VFB scRNAseq Ontology for dataset FBlc0006237
type: Ontology
description: An ontology of Drosophila melanogaster scRNAseq data from a single dataset (FBlc0006237). This information is taken from FlyBase, which sources it from the EMBL-EBI Single Cell Expression Atlas, which compiles scRNAseq data from multiple sources.

definition
type: AnnotationProperty
IAO_0000111: definition
IAO_0000114: IAO_0000122
definition: A property representing the English language definitions of what NCI means by the concept. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software.
definition: The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
definition: The official definition.
IAO_0000116: 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.
IAO_0000117: PERSON:Daniel Schober
IAO_0000119: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
has exact synonym: DEFINITION
label: textual definition

is a defining property chain axiom
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL

is a defining property chain axiom where second argument is reflexive
type: AnnotationProperty
definition: If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.

database_cross_reference
type: AnnotationProperty
IAO_0000112: disease characteristic (MONDO:0021125) has cross-reference (http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NCIT:C41009"^^xsd:string
definition: An annotation property that links an ontology entity or a statement to a prefixed identifier or URI.
definition: Reference database or publication source.
IAO_0000233: https://github.com/information-artifact-ontology/ontology-metadata/issues/123
contributor: https://orcid.org/0000-0002-7356-1779
label: has cross-reference

part of
type: ObjectProperty
sub property of: overlaps
inverse of: has part
type: TransitiveProperty
IAO_0000111: is part of
IAO_0000112: my brain is part of my body (continuant parthood, two material entities)
IAO_0000112: my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
IAO_0000112: this day is part of this year (occurrent parthood)
definition: a core relation that holds between a part and its whole
IAO_0000116: Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
IAO_0000116: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
IAO_0000116: Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
IAO_0000118: part_of
RO_0001900: RO_0001901
RO_0040042: BFO_0000002
RO_0040042: BFO_0000003
RO_0040042: BFO_0000004
RO_0040042: BFO_0000017
RO_0040042: BFO_0000019
RO_0040042: BFO_0000020
RO_0040042: BFO_0000031
in subset: valid for go annotation extension
in subset: valid for go gp2term
in subset: valid for go ontology
in subset: valid for gocam

has part
type: ObjectProperty
sub property of: overlaps
type: TransitiveProperty
IAO_0000111: has part
IAO_0000112: my body has part my brain (continuant parthood, two material entities)
IAO_0000112: my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
IAO_0000112: this year has part this day (occurrent parthood)
definition: a core relation that holds between a whole and its part
IAO_0000116: Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
IAO_0000116: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
IAO_0000116: Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
IAO_0000118: has_part
RO_0001900: RO_0001901
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam

realized in
type: ObjectProperty
inverse of: realizes
domain: BFO_0000017
range: BFO_0000015
IAO_0000111: realized in
IAO_0000112: this disease is realized in this disease course
IAO_0000112: this fragility is realized in this shattering
IAO_0000112: this investigator role is realized in this investigation
IAO_0000118: is realized by
IAO_0000118: realized_in
IAO_0000600: [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

realizes
type: ObjectProperty
domain: BFO_0000015
range: BFO_0000017
IAO_0000111: realizes
IAO_0000112: this disease course realizes this disease
IAO_0000112: this investigation realizes this investigator role
IAO_0000112: this shattering realizes this fragility
definition: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process
IAO_0000600: to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

preceded by
type: ObjectProperty
sub property of: ends after
inverse of: precedes
type: TransitiveProperty
domain: BFO_0000003
range: BFO_0000003
property chain axiom: part of
property chain axiom: starts during
property chain axiom: happens during
IAO_0000111: preceded by
definition: x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
IAO_0000116: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other.
IAO_0000118: is preceded by
IAO_0000118: preceded_by
source: http://www.obofoundry.org/ro/#OBO_REL:preceded_by
in subset: ro-eco

precedes
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
domain: BFO_0000003
range: BFO_0000003
property chain axiom: part of
property chain axiom: happens during
IAO_0000111: precedes
definition: x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
in subset: ro-eco

substage of
type: ObjectProperty
sub property of: occurrent part of
sub property of: happens during
type: TransitiveProperty
definition: A relation between a developmental stage and another, larger developmental stage during which it happens.
has OBO namespace: relationship
id: FBdv:00018001
comment: Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO.

Axiom
annotated source: substage of
annotated property: definition
annotated target: A relation between a developmental stage and another, larger developmental stage during which it happens.
database_cross_reference: FBC:DPG

has specified input
type: ObjectProperty
sub property of: has participant
inverse of: is specified input of
domain: planned process
IAO_0000111: has specified input
IAO_0000112: see is_input_of example_of_usage
IAO_0000114: IAO_0000122
definition: The inverse property of is specified input of
IAO_0000116: 8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works.
IAO_0000117: PERSON: Alan Ruttenberg
IAO_0000117: PERSON: Bjoern Peters
IAO_0000117: PERSON: Larry Hunter
IAO_0000117: PERSON: Melanie Coutot

is specified input of
type: ObjectProperty
sub property of: participates in
range: planned process
IAO_0000111: is specified input of
IAO_0000112: some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay
IAO_0000114: IAO_0000122
definition: A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
IAO_0000117: Alan Ruttenberg
IAO_0000117: PERSON:Bjoern Peters

has specified output
type: ObjectProperty
sub property of: has participant
inverse of: is specified output of
domain: planned process
IAO_0000111: has specified output
IAO_0000114: IAO_0000122
definition: The inverse property of is specified output of
IAO_0000117: PERSON: Alan Ruttenberg
IAO_0000117: PERSON: Bjoern Peters
IAO_0000117: PERSON: Larry Hunter
IAO_0000117: PERSON: Melanie Courtot

is specified output of
type: ObjectProperty
sub property of: participates in
range: planned process
IAO_0000111: is specified output of
IAO_0000114: IAO_0000122
definition: A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
IAO_0000117: Alan Ruttenberg
IAO_0000117: PERSON:Bjoern Peters

achieves_planned_objective
type: ObjectProperty
inverse of: objective_achieved_by
domain: planned process
range: IAO_0000005
IAO_0000111: achieves_planned_objective
IAO_0000112: A cell sorting process achieves the objective specification 'material separation objective'
IAO_0000114: IAO_0000120
definition: This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.
IAO_0000117: BP, AR, PPPB branch
IAO_0000119: PPPB branch derived
IAO_0000232: modified according to email thread from 1/23/09 in accordince with DT and PPPB branch

objective_achieved_by
type: ObjectProperty
domain: IAO_0000005
range: planned process
IAO_0000111: objective_achieved_by
IAO_0000114: IAO_0000122
definition: This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
IAO_0000117: OBI
IAO_0000119: OBI

characteristic of
type: ObjectProperty
sub property of: characteristic of part of
inverse of: has characteristic
type: FunctionalProperty
IAO_0000111: inheres in
IAO_0000112: this fragility is a characteristic of this vase
IAO_0000112: this red color is a characteristic of this apple
definition: a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
IAO_0000118: inheres_in
RO_0001900: RO_0001901
comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.

has characteristic
type: ObjectProperty
type: InverseFunctionalProperty
range: BFO_0000020
IAO_0000111: bearer of
IAO_0000112: this apple is bearer of this red color
IAO_0000112: this vase is bearer of this fragility
definition: Inverse of characteristic_of
IAO_0000116: A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
IAO_0000118: bearer_of
IAO_0000118: is bearer of
RO_0001900: RO_0001901

participates in
type: ObjectProperty
inverse of: has participant
domain: BFO_0000002
range: BFO_0000003
IAO_0000111: participates in
IAO_0000112: this blood clot participates in this blood coagulation
IAO_0000112: this input material (or this output material) participates in this process
IAO_0000112: this investigator participates in this investigation
definition: a relation between a continuant and a process, in which the continuant is somehow involved in the process
IAO_0000118: participates_in

has participant
type: ObjectProperty
domain: BFO_0000003
range: BFO_0000002
property chain axiom: has part
property chain axiom: realizes
property chain axiom: characteristic of
IAO_0000111: has participant
IAO_0000112: this blood coagulation has participant this blood clot
IAO_0000112: this investigation has participant this investigator
IAO_0000112: this process has participant this input material (or this output material)
definition: a relation between a process and a continuant, in which the continuant is somehow involved in the process
IAO_0000116: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
IAO_0000118: has_participant
source: http://www.obofoundry.org/ro/#OBO_REL:has_participant

is concretized as
type: ObjectProperty
inverse of: concretizes
domain: BFO_0000031
range: Class
  union of: BFO_0000015
  union of: BFO_0000020
IAO_0000112: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
IAO_0000112: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a generically dependent continuant and a specifically dependent continuant or process, in which the generically dependent continuant depends on some independent continuant or process in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants or processes.

concretizes
type: ObjectProperty
domain: Class
  union of: BFO_0000015
  union of: BFO_0000020
range: BFO_0000031
IAO_0000112: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
IAO_0000112: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a specifically dependent continuant or process and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. Multiple specifically dependent continuants or processes can concretize the same generically dependent continuant.

role of
type: ObjectProperty
sub property of: characteristic of
inverse of: has role
IAO_0000112: this investigator role is a role of this person
definition: a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
IAO_0000116: A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.
IAO_0000118: is role of
IAO_0000118: role_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

has role
type: ObjectProperty
sub property of: has characteristic
domain: BFO_0000004
range: BFO_0000023
IAO_0000112: this person has role this investigator role (more colloquially: this person has this role of investigator)
definition: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
IAO_0000116: A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
IAO_0000118: has_role

electrically_synapsed_to
type: ObjectProperty
sub property of: connected to
definition: A relation that holds between two neurons that are electrically coupled via gap junctions.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

innervated by
type: ObjectProperty
inverse of: innervates
domain: anatomical structure
range: UBERON_0000122
definition: relation between an anatomical structure and a neuron projection bundle that has synaptic terminals in the structure.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

has synaptic terminal of
type: ObjectProperty
sub property of: overlaps
inverse of: has synaptic terminal in
IAO_0000117: https://orcid.org/0000-0002-7073-9172
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

occurrent part of
type: ObjectProperty
sub property of: part of
sub property of: causally upstream of or within
domain: BFO_0000003
range: BFO_0000003
definition: A part of relation that applies only between occurrents.

during which ends
type: ObjectProperty
sub property of: temporally related to
inverse of: ends during
IAO_0000117: https://orcid.org/0000-0002-7073-9172
in subset: ro-eco
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

encompasses
type: ObjectProperty
sub property of: during which starts
inverse of: happens during
type: TransitiveProperty
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: di
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

ends after
type: ObjectProperty
sub property of: temporally related to
type: TransitiveProperty
property chain axiom: ends during
property chain axiom: preceded by
IAO_0000117: https://orcid.org/0000-0002-7073-9172
in subset: ro-eco
comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)

immediately preceded by
type: ObjectProperty
sub property of: preceded by
inverse of: immediately precedes
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: starts_at_end_of
comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)

during which starts
type: ObjectProperty
sub property of: temporally related to
inverse of: starts during
IAO_0000117: https://orcid.org/0000-0002-7073-9172
in subset: ro-eco
comment: Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

immediately precedes
type: ObjectProperty
sub property of: precedes
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: ends_at_start_of
IAO_0000118: meets
RO_0002575: precedes
in subset: ro-eco
comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)

starts during
type: ObjectProperty
sub property of: temporally related to
domain: BFO_0000003
range: BFO_0000003
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: io
in subset: ro-eco
comment: X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))

happens during
type: ObjectProperty
sub property of: starts during
sub property of: ends during
type: TransitiveProperty
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: d
IAO_0000118: during
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
in subset: ro-eco
comment: X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))

ends during
type: ObjectProperty
sub property of: temporally related to
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: o
IAO_0000118: overlaps
in subset: ro-eco
comment: X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y).

has soma location
type: ObjectProperty
sub property of: overlaps
domain: CL_0000540
range: UBERON_0000465
property chain axiom: part of
property chain axiom: is neuron
property chain axiom: is anatomical entity
IAO_0000114: IAO_0000125
definition: Relation between a neuron and a material anatomical entity that its soma is part of.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/BFO_0000051> some ( <http://purl.obolibrary.org/obo/GO_0043025> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)
RO_0001900: RO_0001901

fasciculates with
type: ObjectProperty
sub property of: overlaps
inverse of: has fasciculating neuron projection
domain: CL_0000540
range: UBERON_0000122
IAO_0000114: IAO_0000125
definition: relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: fasciculates with
IAO_0000426: (forall (?x ?y) (iff (fasciculates_with ?x ?y) (exists (?nps ?npbs) (and ("neuron ; CL_0000540" ?x) ("neuron projection bundle ; CARO_0001001" ?y) ("neuron projection segment ; CARO_0001502" ?nps) ("neuron projection bundle segment ; CARO_0001500' " ?npbs) (part_of ?npbs ?y) (part_of ?nps ?x) (part_of ?nps ?npbs) (forall (?npbss) (if (and ("neuron projection bundle subsegment ; CARO_0001501" ?npbss) (part_of ?npbss ?npbs) ) (overlaps ?nps ?npbss) ))))))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

synapsed by
type: ObjectProperty
sub property of: receives input from
inverse of: synapsed to
range: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
IAO_0000114: IAO_0000125
definition: Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that has_part some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

has postsynaptic terminal in
type: ObjectProperty
sub property of: has synaptic terminal in
inverse of: has presynaptic terminal in
domain: CL_0000540
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: synapsed in
IAO_0000424: http://purl.obolibrary.org/obo/BFO_0000051 some ( http://purl.org/obo/owl/GO#GO_0045211 and http://purl.obolibrary.org/obo/BFO_0000050 some ( http://purl.org/obo/owl/GO#GO_0045202 and http://purl.obolibrary.org/obo/BFO_0000050 some ?Y))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

has presynaptic terminal in
type: ObjectProperty
sub property of: has synaptic terminal in
domain: CL_0000540
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.
IAO_0000118: synapses in
IAO_0000424: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

synapsed to
type: ObjectProperty
sub property of: sends output to
domain: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
IAO_0000114: IAO_0000125
definition: Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613
comment: N1 synapsed_to some N2 Expands to: N1 SubclassOf ( has_part some ( ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( ‘synapse ; GO:0045202’ that has_part some ( ‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))

has synaptic terminal in
type: ObjectProperty
sub property of: overlaps
domain: CL_0000540
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: has synapse in
IAO_0000424: <http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

overlaps
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
property chain axiom: part of
property chain axiom: has part
IAO_0000114: IAO_0000125
definition: x overlaps y if and only if there exists some z such that x has part z and z part of y
IAO_0000424: http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)
RO_0001900: RO_0001901
in subset: valid for go annotation extension
in subset: valid for gocam
in subset: ro-eco

Axiom
annotated source: overlaps
annotated property: propertyChainAxiom
annotated target: has part
annotated target: part of
RO_0002582: true

has fasciculating neuron projection
type: ObjectProperty
sub property of: overlaps
domain: UBERON_0000122
range: Class
  union of: CL_0000540
  union of: Restriction
    on property: part of
    some values from: CL_0000540
IAO_0000114: IAO_0000125
definition: The relation between a neuron projection bundle and a neuron projection that is fasciculated with it.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: has fasciculating component
IAO_0000426: (forall (?x ?y) (iff (has_fasciculating_neuron_projection ?x ?y) (exists (?nps ?npbs) (and ("neuron projection bundle ; CARO_0001001" ?x) ("neuron projection ; GO0043005" ?y) ("neuron projection segment ; CARO_0001502" ?nps) ("neuron projection bundle segment ; CARO_0001500" ?npbs) (part_of ?nps ?y) (part_of ?npbs ?x) (part_of ?nps ?npbs) (forall (?npbss) (if (and ("neuron projection bundle subsegment ; CARO_0001501" ?npbss) (part_of ?npbss ?npbs) ) (overlaps ?nps ?npbss) ))))))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

innervates
type: ObjectProperty
domain: UBERON_0000122
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000424: <http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))
RO_0001900: RO_0001901
cites as authority: http://www.ncbi.nlm.nih.gov/pubmed/22402613

continuous with
type: ObjectProperty
sub property of: mereotopologically related to
type: SymmetricProperty
domain: BFO_0000004
range: BFO_0000004
IAO_0000114: IAO_0000125
definition: X continuous_with Y if and only if X and Y share a fiat boundary.
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000118: connected to
IAO_0000232: The label for this relation was previously connected to. I relabeled this to "continuous with". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)
RO_0001900: RO_0001901

connected to
type: ObjectProperty
sub property of: mereotopologically related to
domain: Restriction
  on property: part of
  some values from: system
range: Restriction
  on property: part of
  some values from: system
IAO_0000112: a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).
definition: a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/22293552

develops from
type: ObjectProperty
sub property of: has developmental contribution from
sub property of: developmentally preceded by
inverse of: develops into
type: TransitiveProperty
domain: BFO_0000004
range: BFO_0000004
IAO_0000114: IAO_0000125
definition: x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y
IAO_0000117: https://orcid.org/0000-0001-9114-8737
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: https://orcid.org/0000-0003-1980-3228
comment: This is the transitive form of the develops from relation

develops into
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to develop into
sub property of: has potential to directly develop into
type: TransitiveProperty
IAO_0000114: IAO_0000125
definition: inverse of develops from
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000117: https://orcid.org/0000-0002-7073-9172
IAO_0000117: https://orcid.org/0000-0003-1980-3228
in subset: RO_0002259

expressed in
type: ObjectProperty
sub property of: genomically related to
inverse of: expresses
domain: BFO_0000002
domain: Class
  union of: BFO_0000031
  union of: BFO_0000040
range: UBERON_0000465
property chain axiom: part of
IAO_0000112: 'neural crest cell' SubClassOf expresses some 'Wnt1 gene'
IAO_0000114: IAO_0000125
definition: x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process
IAO_0000117: https://orcid.org/0000-0002-6601-2165

capable of
type: ObjectProperty
sub property of: capable of part of
domain: BFO_0000004
range: BFO_0000015
IAO_0000112: mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)
IAO_0000112: osteoclast SubClassOf 'capable of' some 'bone resorption'
definition: A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has function realized in
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20123131
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/21208450
IAO_0000232: For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".
in subset: ro-eco

capable of part of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal agent in process
property chain axiom: capable of
property chain axiom: part of
definition: c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: has function in

Axiom
annotated source: capable of part of
annotated property: propertyChainAxiom
annotated target: capable of
annotated target: part of
RO_0002582: true

temporally related to
type: ObjectProperty
domain: BFO_0000003
range: BFO_0000003
IAO_0000114: IAO_0000125
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: Allen's interval algebra
IAO_0000232: Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.
source: https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit
in subset: ro-eco
comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.

has input
type: ObjectProperty
sub property of: has participant
inverse of: input of
domain: BFO_0000015
IAO_0000114: IAO_0000125
definition: p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: consumes
in subset: valid for go annotation extension
in subset: valid for go ontology
in subset: valid for gocam
in subset: ro-eco

has developmental contribution from
type: ObjectProperty
sub property of: developmentally preceded by
inverse of: developmentally contributes to
domain: anatomical entity
range: anatomical entity
property chain axiom: has part
IAO_0000112: Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]
IAO_0000114: IAO_0000125
definition: x has developmental contribution from y iff x has some part z such that z develops from y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

developmentally contributes to
type: ObjectProperty
sub property of: developmentally succeeded by
sub property of: has potential to developmentally contribute to
property chain axiom: develops into
property chain axiom: part of
IAO_0000114: IAO_0000125
definition: inverse of has developmental contribution from
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: RO_0002259

developmentally preceded by
type: ObjectProperty
sub property of: developmentally related to
inverse of: developmentally succeeded by
domain: BFO_0000002
range: BFO_0000002
IAO_0000114: IAO_0000125
definition: Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p
IAO_0000116: false
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: In general you should not use this relation to make assertions - use one of the more specific relations below this one
comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from

developmentally succeeded by
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000125
definition: Inverse of developmentally preceded by
IAO_0000117: https://orcid.org/0000-0002-6601-2165

expresses
type: ObjectProperty
sub property of: genomically related to
IAO_0000114: IAO_0000125
definition: y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process.
IAO_0000117: https://orcid.org/0000-0002-6601-2165

characteristic of part of
type: ObjectProperty
sub property of: depends on
property chain axiom: characteristic of
property chain axiom: part of
definition: q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
IAO_0000116: Because part_of is transitive, inheres in is a sub-relation of characteristic of part of
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: inheres in part of
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/20064205
RO_0001900: RO_0001901

Axiom
annotated source: characteristic of part of
annotated property: propertyChainAxiom
annotated target: characteristic of
annotated target: part of
RO_0002582: true

mereotopologically related to
type: ObjectProperty
definition: A mereological relationship or a topological relationship
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships
RO_0001900: RO_0001901

developmentally related to
type: ObjectProperty
definition: A relationship that holds between entities participating in some developmental process (GO:0032502)
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development

functionally related to
type: ObjectProperty
definition: A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: This is a grouping relation that collects relations used for the purpose of connecting structure and function

part of structure that is capable of
type: ObjectProperty
sub property of: functionally related to
property chain axiom: part of
property chain axiom: capable of
definition: this relation holds between c and p when c is part of some c', and c' is capable of p.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: false

Axiom
annotated source: part of structure that is capable of
annotated property: propertyChainAxiom
annotated target: part of
annotated target: capable of
is a defining property chain axiom: true

genomically related to
type: ObjectProperty
domain: BFO_0000002
range: BFO_0000002
definition: holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism

member of
type: ObjectProperty
sub property of: part of
inverse of: has member
IAO_0000112: An organism that is a member of a population of organisms
definition: is member of is a mereological relation between a item and a collection.
IAO_0000118: is member of
IAO_0000118: member part of
IAO_0000119: SIO
RO_0001900: RO_0001901

has member
type: ObjectProperty
sub property of: has part
type: IrreflexiveProperty
definition: has member is a mereological relation between a collection and an item.
IAO_0000119: SIO
RO_0001900: RO_0001901

input of
type: ObjectProperty
sub property of: participates in
sub property of: functionally related to
definition: inverse of has input
IAO_0000117: https://orcid.org/0000-0002-6601-2165
in subset: RO_0002259
in subset: ro-eco

has developmental potential involving
type: ObjectProperty
sub property of: developmentally related to
domain: anatomical entity
range: anatomical entity
IAO_0000114: IAO_0000428
definition: x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to developmentally contribute to
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has potential to develop into
type: ObjectProperty
sub property of: has developmental potential involving
IAO_0000114: IAO_0000428
definition: x has the potential to develop into y iff x develops into y or if x is capable of developing into y
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: This relation has a stronger meaning than merely indicating that X may develop into Y, in that the capability of developing into Y is always present, even if X does not always actually develop into Y. In particular, this means that if Y is restricted to a given taxon T, X is necessarily likewise restricted.

has potential to directly develop into
type: ObjectProperty
sub property of: has potential to develop into
IAO_0000114: IAO_0000428
definition: x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causally related to
type: ObjectProperty
definition: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
IAO_0000116: This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yie…
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

Axiom
annotated source: causally related to
annotated property: definition
annotated target: relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
database_cross_reference: https://en.wikipedia.org/wiki/Causality

causally upstream of or within
type: ObjectProperty
sub property of: causal relation between processes
inverse of: causally downstream of or within
type: TransitiveProperty
property chain axiom: part of
definition: p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
IAO_0000116: We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000118: influences (processual)
has related synonym: affects

causally downstream of or within
type: ObjectProperty
sub property of: causal relation between processes
type: TransitiveProperty
definition: inverse of causally upstream of or within
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
in subset: RO_0002259

composed primarily of
type: ObjectProperty
sub property of: has part
domain: BFO_0000040
range: BFO_0000040
IAO_0000112: 'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'
definition: x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: http://www.ncbi.nlm.nih.gov/pubmed/22293552
RO_0001900: RO_0001901
in subset: ro-eco

receives input from
type: ObjectProperty
sub property of: connected to
inverse of: sends output to
IAO_0000116: See notes for inverse relation
IAO_0000117: https://orcid.org/0000-0002-6601-2165

sends output to
type: ObjectProperty
sub property of: connected to
IAO_0000116: This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in.
IAO_0000117: https://orcid.org/0000-0002-6601-2165

relation between physical entity and a process or stage
type: ObjectProperty
domain: BFO_0000004
range: BFO_0000003
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000232: Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage.

existence overlaps
type: ObjectProperty
sub property of: relation between physical entity and a process or stage
definition: x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))
IAO_0000117: https://orcid.org/0000-0002-6601-2165
comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.

