and Kuhnlein, 2018).
database_cross_reference: UBERON:0003917
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005066
in subset: FB gloss
in subset: cur

Axiom
annotated source: fat body
annotated property: definition
annotated target: Collective term for the masses and sheets of adipose tissue that are distributed throughout the organism's body. The adult and larval fat bodies are composed of different cell lineages, but perform the same main function of fat storage (Musselman and Kuhnlein, 2018).
database_cross_reference: FlyBase:FBrf0031020
database_cross_reference: FlyBase:FBrf0064793
database_cross_reference: FlyBase:FBrf0238315

fat body primordium
type: Class
subclass of: primordium
subclass of: somatic trunk mesoderm derivative
subclass of: Restriction
  on property: develops from
  some values from: fat body/gonad primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic/larval fat body
definition: The fat body primordium after the gonadal sheath primordium splits from it during stage 14. By stage 15, the different primordia fuse to form a continuous layer (Hoshizaki et al., 1994). The precursor fat cells it contains continue differentiating until stage 17, when the primordium becomes the fat body proper (Campos-Ortega and Hartenstein, 1997).
has narrow synonym: embryonic fat body
has OBO namespace: fly_anatomy.ontology
has related synonym: fat body specific anlage
id: FBbt:00005067
in subset: cur

Axiom
annotated source: fat body primordium
annotated property: definition
annotated target: The fat body primordium after the gonadal sheath primordium splits from it during stage 14. By stage 15, the different primordia fuse to form a continuous layer (Hoshizaki et al., 1994). The precursor fat cells it contains continue differentiating until stage 17, when the primordium becomes the fat body proper (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0073371
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: fat body primordium
annotated property: hasNarrowSynonym
annotated target: embryonic fat body
database_cross_reference: FBC:DPG

endocrine system
type: Class
subclass of: FBbt_00007278
definition: Non-connected system of anatomical structures which have some endocrine function.
database_cross_reference: UBERON:0000949
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005068
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: endocrine system
annotated property: definition
annotated target: Non-connected system of anatomical structures which have some endocrine function.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

muscle system
type: Class
subclass of: organ system
definition: System of contractile somatic and visceral muscle fibers arranged in groups and layers (Miller, 1950).
has exact synonym: muscular system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005069
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: muscle system
annotated property: definition
annotated target: System of contractile somatic and visceral muscle fibers arranged in groups and layers (Miller, 1950).
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0031016
database_cross_reference: FlyBase:FBrf0041814
database_cross_reference: FlyBase:FBrf0044229
database_cross_reference: FlyBase:FBrf0064793

Axiom
annotated source: muscle system
annotated property: hasExactSynonym
annotated target: muscular system
database_cross_reference: FlyBase:FBrf0007735

visceral muscle cell
type: Class
subclass of: muscle cell
definition: Muscle cell of a muscle that moves the viscera, usually with a peristaltic or compressing function, and has only one or, commonly no attachment to the body wall. Visceral muscles differ from somatic muscles in several respects: adjacent fibers are held together by desmosomes, each fiber is uninucleate and the contractile material is not grouped into fibrils but packs the whole fiber. The visceral musculature comprises musculature of the intestine, reproductive system and circulatory system (Miller, 1950). The circular fibers derive from a bilaterally symmetrical band of mesodermal cells extending continuously throughout most of the germ band. The longitudinal fibers derive from clusters of mesodermal cells which appear during stage 12 at the posterior end of the embryo and migrate anteriorly.
has broad synonym: smooth muscle
database_cross_reference: CL:0008007
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005070
in subset: cur
comment: It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however most visceral (and somatic) muscles in Drosophila are actually striated (Miller, 1950; Bate, 1993).

Axiom
annotated source: visceral muscle cell
annotated property: definition
annotated target: Muscle cell of a muscle that moves the viscera, usually with a peristaltic or compressing function, and has only one or, commonly no attachment to the body wall. Visceral muscles differ from somatic muscles in several respects: adjacent fibers are held together by desmosomes, each fiber is uninucleate and the contractile material is not grouped into fibrils but packs the whole fiber. The visceral musculature comprises musculature of the intestine, reproductive system and circulatory system (Miller, 1950). The circular fibers derive from a bilaterally symmetrical band of mesodermal cells extending continuously throughout most of the germ band. The longitudinal fibers derive from clusters of mesodermal cells which appear during stage 12 at the posterior end of the embryo and migrate anteriorly.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0064793
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0239227

somatic muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00058111
subclass of: muscle cell
subclass of: FBbt_00007290
subclass of: Restriction
  on property: part of
  some values from: FBbt_00058111
definition: Muscle cell that serves to change the position of some part of the body. These cells are usually attached to the body wall. Fibers of somatic muscles are multinucleate, with the contractile material grouped into fibrils.
database_cross_reference: CL:0008004
has exact synonym: Somatic and visceral muscles appear striated (Miller, 1950).
has exact synonym: skeletal muscle cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005073
in subset: cur

Axiom
annotated source: somatic muscle cell
annotated property: definition
annotated target: Muscle cell that serves to change the position of some part of the body. These cells are usually attached to the body wall. Fibers of somatic muscles are multinucleate, with the contractile material grouped into fibrils.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0239227
database_cross_reference: FlyBase:FBrf0239342

muscle cell
type: Class
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: muscle system
definition: Somatic, contractile cell that makes up a muscle. It is formed by several fusion events between fusion competent myoblasts and one founder cell.
database_cross_reference: CL:0000187
has OBO namespace: fly_anatomy.ontology
has related synonym: muscle fiber
has related synonym: myofiber
has related synonym: myofibril
id: FBbt:00005074
in subset: cur
in subset: scrnaseq slim
comment: In contrast to vertebrates, in Drosophila embryos and larva, each muscle is a single myotube (Maqbool and Jagla, 2007).

Axiom
annotated source: muscle cell
annotated property: definition
annotated target: Somatic, contractile cell that makes up a muscle. It is formed by several fusion events between fusion competent myoblasts and one founder cell.
database_cross_reference: FlyBase:FBrf0051585
database_cross_reference: FlyBase:FBrf0205186
database_cross_reference: FlyBase:FBrf0217289

Axiom
annotated source: muscle cell
annotated property: hasRelatedSynonym
annotated target: muscle fiber
database_cross_reference: FlyBase:FBrf0217289

Axiom
annotated source: muscle cell
annotated property: hasRelatedSynonym
annotated target: myofiber
database_cross_reference: FlyBase:FBrf0217289

Axiom
annotated source: muscle cell
annotated property: hasRelatedSynonym
annotated target: myofibril
database_cross_reference: FlyBase:FBrf0212347

myoblast
type: Class
subclass of: somatic precursor cell
definition: Muscle progenitor cell.
database_cross_reference: CL:0000056
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005083
in subset: cur

Axiom
annotated source: myoblast
annotated property: definition
annotated target: Muscle progenitor cell.
database_cross_reference: FlyBase:FBrf0217289

apodeme
type: Class
subclass of: FBbt_00007288
definition: A cuticular ingrowth of the exoskeleton, sometimes only a peg, frequently ridge-like, and often serving as a muscle attachment site. Does not generally correspond to superficial invaginations.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005091
in subset: FB gloss
in subset: cur

Axiom
annotated source: apodeme
annotated property: definition
annotated target: A cuticular ingrowth of the exoskeleton, sometimes only a peg, frequently ridge-like, and often serving as a muscle attachment site. Does not generally correspond to superficial invaginations.
database_cross_reference: FlyBase:FBrf0111704
database_cross_reference: FlyBase:FBrf0166419
database_cross_reference: FlyBase:FBrf0230923

nervous system
type: Class
subclass of: organ system
definition: All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.
database_cross_reference: UBERON:0001016
database_cross_reference: VFB:FBbt_00005093
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005093
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: nervous system
annotated property: definition
annotated target: All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.
database_cross_reference: FlyBase:FBrf0166419

central nervous system
type: Class
subclass of: FBbt_00007330
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: Collective name for all the nerve centers and their connective in the insect's body. In the context of Drosophila refers to the part of the nervous system consisting of the brain and ventral ganglia.
database_cross_reference: UBERON:0001017
database_cross_reference: VFB:FBbt_00005094
has OBO namespace: fly_anatomy.ontology
has related synonym: CNS
id: FBbt:00005094
in subset: FB gloss
in subset: cur

Axiom
annotated source: central nervous system
annotated property: definition
annotated target: Collective name for all the nerve centers and their connective in the insect's body. In the context of Drosophila refers to the part of the nervous system consisting of the brain and ventral ganglia.
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0166419

brain
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Anterodorsal portion of the central nervous system. The neuromeres considered to be part of the brain vary by stage. In the larva, the cerebral (supraesophageal) neuromeres, which form a bilateral pair of lobes, constitute the brain (Urbach and Technau, 2003; Li et al., 2014; Crews, 2019). During metamorphosis, the gnathal ganglion separates from the prothoracic neuromere and fuses with the supraesophageal ganglion, to become the ventral part of the adult brain (Ito et al., 2014; Hartenstein et al., 2018; Kendroud et al., 2018).
database_cross_reference: UBERON:0000955
database_cross_reference: VFB:FBbt_00005095
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005095
in subset: FB gloss
in subset: cur

Axiom
annotated source: brain
annotated property: definition
annotated target: Anterodorsal portion of the central nervous system. The neuromeres considered to be part of the brain vary by stage. In the larva, the cerebral (supraesophageal) neuromeres, which form a bilateral pair of lobes, constitute the brain (Urbach and Technau, 2003; Li et al., 2014; Crews, 2019). During metamorphosis, the gnathal ganglion separates from the prothoracic neuromere and fuses with the supraesophageal ganglion, to become the ventral part of the adult brain (Ito et al., 2014; Hartenstein et al., 2018; Kendroud et al., 2018).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0225812
database_cross_reference: FlyBase:FBrf0237251
database_cross_reference: FlyBase:FBrf0237252
database_cross_reference: FlyBase:FBrf0244240

ventral nerve cord
type: Class
subclass of: FBbt_00007330
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Posterior region of the central nervous system containing the thoracic and abdominal neuromeres (Clark et al., 2018; Court et al., 2020). In the larva it is joined at its anterior end to the posterior gnathal ganglion (Eschbach and Zlatic, 2020). In the adult it is a separate entity, connected to the brain by the neck connective (Ito et al., 2014; Court et al., 2020).
database_cross_reference: UBERON:0000934
database_cross_reference: VFB:FBbt_00005097
has exact synonym: ventral nervous system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005097
in subset: cur

Axiom
annotated source: ventral nerve cord
annotated property: definition
annotated target: Posterior region of the central nervous system containing the thoracic and abdominal neuromeres (Clark et al., 2018; Court et al., 2020). In the larva it is joined at its anterior end to the posterior gnathal ganglion (Eschbach and Zlatic, 2020). In the adult it is a separate entity, connected to the brain by the neck connective (Ito et al., 2014; Court et al., 2020).
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0238752
database_cross_reference: FlyBase:FBrf0246815
database_cross_reference: FlyBase:FBrf0247585

peripheral nervous system
type: Class
subclass of: FBbt_00007330
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: The outer parts of the nervous system that perform sensory and motor functions.
database_cross_reference: UBERON:0000010
database_cross_reference: VFB:FBbt_00005098
has OBO namespace: fly_anatomy.ontology
has related synonym: PNS
id: FBbt:00005098
in subset: FB gloss
in subset: cur

Axiom
annotated source: peripheral nervous system
annotated property: definition
annotated target: The outer parts of the nervous system that perform sensory and motor functions.
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0064796

neuron projection bundle
type: Class
equivalent class: Class
  intersection of: CARO_0001001
  intersection of: Restriction
    on property: part of
    some values from: NCBITaxon 7227
subclass of: CARO_0001001
subclass of: multi-cell-component structure
subclass of: Restriction
  on property: part of
  some values from: nervous system
subclass of: Restriction
  on property: characteristic of
  some values from: PATO_0001861
definition: A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses.
database_cross_reference: CARO:0001001
database_cross_reference: UBERON:0000122
database_cross_reference: VFB:FBbt_00005099
has exact synonym: nerve fiber bundle
has OBO namespace: fly_anatomy.ontology
has related synonym: nerve fiber
id: FBbt:00005099
in subset: cur
in subset: larval OF

Axiom
annotated source: neuron projection bundle
annotated property: definition
annotated target: A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: neuron projection bundle
annotated property: hasExactSynonym
annotated target: nerve fiber bundle
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: neuron projection bundle
annotated property: hasRelatedSynonym
annotated target: nerve fiber
database_cross_reference: https://orcid.org/0000-0002-7073-9172

tract
type: Class
subclass of: neuron projection bundle
subclass of: Restriction
  on property: part of
  some values from: FBbt_00040004
definition: A neuron projection bundle linking two or more synaptic neuropil domains or subdomains within the CNS.
database_cross_reference: UBERON:0001018
database_cross_reference: VFB:FBbt_00005100
has exact synonym: CNS tract
has narrow synonym: axon tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005100
in subset: cur
in subset: larval OF

Axiom
annotated source: tract
annotated property: definition
annotated target: A neuron projection bundle linking two or more synaptic neuropil domains or subdomains within the CNS.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

symmetrical commissure
type: Class
subclass of: commissure
definition: A symmetrical CNS tract that crosses the midline.
has broad synonym: commissure
database_cross_reference: VFB:FBbt_00005103
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005103
in subset: FB gloss
in subset: cur

Axiom
annotated source: symmetrical commissure
annotated property: definition
annotated target: A symmetrical CNS tract that crosses the midline.
database_cross_reference: FlyBase:FBrf0166419

Axiom
annotated source: symmetrical commissure
annotated property: hasBroadSynonym
annotated target: commissure
database_cross_reference: FlyBase:FBrf0166419

connective
type: Class
subclass of: FBbt_00007426
definition: A longitudinally oriented fascicle that connects two or more neuromeres.
database_cross_reference: VFB:FBbt_00005104
has exact synonym: longitudinal axon tract
has exact synonym: longitudinal fascicle
has exact synonym: longitudinal fiber
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005104
in subset: FB gloss
in subset: cur

Axiom
annotated source: connective
annotated property: definition
annotated target: A longitudinally oriented fascicle that connects two or more neuromeres.
database_cross_reference: FlyBase:FBrf0166419
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: connective
annotated property: hasExactSynonym
annotated target: longitudinal axon tract
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: connective
annotated property: hasExactSynonym
annotated target: longitudinal fiber
database_cross_reference: FlyBase:FBrf0237252

nerve
type: Class
equivalent class: Class
  intersection of: neuron projection bundle
  intersection of: Restriction
    on property: part of
    some values from: peripheral nervous system
subclass of: neuron projection bundle
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
definition: A bundle of axons connecting the peripheral nervous system to the central nervous system.
database_cross_reference: UBERON:0001021
database_cross_reference: VFB:FBbt_00005105
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005105
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: nerve
annotated property: definition
annotated target: A bundle of axons connecting the peripheral nervous system to the central nervous system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

neuron
type: Class
equivalent class: Class
  intersection of: CL_0000540
  intersection of: Restriction
    on property: part of
    some values from: NCBITaxon 7227
subclass of: CL_0000540
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: Electrically active cell of the nervous system which has an axon and/or dendrite and which is synapsed with other cells and/or has other cells synapsed to it.
database_cross_reference: CL:0000540
database_cross_reference: VFB:FBbt_00005106
has OBO namespace: fly_anatomy.ontology
has related synonym: nerve cell
id: FBbt:00005106
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
in subset: larval OF
in subset: scrnaseq slim

Axiom
annotated source: neuron
annotated property: definition
annotated target: Electrically active cell of the nervous system which has an axon and/or dendrite and which is synapsed with other cells and/or has other cells synapsed to it.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

motor neuron
type: Class
subclass of: FBbt_00051963
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: muscle cell
definition: A neuron that sends movement impulses to the muscle system.
database_cross_reference: CL:0000100
database_cross_reference: VFB:FBbt_00005123
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005123
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: motor neuron
annotated property: definition
annotated target: A neuron that sends movement impulses to the muscle system.
database_cross_reference: FBC:GG

sensory neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: CL_0000101
subclass of: FBbt_00007693
definition: Any neuron (FBbt:00005106) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
database_cross_reference: CL:0000101
database_cross_reference: VFB:FBbt_00005124
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005124
in subset: cur
in subset: larval OF
in subset: scrnaseq slim

Axiom
annotated source: sensory neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
database_cross_reference: FBC:Autogenerated

interneuron
type: Class
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: A neuron that is entirely confined to the central nervous system and is neither a sensory neuron nor a motor neuron.
has alternative id: FBbt:00005126
database_cross_reference: CL:0000099
database_cross_reference: VFB:FBbt_00005125
has exact synonym: central neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005125
in subset: FB gloss
in subset: cur
in subset: larval OF
in subset: scrnaseq slim
comment: alt_id of FBbt:00005126 moved over following obsoletion of 'intrinsic neuron', unclear what this term was or whether 'interneuron' is a suitable replacement.

Axiom
annotated source: interneuron
annotated property: definition
annotated target: A neuron that is entirely confined to the central nervous system and is neither a sensory neuron nor a motor neuron.
database_cross_reference: FlyBase:FBrf0216671
database_cross_reference: FlyBase:FBrf0247998

Axiom
annotated source: interneuron
annotated property: hasExactSynonym
annotated target: central neuron
database_cross_reference: FlyBase:FBrf0247998

optic lobe amacrine neuron
type: Class
subclass of: FBbt_00007577
definition: Optic lobe intrinsic neuron without defined axons or dendrites, having processes with mixed pre- and post-synapses in approximately the same ratio throughout the cell (Matsliah et al., 2024). Some amacrine cells, such as CT1, have multiple compartmentalized, modular arborizations (Meier and Borst, 2019).
has broad synonym: amacrine cell
database_cross_reference: VFB:FBbt_00005127
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005127
in subset: cur

Axiom
annotated source: optic lobe amacrine neuron
annotated property: definition
annotated target: Optic lobe intrinsic neuron without defined axons or dendrites, having processes with mixed pre- and post-synapses in approximately the same ratio throughout the cell (Matsliah et al., 2024). Some amacrine cells, such as CT1, have multiple compartmentalized, modular arborizations (Meier and Borst, 2019).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0242197
database_cross_reference: FlyBase:FBrf0260545

adult optic lobe columnar neuron
type: Class
subclass of: FBbt_00052046
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: adult optic lobe
definition: Interneuron of the optic lobe whose primary projection extends along the long axis of a single optic column to which it, but not necessarily its collaterals, is restricted.
database_cross_reference: VFB:FBbt_00005129
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005129
in subset: cur
comment: This definition follows Fischbach and Dittrich (1989) in classifying based on the primary projection. A neuron with broad and extensive collaterals with terminals in adjacent columns is still classified as a columnar neuron under this definition. Other treatments have classified such neurons as tangential.

Axiom
annotated source: adult optic lobe columnar neuron
annotated property: definition
annotated target: Interneuron of the optic lobe whose primary projection extends along the long axis of a single optic column to which it, but not necessarily its collaterals, is restricted.
database_cross_reference: FlyBase:FBrf0049410

neurosecretory neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0046879
subclass of: CL_0000165
subclass of: neuron
definition: Any neuron (FBbt:00005106) that is capable of some hormone secretion (GO:0046879).
database_cross_reference: CL:0000165
database_cross_reference: VFB:FBbt_00005130
has exact synonym: NSN
has exact synonym: neurosecretory cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005130
in subset: cur

Axiom
annotated source: neurosecretory neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some hormone secretion (GO:0046879).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: neurosecretory neuron
annotated property: hasExactSynonym
annotated target: NSN
database_cross_reference: FlyBase:FBrf0134726

dopaminergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0061527
subclass of: CL_0000700
subclass of: FBbt_00007368
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00053522
definition: Any neuron (FBbt:00005106) that is capable of some dopamine secretion, neurotransmission (GO:0061527).
database_cross_reference: CL:0000700
database_cross_reference: VFB:FBbt_00005131
has exact synonym: DA neuron
has exact synonym: dopamine neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005131
in subset: cur

Axiom
annotated source: dopaminergic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some dopamine secretion, neurotransmission (GO:0061527).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: dopaminergic neuron
annotated property: hasExactSynonym
annotated target: DA neuron
database_cross_reference: FlyBase:FBrf0208427

ganglion
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: Any of a number of aggregations of neurons, glial cells and their processes, and surrounded by a glial cell and connective tissue sheath (plural: ganglia).
database_cross_reference: VFB:FBbt_00005137
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005137
in subset: FB gloss
in subset: cur
in subset: larval OF

neuropil
type: Class
subclass of: multi-cell-component structure
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Multi-cell component structure of the central nervous system consisting largely of neuron projections (tracts and synaptic neuropil domains) and associated glial cells. This corresponds to the part of the CNS that is enclosed by the cortex.
has alternative id: FBbt:00007351
database_cross_reference: UBERON:0002606
database_cross_reference: VFB:FBbt_00005139
has OBO namespace: fly_anatomy.ontology
has related synonym: neuropil
id: FBbt:00005139

Axiom
annotated source: neuropil
annotated property: definition
annotated target: Multi-cell component structure of the central nervous system consisting largely of neuron projections (tracts and synaptic neuropil domains) and associated glial cells. This corresponds to the part of the CNS that is enclosed by the cortex.
database_cross_reference: FlyBase:FBrf0224194

neuromere
type: Class
subclass of: FBbt_00007331
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: A segmental subdivision of the nervous system.
database_cross_reference: VFB:FBbt_00005140
has OBO namespace: fly_anatomy.ontology
has related synonym: ganglion
id: FBbt:00005140
in subset: FB gloss
in subset: cur

Axiom
annotated source: neuromere
annotated property: definition
annotated target: A segmental subdivision of the nervous system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

glial cell
type: Class
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: nervous system
subclass of: Restriction
  on property: develops from
  some values from: glioblast
definition: A supporting cell of the nervous system.
database_cross_reference: CL:0000125
database_cross_reference: VFB:FBbt_00005144
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005144
in subset: FB gloss
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: glial cell
annotated property: definition
annotated target: A supporting cell of the nervous system.
database_cross_reference: FBC:GG

glioblast
type: Class
subclass of: neuroblast
definition: Progenitor cell that gives rise only to glial cells and not neurons (Hartenstein, 2011).
database_cross_reference: CL:0000340
database_cross_reference: VFB:FBbt_00005145
has exact synonym: glial precursor cell
has OBO namespace: fly_anatomy.ontology
has related synonym: GP
id: FBbt:00005145
in subset: cur

Axiom
annotated source: glioblast
annotated property: definition
annotated target: Progenitor cell that gives rise only to glial cells and not neurons (Hartenstein, 2011).
database_cross_reference: FlyBase:FBrf0064795
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: glioblast
annotated property: hasRelatedSynonym
annotated target: GP
database_cross_reference: FlyBase:FBrf0055900

neuroblast
type: Class
subclass of: FBbt_00007344
IAO_0000028: NB
definition: Precursor of the central nervous system that derives from the neurogenic region of the ectoderm or the mesectoderm (Doe, 1992; Schmid et al., 1999; Crews, 2019). It produces neurons and/or glia (Doe, 1992; Beckervordersandforth et al., 2008). Neuroblasts may also divide during adult life to regenerate the adult brain (Fernandez-Hernandez et al., 2013).
database_cross_reference: CL:0000338
database_cross_reference: VFB:FBbt_00005146
has exact synonym: NB
has exact synonym: neural stem cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005146
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
comment: Adult neurogenesis demonstrated in the adult optic lobe in response to injury (Fernandez-Hernandez et al., 2013).

Axiom
annotated source: neuroblast
annotated property: definition
annotated target: Precursor of the central nervous system that derives from the neurogenic region of the ectoderm or the mesectoderm (Doe, 1992; Schmid et al., 1999; Crews, 2019). It produces neurons and/or glia (Doe, 1992; Beckervordersandforth et al., 2008). Neuroblasts may also divide during adult life to regenerate the adult brain (Fernandez-Hernandez et al., 2013).
database_cross_reference: FlyBase:FBrf0055900
database_cross_reference: FlyBase:FBrf0112030
database_cross_reference: FlyBase:FBrf0205499
database_cross_reference: FlyBase:FBrf0222020
database_cross_reference: FlyBase:FBrf0244240

Axiom
annotated source: neuroblast
annotated property: hasExactSynonym
annotated target: NB
has synonym type: VFB SYMBOL

Axiom
annotated source: neuroblast
annotated property: hasExactSynonym
annotated target: neural stem cell
database_cross_reference: FlyBase:FBrf0211926

neuroglioblast
type: Class
subclass of: neuroblast
definition: Precursor cell that gives rise to both neurons and glia (Hartenstein, 2011).
database_cross_reference: CL:0000468
database_cross_reference: VFB:FBbt_00005147
has exact synonym: NGB
has exact synonym: neuro-glioblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005147
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: neuroglioblast
annotated property: definition
annotated target: Precursor cell that gives rise to both neurons and glia (Hartenstein, 2011).
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: neuroglioblast
annotated property: hasExactSynonym
annotated target: NGB
database_cross_reference: FlyBase:FBrf0135724

Axiom
annotated source: neuroglioblast
annotated property: hasExactSynonym
annotated target: neuro-glioblast
database_cross_reference: FlyBase:FBrf0214261

surface glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: perineurium
subclass of: glial cell
subclass of: Restriction
  on property: part of
  some values from: perineurium
definition: Any glial cell that is part of (either layer of) the perineurium, which surrounds the entire nervous system (Kremer et al., 2017).
database_cross_reference: VFB:FBbt_00005152
has exact synonym: glial cell of the perineurium
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005152
in subset: cur

Axiom
annotated source: surface glial cell
annotated property: definition
annotated target: Any glial cell that is part of (either layer of) the perineurium, which surrounds the entire nervous system (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

perineurial glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: perineurial glial sheath
subclass of: surface glial cell
subclass of: Restriction
  on property: part of
  some values from: perineurial glial sheath
definition: Glial cell that forms part of the perineurial sheath forming the outer layer of the nervous system. These cells divide extensively to increase in number as the nervous system expands during development (Kremer et al., 2017).
database_cross_reference: VFB:FBbt_00005153
has exact synonym: PNG
has exact synonym: outer perineural sheath cell
has exact synonym: perineurial sheath cell
has exact synonym: perineurial sheath glial cell
has OBO namespace: fly_anatomy.ontology
has related synonym: apical glial cell
has related synonym: perineural cell
has related synonym: perineurial glia
id: FBbt:00005153
in subset: cur

Axiom
annotated source: perineurial glial cell
annotated property: definition
annotated target: Glial cell that forms part of the perineurial sheath forming the outer layer of the nervous system. These cells divide extensively to increase in number as the nervous system expands during development (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: perineurial glial cell
annotated property: hasExactSynonym
annotated target: PNG
database_cross_reference: FlyBase:FBrf0243081

sense organ
type: Class
equivalent class: Class
  intersection of: FBbt_00100313
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: BFO_0000040
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007692
subclass of: Restriction
  on property: capable of
  some values from: GO_0050906
definition: Multicellular anatomical structure with largely bona fide boundary that transduces some sensory stimulus to the nervous system.
database_cross_reference: UBERON:0000020
database_cross_reference: VFB:FBbt_00005155
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005155
in subset: FB gloss
in subset: cur
in subset: hidden assertion
in subset: larval OF

Axiom
annotated source: sense organ
annotated property: definition
annotated target: Multicellular anatomical structure with largely bona fide boundary that transduces some sensory stimulus to the nervous system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

mechanosensory sensory organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050974
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007687
subclass of: Restriction
  on property: capable of
  some values from: GO_0050974
definition: Any sense organ (FBbt:00005155) that is capable of some detection of mechanical stimulus involved in sensory perception (GO:0050974).
database_cross_reference: VFB:FBbt_00005156
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005156
in subset: cur

Axiom
annotated source: mechanosensory sensory organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is capable of some detection of mechanical stimulus involved in sensory perception (GO:0050974).
database_cross_reference: FBC:Autogenerated

chemosensory sensory organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050907
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007689
subclass of: Restriction
  on property: capable of
  some values from: GO_0050907
definition: Any sense organ (FBbt:00005155) that is capable of some detection of chemical stimulus involved in sensory perception (GO:0050907).
database_cross_reference: UBERON:0000005
database_cross_reference: VFB:FBbt_00005157
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005157
in subset: cur
in subset: larval OF

Axiom
annotated source: chemosensory sensory organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is capable of some detection of chemical stimulus involved in sensory perception (GO:0050907).
database_cross_reference: FlyBase:FBrf0068700

olfactory sensory organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050911
subclass of: chemosensory sensory organ
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007688
subclass of: Restriction
  on property: capable of
  some values from: GO_0050911
definition: Any sense organ (FBbt:00005155) that is capable of some detection of chemical stimulus involved in sensory perception of smell (GO:0050911).
database_cross_reference: UBERON:0002268
database_cross_reference: VFB:FBbt_00005158
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005158
in subset: cur
in subset: larval OF

Axiom
annotated source: olfactory sensory organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is capable of some detection of chemical stimulus involved in sensory perception of smell (GO:0050911).
database_cross_reference: FBC:Autogenerated

gustatory sensory organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050912
subclass of: chemosensory sensory organ
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007690
subclass of: Restriction
  on property: capable of
  some values from: GO_0050912
definition: Any sense organ (FBbt:00005155) that is capable of some detection of chemical stimulus involved in sensory perception of taste (GO:0050912).
database_cross_reference: UBERON:0003212
database_cross_reference: VFB:FBbt_00005159
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005159
in subset: cur

Axiom
annotated source: gustatory sensory organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is capable of some detection of chemical stimulus involved in sensory perception of taste (GO:0050912).
database_cross_reference: FBC:Autogenerated

photoreceptor
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050962
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047735
subclass of: Restriction
  on property: capable of
  some values from: GO_0050962
definition: A light sensitive sense organ.
database_cross_reference: UBERON:0000970
database_cross_reference: VFB:FBbt_00005162
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005162
in subset: FB gloss
in subset: cur

Axiom
annotated source: photoreceptor
annotated property: definition
annotated target: A light sensitive sense organ.
database_cross_reference: FBC:GG

sensory organ cell
type: Class
equivalent class: Class
  intersection of: FBbt_00100318
  intersection of: Restriction
    on property: overlaps
    some values from: sense organ
subclass of: FBbt_00100318
subclass of: Restriction
  on property: overlaps
  some values from: sense organ
definition: Any somatic cell (FBbt:00100318) that overlaps some sense organ (FBbt:00005155).
has OBO namespace: fly_anatomy.ontology
has related synonym: SOC
id: FBbt:00005163
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: sensory organ cell
annotated property: definition
annotated target: Any somatic cell (FBbt:00100318) that overlaps some sense organ (FBbt:00005155).
database_cross_reference: FBC:Autogenerated

external sensory organ precursor cell
type: Class
subclass of: FBbt_00052556
definition: Precursor cell that gives rise to at least one cell of an external sensory organ.
has broad synonym: es cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005164
in subset: cur

Axiom
annotated source: external sensory organ precursor cell
annotated property: definition
annotated target: Precursor cell that gives rise to at least one cell of an external sensory organ.
database_cross_reference: FlyBase:FBrf0111371

Axiom
annotated source: external sensory organ precursor cell
annotated property: hasBroadSynonym
annotated target: es cell
database_cross_reference: FlyBase:FBrf0045361

external sensory organ precursor cell I
type: Class
subclass of: sensory mother cell
subclass of: external sensory organ precursor cell
definition: First-order precursor cell: mother of all the clonally related cells of an external sensory organ.
has broad synonym: SOP
has exact synonym: external sensory organ sensory mother cell
has OBO namespace: fly_anatomy.ontology
has related synonym: SOPI
has related synonym: founder cell
id: FBbt:00005165
in subset: cur

Axiom
annotated source: external sensory organ precursor cell I
annotated property: definition
annotated target: First-order precursor cell: mother of all the clonally related cells of an external sensory organ.
database_cross_reference: FlyBase:FBrf0049554
database_cross_reference: FlyBase:FBrf0111371
database_cross_reference: FlyBase:FBrf0158845

Axiom
annotated source: external sensory organ precursor cell I
annotated property: hasBroadSynonym
annotated target: SOP
database_cross_reference: FlyBase:FBrf0241429

external sensory organ precursor cell IIb
type: Class
subclass of: external sensory organ precursor cell
subclass of: Restriction
  on property: develops from
  some values from: external sensory organ precursor cell I
definition: Second-order precursor cell that develops from an external sensory organ precursor cell I. In the microchaete lineage, it divides to give rise to the thecogen cell and the neuron of an external sensory organ (Gho et al., 1999; Hartenstein and Posakony, 1989). In the development of antennal olfactory sensilla, it produces two daughters, pNa and pNb, which each divide asymmetrically to produce up to four types of olfactory neuron per sensillum (Endo et al., 2012; Chai et al., 2019).
has exact synonym: SOPIIb
has exact synonym: pIIb
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005167
in subset: cur

Axiom
annotated source: external sensory organ precursor cell IIb
annotated property: definition
annotated target: Second-order precursor cell that develops from an external sensory organ precursor cell I. In the microchaete lineage, it divides to give rise to the thecogen cell and the neuron of an external sensory organ (Gho et al., 1999; Hartenstein and Posakony, 1989). In the development of antennal olfactory sensilla, it produces two daughters, pNa and pNb, which each divide asymmetrically to produce up to four types of olfactory neuron per sensillum (Endo et al., 2012; Chai et al., 2019).
database_cross_reference: FlyBase:FBrf0049554
database_cross_reference: FlyBase:FBrf0111371
database_cross_reference: FlyBase:FBrf0217319
database_cross_reference: FlyBase:FBrf0241429

Axiom
annotated source: external sensory organ precursor cell IIb
annotated property: hasExactSynonym
annotated target: pIIb
database_cross_reference: FlyBase:FBrf0241429

external sensory organ
type: Class
subclass of: sense organ
definition: Sensory organ that has external structures that detect mechanical or chemical stimuli.
database_cross_reference: UBERON:6005168
database_cross_reference: VFB:FBbt_00005168
has exact synonym: eo
has exact synonym: es
has OBO namespace: fly_anatomy.ontology
has related synonym: sensillum
id: FBbt:00005168
in subset: cur
in subset: larval OF

Axiom
annotated source: external sensory organ
annotated property: definition
annotated target: Sensory organ that has external structures that detect mechanical or chemical stimuli.
database_cross_reference: FlyBase:FBrf0064796

Axiom
annotated source: external sensory organ
annotated property: hasExactSynonym
annotated target: es
database_cross_reference: FlyBase:FBrf0064796

eo neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has sensory dendrite in
    some values from: FBbt_00007232
subclass of: FBbt_00052560
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
subclass of: Restriction
  on property: develops from
  some values from: external sensory organ precursor cell IIIb
subclass of: Restriction
  on property: has sensory dendrite in
  some values from: FBbt_00007232
definition: Sensory neuron that is part of an eo-sensillum and whose dendrite innervates the cuticular external sensory structure of that sensillum.
database_cross_reference: VFB:FBbt_00005174
has OBO namespace: fly_anatomy.ontology
has related synonym: Type I neuron
id: FBbt:00005174
in subset: cur
in subset: hidden assertion

Axiom
annotated source: eo neuron
annotated property: definition
annotated target: Sensory neuron that is part of an eo-sensillum and whose dendrite innervates the cuticular external sensory structure of that sensillum.
database_cross_reference: FlyBase:FBrf0049554
database_cross_reference: FlyBase:FBrf0111371

chaeta
type: Class
subclass of: FBbt_00007232
definition: A sensillum with a long, unicellular, setiform outgrowth that is strongly chitinized.
database_cross_reference: UBERON:6005177
database_cross_reference: VFB:FBbt_00005177
has exact synonym: sensillum chaeticum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005177
in subset: FB gloss
in subset: cur
comment: This term is sometimes used to refer to the 'bristle-like' outgrowth only, but is here used to refer to the entire sensillum of which it is a part.

Axiom
annotated source: chaeta
annotated property: definition
annotated target: A sensillum with a long, unicellular, setiform outgrowth that is strongly chitinized.
database_cross_reference: FlyBase:FBrf0111704
database_cross_reference: FlyBase:FBrf0166419

Axiom
annotated source: chaeta
annotated property: hasExactSynonym
annotated target: sensillum chaeticum
database_cross_reference: FlyBase:FBrf0111704

taste bristle
type: Class
equivalent class: Class
  intersection of: chaeta
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050912
subclass of: gustatory sensory organ
subclass of: chaeta
definition: Any bristle that is innervated by a gustatory receptor neuron. It has pores to allow food stimuli to reach the neuron.
database_cross_reference: VFB:FBbt_00005178
has OBO namespace: fly_anatomy.ontology
has related synonym: chemosensory chaeta
has related synonym: gs
has related synonym: gustatory sensillum
id: FBbt:00005178
in subset: cur

Axiom
annotated source: taste bristle
annotated property: definition
annotated target: Any bristle that is innervated by a gustatory receptor neuron. It has pores to allow food stimuli to reach the neuron.
database_cross_reference: FlyBase:FBrf0237124

Axiom
annotated source: taste bristle
annotated property: hasRelatedSynonym
annotated target: gs
database_cross_reference: FlyBase:FBrf0237124

Axiom
annotated source: taste bristle
annotated property: hasRelatedSynonym
annotated target: gustatory sensillum
database_cross_reference: FlyBase:FBrf0237124

mechanosensory chaeta
type: Class
equivalent class: Class
  intersection of: chaeta
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050974
subclass of: mechanosensory sensory organ
subclass of: chaeta
definition: Bristle that is innervated by a mechanosensory neuron that detects its movement due to wind, contact or other stimuli.
has broad synonym: es
has broad synonym: external sensillum
database_cross_reference: VFB:FBbt_00005181
has exact synonym: mechanosensory bristle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005181
in subset: cur

Axiom
annotated source: mechanosensory chaeta
annotated property: definition
annotated target: Bristle that is innervated by a mechanosensory neuron that detects its movement due to wind, contact or other stimuli.
database_cross_reference: FlyBase:FBrf0237124

Axiom
annotated source: mechanosensory chaeta
annotated property: hasBroadSynonym
annotated target: es
database_cross_reference: FlyBase:FBrf0237124

Axiom
annotated source: mechanosensory chaeta
annotated property: hasBroadSynonym
annotated target: external sensillum
database_cross_reference: FlyBase:FBrf0237124

Keilin organ
type: Class
subclass of: FBbt_00007232
subclass of: FBbt_00007244
subclass of: FBbt_00025990
subclass of: Restriction
  on property: part of
  some values from: FBbt_00052117
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048408
definition: A sensillum of the ventral sensory cluster group of the embryonic/larval thorax whose external sensory structure consists of a cluster of three hairs. It is innervated by 5 dendrites.
database_cross_reference: VFB:FBbt_00005198
has exact synonym: KO
has exact synonym: Keilin's organ
has OBO namespace: fly_anatomy.ontology
has related synonym: Fusstummelsinnesorgan
has related synonym: trihair
id: FBbt:00005198
in subset: cur

Axiom
annotated source: Keilin organ
annotated property: definition
annotated target: A sensillum of the ventral sensory cluster group of the embryonic/larval thorax whose external sensory structure consists of a cluster of three hairs. It is innervated by 5 dendrites.
database_cross_reference: FlyBase:FBrf0045359
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: Keilin organ
annotated property: hasExactSynonym
annotated target: KO
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: Keilin organ
annotated property: hasExactSynonym
annotated target: Keilin's organ
database_cross_reference: FlyBase:FBrf0089570

multidendritic neuron
type: Class
subclass of: sensory neuron
subclass of: FBbt_00059272
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
subclass of: Restriction
  on property: develops from
  some values from: multidendritic neuron precursor cell
definition: Sensory neuron of the peripheral nervous system that has multiple dendrites (Bodmer and Jan, 1987).
database_cross_reference: VFB:FBbt_00005209
has exact synonym: md neuron
has exact synonym: type II neuron
has exact synonym: type II-SN
has OBO namespace: fly_anatomy.ontology
has related synonym: md
id: FBbt:00005209
in subset: cur

Axiom
annotated source: multidendritic neuron
annotated property: definition
annotated target: Sensory neuron of the peripheral nervous system that has multiple dendrites (Bodmer and Jan, 1987).
database_cross_reference: FlyBase:FBrf0047289
database_cross_reference: FlyBase:FBrf0080250

Axiom
annotated source: multidendritic neuron
annotated property: hasExactSynonym
annotated target: type II-SN
database_cross_reference: FlyBase:FBrf0253566

multidendritic neuron precursor cell
type: Class
subclass of: FBbt_00052556
definition: A precursor cell that differentiates into a sensory neuron with multiple dendrites (Bodmer and Jan, 1987).
has broad synonym: md cell
has OBO namespace: fly_anatomy.ontology
has related synonym: multidendritic sensory organ precursor cell
id: FBbt:00005210
in subset: cur
comment: In the larva many md neurons are related to es neurons, suggesting that some of these may develop from es sensory mother cells (Brewster and Bodmer, 1995; Veling et al., 2019).

Axiom
annotated source: multidendritic neuron precursor cell
annotated property: definition
annotated target: A precursor cell that differentiates into a sensory neuron with multiple dendrites (Bodmer and Jan, 1987).
database_cross_reference: FlyBase:FBrf0047289
database_cross_reference: FlyBase:FBrf0083795
database_cross_reference: FlyBase:FBrf0244192

Axiom
annotated source: multidendritic neuron precursor cell
annotated property: hasBroadSynonym
annotated target: md cell
database_cross_reference: FlyBase:FBrf0047289

chordotonal organ
type: Class
subclass of: mechanosensory sensory organ
subclass of: FBbt_00007373
subclass of: Restriction
  on property: develops from
  some values from: chordotonal organ precursor cell
definition: Mechanosensory organ, generally attached to the body wall, spanning different parts of the exoskeleton. It consists of one or more scolopidia and detects tension or vibration.
database_cross_reference: UBERON:0001038
database_cross_reference: VFB:FBbt_00005215
has exact synonym: co
has exact synonym: scolopophorous organ
has exact synonym: sensilla scolopophora
has OBO namespace: fly_anatomy.ontology
has related synonym: ch
id: FBbt:00005215
in subset: FB gloss
in subset: cur

Axiom
annotated source: chordotonal organ
annotated property: definition
annotated target: Mechanosensory organ, generally attached to the body wall, spanning different parts of the exoskeleton. It consists of one or more scolopidia and detects tension or vibration.
database_cross_reference: FlyBase:FBrf0056378
database_cross_reference: FlyBase:FBrf0237124

Axiom
annotated source: chordotonal organ
annotated property: hasExactSynonym
annotated target: co
database_cross_reference: FlyBase:FBrf0237124

Axiom
annotated source: chordotonal organ
annotated property: hasExactSynonym
annotated target: scolopophorous organ
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: chordotonal organ
annotated property: hasExactSynonym
annotated target: sensilla scolopophora
database_cross_reference: FlyBase:FBrf0007735

chordotonal organ precursor cell
type: Class
subclass of: FBbt_00052556
definition: Precursor cell that gives rise to at least one cell of a chordotonal organ (Bodmer and Jan, 1987; Ghysen et al., 1986; zur Lage et al, 1997).
has broad synonym: ch cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005216
in subset: cur

Axiom
annotated source: chordotonal organ precursor cell
annotated property: definition
annotated target: Precursor cell that gives rise to at least one cell of a chordotonal organ (Bodmer and Jan, 1987; Ghysen et al., 1986; zur Lage et al, 1997).
database_cross_reference: FlyBase:FBrf0045361
database_cross_reference: FlyBase:FBrf0047289
database_cross_reference: FlyBase:FBrf0092876

Axiom
annotated source: chordotonal organ precursor cell
annotated property: hasBroadSynonym
annotated target: ch cell
database_cross_reference: FlyBase:FBrf0045361

scolopidium
type: Class
subclass of: mechanosensory sensory organ
subclass of: FBbt_00007233
subclass of: Restriction
  on property: part of
  some values from: chordotonal organ
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00052557
definition: Sensillum unit of a chordotonal organ, consisting of a cap cell, a ligament cell, a scolopale cell (sheath cell) and the dendrites of one or more sensory neurons. The basal end of the scolopidium is held in place by a ligament cell, usually attached to the integument. The dendrite of each sensory neuron has a cilium projecting from its tip through the scolopale, a rod like structure secreted by the scolopale cell. The cilium terminates in a dendritic cap, embedded in the cap cell. The cap cell is attached to the integument.
database_cross_reference: VFB:FBbt_00005217
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005217
in subset: cur

Axiom
annotated source: scolopidium
annotated property: definition
annotated target: Sensillum unit of a chordotonal organ, consisting of a cap cell, a ligament cell, a scolopale cell (sheath cell) and the dendrites of one or more sensory neurons. The basal end of the scolopidium is held in place by a ligament cell, usually attached to the integument. The dendrite of each sensory neuron has a cilium projecting from its tip through the scolopale, a rod like structure secreted by the scolopale cell. The cilium terminates in a dendritic cap, embedded in the cap cell. The cap cell is attached to the integument.
database_cross_reference: FlyBase:FBrf0056378
database_cross_reference: FlyBase:FBrf0098208
database_cross_reference: FlyBase:FBrf0239412

chordotonal neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has sensory dendrite in
    some values from: chordotonal organ
subclass of: sensory organ cell
subclass of: mechanosensory neuron
subclass of: FBbt_00059272
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
subclass of: Restriction
  on property: develops from
  some values from: chordotonal organ precursor cell
subclass of: Restriction
  on property: has sensory dendrite in
  some values from: scolopidium
definition: Sensory neuron of a chordotonal organ. The tip of its dendrite is associated with a rod-like structure called a scolopale rod.
database_cross_reference: VFB:FBbt_00005222
has exact synonym: ch neuron
has exact synonym: scolopidial neuron
has OBO namespace: fly_anatomy.ontology
has related synonym: Type II neuron
id: FBbt:00005222
in subset: cur
in subset: hidden assertion

Axiom
annotated source: chordotonal neuron
annotated property: definition
annotated target: Sensory neuron of a chordotonal organ. The tip of its dendrite is associated with a rod-like structure called a scolopale rod.
database_cross_reference: FlyBase:FBrf0056378
database_cross_reference: FlyBase:FBrf0111704

midgut primordium
type: Class
subclass of: primordium
definition: Any primordium that is a precursor of all or some part of the larval or adult midgut.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005246
in subset: cur

Axiom
annotated source: midgut primordium
annotated property: definition
annotated target: Any primordium that is a precursor of all or some part of the larval or adult midgut.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

late stomodeal invagination
type: Class
subclass of: stomodeal invagination
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: early stomodeal invagination
definition: Stomodeal invagination in its later phase of growth during stages 11-12 as it extends caudally (Campos-Ortega and Hartenstein, 1997).
has exact synonym: stomodeal invagination late
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005252
in subset: cur

Axiom
annotated source: late stomodeal invagination
annotated property: definition
annotated target: Stomodeal invagination in its later phase of growth during stages 11-12 as it extends caudally (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

germinal proliferation center
type: Class
subclass of: multi-tissue structure
subclass of: FBbt_00048490
subclass of: Restriction
  on property: part of
  some values from: testis
definition: Structure formed by the male germline stem cells, cyst progenitor cells and the hub around which they are clustered and to which they are attached. It is located at the apical (blind) end of the testis.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005259
in subset: FlyTed
in subset: cur

Axiom
annotated source: germinal proliferation center
annotated property: definition
annotated target: Structure formed by the male germline stem cells, cyst progenitor cells and the hub around which they are clustered and to which they are attached. It is located at the apical (blind) end of the testis.
database_cross_reference: FlyBase:FBrf0024468
database_cross_reference: FlyBase:FBrf0064778

pre-blastoderm embryo
type: Class
subclass of: embryo
definition: Embryo prior to the formation of the syncitial blastoderm, shortly after nuclear cycle 9 (Foe and Alberts, 1983; Jaeger et al., 2012). This period lasts from fertilization to the end of embryonic stage 3 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00005290
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005290

Axiom
annotated source: pre-blastoderm embryo
annotated property: definition
annotated target: Embryo prior to the formation of the syncitial blastoderm, shortly after nuclear cycle 9 (Foe and Alberts, 1983; Jaeger et al., 2012). This period lasts from fertilization to the end of embryonic stage 3 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0039741
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0220623

stage 1 embryo
type: Class
subclass of: cleavage stage embryo
subclass of: pre-blastoderm embryo
definition: Nuclear divisions 1 and 2. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005291
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 1 embryo
annotated property: definition
annotated target: Nuclear divisions 1 and 2. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

stage 2 embryo
type: Class
subclass of: cleavage stage embryo
subclass of: pre-blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 1 embryo
definition: Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005293
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 2 embryo
annotated property: definition
annotated target: Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).
database_cross_reference: FlyBase:FBrf0089570

stage 3 embryo
type: Class
subclass of: cleavage stage embryo
subclass of: syncytial blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 2 embryo
definition: Nuclear division 9. The cleavage nuclei complete there migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005301
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 3 embryo
annotated property: definition
annotated target: Nuclear division 9. The cleavage nuclei complete there migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

blastoderm embryo
type: Class
subclass of: embryo
definition: Embryo during the blastoderm stage, where most nuclei are found at the cortex (periphery) of the embryo (Foe and Alberts, 1983; Jaeger et al., 2012). The blastoderm stage begins shortly after completion of the ninth cleavage division and lasts until the onset of gastrulation, including cleavage cycles 10-14A (Foe and Alberts, 1983; Jaeger et al., 2012). This corresponds to embryonic stages 4 (syncitial blastoderm stage) and 5 (cellular blastoderm stage) (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00005304
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005304

Axiom
annotated source: blastoderm embryo
annotated property: definition
annotated target: Embryo during the blastoderm stage, where most nuclei are found at the cortex (periphery) of the embryo (Foe and Alberts, 1983; Jaeger et al., 2012). The blastoderm stage begins shortly after completion of the ninth cleavage division and lasts until the onset of gastrulation, including cleavage cycles 10-14A (Foe and Alberts, 1983; Jaeger et al., 2012). This corresponds to embryonic stages 4 (syncitial blastoderm stage) and 5 (cellular blastoderm stage) (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0039741
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0220623

syncytial blastoderm embryo
type: Class
subclass of: blastoderm embryo
definition: A blastoderm embryo prior to cellularization (corresponds to embryonic stages 3 and 4).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005305
in subset: cur
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: syncytial blastoderm embryo
annotated property: definition
annotated target: A blastoderm embryo prior to cellularization (corresponds to embryonic stages 3 and 4).
database_cross_reference: FBC:GG
database_cross_reference: https://orcid.org/0000-0002-7073-9172

stage 4 embryo
type: Class
subclass of: cleavage stage embryo
subclass of: syncytial blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 3 embryo
definition: Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005306
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 4 embryo
annotated property: definition
annotated target: Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

stage 5 embryo
type: Class
subclass of: blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 4 embryo
definition: Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees C: approximately 40 minutes (130-170 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
has related synonym: cellular blastoderm embryo
id: FBbt:00005311
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 5 embryo
annotated property: definition
annotated target: Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees C: approximately 40 minutes (130-170 minutes after egg laying).
database_cross_reference: FBC:MA
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: https://orcid.org/0000-0002-7073-9172

gastrula embryo
type: Class
subclass of: embryo
subclass of: Restriction
  on property: develops from
  some values from: blastoderm embryo
definition: Embryo that is in the process of gastrulation (encompassing embryonic stages 6-8), during which complex morphogenetic movements result in the formation of the three germ layers; ectoderm, mesoderm and endoderm (Hartenstein, 1993).
database_cross_reference: FBdv:00005317
database_cross_reference: UBERON:0004734
has exact synonym: gastrulation stage embryo
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005317

Axiom
annotated source: gastrula embryo
annotated property: definition
annotated target: Embryo that is in the process of gastrulation (encompassing embryonic stages 6-8), during which complex morphogenetic movements result in the formation of the three germ layers; ectoderm, mesoderm and endoderm (Hartenstein, 1993).
database_cross_reference: FlyBase:FBrf0064803

stage 6 embryo
type: Class
subclass of: gastrula embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 5 embryo
definition: Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005318
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 6 embryo
annotated property: definition
annotated target: Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

stage 7 embryo
type: Class
subclass of: gastrula embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 6 embryo
definition: Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' carrying the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005319
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 7 embryo
annotated property: definition
annotated target: Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' carrying the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: https://orcid.org/0000-0002-7073-9172

extended germ band embryo
type: Class
subclass of: embryo
subclass of: Restriction
  on property: develops from
  some values from: gastrula embryo
definition: Embryo during stages 9-12.
database_cross_reference: FBdv:00005321
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005321

Axiom
annotated source: extended germ band embryo
annotated property: definition
annotated target: Embryo during stages 9-12.
database_cross_reference: FlyBase:FBrf0229323
database_cross_reference: https://orcid.org/0000-0002-7073-9172

stage 8 embryo
type: Class
subclass of: gastrula embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 7 embryo
definition: Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005322
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 8 embryo
annotated property: definition
annotated target: Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: https://orcid.org/0000-0002-7073-9172

stomodeal invagination
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: extended germ band embryo
definition: Infolding of the anteroventral embryo that arises during stage 10 (Campos-Ortega and Hartenstein, 1997). Its formation begins when cells surrounding the stomodeal anlage, which consists of a plate of tall cylindrical cells just prior to invagination, divide synchronously (Campos-Ortega and Hartenstein, 1997). The invaginated cells divide immediately afterwards, forming a monolayered epithelium (Campos-Ortega and Hartenstein, 1997). It is initially oriented perpendicular to the horizontal plane, but progressively bends towards the ventral plane (Campos-Ortega and Hartenstein, 1997). It grows caudally by cell divisions and incorporation of neighboring ectodermal cells (Campos-Ortega and Hartenstein, 1997).
has broad synonym: stomodeum
has OBO namespace: fly_anatomy.ontology
has related synonym: anterior midgut invagination
id: FBbt:00005326
in subset: cur

Axiom
annotated source: stomodeal invagination
annotated property: definition
annotated target: Infolding of the anteroventral embryo that arises during stage 10 (Campos-Ortega and Hartenstein, 1997). Its formation begins when cells surrounding the stomodeal anlage, which consists of a plate of tall cylindrical cells just prior to invagination, divide synchronously (Campos-Ortega and Hartenstein, 1997). The invaginated cells divide immediately afterwards, forming a monolayered epithelium (Campos-Ortega and Hartenstein, 1997). It is initially oriented perpendicular to the horizontal plane, but progressively bends towards the ventral plane (Campos-Ortega and Hartenstein, 1997). It grows caudally by cell divisions and incorporation of neighboring ectodermal cells (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: stomodeal invagination
annotated property: hasBroadSynonym
annotated target: stomodeum
database_cross_reference: FlyBase:FBrf0089570

dorsal closure embryo
type: Class
subclass of: embryo
subclass of: Restriction
  on property: develops from
  some values from: late extended germ band embryo
definition: Embryo during the dorsal closure stage, which corresponds to stages 13-15 (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). Dorsal closure occurs by extension of the dorsal epidermal primordium on either side, leading to fusion at the dorsal midline (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00005331
has OBO namespace: fly_anatomy.ontology
has related synonym: contracted germ band embryo
has related synonym: head involution embryo
id: FBbt:00005331

Axiom
annotated source: dorsal closure embryo
annotated property: definition
annotated target: Embryo during the dorsal closure stage, which corresponds to stages 13-15 (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). Dorsal closure occurs by extension of the dorsal epidermal primordium on either side, leading to fusion at the dorsal midline (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570

late embryo
type: Class
subclass of: embryo
subclass of: Restriction
  on property: develops from
  some values from: dorsal closure embryo
definition: Embryo during stages 16 and 17.
database_cross_reference: FBdv:00005333
database_cross_reference: UBERON:0000323
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005333

Axiom
annotated source: late embryo
annotated property: definition
annotated target: Embryo during stages 16 and 17.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

antennal segment 2 sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: part of
    some values from: second segment of antenna
subclass of: adult antennal sense organ
subclass of: Restriction
  on property: part of
  some values from: second segment of antenna
definition: Any sense organ (FBbt:00005155) that is part of some second segment of antenna (FBbt:00004514).
database_cross_reference: VFB:FBbt_00005377
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005377
in subset: cur

Axiom
annotated source: antennal segment 2 sense organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is part of some second segment of antenna (FBbt:00004514).
database_cross_reference: FBC:Autogenerated

foregut
type: Class
subclass of: multi-tissue structure
subclass of: FBbt_00100315
definition: An anterior part of the alimentary canal derived from the ectoderm. It is lined on its luminal side by a impermeable cuticle. The proventriculus (cardia) is located at the junction between the foregut and midgut.
database_cross_reference: UBERON:0001041
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005379
in subset: FB gloss
in subset: cur

Axiom
annotated source: foregut
annotated property: definition
annotated target: An anterior part of the alimentary canal derived from the ectoderm. It is lined on its luminal side by a impermeable cuticle. The proventriculus (cardia) is located at the junction between the foregut and midgut.
database_cross_reference: FBC:GG

pharynx
type: Class
subclass of: FBbt_00100315
subclass of: Restriction
  on property: part of
  some values from: foregut
definition: Section of the foregut anterior to the esophagus.
database_cross_reference: UBERON:6005380
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005380
in subset: cur

Axiom
annotated source: pharynx
annotated property: definition
annotated target: Section of the foregut anterior to the esophagus.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

salivary gland
type: Class
subclass of: FBbt_00100317
subclass of: Restriction
  on property: part of
  some values from: foregut
subclass of: Restriction
  on property: capable of
  some values from: GO_0046541
definition: Paired secretory organ connected to the atrium via the salivary duct. It is essentially composed of two cell types: cuboidal epithelial duct cells that form tubes connecting the secretory cells to the larval mouth; and secretory cells that synthesize and secrete high levels of protein (Andrew et al., 2000).
database_cross_reference: UBERON:0001044
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005382
in subset: cur

Axiom
annotated source: salivary gland
annotated property: definition
annotated target: Paired secretory organ connected to the atrium via the salivary duct. It is essentially composed of two cell types: cuboidal epithelial duct cells that form tubes connecting the secretory cells to the larval mouth; and secretory cells that synthesize and secrete high levels of protein (Andrew et al., 2000).
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0126988

midgut
type: Class
subclass of: multi-tissue structure
subclass of: FBbt_00100315
definition: The part of the alimentary canal extending posteriorly from the proventriculus to close to the point where the Malpighian tubes are attached and where the hindgut starts. It is predominantly derived from the endoderm and it is lined by the peritrophic membrane.
database_cross_reference: UBERON:0001045
has exact synonym: ventriculus
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005383
in subset: FB gloss
in subset: cur

Axiom
annotated source: midgut
annotated property: definition
annotated target: The part of the alimentary canal extending posteriorly from the proventriculus to close to the point where the Malpighian tubes are attached and where the hindgut starts. It is predominantly derived from the endoderm and it is lined by the peritrophic membrane.
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0166419

Axiom
annotated source: midgut
annotated property: hasExactSynonym
annotated target: ventriculus
database_cross_reference: FlyBase:FBrf0007732

hindgut
type: Class
subclass of: multi-tissue structure
subclass of: FBbt_00100315
subclass of: Restriction
  on property: expresses
  some values from: FBgn0011723
definition: A posterior part of the alimentary canal derived from the ectoderm. It extends anteriorly from close to the point of attachment of the Malpighian tubules to the anus. It is lined on its luminal side by an impermeable cuticle (Skaer, 1993).
database_cross_reference: UBERON:0001046
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005384
in subset: FB gloss
in subset: cur
comment: Adult and larval hindguts express the transcription factor brachyenteron (Sawyer et al., 2017).