causal agent in process
type: ObjectProperty
sub property of: causal relation between material entity and a process
inverse of: process has causal agent
definition: A relationship between a material entity and a process where the material entity has some causal role that influences the process
IAO_0000119: causal-relations

causal relation between processes
type: ObjectProperty
sub property of: causally related to
domain: BFO_0000003
range: BFO_0000003
definition: p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations
IAO_0000232: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.

depends on
type: ObjectProperty
IAO_0000117: https://orcid.org/0000-0002-6601-2165

has part structure that is capable of
type: ObjectProperty
sub property of: functionally related to
sub property of: causal relation between material entity and a process
property chain axiom: has part
property chain axiom: capable of
IAO_0000112: gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'
definition: s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
IAO_0000117: https://orcid.org/0000-0002-6601-2165

causal relation between material entity and a process
type: ObjectProperty
sub property of: causally related to
domain: BFO_0000040
range: BFO_0000015
definition: A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
IAO_0000116: Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: causal-relations

process has causal agent
type: ObjectProperty
sub property of: causally related to
definition: Inverse of 'causal agent in process'
IAO_0000119: causal-relations

generically depends on
type: ObjectProperty
inverse of: is carrier of
domain: BFO_0000031
range: BFO_0000004
property chain axiom: characteristic of
property chain axiom: is concretized as
IAO_0000112: Genetic information generically depend on molecules of DNA.
IAO_0000112: The novel *War and Peace* generically depends on this copy of the novel.
IAO_0000112: The pattern shared by chess boards generically depends on any chess board.
IAO_0000112: The score of a symphony g-depends on a copy of the score.
IAO_0000112: This pdf file generically depends on this server.
definition: A generically dependent continuant *b* generically depends on an independent continuant *c* at time *t* means: there inheres in *c* a specifically deendent continuant which concretizes *b* at *t*.
IAO_0000119: [072-ISO]
has exact synonym: g-depends on

is carrier of
type: ObjectProperty
domain: BFO_0000004
range: BFO_0000031
property chain axiom: concretizes
property chain axiom: has characteristic
IAO_0000112: Molecules of DNA are carriers of genetic information.
IAO_0000112: This copy of *War and Peace* is carrier of the novel written by Tolstoy.
IAO_0000112: This hard drive is carrier of these data items.
definition: *b* is carrier of *c* at time *t* if and only if *c* *g-depends on* *b* at *t*
IAO_0000119: [072-ISO]

has synaptic IO in region
type: ObjectProperty
sub property of: has synaptic terminal in
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:26:52Z
has exact synonym: has synaptic input or output in

receives synaptic input in region
type: ObjectProperty
sub property of: has postsynaptic terminal in
sub property of: has synaptic IO in region
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of input synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:42:23Z

sends synaptic output to region
type: ObjectProperty
sub property of: has presynaptic terminal in
sub property of: has synaptic IO in region
property chain axiom: part of
definition: A relationship between a neuron and a region, where the neuron has a functionally relevant number of output synapses in that region.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2020-07-17T09:45:06Z

receives synaptic input from neuron
type: ObjectProperty
sub property of: synapsed by
inverse of: sends synaptic output to cell
definition: A relationship between an anatomical structure (including cells) and a neuron that has a functionally relevant number of chemical synapses to it.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2021-05-26T08:40:18Z

sends synaptic output to cell
type: ObjectProperty
sub property of: synapsed to
definition: A relationship between a neuron and a cell that it has a functionally relevant number of chemical synapses to.
created by: https://orcid.org/0000-0002-1373-1705
creation date: 2021-05-26T08:41:07Z
comment: Not restricting range to 'cell' - object may be a muscle containing a cell targeted by the neuron.

synapses restricted to region
type: ObjectProperty
sub property of: has synaptic IO in region
property chain axiom: part of
IAO_0000112: An optic lobe intrinsic neuron has its synapses restricted to optic lobe neuropil.
definition: A relationship between a neuron and a region, where all of the functionally relevant input and output synapses are in that region.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-08-17T12:17:24Z
has exact synonym: intrinsic to
comment: This relation may still be used if a very small number of synapses fall slightly outside the boundaries of the region, but any class using this relation should not have another restriction using this relation to another non-overlapping region.

device utilizes material
type: ObjectProperty
property chain axiom: capable of
property chain axiom: has input
IAO_0000112: A diagnostic testing device utilizes a specimen.
definition: X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.
IAO_0000232: A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input.
IAO_0000232: See github ticket https://github.com/oborel/obo-relations/issues/497
contributor: https://orcid.org/0000-0001-9625-1899
contributor: https://orcid.org/0000-0003-2620-0345
creation date: 2021-11-08T12:00:00Z
has broad synonym: utilizes

is neuron
type: ObjectProperty
domain: CL_0000540
definition: This property only applies to neurons
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-10-23T14:34:52Z

is anatomical entity
type: ObjectProperty
domain: anatomical entity
definition: This property only applies to anatomical entities.
contributor: https://orcid.org/0000-0001-6677-8489
date: 2024-10-29T09:55:07Z

has assay method
type: ObjectProperty
sub property of: topObjectProperty
inverse of: is assay method of

is assay method of
type: ObjectProperty
sub property of: topObjectProperty

CL_0000540
type: Class
equivalent class: Restriction
  on property: is neuron
  has self: true

germ layer derivative
type: Class
equivalent class: Class
  intersection of: anatomical entity
  intersection of: Restriction
    on property: develops from
    some values from: germ layer
subclass of: anatomical entity
subclass of: Restriction
  on property: develops from
  some values from: germ layer
definition: Any anatomical entity (FBbt:10000000) that develops from some germ layer (FBbt:00000110).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000000
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: germ layer derivative
annotated property: definition
annotated target: Any anatomical entity (FBbt:10000000) that develops from some germ layer (FBbt:00000110).
database_cross_reference: FlyBase:FBrf0043441
database_cross_reference: FlyBase:FBrf0053832

organism
type: Class
subclass of: multicellular structure
definition: An individual member of the species Drosophila melanogaster.
database_cross_reference: CARO:0000012
database_cross_reference: NCBITaxon:7227
database_cross_reference: UBERON:0000468
has OBO namespace: fly_anatomy.ontology
has related synonym: Drosophila
has related synonym: whole organism
id: FBbt:00000001
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: organism
annotated property: definition
annotated target: An individual member of the species Drosophila melanogaster.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

tagma
type: Class
subclass of: anterior-posterior subdivision of organism
subclass of: Restriction
  on property: part of
  some values from: organism
definition: One of the three main divisions of the whole organism formed from groups of segments.
database_cross_reference: UBERON:6000002
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000002
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: tagma
annotated property: definition
annotated target: One of the three main divisions of the whole organism formed from groups of segments.
database_cross_reference: FBC:GG

segment
type: Class
subclass of: anterior-posterior subdivision of organism
definition: One of the repeated divisions of the whole organism.
database_cross_reference: UBERON:0000914
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000003
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: segment
annotated property: definition
annotated target: One of the repeated divisions of the whole organism.
database_cross_reference: FBC:GG

head
type: Class
subclass of: tagma
definition: Anterior part of the organism, including mouthparts, some sensory structures and the brain.
database_cross_reference: UBERON:6000004
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000004
in subset: cur
in subset: larval OF

Axiom
annotated source: head
annotated property: definition
annotated target: Anterior part of the organism, including mouthparts, some sensory structures and the brain.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

ocular segment
type: Class
subclass of: procephalic segment
definition: Head segment derived from the second embryonic segment (between the labral and antennal segments). In the larva, this segment includes Bolwig's organ.
database_cross_reference: UBERON:6000005
has OBO namespace: fly_anatomy.ontology
has related synonym: acron
id: FBbt:00000005
in subset: cur
comment: While classically this structure is not considered to be a segment, but rather to be the non-segmental acron - anterior to the first segment, this ontology follows Schmidt-Ott and colleagues (Schmidt-Ott et al., 1994, and Schmidt-Ott and Technau, 1992) in considering it to be the second segment (posterior to the labral segment in the segmenting embryo). This is based on relating gene expression in the early segmenting embryo to the effects of loss of function mutations of these genes on formation of larval head structures.

Axiom
annotated source: ocular segment
annotated property: definition
annotated target: Head segment derived from the second embryonic segment (between the labral and antennal segments). In the larva, this segment includes Bolwig's organ.
database_cross_reference: FlyBase:FBrf0055841
database_cross_reference: FlyBase:FBrf0075072

head segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: part of
    some values from: head
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: head
definition: Any segment (FBbt:00000003) that is part of some head (FBbt:00000004).
database_cross_reference: UBERON:6000006
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000006
in subset: cur
in subset: larval OF

Axiom
annotated source: head segment
annotated property: definition
annotated target: Any segment (FBbt:00000003) that is part of some head (FBbt:00000004).
database_cross_reference: FlyBase:FBrf0075072

procephalic segment
type: Class
subclass of: head segment
definition: A segment that is anterior to the gnathal segments.
database_cross_reference: UBERON:6000007
has exact synonym: pregnathal segment
has exact synonym: preoral segment
has OBO namespace: fly_anatomy.ontology
has related synonym: cephalic segment
has related synonym: procephalon
id: FBbt:00000007
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: procephalic segment
annotated property: definition
annotated target: A segment that is anterior to the gnathal segments.
database_cross_reference: FBC:GG

labral segment
type: Class
subclass of: procephalic segment
definition: Anteriormost procephalic segment, anterior to the ocular segment. In the adult it bears the clypeo-labrum.
database_cross_reference: UBERON:6000008
has OBO namespace: fly_anatomy.ontology
has related synonym: clypeo-labrum
id: FBbt:00000008
in subset: cur

Axiom
annotated source: labral segment
annotated property: definition
annotated target: Anteriormost procephalic segment, anterior to the ocular segment. In the adult it bears the clypeo-labrum.
database_cross_reference: FlyBase:FBrf0055841
database_cross_reference: FlyBase:FBrf0075072
database_cross_reference: FlyBase:FBrf0089570

antennal segment
type: Class
subclass of: procephalic segment
definition: Segment anterior to the intercalary segment. In the adult it bears the antennae.
database_cross_reference: UBERON:6000009
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000009
in subset: cur

Axiom
annotated source: antennal segment
annotated property: definition
annotated target: Segment anterior to the intercalary segment. In the adult it bears the antennae.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

intercalary segment
type: Class
subclass of: procephalic segment
definition: Most posterior of the procephalic segments. Contains the tritocerebrum.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000010
in subset: FB gloss
in subset: cur

Axiom
annotated source: intercalary segment
annotated property: definition
annotated target: Most posterior of the procephalic segments. Contains the tritocerebrum.
database_cross_reference: FlyBase:FBrf0075072
database_cross_reference: FlyBase:FBrf0089570

embryo
type: Class
subclass of: organism
definition: An organism that is undergoing embryogenesis (Campos-Ortega and Hartenstein, 1997). Embryogenesis begins with a fertilized egg, and finishes with hatching at the end of embryonic stage 17 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00005289
database_cross_reference: UBERON:0000922
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000052
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryo
annotated property: definition
annotated target: An organism that is undergoing embryogenesis (Campos-Ortega and Hartenstein, 1997). Embryogenesis begins with a fertilized egg, and finishes with hatching at the end of embryonic stage 17 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0039741
database_cross_reference: FlyBase:FBrf0089570

cleavage stage embryo
type: Class
subclass of: embryo
definition: Embryo that is in the cleavage stage, which encompasses the first 13 rapid divisions after fertilization, corresponding to embryonic stages 1-4, prior to cellularization (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). The first seven divisions are synchronous (Campos-Ortega and Hartenstein, 1997). During the course of the subsequent three divisions, most of the nuclei approach the surface, to form the syncitial blastoderm (Campos-Ortega and Hartenstein, 1997). They then divide asynchronously a further three times, bringing the total number of cells to around 5000 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00000054
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000054

Axiom
annotated source: cleavage stage embryo
annotated property: definition
annotated target: Embryo that is in the cleavage stage, which encompasses the first 13 rapid divisions after fertilization, corresponding to embryonic stages 1-4, prior to cellularization (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). The first seven divisions are synchronous (Campos-Ortega and Hartenstein, 1997). During the course of the subsequent three divisions, most of the nuclei approach the surface, to form the syncitial blastoderm (Campos-Ortega and Hartenstein, 1997). They then divide asynchronously a further three times, bringing the total number of cells to around 5000 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570

germ layer
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: portion of tissue
subclass of: Restriction
  on property: develops into
  some values from: germ layer derivative
definition: Complex primordium that is formed during gastrulation (stage 6-7), when anlagen invaginate from the monolayer of the cellular blastoderm (Campos-Ortega and Hartenstein, 1997; Hartenstein, 2004). The invaginated anlagen become organized into the middle two layers of a three-layered tube structure (Campos-Ortega and Hartenstein, 1997). These three layers correspond to the three germ layers of the endoderm, mesoderm and ectoderm (from inner to outer, respectively), with each layer having distinct cell division patterns and cell fates (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:0000923
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000110
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur

Axiom
annotated source: germ layer
annotated property: definition
annotated target: Complex primordium that is formed during gastrulation (stage 6-7), when anlagen invaginate from the monolayer of the cellular blastoderm (Campos-Ortega and Hartenstein, 1997; Hartenstein, 2004). The invaginated anlagen become organized into the middle two layers of a three-layered tube structure (Campos-Ortega and Hartenstein, 1997). These three layers correspond to the three germ layers of the endoderm, mesoderm and ectoderm (from inner to outer, respectively), with each layer having distinct cell division patterns and cell fates (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0178740

ectoderm
type: Class
subclass of: germ layer
subclass of: Restriction
  on property: develops from
  some values from: ectoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: ectodermal derivative
definition: Outermost germ layer of the embryo (Campos-Ortega and Hartenstein, 1997). It is formed from the ectoderm anlage, which includes the cells of the cellular blastoderm monolayer that do not invaginate during gastrulation (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:0000924
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000111
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur

Axiom
annotated source: ectoderm
annotated property: definition
annotated target: Outermost germ layer of the embryo (Campos-Ortega and Hartenstein, 1997). It is formed from the ectoderm anlage, which includes the cells of the cellular blastoderm monolayer that do not invaginate during gastrulation (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0244630

anterior ectoderm
type: Class
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: ectoderm
subclass of: Restriction
  on property: develops from
  some values from: anterior ectoderm anlage
definition: The region of the ectoderm anterior to the cephalic furrow.
database_cross_reference: UBERON:6000119
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000119
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: anterior ectoderm
annotated property: definition
annotated target: The region of the ectoderm anterior to the cephalic furrow.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic tagma
type: Class
equivalent class: Class
  intersection of: tagma
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: tagma
subclass of: Restriction
  on property: part of
  some values from: embryo
definition: Any tagma of the embryo.
database_cross_reference: UBERON:6000137
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000137
in subset: cur

Axiom
annotated source: embryonic tagma
annotated property: definition
annotated target: Any tagma of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: embryo
definition: Any segment of the embryo.
database_cross_reference: UBERON:6000154
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000154
in subset: cur

Axiom
annotated source: embryonic segment
annotated property: definition
annotated target: Any segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic head
type: Class
equivalent class: Class
  intersection of: head
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: head
subclass of: embryonic tagma
definition: Any head of the embryo.
database_cross_reference: UBERON:0008816
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000155
in subset: cur
in subset: larval OF

Axiom
annotated source: embryonic head
annotated property: definition
annotated target: Any head of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic ocular segment
type: Class
equivalent class: Class
  intersection of: ocular segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: ocular segment
subclass of: embryonic procephalic segment
definition: Any ocular segment of the embryo.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic acron
id: FBbt:00000156
in subset: cur

Axiom
annotated source: embryonic ocular segment
annotated property: definition
annotated target: Any ocular segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic head segment
type: Class
equivalent class: Class
  intersection of: head segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: head segment
subclass of: embryonic segment
subclass of: Restriction
  on property: part of
  some values from: embryonic head
definition: Any head segment of the embryo.
database_cross_reference: UBERON:6000157
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000157
in subset: cur

Axiom
annotated source: embryonic head segment
annotated property: definition
annotated target: Any head segment of the embryo.
database_cross_reference: FlyBase:FBrf0075072

embryonic procephalic segment
type: Class
equivalent class: Class
  intersection of: procephalic segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: procephalic segment
subclass of: embryonic head segment
definition: Any procephalic segment of the embryo.
database_cross_reference: UBERON:6000158
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000158
in subset: cur

Axiom
annotated source: embryonic procephalic segment
annotated property: definition
annotated target: Any procephalic segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic labral segment
type: Class
equivalent class: Class
  intersection of: labral segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: labral segment
subclass of: embryonic procephalic segment
definition: Any labral segment of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000159
in subset: cur

Axiom
annotated source: embryonic labral segment
annotated property: definition
annotated target: Any labral segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic antennal segment
type: Class
equivalent class: Class
  intersection of: antennal segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: antennal segment
subclass of: embryonic procephalic segment
definition: Any antennal segment of the embryo.
database_cross_reference: UBERON:6000160
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000160
in subset: cur

Axiom
annotated source: embryonic antennal segment
annotated property: definition
annotated target: Any antennal segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic intercalary segment
type: Class
equivalent class: Class
  intersection of: intercalary segment
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: intercalary segment
subclass of: embryonic procephalic segment
definition: Any intercalary segment of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000161
in subset: cur

Axiom
annotated source: embryonic intercalary segment
annotated property: definition
annotated target: Any intercalary segment of the embryo.
database_cross_reference: FBC:Autogenerated

embryonic optic lobe primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: larval optic anlage
definition: Primordium of the late extended germ band and closure embryo that gives rise to the embryonic/larval optic anlage. It corresponds to the middle region that develops from the visual primordium.
database_cross_reference: UBERON:6000186
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000186
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic optic lobe primordium
annotated property: definition
annotated target: Primordium of the late extended germ band and closure embryo that gives rise to the embryonic/larval optic anlage. It corresponds to the middle region that develops from the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic inner optic lobe primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic optic lobe primordium
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: larval inner optic anlage
definition: Primordium of the late extended germ band and closure embryo that gives rise to the larval inner optic anlage. It develops from the anterior lip of the visual primordium.
has exact synonym: P1 IOA
has OBO namespace: fly_anatomy.ontology
id: FBbt:00000461
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic inner optic lobe primordium
annotated property: definition
annotated target: Primordium of the late extended germ band and closure embryo that gives rise to the larval inner optic anlage. It develops from the anterior lip of the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: embryonic inner optic lobe primordium
annotated property: hasExactSynonym
annotated target: P1 IOA
database_cross_reference: https://orcid.org/0000-0002-7073-9172

larval apodeme
type: Class
equivalent class: Class
  intersection of: apodeme
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: apodeme
subclass of: Restriction
  on property: part of
  some values from: larval integumentary system
definition: Apodeme that is part of the late embryo/larva. Apodemes are not a continuous structure, but are split into two halves. In the embryo, this break is visible laterally. In the larva, the dorsal and ventral halves in the thoracic and abdominal segments are staggered, with the dorsal part being posterior to the ventral one.
has exact synonym: embryonic/larval apodeme
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001005
in subset: cur

Axiom
annotated source: larval apodeme
annotated property: definition
annotated target: Apodeme that is part of the late embryo/larva. Apodemes are not a continuous structure, but are split into two halves. In the embryo, this break is visible laterally. In the larva, the dorsal and ventral halves in the thoracic and abdominal segments are staggered, with the dorsal part being posterior to the ventral one.
database_cross_reference: FBC:SPR
database_cross_reference: FlyBase:FBrf0089570

presumptive embryonic/larval nervous system
type: Class
subclass of: presumptive embryonic/larval system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval nervous system.
database_cross_reference: UBERON:6001055
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic nervous system
id: FBbt:00001055
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: presumptive embryonic/larval nervous system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval nervous system.
database_cross_reference: FlyBase:FBrf0031012

Axiom
annotated source: presumptive embryonic/larval nervous system
annotated property: hasRelatedSynonym
annotated target: embryonic nervous system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

presumptive embryonic/larval central nervous system
type: Class
subclass of: presumptive embryonic/larval system
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval nervous system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval central nervous system.
database_cross_reference: UBERON:6001056
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic central nervous system
id: FBbt:00001056
in subset: cur

Axiom
annotated source: presumptive embryonic/larval central nervous system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval central nervous system.
database_cross_reference: FlyBase:FBrf0031012

Axiom
annotated source: presumptive embryonic/larval central nervous system
annotated property: hasRelatedSynonym
annotated target: embryonic central nervous system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

neurogenic region
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: ectoderm
definition: Region that gives rise to the neuroblasts of the central nervous system (Bossing et al., 1996). An anterior region (procephalic neurogenic region) gives rise to the brain and a posterior, ventral region (ventral neuroectoderm) gives rise to the ventral nerve cord and gnathal ganglia (Bossing et al., 1996).
database_cross_reference: UBERON:0002346
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001057
in subset: cur

Axiom
annotated source: neurogenic region
annotated property: definition
annotated target: Region that gives rise to the neuroblasts of the central nervous system (Bossing et al., 1996). An anterior region (procephalic neurogenic region) gives rise to the brain and a posterior, ventral region (ventral neuroectoderm) gives rise to the ventral nerve cord and gnathal ganglia (Bossing et al., 1996).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0090460
database_cross_reference: FlyBase:FBrf0098344

procephalic neurogenic region
type: Class
subclass of: neurogenic region
subclass of: Restriction
  on property: part of
  some values from: anterior ectoderm
subclass of: Restriction
  on property: part of
  some values from: embryonic head
definition: Tissue which becomes morphologically distinct shortly after cephalic furrow formation as two strips of about 80 enlarged cells which extend dorso-ventrally on either side of the developing head. It gives rise to neuroblasts of the brain.
has exact synonym: pregnathal neuroectoderm
has exact synonym: procephalic neuroectoderm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001058
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: procephalic neurogenic region
annotated property: definition
annotated target: Tissue which becomes morphologically distinct shortly after cephalic furrow formation as two strips of about 80 enlarged cells which extend dorso-ventrally on either side of the developing head. It gives rise to neuroblasts of the brain.
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0090460

Axiom
annotated source: procephalic neurogenic region
annotated property: hasExactSynonym
annotated target: pregnathal neuroectoderm
database_cross_reference: FlyBase:FBrf0161020

Axiom
annotated source: procephalic neurogenic region
annotated property: hasExactSynonym
annotated target: procephalic neuroectoderm
database_cross_reference: FlyBase:FBrf0161020

visual primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: anterior ectoderm derivative
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: embryonic optic lobe primordium
  intersection of: Restriction
    on property: develops into
    some values from: early embryonic primordium of adult eye
  intersection of: Restriction
    on property: develops into
    some values from: Bolwig organ primordium
subclass of: Restriction
  on property: part of
  some values from: early extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: visual anlage
definition: Primordium that develops from the posterior procephalic region of the embryo and gives rise to visual structures of the larva and adult (Green et al., 1993; Chang et al., 2001). An optic placode forms from cells of the visual primordium when they become columnar in shape towards the end of stage 11 (Green et al., 1993; Chang et al., 2001). This placode invaginates during stages 12-13, forming a deep pouch of approximately 85 cells (Green et al., 1993). Its ventral lip segregates from the rest of the primordium and develops into the Bolwig organ (Green et al., 1993). The remainder of the placode, which will form the optic lobe, detaches from the surface of the embryo and attaches to the lateral brain, maintaining a tubular appearance until larval hatching (Green et al., 1993). Its anterior and posterior domains will become the larval inner and outer optic anlage, respectively (Chang et al., 2001). The cells that will become the eye disc are anterior and dorsal to the optic lobe placode cells (Chang et al., 2001). They move into the interior of the embryo during head involution, when they are pushed under the dorsal ridge (Huang et al., 2017).
database_cross_reference: UBERON:6001059
has narrow synonym: optic lobe placode
has narrow synonym: optic lobe primordium
has OBO namespace: fly_anatomy.ontology
has related synonym: P2 VisSys
id: FBbt:00001059
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: visual primordium
annotated property: definition
annotated target: Primordium that develops from the posterior procephalic region of the embryo and gives rise to visual structures of the larva and adult (Green et al., 1993; Chang et al., 2001). An optic placode forms from cells of the visual primordium when they become columnar in shape towards the end of stage 11 (Green et al., 1993; Chang et al., 2001). This placode invaginates during stages 12-13, forming a deep pouch of approximately 85 cells (Green et al., 1993). Its ventral lip segregates from the rest of the primordium and develops into the Bolwig organ (Green et al., 1993). The remainder of the placode, which will form the optic lobe, detaches from the surface of the embryo and attaches to the lateral brain, maintaining a tubular appearance until larval hatching (Green et al., 1993). Its anterior and posterior domains will become the larval inner and outer optic anlage, respectively (Chang et al., 2001). The cells that will become the eye disc are anterior and dorsal to the optic lobe placode cells (Chang et al., 2001). They move into the interior of the embryo during head involution, when they are pushed under the dorsal ridge (Huang et al., 2017).
database_cross_reference: FlyBase:FBrf0064481
database_cross_reference: FlyBase:FBrf0141490
database_cross_reference: FlyBase:FBrf0235170
database_cross_reference: FlyBase:FBrf0243080