Axiom
annotated source: hindgut
annotated property: definition
annotated target: A posterior part of the alimentary canal derived from the ectoderm. It extends anteriorly from close to the point of attachment of the Malpighian tubules to the anus. It is lined on its luminal side by an impermeable cuticle (Skaer, 1993).
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0064792

glomerulus
type: Class
subclass of: FBbt_00040006
definition: Roundish subunit structure of synaptic neuropil, often ensheathed by glial lamellae and reflecting the terminal arborization domain(s) of one or more neurons.
database_cross_reference: UBERON:0001047
database_cross_reference: VFB:FBbt_00005386
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005386
in subset: FB gloss
in subset: cur
in subset: larval OF

embryonic nervous system of thorax
type: Class
subclass of: FBbt_00007332
subclass of: Restriction
  on property: part of
  some values from: embryonic thorax
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval nervous system
definition: The portion of the embryonic nervous system that is part of the thorax.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005387
in subset: cur

Axiom
annotated source: embryonic nervous system of thorax
annotated property: definition
annotated target: The portion of the embryonic nervous system that is part of the thorax.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic nervous system of abdomen
type: Class
subclass of: FBbt_00007332
subclass of: Restriction
  on property: part of
  some values from: embryonic abdomen
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval nervous system
definition: The portion of the embryonic nervous system that is part of the abdomen.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005388
in subset: cur

Axiom
annotated source: embryonic nervous system of abdomen
annotated property: definition
annotated target: The portion of the embryonic nervous system that is part of the abdomen.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

presumptive embryonic/larval integumentary system
type: Class
subclass of: presumptive embryonic/larval system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval integumentary system.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic integumentary system
id: FBbt:00005392
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: presumptive embryonic/larval integumentary system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval integumentary system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: presumptive embryonic/larval integumentary system
annotated property: hasRelatedSynonym
annotated target: embryonic integumentary system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

larval integumentary system
type: Class
equivalent class: Class
  intersection of: integumentary system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: integumentary system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Integumentary system of the late embryo or larva.
database_cross_reference: UBERON:6005393
has exact synonym: embryonic/larval integumentary system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005393
in subset: cur

Axiom
annotated source: larval integumentary system
annotated property: definition
annotated target: Integumentary system of the late embryo or larva.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult integumentary system
type: Class
equivalent class: Class
  intersection of: integumentary system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: integumentary system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Integumentary system of the adult.
has alternative id: FBbt:00004474
database_cross_reference: UBERON:6005396
has exact synonym: adult integument
has OBO namespace: fly_anatomy.ontology
has related synonym: adult external
id: FBbt:00005396
in subset: cur

Axiom
annotated source: adult integumentary system
annotated property: definition
annotated target: Integumentary system of the adult.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic epidermis
type: Class
subclass of: epidermis
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval integumentary system
definition: Epidermis of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005397
in subset: cur

Axiom
annotated source: embryonic epidermis
annotated property: definition
annotated target: Epidermis of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic/larval epidermis
type: Class
subclass of: epidermis
subclass of: Restriction
  on property: part of
  some values from: larval integumentary system
subclass of: Restriction
  on property: develops from
  some values from: embryonic epidermis
definition: Epidermis of the late embryo or larva.
has exact synonym: larval epidermis
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005398
in subset: cur

Axiom
annotated source: embryonic/larval epidermis
annotated property: definition
annotated target: Epidermis of the late embryo or larva.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult epidermis
type: Class
subclass of: epidermis
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: adult integumentary system
subclass of: Restriction
  on property: develops from
  some values from: imaginal disc
definition: Epidermis of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005401
in subset: cur

Axiom
annotated source: adult epidermis
annotated property: definition
annotated target: Epidermis of the adult.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

mushroom body vertical lobe
type: Class
subclass of: FBbt_00040007
subclass of: FBbt_00049824
subclass of: Restriction
  on property: part of
  some values from: lobe system of mushroom body
definition: Bundle of Kenyon cell projections that arises from the anterior end of the pedunculus and projects dorsally. It consists of two components: the alpha lobe and alpha' lobe.
database_cross_reference: VFB:FBbt_00005407
has exact synonym: VL
has exact synonym: dorsal lobe of mushroom body
has exact synonym: vertical branch of mushroom body
has exact synonym: vertical lobe of mushroom body
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal lobe
id: FBbt:00005407
in subset: cur

Axiom
annotated source: mushroom body vertical lobe
annotated property: definition
annotated target: Bundle of Kenyon cell projections that arises from the anterior end of the pedunculus and projects dorsally. It consists of two components: the alpha lobe and alpha' lobe.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00005407

Axiom
annotated source: mushroom body vertical lobe
annotated property: hasExactSynonym
annotated target: VL
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

mushroom body medial lobe
type: Class
subclass of: FBbt_00040007
subclass of: FBbt_00049824
subclass of: Restriction
  on property: part of
  some values from: lobe system of mushroom body
definition: A bundle of Kenyon cell projections that arises from the anterior end of the pedunculus and projects medially. It consists of three components: the beta lobe, beta' lobe and gamma lobe.
has alternative id: FBbt:00003692
database_cross_reference: VFB:FBbt_00005408
has exact synonym: ML
has exact synonym: horizontal lobe of mushroom body
has exact synonym: medial branch of mushroom body
has exact synonym: medial lobe of mushroom body
has OBO namespace: fly_anatomy.ontology
has related synonym: medial lobe
id: FBbt:00005408
in subset: BrainName
in subset: cur

Axiom
annotated source: mushroom body medial lobe
annotated property: definition
annotated target: A bundle of Kenyon cell projections that arises from the anterior end of the pedunculus and projects medially. It consists of three components: the beta lobe, beta' lobe and gamma lobe.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00005408

Axiom
annotated source: mushroom body medial lobe
annotated property: hasExactSynonym
annotated target: ML
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

anlage in statu nascendi
type: Class
subclass of: developing embryonic structure
definition: Domain that is in the process of forming an anlage and does not yet coincide 1:1 with a mature structure. These domains can be identified based on the expression of genes characteristic of the corresponding anlagen and are typically found in the early blastoderm.
has OBO namespace: fly_anatomy.ontology
has related synonym: A0
id: FBbt:00005413
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: anlage in statu nascendi
annotated property: definition
annotated target: Domain that is in the process of forming an anlage and does not yet coincide 1:1 with a mature structure. These domains can be identified based on the expression of genes characteristic of the corresponding anlagen and are typically found in the early blastoderm.
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0178740

central brain anlage in statu nascendi
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: stage 5 embryo
subclass of: Restriction
  on property: part of
  some values from: FBbt_01000119
definition: Anlage in statu nascendi of the embryonic central brain in a stage 5 embryo. It will give rise to the central brain anlage.
has exact synonym: Asn CenBr
has OBO namespace: fly_anatomy.ontology
has related synonym: A0ProcEC
has related synonym: procephalic ectoderm anlage in statu nascendi
id: FBbt:00005415
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: central brain anlage in statu nascendi
annotated property: definition
annotated target: Anlage in statu nascendi of the embryonic central brain in a stage 5 embryo. It will give rise to the central brain anlage.
database_cross_reference: FBC:VH

Axiom
annotated source: central brain anlage in statu nascendi
annotated property: hasExactSynonym
annotated target: Asn CenBr
database_cross_reference: https://orcid.org/0000-0002-7073-9172

foregut anlage in statu nascendi
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: stage 5 embryo
subclass of: Restriction
  on property: part of
  some values from: FBbt_01000119
definition: Anlage in statu nascendi of the foregut in a stage 5 embryo that will give rise to the foregut anlage.
has exact synonym: Asn FoG
has OBO namespace: fly_anatomy.ontology
has related synonym: A0FoG
id: FBbt:00005423
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: foregut anlage in statu nascendi
annotated property: definition
annotated target: Anlage in statu nascendi of the foregut in a stage 5 embryo that will give rise to the foregut anlage.
database_cross_reference: FBC:VH

Axiom
annotated source: foregut anlage in statu nascendi
annotated property: hasExactSynonym
annotated target: Asn FoG
database_cross_reference: https://orcid.org/0000-0002-7073-9172

hindgut anlage in statu nascendi
type: Class
subclass of: anlage in statu nascendi
subclass of: Restriction
  on property: part of
  some values from: stage 5 embryo
definition: Anlage in statu nascendi of the hindgut in a stage 5 embryo that will give rise to the hindgut anlage.
has exact synonym: Asn iHiGP
has OBO namespace: fly_anatomy.ontology
has related synonym: A0HiGP
id: FBbt:00005424
in subset: cur

Axiom
annotated source: hindgut anlage in statu nascendi
annotated property: definition
annotated target: Anlage in statu nascendi of the hindgut in a stage 5 embryo that will give rise to the hindgut anlage.
database_cross_reference: FBC:VH

Axiom
annotated source: hindgut anlage in statu nascendi
annotated property: hasExactSynonym
annotated target: Asn iHiGP
database_cross_reference: https://orcid.org/0000-0001-5948-3092

visual anlage in statu nascendi
type: Class
subclass of: anlage in statu nascendi
subclass of: Restriction
  on property: part of
  some values from: stage 5 embryo
subclass of: Restriction
  on property: part of
  some values from: FBbt_01000119
definition: Anlage in statu nascendi of the visual system in a stage 5 embryo that will give rise to the visual system anlage.
has exact synonym: Asn VisSys
has OBO namespace: fly_anatomy.ontology
has related synonym: A0Vis
id: FBbt:00005425
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: visual anlage in statu nascendi
annotated property: definition
annotated target: Anlage in statu nascendi of the visual system in a stage 5 embryo that will give rise to the visual system anlage.
database_cross_reference: FBC:VH

Axiom
annotated source: visual anlage in statu nascendi
annotated property: hasExactSynonym
annotated target: Asn VisSys
database_cross_reference: https://orcid.org/0000-0002-7073-9172

anlage
type: Class
subclass of: portion of tissue
subclass of: developing material anatomical entity
definition: Population of contiguous cells, typically arranged in one plane, that is morphologically indistinct from surrounding cells, but already corresponds to a later organ/tissue and can be identified based on gene expression or lineage tracing (Tomancak et al., 2002; Hartenstein, 2004).
database_cross_reference: UBERON:0007688
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005426
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: anlage
annotated property: definition
annotated target: Population of contiguous cells, typically arranged in one plane, that is morphologically indistinct from surrounding cells, but already corresponds to a later organ/tissue and can be identified based on gene expression or lineage tracing (Tomancak et al., 2002; Hartenstein, 2004).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0178740

ectoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: develops into
  some values from: ectoderm
definition: Cells of the early embryo that will become the ectoderm following gastrulation (Campos-Ortega and Hartenstein, 1997). It remains at the surface of the embryo as the endodermal and mesodermal anlagen invaginate (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:6005427
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005427
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ectoderm anlage
annotated property: definition
annotated target: Cells of the early embryo that will become the ectoderm following gastrulation (Campos-Ortega and Hartenstein, 1997). It remains at the surface of the embryo as the endodermal and mesodermal anlagen invaginate (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0244630

dorsal ectoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: ectoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: dorsal ectoderm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005428
in subset: cur

foregut anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: anterior ectoderm
subclass of: Restriction
  on property: develops from
  some values from: foregut anlage in statu nascendi
subclass of: Restriction
  on property: develops into
  some values from: embryonic foregut
definition: Anlage of the embryonic foregut.
has OBO namespace: fly_anatomy.ontology
has related synonym: AFoG
id: FBbt:00005431
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: foregut anlage
annotated property: definition
annotated target: Anlage of the embryonic foregut.
database_cross_reference: FBC:VH

salivary gland duct anlage
type: Class
subclass of: anlage
subclass of: FBbt_00025993
subclass of: Restriction
  on property: develops into
  some values from: salivary gland duct primordium
definition: A(n) anlage that develops into some salivary gland duct primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: A SalD
id: FBbt:00005432
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: salivary gland duct anlage
annotated property: definition
annotated target: A(n) anlage that develops into some salivary gland duct primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: salivary gland duct anlage
annotated property: hasRelatedSynonym
annotated target: A SalD
database_cross_reference: https://orcid.org/0000-0002-7073-9172

visual anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: anterior ectoderm
subclass of: Restriction
  on property: part of
  some values from: gastrula embryo
subclass of: Restriction
  on property: develops from
  some values from: visual anlage in statu nascendi
subclass of: Restriction
  on property: develops into
  some values from: visual primordium
definition: Anlage of the visual system in the gastrula embryo that will give rise to the visual primordium.
has broad synonym: eye field
has exact synonym: A VisSys
has OBO namespace: fly_anatomy.ontology
has related synonym: AVis
id: FBbt:00005434
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: visual anlage
annotated property: definition
annotated target: Anlage of the visual system in the gastrula embryo that will give rise to the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0141490

Axiom
annotated source: visual anlage
annotated property: hasBroadSynonym
annotated target: eye field
database_cross_reference: FlyBase:FBrf0141490

Axiom
annotated source: visual anlage
annotated property: hasExactSynonym
annotated target: A VisSys
database_cross_reference: https://orcid.org/0000-0002-7073-9172

endoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: develops into
  some values from: endoderm
definition: Contiguous region of early embryonic cells that will invaginate during gastrulation to form a region of the endoderm (Campos-Ortega and Hartenstein, 1997).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005435
in subset: cur

Axiom
annotated source: endoderm anlage
annotated property: definition
annotated target: Contiguous region of early embryonic cells that will invaginate during gastrulation to form a region of the endoderm (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831

trunk mesoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: mesoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: trunk mesoderm
definition: A(n) anlage that develops into some trunk mesoderm.
has OBO namespace: fly_anatomy.ontology
has related synonym: Asn/A TrMes
id: FBbt:00005436
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: trunk mesoderm anlage
annotated property: definition
annotated target: A(n) anlage that develops into some trunk mesoderm.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: trunk mesoderm anlage
annotated property: hasRelatedSynonym
annotated target: Asn/A TrMes
database_cross_reference: https://orcid.org/0000-0002-7073-9172

circulatory system primordium
type: Class
equivalent class: Class
  intersection of: primordium
  intersection of: Restriction
    on property: develops into
    some values from: Class
      intersection of: FBbt_10000000
      intersection of: Restriction
        on property: part of
        some values from: circulatory system
subclass of: primordium
subclass of: Restriction
  on property: develops into
  some values from: Class
    intersection of: FBbt_10000000
    intersection of: Restriction
      on property: part of
      some values from: circulatory system
definition: Any primordium (FBbt:00005495) that develops into is part of some anatomical entity (FBbt:10000000) that is part of some circulatory system (FBbt:00005057).
database_cross_reference: UBERON:6005461
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic/larval circulatory system specific anlage
id: FBbt:00005461
in subset: cur

Axiom
annotated source: circulatory system primordium
annotated property: definition
annotated target: Any primordium (FBbt:00005495) that develops into is part of some anatomical entity (FBbt:10000000) that is part of some circulatory system (FBbt:00005057).
database_cross_reference: FBC:Autogenerated

gonadal sheath proper primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: somatic trunk mesoderm derivative
subclass of: FBbt_00026002
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: fat body/gonad primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic/larval gonadal sheath muscle cell
definition: The primordium of the gonadal sheath. This arises from clusters of cells in parasegments 10, 11 and 12 of the dorsal branch of the fat body/gonad primordium which split off during stage 14 and then cluster around the germ cells.
has narrow synonym: SGP
has narrow synonym: somatic gonadal precursor
has OBO namespace: fly_anatomy.ontology
has related synonym: gonadal mesoderm
has related synonym: gonadal sheath specific anlage
id: FBbt:00005473
in subset: cur

Axiom
annotated source: gonadal sheath proper primordium
annotated property: definition
annotated target: The primordium of the gonadal sheath. This arises from clusters of cells in parasegments 10, 11 and 12 of the dorsal branch of the fat body/gonad primordium which split off during stage 14 and then cluster around the germ cells.
database_cross_reference: FlyBase:FBrf0092473

Axiom
annotated source: gonadal sheath proper primordium
annotated property: hasNarrowSynonym
annotated target: SGP
database_cross_reference: FlyBase:FBrf0092473

Axiom
annotated source: gonadal sheath proper primordium
annotated property: hasNarrowSynonym
annotated target: somatic gonadal precursor
database_cross_reference: FlyBase:FBrf0092473

Axiom
annotated source: gonadal sheath proper primordium
annotated property: hasRelatedSynonym
annotated target: gonadal sheath specific anlage
database_cross_reference: FBC:VH

embryonic leading edge cell primordium
type: Class
subclass of: dorsal ectoderm derivative
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: dorsal epidermis primordium
has OBO namespace: fly_anatomy.ontology
has related synonym: A EdCe
has related synonym: embryonic leading edge cell specific anlage
id: FBbt:00005475
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic leading edge cell primordium
annotated property: hasRelatedSynonym
annotated target: A EdCe
database_cross_reference: https://orcid.org/0000-0002-7073-9172

primordium
type: Class
subclass of: developing material anatomical entity
subclass of: Restriction
  on property: develops from
  some values from: anlage
definition: Precursor structure that can be recognized based on its distinct morphology and will give rise to one or more differentiated structures (Tomancak et al., 2002; Hartenstein, 2004). It develops from an anlage and may contain smaller anlage and primordia that will produce substructures (Tomancak et al., 2002).
database_cross_reference: UBERON:0001048
has OBO namespace: fly_anatomy.ontology
has related synonym: P
has related synonym: placode
id: FBbt:00005495
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: primordium
annotated property: definition
annotated target: Precursor structure that can be recognized based on its distinct morphology and will give rise to one or more differentiated structures (Tomancak et al., 2002; Hartenstein, 2004). It develops from an anlage and may contain smaller anlage and primordia that will produce substructures (Tomancak et al., 2002).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0178740

prothoracic gland primordium
type: Class
subclass of: dorsal ectoderm derivative
subclass of: FBbt_00017009
subclass of: Restriction
  on property: develops from
  some values from: dorsal sensory complex primordium
subclass of: Restriction
  on property: develops into
  some values from: prothoracic gland
definition: The primordium that will form the embryonic/larval prothoracic gland, a substructure of the embryonic/larval ring gland. It originates in the dorsal ectoderm of T1, from which it segregates during stage 15 to form bilateral clusters near the heart precursors. In late embryogenesis, it partially fuses with the corpus allatum.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005497
in subset: cur

Axiom
annotated source: prothoracic gland primordium
annotated property: definition
annotated target: The primordium that will form the embryonic/larval prothoracic gland, a substructure of the embryonic/larval ring gland. It originates in the dorsal ectoderm of T1, from which it segregates during stage 15 to form bilateral clusters near the heart precursors. In late embryogenesis, it partially fuses with the corpus allatum.
database_cross_reference: FlyBase:FBrf0089570

Malpighian tubule main body primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: Malpighian tubule primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic posterior Malpighian tubule
definition: A(n) primordium that develops into some embryonic posterior Malpighian tubule. It develops from some Malpighian tubule primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: P1 MalTB
id: FBbt:00005501
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: Malpighian tubule main body primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic posterior Malpighian tubule. It develops from some Malpighian tubule primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: Malpighian tubule main body primordium
annotated property: hasRelatedSynonym
annotated target: P1 MalTB
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Malpighian tubule tip cell primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: Malpighian tubule primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic Malpighian tubule tip cell
definition: A(n) primordium that develops into some embryonic Malpighian tubule tip cell. It develops from some Malpighian tubule primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: Malpighian tubule tip cell specific anlage
has related synonym: P1 MalTT
id: FBbt:00005502
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: Malpighian tubule tip cell primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic Malpighian tubule tip cell. It develops from some Malpighian tubule primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: Malpighian tubule tip cell primordium
annotated property: hasRelatedSynonym
annotated target: P1 MalTT
database_cross_reference: https://orcid.org/0000-0002-7073-9172

small intestine primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: hindgut proper primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic small intestine
definition: A(n) primordium that develops into some embryonic small intestine. It develops from some hindgut proper primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: P1 SmInt
has related synonym: small intestine specific anlage
id: FBbt:00005504
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: small intestine primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic small intestine. It develops from some hindgut proper primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: small intestine primordium
annotated property: hasRelatedSynonym
annotated target: P1 SmInt
database_cross_reference: https://orcid.org/0000-0002-7073-9172

large intestine primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: hindgut proper primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic large intestine
definition: A(n) primordium that develops into some embryonic large intestine. It develops from some hindgut proper primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: P1 LaInt
has related synonym: large intestine specific anlage
id: FBbt:00005505
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: large intestine primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic large intestine. It develops from some hindgut proper primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: large intestine primordium
annotated property: hasRelatedSynonym
annotated target: P1 LaInt
database_cross_reference: https://orcid.org/0000-0002-7073-9172

rectum primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: hindgut proper primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic/larval rectum
definition: A(n) primordium that develops into some embryonic/larval rectum. It develops from some hindgut proper primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: P1 Rect
has related synonym: rectum specific anlage
id: FBbt:00005506
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: rectum primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic/larval rectum. It develops from some hindgut proper primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: rectum primordium
annotated property: hasRelatedSynonym
annotated target: P1 Rect
database_cross_reference: https://orcid.org/0000-0002-7073-9172

mushroom body primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: central brain primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic central brain
subclass of: Restriction
  on property: develops into
  some values from: mushroom body
definition: Embryonic structure from which the mushroom body is derived. The development of the mushroom body proceeds as follows: axonogenesis of embryonic Kenyon cells starts late in embryonic stage 14. The axons from these cells extend towards the lateral protocerebral tract (LTP). During stage 16, a second set of Kenyon cell fibers form a second tract, closely apposed to the first. By late stage 16, both tracts extend anteriorly beyond the LTP to form the distal part of the peduncle. These tracts make a sharp medial turn close to the boundary with the deutocerebrum to form the medial lobe. By late stage 17 the vertical lobe has emerged as a collateral outgrowth from the point where these tracts bend. Finally, the calyx forms near to the end of embryogenesis.
has alternative id: FBbt:00005666
database_cross_reference: VFB:FBbt_00005508
has exact synonym: embryonic central brain mushroom body
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005508
in subset: cur

Axiom
annotated source: mushroom body primordium
annotated property: definition
annotated target: Embryonic structure from which the mushroom body is derived. The development of the mushroom body proceeds as follows: axonogenesis of embryonic Kenyon cells starts late in embryonic stage 14. The axons from these cells extend towards the lateral protocerebral tract (LTP). During stage 16, a second set of Kenyon cell fibers form a second tract, closely apposed to the first. By late stage 16, both tracts extend anteriorly beyond the LTP to form the distal part of the peduncle. These tracts make a sharp medial turn close to the boundary with the deutocerebrum to form the medial lobe. By late stage 17 the vertical lobe has emerged as a collateral outgrowth from the point where these tracts bend. Finally, the calyx forms near to the end of embryogenesis.
database_cross_reference: FlyBase:FBrf0144836

embryonic primordium of adult hindgut precursor
type: Class
subclass of: embryonic imaginal tissue
subclass of: primordium
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: hindgut proper primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic precursor of adult hindgut
definition: Primordium of the late extended germ band embryo that will give rise to the embryonic precursor of the adult hindgut.
has exact synonym: adult hindgut precursor primordium
has exact synonym: adult hindgut primordium
has OBO namespace: fly_anatomy.ontology
has related synonym: P1 AdHi
has related synonym: adult hindgut specific anlage
id: FBbt:00005513
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic primordium of adult hindgut precursor
annotated property: definition
annotated target: Primordium of the late extended germ band embryo that will give rise to the embryonic precursor of the adult hindgut.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

Axiom
annotated source: embryonic primordium of adult hindgut precursor
annotated property: hasRelatedSynonym
annotated target: P1 AdHi
database_cross_reference: https://orcid.org/0000-0002-7073-9172

early embryonic primordium of adult eye
type: Class
subclass of: FBbt_10005249
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00105515
definition: Early primordium of the late extended germ band and dorsal closure embryo that will give rise to the adult eye. It develops from the visual primordium.
has exact synonym: adult eye primordium early
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005515
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: early embryonic primordium of adult eye
annotated property: definition
annotated target: Early primordium of the late extended germ band and dorsal closure embryo that will give rise to the adult eye. It develops from the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic primordium of adult muscle precursor
type: Class
subclass of: embryonic imaginal tissue
subclass of: primordium
subclass of: FBbt_00026000
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops into
  some values from: embryonic precursor cell of adult muscle
definition: Primordium of the late extended germ band and dorsal closure embryo that will give rise to the embryonic precursor of the adult muscle.
has alternative id: FBbt:00005471
has exact synonym: adult muscle precursor primordium
has OBO namespace: fly_anatomy.ontology
has related synonym: adult muscle precursor specific anlage
id: FBbt:00005516
in subset: cur

Axiom
annotated source: embryonic primordium of adult muscle precursor
annotated property: definition
annotated target: Primordium of the late extended germ band and dorsal closure embryo that will give rise to the embryonic precursor of the adult muscle.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

somatic muscle primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: somatic trunk mesoderm derivative
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval muscle system
subclass of: Restriction
  on property: develops into
  some values from: FBbt_00058297
definition: Primordium of the larval segmentally-repeated body wall musculature. It arises from the outer layer of the trunk mesoderm. During germ band shortening (stage 13), it segregates into loose segmental clusters. Within these clusters, muscle formation proceeds by fusion of fusion competent myoblasts to muscle founder cells. Formation of the embryonic/larval somatic musculature is complete by stage 17.
has OBO namespace: fly_anatomy.ontology
has related synonym: P1 SoMus
has related synonym: SoMusP2
has related synonym: somatic muscle specific anlage
id: FBbt:00005518
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: somatic muscle primordium
annotated property: definition
annotated target: Primordium of the larval segmentally-repeated body wall musculature. It arises from the outer layer of the trunk mesoderm. During germ band shortening (stage 13), it segregates into loose segmental clusters. Within these clusters, muscle formation proceeds by fusion of fusion competent myoblasts to muscle founder cells. Formation of the embryonic/larval somatic musculature is complete by stage 17.
database_cross_reference: FlyBase:FBrf0064793
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: somatic muscle primordium
annotated property: hasRelatedSynonym
annotated target: P1 SoMus
database_cross_reference: https://orcid.org/0000-0002-7073-9172

fat body/gonad primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: somatic trunk mesoderm derivative
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: fat body primordium
  intersection of: Restriction
    on property: develops into
    some values from: gonadal sheath proper primordium
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
definition: Primordium which develops into the fat body and gonadal sheath. The cells that comprise it are specified from stage 10 (Jemc, 2010), though the first morphological sign of its development comes during stage 11, when the outer of the two layers of the trunk mesoderm thickens medially to become 2-3 cells thick. Segmentally arranged groups of cells split off from inner most layer of this thickening, becoming sandwiched between the somatic muscle primordium and the circular visceral muscle primordium. By stage 13, these segmental clusters have fused into continuous columns on either side of the embryo. These bands split into dorsal and ventral subdivisions. A sub-population of cells in the dorsal subdivision in parasegments 10-12 split off to form the gonadal sheath primordium during stage 14-15. The other cells then form the fat body primordium proper.
has exact synonym: bipotential lateral mesoderm
has narrow synonym: gonadal mesoderm
has OBO namespace: fly_anatomy.ontology
has related synonym: FaB/GP2
has related synonym: P2 FaB/GP
id: FBbt:00005520
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: fat body/gonad primordium
annotated property: definition
annotated target: Primordium which develops into the fat body and gonadal sheath. The cells that comprise it are specified from stage 10 (Jemc, 2010), though the first morphological sign of its development comes during stage 11, when the outer of the two layers of the trunk mesoderm thickens medially to become 2-3 cells thick. Segmentally arranged groups of cells split off from inner most layer of this thickening, becoming sandwiched between the somatic muscle primordium and the circular visceral muscle primordium. By stage 13, these segmental clusters have fused into continuous columns on either side of the embryo. These bands split into dorsal and ventral subdivisions. A sub-population of cells in the dorsal subdivision in parasegments 10-12 split off to form the gonadal sheath primordium during stage 14-15. The other cells then form the fat body primordium proper.
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0092473
database_cross_reference: FlyBase:FBrf0216740

Axiom
annotated source: fat body/gonad primordium
annotated property: hasExactSynonym
annotated target: bipotential lateral mesoderm
database_cross_reference: FlyBase:FBrf0102832

Axiom
annotated source: fat body/gonad primordium
annotated property: hasRelatedSynonym
annotated target: P2 FaB/GP
database_cross_reference: https://orcid.org/0000-0002-7073-9172

inclusive hindgut primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: hindgut proper primordium
  intersection of: Restriction
    on property: develops into
    some values from: Malpighian tubule primordium
subclass of: Restriction
  on property: part of
  some values from: posterior ectoderm
subclass of: Restriction
  on property: part of
  some values from: amnioproctodeal invagination
subclass of: Restriction
  on property: develops from
  some values from: hindgut anlage
definition: A(n) primordium that develops into some hindgut proper primordium and some Malpighian tubule primordium. It develops from some hindgut anlage.
has OBO namespace: fly_anatomy.ontology
has related synonym: iHiGP2
id: FBbt:00005523
in subset: cur

Axiom
annotated source: inclusive hindgut primordium
annotated property: definition
annotated target: A(n) primordium that develops into some hindgut proper primordium and some Malpighian tubule primordium. It develops from some hindgut anlage.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: inclusive hindgut primordium
annotated property: hasRelatedSynonym
annotated target: iHiGP2
database_cross_reference: https://orcid.org/0000-0002-7073-9172

dorsal epidermis primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: dorsal ectoderm derivative
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: embryonic leading edge cell primordium
  intersection of: Restriction
    on property: develops into
    some values from: dorsal sensory complex primordium
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00016019
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00016020
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00017020
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00017021
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
definition: A(n) primordium that develops into some dorsal apodeme anlage and some oenocyte primordium and some dorsal trunk epidermis primordium and some embryonic leading edge cell primordium and some dorsal sensory complex primordium and some abdominal histoblast anlage. It develops from some dorsal ectoderm.
database_cross_reference: UBERON:6005526
has OBO namespace: fly_anatomy.ontology
has related synonym: dorEpiP2
has related synonym: dorsal epidermis specific anlage
id: FBbt:00005526
in subset: cur