Axiom
annotated source: visual primordium
annotated property: hasNarrowSynonym
annotated target: optic lobe placode
database_cross_reference: FlyBase:FBrf0141490

Axiom
annotated source: visual primordium
annotated property: hasRelatedSynonym
annotated target: P2 VisSys
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic brain
type: Class
subclass of: supraesophageal ganglion
subclass of: brain
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval central nervous system
subclass of: Restriction
  on property: develops from
  some values from: procephalic neurogenic region
definition: Brain of the embryo, consisting of the protocerebrum, deutocerebrum and tritocerebrum (Urbach and Technau, 2003; Crews, 2019). It develops from the procephalic neurogenic region (Urbach and Technau, 2003).
database_cross_reference: UBERON:6001060
database_cross_reference: VFB:FBbt_00001060
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001060
in subset: cur

Axiom
annotated source: embryonic brain
annotated property: definition
annotated target: Brain of the embryo, consisting of the protocerebrum, deutocerebrum and tritocerebrum (Urbach and Technau, 2003; Crews, 2019). It develops from the procephalic neurogenic region (Urbach and Technau, 2003).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0244240

ventral neurectoderm
type: Class
subclass of: neurogenic region
subclass of: epithelium
subclass of: Restriction
  on property: part of
  some values from: ventral ectoderm
definition: The ventrally/medially located ectodermal region of the trunk from which neuroblasts delaminate to form the ventral nerve cord and gnathal ganglia. This region becomes distinct during stage 8 when its cells become enlarged compared to those in the adjacent dorsal ectoderm.
has alternative id: FBbt:00000113
has exact synonym: P2 VenEc
has exact synonym: VenEc
has exact synonym: vNR
has exact synonym: ventral neurogenic region
has OBO namespace: fly_anatomy.ontology
has related synonym: neurectoderm
has related synonym: neuroectoderm
id: FBbt:00001061
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral neurectoderm
annotated property: definition
annotated target: The ventrally/medially located ectodermal region of the trunk from which neuroblasts delaminate to form the ventral nerve cord and gnathal ganglia. This region becomes distinct during stage 8 when its cells become enlarged compared to those in the adjacent dorsal ectoderm.
database_cross_reference: FlyBase:FBrf0076117
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: ventral neurectoderm
annotated property: hasExactSynonym
annotated target: vNR
database_cross_reference: FlyBase:FBrf0090460

Axiom
annotated source: ventral neurectoderm
annotated property: hasExactSynonym
annotated target: ventral neurogenic region
database_cross_reference: FlyBase:FBrf0090460

proneural cluster
type: Class
subclass of: anlage
definition: An equivalence group of the neurectoderm where all cells can, although only one will, become a neural progenitor cell.
database_cross_reference: UBERON:6001135
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001135
in subset: cur

Axiom
annotated source: proneural cluster
annotated property: definition
annotated target: An equivalence group of the neurectoderm where all cells can, although only one will, become a neural progenitor cell.
database_cross_reference: FlyBase:FBrf0074477
database_cross_reference: FlyBase:FBrf0089570

sensory mother cell
type: Class
subclass of: peripheral sensory precursor cell
subclass of: Restriction
  on property: part of
  some values from: proneural cluster
definition: Precursor cell that can give rise to all the neuronal and support cells that form a peripheral sense organ.
has exact synonym: SMC
has exact synonym: SOP
has exact synonym: sensory organ precursor cell
has exact synonym: sensory organ progenitor cell
has OBO namespace: fly_anatomy.ontology
has related synonym: sensillum precursor
has related synonym: sensory organ mother cell
id: FBbt:00001137
in subset: cur

Axiom
annotated source: sensory mother cell
annotated property: definition
annotated target: Precursor cell that can give rise to all the neuronal and support cells that form a peripheral sense organ.
database_cross_reference: FlyBase:FBrf0055951
database_cross_reference: FlyBase:FBrf0083795
database_cross_reference: FlyBase:FBrf0132424

Axiom
annotated source: sensory mother cell
annotated property: hasExactSynonym
annotated target: SMC
database_cross_reference: FlyBase:FBrf0055951

Axiom
annotated source: sensory mother cell
annotated property: hasExactSynonym
annotated target: SOP
database_cross_reference: FlyBase:FBrf0132424

Axiom
annotated source: sensory mother cell
annotated property: hasExactSynonym
annotated target: sensory organ precursor cell
database_cross_reference: FlyBase:FBrf0132424

Axiom
annotated source: sensory mother cell
annotated property: hasExactSynonym
annotated target: sensory organ progenitor cell
database_cross_reference: FlyBase:FBrf0132424

embryonic glioblast
type: Class
equivalent class: Class
  intersection of: glioblast
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: embryonic neuroblast
subclass of: glioblast
definition: Glioblast of the embryo.
database_cross_reference: VFB:FBbt_00001244
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001244
in subset: cur

Axiom
annotated source: embryonic glioblast
annotated property: definition
annotated target: Glioblast of the embryo.
database_cross_reference: FlyBase:FBrf0105240

larval glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: glial cell
subclass of: Restriction
  on property: part of
  some values from: larval nervous system
definition: Glial cell of the late embryo/larva.
database_cross_reference: VFB:FBbt_00001251
has exact synonym: embryonic/larval glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001251
in subset: cur

Axiom
annotated source: larval glial cell
annotated property: definition
annotated target: Glial cell of the late embryo/larva.
database_cross_reference: FlyBase:FBrf0050373
database_cross_reference: FlyBase:FBrf0053160
database_cross_reference: FlyBase:FBrf0054242
database_cross_reference: FlyBase:FBrf0090460
database_cross_reference: FlyBase:FBrf0098344
database_cross_reference: FlyBase:FBrf0105240
database_cross_reference: FlyBase:FBrf0205499
database_cross_reference: FlyBase:FBrf0214261

CNS glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: central nervous system
subclass of: glial cell
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Glial cell of the central nervous system.
database_cross_reference: VFB:FBbt_00001256
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001256
in subset: cur

Axiom
annotated source: CNS glial cell
annotated property: definition
annotated target: Glial cell of the central nervous system.
database_cross_reference: FlyBase:FBrf0206543

cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: cell body rind of the central nervous system
subclass of: CNS glial cell
subclass of: Restriction
  on property: part of
  some values from: cell body rind of the central nervous system
definition: Glial cell with a nucleus amongst the neuronal cell bodies in the cell body rind. It is irregularly shaped, with processes that enclose the neuronal cell bodies.
database_cross_reference: VFB:FBbt_00001297
has exact synonym: CBG
has exact synonym: cell body-associated glial cell
has exact synonym: cortex associated CNS glial cell
has exact synonym: cortex glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001297
in subset: cur
comment: Glial cells associated with axonal tracts (such as those associated with nerve roots) are excluded from this class of glial cells (Ito et al., 1995). Modeled as 'part of' their 'cell body rind' regions, though in practice some cell body glia have small projections into the neuropil - https://orcid.org/0000-0002-1373-1705.

Axiom
annotated source: cell body glial cell
annotated property: definition
annotated target: Glial cell with a nucleus amongst the neuronal cell bodies in the cell body rind. It is irregularly shaped, with processes that enclose the neuronal cell bodies.
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: cell body glial cell
annotated property: hasExactSynonym
annotated target: CBG
database_cross_reference: FlyBase:FBrf0082171

Axiom
annotated source: cell body glial cell
annotated property: hasExactSynonym
annotated target: cell body-associated glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: cell body glial cell
annotated property: hasExactSynonym
annotated target: cortex glial cell
database_cross_reference: FlyBase:FBrf0214261

embryonic/larval cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: cell body rind of larval central nervous system
subclass of: cell body glial cell
subclass of: embryonic/larval lateral glial cell
subclass of: Restriction
  on property: part of
  some values from: cell body rind of larval central nervous system
definition: Glial cell located amongst neuronal cell bodies in the cell body rind of the embryonic/larval central nervous system.
database_cross_reference: VFB:FBbt_00001298
has exact synonym: embryonic/larval cortex glial cell
has exact synonym: larval CBG
has OBO namespace: fly_anatomy.ontology
has related synonym: CoG
id: FBbt:00001298
in subset: cur

Axiom
annotated source: embryonic/larval cell body glial cell
annotated property: definition
annotated target: Glial cell located amongst neuronal cell bodies in the cell body rind of the embryonic/larval central nervous system.
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0237238

Axiom
annotated source: embryonic/larval cell body glial cell
annotated property: hasExactSynonym
annotated target: embryonic/larval cortex glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: embryonic/larval cell body glial cell
annotated property: hasExactSynonym
annotated target: larval CBG
database_cross_reference: FlyBase:FBrf0082171

neuropil glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: neuropil glial sheath
subclass of: CNS glial cell
subclass of: Restriction
  on property: overlaps
  some values from: neuropil glial sheath
definition: Glial cell of the CNS that is associated with neuropil compartments, including synaptic and tract neuropil (Hartenstein, 2011; Omoto et al., 2015; Kremer et al., 2017). These cells have their cell bodies located in the neuropil glial sheath, between the neuropil and the cell body rind, and many of them extend processes into the neuropil (Hartenstein, 2011; Omoto et al., 2015). Two subtypes have been identified, the reticular (astrocyte-like) and ensheathing glia (Hartenstein, 2011; Omoto et al., 2015), which both function in ionic and neurotransmitter homeostasis (Kremer et al., 2017).
database_cross_reference: VFB:FBbt_00001303
has exact synonym: neuropil associated CNS glial cell
has exact synonym: neuropil associated glial cell
has exact synonym: neuropil-associated CNS glial cell
has exact synonym: neuropil-associated glial cell
has exact synonym: neuropile glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001303
in subset: cur

Axiom
annotated source: neuropil glial cell
annotated property: definition
annotated target: Glial cell of the CNS that is associated with neuropil compartments, including synaptic and tract neuropil (Hartenstein, 2011; Omoto et al., 2015; Kremer et al., 2017). These cells have their cell bodies located in the neuropil glial sheath, between the neuropil and the cell body rind, and many of them extend processes into the neuropil (Hartenstein, 2011; Omoto et al., 2015). Two subtypes have been identified, the reticular (astrocyte-like) and ensheathing glia (Hartenstein, 2011; Omoto et al., 2015), which both function in ionic and neurotransmitter homeostasis (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0082171
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0229106
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: neuropil glial cell
annotated property: hasExactSynonym
annotated target: neuropil associated glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: neuropil glial cell
annotated property: hasExactSynonym
annotated target: neuropil-associated glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: neuropil glial cell
annotated property: hasExactSynonym
annotated target: neuropile glial cell
database_cross_reference: FlyBase:FBrf0214261

PNS glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: peripheral nervous system
subclass of: glial cell
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
definition: Glial cell that is part of the peripheral nervous system.
database_cross_reference: VFB:FBbt_00001320
has exact synonym: peripheral glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001320
in subset: cur

Axiom
annotated source: PNS glial cell
annotated property: definition
annotated target: Glial cell that is part of the peripheral nervous system.
database_cross_reference: FBC:SPR

embryonic neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: developing embryonic structure
subclass of: neuroblast
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval nervous system
definition: Any neuroblast of the embryo.
database_cross_reference: VFB:FBbt_00001332
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001332
in subset: cur

Axiom
annotated source: embryonic neuroblast
annotated property: definition
annotated target: Any neuroblast of the embryo.
database_cross_reference: FlyBase:FBrf0055900

procephalic neuroblast
type: Class
subclass of: neuroblast
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: develops from
  some values from: procephalic neurogenic region
definition: Neuroblast of one of the three procephalic regions, protocerebrum, deutocerebrum and tritocerebrum, which form the supraesophageal ganglion of the brain (Urbach et al., 2003). These neuroblasts derive from the procephalic neurogenic region (Urbach et al., 2003).
database_cross_reference: VFB:FBbt_00001333
has exact synonym: neuroblast of supraesophageal ganglion
has narrow synonym: brain neuroblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001333
in subset: cur

Axiom
annotated source: procephalic neuroblast
annotated property: definition
annotated target: Neuroblast of one of the three procephalic regions, protocerebrum, deutocerebrum and tritocerebrum, which form the supraesophageal ganglion of the brain (Urbach et al., 2003). These neuroblasts derive from the procephalic neurogenic region (Urbach et al., 2003).
database_cross_reference: FlyBase:FBrf0161021

protocerebral neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: part of
    some values from: protocerebrum
subclass of: procephalic neuroblast
subclass of: Restriction
  on property: part of
  some values from: protocerebrum
definition: A neuroblast located in the protocerebrum. None of these are serial homologues of neuroblasts found in the thoracic neuromeres (Urbach et al., 2016).
database_cross_reference: VFB:FBbt_00001334
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001334
in subset: cur
comment: In the embryo, individual neuroblasts are named according to their position relative to major morphological features (cephalic furrow, invaginating foregut, dorsal and ventral midline, their relative position with respect to each other, their time of segregation and their expression of markers) (Urbach et al., 2003).

Axiom
annotated source: protocerebral neuroblast
annotated property: definition
annotated target: A neuroblast located in the protocerebrum. None of these are serial homologues of neuroblasts found in the thoracic neuromeres (Urbach et al., 2016).
database_cross_reference: FlyBase:FBrf0089217
database_cross_reference: FlyBase:FBrf0161021
database_cross_reference: FlyBase:FBrf0232096

deutocerebral neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: part of
    some values from: deutocerebrum
subclass of: procephalic neuroblast
subclass of: Restriction
  on property: part of
  some values from: deutocerebrum
definition: A neuroblast located in the deutocerebrum. Some of these are serial homologues of neuroblasts found in the thoracic neuromeres (Urbach et al., 2016).
database_cross_reference: VFB:FBbt_00001353
has exact synonym: deuterocerebral neuroblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001353
in subset: cur
comment: In the embryo, individual neuroblasts are named according to their position relative to major morphological features (cephalic furrow, invaginating foregut, dorsal and ventral midline, their relative position with respect to each other, their time of segregation and their expression of markers) (Urbach et al., 2003).

Axiom
annotated source: deutocerebral neuroblast
annotated property: definition
annotated target: A neuroblast located in the deutocerebrum. Some of these are serial homologues of neuroblasts found in the thoracic neuromeres (Urbach et al., 2016).
database_cross_reference: FlyBase:FBrf0089217
database_cross_reference: FlyBase:FBrf0161021
database_cross_reference: FlyBase:FBrf0232096

tritocerebral neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: part of
    some values from: tritocerebrum
subclass of: procephalic neuroblast
subclass of: Restriction
  on property: part of
  some values from: tritocerebrum
definition: A neuroblast located in the tritocerebrum. Most, if not all, of these have serial homology to neuroblasts found in the thoracic neuromeres (Urbach et al., 2016). There are 13 of these, of which four produce a secondary lineage (Kuert et al., 2012; Urbach et al., 2016).
database_cross_reference: VFB:FBbt_00001363
has OBO namespace: fly_anatomy.ontology
has related synonym: T
id: FBbt:00001363
in subset: cur
comment: In the embryo, individual neuroblasts are named according to their position relative to major morphological features (cephalic furrow, invaginating foregut, dorsal and ventral midline, their relative position with respect to each other, their time of segregation and their expression of markers) (Urbach et al., 2003).

Axiom
annotated source: tritocerebral neuroblast
annotated property: definition
annotated target: A neuroblast located in the tritocerebrum. Most, if not all, of these have serial homology to neuroblasts found in the thoracic neuromeres (Urbach et al., 2016). There are 13 of these, of which four produce a secondary lineage (Kuert et al., 2012; Urbach et al., 2016).
database_cross_reference: FlyBase:FBrf0089217
database_cross_reference: FlyBase:FBrf0161021
database_cross_reference: FlyBase:FBrf0220148
database_cross_reference: FlyBase:FBrf0232096

supraesophageal ganglion neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: supraesophageal ganglion
subclass of: CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: supraesophageal ganglion
definition: Any neuron (FBbt:00005106) that has its soma located in some supraesophageal ganglion (FBbt:00003626).
database_cross_reference: VFB:FBbt_00001366
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001366
in subset: cur

Axiom
annotated source: supraesophageal ganglion neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some supraesophageal ganglion (FBbt:00003626).
database_cross_reference: FBC:Autogenerated

larval neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: larval nervous system
definition: Neuron that is part of the larval nervous system. Neurons with functional roles in the larva are born during the embryonic phase of neurogenesis and further neurons, with adult-specific roles, are born during the postembryonic phase, which begins during larval development (Lacin and Truman, 2016).
database_cross_reference: VFB:FBbt_00001446
has exact synonym: embryonic/larval neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001446
in subset: cur
comment: This includes immature secondary neurons that are found in the larva - https://orcid.org/0000-0002-1373-1705.

Axiom
annotated source: larval neuron
annotated property: definition
annotated target: Neuron that is part of the larval nervous system. Neurons with functional roles in the larva are born during the embryonic phase of neurogenesis and further neurons, with adult-specific roles, are born during the postembryonic phase, which begins during larval development (Lacin and Truman, 2016).
database_cross_reference: FlyBase:FBrf0090460
database_cross_reference: FlyBase:FBrf0098344
database_cross_reference: FlyBase:FBrf0231327

embryonic imaginal tissue
type: Class
equivalent class: Class
  intersection of: imaginal tissue
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: developing embryonic structure
subclass of: imaginal tissue
definition: Embryonic structure that will develop into a larval imaginal tissue, which will later form an adult structure (Cohen, 1993).
database_cross_reference: UBERON:6001648
has exact synonym: embryonic imaginal precursor
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001648
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic imaginal tissue
annotated property: definition
annotated target: Embryonic structure that will develop into a larval imaginal tissue, which will later form an adult structure (Cohen, 1993).
database_cross_reference: FlyBase:FBrf0064789

imaginal disc primordium
type: Class
subclass of: embryonic imaginal tissue
subclass of: primordium
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral epidermis primordium
subclass of: Restriction
  on property: develops into
  some values from: imaginal disc
definition: Population of contiguous, morphologically distinct cells of the embryo that will proliferate to form an imaginal disc in the larva. During early embryogenesis the precursor is part of the epithelial sheet before segregating from the epithelial sheet by late embryogenesis (Cohen, 1993).
database_cross_reference: UBERON:6001649
has OBO namespace: fly_anatomy.ontology
has related synonym: imaginal disc specific anlage
id: FBbt:00001649
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: imaginal disc primordium
annotated property: definition
annotated target: Population of contiguous, morphologically distinct cells of the embryo that will proliferate to form an imaginal disc in the larva. During early embryogenesis the precursor is part of the epithelial sheet before segregating from the epithelial sheet by late embryogenesis (Cohen, 1993).
database_cross_reference: FBC:SPR
database_cross_reference: FlyBase:FBrf0064789

eye-antennal disc primordium
type: Class
subclass of: imaginal disc primordium
subclass of: Restriction
  on property: part of
  some values from: embryonic antennal segment
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops into
  some values from: eye-antennal disc
definition: Primordium from which the eye-antennal disc develops.
database_cross_reference: UBERON:6001652
has OBO namespace: fly_anatomy.ontology
has related synonym: eye-antennal disc specific anlage
id: FBbt:00001652
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: eye-antennal disc primordium
annotated property: definition
annotated target: Primordium from which the eye-antennal disc develops.
database_cross_reference: FBC:SPR

larva
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: embryo
definition: Organism during the period between hatching and prepupa formation.
database_cross_reference: UBERON:0002548
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001727
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: larva
annotated property: definition
annotated target: Organism during the period between hatching and prepupa formation.
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0089570

larval tagma
type: Class
equivalent class: Class
  intersection of: tagma
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: tagma
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Any tagma of the larva.
database_cross_reference: UBERON:6001728
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001728
in subset: cur

Axiom
annotated source: larval tagma
annotated property: definition
annotated target: Any tagma of the larva.
database_cross_reference: FBC:Autogenerated

larval segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: larva
subclass of: Restriction
  on property: develops from
  some values from: embryonic segment
definition: Any segment of the larva.
database_cross_reference: UBERON:6001729
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001729
in subset: cur
in subset: larval OF

Axiom
annotated source: larval segment
annotated property: definition
annotated target: Any segment of the larva.
database_cross_reference: FBC:Autogenerated

larval head
type: Class
equivalent class: Class
  intersection of: head
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: head
subclass of: larval tagma
definition: Any head of the larva.
database_cross_reference: UBERON:6001730
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001730
in subset: cur
in subset: larval OF

Axiom
annotated source: larval head
annotated property: definition
annotated target: Any head of the larva.
database_cross_reference: FBC:Autogenerated

larval ocular segment
type: Class
equivalent class: Class
  intersection of: ocular segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: ocular segment
subclass of: larval procephalic segment
definition: Any ocular segment of the larva.
database_cross_reference: UBERON:6001731
has OBO namespace: fly_anatomy.ontology
has related synonym: larval acron
id: FBbt:00001731
in subset: cur

Axiom
annotated source: larval ocular segment
annotated property: definition
annotated target: Any ocular segment of the larva.
database_cross_reference: FBC:Autogenerated

larval head segment
type: Class
equivalent class: Class
  intersection of: head segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: head segment
subclass of: larval segment
subclass of: Restriction
  on property: part of
  some values from: larval head
definition: Any head segment of the larva.
database_cross_reference: UBERON:6001732
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001732
in subset: cur
in subset: larval OF

Axiom
annotated source: larval head segment
annotated property: definition
annotated target: Any head segment of the larva.
database_cross_reference: FlyBase:FBrf0075072

larval procephalic segment
type: Class
equivalent class: Class
  intersection of: procephalic segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: procephalic segment
subclass of: larval head segment
definition: Any procephalic segment of the larva.
database_cross_reference: UBERON:6001733
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001733
in subset: cur
in subset: larval OF

Axiom
annotated source: larval procephalic segment
annotated property: definition
annotated target: Any procephalic segment of the larva.
database_cross_reference: FBC:Autogenerated

larval labral segment
type: Class
equivalent class: Class
  intersection of: labral segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: labral segment
subclass of: larval procephalic segment
definition: Any labral segment of the larva.
database_cross_reference: UBERON:6001734
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001734
in subset: cur
in subset: larval OF

Axiom
annotated source: larval labral segment
annotated property: definition
annotated target: Any labral segment of the larva.
database_cross_reference: FBC:Autogenerated

larval antennal segment
type: Class
equivalent class: Class
  intersection of: antennal segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: antennal segment
subclass of: larval procephalic segment
definition: Any antennal segment of the larva.
database_cross_reference: UBERON:6001735
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001735
in subset: cur
in subset: larval OF

Axiom
annotated source: larval antennal segment
annotated property: definition
annotated target: Any antennal segment of the larva.
database_cross_reference: FBC:Autogenerated

larval intercalary segment
type: Class
equivalent class: Class
  intersection of: intercalary segment
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: intercalary segment
subclass of: larval procephalic segment
definition: Any intercalary segment of the larva.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001736
in subset: cur

Axiom
annotated source: larval intercalary segment
annotated property: definition
annotated target: Any intercalary segment of the larva.
database_cross_reference: FBC:Autogenerated

larval imaginal tissue
type: Class
equivalent class: Class
  intersection of: imaginal tissue
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: imaginal tissue
subclass of: Restriction
  on property: part of
  some values from: larva
subclass of: Restriction
  on property: develops from
  some values from: embryonic imaginal tissue
definition: Imaginal tissue that is found in the larva and will develop into an adult structure during metamorphosis.
database_cross_reference: UBERON:6001760
has exact synonym: embryonic/larval imaginal precursor
has exact synonym: larval imaginal precursor
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001760
in subset: cur

Axiom
annotated source: larval imaginal tissue
annotated property: definition
annotated target: Imaginal tissue that is found in the larva and will develop into an adult structure during metamorphosis.
database_cross_reference: FlyBase:FBrf0064789

imaginal disc
type: Class
subclass of: larval imaginal tissue
subclass of: multi-tissue structure
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: develops from
  some values from: imaginal disc primordium
definition: A sac shaped epithelial structure in the larva that gives rise to part of the adult integumentary system. One side of the sac consists of peripodial epithelium, the other of columnar epithelium. A single anterior-posterior compartment boundary bisects both peripodial membrane and columnar epithelium. Cells do not cross this boundary during growth and development of the disc.
database_cross_reference: UBERON:0000939
has OBO namespace: fly_anatomy.ontology
has related synonym: imaginal disk
id: FBbt:00001761
in subset: FB gloss
in subset: cur

Axiom
annotated source: imaginal disc
annotated property: definition
annotated target: A sac shaped epithelial structure in the larva that gives rise to part of the adult integumentary system. One side of the sac consists of peripodial epithelium, the other of columnar epithelium. A single anterior-posterior compartment boundary bisects both peripodial membrane and columnar epithelium. Cells do not cross this boundary during growth and development of the disc.
database_cross_reference: FBC:GG

eye-antennal disc
type: Class
subclass of: imaginal disc
subclass of: Restriction
  on property: develops from
  some values from: eye-antennal disc primordium
definition: Imaginal disc that, in the adults, gives rise to the eye, antenna, head capsule (including all bristles and external membranes) and the maxillary palps (Cohen, 1993).
database_cross_reference: UBERON:6001766
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001766
in subset: EmbDevSlim
in subset: cur
comment: Figure 12 from Cohen (1993, Bate, Martinez Arias, 1993: 747--841) provides a fate map of the eye-antennal disc.

Axiom
annotated source: eye-antennal disc
annotated property: definition
annotated target: Imaginal disc that, in the adults, gives rise to the eye, antenna, head capsule (including all bristles and external membranes) and the maxillary palps (Cohen, 1993).
database_cross_reference: FlyBase:FBrf0064789

eye disc
type: Class
subclass of: imaginal disc
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: eye-antennal disc
subclass of: Restriction
  on property: develops from
  some values from: late embryonic primordium of adult eye
definition: Anterior, bulbous portion of the eye-antennal disc that gives rise to the eye as well as contributing to the head capsule (Cohen, 1993).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001768
in subset: cur
comment: Figure 12 from Cohen (1993, Bate, Martinez Arias, 1993: 747--841) provides a fate map of the eye-antennal disc.

Axiom
annotated source: eye disc
annotated property: definition
annotated target: Anterior, bulbous portion of the eye-antennal disc that gives rise to the eye as well as contributing to the head capsule (Cohen, 1993).
database_cross_reference: FlyBase:FBrf0064789

ommatidial precursor cluster
type: Class
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: eye disc posterior to the morphogenetic furrow
subclass of: Restriction
  on property: develops into
  some values from: ommatidium
definition: A cluster of cells in the eye-disc that is the precursor to an adult ommatidium. Eventually there are approximately 750 ommatidial precursor clusters per eye-disc, the first forming at approximately 70hrs before pupation along the morphogenic furrow. A new row of adult ommatidial precursors then emerges from the morphogenic furrow roughly every 1.5 hours.
has OBO namespace: fly_anatomy.ontology
has related synonym: ommatidial cluster
id: FBbt:00001770
in subset: cur

Axiom
annotated source: ommatidial precursor cluster
annotated property: definition
annotated target: A cluster of cells in the eye-disc that is the precursor to an adult ommatidium. Eventually there are approximately 750 ommatidial precursor clusters per eye-disc, the first forming at approximately 70hrs before pupation along the morphogenic furrow. A new row of adult ommatidial precursors then emerges from the morphogenic furrow roughly every 1.5 hours.
database_cross_reference: FlyBase:FBrf0064798

larval digestive system
type: Class
equivalent class: Class
  intersection of: digestive system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: digestive system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Any digestive system of the larva.
has alternative id: FBbt:00005764
database_cross_reference: UBERON:6001842
has exact synonym: embryonic/larval digestive system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001842
in subset: cur

Axiom
annotated source: larval digestive system
annotated property: definition
annotated target: Any digestive system of the larva.
database_cross_reference: FlyBase:FBrf0007733
database_cross_reference: FlyBase:FBrf0064792

larval nervous system
type: Class
equivalent class: Class
  intersection of: nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: nervous system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Nervous system of the embryo/larva.
has alternative id: FBbt:00005719
database_cross_reference: UBERON:6001911
database_cross_reference: VFB:FBbt_00001911
has exact synonym: embryonic/larval nervous system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001911
in subset: cur

Axiom
annotated source: larval nervous system
annotated property: definition
annotated target: Nervous system of the embryo/larva.
database_cross_reference: FlyBase:FBrf0045359
database_cross_reference: FlyBase:FBrf0075072
database_cross_reference: FlyBase:FBrf0105282

larval neuromere
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: neuromere
subclass of: Class
  intersection of: Restriction
    on property: part of
    some values from: larval segment
  intersection of: Restriction
    on property: part of
    some values from: larval central nervous system
definition: Neuromere of the larval nervous system.
database_cross_reference: VFB:FBbt_00001912
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001912
in subset: cur

Axiom
annotated source: larval neuromere
annotated property: definition
annotated target: Neuromere of the larval nervous system.
database_cross_reference: FlyBase:FBrf0047815
database_cross_reference: FlyBase:FBrf0084032
database_cross_reference: FlyBase:FBrf0089217
database_cross_reference: FlyBase:FBrf0105282

larval central nervous system
type: Class
equivalent class: Class
  intersection of: central nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: central nervous system
subclass of: Restriction
  on property: part of
  some values from: larval nervous system
definition: Central nervous system of the embryo/larva.
database_cross_reference: UBERON:6001919
database_cross_reference: VFB:FBbt_00001919
has exact synonym: embryonic/larval CNS
has exact synonym: embryonic/larval central nervous system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001919
in subset: cur
in subset: larval OF

Axiom
annotated source: larval central nervous system
annotated property: definition
annotated target: Central nervous system of the embryo/larva.
database_cross_reference: FBC:SPR

larval brain
type: Class
equivalent class: Class
  intersection of: brain
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: supraesophageal ganglion
subclass of: brain
subclass of: anterior ectoderm derivative
subclass of: Class
  intersection of: Restriction
    on property: part of
    some values from: larval head
  intersection of: Restriction
    on property: part of
    some values from: larval central nervous system
subclass of: Restriction
  on property: develops from
  some values from: embryonic brain
definition: Supraesophageal ganglion of the late embryo or larva, consisting of the protocerebrum, deutocerebrum and tritocerebrum (Urbach and Technau, 2003; Li et al., 2014; Crews, 2019).
database_cross_reference: UBERON:6001920
database_cross_reference: VFB:FBbt_00001920
has exact synonym: embryonic/larval SPG
has exact synonym: embryonic/larval brain
has exact synonym: embryonic/larval supraesophageal complex
has exact synonym: embryonic/larval supraesophageal ganglion
has exact synonym: larval SPG
has exact synonym: larval cerebral ganglion
has exact synonym: larval supraesophageal ganglion
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001920
in subset: BrainName
in subset: cur
in subset: larval OF

Axiom
annotated source: larval brain
annotated property: definition
annotated target: Supraesophageal ganglion of the late embryo or larva, consisting of the protocerebrum, deutocerebrum and tritocerebrum (Urbach and Technau, 2003; Li et al., 2014; Crews, 2019).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0225812
database_cross_reference: FlyBase:FBrf0244240

Axiom
annotated source: larval brain
annotated property: hasExactSynonym
annotated target: embryonic/larval supraesophageal complex
database_cross_reference: FlyBase:FBrf0225812

larval protocerebrum
type: Class
equivalent class: Class
  intersection of: protocerebrum
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuromere
subclass of: protocerebrum
subclass of: Restriction
  on property: part of
  some values from: larval supraesophageal zone
subclass of: Restriction
  on property: overlaps
  some values from: larval ocular segment
subclass of: Restriction
  on property: overlaps
  some values from: larval labral segment
definition: Protocerebrum of the embryo/larva.
database_cross_reference: UBERON:6001925
database_cross_reference: VFB:FBbt_00001925
database_cross_reference: larvalbrain_neuropil:392
database_cross_reference: larvalbrain_neuropil:570
has exact synonym: embryonic/larval protocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001925
in subset: cur
in subset: larval OF

Axiom
annotated source: larval protocerebrum
annotated property: definition
annotated target: Protocerebrum of the embryo/larva.
database_cross_reference: FBC:SPR

embryonic/larval optic lobe
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: larval protocerebrum
definition: Region of the embryonic or larval brain that contains the neuroepithelial cells that will give rise to the adult optic lobe, and the larval optic neuropil that processes visual information in the larva.
database_cross_reference: VFB:FBbt_00001930
database_cross_reference: larvalbrain_neuropil:391
database_cross_reference: larvalbrain_neuropil:569
has exact synonym: larval optic lobe
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001930
in subset: cur

Axiom
annotated source: embryonic/larval optic lobe
annotated property: definition
annotated target: Region of the embryonic or larval brain that contains the neuroepithelial cells that will give rise to the adult optic lobe, and the larval optic neuropil that processes visual information in the larva.
database_cross_reference: FlyBase:FBrf0052913
database_cross_reference: FlyBase:FBrf0064800
database_cross_reference: FlyBase:FBrf0215208

larval outer optic anlage
type: Class
subclass of: larval optic anlage
subclass of: Restriction
  on property: develops from
  some values from: embryonic outer optic lobe primordium
subclass of: Restriction
  on property: develops into
  some values from: lamina anlage
definition: The lateral, outer layer of the larval optic lobe. It consists of neuroepithelial cells (and later of proliferating neuroblasts) that will give rise to the neurons of the adult lamina and outer medulla. By the late first instar, it is dome shaped and perforated at its center by a pore, through which axons of the optic stalk pass (Meinertzhagen and Hanson, 1993). Some of these axons form synapses in the larval optic neuropil, which is largely within this pore (Sprecher et al., 2011). It becomes distinguished from the inner optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons. This anlage is patterned by expression of Optix and Vsx1 in complementary regions (Gold and Brand, 2014).
database_cross_reference: VFB:FBbt_00001933
has exact synonym: OOA
has exact synonym: embryonic/larval outer optic anlage
has narrow synonym: OPC
has narrow synonym: outer proliferation center
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001933
in subset: cur
comment: 'proliferation center' synonyms usually used for later stages of development (Ngo et al., 2017 - FBrf0236058).

Axiom
annotated source: larval outer optic anlage
annotated property: definition
annotated target: The lateral, outer layer of the larval optic lobe. It consists of neuroepithelial cells (and later of proliferating neuroblasts) that will give rise to the neurons of the adult lamina and outer medulla. By the late first instar, it is dome shaped and perforated at its center by a pore, through which axons of the optic stalk pass (Meinertzhagen and Hanson, 1993). Some of these axons form synapses in the larval optic neuropil, which is largely within this pore (Sprecher et al., 2011). It becomes distinguished from the inner optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons. This anlage is patterned by expression of Optix and Vsx1 in complementary regions (Gold and Brand, 2014).
database_cross_reference: FlyBase:FBrf0052913
database_cross_reference: FlyBase:FBrf0064800
database_cross_reference: FlyBase:FBrf0193624
database_cross_reference: FlyBase:FBrf0225842

Axiom
annotated source: larval outer optic anlage
annotated property: hasExactSynonym
annotated target: OOA
database_cross_reference: FlyBase:FBrf0204205

Axiom
annotated source: larval outer optic anlage
annotated property: hasNarrowSynonym
annotated target: OPC
database_cross_reference: FlyBase:FBrf0095642

Axiom
annotated source: larval outer optic anlage
annotated property: hasNarrowSynonym
annotated target: outer proliferation center
database_cross_reference: FlyBase:FBrf0095642

medulla anlage
type: Class
subclass of: anlage
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: larval optic anlage
subclass of: Restriction
  on property: develops into
  some values from: medulla
definition: A(n) anlage that develops into some medulla. It develops from some larval optic anlage.
database_cross_reference: VFB:FBbt_00001935
database_cross_reference: larvalbrain_neuropil:338
database_cross_reference: larvalbrain_neuropil:402
database_cross_reference: larvalbrain_neuropil:516
database_cross_reference: larvalbrain_neuropil:580
has exact synonym: larval medulla
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001935
in subset: cur

Axiom
annotated source: medulla anlage
annotated property: definition
annotated target: A(n) anlage that develops into some medulla. It develops from some larval optic anlage.
database_cross_reference: FBC:Autogenerated

medulla forming neuroblast
type: Class
subclass of: optic neuroblast
subclass of: Restriction
  on property: part of
  some values from: larval optic anlage
subclass of: Restriction
  on property: expresses
  some values from: FBgn0000137
subclass of: Restriction
  on property: expresses
  some values from: FBgn0010109
definition: A neuroblast that is the precursor of the medulla. The neuroblasts that give rise to the outer medulla neurons are located in the medial edge of the larval outer optic anlage, whereas the neuroblasts that give rise to the inner medulla neurons are located in the larval inner optic anlage.
database_cross_reference: VFB:FBbt_00001938
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001938
in subset: cur
comment: Can be distinguished from other optic lobe neuroblasts based on expression of dpn and ase (Konstantinides et al., 2022).

Axiom
annotated source: medulla forming neuroblast
annotated property: definition
annotated target: A neuroblast that is the precursor of the medulla. The neuroblasts that give rise to the outer medulla neurons are located in the medial edge of the larval outer optic anlage, whereas the neuroblasts that give rise to the inner medulla neurons are located in the larval inner optic anlage.
database_cross_reference: FlyBase:FBrf0193624
database_cross_reference: FlyBase:FBrf0214710
database_cross_reference: FlyBase:FBrf0253187

lamina anlage
type: Class
subclass of: anlage
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: larval outer optic anlage
subclass of: Restriction
  on property: develops into
  some values from: lamina
definition: A zone of proliferating neuroblasts that forms at mid third instar, at the lateral rim of the outer optic anlage. Descendants of these neuroblasts form the adult lamina.
has alternative id: FBbt:00001950
database_cross_reference: VFB:FBbt_00001939
database_cross_reference: larvalbrain_neuropil:376
database_cross_reference: larvalbrain_neuropil:554
has exact synonym: larval lamina
has exact synonym: lateral proliferation zone
has exact synonym: lpo
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001939
in subset: cur

Axiom
annotated source: lamina anlage
annotated property: definition
annotated target: A zone of proliferating neuroblasts that forms at mid third instar, at the lateral rim of the outer optic anlage. Descendants of these neuroblasts form the adult lamina.
database_cross_reference: FlyBase:FBrf0052913

Axiom
annotated source: lamina anlage
annotated property: hasExactSynonym
annotated target: lpo
database_cross_reference: FlyBase:FBrf0052913

lobula anlage
type: Class
subclass of: anlage
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: larval inner optic anlage
subclass of: Restriction
  on property: develops into
  some values from: lobula
definition: Anlage of the embryo/larva that is the precursor to the adult lobula.
database_cross_reference: VFB:FBbt_00001944
database_cross_reference: larvalbrain_neuropil:378
database_cross_reference: larvalbrain_neuropil:400
database_cross_reference: larvalbrain_neuropil:556
database_cross_reference: larvalbrain_neuropil:578
has exact synonym: larval lobula
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001944
in subset: cur

Axiom
annotated source: lobula anlage
annotated property: definition
annotated target: Anlage of the embryo/larva that is the precursor to the adult lobula.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

lobula plate anlage
type: Class
subclass of: anlage
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: larval inner optic anlage
subclass of: Restriction
  on property: develops into
  some values from: lobula plate
definition: A(n) anlage that develops into some lobula plate. It develops from some larval inner optic anlage.
database_cross_reference: VFB:FBbt_00001946
database_cross_reference: larvalbrain_neuropil:380
database_cross_reference: larvalbrain_neuropil:401
database_cross_reference: larvalbrain_neuropil:558
database_cross_reference: larvalbrain_neuropil:579
has exact synonym: larval lobula plate
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001946
in subset: cur

Axiom
annotated source: lobula plate anlage
annotated property: definition
annotated target: A(n) anlage that develops into some lobula plate. It develops from some larval inner optic anlage.
database_cross_reference: FBC:Autogenerated

cell body rind of adult lobula plate
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult optic lobe
subclass of: Restriction
  on property: continuous with
  some values from: lobula plate
definition: Region of the adult brain cell body rind that overlies the lobula plate.
database_cross_reference: VFB:FBbt_00001948
has exact synonym: cortex of lobula plate
has exact synonym: lobula plate cortex
has exact synonym: rLOP
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001948
in subset: cur

Axiom
annotated source: cell body rind of adult lobula plate
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the lobula plate.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult lobula plate
annotated property: hasExactSynonym
annotated target: rLOP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

larval inner optic anlage
type: Class
subclass of: larval optic anlage
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: lobula anlage
  intersection of: Restriction
    on property: develops into
    some values from: lobula plate anlage
subclass of: Restriction
  on property: develops from
  some values from: embryonic inner optic lobe primordium
definition: A ribbon-like layer of neuroepithelial cells (and later of proliferating neuroblasts) in the larval optic lobe that gives rise to the adult inner medulla, lobula and lobula plate neurons. In early larval stages it is composed of neuroepithelial cells that divide symmetrically. In the early second instar it becomes U shaped, with the opening of the U pointing in a dorso-caudal direction. It becomes distinguished from the outer optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons.
database_cross_reference: VFB:FBbt_00001951
has exact synonym: IOA
has exact synonym: embryonic/larval inner optic anlage
has narrow synonym: IPC
has narrow synonym: inner proliferation center
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001951
in subset: cur
comment: 'proliferation center' synonyms usually used for later stages of development (Ngo et al., 2017 - FBrf0236058).

Axiom
annotated source: larval inner optic anlage
annotated property: definition
annotated target: A ribbon-like layer of neuroepithelial cells (and later of proliferating neuroblasts) in the larval optic lobe that gives rise to the adult inner medulla, lobula and lobula plate neurons. In early larval stages it is composed of neuroepithelial cells that divide symmetrically. In the early second instar it becomes U shaped, with the opening of the U pointing in a dorso-caudal direction. It becomes distinguished from the outer optic anlage during the second half of the first instar period (Meinertzhagen and Hanson, 1993). In the third instar, neuroepithelial cells in the medial region give rise to neuroblasts that divide asymmetrically to generate the adult optic lobe neurons.
database_cross_reference: FlyBase:FBrf0052913
database_cross_reference: FlyBase:FBrf0193624

Axiom
annotated source: larval inner optic anlage
annotated property: hasExactSynonym
annotated target: IOA
database_cross_reference: FlyBase:FBrf0204205

Axiom
annotated source: larval inner optic anlage
annotated property: hasNarrowSynonym
annotated target: IPC
database_cross_reference: FlyBase:FBrf0095642

Axiom
annotated source: larval inner optic anlage
annotated property: hasNarrowSynonym
annotated target: inner proliferation center
database_cross_reference: FlyBase:FBrf0095642

larval deutocerebrum
type: Class
equivalent class: Class
  intersection of: larval neuromere
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: larval neuromere
subclass of: deutocerebrum
subclass of: Restriction
  on property: part of
  some values from: larval antennal segment
subclass of: Restriction
  on property: part of
  some values from: larval central brain
subclass of: Restriction
  on property: part of
  some values from: larval supraesophageal zone
definition: Deutocerebrum of the embryo/larva.
database_cross_reference: VFB:FBbt_00001957
database_cross_reference: larvalbrain_neuropil:337
database_cross_reference: larvalbrain_neuropil:515
has exact synonym: embryonic/larval deuterocerebrum
has exact synonym: embryonic/larval deutocerebrum
has exact synonym: larval deuterocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001957
in subset: cur
in subset: larval OF

Axiom
annotated source: larval deutocerebrum
annotated property: definition
annotated target: Deutocerebrum of the embryo/larva.
database_cross_reference: FBC:SPR

larval tritocerebrum
type: Class
equivalent class: Class
  intersection of: larval neuromere
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: larval neuromere
subclass of: tritocerebrum
subclass of: Restriction
  on property: part of
  some values from: larval intercalary segment
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval periesophageal neuropils
subclass of: Restriction
  on property: part of
  some values from: larval central brain
subclass of: Restriction
  on property: overlaps
  some values from: larval subesophageal zone
subclass of: Restriction
  on property: overlaps
  some values from: larval supraesophageal zone
definition: Tritocerebrum of the late embryonic or larval brain. It is found at the base of the brain hemispheres, partially below the esophagus (Hartenstein et al., 2015; Hartenstein et al., 2018).
database_cross_reference: VFB:FBbt_00001962
database_cross_reference: larvalbrain_neuropil:418
database_cross_reference: larvalbrain_neuropil:596
has exact synonym: embryonic/larval tritocerebrum
has exact synonym: larval PENPa
has exact synonym: larval anterior periesophageal neuropils
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001962
in subset: cur

Axiom
annotated source: larval tritocerebrum
annotated property: definition
annotated target: Tritocerebrum of the late embryonic or larval brain. It is found at the base of the brain hemispheres, partially below the esophagus (Hartenstein et al., 2015; Hartenstein et al., 2018).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0229672
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: larval tritocerebrum
annotated property: hasExactSynonym
annotated target: larval PENPa
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: larval tritocerebrum
annotated property: hasExactSynonym
annotated target: larval anterior periesophageal neuropils
database_cross_reference: FlyBase:FBrf0229672

supraesophageal nerve
type: Class
equivalent class: Class
  intersection of: nerve
  intersection of: Restriction
    on property: innervates
    some values from: supraesophageal ganglion
subclass of: nerve
subclass of: Restriction
  on property: innervates
  some values from: supraesophageal ganglion
definition: Nerve that innervates the supraesophageal ganglion.
database_cross_reference: VFB:FBbt_00001964
has OBO namespace: fly_anatomy.ontology
id: FBbt:00001964
in subset: cur
in subset: larval OF

Axiom
annotated source: supraesophageal nerve
annotated property: definition
annotated target: Nerve that innervates the supraesophageal ganglion.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

subesophageal zone neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: subesophageal zone
subclass of: CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: subesophageal zone
definition: Any neuron (FBbt:00005106) that has its soma located in some subesophageal zone (FBbt:00051068).
database_cross_reference: VFB:FBbt_00001972
has exact synonym: SEZ neuron
has OBO namespace: fly_anatomy.ontology
has related synonym: SEG neuron
has related synonym: SOG neuron
has related synonym: subesophageal ganglion neuron
id: FBbt:00001972
in subset: cur

Axiom
annotated source: subesophageal zone neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has its soma located in some subesophageal zone (FBbt:00051068).
database_cross_reference: FBC:Autogenerated

larval sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Any sense organ of the larva.
database_cross_reference: UBERON:6002639
database_cross_reference: VFB:FBbt_00002639
has exact synonym: embryonic/larval sense organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002639
in subset: cur

Axiom
annotated source: larval sense organ
annotated property: definition
annotated target: Any sense organ of the larva.
database_cross_reference: FBC:Autogenerated

larval ocular segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: ocular segment
subclass of: embryonic/larval head sense organ
subclass of: Restriction
  on property: part of
  some values from: larval ocular segment
definition: Any larval sense organ (FBbt:00002639) that is part of some ocular segment (FBbt:00000005).
database_cross_reference: UBERON:6002642
database_cross_reference: VFB:FBbt_00002642
has narrow synonym: embryonic/larval ocular segment sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002642
in subset: cur

Axiom
annotated source: larval ocular segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some ocular segment (FBbt:00000005).
database_cross_reference: FBC:Autogenerated

embryonic/larval labral segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: labral segment
subclass of: embryonic/larval head sense organ
subclass of: Restriction
  on property: part of
  some values from: larval labral segment
definition: Any larval sense organ (FBbt:00002639) that is part of some labral segment (FBbt:00000008).
has alternative id: FBbt:00002650
database_cross_reference: VFB:FBbt_00002649
has exact synonym: larval labral segment sense organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002649
in subset: cur

Axiom
annotated source: embryonic/larval labral segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some labral segment (FBbt:00000008).
database_cross_reference: FBC:Autogenerated

larval antennal segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: antennal sense organ
subclass of: embryonic/larval head sense organ
subclass of: Restriction
  on property: part of
  some values from: larval antennal segment
definition: Any larval sense organ (FBbt:00002639) that is part of some antennal segment (FBbt:00000009).
database_cross_reference: VFB:FBbt_00002654
has narrow synonym: embryonic/larval antennal segment sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002654
in subset: cur