Axiom
annotated source: dorsal epidermis primordium
annotated property: definition
annotated target: A(n) primordium that develops into some dorsal apodeme anlage and some oenocyte primordium and some dorsal trunk epidermis primordium and some embryonic leading edge cell primordium and some dorsal sensory complex primordium and some abdominal histoblast anlage. It develops from some dorsal ectoderm.
database_cross_reference: FBC:Autogenerated

salivary gland duct primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic salivary gland
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
subclass of: Restriction
  on property: develops from
  some values from: salivary gland duct anlage
subclass of: Restriction
  on property: develops into
  some values from: embryonic/larval salivary gland duct
definition: A(n) primordium that develops into some embryonic/larval salivary gland duct. It develops from some salivary gland duct anlage.
has OBO namespace: fly_anatomy.ontology
has related synonym: P1 SalD
has related synonym: SalDP2
has related synonym: salivary gland duct specific anlage
id: FBbt:00005531
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: salivary gland duct primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic/larval salivary gland duct. It develops from some salivary gland duct anlage.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: salivary gland duct primordium
annotated property: hasRelatedSynonym
annotated target: P1 SalD
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral epidermis primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025993
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: imaginal disc primordium
  intersection of: Restriction
    on property: develops into
    some values from: embryonic ventral epidermis
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00016007
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00016008
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00016009
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_10005326
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
subclass of: Restriction
  on property: develops from
  some values from: ventral neurectoderm
definition: A(n) primordium that develops into some denticle field anlage and some anal pad primordium and some embryonic ventral epidermis and some imaginal disc primordium and some ventral apodeme anlage and some ventral trunk epidermis primordium. It develops from some ventral neurectoderm.
database_cross_reference: UBERON:6005533
has OBO namespace: fly_anatomy.ontology
has related synonym: P2 iVenEp
has related synonym: venEpiP2
id: FBbt:00005533
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral epidermis primordium
annotated property: definition
annotated target: A(n) primordium that develops into some denticle field anlage and some anal pad primordium and some embryonic ventral epidermis and some imaginal disc primordium and some ventral apodeme anlage and some ventral trunk epidermis primordium. It develops from some ventral neurectoderm.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: ventral epidermis primordium
annotated property: hasRelatedSynonym
annotated target: P2 iVenEp
database_cross_reference: https://orcid.org/0000-0002-7073-9172

gnathal primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: dorsal ectoderm derivative
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: maxillary sensory complex primordium
  intersection of: Restriction
    on property: develops into
    some values from: labial sensory complex primordium
  intersection of: Restriction
    on property: develops into
    some values from: larval foregut atrium
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00017019
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
definition: A(n) primordium that develops into some cibarium primordium and some labial sensory complex primordium and some maxillary sensory complex primordium and some larval foregut atrium. It develops from some dorsal ectoderm.
has OBO namespace: fly_anatomy.ontology
has related synonym: GnaP2
id: FBbt:00005534
in subset: cur

Axiom
annotated source: gnathal primordium
annotated property: definition
annotated target: A(n) primordium that develops into some cibarium primordium and some labial sensory complex primordium and some maxillary sensory complex primordium and some larval foregut atrium. It develops from some dorsal ectoderm.
database_cross_reference: FBC:Autogenerated

foregut primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: develops into
  some values from: foregut
definition: A(n) primordium that develops into some foregut.
has OBO namespace: fly_anatomy.ontology
has related synonym: FoGP2
id: FBbt:00005535
in subset: cur

Axiom
annotated source: foregut primordium
annotated property: definition
annotated target: A(n) primordium that develops into some foregut.
database_cross_reference: FBC:Autogenerated

cardiogenic mesoderm
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: trunk mesoderm
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
definition: Dorsal-most region of the trunk mesoderm that gives rise to the dorsal vessel (Campos-Ortega and Hartenstein, 1997). It forms a leading edge as the invaginated trunk mesoderm spreads from ventral to dorsal (Campos-Ortega and Hartenstein, 1997). The left and right regions eventually fuse at the dorsal midline and their cells differentiate into cardioblasts and pericardial cells (Campos-Ortega and Hartenstein, 1997).
has alternative id: FBbt:00005561
has exact synonym: CardMes
has exact synonym: CardMesP2
has exact synonym: P2 CardMes
has exact synonym: cardiac mesoderm
has exact synonym: mesodermal crest
has OBO namespace: fly_anatomy.ontology
has related synonym: cardiac mesoderm primordium
id: FBbt:00005541
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: cardiogenic mesoderm
annotated property: definition
annotated target: Dorsal-most region of the trunk mesoderm that gives rise to the dorsal vessel (Campos-Ortega and Hartenstein, 1997). It forms a leading edge as the invaginated trunk mesoderm spreads from ventral to dorsal (Campos-Ortega and Hartenstein, 1997). The left and right regions eventually fuse at the dorsal midline and their cells differentiate into cardioblasts and pericardial cells (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0253577

Axiom
annotated source: cardiogenic mesoderm
annotated property: hasExactSynonym
annotated target: P2 CardMes
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: cardiogenic mesoderm
annotated property: hasExactSynonym
annotated target: mesodermal crest
database_cross_reference: FlyBase:FBrf0089570

central brain primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00015256
subclass of: Restriction
  on property: develops into
  some values from: embryonic central brain
definition: Primordium of the embryonic central brain in the extended germ band and dorsal closure embryo.
has narrow synonym: P1 Cen Br
has narrow synonym: P3 CenBr
has OBO namespace: fly_anatomy.ontology
has related synonym: ProcEcP2
has related synonym: procephalic ectoderm primordium
id: FBbt:00005542
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: central brain primordium
annotated property: definition
annotated target: Primordium of the embryonic central brain in the extended germ band and dorsal closure embryo.
database_cross_reference: FBC:VH
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: central brain primordium
annotated property: hasNarrowSynonym
annotated target: P1 Cen Br
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: central brain primordium
annotated property: hasNarrowSynonym
annotated target: P3 CenBr
database_cross_reference: https://orcid.org/0000-0002-7073-9172

maxillary sensory complex primordium
type: Class
subclass of: developing embryonic structure
subclass of: sensory nervous system primordium
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: gnathal primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic maxillary sensory complex
definition: A(n) primordium that develops into some embryonic maxillary sensory complex. It develops from some gnathal primordium.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005544
in subset: cur

Axiom
annotated source: maxillary sensory complex primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic maxillary sensory complex. It develops from some gnathal primordium.
database_cross_reference: FBC:Autogenerated

labial sensory complex primordium
type: Class
subclass of: developing embryonic structure
subclass of: sensory nervous system primordium
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: gnathal primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic labial sensory complex
definition: A(n) primordium that develops into some embryonic labial sensory complex. It develops from some gnathal primordium.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005545
in subset: cur

Axiom
annotated source: labial sensory complex primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic labial sensory complex. It develops from some gnathal primordium.
database_cross_reference: FBC:Autogenerated

proventriculus primordium
type: Class
subclass of: primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic proventriculus
definition: A(n) primordium that develops into some embryonic proventriculus.
has OBO namespace: fly_anatomy.ontology
has related synonym: PvP3
id: FBbt:00005550
in subset: cur

Axiom
annotated source: proventriculus primordium
annotated property: definition
annotated target: A(n) primordium that develops into some embryonic proventriculus.
database_cross_reference: FBC:Autogenerated

sensory nervous system primordium
type: Class
subclass of: primordium
has OBO namespace: fly_anatomy.ontology
has related synonym: sensory nervous system specific anlage
id: FBbt:00005551
in subset: cur

dorsal sensory complex primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: dorsal ectoderm derivative
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: peripheral nervous system precursor cluster
  intersection of: Restriction
    on property: develops into
    some values from: prothoracic gland primordium
  intersection of: Restriction
    on property: develops into
    some values from: FBbt_00016023
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: dorsal epidermis primordium
definition: A(n) primordium that develops into some dorsal sensory complex proper primordium and some peripheral nervous system precursor cluster and some prothoracic gland primordium. It develops from some dorsal epidermis primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: A/P4 DorSens
id: FBbt:00005553
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: dorsal sensory complex primordium
annotated property: definition
annotated target: A(n) primordium that develops into some dorsal sensory complex proper primordium and some peripheral nervous system precursor cluster and some prothoracic gland primordium. It develops from some dorsal epidermis primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: dorsal sensory complex primordium
annotated property: hasRelatedSynonym
annotated target: A/P4 DorSens
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral nerve cord primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: portion of tissue
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral neurectoderm
subclass of: Restriction
  on property: develops into
  some values from: larval ventral nerve cord
definition: Primordium which is formed by the delamination of neuroblasts from the ventral neurogenic region. The first of five waves of delamination starts towards the end of embryonic stage 8. During stage 11, the mesectoderm loses contact with the outer surface and forms neuronal and glial precursors in the midline of this primordium.
has alternative id: FBbt:00000115
has alternative id: FBbt:00005430
has OBO namespace: fly_anatomy.ontology
has related synonym: AvenNeur
has related synonym: P3 venNeur
has related synonym: venNeurP3
has related synonym: ventral neurectoderm
has related synonym: ventral neuroderm primordium
has related synonym: ventral neuroectoderm
id: FBbt:00005554
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral nerve cord primordium
annotated property: definition
annotated target: Primordium which is formed by the delamination of neuroblasts from the ventral neurogenic region. The first of five waves of delamination starts towards the end of embryonic stage 8. During stage 11, the mesectoderm loses contact with the outer surface and forms neuronal and glial precursors in the midline of this primordium.
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: ventral nerve cord primordium
annotated property: hasRelatedSynonym
annotated target: P3 venNeur
database_cross_reference: https://orcid.org/0000-0002-7073-9172

repressed genital primordium
type: Class
subclass of: primordium
definition: Primordium of the genital disc associated with the development of structures of the opposite sex (Epper and Nothiger, 1982). It is largely, but not completely, repressed from developing into adult structures (Epper and Nothiger, 1982; Keisman et al., 2001).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005555
in subset: cur

Axiom
annotated source: repressed genital primordium
annotated property: definition
annotated target: Primordium of the genital disc associated with the development of structures of the opposite sex (Epper and Nothiger, 1982). It is largely, but not completely, repressed from developing into adult structures (Epper and Nothiger, 1982; Keisman et al., 2001).
database_cross_reference: FlyBase:FBrf0037847
database_cross_reference: FlyBase:FBrf0064788
database_cross_reference: FlyBase:FBrf0141451
database_cross_reference: FlyBase:FBrf0155710

ventral ectoderm
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: trunk ectoderm
subclass of: Restriction
  on property: develops from
  some values from: ventral ectoderm anlage
definition: Ventral region of the trunk ectoderm, which gives rise to the ventral epidermis and the central nervous system (Stathopoulos and Newcomb, 2020).
database_cross_reference: UBERON:6005558
has exact synonym: neuroectoderm
has exact synonym: neurogenic ectoderm
has OBO namespace: fly_anatomy.ontology
has related synonym: P2 VenEc
has related synonym: venEc
id: FBbt:00005558
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral ectoderm
annotated property: definition
annotated target: Ventral region of the trunk ectoderm, which gives rise to the ventral epidermis and the central nervous system (Stathopoulos and Newcomb, 2020).
database_cross_reference: FlyBase:FBrf0244630
database_cross_reference: FlyBase:FBrf0246683

Axiom
annotated source: ventral ectoderm
annotated property: hasExactSynonym
annotated target: neuroectoderm
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: ventral ectoderm
annotated property: hasExactSynonym
annotated target: neurogenic ectoderm
database_cross_reference: FlyBase:FBrf0246683

Axiom
annotated source: ventral ectoderm
annotated property: hasRelatedSynonym
annotated target: P2 VenEc
database_cross_reference: https://orcid.org/0000-0002-7073-9172

posterior endoderm
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: endoderm
subclass of: Restriction
  on property: part of
  some values from: stage 7 embryo
subclass of: Restriction
  on property: part of
  some values from: stage 8 embryo
subclass of: Restriction
  on property: part of
  some values from: FBbt_00014201
subclass of: Restriction
  on property: develops from
  some values from: posterior endoderm anlage
definition: The posterior part of the endoderm from its invagination as part of the amnioproctodeal invagination during stage 7, until it becomes morphologically distinct from the hindgut primordium due to a epithelial-to-mesenchymal transition at the end of stage 10 (Reuter et al., 1993). This epithelial-to-mesenchymal transition is also the transition from posterior endoderm to posterior midgut primordium.
has alternative id: FBbt:00005522
has alternative id: FBbt:00005525
has exact synonym: PMG
has exact synonym: posterior midgut rudiment
has OBO namespace: fly_anatomy.ontology
has related synonym: P2 postEndo
has related synonym: postEndo
has related synonym: postEndoP2
has related synonym: postMGRudP2
has related synonym: posterior endoderm primordium P2
has related synonym: posterior midgut primordium rudiment
id: FBbt:00005560
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: posterior endoderm
annotated property: definition
annotated target: The posterior part of the endoderm from its invagination as part of the amnioproctodeal invagination during stage 7, until it becomes morphologically distinct from the hindgut primordium due to a epithelial-to-mesenchymal transition at the end of stage 10 (Reuter et al., 1993). This epithelial-to-mesenchymal transition is also the transition from posterior endoderm to posterior midgut primordium.
database_cross_reference: FlyBase:FBrf0068651
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: posterior endoderm
annotated property: hasExactSynonym
annotated target: PMG
database_cross_reference: FlyBase:FBrf0064803

Axiom
annotated source: posterior endoderm
annotated property: hasRelatedSynonym
annotated target: P2 postEndo
database_cross_reference: https://orcid.org/0000-0002-7073-9172

presumptive embryonic/larval tracheal system
type: Class
subclass of: presumptive embryonic/larval system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval tracheal system. This corresponds to the tracheal primordia and their component tracheal branch primordia along with primordia of the spiracles.
database_cross_reference: UBERON:6005569
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic tracheal system
id: FBbt:00005569
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: presumptive embryonic/larval tracheal system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval tracheal system. This corresponds to the tracheal primordia and their component tracheal branch primordia along with primordia of the spiracles.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: presumptive embryonic/larval tracheal system
annotated property: hasRelatedSynonym
annotated target: embryonic tracheal system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic foregut
type: Class
subclass of: foregut
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval digestive system
subclass of: Restriction
  on property: develops from
  some values from: foregut anlage
definition: Foregut of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005606
in subset: cur

Axiom
annotated source: embryonic foregut
annotated property: definition
annotated target: Foregut of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic proventriculus
type: Class
subclass of: proventriculus
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval digestive system
subclass of: Restriction
  on property: overlaps
  some values from: embryonic/larval midgut
subclass of: Restriction
  on property: overlaps
  some values from: embryonic foregut
subclass of: Restriction
  on property: develops from
  some values from: proventriculus primordium
definition: Proventriculus of the embryo. It contains three distinct cell layers: inner, intermediate and outer. At the anterior end, corresponding to the most anterior region of the midgut, imaginal cells are found at the level of the intermediate layer.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005607
in subset: EmbDevSlim
in subset: cur
comment: This structure is more correctly referred to as the 'cardia'. Strictly, proventriculus refers to a modification of the foregut, just anterior to the stomodeal valve, found in many insects. Drosophila has no such foregut modification (Miller, 1950). However, the term 'proventriculus' is the one most commonly used for this structure.

Axiom
annotated source: embryonic proventriculus
annotated property: definition
annotated target: Proventriculus of the embryo. It contains three distinct cell layers: inner, intermediate and outer. At the anterior end, corresponding to the most anterior region of the midgut, imaginal cells are found at the level of the intermediate layer.
database_cross_reference: FlyBase:FBrf0064792

embryonic proventriculus inner layer
type: Class
subclass of: portion of tissue
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: embryonic proventriculus
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00018008
definition: Inner layer of the proventriculus of the embryo. It corresponds to the invaginated esophagus.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005608
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic proventriculus inner layer
annotated property: definition
annotated target: Inner layer of the proventriculus of the embryo. It corresponds to the invaginated esophagus.
database_cross_reference: FlyBase:FBrf0064792

embryonic proventriculus intermediate layer
type: Class
subclass of: portion of tissue
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: embryonic proventriculus
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00018009
definition: Intermediate layer of the proventriculus of the embryo. It corresponds to the invaginated foregut with alveolar cells. It contains imaginal cells at the level of the intermediate layer at the anterior end of the proventriculus.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005609
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic proventriculus intermediate layer
annotated property: definition
annotated target: Intermediate layer of the proventriculus of the embryo. It corresponds to the invaginated foregut with alveolar cells. It contains imaginal cells at the level of the intermediate layer at the anterior end of the proventriculus.
database_cross_reference: FlyBase:FBrf0064792

embryonic precursor of adult foregut
type: Class
subclass of: somatic precursor cell
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: foregut imaginal ring
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00018010
definition: Imaginal cell, set aside during embryonic development, that will give rise to the adult posterior foregut. These cells are found in a ring at the anterior part of the proventriculus, the foregut imaginal ring.
has exact synonym: adult foregut precursor
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005611
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic precursor of adult foregut
annotated property: definition
annotated target: Imaginal cell, set aside during embryonic development, that will give rise to the adult posterior foregut. These cells are found in a ring at the anterior part of the proventriculus, the foregut imaginal ring.
database_cross_reference: FlyBase:FBrf0064792

larval foregut atrium
type: Class
subclass of: dorsal ectoderm derivative
subclass of: FBbt_00100315
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval foregut
subclass of: Restriction
  on property: develops from
  some values from: gnathal primordium
definition: Most anterior stretch of the embryonic/larval foregut. Its posterior boundary, where the pharynx starts is immediately posterior to the openings of the salivary gland ducts.
has OBO namespace: fly_anatomy.ontology
has related synonym: mouth cavity
id: FBbt:00005615
in subset: cur

Axiom
annotated source: larval foregut atrium
annotated property: definition
annotated target: Most anterior stretch of the embryonic/larval foregut. Its posterior boundary, where the pharynx starts is immediately posterior to the openings of the salivary gland ducts.
database_cross_reference: FlyBase:FBrf0089570

embryonic foregut sensory structure
type: Class
equivalent class: Class
  intersection of: FBbt_00007236
  intersection of: Restriction
    on property: part of
    some values from: embryonic foregut
subclass of: FBbt_00007236
subclass of: Restriction
  on property: part of
  some values from: embryonic foregut
definition: Any internal compound sense organ (FBbt:00007236) that is part of some embryonic foregut (FBbt:00005606).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005616
in subset: cur

Axiom
annotated source: embryonic foregut sensory structure
annotated property: definition
annotated target: Any internal compound sense organ (FBbt:00007236) that is part of some embryonic foregut (FBbt:00005606).
database_cross_reference: FBC:Autogenerated

embryonic maxillary sensory complex
type: Class
subclass of: sense organ
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic maxillary segment
subclass of: Restriction
  on property: develops from
  some values from: maxillary sensory complex primordium
definition: Sense organ of the embryonic maxillary segment that gives rise to the terminal organ of the larval head. It is posterior and ventral to the embryonic brain by stage 13 and migrates ventrally and anteriorly to establish its final position, ventral to the dorsal organ, by stage 17.
database_cross_reference: VFB:FBbt_00005618
has exact synonym: embryonic terminal organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005618
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic maxillary sensory complex
annotated property: definition
annotated target: Sense organ of the embryonic maxillary segment that gives rise to the terminal organ of the larval head. It is posterior and ventral to the embryonic brain by stage 13 and migrates ventrally and anteriorly to establish its final position, ventral to the dorsal organ, by stage 17.
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: embryonic maxillary sensory complex
annotated property: hasExactSynonym
annotated target: embryonic terminal organ
database_cross_reference: FlyBase:FBrf0089570

embryonic labial sensory complex
type: Class
subclass of: dorsal ectoderm derivative
subclass of: FBbt_00007316
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: labial sensory complex primordium
definition: Developing labial sensory organ that has not yet reached its mature larval state. It starts to become distinct, and the developing neurons form nerves, during stage 13 (Campos-Ortega and Hartenstein, 1997). As foregut structures move inwards, it becomes incorporated into the ventral part of atrium around stage 15 (Campos-Ortega and Hartenstein, 1997).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005619
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic labial sensory complex
annotated property: definition
annotated target: Developing labial sensory organ that has not yet reached its mature larval state. It starts to become distinct, and the developing neurons form nerves, during stage 13 (Campos-Ortega and Hartenstein, 1997). As foregut structures move inwards, it becomes incorporated into the ventral part of atrium around stage 15 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

presumptive embryonic salivary gland
type: Class
subclass of: FBbt_00007276
subclass of: Restriction
  on property: part of
  some values from: embryonic foregut
definition: The sum of the primordia in the embryo that will contribute to the embryonic/larval salivary gland.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005620
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: presumptive embryonic salivary gland
annotated property: definition
annotated target: The sum of the primordia in the embryo that will contribute to the embryonic/larval salivary gland.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval midgut primordium
type: Class
subclass of: developing embryonic structure
subclass of: midgut primordium
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval digestive system
definition: A primordium that is a progenitor of all or part of the embryonic/larval midgut.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic midgut
id: FBbt:00005624
in subset: cur

Axiom
annotated source: embryonic/larval midgut primordium
annotated property: definition
annotated target: A primordium that is a progenitor of all or part of the embryonic/larval midgut.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic hindgut
type: Class
subclass of: hindgut
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval digestive system
definition: Posterior region of the embryonic gut, posterior to the embryonic midgut. It is divided into 3 domains: small and large intestine and rectum. Border cells separate these three regions.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005630
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic hindgut
annotated property: definition
annotated target: Posterior region of the embryonic gut, posterior to the embryonic midgut. It is divided into 3 domains: small and large intestine and rectum. Border cells separate these three regions.
database_cross_reference: FlyBase:FBrf0134749

embryonic small intestine
type: Class
subclass of: FBbt_00025992
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: embryonic hindgut
subclass of: Restriction
  on property: develops from
  some values from: small intestine primordium
definition: Anterior and small domain of the embryonic hindgut, posterior to the midgut.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005631
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic small intestine
annotated property: definition
annotated target: Anterior and small domain of the embryonic hindgut, posterior to the midgut.
database_cross_reference: FlyBase:FBrf0134749

embryonic large intestine
type: Class
subclass of: FBbt_00025992
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: embryonic hindgut
subclass of: Restriction
  on property: develops from
  some values from: large intestine primordium
definition: Middle and long domain of the embryonic hindgut, posterior to the small intestine.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005632
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic large intestine
annotated property: definition
annotated target: Middle and long domain of the embryonic hindgut, posterior to the small intestine.
database_cross_reference: FlyBase:FBrf0134749

embryonic Malpighian tubule
type: Class
subclass of: Malpighian tubule
subclass of: Restriction
  on property: continuous with
  some values from: embryonic hindgut
definition: Malpighian tubule of the embryo. By mid-embryogenesis when cell division ceases, a phase of tubule elongation starts, and the number of cells surrounding the lumen decreases from 6 to 10 to only 2.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005634
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic Malpighian tubule
annotated property: definition
annotated target: Malpighian tubule of the embryo. By mid-embryogenesis when cell division ceases, a phase of tubule elongation starts, and the number of cells surrounding the lumen decreases from 6 to 10 to only 2.
database_cross_reference: FlyBase:FBrf0064792

embryonic posterior Malpighian tubule
type: Class
subclass of: embryonic Malpighian tubule
subclass of: posterior Malpighian tubule
subclass of: FBbt_00025992
subclass of: Restriction
  on property: develops from
  some values from: Malpighian tubule main body primordium
definition: Posterior Malpighian tubule of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005635
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic posterior Malpighian tubule
annotated property: definition
annotated target: Posterior Malpighian tubule of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic Malpighian tubule segment
type: Class
subclass of: Malpighian tubule segment
subclass of: Restriction
  on property: part of
  some values from: embryonic Malpighian tubule
definition: Malpighian tubule segment of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005637
in subset: cur

Axiom
annotated source: embryonic Malpighian tubule segment
annotated property: definition
annotated target: Malpighian tubule segment of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic initial segment of Malpighian tubule
type: Class
subclass of: embryonic Malpighian tubule segment
subclass of: initial segment of Malpighian tubule
definition: Distal segment of the embryonic Malpighian tubule.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005638
in subset: cur

Axiom
annotated source: embryonic initial segment of Malpighian tubule
annotated property: definition
annotated target: Distal segment of the embryonic Malpighian tubule.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic ureter
type: Class
subclass of: embryonic Malpighian tubule segment
subclass of: ureter
definition: Proximal segment connecting a pair of Malpighian tubules to the alimentary canal in the embryo. The ureter is surrounded by longitudinal and circular muscles.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005641
in subset: cur

Axiom
annotated source: embryonic ureter
annotated property: definition
annotated target: Proximal segment connecting a pair of Malpighian tubules to the alimentary canal in the embryo. The ureter is surrounded by longitudinal and circular muscles.
database_cross_reference: FlyBase:FBrf0030988

embryonic specialized Malpighian tubule cell
type: Class
subclass of: specialized Malpighian tubule cell
subclass of: Restriction
  on property: part of
  some values from: embryonic Malpighian tubule
definition: Specialized cell of the embryonic Malpighian tubules.
has exact synonym: embryonic specialised Malpighian tubule cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005642
in subset: cur

Axiom
annotated source: embryonic specialized Malpighian tubule cell
annotated property: definition
annotated target: Specialized cell of the embryonic Malpighian tubules.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic Malpighian tubule tip cell
type: Class
subclass of: embryonic specialized Malpighian tubule cell
subclass of: Malpighian tubule tip cell
subclass of: FBbt_00025992
subclass of: Restriction
  on property: develops from
  some values from: Malpighian tubule tip cell primordium
definition: Tip cell of the embryonic Malpighian tubule. It persists throughout tubule elongation during stages 13-16 and contacts a specific target by the end of the process (Weavers and Skaer, 2013). It adopts a specialized morphology with the cell body projecting from the tubule tip on the end of a microtubule-enriched stalk (Weavers and Skaer, 2013). It can extend filopodia and lamellipodia to explore its environment and remains free of basement membrane (Weavers and Skaer, 2013).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005643
in subset: cur

Axiom
annotated source: embryonic Malpighian tubule tip cell
annotated property: definition
annotated target: Tip cell of the embryonic Malpighian tubule. It persists throughout tubule elongation during stages 13-16 and contacts a specific target by the end of the process (Weavers and Skaer, 2013). It adopts a specialized morphology with the cell body projecting from the tubule tip on the end of a microtubule-enriched stalk (Weavers and Skaer, 2013). It can extend filopodia and lamellipodia to explore its environment and remains free of basement membrane (Weavers and Skaer, 2013).
database_cross_reference: FlyBase:FBrf0223292

embryonic precursor of adult hindgut
type: Class
subclass of: developing embryonic structure
subclass of: somatic precursor cell
subclass of: FBbt_00025992
subclass of: Restriction
  on property: part of
  some values from: embryonic hindgut
subclass of: Restriction
  on property: overlaps
  some values from: larval hindgut imaginal ring
subclass of: Restriction
  on property: overlaps
  some values from: anal imaginal ring
subclass of: Restriction
  on property: develops from
  some values from: embryonic primordium of adult hindgut precursor
definition: Imaginal cell, set aside during embryonic development, that will give rise to the adult hindgut. These cells are found in two rings of the hindgut; immediately posterior to the ureters of the Malpighian tubules, and at the anus. These two rings grow out and eventually unite.
has exact synonym: adult hindgut precursor
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005646
in subset: cur

Axiom
annotated source: embryonic precursor of adult hindgut
annotated property: definition
annotated target: Imaginal cell, set aside during embryonic development, that will give rise to the adult hindgut. These cells are found in two rings of the hindgut; immediately posterior to the ureters of the Malpighian tubules, and at the anus. These two rings grow out and eventually unite.
database_cross_reference: FlyBase:FBrf0064792

presumptive embryonic/larval muscle system
type: Class
subclass of: presumptive embryonic/larval system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval muscle system.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic muscle system
id: FBbt:00005647
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: presumptive embryonic/larval muscle system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval muscle system.
database_cross_reference: FlyBase:FBrf0031016
database_cross_reference: FlyBase:FBrf0041814
database_cross_reference: FlyBase:FBrf0044229
database_cross_reference: FlyBase:FBrf0064793

Axiom
annotated source: presumptive embryonic/larval muscle system
annotated property: hasRelatedSynonym
annotated target: embryonic muscle system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic somatic muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00059033
subclass of: somatic muscle cell
subclass of: Restriction
  on property: part of
  some values from: FBbt_00059033
subclass of: Restriction
  on property: develops from
  some values from: myoblast
definition: Any muscle cell (FBbt:00005074) that is part of some embryonic somatic muscle (FBbt:00059033).
has exact synonym: embryonic skeletal muscle cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005649
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic somatic muscle cell
annotated property: definition
annotated target: Any muscle cell (FBbt:00005074) that is part of some embryonic somatic muscle (FBbt:00059033).
database_cross_reference: FBC:Autogenerated

embryonic central brain
type: Class
subclass of: FBbt_00025991
subclass of: FBbt_00047888
subclass of: Restriction
  on property: part of
  some values from: embryonic brain
subclass of: Restriction
  on property: develops from
  some values from: central brain primordium
definition: Brain of the embryo that excludes the optic lobes. It includes the protocerebrum, deutocerebrum and tritocerebrum.
database_cross_reference: VFB:FBbt_00005662
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005662
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic central brain
annotated property: definition
annotated target: Brain of the embryo that excludes the optic lobes. It includes the protocerebrum, deutocerebrum and tritocerebrum.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic central brain glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: embryonic central brain
subclass of: CNS glial cell
subclass of: FBbt_00052369
subclass of: Restriction
  on property: part of
  some values from: embryonic central brain
definition: Glial cell of the embryonic central brain.
database_cross_reference: VFB:FBbt_00005663
has exact synonym: embryonic central brain glia
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005663
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic central brain glial cell
annotated property: definition
annotated target: Glial cell of the embryonic central brain.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic central brain neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: embryonic central brain
subclass of: supraesophageal ganglion neuron
subclass of: Restriction
  on property: has soma location
  some values from: embryonic central brain
definition: Neuron of the embryonic central brain.
database_cross_reference: VFB:FBbt_00005665
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005665
in subset: cur

Axiom
annotated source: embryonic central brain neuron
annotated property: definition
annotated target: Neuron of the embryonic central brain.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

larval excretory system
type: Class
equivalent class: Class
  intersection of: excretory system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: excretory system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Excretory system of the late embryo or larva.
has exact synonym: embryonic/larval excretory system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005718
in subset: cur

Axiom
annotated source: larval excretory system
annotated property: definition
annotated target: Excretory system of the late embryo or larva.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

lamina anlage glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: lamina anlage
subclass of: CNS glial cell
subclass of: FBbt_00047861
subclass of: Restriction
  on property: part of
  some values from: lamina anlage
definition: Any glial cell (FBbt:00005144) that is part of some lamina anlage (FBbt:00001939).
database_cross_reference: VFB:FBbt_00005720
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005720
in subset: cur

Axiom
annotated source: lamina anlage glial cell
annotated property: definition
annotated target: Any glial cell (FBbt:00005144) that is part of some lamina anlage (FBbt:00001939).
database_cross_reference: FBC:Autogenerated

epithelial glial cell
type: Class
subclass of: neuropil glial cell
subclass of: Restriction
  on property: part of
  some values from: brain
definition: Cuboidal glial cell found in the visual system of larvae and adults, located more distal than the row of marginal glial cells. These glial cells contact marginal glia at their base (proximal) and satellite glia at their apex (distal), and constitute the only class of cells with nuclei in the neuropil proper, in the distal lamina.
database_cross_reference: VFB:FBbt_00005721
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005721
in subset: cur