Axiom
annotated source: larval antennal segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some antennal segment (FBbt:00000009).
database_cross_reference: FBC:Autogenerated

intercalary segment sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: intercalary segment
definition: Any sense organ (FBbt:00005155) that is part of some intercalary segment (FBbt:00000010).
database_cross_reference: VFB:FBbt_00002664
has OBO namespace: fly_anatomy.ontology
id: FBbt:00002664
in subset: cur

Axiom
annotated source: intercalary segment sense organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is part of some intercalary segment (FBbt:00000010).
database_cross_reference: FBC:Autogenerated

prepupa
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: larva
definition: The prepupa is the name given to the organism at the period of the life cycle that begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C is approximately 12 hours. It occurs 120-132.2 hours after egg laying, and is the period of 0-12.2 hours after puparium formation.
database_cross_reference: UBERON:0003142
has OBO namespace: fly_anatomy.ontology
has related synonym: PP
id: FBbt:00002952
in subset: FB gloss
in subset: cur

Axiom
annotated source: prepupa
annotated property: definition
annotated target: The prepupa is the name given to the organism at the period of the life cycle that begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C is approximately 12 hours. It occurs 120-132.2 hours after egg laying, and is the period of 0-12.2 hours after puparium formation.
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

pupa
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: prepupa
definition: The pupa is the name given to the organism at the period of the life cycle that begins once larval/pupal apolysis is complete, as indicated by the expulsion of the larval armature. Early in this stage the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. The duration of this stage is approximately 32 hours at 25 degrees C, and spans from 132.2-164.3 hours after egg laying, or is the period of 12.2-44.3 hours after puparium formation.
database_cross_reference: UBERON:0003143
has OBO namespace: fly_anatomy.ontology
has related synonym: P
id: FBbt:00002953
in subset: FB gloss
in subset: cur

Axiom
annotated source: pupa
annotated property: definition
annotated target: The pupa is the name given to the organism at the period of the life cycle that begins once larval/pupal apolysis is complete, as indicated by the expulsion of the larval armature. Early in this stage the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. The duration of this stage is approximately 32 hours at 25 degrees C, and spans from 132.2-164.3 hours after egg laying, or is the period of 12.2-44.3 hours after puparium formation.
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

adult
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: pharate adult
definition: Organism at any stage after completing eclosion.
database_cross_reference: UBERON:0007023
has OBO namespace: fly_anatomy.ontology
has related synonym: imago
id: FBbt:00003004
in subset: FB gloss
in subset: cur

Axiom
annotated source: adult
annotated property: definition
annotated target: Organism at any stage after completing eclosion.
database_cross_reference: FlyBase:FBrf0036849

adult tagma
type: Class
equivalent class: Class
  intersection of: tagma
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: tagma
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Any tagma of the adult.
database_cross_reference: UBERON:6003005
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003005
in subset: cur

Axiom
annotated source: adult tagma
annotated property: definition
annotated target: Any tagma of the adult.
database_cross_reference: FBC:Autogenerated

adult segment
type: Class
equivalent class: Class
  intersection of: segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: segment
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Segment of the adult.
database_cross_reference: UBERON:6003006
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003006
in subset: cur

Axiom
annotated source: adult segment
annotated property: definition
annotated target: Segment of the adult.
database_cross_reference: FBC:SPR

adult head
type: Class
equivalent class: Class
  intersection of: head
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: head
subclass of: adult tagma
definition: Head of the adult organism.
database_cross_reference: UBERON:6003007
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003007
in subset: cur

Axiom
annotated source: adult head
annotated property: definition
annotated target: Head of the adult organism.
database_cross_reference: FBC:SPR

adult ocular segment
type: Class
equivalent class: Class
  intersection of: ocular segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: ocular segment
subclass of: adult procephalic segment
definition: Any ocular segment of the adult.
has OBO namespace: fly_anatomy.ontology
has related synonym: adult acron
id: FBbt:00003008
in subset: cur

Axiom
annotated source: adult ocular segment
annotated property: definition
annotated target: Any ocular segment of the adult.
database_cross_reference: FBC:Autogenerated

adult head segment
type: Class
equivalent class: Class
  intersection of: head segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: head segment
subclass of: adult segment
subclass of: Restriction
  on property: part of
  some values from: adult head
definition: Segment of the adult head.
database_cross_reference: UBERON:6003009
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003009
in subset: cur

Axiom
annotated source: adult head segment
annotated property: definition
annotated target: Segment of the adult head.
database_cross_reference: FlyBase:FBrf0064788

adult procephalic segment
type: Class
equivalent class: Class
  intersection of: procephalic segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: procephalic segment
subclass of: adult head segment
definition: Any procephalic segment of the adult.
database_cross_reference: UBERON:6003010
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003010
in subset: cur

Axiom
annotated source: adult procephalic segment
annotated property: definition
annotated target: Any procephalic segment of the adult.
database_cross_reference: FBC:Autogenerated

adult labral segment
type: Class
equivalent class: Class
  intersection of: labral segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: labral segment
subclass of: adult procephalic segment
definition: Any labral segment of the adult.
database_cross_reference: UBERON:6003011
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003011
in subset: cur

Axiom
annotated source: adult labral segment
annotated property: definition
annotated target: Any labral segment of the adult.
database_cross_reference: FBC:Autogenerated

adult antennal segment
type: Class
equivalent class: Class
  intersection of: antennal segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: antennal segment
subclass of: adult procephalic segment
definition: Any antennal segment of the adult.
has alternative id: FBbt:00004512
database_cross_reference: UBERON:6003012
has exact synonym: adult antennal structure
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003012
in subset: cur

Axiom
annotated source: adult antennal segment
annotated property: definition
annotated target: Any antennal segment of the adult.
database_cross_reference: FBC:Autogenerated

adult intercalary segment
type: Class
equivalent class: Class
  intersection of: intercalary segment
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: intercalary segment
subclass of: adult procephalic segment
definition: Any intercalary segment of the adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003013
in subset: cur

Axiom
annotated source: adult intercalary segment
annotated property: definition
annotated target: Any intercalary segment of the adult.
database_cross_reference: FBC:Autogenerated

adult digestive system
type: Class
equivalent class: Class
  intersection of: digestive system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: digestive system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Digestive system of the adult, comprising the alimentary canal, mouthparts, labellar glands, salivary glands and Malpighian tubules (Miller, 1950). The adult alimentary canal and salivary glands arise anew from precursors during metamorphosis (Bodenstein, 1950). The adult Malpighian tubules are remodelled from those of the larva (Bodenstein, 1950).
has OBO namespace: fly_anatomy.ontology
has related synonym: pupal/adult digestive system
id: FBbt:00003123
in subset: cur

Axiom
annotated source: adult digestive system
annotated property: definition
annotated target: Digestive system of the adult, comprising the alimentary canal, mouthparts, labellar glands, salivary glands and Malpighian tubules (Miller, 1950). The adult alimentary canal and salivary glands arise anew from precursors during metamorphosis (Bodenstein, 1950). The adult Malpighian tubules are remodelled from those of the larva (Bodenstein, 1950).
database_cross_reference: FlyBase:FBrf0007733
database_cross_reference: FlyBase:FBrf0007735

alimentary canal
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: digestive system
definition: The entire anatomical structure through which food and its digestion products are ingested, digested and excreted. At its anterior and posterior ends this includes structures that are not foregut or hindgut.
database_cross_reference: UBERON:0001555
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003125
in subset: cur

Axiom
annotated source: alimentary canal
annotated property: definition
annotated target: The entire anatomical structure through which food and its digestion products are ingested, digested and excreted. At its anterior and posterior ends this includes structures that are not foregut or hindgut.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult apodeme
type: Class
equivalent class: Class
  intersection of: apodeme
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: apodeme
subclass of: Restriction
  on property: part of
  some values from: adult integumentary system
definition: Apodeme that is part of an adult.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003516
in subset: cur
in subset: hidden assertion

Axiom
annotated source: adult apodeme
annotated property: definition
annotated target: Apodeme that is part of an adult.
database_cross_reference: FBC:SPR

adult nervous system
type: Class
equivalent class: Class
  intersection of: nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: nervous system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Any nervous system of the adult.
database_cross_reference: UBERON:6003559
database_cross_reference: VFB:FBbt_00003559
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003559
in subset: cur

Axiom
annotated source: adult nervous system
annotated property: definition
annotated target: Any nervous system of the adult.
database_cross_reference: FlyBase:FBrf0002482
database_cross_reference: FlyBase:FBrf0007196
database_cross_reference: FlyBase:FBrf0007735
database_cross_reference: FlyBase:FBrf0034076

adult central nervous system
type: Class
equivalent class: Class
  intersection of: central nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: central nervous system
subclass of: Restriction
  on property: part of
  some values from: adult nervous system
definition: Central nervous system of the adult.
database_cross_reference: UBERON:6003623
database_cross_reference: VFB:FBbt_00003623
has exact synonym: adult CNS
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003623
in subset: cur

Axiom
annotated source: adult central nervous system
annotated property: definition
annotated target: Central nervous system of the adult.
database_cross_reference: FBC:SPR

adult brain
type: Class
equivalent class: Class
  intersection of: brain
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: brain
subclass of: Class
  intersection of: Restriction
    on property: part of
    some values from: adult head
  intersection of: Restriction
    on property: part of
    some values from: adult central nervous system
definition: Portion of the adult central nervous system found in the head, consisting of the cerebral and gnathal ganglia (Ito et al., 2014).
database_cross_reference: UBERON:6003624
database_cross_reference: VFB:FBbt_00003624
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003624
in subset: BrainName
in subset: cur

Axiom
annotated source: adult brain
annotated property: definition
annotated target: Portion of the adult central nervous system found in the head, consisting of the cerebral and gnathal ganglia (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

adult brain cell body rind
type: Class
subclass of: cell body rind of adult central nervous system
subclass of: Restriction
  on property: part of
  some values from: adult brain
definition: Superficial layer of the brain, composed of glia and the cell bodies of neurons (soma).
database_cross_reference: VFB:FBbt_00003625
has exact synonym: adult brain cortex
has OBO namespace: fly_anatomy.ontology
has related synonym: cerebral cortex
id: FBbt:00003625
in subset: cur
comment: Ito et al. (2014) may further subdivide cortex/rind regions into multiple facets. Subdivisions should be denoted by the addition of a single letter body-axis direction, e.g. rLHa for anterior to the lateral horn; rSMPm for medial to the superior medial protocerebrum, etc.

Axiom
annotated source: adult brain cell body rind
annotated property: definition
annotated target: Superficial layer of the brain, composed of glia and the cell bodies of neurons (soma).
database_cross_reference: FBC:VH

supraesophageal ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: part of
  some values from: brain
definition: The pre-oral neuropils of the brain located above and some of it below the esophagus, comprising three fused ganglia (protocerebrum, deutocerebrum, and tritocerebrum) in the head.
database_cross_reference: UBERON:6003626
database_cross_reference: VFB:FBbt_00003626
has OBO namespace: fly_anatomy.ontology
has related synonym: SPG
id: FBbt:00003626
in subset: BrainName
in subset: cur
comment: In the adult, this region is referred to as cerebral ganglia (Ito et al., 2014).

Axiom
annotated source: supraesophageal ganglion
annotated property: definition
annotated target: The pre-oral neuropils of the brain located above and some of it below the esophagus, comprising three fused ganglia (protocerebrum, deutocerebrum, and tritocerebrum) in the head.
database_cross_reference: FlyBase:FBrf0224194

protocerebrum
type: Class
subclass of: neuromere
subclass of: Restriction
  on property: part of
  some values from: supraesophageal zone
subclass of: Restriction
  on property: overlaps
  some values from: ocular segment
subclass of: Restriction
  on property: overlaps
  some values from: labral segment
definition: The most anterior neuromere of the central nervous system, developing from neuroblasts of the labral and ocular segments (Urbach and Technau, 2003; Ito et al., 2014). The protocerebrum comprises many discrete neuropil regions including the central complex and mushroom bodies (Ito et al., 2014).
database_cross_reference: UBERON:6003627
database_cross_reference: VFB:FBbt_00003627
has exact synonym: PR
has exact synonym: protocerebral neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003627
in subset: cur
comment: Urbach and Technau (2003) divide the protocerebrum into labral and ocular neuromeres.

Axiom
annotated source: protocerebrum
annotated property: definition
annotated target: The most anterior neuromere of the central nervous system, developing from neuroblasts of the labral and ocular segments (Urbach and Technau, 2003; Ito et al., 2014). The protocerebrum comprises many discrete neuropil regions including the central complex and mushroom bodies (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: protocerebrum
annotated property: hasExactSynonym
annotated target: PR
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: protocerebrum
annotated property: hasExactSynonym
annotated target: protocerebral neuromere
database_cross_reference: FlyBase:FBrf0092819

optic glomerulus
type: Class
subclass of: glomerulus
subclass of: Restriction
  on property: part of
  some values from: ventrolateral neuropils
subclass of: Restriction
  on property: part of
  some values from: visual system
definition: Small and discrete area of the ventrolateral neuropils defined by the presynaptic terminals of visual projection neurons carrying sensory information from the optic lobe (Otsuna and Ito, 2006; Wu et al., 2016).
has alternative id: FBbt:00040032
database_cross_reference: VFB:FBbt_00003698
has exact synonym: optic focus
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003698
in subset: cur

Axiom
annotated source: optic glomerulus
annotated property: definition
annotated target: Small and discrete area of the ventrolateral neuropils defined by the presynaptic terminals of visual projection neurons carrying sensory information from the optic lobe (Otsuna and Ito, 2006; Wu et al., 2016).
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: optic glomerulus
annotated property: hasExactSynonym
annotated target: optic focus
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0239031

adult optic lobe
type: Class
subclass of: multi-tissue structure
subclass of: adult primary visual center
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: part of
  some values from: visual system
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval optic lobe
definition: A region of the adult brain that processes visual information from the compound eyes.
database_cross_reference: UBERON:0006795
database_cross_reference: VFB:FBbt_00003701
has exact synonym: OL
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003701
in subset: BrainName
in subset: FB gloss
in subset: cur

Axiom
annotated source: adult optic lobe
annotated property: definition
annotated target: A region of the adult brain that processes visual information from the compound eyes.
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0166419

Axiom
annotated source: adult optic lobe
annotated property: hasExactSynonym
annotated target: OL
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

adult optic lobe neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: adult optic lobe
subclass of: supraesophageal ganglion neuron
subclass of: anterior ectoderm derivative
subclass of: adult CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult optic lobe
subclass of: Restriction
  on property: develops from
  some values from: immature adult optic lobe neuron
definition: Neuron that has its cell body in the adult optic lobe. These neurons develop from neuroblasts of the larval optic anlage (Hofbauer and Campos-Ortega, 1990).
database_cross_reference: VFB:FBbt_00003702
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003702
in subset: cur

Axiom
annotated source: adult optic lobe neuron
annotated property: definition
annotated target: Neuron that has its cell body in the adult optic lobe. These neurons develop from neuroblasts of the larval optic anlage (Hofbauer and Campos-Ortega, 1990).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0052913
database_cross_reference: FlyBase:FBrf0064800
database_cross_reference: FlyBase:FBrf0226618

lamina
type: Class
subclass of: anterior ectoderm derivative
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
subclass of: Restriction
  on property: develops from
  some values from: lamina anlage
definition: Lateral-most synaptic neuropil domain of the adult optic lobes, lying just beneath the compound eyes. It is composed of an array of repetitive cartridge-like units, each of which receives axons from specific sets of ommatidia in the compound eyes.
database_cross_reference: VFB:FBbt_00003708
has exact synonym: LA
has OBO namespace: fly_anatomy.ontology
has related synonym: La
id: FBbt:00003708
in subset: BrainName
in subset: cur

Axiom
annotated source: lamina
annotated property: definition
annotated target: Lateral-most synaptic neuropil domain of the adult optic lobes, lying just beneath the compound eyes. It is composed of an array of repetitive cartridge-like units, each of which receives axons from specific sets of ommatidia in the compound eyes.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0231227
database_cross_reference: VFB_vol:00003708

Axiom
annotated source: lamina
annotated property: hasExactSynonym
annotated target: LA
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

lamina monopolar neuron
type: Class
subclass of: optic lobe intrinsic columnar neuron
subclass of: optic lobe narrow field columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult lamina
subclass of: Restriction
  on property: overlaps
  some values from: optic cartridge
subclass of: Restriction
  on property: overlaps
  some values from: first optic chiasma
subclass of: Restriction
  on property: develops from
  some values from: immature lamina monopolar neuron
definition: Monopolar, intrinsic unicolumnar neuron of the adult optic lobe that has its soma in the cell body rind of the lamina and connects the lamina to the medulla (Fischbach and Dittrich, 1989). It has a single major projection that projects along one optic cartridge in the lamina, crosses the first optic chiasm and terminates in the same cartridge in the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: VFB:FBbt_00003718
has exact synonym: LMC
has exact synonym: lamina monopolar cell
has exact synonym: monopolar laminar cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003718
in subset: cur

Axiom
annotated source: lamina monopolar neuron
annotated property: definition
annotated target: Monopolar, intrinsic unicolumnar neuron of the adult optic lobe that has its soma in the cell body rind of the lamina and connects the lamina to the medulla (Fischbach and Dittrich, 1989). It has a single major projection that projects along one optic cartridge in the lamina, crosses the first optic chiasm and terminates in the same cartridge in the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410

lamina monopolar neuron L1
type: Class
subclass of: lamina monopolar neuron
subclass of: adult glutamatergic neuron
subclass of: Restriction
  on property: electrically_synapsed_to
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: develops from
  some values from: immature lamina monopolar neuron L1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R6
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: centrifugal neuron C3
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm3
IAO_0000028: L1
definition: Lamina monopolar neuron that has short collaterals projecting radially from the main projection in the lamina and arborization in medulla layers M1 and M5 (Fischbach and Dittrich, 1989; Kind et al., 2021). In the lamina, these short collaterals are strongly postsynaptic to the terminals of photoreceptors R1-6 (Rivera-Alba et al., 2011). In the medulla, it makes strong reciprocal synaptic connections with lamina monopolar cell L5 and centrifugal neuron C2, as well as substantial output synapses to C3, Mi1 and Tm3 cells (Takemura et al., 2013). It is also electrically synapsed to lamina monopolar neuron L2 (Joesch et al., 2010). It is a glutamatergic neuron (Gao et al., 2008; Takemura et al., 2011). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10089
database_cross_reference: VFB:FBbt_00003719
has exact synonym: L1
has exact synonym: monopolar laminar cell L1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003719
in subset: cur
comment: The neurotransmitter was assessed by labelling cells with a vGlut[OK371]-dVP16AD-GAL4 driver (FBti0129742) (Gao et al., 2008) or by single cell RT-PCR with specific primers (Takemura et al., 2011). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for L1 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (-/40), R2 (-/43), R3 (-/37), R4 (-/38), R5 (-/38), R6 (-/45), L2 (-/3), Lai (-/1), C3 (-/3) and Lawf (-/1) (Rivera-Alba et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013). Electrical connectivity was shown by dye labelling (Joesch et al., 2010).

Axiom
annotated source: lamina monopolar neuron L1
annotated property: IAO_0000028
annotated target: L1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L1
annotated property: definition
annotated target: Lamina monopolar neuron that has short collaterals projecting radially from the main projection in the lamina and arborization in medulla layers M1 and M5 (Fischbach and Dittrich, 1989; Kind et al., 2021). In the lamina, these short collaterals are strongly postsynaptic to the terminals of photoreceptors R1-6 (Rivera-Alba et al., 2011). In the medulla, it makes strong reciprocal synaptic connections with lamina monopolar cell L5 and centrifugal neuron C2, as well as substantial output synapses to C3, Mi1 and Tm3 cells (Takemura et al., 2013). It is also electrically synapsed to lamina monopolar neuron L2 (Joesch et al., 2010). It is a glutamatergic neuron (Gao et al., 2008; Takemura et al., 2011). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0212262
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina monopolar neuron L1
annotated property: hasExactSynonym
annotated target: L1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina monopolar neuron L2
type: Class
subclass of: lamina monopolar neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: electrically_synapsed_to
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: develops from
  some values from: immature lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R6
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: columnar neuron T1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm4
IAO_0000028: L2
definition: A lamina monopolar neuron with short collaterals that project radially from the main projection in the lamina and that arborizes in medulla layer M2. In the lamina it receives strong input from photoreceptors R1-R6 (Rivera-Alba et al., 2011). It has both pre- and postsynaptic connections in medulla layer M2, with strong synaptic input coming from centrifugal neurons C2 and C3 (Takemura et al., 2013). It has a large number of presynaptic connections to lamina monopolar neuron L5, columnar neuron T1, and transmedullary neurons Tm1, Tm2 and Tm4 (Takemura et al., 2013). It is a cholinergic neuron (Takemura et al., 2011) and is electrically synapsed to lamina monopolar neuron L1 (Joesch et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10090
database_cross_reference: VFB:FBbt_00003720
has exact synonym: L2
has exact synonym: monopolar laminar cell L2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003720
in subset: cur
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for L2 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (1/46), R2 (1/45), R3 (-/39), R4 (-/41), R5 (-/39), R6 (-/47), L1 (3/-), L4 (10/7), L5 (1/-), Lai (-/1), C2 (-/3), C3 (-/5) and Lwf (-/7) (Rivera-Alba et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013). Note that for many of the output synapses in M2, Tm1 and Tm2 share the same sites (Takemura et al., 2008; Takemura et al., 2011). Electrical connectivity was shown by dye labelling (Joesch et al., 2010). The neurotransmitter was assessed by single cell RT-PCR measurement of choline acetyltransferase (FBgn0000303) expression (Takemura et al., 2011).

Axiom
annotated source: lamina monopolar neuron L2
annotated property: IAO_0000028
annotated target: L2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L2
annotated property: definition
annotated target: A lamina monopolar neuron with short collaterals that project radially from the main projection in the lamina and that arborizes in medulla layer M2. In the lamina it receives strong input from photoreceptors R1-R6 (Rivera-Alba et al., 2011). It has both pre- and postsynaptic connections in medulla layer M2, with strong synaptic input coming from centrifugal neurons C2 and C3 (Takemura et al., 2013). It has a large number of presynaptic connections to lamina monopolar neuron L5, columnar neuron T1, and transmedullary neurons Tm1, Tm2 and Tm4 (Takemura et al., 2013). It is a cholinergic neuron (Takemura et al., 2011) and is electrically synapsed to lamina monopolar neuron L1 (Joesch et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0212262
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina monopolar neuron L2
annotated property: hasExactSynonym
annotated target: L2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina monopolar neuron L3
type: Class
subclass of: lamina monopolar neuron
subclass of: adult GABAergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature lamina monopolar neuron L3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: outer photoreceptor cell
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: inner photoreceptor cell
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi9
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm20
IAO_0000028: L3
definition: Lamina monopolar neuron with short spines that project to one side of the main projection as it extends through the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It terminates with an arborization in medulla layer M3 (Fischbach and Dittrich, 1989; Kind et al., 2021). In the lamina it is postsynaptic to the outer photoreceptors (R1-R6) (Rivera-Alba et al., 2011). It also receives input from the inner photoreceptors, partly in the first optic chiasm and partly in the medulla (Kind et al., 2021). It forms presynaptic terminals in medulla layer M3 (Takemura et al., 2008), with strong outputs to Mi9 and Tm20 (Takemura et al., 2013). It is a GABAergic neuron (Raghu et al., 2013). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10091
database_cross_reference: VFB:FBbt_00003721
has exact synonym: L3
has exact synonym: monopolar laminar cell L3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003721
in subset: cur
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for L3 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (-/11), R2 (-/10), R3 (-/4), R4 (-/8), R5 (-/6), R6 (-/12), L4 (-/1), L5 (1/-), Lai (-/10) and Lawf (-/17) (Rivera-Alba et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013). The neurotransmitter was assessed by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA (Raghu et al., 2013).

Axiom
annotated source: lamina monopolar neuron L3
annotated property: IAO_0000028
annotated target: L3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L3
annotated property: definition
annotated target: Lamina monopolar neuron with short spines that project to one side of the main projection as it extends through the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It terminates with an arborization in medulla layer M3 (Fischbach and Dittrich, 1989; Kind et al., 2021). In the lamina it is postsynaptic to the outer photoreceptors (R1-R6) (Rivera-Alba et al., 2011). It also receives input from the inner photoreceptors, partly in the first optic chiasm and partly in the medulla (Kind et al., 2021). It forms presynaptic terminals in medulla layer M3 (Takemura et al., 2008), with strong outputs to Mi9 and Tm20 (Takemura et al., 2013). It is a GABAergic neuron (Raghu et al., 2013). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0220286
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina monopolar neuron L3
annotated property: hasExactSynonym
annotated target: L3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina monopolar neuron L4
type: Class
subclass of: CL_0008061
subclass of: lamina monopolar neuron
subclass of: adult cholinergic neuron
subclass of: adult GABAergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature lamina monopolar neuron L4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm2
IAO_0000028: L4
definition: A lamina monopolar neuron that arborizes in the proximal lamina, forms a spreading arbor in medulla layer M2 and a small terminal arbor in M4-M5 that penetrates adjacent columns (Fischbach and Dittrich, 1989; Takemura et al., 2008; Takemura et al., 2011). In the medulla it forms presynaptic terminals in both M2 and M4-M5 with transmedullary neuron Tm2; three L4 neurons, one from the parent column and two from the posterior ones contact the same Tm2 neuron (Takemura et al., 2008; Takemura et al., 2011). It seems to be capable of both cholinergic and GABAergic neurotransmission.
has alternative id: FBbt:00003723
has alternative id: FBbt:00003724
database_cross_reference: FlyBrain_NDB:10092
database_cross_reference: VFB:FBbt_00003722
has exact synonym: L4
has exact synonym: monopolar laminar cell L4
has exact synonym: monopolar laminar cell L4x
has exact synonym: monopolar laminar cell L4y
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003722
in subset: cur
comment: Note, Fischbach and Dittrich (1989) have this as arborizing in M4, but we follow the more detailed analysis of Takemura and colleagues (2008) who place the terminal arbor in M5. This difference may have to do with the different ways the two papers define L4. Note also that L4x and L4y are simply a way of referring to L4 collaterals from an adjacent cartridge in descriptions of synaptic connectivity (see Meinertzhagen and O'Neil, 1991) and are not separate neurons. Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008; Takemura et al., 2011). Takemura et al. (2011) and Davis et al. (2020) report the neurotransmitter to be acetylcholine as assessed by single cell RT-PCR measurement of choline acetyltransferase (FBgn0000303) expression and scRNAseq detection of both choline acetyltransferase and vesicular acetylcholine transporter (FBgn0270928). However, Raghu et al. (2013) report this neuron to be GABAergic as assessed by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA.

Axiom
annotated source: lamina monopolar neuron L4
annotated property: IAO_0000028
annotated target: L4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L4
annotated property: definition
annotated target: A lamina monopolar neuron that arborizes in the proximal lamina, forms a spreading arbor in medulla layer M2 and a small terminal arbor in M4-M5 that penetrates adjacent columns (Fischbach and Dittrich, 1989; Takemura et al., 2008; Takemura et al., 2011). In the medulla it forms presynaptic terminals in both M2 and M4-M5 with transmedullary neuron Tm2; three L4 neurons, one from the parent column and two from the posterior ones contact the same Tm2 neuron (Takemura et al., 2008; Takemura et al., 2011). It seems to be capable of both cholinergic and GABAergic neurotransmission.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0220286

Axiom
annotated source: lamina monopolar neuron L4
annotated property: hasExactSynonym
annotated target: L4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

Axiom
annotated source: lamina monopolar neuron L4
annotated property: hasExactSynonym
annotated target: monopolar laminar cell L4x
database_cross_reference: FlyBase:FBrf0054529

Axiom
annotated source: lamina monopolar neuron L4
annotated property: hasExactSynonym
annotated target: monopolar laminar cell L4y
database_cross_reference: FlyBase:FBrf0054529

lamina monopolar neuron L5
type: Class
subclass of: lamina monopolar neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature lamina monopolar neuron L5
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi4
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm3
IAO_0000028: L5
definition: A lamina monopolar neuron that hardly arborizes at all in the lamina, but forms a branched arborization in medulla layers M1 and M2 and a clump of terminals in M5. In the medulla, it forms strong reciprocal synaptic connections with monopolar lamina monopolar neuron L1 (Takemura et al., 2013). It also receives substantial input from L2 and C2 neurons and has many presynapses connecting to medullary intrinsic neurons Mi1 and Mi4, and to transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Davis et al., 2020). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10093
database_cross_reference: VFB:FBbt_00003725
has exact synonym: L5
has exact synonym: monopolar laminar cell L5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003725
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).

Axiom
annotated source: lamina monopolar neuron L5
annotated property: IAO_0000028
annotated target: L5
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina monopolar neuron L5
annotated property: definition
annotated target: A lamina monopolar neuron that hardly arborizes at all in the lamina, but forms a branched arborization in medulla layers M1 and M2 and a clump of terminals in M5. In the medulla, it forms strong reciprocal synaptic connections with monopolar lamina monopolar neuron L1 (Takemura et al., 2013). It also receives substantial input from L2 and C2 neurons and has many presynapses connecting to medullary intrinsic neurons Mi1 and Mi4, and to transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Davis et al., 2020). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina monopolar neuron L5
annotated property: hasExactSynonym
annotated target: L5
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T neuron
type: Class
subclass of: optic lobe intrinsic columnar neuron
subclass of: Restriction
  on property: overlaps
  some values from: second optic chiasma
definition: Intrinsic columnar neuron of the optic lobe that has its cell body in the posterior part of the optic lobe and a cell body fiber that bifurcates in the second optic chiasma (Fischbach and Dittrich, 1989). It has two branches, each targeting a different neuropil adjacent to the second optic chiasma (lobula, lobula plate and medulla) (Fischbach and Dittrich, 1989).
database_cross_reference: VFB:FBbt_00003726
has OBO namespace: fly_anatomy.ontology
has related synonym: T
id: FBbt:00003726
in subset: cur

Axiom
annotated source: T neuron
annotated property: definition
annotated target: Intrinsic columnar neuron of the optic lobe that has its cell body in the posterior part of the optic lobe and a cell body fiber that bifurcates in the second optic chiasma (Fischbach and Dittrich, 1989). It has two branches, each targeting a different neuropil adjacent to the second optic chiasma (lobula, lobula plate and medulla) (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410

columnar neuron T1
type: Class
subclass of: optic lobe intrinsic columnar neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
subclass of: Restriction
  on property: develops from
  some values from: immature columnar neuron T1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina intrinsic neuron Lai
IAO_0000028: T1
definition: An intrinsic columnar neuron whose cell body lies in the cortex of the medulla. The fiber of the T1 cell body branches at the medulla surface to form a T-shaped linking fiber between a bush-like arborization in the distal part of a medulla column (M1 and M2), and a bundle of climbing fibers in the equivalent column of the lamina (Fischbach and Dittrich, 1989). Synaptic connections in the lamina are exclusively postsynaptic and include a large number of connections from lamina intrinsic (amacrine) neurons (Meinertzhagen and O'Neil, 1991; Rivera-Alba et al., 2011). In the medulla, it is strongly synapsed by centrifugal neuron C3 in medulla layer M2 and lamina monopolar neuron L2 (Takemura et al., 2008; Takemura et al., 2013). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10115
database_cross_reference: VFB:FBbt_00003727
has exact synonym: T neuron T1
has exact synonym: T1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003727
in subset: cur
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for T1 (presynaptic/postsynaptic) in a single lamina cartridge for each cell type was the following: R2 (-/2), R3 (-/2), R4 (-/2), Lai (-/54), C3 (-/1) and Lawf (-/1) (Rivera-Alba et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013).

Axiom
annotated source: columnar neuron T1
annotated property: IAO_0000028
annotated target: T1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: columnar neuron T1
annotated property: definition
annotated target: An intrinsic columnar neuron whose cell body lies in the cortex of the medulla. The fiber of the T1 cell body branches at the medulla surface to form a T-shaped linking fiber between a bush-like arborization in the distal part of a medulla column (M1 and M2), and a bundle of climbing fibers in the equivalent column of the lamina (Fischbach and Dittrich, 1989). Synaptic connections in the lamina are exclusively postsynaptic and include a large number of connections from lamina intrinsic (amacrine) neurons (Meinertzhagen and O'Neil, 1991; Rivera-Alba et al., 2011). In the medulla, it is strongly synapsed by centrifugal neuron C3 in medulla layer M2 and lamina monopolar neuron L2 (Takemura et al., 2008; Takemura et al., 2013). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: columnar neuron T1
annotated property: hasExactSynonym
annotated target: T1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T2 neuron
type: Class
subclass of: CL_0008061
subclass of: T neuron
subclass of: adult cholinergic neuron
subclass of: adult GABAergic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult posterior lobula plate
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 2
IAO_0000028: T2
definition: T neuron with its soma posteriorly adjacent to the gap between the medulla and lobula plate and a cell body fiber that projects along the proximal surface of the medulla before branching in the second optic chiasm (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). One branch projects into a medulla column, where it forms a bushy, fine, arborization in medulla layer M9 and then projects through the rest of the medulla column, forming fine arborizations in M1, M2 and M5. The other branch forms a terminal arborization in lobula layer 3 that is much wider than a single column and has bleb-type terminal branches. It seems to be capable of cholinergic and GABAergic neurotransmission.
database_cross_reference: FlyBrain_NDB:10116
database_cross_reference: VFB:FBbt_00003728
has exact synonym: T neuron T2
has exact synonym: T2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003728
in subset: cur
comment: The acetylcholine neurotransmitter was assessed by co-labelling cells with a Cha-GAL4.7.4 driver (FBtp0014830) and an anti-ChAT antibody (Varija Raghu et al., 2011). The GABA neurotransmitter was assessed by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA (Raghu et al., 2013). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: T2 neuron
annotated property: IAO_0000028
annotated target: T2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T2 neuron
annotated property: definition
annotated target: T neuron with its soma posteriorly adjacent to the gap between the medulla and lobula plate and a cell body fiber that projects along the proximal surface of the medulla before branching in the second optic chiasm (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). One branch projects into a medulla column, where it forms a bushy, fine, arborization in medulla layer M9 and then projects through the rest of the medulla column, forming fine arborizations in M1, M2 and M5. The other branch forms a terminal arborization in lobula layer 3 that is much wider than a single column and has bleb-type terminal branches. It seems to be capable of cholinergic and GABAergic neurotransmission.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0212356
database_cross_reference: FlyBase:FBrf0220286
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: T2 neuron
annotated property: hasExactSynonym
annotated target: T2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T2a neuron
type: Class
subclass of: T neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult posterior lobula plate
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 3
IAO_0000028: T2a
definition: T neuron with its soma posteriorly adjacent to the gap between the medulla and lobula plate and a cell body fiber that projects along the proximal surface of the medulla before branching in the second optic chiasm (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). One branch projects into a medulla column, where it forms a bushy, fine, arborization in medulla layer M9 and then projects through the rest of the medulla column, bifurcating in medulla layer M5 and forming fine arbors throughout layers M1-4. The other branch forms a terminal arborization in lobula layer 3 that is much wider than a single column and has bleb-type terminal branches.
database_cross_reference: FlyBrain_NDB:10117
database_cross_reference: VFB:FBbt_00003729
has exact synonym: T neuron T2a
has exact synonym: T2a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003729
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: T2a neuron
annotated property: IAO_0000028
annotated target: T2a
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T2a neuron
annotated property: definition
annotated target: T neuron with its soma posteriorly adjacent to the gap between the medulla and lobula plate and a cell body fiber that projects along the proximal surface of the medulla before branching in the second optic chiasm (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). One branch projects into a medulla column, where it forms a bushy, fine, arborization in medulla layer M9 and then projects through the rest of the medulla column, bifurcating in medulla layer M5 and forming fine arbors throughout layers M1-4. The other branch forms a terminal arborization in lobula layer 3 that is much wider than a single column and has bleb-type terminal branches.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: T2a neuron
annotated property: hasExactSynonym
annotated target: T2a
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T3 neuron
type: Class
subclass of: CL_0008060
subclass of: T neuron
subclass of: adult GABAergic neuron
subclass of: adult glutamatergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult posterior lobula plate
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 3
IAO_0000028: T3
definition: T neuron with its soma posteriorly adjacent to the gap between the medulla and lobula plate and a cell body fiber that projects along the proximal surface of the medulla before branching in the second optic chiasm (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). One branch forms a bushy, fine, terminal arborization in medulla layer M9 and the other forms a terminal arborization in lobula layers 2 and 3 with mix of bleb-type and fine terminal branches (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). It seems to be capable of both glutamatergic and GABAergic neurotransmission.
database_cross_reference: FlyBrain_NDB:10183
database_cross_reference: VFB:FBbt_00003730
has exact synonym: T neuron T3
has exact synonym: T3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003730
in subset: cur
comment: The glutamate neurotransmitter was assessed by labelling cells with a vGlut[CNSIII]-GAL4 driver (FBti0129148) (Raghu and Borst, 2011). The GABA neurotransmitter was assessed by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA (Raghu et al., 2013). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: T3 neuron
annotated property: IAO_0000028
annotated target: T3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T3 neuron
annotated property: definition
annotated target: T neuron with its soma posteriorly adjacent to the gap between the medulla and lobula plate and a cell body fiber that projects along the proximal surface of the medulla before branching in the second optic chiasm (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). One branch forms a bushy, fine, terminal arborization in medulla layer M9 and the other forms a terminal arborization in lobula layers 2 and 3 with mix of bleb-type and fine terminal branches (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). It seems to be capable of both glutamatergic and GABAergic neurotransmission.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213690
database_cross_reference: FlyBase:FBrf0220286
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: T3 neuron
annotated property: hasExactSynonym
annotated target: T3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T4 neuron
type: Class
subclass of: T neuron
subclass of: secondary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult posterior lobula plate
subclass of: Restriction
  on property: develops from
  some values from: immature T4 neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer
IAO_0000028: T4
definition: T neuron with its cell body posterior to the lobula plate and a cell body fiber that projects through the lobula plate and via the second optic chiasma, with little or no arborization, to medulla layer 10 (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It forms a fine arborization in medulla layers M9 and M10 and its axon then doubles back across the second optic chiasma to form bleb-type arborizations in a single layer of the lobula plate (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T4 (and T5) neurons (Mora et al., 2018).
database_cross_reference: VFB:FBbt_00003731
has exact synonym: T neuron T4
has exact synonym: T4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003731
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. The neurotransmitter was assessed with a split-GAL4 strategy using a Chat-DBD allele (FBal0198074) (Mauss et al., 2014) and single-cell transcript profiling (Shinomiya et al., 2014).

Axiom
annotated source: T4 neuron
annotated property: IAO_0000028
annotated target: T4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T4 neuron
annotated property: definition
annotated target: T neuron with its cell body posterior to the lobula plate and a cell body fiber that projects through the lobula plate and via the second optic chiasma, with little or no arborization, to medulla layer 10 (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It forms a fine arborization in medulla layers M9 and M10 and its axon then doubles back across the second optic chiasma to form bleb-type arborizations in a single layer of the lobula plate (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T4 (and T5) neurons (Mora et al., 2018).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0224060
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0238554
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: T4 neuron
annotated property: hasExactSynonym
annotated target: T4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T4a neuron
type: Class
equivalent class: Class
  intersection of: T4 neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: lobula plate layer 1
subclass of: T4 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature T4a neuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 1
IAO_0000028: T4a
definition: T4 neuron with its lobula plate arbor in layer 1 (Fischbach and Dittrich, 1989). It responds to motion in a diagonal front-to-back direction (Henning et al., 2022).
database_cross_reference: FlyBrain_NDB:10118
database_cross_reference: VFB:FBbt_00003732
has exact synonym: T neuron T4a
has exact synonym: T4a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003732
in subset: cur

Axiom
annotated source: T4a neuron
annotated property: IAO_0000028
annotated target: T4a
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T4a neuron
annotated property: definition
annotated target: T4 neuron with its lobula plate arbor in layer 1 (Fischbach and Dittrich, 1989). It responds to motion in a diagonal front-to-back direction (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: T4a neuron
annotated property: hasExactSynonym
annotated target: T4a
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T4b neuron
type: Class
equivalent class: Class
  intersection of: T4 neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: lobula plate layer 2
subclass of: T4 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature T4b neuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 2
IAO_0000028: T4b
definition: T4 neuron with its lobula plate arbor in layer 2 (Fischbach and Dittrich, 1989). It responds to motion in a diagonal back-to-front direction (Henning et al., 2022).
database_cross_reference: VFB:FBbt_00003733
has exact synonym: T neuron T4b
has exact synonym: T4b
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003733
in subset: cur

Axiom
annotated source: T4b neuron
annotated property: IAO_0000028
annotated target: T4b
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T4b neuron
annotated property: definition
annotated target: T4 neuron with its lobula plate arbor in layer 2 (Fischbach and Dittrich, 1989). It responds to motion in a diagonal back-to-front direction (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: T4b neuron
annotated property: hasExactSynonym
annotated target: T4b
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T4c neuron
type: Class
equivalent class: Class
  intersection of: T4 neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: lobula plate layer 3
subclass of: T4 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature T4c neuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 3
IAO_0000028: T4c
definition: T4 neuron with its lobula plate arbor in layer 3 (Fischbach and Dittrich, 1989). It responds to motion in an upwards direction (Henning et al., 2022).
database_cross_reference: FlyBrain_NDB:10119
database_cross_reference: VFB:FBbt_00003734
has exact synonym: T neuron T4c
has exact synonym: T4c
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003734
in subset: cur

Axiom
annotated source: T4c neuron
annotated property: IAO_0000028
annotated target: T4c
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T4c neuron
annotated property: definition
annotated target: T4 neuron with its lobula plate arbor in layer 3 (Fischbach and Dittrich, 1989). It responds to motion in an upwards direction (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: T4c neuron
annotated property: hasExactSynonym
annotated target: T4c
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T4d neuron
type: Class
equivalent class: Class
  intersection of: T4 neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: lobula plate layer 4
subclass of: T4 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature T4d neuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 4
IAO_0000028: T4d
definition: T4 neuron with its lobula plate arbor in layer 4 (Fischbach and Dittrich, 1989). It responds to motion in a downwards direction (Henning et al., 2022).
database_cross_reference: FlyBrain_NDB:10120
database_cross_reference: VFB:FBbt_00003735
has exact synonym: T neuron T4d
has exact synonym: T4d
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003735
in subset: cur

Axiom
annotated source: T4d neuron
annotated property: IAO_0000028
annotated target: T4d
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T4d neuron
annotated property: definition
annotated target: T4 neuron with its lobula plate arbor in layer 4 (Fischbach and Dittrich, 1989). It responds to motion in a downwards direction (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: T4d neuron
annotated property: hasExactSynonym
annotated target: T4d
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T5 neuron
type: Class
subclass of: T neuron
subclass of: secondary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult lobula plate
subclass of: Restriction
  on property: develops from
  some values from: immature T5 neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer
IAO_0000028: T5
definition: T neuron with its cell body in the lobula plate cell body rind and a cell body fiber that projects through the lobula plate and via the second optic chiasma, with little or no arborization, to lobula layer 1 (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It forms a fine arborization in lobula layer 1, then its axon doubles back across the second optic chiasma to form bleb-type arborizations in a single layer of the lobula plate (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T5 (and T4) neurons (Mora et al., 2018).
database_cross_reference: VFB:FBbt_00003736
has exact synonym: T neuron T5
has exact synonym: T5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003736
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. The neurotransmitter was assessed with a split-GAL4 strategy using a Chat-DBD allele (FBal0198074) (Mauss et al., 2014) and single-cell transcript profiling (Shinomiya et al., 2014). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014).

Axiom
annotated source: T5 neuron
annotated property: IAO_0000028
annotated target: T5
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T5 neuron
annotated property: definition
annotated target: T neuron with its cell body in the lobula plate cell body rind and a cell body fiber that projects through the lobula plate and via the second optic chiasma, with little or no arborization, to lobula layer 1 (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It forms a fine arborization in lobula layer 1, then its axon doubles back across the second optic chiasma to form bleb-type arborizations in a single layer of the lobula plate (Fischbach and Dittrich, 1989; Shinomiya et al., 2019). It is a cholinergic neuron (Mauss et al., 2014; Shinomiya et al., 2014). There are a large number of these cells, which are generated from neuroblasts that amplify by symmetric division (type III) before generating the T5 (and T4) neurons (Mora et al., 2018).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0224060
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0238554
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: T5 neuron
annotated property: hasExactSynonym
annotated target: T5
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T5a neuron
type: Class
equivalent class: Class
  intersection of: T5 neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: lobula plate layer 1
subclass of: T5 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature T5a neuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 1
IAO_0000028: T5a
definition: T5 neuron with its lobula plate arbor in layer 1 (Fischbach and Dittrich, 1989). It responds to motion in a diagonal front-to-back direction (Henning et al., 2022).
database_cross_reference: FlyBrain_NDB:10121
database_cross_reference: VFB:FBbt_00003737
has exact synonym: T neuron T5a
has exact synonym: T5a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003737
in subset: cur

Axiom
annotated source: T5a neuron
annotated property: IAO_0000028
annotated target: T5a
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T5a neuron
annotated property: definition
annotated target: T5 neuron with its lobula plate arbor in layer 1 (Fischbach and Dittrich, 1989). It responds to motion in a diagonal front-to-back direction (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: T5a neuron
annotated property: hasExactSynonym
annotated target: T5a
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T5b neuron
type: Class
equivalent class: Class
  intersection of: T5 neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: lobula plate layer 2
subclass of: T5 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature T5b neuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 2
IAO_0000028: T5b
definition: T5 neuron with its lobula plate arbor in layer 2 (Fischbach and Dittrich, 1989). It responds to motion in a diagonal back-to-front direction (Henning et al., 2022).
database_cross_reference: FlyBrain_NDB:10122
database_cross_reference: VFB:FBbt_00003738
has exact synonym: T neuron T5b
has exact synonym: T5b
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003738
in subset: cur

Axiom
annotated source: T5b neuron
annotated property: IAO_0000028
annotated target: T5b
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T5b neuron
annotated property: definition
annotated target: T5 neuron with its lobula plate arbor in layer 2 (Fischbach and Dittrich, 1989). It responds to motion in a diagonal back-to-front direction (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: T5b neuron
annotated property: hasExactSynonym
annotated target: T5b
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T5c neuron
type: Class
equivalent class: Class
  intersection of: T5 neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: lobula plate layer 3
subclass of: T5 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature T5c neuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 3
IAO_0000028: T5c
definition: T5 neuron with its lobula plate arbor in layer 3 (Fischbach and Dittrich, 1989). It responds to motion in an upwards direction (Henning et al., 2022).
database_cross_reference: FlyBrain_NDB:10123
database_cross_reference: VFB:FBbt_00003739
has exact synonym: T neuron T5c
has exact synonym: T5c
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003739
in subset: cur

Axiom
annotated source: T5c neuron
annotated property: IAO_0000028
annotated target: T5c
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T5c neuron
annotated property: definition
annotated target: T5 neuron with its lobula plate arbor in layer 3 (Fischbach and Dittrich, 1989). It responds to motion in an upwards direction (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: T5c neuron
annotated property: hasExactSynonym
annotated target: T5c
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

T5d neuron
type: Class
equivalent class: Class
  intersection of: T5 neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: lobula plate layer 4
subclass of: T5 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature T5d neuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 4
IAO_0000028: T5d
definition: T5 neuron with its lobula plate arbor in layer 4 (Fischbach and Dittrich, 1989). It responds to motion in a downwards direction (Henning et al., 2022).
database_cross_reference: FlyBrain_NDB:10124
database_cross_reference: VFB:FBbt_00003740
has exact synonym: T neuron T5d
has exact synonym: T5d
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003740
in subset: cur

Axiom
annotated source: T5d neuron
annotated property: IAO_0000028
annotated target: T5d
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: T5d neuron
annotated property: definition
annotated target: T5 neuron with its lobula plate arbor in layer 4 (Fischbach and Dittrich, 1989). It responds to motion in a downwards direction (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: T5d neuron
annotated property: hasExactSynonym
annotated target: T5d
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina wide-field 1 neuron
type: Class
subclass of: lamina wide-field neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L3
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina intrinsic neuron Lai
IAO_0000028: Lawf1
definition: A lamina wide-field neuron that has a main projection that ascends via the first optic chiasm into the lamina where it is restricted to a single column for most of its length before making wide-field arborizations in the distal lamina. These neurons also arborize on the distal surface of the medulla in a circular field of about 20 columns. Several linking fibers from this arborization descend into M4 where they form a wide arborization field covering about 30-40 columns (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In the lamina, it forms numerous presynaptic connections to lamina monopolar neuron L3 and lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011).
database_cross_reference: FlyBrain_NDB:10094
database_cross_reference: VFB:FBbt_00003741
has exact synonym: LaWF1
has exact synonym: Lawf
has exact synonym: Lawf1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003741
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The identification of dendrites and axons was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP} - FBtp0021447) or a UAS-tau (P{UAS-tau-lacZ.O} - FBtp0010033) reporter, respectively (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for Lawf (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (1/1), R2 (3/-), R3 (1/-), R6 (1/-), L1 (1/-), L2 (7/-), L3 (17/-), L5 (1/-), Lai (24/-), T1 (1/-), C2 (3/-), C3 (2/-), Lawf collaterals (5) and epithelial glia (6/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: IAO_0000028
annotated target: Lawf1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: definition
annotated target: A lamina wide-field neuron that has a main projection that ascends via the first optic chiasm into the lamina where it is restricted to a single column for most of its length before making wide-field arborizations in the distal lamina. These neurons also arborize on the distal surface of the medulla in a circular field of about 20 columns. Several linking fibers from this arborization descend into M4 where they form a wide arborization field covering about 30-40 columns (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In the lamina, it forms numerous presynaptic connections to lamina monopolar neuron L3 and lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: hasExactSynonym
annotated target: LaWF1
database_cross_reference: FlyBase:FBrf0222324

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: hasExactSynonym
annotated target: Lawf
database_cross_reference: FlyBrain_NDB:10094

Axiom
annotated source: lamina wide-field 1 neuron
annotated property: hasExactSynonym
annotated target: Lawf1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

optic lobe centrifugal columnar neuron
type: Class
subclass of: optic lobe intrinsic columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
subclass of: Restriction
  on property: overlaps
  some values from: first optic chiasma
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: optic cartridge
definition: Columnar neuron whose soma lies in the cortex between the medulla and the lobula plate that extends through a single column of the medulla and lamina.
database_cross_reference: VFB:FBbt_00003742
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003742
in subset: cur

Axiom
annotated source: optic lobe centrifugal columnar neuron
annotated property: definition
annotated target: Columnar neuron whose soma lies in the cortex between the medulla and the lobula plate that extends through a single column of the medulla and lamina.
database_cross_reference: FlyBase:FBrf0049410

centrifugal neuron C2
type: Class
subclass of: optic lobe centrifugal columnar neuron
subclass of: adult GABAergic neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi1
IAO_0000028: C2
definition: Adult centrifugal neuron with arborizations in the medulla layers M1, M5/M6, M8 and M10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). In the medulla, it makes reciprocal connections to lamina monopolar neuron L1, and is presynaptic to L2 and L5, as well as medullary intrinsic neuron Mi1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10079
database_cross_reference: VFB:FBbt_00003743
has exact synonym: C2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003743
in subset: cur
comment: Pre- versus postsynaptic innervation in the proximal medulla was inferred by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).