Axiom
annotated source: epithelial glial cell
annotated property: definition
annotated target: Cuboidal glial cell found in the visual system of larvae and adults, located more distal than the row of marginal glial cells. These glial cells contact marginal glia at their base (proximal) and satellite glia at their apex (distal), and constitute the only class of cells with nuclei in the neuropil proper, in the distal lamina.
database_cross_reference: FlyBase:FBrf0055906
database_cross_reference: FlyBase:FBrf0134808
database_cross_reference: FlyBase:FBrf0214261

adult lamina marginal glial cell
type: Class
equivalent class: Class
  intersection of: FBbt_00047836
  intersection of: Restriction
    on property: part of
    some values from: lamina
subclass of: FBbt_00058224
subclass of: FBbt_00058264
subclass of: Restriction
  on property: part of
  some values from: optic cartridge
definition: Specialized ensheathing glial cell of the lamina (Edwards et al., 2012; Kremer et al., 2017). These cells form a contiguous layer at the proximal surface of the lamina and associate with multiple lamina columns (Edwards et al., 2012; Kremer et al., 2017). Their processes extend into the lamina, ensheathing proximal parts of the cartridges (Kremer et al., 2017). They also extend protrusions proximally into the outer chiasm (Kremer et al., 2017). It is between the marginal glial cells and epithelial glial cells that the R1-R6 growth cones terminate (Poeck et al., 2001; Winberg et al., 1992). There are around 100 of these cells per lamina (Kremer et al., 2017).
has alternative id: FBbt:00100515
database_cross_reference: VFB:FBbt_00005722
has exact synonym: L-EG
has exact synonym: adult lamina ensheathing glial cell
has OBO namespace: fly_anatomy.ontology
has related synonym: proximal glial cell
id: FBbt:00005722
in subset: cur

Axiom
annotated source: adult lamina marginal glial cell
annotated property: definition
annotated target: Specialized ensheathing glial cell of the lamina (Edwards et al., 2012; Kremer et al., 2017). These cells form a contiguous layer at the proximal surface of the lamina and associate with multiple lamina columns (Edwards et al., 2012; Kremer et al., 2017). Their processes extend into the lamina, ensheathing proximal parts of the cartridges (Kremer et al., 2017). They also extend protrusions proximally into the outer chiasm (Kremer et al., 2017). It is between the marginal glial cells and epithelial glial cells that the R1-R6 growth cones terminate (Poeck et al., 2001; Winberg et al., 1992). There are around 100 of these cells per lamina (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0055906
database_cross_reference: FlyBase:FBrf0134808
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0218414
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina marginal glial cell
annotated property: hasExactSynonym
annotated target: L-EG
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina marginal glial cell
annotated property: hasExactSynonym
annotated target: adult lamina ensheathing glial cell
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina marginal glial cell
annotated property: hasRelatedSynonym
annotated target: proximal glial cell
database_cross_reference: FlyBase:FBrf0134808

adult lamina satellite glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00100206
subclass of: FBbt_00058223
subclass of: Restriction
  on property: part of
  some values from: FBbt_00100206
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00100509
definition: Cell body glial cell of the lamina. Unlike in other cell body rind regions of the brain, the cell body glia of the lamina form two distinct layers and multiple neuronal cell bodies may be found in one glial pocket (Kremer et al., 2017).
has alternative id: FBbt:00100508
database_cross_reference: VFB:FBbt_00005723
has exact synonym: lamina cortex glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005723
in subset: cur

Axiom
annotated source: adult lamina satellite glial cell
annotated property: definition
annotated target: Cell body glial cell of the lamina. Unlike in other cell body rind regions of the brain, the cell body glia of the lamina form two distinct layers and multiple neuronal cell bodies may be found in one glial pocket (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0210316
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina satellite glial cell
annotated property: hasExactSynonym
annotated target: lamina cortex glial cell
database_cross_reference: FlyBase:FBrf0234767

adult excretory system
type: Class
equivalent class: Class
  intersection of: excretory system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: excretory system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Any excretory system of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005724
in subset: cur

Axiom
annotated source: adult excretory system
annotated property: definition
annotated target: Any excretory system of the adult.
database_cross_reference: FBC:Autogenerated

adult Malpighian tubule
type: Class
subclass of: Malpighian tubule
subclass of: Restriction
  on property: part of
  some values from: adult excretory system
subclass of: Restriction
  on property: continuous with
  some values from: adult hindgut
definition: Malpighian tubule of the adult. It is very similar to that of the larva, except that the initial segment of the anterior tubule is much smaller in the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005725
in subset: cur

Axiom
annotated source: adult Malpighian tubule
annotated property: definition
annotated target: Malpighian tubule of the adult. It is very similar to that of the larva, except that the initial segment of the anterior tubule is much smaller in the adult.
database_cross_reference: FlyBase:FBrf0222532

adult Malpighian tubule segment
type: Class
equivalent class: Class
  intersection of: Malpighian tubule segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: Malpighian tubule segment
subclass of: Restriction
  on property: part of
  some values from: adult Malpighian tubule
definition: Malpighian tubule segment of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005728
in subset: cur

Axiom
annotated source: adult Malpighian tubule segment
annotated property: definition
annotated target: Malpighian tubule segment of the adult.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult initial segment of Malpighian tubule
type: Class
equivalent class: Class
  intersection of: initial segment of Malpighian tubule
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult Malpighian tubule segment
subclass of: initial segment of Malpighian tubule
subclass of: Restriction
  on property: part of
  some values from: FBbt_00049468
definition: Distal segment of the adult Malpighian tubule. The initial segment of the adult is smaller than in the larva.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005729
in subset: cur

Axiom
annotated source: adult initial segment of Malpighian tubule
annotated property: definition
annotated target: Distal segment of the adult Malpighian tubule. The initial segment of the adult is smaller than in the larva.
database_cross_reference: FlyBase:FBrf0222532
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult ureter
type: Class
equivalent class: Class
  intersection of: ureter
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult Malpighian tubule segment
subclass of: ureter
subclass of: Restriction
  on property: part of
  some values from: FBbt_00049469
definition: Proximal segment connecting a pair of Malpighian tubules to the alimentary canal in the adult. The ureter is surrounded by longitudinal and circular muscles.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005732
in subset: cur

Axiom
annotated source: adult ureter
annotated property: definition
annotated target: Proximal segment connecting a pair of Malpighian tubules to the alimentary canal in the adult. The ureter is surrounded by longitudinal and circular muscles.
database_cross_reference: FlyBase:FBrf0030988
database_cross_reference: FlyBase:FBrf0160493

adult specialized Malpighian tubule cell
type: Class
equivalent class: Class
  intersection of: specialized Malpighian tubule cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: specialized Malpighian tubule cell
subclass of: Restriction
  on property: part of
  some values from: adult Malpighian tubule
definition: Specialized cell of the adult Malpighian tubules.
has exact synonym: adult specialised Malpighian tubule cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005733
in subset: cur

Axiom
annotated source: adult specialized Malpighian tubule cell
annotated property: definition
annotated target: Specialized cell of the adult Malpighian tubules.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult Malpighian tubule tip cell
type: Class
equivalent class: Class
  intersection of: Malpighian tubule tip cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult specialized Malpighian tubule cell
subclass of: Malpighian tubule tip cell
definition: Tip cell of the adult Malpighian tubule. The tip cell of the adult anterior tubules makes contact with alary muscles of the heart, whereas the tip cell of the posterior tubules contacts the a9 hindgut visceral nerve on the surface of the hindgut.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005734
in subset: cur

Axiom
annotated source: adult Malpighian tubule tip cell
annotated property: definition
annotated target: Tip cell of the adult Malpighian tubule. The tip cell of the adult anterior tubules makes contact with alary muscles of the heart, whereas the tip cell of the posterior tubules contacts the a9 hindgut visceral nerve on the surface of the hindgut.
database_cross_reference: FlyBase:FBrf0222532
database_cross_reference: FlyBase:FBrf0223292

adult Malpighian tubule principal cell
type: Class
equivalent class: Class
  intersection of: Malpighian tubule Type I cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult specialized Malpighian tubule cell
subclass of: Malpighian tubule Type I cell
subclass of: Restriction
  on property: expresses
  some values from: FBgn0004198
definition: Type I (principal) cell of the adult Malpighian tubule. These are found throughout the tubule and outnumber other cell types overall (Singh et al., 2007). They transport cations and organic solutes (Singh et al., 2007).
has exact synonym: adult Malpighian tubule Type I cell
has exact synonym: adult Malpighian tubule primary cell
has exact synonym: adult PC
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005735
in subset: cur
comment: It can be distinguished from other tubule cells by its high expression of cut, but stem cells also express a low level of cut (Wang and Spradling, 2020).

Axiom
annotated source: adult Malpighian tubule principal cell
annotated property: definition
annotated target: Type I (principal) cell of the adult Malpighian tubule. These are found throughout the tubule and outnumber other cell types overall (Singh et al., 2007). They transport cations and organic solutes (Singh et al., 2007).
database_cross_reference: FlyBase:FBrf0202697
database_cross_reference: FlyBase:FBrf0245230

Axiom
annotated source: adult Malpighian tubule principal cell
annotated property: hasExactSynonym
annotated target: adult Malpighian tubule Type I cell
database_cross_reference: FlyBase:FBrf0202697

Axiom
annotated source: adult Malpighian tubule principal cell
annotated property: hasExactSynonym
annotated target: adult Malpighian tubule primary cell
database_cross_reference: FlyBase:FBrf0202697

Axiom
annotated source: adult Malpighian tubule principal cell
annotated property: hasExactSynonym
annotated target: adult PC
database_cross_reference: FlyBase:FBrf0245230

adult medulla neuropil associated glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: medulla
subclass of: FBbt_00100517
subclass of: Restriction
  on property: part of
  some values from: medulla
definition: Glial cell located in the medulla neuropil. There are at least three subtypes of reticular glia and at least two subtypes of ensheathing glia (Kremer et al., 2017).
database_cross_reference: VFB:FBbt_00005738
has OBO namespace: fly_anatomy.ontology
has related synonym: MNG
id: FBbt:00005738

Axiom
annotated source: adult medulla neuropil associated glial cell
annotated property: definition
annotated target: Glial cell located in the medulla neuropil. There are at least three subtypes of reticular glia and at least two subtypes of ensheathing glia (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0096428
database_cross_reference: FlyBase:FBrf0134808
database_cross_reference: FlyBase:FBrf0210316
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult medulla neuropil associated glial cell
annotated property: hasRelatedSynonym
annotated target: MNG
database_cross_reference: FlyBase:FBrf0096428

embryonic dorsal epidermis
type: Class
subclass of: epidermis
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic epidermis
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00016019
definition: Epidermis of the dorsal region of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005744
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic dorsal epidermis
annotated property: definition
annotated target: Epidermis of the dorsal region of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic dorsal apodeme
type: Class
subclass of: apodeme
subclass of: dorsal ectoderm derivative
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00016021
definition: Dorsal halve of an embryonic apodeme. The discontinuity between dorsal and ventral halves is visible on a lateral view.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005745
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic dorsal apodeme
annotated property: definition
annotated target: Dorsal halve of an embryonic apodeme. The discontinuity between dorsal and ventral halves is visible on a lateral view.
database_cross_reference: FlyBase:FBrf0089570

embryonic ventral epidermis
type: Class
subclass of: FBbt_00025993
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: embryonic epidermis
subclass of: Restriction
  on property: develops from
  some values from: ventral epidermis primordium
definition: Epidermis of the ventral region of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005747
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic ventral epidermis
annotated property: definition
annotated target: Epidermis of the ventral region of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic anal pad
type: Class
subclass of: anal pad
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: embryonic ventral epidermis
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00016008
definition: Anal pad of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005748
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic anal pad
annotated property: definition
annotated target: Anal pad of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic ventral apodeme
type: Class
subclass of: apodeme
subclass of: FBbt_00025993
subclass of: Restriction
  on property: part of
  some values from: embryonic ventral epidermis
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00016010
definition: Ventral halve of an embryonic apodeme. The discontinuity between dorsal and ventral halves is visible on a lateral view.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005749
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic ventral apodeme
annotated property: definition
annotated target: Ventral halve of an embryonic apodeme. The discontinuity between dorsal and ventral halves is visible on a lateral view.
database_cross_reference: FlyBase:FBrf0089570

proventriculus
type: Class
subclass of: multi-tissue structure
subclass of: FBbt_00100315
subclass of: Restriction
  on property: overlaps
  some values from: foregut
subclass of: Restriction
  on property: overlaps
  some values from: midgut
definition: Bulb-shaped organ at the junction of the foregut and midgut that regulates the passage of food into the midgut. The proventriculus folds back on itself to produce three epithelial layers: internally the posterior region of the esophagus, an intermediate (recurrent) layer, derived from the ectodermal foregut and the midgut, and an external anterior projection of the endodermal midgut, which grows over the esophageal region. The inner two layers form the gastric valve (cardial valve) while the outer layer is defined as the wall of the proventriculus. The cuticle that lines the inner wall is thicker than other regions in the cardia, and it forms several longitudinal folds, causing the esophageal lumen to appear irregular in cross section. Between the intermediate and outer wall is the cardia lumen, which opens posteriorly into the lumen of the midgut. The anterior region secretes the peritrophic membrane into the cardia lumen. The epithelium is surrounded by a thin tunic of striated muscle fibers.
has exact synonym: cardia
has narrow synonym: cardiac valve
has narrow synonym: gastric valve
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005752
in subset: cur
comment: This structure is more correctly referred to as the 'cardia'. Strictly, proventriculus refers to a modification of the foregut, just anterior to the stomodeal valve, found in many insects. Drosophila has no such foregut modification (Miller, 1950). However, the term 'proventriculus' is the one most commonly used for this structure.

Axiom
annotated source: proventriculus
annotated property: definition
annotated target: Bulb-shaped organ at the junction of the foregut and midgut that regulates the passage of food into the midgut. The proventriculus folds back on itself to produce three epithelial layers: internally the posterior region of the esophagus, an intermediate (recurrent) layer, derived from the ectodermal foregut and the midgut, and an external anterior projection of the endodermal midgut, which grows over the esophageal region. The inner two layers form the gastric valve (cardial valve) while the outer layer is defined as the wall of the proventriculus. The cuticle that lines the inner wall is thicker than other regions in the cardia, and it forms several longitudinal folds, causing the esophageal lumen to appear irregular in cross section. Between the intermediate and outer wall is the cardia lumen, which opens posteriorly into the lumen of the midgut. The anterior region secretes the peritrophic membrane into the cardia lumen. The epithelium is surrounded by a thin tunic of striated muscle fibers.
database_cross_reference: FlyBase:FBrf0007732
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0048518
database_cross_reference: FlyBase:FBrf0064792

Axiom
annotated source: proventriculus
annotated property: hasExactSynonym
annotated target: cardia
database_cross_reference: FlyBase:FBrf0007735

Axiom
annotated source: proventriculus
annotated property: hasNarrowSynonym
annotated target: cardiac valve
database_cross_reference: FlyBase:FBrf0064792

Axiom
annotated source: proventriculus
annotated property: hasNarrowSynonym
annotated target: gastric valve
database_cross_reference: FlyBase:FBrf0064792

rectum
type: Class
subclass of: FBbt_00100315
subclass of: Restriction
  on property: part of
  some values from: hindgut
definition: Posterior-most portion of the alimentary canal, terminating in the anus.
database_cross_reference: UBERON:0006866
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005756
in subset: cur

Axiom
annotated source: rectum
annotated property: definition
annotated target: Posterior-most portion of the alimentary canal, terminating in the anus.
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0186027

neurohemal organ
type: Class
subclass of: FBbt_00007229
subclass of: FBbt_00007435
subclass of: FBbt_00100317
definition: Gland of the endocrine system from which neurosecretory substances are released into the hemolymph.
database_cross_reference: UBERON:0001053
has exact synonym: neurohaemal organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005757
in subset: cur

Axiom
annotated source: neurohemal organ
annotated property: definition
annotated target: Gland of the endocrine system from which neurosecretory substances are released into the hemolymph.
database_cross_reference: FlyBase:FBrf0239231

copper cell
type: Class
subclass of: BFO_0000040
subclass of: FBbt_00047177
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047108
subclass of: Restriction
  on property: capable of
  some values from: GO_0046717
subclass of: Restriction
  on property: expresses
  some values from: FBgn0002522
definition: Large cell in the middle region of the midgut that is cup-shaped with long microvilli. These cells accumulate copper and secrete acid.
has exact synonym: cuprophilic cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005782
in subset: cur
comment: These cells can be distinguished from other enterocytes by their strong expression of labial in the larval and adult gut (Dubreuil et al., 2001).

Axiom
annotated source: copper cell
annotated property: definition
annotated target: Large cell in the middle region of the midgut that is cup-shaped with long microvilli. These cells accumulate copper and secrete acid.
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0100557
database_cross_reference: FlyBase:FBrf0139611
database_cross_reference: FlyBase:FBrf0174753

Axiom
annotated source: copper cell
annotated property: hasExactSynonym
annotated target: cuprophilic cell
database_cross_reference: FlyBase:FBrf0139611

anal pad
type: Class
subclass of: FBbt_00100313
subclass of: Restriction
  on property: part of
  some values from: hindgut
definition: Plate or plates that surrounds the anus.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005785
in subset: cur

Axiom
annotated source: anal pad
annotated property: definition
annotated target: Plate or plates that surrounds the anus.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

Malpighian tubule
type: Class
subclass of: FBbt_00007474
subclass of: Restriction
  on property: part of
  some values from: excretory system
subclass of: Restriction
  on property: continuous with
  some values from: hindgut
definition: Epithelial tube with excretory and osmoregulatory roles connected, via a ureter, to the alimentary canal at the junction of the hindgut and midgut. At mid-embryogenesis, there are 6 to 10 cells encircling the lumen, whereas later on, after a phase of tubule elongation, only 2 cells encircle the lumen. There are two pairs of Malpighian tubules: one pair arises from the dorsal part of the hindgut and lies at the anterior end of the abdomen; the other pair arises from the ventral part of the hindgut and lies at the posterior end of the abdomen. Each pair shares a common ureter. The anterior pair is longer than the posterior pair.
database_cross_reference: UBERON:0001054
has exact synonym: renal tubule
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005786
in subset: FB gloss
in subset: cur

Axiom
annotated source: Malpighian tubule
annotated property: definition
annotated target: Epithelial tube with excretory and osmoregulatory roles connected, via a ureter, to the alimentary canal at the junction of the hindgut and midgut. At mid-embryogenesis, there are 6 to 10 cells encircling the lumen, whereas later on, after a phase of tubule elongation, only 2 cells encircle the lumen. There are two pairs of Malpighian tubules: one pair arises from the dorsal part of the hindgut and lies at the anterior end of the abdomen; the other pair arises from the ventral part of the hindgut and lies at the posterior end of the abdomen. Each pair shares a common ureter. The anterior pair is longer than the posterior pair.
database_cross_reference: FlyBase:FBrf0030988
database_cross_reference: FlyBase:FBrf0160493
database_cross_reference: FlyBase:FBrf0166419

Axiom
annotated source: Malpighian tubule
annotated property: hasExactSynonym
annotated target: renal tubule
database_cross_reference: FlyBase:FBrf0209268

posterior Malpighian tubule
type: Class
subclass of: Malpighian tubule
definition: Posterior Malpighian tubule that extends from the midgut hindgut border. It is formed from the ventral part of the hindgut. There is a pair of these that are connected to a common ureter that is on the midgut/hindgut border. The posterior tubules extend towards the tail of the embryo, with each tubule positioned on opposite sides within the body cavity. At the end of embryogenesis, the distal ends switch sides by crossing over the posterior region of the hindgut. In the mature tubules, the tip cell of the posterior tubules makes contact with the a9 abdominal visceral nerve. The posterior tubule pair is shorter than the posterior one.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005787
in subset: cur

Axiom
annotated source: posterior Malpighian tubule
annotated property: definition
annotated target: Posterior Malpighian tubule that extends from the midgut hindgut border. It is formed from the ventral part of the hindgut. There is a pair of these that are connected to a common ureter that is on the midgut/hindgut border. The posterior tubules extend towards the tail of the embryo, with each tubule positioned on opposite sides within the body cavity. At the end of embryogenesis, the distal ends switch sides by crossing over the posterior region of the hindgut. In the mature tubules, the tip cell of the posterior tubules makes contact with the a9 abdominal visceral nerve. The posterior tubule pair is shorter than the posterior one.
database_cross_reference: FlyBase:FBrf0075100
database_cross_reference: FlyBase:FBrf0222532

Malpighian tubule segment
type: Class
subclass of: FBbt_00007474
subclass of: Restriction
  on property: part of
  some values from: Malpighian tubule
definition: Segment of the Malpighian tubule. Each tubule can be divided into distinct segments based on differences in appearance, cell structure and function. The initial segment is involved in calcium homeostasis and excretion, the transitional and main segment are secretory and the lower tubule and ureter are reabsorptive. Type I cells are found in all segments, but Type II cells are only found in the upper tubule (initial, transitional and main segments).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005789
in subset: cur

Axiom
annotated source: Malpighian tubule segment
annotated property: definition
annotated target: Segment of the Malpighian tubule. Each tubule can be divided into distinct segments based on differences in appearance, cell structure and function. The initial segment is involved in calcium homeostasis and excretion, the transitional and main segment are secretory and the lower tubule and ureter are reabsorptive. Type I cells are found in all segments, but Type II cells are only found in the upper tubule (initial, transitional and main segments).
database_cross_reference: FlyBase:FBrf0030988
database_cross_reference: FlyBase:FBrf0083335
database_cross_reference: FlyBase:FBrf0128452
database_cross_reference: FlyBase:FBrf0184042
database_cross_reference: FlyBase:FBrf0202697
database_cross_reference: FlyBase:FBrf0218070
database_cross_reference: FlyBase:FBrf0222532
database_cross_reference: FlyBase:FBrf0245230

initial segment of Malpighian tubule
type: Class
subclass of: Malpighian tubule segment
definition: Distal segment of the Malpighian tubule. It is involved in calcium homeostasis and excretion. The initial segment of the adult is smaller than in the larva.
has exact synonym: distal segment of Malpighian tubule
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005790
in subset: cur

Axiom
annotated source: initial segment of Malpighian tubule
annotated property: definition
annotated target: Distal segment of the Malpighian tubule. It is involved in calcium homeostasis and excretion. The initial segment of the adult is smaller than in the larva.
database_cross_reference: FlyBase:FBrf0030988
database_cross_reference: FlyBase:FBrf0083335
database_cross_reference: FlyBase:FBrf0128452
database_cross_reference: FlyBase:FBrf0184042
database_cross_reference: FlyBase:FBrf0218070
database_cross_reference: FlyBase:FBrf0222532

Axiom
annotated source: initial segment of Malpighian tubule
annotated property: hasExactSynonym
annotated target: distal segment of Malpighian tubule
database_cross_reference: FlyBase:FBrf0083335

ureter
type: Class
subclass of: Malpighian tubule segment
definition: Proximal segment connecting a pair of Malpighian tubules to the alimentary canal. The ureter is surrounded by longitudinal and circular muscles.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005793
in subset: cur

Axiom
annotated source: ureter
annotated property: definition
annotated target: Proximal segment connecting a pair of Malpighian tubules to the alimentary canal. The ureter is surrounded by longitudinal and circular muscles.
database_cross_reference: FlyBase:FBrf0030988

specialized Malpighian tubule cell
type: Class
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: Malpighian tubule
definition: Specialized cell of the Malpighian tubules. There are four different types: type I, type II, tip and tiny cell.
has exact synonym: specialised Malpighian tubule cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005794
in subset: cur
in subset: scrnaseq slim
comment: Other cell types are known to exist, but have yet not been identified (personal communication by Helen Skaer).

Axiom
annotated source: specialized Malpighian tubule cell
annotated property: definition
annotated target: Specialized cell of the Malpighian tubules. There are four different types: type I, type II, tip and tiny cell.
database_cross_reference: FlyBase:FBrf0184042

Malpighian tubule tip cell
type: Class
subclass of: specialized Malpighian tubule cell
definition: Cell at the distal tip of each Malpighian tubule. It is involved in tube elongation in embryogenesis by stimulating cell proliferation in neighboring cells and in positioning the tubules.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005795
in subset: cur

Axiom
annotated source: Malpighian tubule tip cell
annotated property: definition
annotated target: Cell at the distal tip of each Malpighian tubule. It is involved in tube elongation in embryogenesis by stimulating cell proliferation in neighboring cells and in positioning the tubules.
database_cross_reference: FlyBase:FBrf0050653
database_cross_reference: FlyBase:FBrf0075100
database_cross_reference: FlyBase:FBrf0222532

Malpighian tubule Type I cell
type: Class
subclass of: specialized Malpighian tubule cell
definition: Morphologically distinct cell type found throughout the Malpighian tubules. It is a large epithelial cell joined by septate junctions to other Type I cells, with apical microvilli and infolding of the basal membrane. There are small differences between Type I cells in different tubule segments: in the initial segment, the cells have few microvilli and are relatively narrow compared with the larger, flatter cells of the main segment. Type I cells originate from division of the ectodermal Malpighian tubules primordial cells that are found in the junction between the hindgut and midgut. Type I cell proliferation is complete by late stage 13 of embryogenesis. In the mature tubules there are on average 484 Type I cells.
has exact synonym: Malpighian tubule principal cell
has exact synonym: PC
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005796
in subset: cur
comment: These cells are involved in primary urine production via the secretion of K+ into the lumen by a vacuolar-type H+ ATPase transporter and K+/H+ exchanger (Davies et al., 1996; Linton and O'Donnell, 1999).

Axiom
annotated source: Malpighian tubule Type I cell
annotated property: definition
annotated target: Morphologically distinct cell type found throughout the Malpighian tubules. It is a large epithelial cell joined by septate junctions to other Type I cells, with apical microvilli and infolding of the basal membrane. There are small differences between Type I cells in different tubule segments: in the initial segment, the cells have few microvilli and are relatively narrow compared with the larger, flatter cells of the main segment. Type I cells originate from division of the ectodermal Malpighian tubules primordial cells that are found in the junction between the hindgut and midgut. Type I cell proliferation is complete by late stage 13 of embryogenesis. In the mature tubules there are on average 484 Type I cells.
database_cross_reference: FlyBase:FBrf0064792
database_cross_reference: FlyBase:FBrf0091042
database_cross_reference: FlyBase:FBrf0108479
database_cross_reference: FlyBase:FBrf0160477

Axiom
annotated source: Malpighian tubule Type I cell
annotated property: hasExactSynonym
annotated target: Malpighian tubule principal cell
database_cross_reference: FlyBase:FBrf0030988

corpus cardiacum
type: Class
subclass of: neurohemal organ
subclass of: Restriction
  on property: part of
  some values from: retrocerebral complex
subclass of: Restriction
  on property: continuous with
  some values from: FBbt_00049645
definition: Neuroendocrine structure that forms part of the ring gland. In the embryo and larva it is found around the floor of the aorta, just anterior to the brain (Dai and Gilbert, 1991; de Velasco et al., 2004, Nassel and Zandawala, 2020). It migrates posteriorly during metamorphosis (Dai and Gilbert, 1991) and is found posterior to the brain, near the proventriculus, in the adult (Nassel and Zandawala, 2020). It produces Adipokinetic hormone from late embryo to adult stages (Lee and Park, 2004).
database_cross_reference: UBERON:0001056
has exact synonym: CC
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005799
in subset: cur

Axiom
annotated source: corpus cardiacum
annotated property: definition
annotated target: Neuroendocrine structure that forms part of the ring gland. In the embryo and larva it is found around the floor of the aorta, just anterior to the brain (Dai and Gilbert, 1991; de Velasco et al., 2004, Nassel and Zandawala, 2020). It migrates posteriorly during metamorphosis (Dai and Gilbert, 1991) and is found posterior to the brain, near the proventriculus, in the adult (Nassel and Zandawala, 2020). It produces Adipokinetic hormone from late embryo to adult stages (Lee and Park, 2004).
database_cross_reference: FlyBase:FBrf0053727
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0178933
database_cross_reference: FlyBase:FBrf0247015

Axiom
annotated source: corpus cardiacum
annotated property: hasExactSynonym
annotated target: CC
database_cross_reference: FlyBase:FBrf0247015

corpus allatum
type: Class
subclass of: neurohemal organ
subclass of: Restriction
  on property: part of
  some values from: retrocerebral complex
definition: Neuroendocrine structure that forms part of the ring gland. In the embryo and larva it is found dorsal the aorta, anterior to the brain (Dai and Gilbert, 1991; de Velasco et al., 2004, Nassel and Zandawala, 2020). It migrates posteriorly during metamorphosis (Dai and Gilbert, 1991) and in the adult it is found posterior to the brain, dorsal to the corpus cardiacum (Nassel and Zandawala, 2020). It produces juvenile hormone (Dai and Gilbert, 1991; Hartenstein, 1993; Nassel and Zandawala, 2020).
database_cross_reference: UBERON:0001057
has exact synonym: CA
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005800
in subset: cur

Axiom
annotated source: corpus allatum
annotated property: definition
annotated target: Neuroendocrine structure that forms part of the ring gland. In the embryo and larva it is found dorsal the aorta, anterior to the brain (Dai and Gilbert, 1991; de Velasco et al., 2004, Nassel and Zandawala, 2020). It migrates posteriorly during metamorphosis (Dai and Gilbert, 1991) and in the adult it is found posterior to the brain, dorsal to the corpus cardiacum (Nassel and Zandawala, 2020). It produces juvenile hormone (Dai and Gilbert, 1991; Hartenstein, 1993; Nassel and Zandawala, 2020).
database_cross_reference: FlyBase:FBrf0053727
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0179777
database_cross_reference: FlyBase:FBrf0247015

Axiom
annotated source: corpus allatum
annotated property: hasExactSynonym
annotated target: CA
database_cross_reference: FlyBase:FBrf0247015

mushroom body
type: Class
subclass of: BFO_0000040
subclass of: FBbt_00025991
subclass of: FBbt_00041000
subclass of: Restriction
  on property: part of
  some values from: protocerebrum
subclass of: Restriction
  on property: develops from
  some values from: mushroom body primordium
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0007613
definition: Bilaterally paired neuropil structure situated postero-dorsally in the protocerebrum that functions in olfactory associative learning and memory. The mushroom body is divided into: the calyx, which is closest to the cortex and receives sensory interneuron afferents; the pedunculus, which is a thick axon bundle extending from the calyx to the base of the lobes; and the mushroom body lobe system, which consists of a vertical branch and a medial branch, which have different structures at different life stages (Lee et al., 1999; Ito et al., 2014).
database_cross_reference: UBERON:0001058
database_cross_reference: VFB:FBbt_00005801
has exact synonym: MB
has exact synonym: corpora pedunculata
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005801
in subset: BrainName
in subset: FB gloss
in subset: cur
comment: This term as defined in Ito et al. (2014) corresponds to both the mushroom body (MB) and calyx (Cal) of Chiang et al. (2011).