Axiom
annotated source: centrifugal neuron C2
annotated property: IAO_0000028
annotated target: C2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: centrifugal neuron C2
annotated property: definition
annotated target: Adult centrifugal neuron with arborizations in the medulla layers M1, M5/M6, M8 and M10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). In the medulla, it makes reciprocal connections to lamina monopolar neuron L1, and is presynaptic to L2 and L5, as well as medullary intrinsic neuron Mi1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0210635
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: centrifugal neuron C2
annotated property: hasExactSynonym
annotated target: C2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

centrifugal neuron C3
type: Class
subclass of: optic lobe centrifugal columnar neuron
subclass of: adult GABAergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: columnar neuron T1
IAO_0000028: C3
definition: Adult centrifugal neuron with arborizations in medulla layers M1-2, M5, and M9-10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It forms presynapses and postsynapses in the lamina (Morante and Desplan, 2008; Rivera-Alba et al., 2011). In the medulla it is strongly presynaptic to monopolar lamina neuron L2 and columnar neuron T1, and strongly postsynaptic to L1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10080
database_cross_reference: VFB:FBbt_00003744
has exact synonym: C3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003744
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The identification of dendrites was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP} - FBtp0021447) reporter (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).

Axiom
annotated source: centrifugal neuron C3
annotated property: IAO_0000028
annotated target: C3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: centrifugal neuron C3
annotated property: definition
annotated target: Adult centrifugal neuron with arborizations in medulla layers M1-2, M5, and M9-10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It forms presynapses and postsynapses in the lamina (Morante and Desplan, 2008; Rivera-Alba et al., 2011). In the medulla it is strongly presynaptic to monopolar lamina neuron L2 and columnar neuron T1, and strongly postsynaptic to L1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0210635
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: centrifugal neuron C3
annotated property: hasExactSynonym
annotated target: C3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lamina tangential neuron
type: Class
subclass of: optic lobe tangential neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lamina
definition: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more layers of the lamina.
database_cross_reference: VFB:FBbt_00003745
has OBO namespace: fly_anatomy.ontology
has related synonym: Lat
id: FBbt:00003745
in subset: cur

Axiom
annotated source: lamina tangential neuron
annotated property: definition
annotated target: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more layers of the lamina.
database_cross_reference: FlyBase:FBrf0049410

lamina intrinsic neuron Lai
type: Class
subclass of: adult optic lobe neuron
subclass of: lamina tangential neuron
subclass of: optic lobe amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult lamina
subclass of: Restriction
  on property: develops from
  some values from: immature lamina intrinsic neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lamina
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina wide-field 1 neuron
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R6
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: columnar neuron T1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: adult lamina epithelial glial cell
subclass of: Restriction
  on property: synapses restricted to region
  some values from: lamina
IAO_0000028: Lai
definition: Intrinsic amacrine neuron of the lamina with arborizations spanning the proximal and distal lamina, whose cell body lies proximal to the lamina (Fischbach and Dittrich, 1989; Meinertzhagen and Sorra, 2001). It has extensive arborizations and forms a substantial number of presynaptic terminals with columnar neuron T1 and epithelial glia (Rivera-Alba et al., 2011). It receives strong input from each of photoreceptors R1-R6, and from lamina wide-field cells (Rivera-Alba et al., 2011). It is a glutamatergic neuron (Davis et al., 2020). There are approximately 210 of these cells on each side (Nern et al., 2025).
has broad synonym: Am
has broad synonym: amacrine cell
database_cross_reference: VFB:FBbt_00003746
has exact synonym: Lai
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003746
in subset: cur
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for Lai (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (-/36), R2 (1/39), R3 (-/39), R4 (2/37), R5 (2/35), R6 (-/40), L1 (1/-), L2 (1/-), L3 (10/-), L4 (4/2), L5 (4/-), Lai (1), T1 (54/1), C2 (1/5), C3 (1/9), Lawf (-/24) and epithelial glia (87/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: IAO_0000028
annotated target: Lai
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: definition
annotated target: Intrinsic amacrine neuron of the lamina with arborizations spanning the proximal and distal lamina, whose cell body lies proximal to the lamina (Fischbach and Dittrich, 1989; Meinertzhagen and Sorra, 2001). It has extensive arborizations and forms a substantial number of presynaptic terminals with columnar neuron T1 and epithelial glia (Rivera-Alba et al., 2011). It receives strong input from each of photoreceptors R1-R6, and from lamina wide-field cells (Rivera-Alba et al., 2011). It is a glutamatergic neuron (Davis et al., 2020). There are approximately 210 of these cells on each side (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0159582
database_cross_reference: FlyBase:FBrf0216925
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: hasBroadSynonym
annotated target: Am
database_cross_reference: FlyBase:FBrf0159582

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: hasBroadSynonym
annotated target: amacrine cell
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lamina intrinsic neuron Lai
annotated property: hasExactSynonym
annotated target: Lai
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

optic cartridge
type: Class
subclass of: synaptic neuropil segment
subclass of: Restriction
  on property: part of
  some values from: lamina
definition: Segment (column) of the lamina defined by the distal-proximal (eye to central brain) projections of photoreceptor cells of a single ommatidium.
database_cross_reference: VFB:FBbt_00003747
has OBO namespace: fly_anatomy.ontology
has related synonym: cartridge
has related synonym: lamina cartridge
id: FBbt:00003747
in subset: cur

Axiom
annotated source: optic cartridge
annotated property: definition
annotated target: Segment (column) of the lamina defined by the distal-proximal (eye to central brain) projections of photoreceptor cells of a single ommatidium.
database_cross_reference: FlyBase:FBrf0049410

medulla
type: Class
subclass of: anterior ectoderm derivative
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
subclass of: Restriction
  on property: develops from
  some values from: medulla anlage
definition: The second optic neuropil, sandwiched between the lamina and the lobula complex. It is divided into 10 layers: 1-6 make up the outer (distal) medulla, the seventh (or serpentine) layer exhibits a distinct architecture and layers 8-10 make up the inner (proximal) medulla (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00003748
has exact synonym: ME
has exact synonym: Med
has exact synonym: optic medulla
has OBO namespace: fly_anatomy.ontology
has related synonym: m
id: FBbt:00003748
in subset: BrainName
in subset: FB gloss
in subset: cur
comment: Nern et al. (2025) - FBrf0262545 say distal is M1-5 and M6-7 is central medulla.

Axiom
annotated source: medulla
annotated property: definition
annotated target: The second optic neuropil, sandwiched between the lamina and the lobula complex. It is divided into 10 layers: 1-6 make up the outer (distal) medulla, the seventh (or serpentine) layer exhibits a distinct architecture and layers 8-10 make up the inner (proximal) medulla (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0231227
database_cross_reference: VFB_vol:00003748

Axiom
annotated source: medulla
annotated property: hasExactSynonym
annotated target: ME
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: medulla
annotated property: hasExactSynonym
annotated target: Med
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: medulla
annotated property: hasExactSynonym
annotated target: optic medulla
database_cross_reference: FlyBase:FBrf0212889

outer medulla
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: plexiform medulla
definition: Layers 1-6 of the medulla.
has alternative id: FBbt:00040025
database_cross_reference: VFB:FBbt_00003749
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003749
in subset: BrainName
in subset: cur

Axiom
annotated source: outer medulla
annotated property: definition
annotated target: Layers 1-6 of the medulla.
database_cross_reference: FlyBase:FBrf0224194

medulla layer M1
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Distal-most layer of the medulla. It is defined by the distal extent of the distal lamina monopolar neuron L1 arborization (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040026
database_cross_reference: VFB:FBbt_00003750
has exact synonym: stratum M1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003750
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M1
annotated property: definition
annotated target: Distal-most layer of the medulla. It is defined by the distal extent of the distal lamina monopolar neuron L1 arborization (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M1
annotated property: hasExactSynonym
annotated target: stratum M1
database_cross_reference: FlyBase:FBrf0205531

medulla layer M2
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Second most lateral layer of the medulla. It is defined by the distal extent of the distal lamina monopolar neuron L2 arborization (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040027
database_cross_reference: VFB:FBbt_00003751
has exact synonym: L2 layer
has exact synonym: layer M2
has exact synonym: medulla layer 2
has exact synonym: stratum M2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003751
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M2
annotated property: definition
annotated target: Second most lateral layer of the medulla. It is defined by the distal extent of the distal lamina monopolar neuron L2 arborization (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M2
annotated property: hasExactSynonym
annotated target: L2 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M2
annotated property: hasExactSynonym
annotated target: layer M2
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M2
annotated property: hasExactSynonym
annotated target: stratum M2
database_cross_reference: FlyBase:FBrf0205531

medulla layer M3
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Third most lateral layer of the medulla. It is defined by the proximal border of the lamina monopolar neuron L2 arborization to that of the lamina neuron L3 terminal (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040028
database_cross_reference: VFB:FBbt_00003752
has exact synonym: L3 layer
has exact synonym: medulla layer 3
has exact synonym: stratum M3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003752
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M3
annotated property: definition
annotated target: Third most lateral layer of the medulla. It is defined by the proximal border of the lamina monopolar neuron L2 arborization to that of the lamina neuron L3 terminal (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M3
annotated property: hasExactSynonym
annotated target: L3 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M3
annotated property: hasExactSynonym
annotated target: stratum M3
database_cross_reference: FlyBase:FBrf0205531

medulla layer M4
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Fourth most lateral layer of the medulla. It corresponds to the narrow layer between the proximal end of lamina neuron L3 and the distal border of lamina neuron L1's proximal arborization (Takemura et al., 2008).
has alternative id: FBbt:00040029
database_cross_reference: VFB:FBbt_00003753
has exact synonym: L4 layer
has exact synonym: medulla layer 4
has exact synonym: stratum M4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003753
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. We use the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M4
annotated property: definition
annotated target: Fourth most lateral layer of the medulla. It corresponds to the narrow layer between the proximal end of lamina neuron L3 and the distal border of lamina neuron L1's proximal arborization (Takemura et al., 2008).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M4
annotated property: hasExactSynonym
annotated target: L4 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M4
annotated property: hasExactSynonym
annotated target: stratum M4
database_cross_reference: FlyBase:FBrf0205531

medulla layer M5
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Fifth most lateral layer of the medulla. It is defined by the lamina neuron L1's proximal arborization and contains the proximal lamina neuron L5 terminal (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040030
database_cross_reference: VFB:FBbt_00003754
has exact synonym: medulla layer 5
has exact synonym: proximal L1 layer
has exact synonym: stratum M5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003754
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M5
annotated property: definition
annotated target: Fifth most lateral layer of the medulla. It is defined by the lamina neuron L1's proximal arborization and contains the proximal lamina neuron L5 terminal (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M5
annotated property: hasExactSynonym
annotated target: proximal L1 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M5
annotated property: hasExactSynonym
annotated target: stratum M5
database_cross_reference: FlyBase:FBrf0205531

medulla layer M6
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: outer medulla
definition: Sixth most lateral layer of the medulla, immediately lateral to the serpentine layer. It lies between the lamina neuron L1's arborization and the serpentine layer (Fischbach and Dittrich, 1989).
has alternative id: FBbt:00040031
database_cross_reference: VFB:FBbt_00003755
has exact synonym: R7 layer
has exact synonym: medulla layer 6
has exact synonym: stratum M6
has OBO namespace: fly_anatomy.ontology
has related synonym: R7 recipient layer
id: FBbt:00003755
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla layer M6
annotated property: definition
annotated target: Sixth most lateral layer of the medulla, immediately lateral to the serpentine layer. It lies between the lamina neuron L1's arborization and the serpentine layer (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M6
annotated property: hasExactSynonym
annotated target: R7 layer
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla layer M6
annotated property: hasExactSynonym
annotated target: stratum M6
database_cross_reference: FlyBase:FBrf0205531

Axiom
annotated source: medulla layer M6
annotated property: hasRelatedSynonym
annotated target: R7 recipient layer
database_cross_reference: FlyBase:FBrf0209317

medulla serpentine layer
type: Class
subclass of: medulla layer
definition: A major layer of extensive tangential fibers in the medulla, many of which project via the posterior optic commissure to the opposite medulla. It is the 7th most lateral layer of the medulla.
database_cross_reference: VFB:FBbt_00003756
has exact synonym: SPL
has exact synonym: medulla layer 7
has OBO namespace: fly_anatomy.ontology
has related synonym: medulla layer M7
id: FBbt:00003756
in subset: BrainName
in subset: cur

Axiom
annotated source: medulla serpentine layer
annotated property: definition
annotated target: A major layer of extensive tangential fibers in the medulla, many of which project via the posterior optic commissure to the opposite medulla. It is the 7th most lateral layer of the medulla.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0065419
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla serpentine layer
annotated property: hasExactSynonym
annotated target: SPL
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

inner medulla
type: Class
subclass of: medulla layer
definition: Layers 8-10 of the medulla.
database_cross_reference: VFB:FBbt_00003757
has exact synonym: MEI
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003757
in subset: BrainName
in subset: cur

Axiom
annotated source: inner medulla
annotated property: definition
annotated target: Layers 8-10 of the medulla.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: inner medulla
annotated property: hasExactSynonym
annotated target: MEI
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

medulla layer M8
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: inner medulla
definition: Lateral-most layer of the inner medulla, immediately medial to the serpentine layer.
has alternative id: FBbt:00040022
database_cross_reference: VFB:FBbt_00003758
has exact synonym: medulla layer 8
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003758
in subset: cur

Axiom
annotated source: medulla layer M8
annotated property: definition
annotated target: Lateral-most layer of the inner medulla, immediately medial to the serpentine layer.
database_cross_reference: FlyBase:FBrf0224194

medulla layer M9
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: inner medulla
definition: Middle layer of the inner medulla.
has alternative id: FBbt:00040023
database_cross_reference: VFB:FBbt_00003759
has exact synonym: medulla layer 9
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003759
in subset: cur

Axiom
annotated source: medulla layer M9
annotated property: definition
annotated target: Middle layer of the inner medulla.
database_cross_reference: FlyBase:FBrf0224194

medulla layer M10
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: inner medulla
definition: Inner-most layer of the medulla. Practically it is defined by the height of the T4 neuron terminal arborizations.
has alternative id: FBbt:00040024
database_cross_reference: VFB:FBbt_00003760
has exact synonym: T4 layer
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003760
in subset: cur

Axiom
annotated source: medulla layer M10
annotated property: definition
annotated target: Inner-most layer of the medulla. Practically it is defined by the height of the T4 neuron terminal arborizations.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: medulla layer M10
annotated property: hasExactSynonym
annotated target: T4 layer
database_cross_reference: FlyBase:FBrf0049410

distal medullary amacrine neuron
type: Class
subclass of: adult optic lobe neuron
subclass of: optic lobe amacrine neuron
subclass of: medulla intrinsic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
IAO_0000028: Dm
definition: An amacrine neuron that is intrinsic to the medulla, whose soma is located in the cortex of the medulla and that branches and arborizes in the distal medulla. These neurons project through the distal surface of the medulla, to form wide (sometimes very wide) terminal arborizations mainly or completely restricted to a single layer of the medulla.
database_cross_reference: VFB:FBbt_00003767
has exact synonym: Dm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003767
in subset: cur

Axiom
annotated source: distal medullary amacrine neuron
annotated property: definition
annotated target: An amacrine neuron that is intrinsic to the medulla, whose soma is located in the cortex of the medulla and that branches and arborizes in the distal medulla. These neurons project through the distal surface of the medulla, to form wide (sometimes very wide) terminal arborizations mainly or completely restricted to a single layer of the medulla.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: distal medullary amacrine neuron
annotated property: hasExactSynonym
annotated target: Dm
has synonym type: VFB SYMBOL

distal medullary amacrine neuron Dm1
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
IAO_0000028: Dm1
definition: Distal medullary wide-field amacrine neuron whose cell body is located in the anterior region of the cell body rind of the medulla. It branches extensively at the distal surface of the medulla forming a moderately broad arbor with each branch making a distinctive bouton-like terminal in the region between M1 and M2 (in the same sublayer as Dm18, and more proximal than Dm9 and Dm10 in M1), from which short, fine terminal branches project (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). The arbor varies in shape between cells, covering around 20-30 columns, but with these areas overlapping. The size of the terminals of Dm1 is smaller than those of Dm18. There are around 40 Dm1 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBrain_NDB:10081
database_cross_reference: VFB:FBbt_00003768
has exact synonym: Dm1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003768
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: distal medullary amacrine neuron Dm1
annotated property: IAO_0000028
annotated target: Dm1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm1
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron whose cell body is located in the anterior region of the cell body rind of the medulla. It branches extensively at the distal surface of the medulla forming a moderately broad arbor with each branch making a distinctive bouton-like terminal in the region between M1 and M2 (in the same sublayer as Dm18, and more proximal than Dm9 and Dm10 in M1), from which short, fine terminal branches project (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). The arbor varies in shape between cells, covering around 20-30 columns, but with these areas overlapping. The size of the terminals of Dm1 is smaller than those of Dm18. There are around 40 Dm1 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0244935

Axiom
annotated source: distal medullary amacrine neuron Dm1
annotated property: hasExactSynonym
annotated target: Dm1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

distal medullary amacrine neuron Dm2
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm2
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M6
IAO_0000028: Dm2
definition: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. It terminates with a small bushy arbor with mixed terminal morphology in layers M3-M6B. The arbors in M6B extend into neighboring columns on the dorsal side. The small arbors cover 2 columns in M6 and one in the other layers. It is cholinergic (Konstantinides et al., 2022).
database_cross_reference: FlyBrain_NDB:10082
database_cross_reference: VFB:FBbt_00003769
has exact synonym: Dm2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003769
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: distal medullary amacrine neuron Dm2
annotated property: IAO_0000028
annotated target: Dm2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm2
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. It terminates with a small bushy arbor with mixed terminal morphology in layers M3-M6B. The arbors in M6B extend into neighboring columns on the dorsal side. The small arbors cover 2 columns in M6 and one in the other layers. It is cholinergic (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0253187

Axiom
annotated source: distal medullary amacrine neuron Dm2
annotated property: hasExactSynonym
annotated target: Dm2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

distal medullary amacrine neuron Dm3
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla sublayer M3A
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla sublayer M3A
IAO_0000028: Dm3
definition: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. It projects asymmetrically along layers M2 and M3A forming mixed morphology arborizations (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). The arborization is proximal to that of Dm15 in M2 and distal to Dm4, Dm12 and Dm20 in M3B. Its arbor has a distinct narrow and elongated shape, covering one column wide and 10 columns long. The arbors overlap significantly between cells, aligning with rows of medulla columns, and extending in one of two orthogonal orientations. It is a glutamatergic neuron (Raghu and Borst, 2011). There are two subtypes with different dendrite orientation, synaptic partners and gene expression (Ozel et al., 2021).
database_cross_reference: FlyBrain_NDB:10083
database_cross_reference: VFB:FBbt_00003770
has exact synonym: Dm3
has exact synonym: Dm3 line amacrine cell
has exact synonym: Dm3 line amacrine neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003770
in subset: cur
comment: The neurotransmitter was assessed by labelling cells with a vGlut[CNSIII]-GAL4 driver (FBti0129148) (Raghu and Borst, 2011). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: IAO_0000028
annotated target: Dm3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. It projects asymmetrically along layers M2 and M3A forming mixed morphology arborizations (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). The arborization is proximal to that of Dm15 in M2 and distal to Dm4, Dm12 and Dm20 in M3B. Its arbor has a distinct narrow and elongated shape, covering one column wide and 10 columns long. The arbors overlap significantly between cells, aligning with rows of medulla columns, and extending in one of two orthogonal orientations. It is a glutamatergic neuron (Raghu and Borst, 2011). There are two subtypes with different dendrite orientation, synaptic partners and gene expression (Ozel et al., 2021).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213690
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: hasExactSynonym
annotated target: Dm3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: hasExactSynonym
annotated target: Dm3 line amacrine cell
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: distal medullary amacrine neuron Dm3
annotated property: hasExactSynonym
annotated target: Dm3 line amacrine neuron
database_cross_reference: FlyBase:FBrf0262545

distal medullary amacrine neuron Dm4
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla sublayer M3B
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla sublayer M3B
IAO_0000028: Dm4
definition: Distal medullary wide-field amacrine neuron whose cell body is located in the anterior region of the cell body rind of the medulla. The main neurite extends into M6, and then turns back to arborize in the boundary between M5 and M6, and in M3B, with mixed morphology arborizations. The arbor varies in shape between cells, covering around 21 columns, but with these areas tiling. It is located in a central position in the column, surrounded by the terminal of photoreceptors R7 and R8, with the cell boundaries following the column boundaries. There are around 40 Dm4 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBrain_NDB:10084
database_cross_reference: VFB:FBbt_00003771
has exact synonym: Dm4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003771
in subset: cur
comment: Classified as columnar based on first stretch of main projection being limited to a single column, but as it then bends and projects along the plane of M5/M6 where it arborizes, this is clearly an edge case. Pre- versus postsynaptic innervation were judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: distal medullary amacrine neuron Dm4
annotated property: IAO_0000028
annotated target: Dm4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm4
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron whose cell body is located in the anterior region of the cell body rind of the medulla. The main neurite extends into M6, and then turns back to arborize in the boundary between M5 and M6, and in M3B, with mixed morphology arborizations. The arbor varies in shape between cells, covering around 21 columns, but with these areas tiling. It is located in a central position in the column, surrounded by the terminal of photoreceptors R7 and R8, with the cell boundaries following the column boundaries. There are around 40 Dm4 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0244935

Axiom
annotated source: distal medullary amacrine neuron Dm4
annotated property: hasExactSynonym
annotated target: Dm4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

medulla intrinsic columnar neuron
type: Class
equivalent class: Class
  intersection of: optic lobe intrinsic columnar neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: medulla
subclass of: optic lobe intrinsic columnar neuron
subclass of: medulla intrinsic neuron
subclass of: medulla columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
IAO_0000028: Mi
definition: A columnar neuron that is intrinsic to the medulla, connecting distal and proximal layers (Fischbach and Dittrich, 1989; Kind et al., 2021). It has its soma in the cell body rind of the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: VFB:FBbt_00003775
has exact synonym: Mi
has exact synonym: medulla intrinsic cell
has exact synonym: medullary intrinsic columnar neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003775
in subset: cur

Axiom
annotated source: medulla intrinsic columnar neuron
annotated property: IAO_0000028
annotated target: Mi
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: medulla intrinsic columnar neuron
annotated property: definition
annotated target: A columnar neuron that is intrinsic to the medulla, connecting distal and proximal layers (Fischbach and Dittrich, 1989; Kind et al., 2021). It has its soma in the cell body rind of the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla intrinsic columnar neuron
annotated property: hasExactSynonym
annotated target: Mi
database_cross_reference: FlyBase:FBrf0252485
has synonym type: VFB SYMBOL

Axiom
annotated source: medulla intrinsic columnar neuron
annotated property: hasExactSynonym
annotated target: medulla intrinsic cell
database_cross_reference: FlyBase:FBrf0252485

medulla intrinsic neuron Mi1
type: Class
subclass of: medulla intrinsic columnar neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: optic lobe narrow field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M10
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T4 neuron
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm3
IAO_0000028: Mi1
definition: Unicolumnar medullary intrinsic neuron with bushy, fine arborizations in medulla layers M1, M5 and M9-10 (Fischbach and Dittrich, 1989; Kind et al., 2021). The projection of this neuron branches at the inner-face of the medulla to form two to three varicose recurrent terminal specializations that extend back up to the inner border of layer M8 (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In central (non-dorsal margin) columns it receives input from an R8 photoreceptor cell, but connections are substantially weaker in dorsal margin columns (Kind et al., 2021). Pre-synaptic terminals are present mainly in medulla layers M9-M10, but also in all other layers where neurites extend laterally (Pankova and Borst, 2017). It receives input from lamina monopolar neurons L1 and L5 and centrifugal neuron C2 (Takemura et al., 2013). It outputs to T4 neurons and transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Hasegawa et al., 2011; Pankova and Borst, 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10097
database_cross_reference: VFB:FBbt_00003776
has exact synonym: Mi1
has exact synonym: medullary intrinsic neuron 1
has exact synonym: medullary intrinsic neuron Mi1
has OBO namespace: fly_anatomy.ontology
has related synonym: Sut
has related synonym: small field unilateral tristratified neuron
id: FBbt:00003776
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The neurotransmitter was assessed by labelling cells with an anti-ChAT antibody (Hasegawa et al., 2011). The morphology of the terminals was judged from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity and morphology in the medulla were assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013).