Axiom
annotated source: mushroom body
annotated property: definition
annotated target: Bilaterally paired neuropil structure situated postero-dorsally in the protocerebrum that functions in olfactory associative learning and memory. The mushroom body is divided into: the calyx, which is closest to the cortex and receives sensory interneuron afferents; the pedunculus, which is a thick axon bundle extending from the calyx to the base of the lobes; and the mushroom body lobe system, which consists of a vertical branch and a medial branch, which have different structures at different life stages (Lee et al., 1999; Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0111409
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0248215

Axiom
annotated source: mushroom body
annotated property: hasExactSynonym
annotated target: MB
database_cross_reference: FlyBase:FBrf0219809

Bolwig organ
type: Class
subclass of: larval ocular segment sense organ
subclass of: photoreceptor
subclass of: FBbt_00007233
subclass of: FBbt_00007242
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: late embryo
subclass of: Restriction
  on property: develops from
  some values from: Bolwig organ primordium
subclass of: Restriction
  on property: capable of
  some values from: GO_0050908
definition: Visual organ of the larva that is anchored to the basal surface of the thin epithelium of the dorsal pouch, lateral to the musculature of the pharynx (Green et al., 1993; Hartenstein et al., 2019). It consists of a dense cluster of approximately 12 photoreceptor neurons and no support cells (Green et al., 1993; Hartenstein et al., 2019). It is connected to the brain via the Bolwig nerve (Green et al., 1993).
has alternative id: FBbt:00002643
has alternative id: FBbt:00005742
has alternative id: FBbt:00015250
database_cross_reference: UBERON:6005805
database_cross_reference: VFB:FBbt_00005805
has exact synonym: Bolwig's organ
has exact synonym: embryonic Bolwig's organ
has exact synonym: embryonic visual system
has exact synonym: larval Bolwig's organ
has exact synonym: larval eye
has exact synonym: stemmata organ
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsocaudal pharyngeal sense organ
id: FBbt:00005805
in subset: FB gloss
in subset: cur
comment: Location in ocular segment on basis of FBrf0075072.

Axiom
annotated source: Bolwig organ
annotated property: definition
annotated target: Visual organ of the larva that is anchored to the basal surface of the thin epithelium of the dorsal pouch, lateral to the musculature of the pharynx (Green et al., 1993; Hartenstein et al., 2019). It consists of a dense cluster of approximately 12 photoreceptor neurons and no support cells (Green et al., 1993; Hartenstein et al., 2019). It is connected to the brain via the Bolwig nerve (Green et al., 1993).
database_cross_reference: FlyBase:FBrf0064481
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0243080

Axiom
annotated source: Bolwig organ
annotated property: hasExactSynonym
annotated target: larval eye
database_cross_reference: FlyBase:FBrf0213587

Axiom
annotated source: Bolwig organ
annotated property: hasExactSynonym
annotated target: stemmata organ
database_cross_reference: FlyBase:FBrf0047902

antennal sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: antennal segment
definition: Any sense organ (FBbt:00005155) that is part of some antennal segment (FBbt:00000009).
has alternative id: FBbt:00004171
database_cross_reference: VFB:FBbt_00005806
has exact synonym: antennal sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005806
in subset: cur

Axiom
annotated source: antennal sense organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is part of some antennal segment (FBbt:00000009).
database_cross_reference: FBC:Autogenerated

first optic chiasma
type: Class
subclass of: optic chiasma
subclass of: Restriction
  on property: innervates
  some values from: lamina
subclass of: Restriction
  on property: innervates
  some values from: medulla
definition: Chiasma lying between the lamina and medulla of the optic lobe (Ito et al., 2014). Axons reverse the anterior-posterior order between the lamina and the medulla, with axons from the anterior lamina cartridges projecting to the posterior medulla columns (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00005810
has exact synonym: OCH1
has exact synonym: first optic chiasm
has exact synonym: outer optic chiasm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005810
in subset: cur

Axiom
annotated source: first optic chiasma
annotated property: definition
annotated target: Chiasma lying between the lamina and medulla of the optic lobe (Ito et al., 2014). Axons reverse the anterior-posterior order between the lamina and the medulla, with axons from the anterior lamina cartridges projecting to the posterior medulla columns (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: first optic chiasma
annotated property: hasExactSynonym
annotated target: OCH1
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

chiasma
type: Class
subclass of: tract
definition: A tract of crossing fibers, that remaps or systematically permutates the linear order between two neuropils.
has alternative id: FBbt:00005102
database_cross_reference: VFB:FBbt_00005814
has exact synonym: chiasm
has exact synonym: decussation
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005814
in subset: cur

Axiom
annotated source: chiasma
annotated property: definition
annotated target: A tract of crossing fibers, that remaps or systematically permutates the linear order between two neuropils.
database_cross_reference: FlyBase:FBrf0224194

embryonic outer optic lobe primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: FBbt_00025991
subclass of: Restriction
  on property: part of
  some values from: embryonic optic lobe primordium
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: larval outer optic anlage
definition: Primordium of the late extended germ band and closure embryo that gives rise to the larval outer optic anlage. It develops from the posterior lip of the visual primordium.
has exact synonym: P1 OOA
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005822
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic outer optic lobe primordium
annotated property: definition
annotated target: Primordium of the late extended germ band and closure embryo that gives rise to the larval outer optic anlage. It develops from the posterior lip of the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: embryonic outer optic lobe primordium
annotated property: hasExactSynonym
annotated target: P1 OOA
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Bolwig organ primordium
type: Class
subclass of: primordium
subclass of: FBbt_00025991
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: Bolwig organ
definition: Primordium of the embryo that gives rise to the larval Bolwig organ. It develops from the most posterior region of the visual primordium, remaining attached to the surface as the rest of the optic placode becomes internalized during stages 12-13 (Green et al., 1993). It consists of approximately 12 cells, which begin to differentiate into photoreceptors during stage 13 (Green et al., 1993). During stages 15-16, the photoreceptors move out of the epidermis and come to lie attached to the outer lining of the dorsal pouch (Green et al., 1993).
database_cross_reference: UBERON:6005830
has exact synonym: Bolwig's organ primordium
has exact synonym: P1 BolOrg
has exact synonym: larval eye primordium
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005830
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: Bolwig organ primordium
annotated property: definition
annotated target: Primordium of the embryo that gives rise to the larval Bolwig organ. It develops from the most posterior region of the visual primordium, remaining attached to the surface as the rest of the optic placode becomes internalized during stages 12-13 (Green et al., 1993). It consists of approximately 12 cells, which begin to differentiate into photoreceptors during stage 13 (Green et al., 1993). During stages 15-16, the photoreceptors move out of the epidermis and come to lie attached to the outer lining of the dorsal pouch (Green et al., 1993).
database_cross_reference: FlyBase:FBrf0064481
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: FlyBase:FBrf0243080

Axiom
annotated source: Bolwig organ primordium
annotated property: hasExactSynonym
annotated target: P1 BolOrg
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: Bolwig organ primordium
annotated property: hasExactSynonym
annotated target: larval eye primordium
database_cross_reference: FlyBase:FBrf0141490

dorsal imaginal tissue
type: Class
subclass of: FBbt_00047552
definition: Imaginal tissue that has a dorsal location.
database_cross_reference: UBERON:6005831
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsal imaginal precursor
id: FBbt:00005831
in subset: cur

adult peripheral nervous system
type: Class
equivalent class: Class
  intersection of: peripheral nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: peripheral nervous system
subclass of: Restriction
  on property: part of
  some values from: adult nervous system
definition: Peripheral nervous system of the adult.
database_cross_reference: VFB:FBbt_00005892
has exact synonym: adult PNS
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005892
in subset: cur

Axiom
annotated source: adult peripheral nervous system
annotated property: definition
annotated target: Peripheral nervous system of the adult.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

larval peripheral nervous system
type: Class
equivalent class: Class
  intersection of: peripheral nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: peripheral nervous system
subclass of: Restriction
  on property: part of
  some values from: larval nervous system
definition: Peripheral nervous system of the embryo or larva.
database_cross_reference: VFB:FBbt_00005893
has exact synonym: embryonic/larval PNS
has exact synonym: embryonic/larval peripheral nervous system
has exact synonym: larval PNS
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005893
in subset: cur
in subset: larval OF

Axiom
annotated source: larval peripheral nervous system
annotated property: definition
annotated target: Peripheral nervous system of the embryo or larva.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

intermediate longitudinal fascicle
type: Class
subclass of: larval longitudinal connective
definition: Longitudinal fascicle of the larval ventral nerve cord that is located in an intermediate position on the medial-lateral axis.
database_cross_reference: VFB:FBbt_00005903
has OBO namespace: fly_anatomy.ontology
has related synonym: central longitudinal fascicle
has related synonym: second Fas2 fascicle
id: FBbt:00005903
in subset: cur

Axiom
annotated source: intermediate longitudinal fascicle
annotated property: definition
annotated target: Longitudinal fascicle of the larval ventral nerve cord that is located in an intermediate position on the medial-lateral axis.
database_cross_reference: FlyBase:FBrf0076999
database_cross_reference: FlyBase:FBrf0105910
database_cross_reference: FlyBase:FBrf0156020
database_cross_reference: FlyBase:FBrf0160715

C1 fascicle
type: Class
subclass of: intermediate longitudinal fascicle
subclass of: Restriction
  on property: part of
  some values from: FBbt_00111638
definition: Dorsalmost fascicle that is part of the centrointermediate (CI) fascicle in the larval ventral nerve cord (Zlatic et al., 2003).
database_cross_reference: VFB:FBbt_00005905
database_cross_reference: larvalbrain_axon_tract:45
has exact synonym: C1 tract
has exact synonym: CI 1 fascicle
has exact synonym: CI1 tract
has exact synonym: CITd
has exact synonym: centro-intermediate tract dorsal
has exact synonym: centrointermediate 1 fascicle
has exact synonym: dorsal central intermediate tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005905
in subset: cur

Axiom
annotated source: C1 fascicle
annotated property: definition
annotated target: Dorsalmost fascicle that is part of the centrointermediate (CI) fascicle in the larval ventral nerve cord (Zlatic et al., 2003).
database_cross_reference: FlyBase:FBrf0156020
database_cross_reference: FlyBase:FBrf0160715

Axiom
annotated source: C1 fascicle
annotated property: hasExactSynonym
annotated target: CI 1 fascicle
database_cross_reference: FlyBase:FBrf0160715

Axiom
annotated source: C1 fascicle
annotated property: hasExactSynonym
annotated target: CI1 tract
database_cross_reference: FlyBase:FBrf0202785

Axiom
annotated source: C1 fascicle
annotated property: hasExactSynonym
annotated target: CITd
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: C1 fascicle
annotated property: hasExactSynonym
annotated target: centrointermediate 1 fascicle
database_cross_reference: FlyBase:FBrf0160715

Axiom
annotated source: C1 fascicle
annotated property: hasExactSynonym
annotated target: dorsal central intermediate tract
database_cross_reference: FlyBase:FBrf0237252

C2 fascicle
type: Class
subclass of: intermediate longitudinal fascicle
subclass of: Restriction
  on property: part of
  some values from: FBbt_00111638
definition: Second-most ventral fascicle that is part of the centrointermediate (CI) fascicle in the larval ventral nerve cord (Zlatic et al., 2003).
has broad synonym: CITv
has broad synonym: ventral central intermediate tract
database_cross_reference: VFB:FBbt_00005906
has exact synonym: C2 tract
has exact synonym: CI 2 fascicle
has exact synonym: CI2 tract
has exact synonym: centrointermediate 2 fascicle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005906
in subset: cur
comment: CITv encompasses 'C2 fascicle' and 'C3 fascicle' - FBC:DW.

Axiom
annotated source: C2 fascicle
annotated property: definition
annotated target: Second-most ventral fascicle that is part of the centrointermediate (CI) fascicle in the larval ventral nerve cord (Zlatic et al., 2003).
database_cross_reference: FlyBase:FBrf0156020
database_cross_reference: FlyBase:FBrf0160715

Axiom
annotated source: C2 fascicle
annotated property: hasBroadSynonym
annotated target: CITv
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: C2 fascicle
annotated property: hasBroadSynonym
annotated target: ventral central intermediate tract
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: C2 fascicle
annotated property: hasExactSynonym
annotated target: CI 2 fascicle
database_cross_reference: FlyBase:FBrf0160715

Axiom
annotated source: C2 fascicle
annotated property: hasExactSynonym
annotated target: CI2 tract
database_cross_reference: FlyBase:FBrf0202785

Axiom
annotated source: C2 fascicle
annotated property: hasExactSynonym
annotated target: centrointermediate 2 fascicle
database_cross_reference: FlyBase:FBrf0160715

C3 fascicle
type: Class
subclass of: intermediate longitudinal fascicle
subclass of: Restriction
  on property: part of
  some values from: FBbt_00111638
definition: Ventralmost fascicle that is part of the centrointermediate (CI) fascicle in the larval ventral nerve cord (Zlatic et al., 2003).
has broad synonym: CITv
has broad synonym: ventral central intermediate tract
database_cross_reference: VFB:FBbt_00005907
has exact synonym: C3 tract
has exact synonym: CI 3 fascicle
has exact synonym: CI3 tract
has exact synonym: centrointermediate 3 fascicle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005907
in subset: cur
comment: CITv encompasses 'C2 fascicle' and 'C3 fascicle' - FBC:DW.

Axiom
annotated source: C3 fascicle
annotated property: definition
annotated target: Ventralmost fascicle that is part of the centrointermediate (CI) fascicle in the larval ventral nerve cord (Zlatic et al., 2003).
database_cross_reference: FlyBase:FBrf0156020
database_cross_reference: FlyBase:FBrf0160715

Axiom
annotated source: C3 fascicle
annotated property: hasBroadSynonym
annotated target: CITv
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: C3 fascicle
annotated property: hasBroadSynonym
annotated target: ventral central intermediate tract
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: C3 fascicle
annotated property: hasExactSynonym
annotated target: CI 3 fascicle
database_cross_reference: FlyBase:FBrf0160715

Axiom
annotated source: C3 fascicle
annotated property: hasExactSynonym
annotated target: CI3 tract
database_cross_reference: FlyBase:FBrf0202785

Axiom
annotated source: C3 fascicle
annotated property: hasExactSynonym
annotated target: centrointermediate 3 fascicle
database_cross_reference: FlyBase:FBrf0160715

mechanosensory neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050974
subclass of: CL_0000199
subclass of: sensory neuron
subclass of: FBbt_00007698
definition: Any neuron (FBbt:00005106) that is capable of some detection of mechanical stimulus involved in sensory perception (GO:0050974).
database_cross_reference: VFB:FBbt_00005919
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005919
in subset: cur

Axiom
annotated source: mechanosensory neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some detection of mechanical stimulus involved in sensory perception (GO:0050974).
database_cross_reference: FBC:Autogenerated

chemosensory neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050907
subclass of: sensory neuron
subclass of: FBbt_00007696
subclass of: Restriction
  on property: capable of
  some values from: GO_0050907
definition: Any neuron (FBbt:00005106) that is capable of some detection of chemical stimulus involved in sensory perception (GO:0050907).
database_cross_reference: VFB:FBbt_00005922
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005922
in subset: cur
in subset: larval OF

Axiom
annotated source: chemosensory neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some detection of chemical stimulus involved in sensory perception (GO:0050907).
database_cross_reference: FBC:Autogenerated

olfactory receptor neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050911
subclass of: CL_0000207
subclass of: chemosensory neuron
subclass of: FBbt_00007697
subclass of: FBbt_00059272
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
definition: Any neuron (FBbt:00005106) that is capable of some detection of chemical stimulus involved in sensory perception of smell (GO:0050911).
database_cross_reference: VFB:FBbt_00005926
has exact synonym: ORN
has exact synonym: OSN
has exact synonym: odorant receptor neuron
has exact synonym: olfactory sensory neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005926
in subset: cur
in subset: hidden assertion

Axiom
annotated source: olfactory receptor neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some detection of chemical stimulus involved in sensory perception of smell (GO:0050911).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: olfactory receptor neuron
annotated property: hasExactSynonym
annotated target: OSN
database_cross_reference: FlyBase:FBrf0191451

Axiom
annotated source: olfactory receptor neuron
annotated property: hasExactSynonym
annotated target: olfactory sensory neuron
database_cross_reference: FlyBase:FBrf0191451

gustatory receptor neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050912
subclass of: chemosensory neuron
subclass of: FBbt_00007695
subclass of: Restriction
  on property: capable of
  some values from: GO_0050912
definition: Any neuron (FBbt:00005106) that is capable of some detection of chemical stimulus involved in sensory perception of taste (GO:0050912).
database_cross_reference: VFB:FBbt_00005927
has exact synonym: GRN
has exact synonym: GSN
has exact synonym: gustatory sensory neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005927
in subset: cur
in subset: hidden assertion

Axiom
annotated source: gustatory receptor neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some detection of chemical stimulus involved in sensory perception of taste (GO:0050912).
database_cross_reference: FlyBase:FBrf0179479
database_cross_reference: FlyBase:FBrf0208984

somatic trunk mesoderm derivative
type: Class
equivalent class: Class
  intersection of: FBbt_10000000
  intersection of: Restriction
    on property: develops from
    some values from: somatic trunk mesoderm
subclass of: FBbt_00026000
subclass of: Restriction
  on property: develops from
  some values from: somatic trunk mesoderm
definition: Any anatomical entity (FBbt:10000000) that develops from some somatic trunk mesoderm (FBbt:00000129).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006001
in subset: cur

Axiom
annotated source: somatic trunk mesoderm derivative
annotated property: definition
annotated target: Any anatomical entity (FBbt:10000000) that develops from some somatic trunk mesoderm (FBbt:00000129).
database_cross_reference: https://orcid.org/0000-0002-7073-9172

outer photoreceptor cell
type: Class
subclass of: eye photoreceptor cell
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: optic cartridge
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: optic cartridge
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina intrinsic neuron Lai
definition: An eye photoreceptor cell whose rhabdomere is part of the outer trapezoid of rhabdomeres of each ommatidium. There are six of these per ommatidium. Each has a single axon that projects along a single lamina optic cartridge within which it makes extensive synaptic connections before terminating in the proximal lamina. It is strongly presynaptic to lamina monopolar neurons L1 and L2 and the lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011).
database_cross_reference: FlyBrain_NDB:10111
database_cross_reference: VFB:FBbt_00006007
has exact synonym: photoreceptor cell R1-6
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006007
in subset: cur

Axiom
annotated source: outer photoreceptor cell
annotated property: definition
annotated target: An eye photoreceptor cell whose rhabdomere is part of the outer trapezoid of rhabdomeres of each ommatidium. There are six of these per ommatidium. Each has a single axon that projects along a single lamina optic cartridge within which it makes extensive synaptic connections before terminating in the proximal lamina. It is strongly presynaptic to lamina monopolar neurons L1 and L2 and the lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011).
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

inner photoreceptor cell
type: Class
subclass of: eye photoreceptor cell
definition: Eye photoreceptor cell whose rhabdomere is located in the center of each ommatidium.
database_cross_reference: VFB:FBbt_00006008
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006008
in subset: cur

Axiom
annotated source: inner photoreceptor cell
annotated property: definition
annotated target: Eye photoreceptor cell whose rhabdomere is located in the center of each ommatidium.
database_cross_reference: FlyBase:FBrf0064798

eye photoreceptor cell
type: Class
subclass of: CL_0000210
subclass of: sensory organ cell
subclass of: FBbt_00007251
subclass of: FBbt_00058210
subclass of: FBbt_00058244
subclass of: FBbt_00059276
subclass of: Restriction
  on property: part of
  some values from: ommatidium
subclass of: Restriction
  on property: has soma location
  some values from: retina
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048002
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: adult optic lobe
definition: Photoreceptor cell that forms the core of each ommatidium in the adult eye. Eight of these photoreceptors are arranged in each ommatidial core, bundled like the staves of a barrel. Each has a photosensitive rhabdomere that projects into the barrel cavity and adjacent supporting membrane, the stalk (Wolff and Ready, 1993). Each extends an axon into the optic lobe. Activation of the photoreceptor by light results in depolarization and in histamine release at the synapses of these axons (Sarthy, 1991).
has alternative id: FBbt:00003709
database_cross_reference: CL:2000019
database_cross_reference: VFB:FBbt_00006009
has exact synonym: lamina receptor cell
has exact synonym: retinula cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006009
in subset: cur
comment: Note - eyelet photoreceptors are NOT sub-types.

Axiom
annotated source: eye photoreceptor cell
annotated property: definition
annotated target: Photoreceptor cell that forms the core of each ommatidium in the adult eye. Eight of these photoreceptors are arranged in each ommatidial core, bundled like the staves of a barrel. Each has a photosensitive rhabdomere that projects into the barrel cavity and adjacent supporting membrane, the stalk (Wolff and Ready, 1993). Each extends an axon into the optic lobe. Activation of the photoreceptor by light results in depolarization and in histamine release at the synapses of these axons (Sarthy, 1991).
database_cross_reference: FlyBase:FBrf0054495
database_cross_reference: FlyBase:FBrf0064798

Axiom
annotated source: eye photoreceptor cell
annotated property: hasExactSynonym
annotated target: retinula cell
database_cross_reference: FlyBase:FBrf0012179

gonadal somatic stem cell
type: Class
equivalent class: Class
  intersection of: FBbt_00007344
  intersection of: Restriction
    on property: part of
    some values from: gonad
subclass of: FBbt_00007344
subclass of: Restriction
  on property: part of
  some values from: gonad
definition: Any somatic stem cell (FBbt:00007344) that is part of some gonad (FBbt:00004858).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006010
in subset: cur

Axiom
annotated source: gonadal somatic stem cell
annotated property: definition
annotated target: Any somatic stem cell (FBbt:00007344) that is part of some gonad (FBbt:00004858).
database_cross_reference: FBC:Autogenerated

pharate adult
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: pupa
definition: The developing adult after pupal-adult apolysis, i.e. from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion.
database_cross_reference: UBERON:6006011
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006011
in subset: FB gloss
in subset: cur

Axiom
annotated source: pharate adult
annotated property: definition
annotated target: The developing adult after pupal-adult apolysis, i.e. from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion.
database_cross_reference: FlyBase:FBrf0049147

external sensory organ precursor cell IIIb
type: Class
subclass of: external sensory organ precursor cell
subclass of: Restriction
  on property: develops from
  some values from: external sensory organ precursor cell IIb
definition: Precursor cell daughter of an external sensory organ precursor cell IIb. In the development of antennal olfactory sensilla, there are two classes, pNa and pNb, which each divide asymmetrically to produce up to four types of sensory neuron per sensillum (Endo et al., 2012; Chai et al., 2019). In the microchaete lineage, there is one of these cells (the other daughter of pIIb is a glial cell), which divides to produce one neuron and one apical sheath cell (Gho et al., 1999).
has exact synonym: pIIIb
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006022
in subset: cur
comment: The reference paper (Gho et al., 1999) provides evidence for the existence of this intermediate stage between pIIb and the birth of the eo neuron in the wing mechanoreceptor development. There may be some question as to whether this can be generalized to all external sensory organs, but in the absence of evidence that the development of these organs is distinct I have applied this stage to all external sensory organ development. ds060308.

Axiom
annotated source: external sensory organ precursor cell IIIb
annotated property: definition
annotated target: Precursor cell daughter of an external sensory organ precursor cell IIb. In the development of antennal olfactory sensilla, there are two classes, pNa and pNb, which each divide asymmetrically to produce up to four types of sensory neuron per sensillum (Endo et al., 2012; Chai et al., 2019). In the microchaete lineage, there is one of these cells (the other daughter of pIIb is a glial cell), which divides to produce one neuron and one apical sheath cell (Gho et al., 1999).
database_cross_reference: FlyBase:FBrf0111371
database_cross_reference: FlyBase:FBrf0217319
database_cross_reference: FlyBase:FBrf0241429

somatic cell of ovariole
type: Class
equivalent class: Class
  intersection of: FBbt_00100318
  intersection of: Restriction
    on property: part of
    some values from: ovariole
subclass of: FBbt_00048491
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: ovariole
definition: Somatic cell that is part of the ovariole. This does not include the ovarian sheath.
has broad synonym: somatic cell of ovary
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006030
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: somatic cell of ovariole
annotated property: definition
annotated target: Somatic cell that is part of the ovariole. This does not include the ovarian sheath.
database_cross_reference: FBC:VJ
database_cross_reference: FlyBase:FBrf0218159
database_cross_reference: https://orcid.org/0000-0002-8728-0281

somatic cell of testis
type: Class
equivalent class: Class
  intersection of: FBbt_00100318
  intersection of: Restriction
    on property: part of
    some values from: testis
subclass of: FBbt_00048490
subclass of: FBbt_00100318
subclass of: Restriction
  on property: part of
  some values from: testis
definition: A(n) somatic cell that is part of a(n) testis.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006031
in subset: cur

Axiom
annotated source: somatic cell of testis
annotated property: definition
annotated target: A(n) somatic cell that is part of a(n) testis.
database_cross_reference: FBC:Autogenerated

antennal nerve
type: Class
subclass of: supraesophageal nerve
subclass of: Restriction
  on property: innervates
  some values from: antennal lobe
definition: Nerve that carries axons to the adult or larval antennal lobe.
database_cross_reference: VFB:FBbt_00006045
has exact synonym: AN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006045
in subset: cur
in subset: larval OF

Axiom
annotated source: antennal nerve
annotated property: definition
annotated target: Nerve that carries axons to the adult or larval antennal lobe.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

escort cell
type: Class
subclass of: somatic cell of ovariole
subclass of: Restriction
  on property: part of
  some values from: germarium
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00048549
subclass of: Restriction
  on property: expresses
  some values from: FBgn0014163
definition: Somatic cell type with squamous morphology found in regions 1 and 2a of the germarium. These cells send out thin cytoplasmic processes which envelop cystoblasts and cysts for several days prior to follicle cell formation. Their extensions move posteriorly with developing cystoblasts, while the cell bodies are stable and do not cross the 2a/2b boundary in the germarium. More posteriorly located escort cells have a higher rate of apoptosis.
has exact synonym: EC
has exact synonym: IGS
has exact synonym: inner germarial sheath cell
has exact synonym: inner germarium sheath cell
has exact synonym: inner sheath cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006049
in subset: RD
in subset: cur
comment: Labelled by expression of fax (Rust et al., 2020).

Axiom
annotated source: escort cell
annotated property: definition
annotated target: Somatic cell type with squamous morphology found in regions 1 and 2a of the germarium. These cells send out thin cytoplasmic processes which envelop cystoblasts and cysts for several days prior to follicle cell formation. Their extensions move posteriorly with developing cystoblasts, while the cell bodies are stable and do not cross the 2a/2b boundary in the germarium. More posteriorly located escort cells have a higher rate of apoptosis.
database_cross_reference: FlyBase:FBrf0190200
database_cross_reference: FlyBase:FBrf0247148

Axiom
annotated source: escort cell
annotated property: hasExactSynonym
annotated target: EC
database_cross_reference: FlyBase:FBrf0235678

Axiom
annotated source: escort cell
annotated property: hasExactSynonym
annotated target: inner germarial sheath cell
database_cross_reference: FlyBase:FBrf0247148

Axiom
annotated source: escort cell
annotated property: hasExactSynonym
annotated target: inner germarium sheath cell
database_cross_reference: FlyBase:FBrf0190200

appendage
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Organism subdivision that protrudes from the head or trunk.
database_cross_reference: UBERON:0000026
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007000
in subset: cur

Axiom
annotated source: appendage
annotated property: definition
annotated target: Organism subdivision that protrudes from the head or trunk.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

anatomical structure
type: Class
subclass of: material anatomical entity
definition: Material anatomical entity that has inherent 3D shape, whose parts are all connected and that is generated by coordinated expression of the organism's own genome.
database_cross_reference: CARO:0000003
database_cross_reference: UBERON:0000061
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007001
in subset: cur
in subset: larval OF

Axiom
annotated source: anatomical structure
annotated property: definition
annotated target: Material anatomical entity that has inherent 3D shape, whose parts are all connected and that is generated by coordinated expression of the organism's own genome.
database_cross_reference: https://orcid.org/0000-0001-9114-8737
database_cross_reference: https://orcid.org/0000-0002-7073-9172

cell
type: Class
subclass of: anatomical structure
definition: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: CARO:0000013
database_cross_reference: CL:0000000
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007002
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: cell
annotated property: definition
annotated target: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

portion of tissue
type: Class
subclass of: FBbt_00100313
definition: Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.
database_cross_reference: CARO:0000043
database_cross_reference: UBERON:0000479
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007003
in subset: cur

Axiom
annotated source: portion of tissue
annotated property: definition
annotated target: Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

male organism
type: Class
subclass of: organism
definition: Gonochoristic organism that can produce male gametes.
database_cross_reference: CARO:0000027
database_cross_reference: UBERON:0003101
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007004
in subset: cur

Axiom
annotated source: male organism
annotated property: definition
annotated target: Gonochoristic organism that can produce male gametes.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

epithelium
type: Class
subclass of: portion of tissue
definition: Portion of tissue, that consists of one or more layers of cells with distinct apical-basal polarity, connected to each other by cell junctions.
database_cross_reference: UBERON:0000483
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007005
in subset: cur

Axiom
annotated source: epithelium
annotated property: definition
annotated target: Portion of tissue, that consists of one or more layers of cells with distinct apical-basal polarity, connected to each other by cell junctions.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

developing material anatomical entity
type: Class
subclass of: material anatomical entity
database_cross_reference: CARO:0000066
database_cross_reference: UBERON:0005423
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007006
in subset: cur

somatic precursor cell
type: Class
subclass of: developing material anatomical entity
subclass of: FBbt_00100318
definition: Somatic cell that is a precursor to a mature cell.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007008
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: somatic precursor cell
annotated property: definition
annotated target: Somatic cell that is a precursor to a mature cell.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

organism subdivision
type: Class
subclass of: FBbt_00100313
definition: Anatomical structure that is a primary subdivision of whole organism. The mereological sum of these is the whole organism.
database_cross_reference: CARO:0000032
database_cross_reference: UBERON:0000475
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007009
in subset: cur
in subset: larval OF

Axiom
annotated source: organism subdivision
annotated property: definition
annotated target: Anatomical structure that is a primary subdivision of whole organism. The mereological sum of these is the whole organism.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

multi-tissue structure
type: Class
subclass of: FBbt_00100313
definition: Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which, through specific morphogenetic processes, forms a single distinct structural unit demarcated by bona fide boundaries from other distinct structural units of different types.
database_cross_reference: CARO:0000055
database_cross_reference: UBERON:0000481
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007010
in subset: cur
in subset: larval OF

Axiom
annotated source: multi-tissue structure
annotated property: definition
annotated target: Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which, through specific morphogenetic processes, forms a single distinct structural unit demarcated by bona fide boundaries from other distinct structural units of different types.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

female organism
type: Class
subclass of: organism
definition: Gonochoristic organism that can produce female gametes.
database_cross_reference: CARO:0000028
database_cross_reference: UBERON:0003100
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007011
in subset: cur

Axiom
annotated source: female organism
annotated property: definition
annotated target: Gonochoristic organism that can produce female gametes.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

cell component
type: Class
subclass of: anatomical structure
definition: Anatomical structure that is a direct part of a cell.
database_cross_reference: CARO:0000014
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007012
in subset: cur

Axiom
annotated source: cell component
annotated property: definition
annotated target: Anatomical structure that is a direct part of a cell.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

acellular anatomical structure
type: Class
subclass of: anatomical structure
database_cross_reference: CARO:0000040
database_cross_reference: UBERON:0000476
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007013
in subset: cur

stem cell
type: Class
subclass of: cell
definition: Undifferentiated cell which retains its identity while budding off cells which differentiate.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007014
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: stem cell
annotated property: definition
annotated target: Undifferentiated cell which retains its identity while budding off cells which differentiate.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

immaterial anatomical entity
type: Class
subclass of: FBbt_10000000
definition: Anatomical entity that has no mass.
database_cross_reference: CARO:0000007
database_cross_reference: UBERON:0000466
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007015
in subset: cur

Axiom
annotated source: immaterial anatomical entity
annotated property: definition
annotated target: Anatomical entity that has no mass.
database_cross_reference: CARO:0000007

material anatomical entity
type: Class
subclass of: FBbt_10000000
database_cross_reference: CARO:0000006
database_cross_reference: UBERON:0000465
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007016
in subset: cur
in subset: larval OF

appendage segment
type: Class
subclass of: organism subdivision
subclass of: Restriction
  on property: part of
  some values from: appendage
definition: Division of an appendage along its proximal-distal axis.
database_cross_reference: UBERON:0010758
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007018
in subset: cur

Axiom
annotated source: appendage segment
annotated property: definition
annotated target: Division of an appendage along its proximal-distal axis.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

adult midgut epithelium
type: Class
equivalent class: Class
  intersection of: FBbt_00047109
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: FBbt_00047109
subclass of: Restriction
  on property: part of
  some values from: adult midgut
definition: Epithelial monolayer of endodermal origin, which lines the adult midgut and which is overlain by the peritrophic membrane.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007026
in subset: cur

Axiom
annotated source: adult midgut epithelium
annotated property: definition
annotated target: Epithelial monolayer of endodermal origin, which lines the adult midgut and which is overlain by the peritrophic membrane.
database_cross_reference: FlyBase:FBrf0191249

cuboidal/columnar epithelium
type: Class
subclass of: epithelium
definition: An epithelium consisting of columnar shaped cells.
database_cross_reference: UBERON:0000485
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007027
in subset: cur

Axiom
annotated source: cuboidal/columnar epithelium
annotated property: definition
annotated target: An epithelium consisting of columnar shaped cells.
database_cross_reference: FlyBase:FBrf0239342

squamous epithelium
type: Class
subclass of: epithelium
definition: A type of epithelium that is made up of flattened cells which are arranged with their long axes in the plane of the epithelium.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007028
in subset: cur

Axiom
annotated source: squamous epithelium
annotated property: definition
annotated target: A type of epithelium that is made up of flattened cells which are arranged with their long axes in the plane of the epithelium.
database_cross_reference: FlyBase:FBrf0239342

adult posterior midgut epithelium
type: Class
subclass of: cuboidal/columnar epithelium
subclass of: Restriction
  on property: part of
  some values from: adult midgut epithelium
definition: A columnar - cuboidal epithelial monolayer with a brush border consisting predominantly of large polyploid enterocytes tied together by smooth septate junctions. Scattered through this epithelium are clusters of diploid intestinal stem cells and occasional enteroendocrine cells.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007036
in subset: cur

Axiom
annotated source: adult posterior midgut epithelium
annotated property: definition
annotated target: A columnar - cuboidal epithelial monolayer with a brush border consisting predominantly of large polyploid enterocytes tied together by smooth septate junctions. Scattered through this epithelium are clusters of diploid intestinal stem cells and occasional enteroendocrine cells.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0139657
database_cross_reference: FlyBase:FBrf0191251

enterocyte of posterior adult midgut epithelium
type: Class
equivalent class: Class
  intersection of: enterocyte
  intersection of: Restriction
    on property: part of
    some values from: FBbt_00047155
subclass of: FBbt_00047182
subclass of: Restriction
  on property: part of
  some values from: adult posterior midgut epithelium
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047155
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00110206
definition: A large, polyploid, cuboidal or low-columnar epithelial cell of the adult posterior midgut. It has its nucleus in the middle and a mass of microvilli (brush border) on its apical surface. On its basal side, extensive infoldings of the plasma membrane form a labyrinth which fills the lower half of the cell. It is attached to adjacent enterocytes by smooth septate junctions.
has exact synonym: pEC
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007037
in subset: cur

Axiom
annotated source: enterocyte of posterior adult midgut epithelium
annotated property: definition
annotated target: A large, polyploid, cuboidal or low-columnar epithelial cell of the adult posterior midgut. It has its nucleus in the middle and a mass of microvilli (brush border) on its apical surface. On its basal side, extensive infoldings of the plasma membrane form a labyrinth which fills the lower half of the cell. It is attached to adjacent enterocytes by smooth septate junctions.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0139657
database_cross_reference: FlyBase:FBrf0191251
database_cross_reference: FlyBase:FBrf0244662

Axiom
annotated source: enterocyte of posterior adult midgut epithelium
annotated property: hasExactSynonym
annotated target: pEC
database_cross_reference: FlyBase:FBrf0244662

enteroendocrine cell
type: Class
subclass of: epithelial cell
subclass of: FBbt_00007294
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047109
subclass of: Restriction
  on property: expresses
  some values from: FBgn0004595
definition: Diploid endocrine cell which is part of the adult or larval midgut epithelium.
has exact synonym: ee
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007038
in subset: cur
comment: These cells can be identified by expression of prospero in the adult (Zeng and Hou, 2015) and larval (Mathur et al., 2010 - FBrf0209706) gut.

Axiom
annotated source: enteroendocrine cell
annotated property: definition
annotated target: Diploid endocrine cell which is part of the adult or larval midgut epithelium.
database_cross_reference: FlyBase:FBrf0191251
database_cross_reference: FlyBase:FBrf0207758
database_cross_reference: FlyBase:FBrf0227510

Axiom
annotated source: enteroendocrine cell
annotated property: hasExactSynonym
annotated target: ee
database_cross_reference: FlyBase:FBrf0191251

intestinal stem cell
type: Class
subclass of: FBbt_00007344
subclass of: Restriction
  on property: part of
  some values from: adult midgut epithelium
subclass of: Restriction
  on property: expresses
  some values from: FBgn0000463
subclass of: Restriction
  on property: expresses
  some values from: FBgn0001981
definition: Wedge shaped diploid cell found in scattered clusters in the midgut epithelium. The broad end of the wedge lies on the basement membrane and contains the nucleus. The tapering apex of the cell extends up towards the lumen.
has exact synonym: ISC
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007039
in subset: cur
comment: Can be identified by expression of Delta (and escargot) (Zeng and Hou, 2015).

Axiom
annotated source: intestinal stem cell
annotated property: definition
annotated target: Wedge shaped diploid cell found in scattered clusters in the midgut epithelium. The broad end of the wedge lies on the basement membrane and contains the nucleus. The tapering apex of the cell extends up towards the lumen.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0191251
database_cross_reference: FlyBase:FBrf0227510

Axiom
annotated source: intestinal stem cell
annotated property: hasExactSynonym
annotated target: ISC
database_cross_reference: FlyBase:FBrf0191251

adult anterior midgut epithelium
type: Class
subclass of: cuboidal/columnar epithelium
subclass of: FBbt_00047124
subclass of: Restriction
  on property: part of
  some values from: adult midgut epithelium
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047154
definition: Anteriormost part of the adult midgut epithelium, bordering the acidic middle midgut at its posterior end. Enterocytes have distinct morphologies in different subregions of this portion of the epithelium.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007040
in subset: cur

Axiom
annotated source: adult anterior midgut epithelium
annotated property: definition
annotated target: Anteriormost part of the adult midgut epithelium, bordering the acidic middle midgut at its posterior end. Enterocytes have distinct morphologies in different subregions of this portion of the epithelium.
database_cross_reference: FlyBase:FBrf0221749
database_cross_reference: FlyBase:FBrf0223413

enterocyte
type: Class
subclass of: epithelial cell
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047166
definition: Specialized epithelial cell of the gut. A large, polyploid, cuboidal or low-columnar epithelial cell with its nucleus in the middle and a mass of microvilli (brush border) on its apical surface. On its basal side, extensive infoldings of the plasma membrane form a labyrinth which fills the lower half of the cell. It is attached to adjacent enterocytes by smooth septate junctions.
has exact synonym: EC
has OBO namespace: fly_anatomy.ontology
has related synonym: absorptive cell
id: FBbt:00007042
in subset: cur

Axiom
annotated source: enterocyte
annotated property: definition
annotated target: Specialized epithelial cell of the gut. A large, polyploid, cuboidal or low-columnar epithelial cell with its nucleus in the middle and a mass of microvilli (brush border) on its apical surface. On its basal side, extensive infoldings of the plasma membrane form a labyrinth which fills the lower half of the cell. It is attached to adjacent enterocytes by smooth septate junctions.
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0139657
database_cross_reference: FlyBase:FBrf0191251

Axiom
annotated source: enterocyte
annotated property: hasExactSynonym
annotated target: EC
database_cross_reference: FlyBase:FBrf0191251

Axiom
annotated source: enterocyte
annotated property: hasRelatedSynonym
annotated target: absorptive cell
database_cross_reference: FlyBase:FBrf0206835

trunk ectoderm
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: ectoderm
definition: The region of the ectoderm posterior to the cephalic furrow.
database_cross_reference: UBERON:6007045
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007045

Axiom
annotated source: trunk ectoderm
annotated property: definition
annotated target: The region of the ectoderm posterior to the cephalic furrow.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

dorsal ectoderm derivative
type: Class
equivalent class: Class
  intersection of: FBbt_10000000
  intersection of: Restriction
    on property: develops from
    some values from: dorsal ectoderm
subclass of: FBbt_00025990
subclass of: Restriction
  on property: develops from
  some values from: dorsal ectoderm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007046

adult cerebrum
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: part of
  some values from: FBbt_00047887
subclass of: Restriction
  on property: part of
  some values from: FBbt_00110636
definition: The cerebral ganglion, minus the optic lobes. It includes part of the protocerebrum (without the optic lobes), the deutocerebrum and the tritocerebrum.
database_cross_reference: VFB:FBbt_00007050
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007050

Axiom
annotated source: adult cerebrum
annotated property: definition
annotated target: The cerebral ganglion, minus the optic lobes. It includes part of the protocerebrum (without the optic lobes), the deutocerebrum and the tritocerebrum.
database_cross_reference: FlyBase:FBrf0224194

procephalic glioblast
type: Class
equivalent class: Class
  intersection of: glioblast
  intersection of: Restriction
    on property: part of
    some values from: central brain primordium
subclass of: embryonic glioblast
subclass of: Restriction
  on property: part of
  some values from: central brain primordium
definition: Any glioblast (FBbt:00005145) that is part of some central brain primordium (FBbt:00005542).
database_cross_reference: VFB:FBbt_00007051
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007051

Axiom
annotated source: procephalic glioblast
annotated property: definition
annotated target: Any glioblast (FBbt:00005145) that is part of some central brain primordium (FBbt:00005542).
database_cross_reference: FBC:Autogenerated

adult lateral horn
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00111688
definition: Dorsolateral horn-shaped synaptic neuropil domain of the adult protocerebrum that houses the terminals of various antennal lobe projection neurons (Ito et al., 2014). It is not separated from other neuropils by a glial sheath, but by the extent of arborization and synapsing of these antennal lobe projection neurons (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00007053
has exact synonym: LH
has OBO namespace: fly_anatomy.ontology
has related synonym: lateral protocerebrum
id: FBbt:00007053
in subset: BrainName

Axiom
annotated source: adult lateral horn
annotated property: definition
annotated target: Dorsolateral horn-shaped synaptic neuropil domain of the adult protocerebrum that houses the terminals of various antennal lobe projection neurons (Ito et al., 2014). It is not separated from other neuropils by a glial sheath, but by the extent of arborization and synapsing of these antennal lobe projection neurons (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult lateral horn
annotated property: hasExactSynonym
annotated target: LH
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: adult lateral horn
annotated property: hasRelatedSynonym
annotated target: lateral protocerebrum
database_cross_reference: FlyBase:FBrf0224194

superior lateral protocerebrum
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045030
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval superior lateral protocerebrum
definition: Lateral synaptic neuropil domain of the adult superior neuropils. It lies behind the anterior optic tubercle, in front of the mushroom body calyx and above the superior clamp and lateral horn. Its boundary with the anterior optic tubercle (AOTU), mushroom body calyx and lateral horn is demarcated by the extent of arborization of visual projection neurons and antennal lobe projection neurons. Boundaries with the superior clamp, anterior and posterior ventro-lateral protocerebrum are defined using clearly distinguishable fiber bundles.
has alternative id: FBbt:00045031
database_cross_reference: VFB:FBbt_00007054
has exact synonym: SLP
has exact synonym: adult superior lateral protocerebrum
has OBO namespace: fly_anatomy.ontology
has related synonym: DLP
has related synonym: IDLP
has related synonym: slpr
id: FBbt:00007054
in subset: BrainName
comment: Boundaries defined by Ito et al. (2014) (used to define this term) differ slightly from those defined for slpr in Otsuna and Ito, 2006. The anterior superior SLP corresponds to mslpr and the posterior superior SLP to pslpr of Otsuna and Ito (2006). The SLP also corresponds to the lateral part of the dorsolateral protocerebrum (DLP) and lateral part of the inner dorsolateral protocerebrum (IDLP) of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: superior lateral protocerebrum
annotated property: definition
annotated target: Lateral synaptic neuropil domain of the adult superior neuropils. It lies behind the anterior optic tubercle, in front of the mushroom body calyx and above the superior clamp and lateral horn. Its boundary with the anterior optic tubercle (AOTU), mushroom body calyx and lateral horn is demarcated by the extent of arborization of visual projection neurons and antennal lobe projection neurons. Boundaries with the superior clamp, anterior and posterior ventro-lateral protocerebrum are defined using clearly distinguishable fiber bundles.
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00045031

Axiom
annotated source: superior lateral protocerebrum
annotated property: hasExactSynonym
annotated target: SLP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: superior lateral protocerebrum
annotated property: hasRelatedSynonym
annotated target: DLP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: superior lateral protocerebrum
annotated property: hasRelatedSynonym
annotated target: IDLP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: superior lateral protocerebrum
annotated property: hasRelatedSynonym
annotated target: slpr
database_cross_reference: FlyBase:FBrf0193607

superior medial protocerebrum
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045030
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00111203
definition: Medial synaptic neuropil domain of the adult superior neuropils that lies above the area flanked by the mushroom lobes, pedunculus, and calyx. It is separated from the pedunculus by the superior clamp and insulated from the medial lobe by the crepine. The fan-shaped body protrudes deeply into this neuropil, separating it into anterior (ASMP) and posterior (PSMP) regions.
has broad synonym: IDLP
database_cross_reference: VFB:FBbt_00007055
has exact synonym: SMP
has narrow synonym: SDFP
has OBO namespace: fly_anatomy.ontology
has related synonym: impr
has related synonym: smpr
id: FBbt:00007055
in subset: BrainName
comment: Different regions of the SMP correspond to the subdivisions of the smpr and impr (Otsuna and Ito, 2006). The anterior and posterior regions of the superior SMP match part of smpr; the anterior and posterior regions of the inferior SMP match part of impr. The SMP also corresponds to the superior dorsofrontal protocerebrum (SDFP) and to the medial part of the inner dorsolateral protocerebrum (IDLP) of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: superior medial protocerebrum
annotated property: definition
annotated target: Medial synaptic neuropil domain of the adult superior neuropils that lies above the area flanked by the mushroom lobes, pedunculus, and calyx. It is separated from the pedunculus by the superior clamp and insulated from the medial lobe by the crepine. The fan-shaped body protrudes deeply into this neuropil, separating it into anterior (ASMP) and posterior (PSMP) regions.
database_cross_reference: FBC:AJ
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00007055

Axiom
annotated source: superior medial protocerebrum
annotated property: hasBroadSynonym
annotated target: IDLP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: superior medial protocerebrum
annotated property: hasExactSynonym
annotated target: SMP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: superior medial protocerebrum
annotated property: hasNarrowSynonym
annotated target: SDFP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: superior medial protocerebrum
annotated property: hasRelatedSynonym
annotated target: impr
database_cross_reference: FlyBase:FBrf0212889

Axiom
annotated source: superior medial protocerebrum
annotated property: hasRelatedSynonym
annotated target: smpr
database_cross_reference: FlyBase:FBrf0193607

ventrolateral protocerebrum
type: Class
subclass of: FBbt_00041000
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045021
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval ventrolateral protocerebrum
definition: A large mass of synaptic neuropil domains in the anterior brain of the adult, between the antennal lobe and the optic lobe (Ito et al., 2014). It can be divided into an anterior and posterior regions (AVLP and PVLP) (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00007058
has exact synonym: VLP
has exact synonym: anterior optic foci
has exact synonym: ventro-lateral adult protocerebrum
has exact synonym: ventro-lateral protocerebrum
has exact synonym: vlpr
has narrow synonym: OG
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007058
in subset: BrainName
comment: Currently some uncertainty about whether this is truly protocerebral - may actually be part of deutocerebrum (Strausfeld has characterized it as such). This should be clarified as a result of Volker Hartenstein's lineage mapping work. The VLP corresponds to almost all of the vlpr of Otsuna and Ito (2006) and to the ventrolateral protocerebrum (VLP) and optic glomerulus (OG) of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: ventrolateral protocerebrum
annotated property: definition
annotated target: A large mass of synaptic neuropil domains in the anterior brain of the adult, between the antennal lobe and the optic lobe (Ito et al., 2014). It can be divided into an anterior and posterior regions (AVLP and PVLP) (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: VLP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: vlpr
database_cross_reference: FlyBase:FBrf0193607

Axiom
annotated source: ventrolateral protocerebrum
annotated property: hasNarrowSynonym
annotated target: OG
database_cross_reference: FlyBase:FBrf0212704

anterior optic tubercle
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: part of
  some values from: FBbt_00045021
subclass of: Restriction
  on property: develops from
  some values from: FBbt_00111205
definition: Synaptic neuropil domain of the adult protocerebrum that receives extensive arborizations from visual projection neurons from the lobula and the medulla, projecting via the anterior optic tract. It protrudes from the anterior-most area of the ventro-lateral neuropils and is slightly detached from the ventro-lateral protocerebrum. This neuropil is absent from the larval brain, being formed during pupal development.
database_cross_reference: VFB:FBbt_00007059
has exact synonym: AOTU
has exact synonym: OPTU
has exact synonym: OTU
has exact synonym: optic tubercle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007059
in subset: BrainName
comment: Otsuna and Ito (2006) suggest that the optic tubercle may be divided into three regions according to the density of arborizations. The medial-most (optu1) and lateral-most (optu3) contain dense arborizations of the Lcn10 neurons, whilst the area between these regions (optu2) is essentially devoid of the lobula columnar neurons.

Axiom
annotated source: anterior optic tubercle
annotated property: definition
annotated target: Synaptic neuropil domain of the adult protocerebrum that receives extensive arborizations from visual projection neurons from the lobula and the medulla, projecting via the anterior optic tract. It protrudes from the anterior-most area of the ventro-lateral neuropils and is slightly detached from the ventro-lateral protocerebrum. This neuropil is absent from the larval brain, being formed during pupal development.
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00007059

Axiom
annotated source: anterior optic tubercle
annotated property: hasExactSynonym
annotated target: AOTU
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: anterior optic tubercle
annotated property: hasExactSynonym
annotated target: OPTU
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: anterior optic tubercle
annotated property: hasExactSynonym
annotated target: OTU
database_cross_reference: FlyBase:FBrf0211884

multi-cell-component structure
type: Class
subclass of: anatomical structure
definition: A structure mainly consisting of cell components, rather than complete cells.
database_cross_reference: UBERON:0005162
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007060
in subset: larval OF
comment: May contain some complete cells in addition to partial ones (e.g. glia in nervous system regions).

Axiom
annotated source: multi-cell-component structure
annotated property: definition
annotated target: A structure mainly consisting of cell components, rather than complete cells.
database_cross_reference: https://orcid.org/0000-0002-1373-1705
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval ventromedial cerebrum
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: larval deutocerebrum
definition: One of a group of synaptic neuropil domains of the larval brain which are located ventral to the mushroom body and are grouped around the long axon tracts connecting the larval protocerebrum to the ventral nerve cord. This medially located compartment contacts the antennal lobe posteriorly. The lateral cervical tract ascends through the center of this compartment. It is the larval counterpart of the adult ventromedial neuropils.
database_cross_reference: VFB:FBbt_00007063
database_cross_reference: larvalbrain_neuropil:437
database_cross_reference: larvalbrain_neuropil:615
has exact synonym: BPM
has exact synonym: baso-posterior medial compartment
has exact synonym: basoposterior medial compartment
has exact synonym: larval VMC
has exact synonym: larval baso-posterior midbrain
has exact synonym: larval ventromedial cerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007063
comment: Note - description of relative location of brain structures in this definition is based on Younossi-Hartenstein et al., 2003 description of the first instar larval brain and Pereanu et al., 2010 third instar larval brain.

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: definition
annotated target: One of a group of synaptic neuropil domains of the larval brain which are located ventral to the mushroom body and are grouped around the long axon tracts connecting the larval protocerebrum to the ventral nerve cord. This medially located compartment contacts the antennal lobe posteriorly. The lateral cervical tract ascends through the center of this compartment. It is the larval counterpart of the adult ventromedial neuropils.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: hasExactSynonym
annotated target: BPM
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: hasExactSynonym
annotated target: basoposterior medial compartment
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: hasExactSynonym
annotated target: larval VMC
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: hasExactSynonym
annotated target: larval ventromedial cerebrum
database_cross_reference: FlyBase:FBrf0211016

embryonic/larval superior lateral protocerebrum
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00052193
definition: Thin layer of larval synaptic neuropil found lateral to the superior medial protocerebrum, separated from it by axon bundles of the DPlc lineages (Hartenstein et al., 2015). It is the precursor to the adult superior lateral protocerebrum and lateral horn domains (Pereanu et al., 2010; Hartenstein et al., 2015).
has broad synonym: CPLd
has broad synonym: dorsal centro-posterior lateral synaptic neuropil domain
database_cross_reference: VFB:FBbt_00007064
database_cross_reference: larvalbrain_neuropil:408
database_cross_reference: larvalbrain_neuropil:586
has exact synonym: larval SLP
has exact synonym: larval SLP/LH
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007064
in subset: larval OF

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: definition
annotated target: Thin layer of larval synaptic neuropil found lateral to the superior medial protocerebrum, separated from it by axon bundles of the DPlc lineages (Hartenstein et al., 2015). It is the precursor to the adult superior lateral protocerebrum and lateral horn domains (Pereanu et al., 2010; Hartenstein et al., 2015).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: hasBroadSynonym
annotated target: CPLd
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: hasBroadSynonym
annotated target: dorsal centro-posterior lateral synaptic neuropil domain
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: hasExactSynonym
annotated target: larval SLP
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: hasExactSynonym
annotated target: larval SLP/LH
database_cross_reference: FlyBase:FBrf0229672

embryonic/larval lateral accessory lobe
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: larval protocerebrum
definition: Larval synaptic neuropil domain that is located ventral to the mushroom body medial lobe and posterior to the antennal lobe and periesophageal neuropils (Hartenstein et al., 2015). It is the larval counterpart of the adult lateral accessory lobe (Pereanu et al., 2010).
database_cross_reference: VFB:FBbt_00007067
database_cross_reference: larvalbrain_neuropil:375
database_cross_reference: larvalbrain_neuropil:553
has exact synonym: BC
has exact synonym: baso-central synaptic neuropil domain
has exact synonym: basocentral compartment
has exact synonym: centro-posterior medial neuropil compartment
has exact synonym: larval LAL
has exact synonym: larval lateral accessory lobe
has exact synonym: larval ventral body
has exact synonym: primordium of LAL
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007067
comment: Note - description of relative location of brain structures in this definition is based on Younossi-Hartenstein et al., 2003 description of the first instar larval brain and Pereanu et al., 2010 third instar larval brain.

Axiom
annotated source: embryonic/larval lateral accessory lobe
annotated property: definition
annotated target: Larval synaptic neuropil domain that is located ventral to the mushroom body medial lobe and posterior to the antennal lobe and periesophageal neuropils (Hartenstein et al., 2015). It is the larval counterpart of the adult lateral accessory lobe (Pereanu et al., 2010).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval lateral accessory lobe
annotated property: hasExactSynonym
annotated target: BC
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval lateral accessory lobe
annotated property: hasExactSynonym
annotated target: basocentral compartment
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval lateral accessory lobe
annotated property: hasExactSynonym
annotated target: larval LAL
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval lateral accessory lobe
annotated property: hasExactSynonym
annotated target: larval lateral accessory lobe
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval lateral accessory lobe
annotated property: hasExactSynonym
annotated target: primordium of LAL
database_cross_reference: FlyBase:FBrf0211016

embryonic/larval ventrolateral protocerebrum
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: larval protocerebrum
definition: One of a group of synaptic neuropil domains of the larval brain which are located ventral to the mushroom body and are grouped around the long axon tracts connecting the larval protocerebrum to the ventral nerve cord. This compartment contacts the antennal lobe posteriorly, and is lateral to the lateral accessory lobe and ventromedial cerebrum. It grows anteriorly during larval development. It is the larval counterpart of the adult ventrolateral protocerebrum.
database_cross_reference: VFB:FBbt_00007068
database_cross_reference: larvalbrain_neuropil:422
database_cross_reference: larvalbrain_neuropil:600
has exact synonym: BPL
has exact synonym: baso-posterior lateral synaptic neuropil compartment
has exact synonym: baso-posterior lateral synaptic neuropil domain
has exact synonym: basoposterior lateral compartment
has exact synonym: larval VLP
has exact synonym: larval ventro-lateral protocerebrum
has exact synonym: larval ventrolateral protocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007068
comment: Developmental relation to adult synaptic neuropil domains comes from a personal communication from Volker Hartenstein. Note - description of relative location of brain structures in this definition is based on Younossi-Hartenstein et al., 2003 description of the first instar larval brain and Pereanu et al., 2010 third instar larval brain.

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: definition
annotated target: One of a group of synaptic neuropil domains of the larval brain which are located ventral to the mushroom body and are grouped around the long axon tracts connecting the larval protocerebrum to the ventral nerve cord. This compartment contacts the antennal lobe posteriorly, and is lateral to the lateral accessory lobe and ventromedial cerebrum. It grows anteriorly during larval development. It is the larval counterpart of the adult ventrolateral protocerebrum.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: BPL
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: basoposterior lateral compartment
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: larval VLP
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: larval ventrolateral protocerebrum
database_cross_reference: FlyBase:FBrf0211016

larval posterior inferior protocerebrum
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00052192
definition: Compartment of the larval inferior protocerebrum found posterior medial to the larval superior clamp (medial inferior protocerebrum) (Hartenstein et al., 2015). The adult central complex arises from secondary axonal tracts of several lineages that invade this region and displace it during pupal development (Pereanu et al., 2010). A small region at its posterior edge remains and gives rise to the adult inferior clamp (posterior inferior protocerebrum) (Pereanu et al., 2010).
database_cross_reference: UBERON:6007070
database_cross_reference: VFB:FBbt_00007070
database_cross_reference: larvalbrain_neuropil:404
database_cross_reference: larvalbrain_neuropil:582
has exact synonym: CPM
has exact synonym: centro-posterior medial synaptic neuropil domain
has exact synonym: centroposterior medial compartment
has exact synonym: embryonic/larval posterior inferior protocerebrum
has exact synonym: larval IPp
has narrow synonym: larval inferior clamp
has OBO namespace: fly_anatomy.ontology
has related synonym: primordium of CCX
has related synonym: primordium of central complex
id: FBbt:00007070
comment: Developmental relation to adult synaptic neuropil domain is a PC from Volker Hartenstein. Note - description of relative location of brain structures in this definition is based on Younossi-Hartenstein et al., 2003 description of the first instar larval brain and Pereanu et al., 2010 third instar larval brain.

Axiom
annotated source: larval posterior inferior protocerebrum
annotated property: definition
annotated target: Compartment of the larval inferior protocerebrum found posterior medial to the larval superior clamp (medial inferior protocerebrum) (Hartenstein et al., 2015). The adult central complex arises from secondary axonal tracts of several lineages that invade this region and displace it during pupal development (Pereanu et al., 2010). A small region at its posterior edge remains and gives rise to the adult inferior clamp (posterior inferior protocerebrum) (Pereanu et al., 2010).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: larval posterior inferior protocerebrum
annotated property: hasExactSynonym
annotated target: CPM
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: larval posterior inferior protocerebrum
annotated property: hasExactSynonym
annotated target: centroposterior medial compartment
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: larval posterior inferior protocerebrum
annotated property: hasExactSynonym
annotated target: larval IPp
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: larval posterior inferior protocerebrum
annotated property: hasRelatedSynonym
annotated target: primordium of CCX
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: larval posterior inferior protocerebrum
annotated property: hasRelatedSynonym
annotated target: primordium of central complex
database_cross_reference: FlyBase:FBrf0211016

commissure
type: Class
equivalent class: Class
  intersection of: tract
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0000618
subclass of: tract
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0000618
subclass of: Restriction
  on property: overlaps
  some values from: FBbt_00111739
definition: A fiber bundle that crosses the midline, connecting both hemispheres (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00007084
has exact synonym: midline crossing tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007084

Axiom
annotated source: commissure
annotated property: definition
annotated target: A fiber bundle that crosses the midline, connecting both hemispheres (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

perineurial glial sheath
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: perineurium
subclass of: Restriction
  on property: attached to
  some values from: subperineurial glial sheath
definition: The outermost cellular layer of the nervous system, probably of mesodermal origin (Hartenstein and Jan, 1992). This layer consists of glial cells, which participate in nutrient uptake and establish a first diffusion barrier (Limmer et al., 2014).
database_cross_reference: VFB:FBbt_00007089
has exact synonym: apical glial cell
has exact synonym: perineural sheath
has exact synonym: perineurial sheath
has OBO namespace: fly_anatomy.ontology
has related synonym: neural lamella
id: FBbt:00007089
comment: Evidence of mesodermal origin comes from the observation that embryos lacking mesoderm lack this cell layer and the overlying neural lamella (Edwards et al., 1993).

Axiom
annotated source: perineurial glial sheath
annotated property: definition
annotated target: The outermost cellular layer of the nervous system, probably of mesodermal origin (Hartenstein and Jan, 1992). This layer consists of glial cells, which participate in nutrient uptake and establish a first diffusion barrier (Limmer et al., 2014).
database_cross_reference: FlyBase:FBrf0057603
database_cross_reference: FlyBase:FBrf0058936
database_cross_reference: FlyBase:FBrf0226917

Axiom
annotated source: perineurial glial sheath
annotated property: hasExactSynonym
annotated target: apical glial cell
database_cross_reference: FlyBase:FBrf0206543

Axiom
annotated source: perineurial glial sheath
annotated property: hasRelatedSynonym
annotated target: neural lamella
database_cross_reference: FlyBase:FBrf0214261

perineurium
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: The outer two layers of glial cells that cover the central nervous system and the nerves. The outer layer is the perineurial glial sheath (sometimes referred to as the perineurial sheath outer layer); the inner layer is the subperineurial glial sheath (sometimes referred to as the perineurial sheath inner layer).
database_cross_reference: VFB:FBbt_00007090
has OBO namespace: fly_anatomy.ontology
has related synonym: blood-brain barrier
id: FBbt:00007090
comment: Some authors use this term only to refer to the double layer of cells covering the CNS (e.g. Hartenstein and Jan, 1992), while other authors use it more broadly to include the covering of nerves (e.g. Banerjee et al., 2006). This ontology uses the term in its broad sense. 'Blood-brain barrier' may refer to this (e.g. Limmer et al., 2014) or the subperineurial glial sheath alone (e.g. Morante et al., 2013).

Axiom
annotated source: perineurium
annotated property: definition
annotated target: The outer two layers of glial cells that cover the central nervous system and the nerves. The outer layer is the perineurial glial sheath (sometimes referred to as the perineurial sheath outer layer); the inner layer is the subperineurial glial sheath (sometimes referred to as the perineurial sheath inner layer).
database_cross_reference: FlyBase:FBrf0057603
database_cross_reference: FlyBase:FBrf0191040
database_cross_reference: FlyBase:FBrf0226917
database_cross_reference: FlyBase:FBrf0239343

Axiom
annotated source: perineurium
annotated property: hasRelatedSynonym
annotated target: blood-brain barrier
database_cross_reference: FlyBase:FBrf0226917

subperineurial glial sheath
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: perineurium
subclass of: Restriction
  on property: attached to
  some values from: perineurial glial sheath
definition: Inner glial cell layer of the perineurium that is probably not derived from the mesoderm (Edwards et al., 1994). This layer form an ion permeability barrier, functionally similar to the endothelial cells of the mammalian blood-brain barrier (Limmer et al., 2014).
database_cross_reference: VFB:FBbt_00007091
has exact synonym: barrier glial cell layer
has exact synonym: sub-perineurial glial sheath
has OBO namespace: fly_anatomy.ontology
has related synonym: blood-brain barrier
id: FBbt:00007091
comment: That the subperineurial glial cells do not derive from the mesoderm is suggested by Edwards et al. (1994), in which they show the presence of these cells in delta (FBgn0000463) mutant embryos. 'Blood-brain barrier' may refer to this (e.g. Morante et al., 2013) or the perineurium (e.g. Limmer et al., 2014), which includes this and the perineurial glial sheath.

Axiom
annotated source: subperineurial glial sheath
annotated property: definition
annotated target: Inner glial cell layer of the perineurium that is probably not derived from the mesoderm (Edwards et al., 1994). This layer form an ion permeability barrier, functionally similar to the endothelial cells of the mammalian blood-brain barrier (Limmer et al., 2014).
database_cross_reference: FlyBase:FBrf0057603
database_cross_reference: FlyBase:FBrf0058936
database_cross_reference: FlyBase:FBrf0226917
database_cross_reference: FlyBase:FBrf0239343

Axiom
annotated source: subperineurial glial sheath
annotated property: hasRelatedSynonym
annotated target: blood-brain barrier
database_cross_reference: FlyBase:FBrf0223187

cell body rind of adult mushroom body calyx
type: Class
subclass of: FBbt_00100200
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: part of
  some values from: FBbt_00052048
subclass of: Restriction
  on property: part of
  some values from: FBbt_00111153
subclass of: Restriction
  on property: continuous with
  some values from: FBbt_00007385
definition: Region of the cell body rind overlying the mushroom body calyx (Ito et al., 2014). It contains the cell bodies of the Kenyon cells (Aso et al., 2009).
database_cross_reference: VFB:FBbt_00007112
has exact synonym: cell body rind of adult mushroom body
has exact synonym: mushroom body cortex
has exact synonym: rCA
has exact synonym: rCAp
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007112
comment: rCAp is the only subregion of rCA listed in Ito et al. (2014) and no other mushroom body rinds are listed.

Axiom
annotated source: cell body rind of adult mushroom body calyx
annotated property: definition
annotated target: Region of the cell body rind overlying the mushroom body calyx (Ito et al., 2014). It contains the cell bodies of the Kenyon cells (Aso et al., 2009).
database_cross_reference: FlyBase:FBrf0207600
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult mushroom body calyx
annotated property: hasExactSynonym
annotated target: rCA
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: cell body rind of adult mushroom body calyx
annotated property: hasExactSynonym
annotated target: rCAp
database_cross_reference: FlyBase:FBrf0224194

neuroblast MBp
type: Class
subclass of: protocerebral neuroblast
definition: Neuroblast that is the precursor to the Kenyon cells (Kunz et al., 2012). There are four of these per hemisphere and they each arise from a distinct neuroectodermal progenitor and produce morphologically distinct primary lineages (Kunz et al., 2012). They continue to divide from the embryonic to the late pupal stage (Lee et al., 1999; Kunz et al., 2012). All four produce largely identical lineages postembryonically (Ito et al., 2013; Yu et al., 2013), sequentially producing gamma, alpha'/beta' and alpha/beta Kenyon cells (Lee et al., 1999; Kunz et al., 2012). In the adult, each lineage remains distinct within the calyx and pedunculus, but the axons reorganize and intermingle within the lobes (Li et al., 2020).
database_cross_reference: VFB:FBbt_00007113
has exact synonym: MB-Nb
has exact synonym: MBNB
has exact synonym: MBp1-4
has exact synonym: mushroom body neuroblast
has exact synonym: neuroblast MB
has exact synonym: neuroblast MBp
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007113
comment: See Ito et al. (2013) figure S1 for distinction between MBp1-4.

Axiom
annotated source: neuroblast MBp
annotated property: definition
annotated target: Neuroblast that is the precursor to the Kenyon cells (Kunz et al., 2012). There are four of these per hemisphere and they each arise from a distinct neuroectodermal progenitor and produce morphologically distinct primary lineages (Kunz et al., 2012). They continue to divide from the embryonic to the late pupal stage (Lee et al., 1999; Kunz et al., 2012). All four produce largely identical lineages postembryonically (Ito et al., 2013; Yu et al., 2013), sequentially producing gamma, alpha'/beta' and alpha/beta Kenyon cells (Lee et al., 1999; Kunz et al., 2012). In the adult, each lineage remains distinct within the calyx and pedunculus, but the axons reorganize and intermingle within the lobes (Li et al., 2020).
database_cross_reference: FlyBase:FBrf0092568
database_cross_reference: FlyBase:FBrf0111409
database_cross_reference: FlyBase:FBrf0218649
database_cross_reference: FlyBase:FBrf0221412
database_cross_reference: FlyBase:FBrf0221438
database_cross_reference: FlyBase:FBrf0248215

Axiom
annotated source: neuroblast MBp
annotated property: hasExactSynonym
annotated target: MBNB
database_cross_reference: FlyBase:FBrf0218649

Axiom
annotated source: neuroblast MBp
annotated property: hasExactSynonym
annotated target: MBp1-4
database_cross_reference: FlyBase:FBrf0221412

Axiom
annotated source: neuroblast MBp
annotated property: hasExactSynonym
annotated target: neuroblast MB
database_cross_reference: FlyBase:FBrf0221438

Axiom
annotated source: neuroblast MBp
annotated property: hasExactSynonym
annotated target: neuroblast MBp
has synonym type: HARTENSTEIN BRAIN LINEAGE

Axiom
annotated source: neuroblast MBp
annotated property: hasExactSynonym
annotated target: neuroblast MBp
has synonym type: ITO LEE BRAIN LINEAGE

cell body rind of the central nervous system
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Superficial neuronal layer of the central nervous system, composed of glia and the cell bodies of neurons (soma). The cell body rind lies under the perineurium.
database_cross_reference: VFB:FBbt_00007114
has exact synonym: cortex of the central nervous system
has exact synonym: perikaryal rind
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007114

Axiom
annotated source: cell body rind of the central nervous system
annotated property: definition
annotated target: Superficial neuronal layer of the central nervous system, composed of glia and the cell bodies of neurons (soma). The cell body rind lies under the perineurium.
database_cross_reference: FlyBase:FBrf0239343

Axiom
annotated source: cell body rind of the central nervous system
annotated property: hasExactSynonym
annotated target: perikaryal rind
database_cross_reference: FlyBase:FBrf0207181

larval neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: neuroblast
subclass of: Restriction
  on property: part of
  some values from: larval central nervous system
definition: Any neuroblast of the larva.
has broad synonym: embryonic/larval neuroblast
database_cross_reference: VFB:FBbt_00007115
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007115
in subset: cur

Axiom
annotated source: larval neuroblast
annotated property: definition
annotated target: Any neuroblast of the larva.
database_cross_reference: FlyBase:FBrf0047815

presumptive embryonic/larval system
type: Class
equivalent class: Class
  intersection of: FBbt_00040003
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: developing embryonic structure
subclass of: FBbt_00040003
definition: The sum of all the developing presumptive components of a specific embryonic/larval system in an embryo.
database_cross_reference: UBERON:6007116
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007116

Axiom
annotated source: presumptive embryonic/larval system
annotated property: definition
annotated target: The sum of all the developing presumptive components of a specific embryonic/larval system in an embryo.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

neuropil glial sheath
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Glial layer that largely surrounds a region of synaptic neuropil in the central nervous system (Younossi-Hartenstein et al., 2003). It is mainly formed by synaptic neuropil ensheathing glia, but these cells also frequently branch into neuropil domains and the layer also contains nuclei of reticular glia (Kremer et al., 2017).
database_cross_reference: VFB:FBbt_00007117
has exact synonym: glial boundary
has exact synonym: glial septum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007117

Axiom
annotated source: neuropil glial sheath
annotated property: definition
annotated target: Glial layer that largely surrounds a region of synaptic neuropil in the central nervous system (Younossi-Hartenstein et al., 2003). It is mainly formed by synaptic neuropil ensheathing glia, but these cells also frequently branch into neuropil domains and the layer also contains nuclei of reticular glia (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: neuropil glial sheath
annotated property: hasExactSynonym
annotated target: glial boundary
database_cross_reference: FlyBase:FBrf0206543

Axiom
annotated source: neuropil glial sheath
annotated property: hasExactSynonym
annotated target: glial septum
database_cross_reference: FlyBase:FBrf0155900

embryonic/larval crepine
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: part of
  some values from: FBbt_00052192
definition: Small synaptic neuropil domain of the larval protocerebrum that surrounds the medial lobe of the mushroom body (Pereanu et al., 2010; Hartenstein et al., 2015). It is the larval counterpart of the adult crepine (anterior inferior protocerebrum) (Pereanu et al., 2010).
database_cross_reference: VFB:FBbt_00007118
database_cross_reference: larvalbrain_neuropil:287
database_cross_reference: larvalbrain_neuropil:465
has exact synonym: CA
has exact synonym: centro-anterior synaptic neuropil domain
has exact synonym: centroanterior compartment
has exact synonym: larval IPa
has exact synonym: larval anterior inferior protocerebrum
has exact synonym: larval crepine
has exact synonym: primordium of IPa
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007118
comment: Note - description of relative location of brain structures in this definition is based on Younossi-Hartenstein et al., 2003 description of the first instar larval brain and Pereanu et al., 2010 third instar larval brain.

Axiom
annotated source: embryonic/larval crepine
annotated property: definition
annotated target: Small synaptic neuropil domain of the larval protocerebrum that surrounds the medial lobe of the mushroom body (Pereanu et al., 2010; Hartenstein et al., 2015). It is the larval counterpart of the adult crepine (anterior inferior protocerebrum) (Pereanu et al., 2010).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval crepine
annotated property: hasExactSynonym
annotated target: CA
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval crepine
annotated property: hasExactSynonym
annotated target: centroanterior compartment
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval crepine
annotated property: hasExactSynonym
annotated target: larval IPa
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval crepine
annotated property: hasExactSynonym
annotated target: larval crepine
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval crepine
annotated property: hasExactSynonym
annotated target: primordium of IPa
database_cross_reference: FlyBase:FBrf0211016

embryonic/larval antennal lobe
type: Class
subclass of: antennal lobe
subclass of: FBbt_00051405
subclass of: Restriction
  on property: part of
  some values from: larval deutocerebrum
definition: Paired synaptic neuropil domain of the larval deutocerebrum, located ventral to the mushroom body, that is the major target of innervation for axons carried by the antennal nerve. It is also connected to the antero-basal tract (ABT). Its posterior boundary contacts the lateral accessory lobe, ventromedial cerebrum, ventrolateral protocerebrum and periesophageal neuropils. It is the larval counterpart of the adult antennal lobe, and consists of around 22 glomeruli.
has alternative id: FBbt:00007062
database_cross_reference: VFB:FBbt_00007127
database_cross_reference: larvalbrain_neuropil:374
database_cross_reference: larvalbrain_neuropil:552
has exact synonym: BA
has exact synonym: LAL
has exact synonym: antennal compartment
has exact synonym: baso-anterior synaptic neuropil domain
has exact synonym: basoanterior compartment
has exact synonym: larval AL
has exact synonym: larval antennal lobe
has exact synonym: larval olfactory lobe
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007127
in subset: larval OF
comment: Note - description of relative location of brain structures in this definition is based on Younossi-Hartenstein et al., 2003 description of the first instar larval brain and Pereanu et al., 2010 third instar larval brain.

Axiom
annotated source: embryonic/larval antennal lobe
annotated property: definition
annotated target: Paired synaptic neuropil domain of the larval deutocerebrum, located ventral to the mushroom body, that is the major target of innervation for axons carried by the antennal nerve. It is also connected to the antero-basal tract (ABT). Its posterior boundary contacts the lateral accessory lobe, ventromedial cerebrum, ventrolateral protocerebrum and periesophageal neuropils. It is the larval counterpart of the adult antennal lobe, and consists of around 22 glomeruli.
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0208205
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval antennal lobe
annotated property: hasExactSynonym
annotated target: BA
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval antennal lobe
annotated property: hasExactSynonym
annotated target: LAL
database_cross_reference: FlyBase:FBrf0147119

Axiom
annotated source: embryonic/larval antennal lobe
annotated property: hasExactSynonym
annotated target: basoanterior compartment
database_cross_reference: FlyBase:FBrf0155900

antero-basal tract
type: Class
subclass of: FBbt_00007426
subclass of: Restriction
  on property: part of
  some values from: larval brain
subclass of: Restriction
  on property: innervates
  some values from: embryonic/larval antennal lobe
definition: Tract of the larval brain which is connected to the baso-anterior synaptic neuropil domain (BA; antennal compartment). This tract travels along the neuropil glial sheath which forms the boundary between baso-anterior (BA) and baso-central (BC) synaptic neuropil domains. The tract then turns dorsally to make the antennal root of the antenno-cerebral tract (ACT).
database_cross_reference: VFB:FBbt_00007128
has exact synonym: ABT
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007128
in subset: larval OF

Axiom
annotated source: antero-basal tract
annotated property: definition
annotated target: Tract of the larval brain which is connected to the baso-anterior synaptic neuropil domain (BA; antennal compartment). This tract travels along the neuropil glial sheath which forms the boundary between baso-anterior (BA) and baso-central (BC) synaptic neuropil domains. The tract then turns dorsally to make the antennal root of the antenno-cerebral tract (ACT).
database_cross_reference: FlyBase:FBrf0155899
database_cross_reference: FlyBase:FBrf0155900

embryonic/larval periesophageal neuropils
type: Class
subclass of: FBbt_00040007
subclass of: Restriction
  on property: overlaps
  some values from: larval tritocerebrum
definition: Larval counterpart to the adult periesophageal neuropils (Pereanu et al., 2010). It is located adjacent to the esophagus and guides the medial cervical tract (Younossi-Hartenstein et al., 2003; Hartenstein et al., 2015). Its anterior portion corresponds to the tritocerebrum (Hartenstein et al., 2015).
database_cross_reference: VFB:FBbt_00007129
has exact synonym: Bcv
has exact synonym: baso-cervical synaptic neuropil domain
has exact synonym: basocervical compartment
has exact synonym: larval PENP
has exact synonym: larval PONP
has exact synonym: larval periesophageal neuropils
has exact synonym: larval perioesophageal neuropils
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007129

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: definition
annotated target: Larval counterpart to the adult periesophageal neuropils (Pereanu et al., 2010). It is located adjacent to the esophagus and guides the medial cervical tract (Younossi-Hartenstein et al., 2003; Hartenstein et al., 2015). Its anterior portion corresponds to the tritocerebrum (Hartenstein et al., 2015).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: Bcv
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: basocervical compartment
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: larval PENP
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: larval PONP
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: larval periesophageal neuropils
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: larval perioesophageal neuropils
database_cross_reference: FlyBase:FBrf0211016

male germline cyst
type: Class
subclass of: germline cyst
subclass of: FBbt_00048490
subclass of: Restriction
  on property: part of
  some values from: testis
definition: Unit of spermatogenic differentiation consisting of a pair of cyst cells enclosing the developing germline cells.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007136
in subset: FlyTed
in subset: cur

Axiom
annotated source: male germline cyst
annotated property: definition
annotated target: Unit of spermatogenic differentiation consisting of a pair of cyst cells enclosing the developing germline cells.
database_cross_reference: FlyBase:FBrf0064778

female germline cyst
type: Class
subclass of: germline cyst
subclass of: FBbt_00048491
subclass of: Restriction
  on property: part of
  some values from: ovariole
subclass of: Restriction
  on property: develops from
  some values from: cystoblast
definition: A cyst of female germ cells interconnected by ring canals. Each cyst originates from a single cystoblast which divides to form 16 cyst cells. These become enveloped in a follicle cell epithelium as they pass through region 2 of the germarium. Cysts that have left the germarium are termed egg chambers.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007137

Axiom
annotated source: female germline cyst
annotated property: definition
annotated target: A cyst of female germ cells interconnected by ring canals. Each cyst originates from a single cystoblast which divides to form 16 cyst cells. These become enveloped in a follicle cell epithelium as they pass through region 2 of the germarium. Cysts that have left the germarium are termed egg chambers.
database_cross_reference: FlyBase:FBrf0064777

eye disc posterior to the morphogenetic furrow
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: eye disc
definition: Portion of the eye disc which is posterior to the morphogenetic furrow. It contains developing ommatidial clusters whose maturity increases with distance posterior to the furrow.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007143

Axiom
annotated source: eye disc posterior to the morphogenetic furrow
annotated property: definition
annotated target: Portion of the eye disc which is posterior to the morphogenetic furrow. It contains developing ommatidial clusters whose maturity increases with distance posterior to the furrow.
database_cross_reference: FlyBase:FBrf0064798

adult protocerebrum
type: Class
equivalent class: Class
  intersection of: protocerebrum
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: protocerebrum
subclass of: FBbt_00052718
subclass of: Restriction
  on property: part of
  some values from: FBbt_00110638
subclass of: Restriction
  on property: overlaps
  some values from: adult ocular segment
subclass of: Restriction
  on property: overlaps
  some values from: adult labral segment
definition: Protocerebrum of the adult brain.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-06-13T10:49:41Z
database_cross_reference: UBERON:6007145
database_cross_reference: VFB:FBbt_00007145
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007145

Axiom
annotated source: adult protocerebrum
annotated property: definition
annotated target: Protocerebrum of the adult brain.
database_cross_reference: FlyBase:FBrf0224194

adult deutocerebrum
type: Class
equivalent class: Class
  intersection of: FBbt_00052718
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: deutocerebrum
subclass of: FBbt_00052718
subclass of: Restriction
  on property: part of
  some values from: adult antennal segment
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: overlaps
  some values from: FBbt_00110638
subclass of: Restriction
  on property: overlaps
  some values from: FBbt_00110639
definition: Deutocerebrum of the adult brain. Substantial portions are below the level of the esophagus (Ito et al., 2014).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-06-13T10:52:46Z
database_cross_reference: VFB:FBbt_00007146
has exact synonym: adult deuterocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007146

Axiom
annotated source: adult deutocerebrum
annotated property: definition
annotated target: Deutocerebrum of the adult brain. Substantial portions are below the level of the esophagus (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult deutocerebrum
annotated property: hasExactSynonym
annotated target: adult deuterocerebrum
database_cross_reference: FlyBase:FBrf0224194

adult tritocerebrum
type: Class
equivalent class: Class
  intersection of: FBbt_00052718
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: tritocerebrum
subclass of: FBbt_00052718
subclass of: Restriction
  on property: part of
  some values from: adult intercalary segment
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: overlaps
  some values from: FBbt_00110638
subclass of: Restriction
  on property: overlaps
  some values from: FBbt_00110639
definition: Tritocerebrum of the adult brain. Substantial portions are below the level of the esophagus (Ito et al., 2014).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-06-13T10:57:05Z
database_cross_reference: VFB:FBbt_00007147
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007147

Axiom
annotated source: adult tritocerebrum
annotated property: definition
annotated target: Tritocerebrum of the adult brain. Substantial portions are below the level of the esophagus (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0074226
database_cross_reference: FlyBase:FBrf0224194

embryonic/larval antennal lobe tract
type: Class
equivalent class: Class
  intersection of: antennal lobe tract
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: antennal lobe tract
subclass of: Restriction
  on property: part of
  some values from: larval brain
subclass of: Restriction
  on property: innervates
  some values from: larval posterior inferior protocerebrum
subclass of: Restriction
  on property: innervates
  some values from: embryonic/larval antennal lobe
subclass of: Restriction
  on property: innervates
  some values from: FBbt_00111204
subclass of: Restriction
  on property: continuous with
  some values from: antero-basal tract
definition: Tract of the larva that connects the antennal lobe to other neuropils in the protocerebrum, including mushroom body and lateral horn (Nassif et al., 2003; Hartenstein et al., 2015). There are three of these, the medial, mediolateral and lateral antennal lobe tracts (Das et al., 2013). They are larval counterparts to the adult antennal lobe tracts (Nassif et al., 2003).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-06-13T11:43:51Z
database_cross_reference: VFB:FBbt_00007148
database_cross_reference: larvalbrain_axon_tract:3
database_cross_reference: larvalbrain_axon_tract:4
has exact synonym: embryonic/larval antenno-cerebral tract
has exact synonym: larval ACT
has exact synonym: larval antenno-cerebral tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007148
in subset: larval OF

Axiom
annotated source: embryonic/larval antennal lobe tract
annotated property: definition
annotated target: Tract of the larva that connects the antennal lobe to other neuropils in the protocerebrum, including mushroom body and lateral horn (Nassif et al., 2003; Hartenstein et al., 2015). There are three of these, the medial, mediolateral and lateral antennal lobe tracts (Das et al., 2013). They are larval counterparts to the adult antennal lobe tracts (Nassif et al., 2003).
database_cross_reference: FlyBase:FBrf0155899
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0220443
database_cross_reference: FlyBase:FBrf0229672
database_cross_reference: FlyBase:FBrf0232785

Axiom
annotated source: embryonic/larval antennal lobe tract
annotated property: hasExactSynonym
annotated target: larval ACT
database_cross_reference: FlyBase:FBrf0220443

Axiom
annotated source: embryonic/larval antennal lobe tract
annotated property: hasExactSynonym
annotated target: larval antenno-cerebral tract
database_cross_reference: FlyBase:FBrf0220443

segment of antenna
type: Class
equivalent class: Class
  intersection of: appendage segment
  intersection of: Restriction
    on property: part of
    some values from: antenna
subclass of: appendage segment
subclass of: Restriction
  on property: part of
  some values from: antenna
definition: Any appendage segment (FBbt:00007018) that is part of some antenna (FBbt:00004511).
database_cross_reference: UBERON:6007149
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007149

Axiom
annotated source: segment of antenna
annotated property: definition
annotated target: Any appendage segment (FBbt:00007018) that is part of some antenna (FBbt:00004511).
database_cross_reference: FBC:Autogenerated

segment of leg
type: Class
equivalent class: Class
  intersection of: appendage segment
  intersection of: Restriction
    on property: part of
    some values from: leg
subclass of: appendage segment
subclass of: Restriction
  on property: part of
  some values from: leg
definition: Any appendage segment (FBbt:00007018) that is part of some leg (FBbt:00004640).
database_cross_reference: UBERON:6007150
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007150

Axiom
annotated source: segment of leg
annotated property: definition
annotated target: Any appendage segment (FBbt:00007018) that is part of some leg (FBbt:00004640).
database_cross_reference: FBC:Autogenerated

adult antennal sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: part of
    some values from: antenna
subclass of: adult sense organ
subclass of: antennal sense organ
subclass of: Restriction
  on property: part of
  some values from: antenna
definition: Any sense organ (FBbt:00005155) that is part of some antenna (FBbt:00004511).
database_cross_reference: VFB:FBbt_00007151
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007151

Axiom
annotated source: adult antennal sense organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is part of some antenna (FBbt:00004511).
database_cross_reference: FBC:Autogenerated

sensillum
type: Class
equivalent class: Class
  intersection of: FBbt_00007229
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: sense organ
subclass of: FBbt_00007229
definition: A sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organized unit with a largely bona fide boundary.
database_cross_reference: UBERON:0002536
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007152
in subset: FB gloss
in subset: larval OF

Axiom
annotated source: sensillum
annotated property: definition
annotated target: A sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organized unit with a largely bona fide boundary.
database_cross_reference: FlyBase:FBrf0111704

embryonic/larval antennal lobe glomerulus
type: Class
equivalent class: Class
  intersection of: antennal lobe glomerulus
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: antennal lobe glomerulus
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval antennal lobe
subclass of: Restriction
  on property: part of
  some values from: FBbt_00007688
definition: Antennal lobe glomerulus of the larva. There are 21 glomeruli, each innervated by a single type of olfactory receptor neuron (Masuda-Nakagawa et al., 2009).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-09-08T10:34:24Z
database_cross_reference: VFB:FBbt_00007153
has exact synonym: larval antennal lobe glomerulus
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007153
in subset: larval OF

Axiom
annotated source: embryonic/larval antennal lobe glomerulus
annotated property: definition
annotated target: Antennal lobe glomerulus of the larva. There are 21 glomeruli, each innervated by a single type of olfactory receptor neuron (Masuda-Nakagawa et al., 2009).
database_cross_reference: FlyBase:FBrf0208205

adult maxillary neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052718
  intersection of: Restriction
    on property: part of
    some values from: maxillary segment
subclass of: FBbt_00111044
subclass of: Restriction
  on property: part of
  some values from: adult maxillary segment
subclass of: Restriction
  on property: develops from
  some values from: larval maxillary neuromere
definition: Neuromere of the adult gnathal ganglion that develops from the larval maxillary neuromere. It is located between the mandibular and labial neuromeres, but segmental architecture is less well defined in the adult.
contributor: https://orcid.org/0000-0002-7073-9172
database_cross_reference: VFB:FBbt_00007158
has OBO namespace: fly_anatomy.ontology
has related synonym: maxillary segment of adult subesophageal ganglion
id: FBbt:00007158
in subset: BrainName

Axiom
annotated source: adult maxillary neuromere
annotated property: definition
annotated target: Neuromere of the adult gnathal ganglion that develops from the larval maxillary neuromere. It is located between the mandibular and labial neuromeres, but segmental architecture is less well defined in the adult.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0237252

adult mandibular neuromere
type: Class
equivalent class: Class
  intersection of: FBbt_00052718
  intersection of: Restriction
    on property: part of
    some values from: mandibular segment
subclass of: FBbt_00111044
subclass of: Restriction
  on property: part of
  some values from: adult mandibular segment
subclass of: Restriction
  on property: develops from
  some values from: larval mandibular neuromere
definition: Neuromere of the adult gnathal ganglion that develops from the larval mandibular neuromere. It is located anterior to the maxillary and labial neuromeres, but segmental architecture is less well defined in the adult.
database_cross_reference: VFB:FBbt_00007159
has OBO namespace: fly_anatomy.ontology
has related synonym: mandibular segment of adult subesophageal ganglion
id: FBbt:00007159
in subset: BrainName

Axiom
annotated source: adult mandibular neuromere
annotated property: definition
annotated target: Neuromere of the adult gnathal ganglion that develops from the larval mandibular neuromere. It is located anterior to the maxillary and labial neuromeres, but segmental architecture is less well defined in the adult.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0237252