Axiom
annotated source: medulla intrinsic neuron Mi1
annotated property: IAO_0000028
annotated target: Mi1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: medulla intrinsic neuron Mi1
annotated property: definition
annotated target: Unicolumnar medullary intrinsic neuron with bushy, fine arborizations in medulla layers M1, M5 and M9-10 (Fischbach and Dittrich, 1989; Kind et al., 2021). The projection of this neuron branches at the inner-face of the medulla to form two to three varicose recurrent terminal specializations that extend back up to the inner border of layer M8 (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). In central (non-dorsal margin) columns it receives input from an R8 photoreceptor cell, but connections are substantially weaker in dorsal margin columns (Kind et al., 2021). Pre-synaptic terminals are present mainly in medulla layers M9-M10, but also in all other layers where neurites extend laterally (Pankova and Borst, 2017). It receives input from lamina monopolar neurons L1 and L5 and centrifugal neuron C2 (Takemura et al., 2013). It outputs to T4 neurons and transmedullary neuron Tm3a (Takemura et al., 2013). It is a cholinergic neuron (Hasegawa et al., 2011; Pankova and Borst, 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213020
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0235353
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: medulla intrinsic neuron Mi1
annotated property: hasExactSynonym
annotated target: Mi1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

medulla intrinsic neuron Mi4
type: Class
subclass of: medulla intrinsic columnar neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult GABAergic neuron
subclass of: optic lobe narrow field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature medulla intrinsic neuron Mi4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M8
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R8
IAO_0000028: Mi4
definition: Medulla intrinsic narrow field neuron with both fine and bleb-type arborizations in medulla layers M1, M2, M3 and M8, but with only fine arborizations in medulla layers M4 and M5, and only bleb-type arborizations in medulla layer M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). It receives input from the lamina monopolar neuron L5 and photoreceptor R8 (Takemura et al., 2013). It is a GABAergic neuron (Takemura et al., 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10103
database_cross_reference: VFB:FBbt_00003779
has exact synonym: Mi4
has exact synonym: medullary intrinsic neuron Mi4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003779
in subset: cur
comment: Raghu and Borst (2011) identified this as glutamatergic using a vGlut[CNSIII]-GAL4 driver (FBti0129148), but vGlut antibody staining performed by Takemura et al. (2017) was not strong compared to neighboring cells, whereas GAD1 staining was strong. Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013). Kind et al. (2020) say that it is not contacted by R7/R8 in the DRA, but not clear whether Mi4 is present in the DRA.

Axiom
annotated source: medulla intrinsic neuron Mi4
annotated property: IAO_0000028
annotated target: Mi4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: medulla intrinsic neuron Mi4
annotated property: definition
annotated target: Medulla intrinsic narrow field neuron with both fine and bleb-type arborizations in medulla layers M1, M2, M3 and M8, but with only fine arborizations in medulla layers M4 and M5, and only bleb-type arborizations in medulla layer M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). It receives input from the lamina monopolar neuron L5 and photoreceptor R8 (Takemura et al., 2013). It is a GABAergic neuron (Takemura et al., 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213690
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: medulla intrinsic neuron Mi4
annotated property: hasExactSynonym
annotated target: Mi4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

medulla intrinsic neuron Mi9
type: Class
subclass of: medulla intrinsic columnar neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: optic lobe narrow field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature medulla intrinsic neuron Mi9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M10
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L3
IAO_0000028: Mi9
definition: Medulla intrinsic narrow field neuron with a bushy mix of bleb-type and fine terminal arborization in layers M2, M3 and M4 and in the lower medulla layers M9-M10 (Fischbach and Dittrich, 1989; Kind et al., 2021). It establishes pre- and post-synaptic connections in both the inner and outer medulla layers (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). It receives input from lamina monopolar neuron L3 (Takemura et al., 2013). It is glutamatergic (Takemura et al., 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10108
database_cross_reference: VFB:FBbt_00003784
has exact synonym: Mi9
has exact synonym: medullary intrinsic neuron Mi9
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003784
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The identification of dendrites and axons was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP} - FBtp0021447) or a UAS-tau (P{UAS-tau-lacZ.O} - FBtp0010033) reporter, respectively (Morante and Desplan, 2008). Connectivity in the medulla was extrapolated from serial EM from 7 columns (Takemura et al., 2013).

Axiom
annotated source: medulla intrinsic neuron Mi9
annotated property: IAO_0000028
annotated target: Mi9
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: medulla intrinsic neuron Mi9
annotated property: definition
annotated target: Medulla intrinsic narrow field neuron with a bushy mix of bleb-type and fine terminal arborization in layers M2, M3 and M4 and in the lower medulla layers M9-M10 (Fischbach and Dittrich, 1989; Kind et al., 2021). It establishes pre- and post-synaptic connections in both the inner and outer medulla layers (Fischbach and Dittrich, 1989; Morante and Desplan, 2008). It receives input from lamina monopolar neuron L3 (Takemura et al., 2013). It is glutamatergic (Takemura et al., 2017). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0235606
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: medulla intrinsic neuron Mi9
annotated property: hasExactSynonym
annotated target: Mi9
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron
type: Class
subclass of: optic lobe intrinsic columnar neuron
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0000634
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
subclass of: Restriction
  on property: fasciculates with
  some values from: second optic chiasma
subclass of: Restriction
  on property: overlaps
  some values from: medulla
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula
IAO_0000028: Tm
definition: An intrinsic columnar neuron of the optic lobe whose cell body lies in the distal cortex of the medulla and that projects through the medulla and optic chiasm into the lobula. All neurons arborize in the lobula and most, but not all, in the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: VFB:FBbt_00003788
has exact synonym: Tm
has exact synonym: Tm neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003788
in subset: cur

Axiom
annotated source: transmedullary neuron
annotated property: IAO_0000028
annotated target: Tm
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron
annotated property: definition
annotated target: An intrinsic columnar neuron of the optic lobe whose cell body lies in the distal cortex of the medulla and that projects through the medulla and optic chiasm into the lobula. All neurons arborize in the lobula and most, but not all, in the medulla (Fischbach and Dittrich, 1989).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652

Axiom
annotated source: transmedullary neuron
annotated property: hasExactSynonym
annotated target: Tm
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm1
type: Class
subclass of: narrow field transmedullary neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T5 neuron
IAO_0000028: Tm1
definition: Transmedullary narrow field neuron that terminates in lobula layer 1 with a bleb-type terminal arborization and that has fine arborizations in medulla layer M2 and bleb-type arborizations in M3 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). In the medulla, it receives strong synaptic input from lamina monopolar neuron L2 (Takemura et al., 2011; Takemura et al., 2013). It outputs onto T5 neurons (Shinomiya et al., 2019). It is a cholinergic neuron (Varija Raghu et al., 2011; Shinomiya et al., 2014). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10132
database_cross_reference: VFB:FBbt_00003789
has exact synonym: Tm1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003789
in subset: cur
comment: The neurotransmitter was assessed by co-labelling cells with a P{Cha-GAL4.7.4} driver (FBtp0014830) and an anti-ChAT antibody (Varija Raghu et al., 2011; Shinomiya et al., 2014). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014). Connectivity in the entire optic lobe was also assessed by EM (Shinomiya et al., 2019).

Axiom
annotated source: transmedullary neuron Tm1
annotated property: IAO_0000028
annotated target: Tm1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm1
annotated property: definition
annotated target: Transmedullary narrow field neuron that terminates in lobula layer 1 with a bleb-type terminal arborization and that has fine arborizations in medulla layer M2 and bleb-type arborizations in M3 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). In the medulla, it receives strong synaptic input from lamina monopolar neuron L2 (Takemura et al., 2011; Takemura et al., 2013). It outputs onto T5 neurons (Shinomiya et al., 2019). It is a cholinergic neuron (Varija Raghu et al., 2011; Shinomiya et al., 2014). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0212356
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0241236
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm1
annotated property: hasExactSynonym
annotated target: Tm1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm2
type: Class
subclass of: narrow field transmedullary neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L4
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T5 neuron
IAO_0000028: Tm2
definition: Transmedullary narrow field neuron that has its main dendritic arborization in medulla layer M2 (Ting et al., 2014), where it receives input from lamina monopolar neuron L2 (Takemura et al., 2011), and additional postsynaptic terminals in M4-M5, where it receives input from lamina monopolar neuron L4 (Takemura et al., 2011). It has presynaptic terminals in layers M3, M4 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). Its axon follows the posterior edge of its cognate medulla column (Ting et al., 2014), then crosses the second optic chiasma to terminate in lobula layers 1 and 2 (Fischbach and Dittrich, 1989). In layer 1 it outputs to T5 neurons (Shinomiya et al., 2014). It is a cholinergic neuron (Varija Raghu et al., 2011; Gao et al., 2008; Takemura et al., 2011). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10144
database_cross_reference: VFB:FBbt_00003790
has exact synonym: Tm2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003790
in subset: cur
comment: The neurotransmitter has been assessed by co-labelling cells with a P{Cha-GAL4.7.4} driver (FBtp0014830) and an anti-ChAT antibody (Varija Raghu et al., 2011), by using a Cha-GAL4.DBD (FBtp002350) (Gao et al., 2008) and by neurotransmitter was assessed by single cell RT-PCR measurement of choline acetyltransferase (FBgn0000303) expression (Takemura et al., 2011). Connectivity in the medulla was extrapolated from serial EM of 3 columns from a single sample (Takemura et al., 2008) or from 7 columns (Takemura et al., 2013). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014).

Axiom
annotated source: transmedullary neuron Tm2
annotated property: IAO_0000028
annotated target: Tm2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm2
annotated property: definition
annotated target: Transmedullary narrow field neuron that has its main dendritic arborization in medulla layer M2 (Ting et al., 2014), where it receives input from lamina monopolar neuron L2 (Takemura et al., 2011), and additional postsynaptic terminals in M4-M5, where it receives input from lamina monopolar neuron L4 (Takemura et al., 2011). It has presynaptic terminals in layers M3, M4 and M9 (Fischbach and Dittrich, 1989; Takemura et al., 2011). Its axon follows the posterior edge of its cognate medulla column (Ting et al., 2014), then crosses the second optic chiasma to terminate in lobula layers 1 and 2 (Fischbach and Dittrich, 1989). In layer 1 it outputs to T5 neurons (Shinomiya et al., 2014). It is a cholinergic neuron (Varija Raghu et al., 2011; Gao et al., 2008; Takemura et al., 2011). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0212356
database_cross_reference: FlyBase:FBrf0217052
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0224196
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm2
annotated property: hasExactSynonym
annotated target: Tm2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm3
type: Class
subclass of: CL_0008061
subclass of: narrow field transmedullary neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: adult GABAergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T4 neuron
IAO_0000028: Tm3
definition: Transmedullary narrow field neuron that terminates in lobula layers 1 and 4 with bleb-like terminal arborizations. It has fine arborizations in medulla layers M1, M4, and M5, and has bleb-type arborization in medulla layers M1, M4, M9 and M10 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). Pre-synaptic terminals are present mainly in medulla layers M9-M10, but also in all other layers where neurites extend laterally (Pankova and Borst, 2017). It receives input from lamina monopolar neuron L1 and L5 and medullary intrinsic neuron Mi1 and it outputs to T4 neurons (Takemura et al., 2013). It seems to be capable of both cholinergic (Pankova & Borst, 2017) and GABAergic (Raghu et al., 2013) neurotransmission.
database_cross_reference: FlyBrain_NDB:10153
database_cross_reference: VFB:FBbt_00003791
has exact synonym: Tm3
has exact synonym: Tm3a
has exact synonym: transmedullary neuron Tm3a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003791
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. The neurotransmitter was assessed to be GABA by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA (Raghu et al., 2013). Connectivity in the medulla was assessed by electron microscopy reconstruction from 7 columns (Takemura et al., 2013). Neuron was assessed to be cholinergic based on anti-HA antibody detection of HA-tagged VAChT expression (Pankova & Borst, 2017).

Axiom
annotated source: transmedullary neuron Tm3
annotated property: IAO_0000028
annotated target: Tm3
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: transmedullary neuron Tm3
annotated property: definition
annotated target: Transmedullary narrow field neuron that terminates in lobula layers 1 and 4 with bleb-like terminal arborizations. It has fine arborizations in medulla layers M1, M4, and M5, and has bleb-type arborization in medulla layers M1, M4, M9 and M10 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). Pre-synaptic terminals are present mainly in medulla layers M9-M10, but also in all other layers where neurites extend laterally (Pankova and Borst, 2017). It receives input from lamina monopolar neuron L1 and L5 and medullary intrinsic neuron Mi1 and it outputs to T4 neurons (Takemura et al., 2013). It seems to be capable of both cholinergic (Pankova & Borst, 2017) and GABAergic (Raghu et al., 2013) neurotransmission.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0213020
database_cross_reference: FlyBase:FBrf0220286
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0235353

Axiom
annotated source: transmedullary neuron Tm3
annotated property: hasExactSynonym
annotated target: Tm3
database_cross_reference: FlyBase:FBrf0049410
has synonym type: VFB SYMBOL

Axiom
annotated source: transmedullary neuron Tm3
annotated property: hasExactSynonym
annotated target: Tm3a
database_cross_reference: FlyBase:FBrf0213020

Axiom
annotated source: transmedullary neuron Tm3
annotated property: hasExactSynonym
annotated target: transmedullary neuron Tm3a
database_cross_reference: FlyBase:FBrf0213020

transmedullary neuron Tm4
type: Class
subclass of: CL_0008061
subclass of: narrow field transmedullary neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: adult GABAergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: centrifugal neuron C3
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T5 neuron
IAO_0000028: Tm4
definition: Transmedullary narrow field neuron that terminates in lobula layers 1, 2 and 4 with bleb-type arborizations, and with fine arborizations in layer 3. It displays fine arborizations in medulla layers M2, M3, M4 and M9, and has bleb-type arborizations in layers M2, M4, and M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). In the medulla, receives input from lamina monopolar neuron L2 and centrifugal neuron C3 (Takemura et al., 2013). In lobula layer 1, it outputs to T5 neurons (Shinomiya et al., 2014). It seems to be capable of both cholinergic and GABAergic neurotransmission. There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10155
database_cross_reference: VFB:FBbt_00003792
has exact synonym: Tm4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003792
in subset: cur
comment: The acetylcholine neurotransmitter was assessed by co-labelling cells with a Cha-GAL4.7.4 driver (FBtp0014830) and an anti-ChAT antibody (Varija Raghu et al., 2011), and by scRNAseq detection of choline acetyltransferase (FBgn0000303) and vesicular acetylcholine transporter (FBgn0270928) expression (Davis et al., 2020). The GABA neurotransmitter was assessed by the intersection of the expression of the VGAT-GAL4 driver (FBtp0069181) and an antibody against GABA (Raghu et al., 2013). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM from 7 columns (Takemura et al., 2013). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014).

Axiom
annotated source: transmedullary neuron Tm4
annotated property: IAO_0000028
annotated target: Tm4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm4
annotated property: definition
annotated target: Transmedullary narrow field neuron that terminates in lobula layers 1, 2 and 4 with bleb-type arborizations, and with fine arborizations in layer 3. It displays fine arborizations in medulla layers M2, M3, M4 and M9, and has bleb-type arborizations in layers M2, M4, and M9 (Morante and Desplan, 2008; Fischbach and Dittrich, 1989). In the medulla, receives input from lamina monopolar neuron L2 and centrifugal neuron C3 (Takemura et al., 2013). In lobula layer 1, it outputs to T5 neurons (Shinomiya et al., 2014). It seems to be capable of both cholinergic and GABAergic neurotransmission. There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0212356
database_cross_reference: FlyBase:FBrf0220286
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm4
annotated property: hasExactSynonym
annotated target: Tm4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm5
type: Class
subclass of: transmedullary neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 5
IAO_0000028: Tm5
definition: Transmedullary neuron that terminates in lobula layer 5 with bleb-type arborizations. It displays fine arborizations in medulla layers M3 and M6 and other, depending on the subtype. It has bleb-type terminals in layers M6 and M8. It has three subtypes.
database_cross_reference: FlyBrain_NDB:10157
database_cross_reference: VFB:FBbt_00003793
has exact synonym: Tm5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003793
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. In these figures, the neuron has characteristics of the three Tm5 subtypes.

Axiom
annotated source: transmedullary neuron Tm5
annotated property: IAO_0000028
annotated target: Tm5
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm5
annotated property: definition
annotated target: Transmedullary neuron that terminates in lobula layer 5 with bleb-type arborizations. It displays fine arborizations in medulla layers M3 and M6 and other, depending on the subtype. It has bleb-type terminals in layers M6 and M8. It has three subtypes.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0224070

Axiom
annotated source: transmedullary neuron Tm5
annotated property: hasExactSynonym
annotated target: Tm5
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm9
type: Class
subclass of: narrow field transmedullary neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm9
subclass of: Restriction
  on property: expresses
  some values from: FBgn0004666
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: T5 neuron
IAO_0000028: Tm9
definition: Transmedullary narrow field neuron that has most of its dendritic arborization in medulla layers M2 and M3, with some extensions into M1, M4 and M5 (Gao et al., 2008; Ting et al., 2014), and presynapses in M3 (Gao et al., 2008). Its axon follows the posterior edge of its cognate medulla column (Ting et al., 2014), then crosses in the second optic chiasma and terminates in lobula layer 1 (Fischbach and Dittrich, 1989; Ting et al., 2014), where it outputs to T5 neurons (Shinomiya et al., 2014). It is a cholinergic neuron (Gao et al., 2008; Shinomiya et al., 2014). It expresses the transcription factor sim (Ozel et al., 2021). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10163
database_cross_reference: VFB:FBbt_00003797
has exact synonym: Tm9
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003797
in subset: cur
comment: Neurotransmitter was assessed using a cha-GAL4DBD driver (Gao et al., 2008), single-cell transcript profiling and immunohistochemistry (Shinomiya et al., 2014). Connectivity in the lobula was assessed by serial section electron microscopy of a single column (Shinomiya et al., 2014).

Axiom
annotated source: transmedullary neuron Tm9
annotated property: IAO_0000028
annotated target: Tm9
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm9
annotated property: definition
annotated target: Transmedullary narrow field neuron that has most of its dendritic arborization in medulla layers M2 and M3, with some extensions into M1, M4 and M5 (Gao et al., 2008; Ting et al., 2014), and presynapses in M3 (Gao et al., 2008). Its axon follows the posterior edge of its cognate medulla column (Ting et al., 2014), then crosses in the second optic chiasma and terminates in lobula layer 1 (Fischbach and Dittrich, 1989; Ting et al., 2014), where it outputs to T5 neurons (Shinomiya et al., 2014). It is a cholinergic neuron (Gao et al., 2008; Shinomiya et al., 2014). It expresses the transcription factor sim (Ozel et al., 2021). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0224196
database_cross_reference: FlyBase:FBrf0225094
database_cross_reference: FlyBase:FBrf0247762
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm9
annotated property: hasExactSynonym
annotated target: Tm9
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm20
type: Class
subclass of: narrow field transmedullary neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm20
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M8
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina monopolar neuron L3
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R8
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lobula intrinsic neuron Li4
IAO_0000028: Tm20
definition: Transmedullary neuron that has dendritic arborization in medulla layers M1-M3, as well as presynaptic sites in M8 (Fischbach and Dittrich, 1989; Gao et al., 2008). In the medulla, it spans just one column (Kind et al., 2021), and receives input from lamina monopolar neuron L3 (Takemura et al., 2013) and an R8 photoreceptor (Kind et al., 2021). Its axon follows the anterior edge of its cognate medulla column (Ting et al., 2014), then crosses the second optic chiasma and projects to lobula layer 5 (Fischbach and Dittrich, 1989; Gao et al., 2008). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It is a cholinergic neuron (Gao et al., 2008). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBrain_NDB:10145
database_cross_reference: VFB:FBbt_00003808
has exact synonym: Tm20
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003808
in subset: cur
comment: Connectivity in the medulla based on EM (Takemura et al., 2013; Kind et al., 2021). Connectivity in the lobula was assessed by GRASP and double-labeling EM (Lin et al., 2016). Neurotransmitter was assessed using a cha-GAL4DBD driver (Gao et al., 2008).

Axiom
annotated source: transmedullary neuron Tm20
annotated property: IAO_0000028
annotated target: Tm20
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm20
annotated property: definition
annotated target: Transmedullary neuron that has dendritic arborization in medulla layers M1-M3, as well as presynaptic sites in M8 (Fischbach and Dittrich, 1989; Gao et al., 2008). In the medulla, it spans just one column (Kind et al., 2021), and receives input from lamina monopolar neuron L3 (Takemura et al., 2013) and an R8 photoreceptor (Kind et al., 2021). Its axon follows the anterior edge of its cognate medulla column (Ting et al., 2014), then crosses the second optic chiasma and projects to lobula layer 5 (Fischbach and Dittrich, 1989; Gao et al., 2008). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It is a cholinergic neuron (Gao et al., 2008). There is usually one of these cells per optic column (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0224196
database_cross_reference: FlyBase:FBrf0230403
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm20
annotated property: hasExactSynonym
annotated target: Tm20
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary Y neuron
type: Class
subclass of: transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary Y neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula plate
IAO_0000028: TmY
definition: An intrinsic columnar neuron of the optic lobe whose cell body lies in the distal cortex of the medulla and that arborizes in the medulla and branches in the second optic chiasm with one branch innervating the lobula and the other the lobula plate.
database_cross_reference: VFB:FBbt_00003817
has exact synonym: TmY
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003817
in subset: cur

Axiom
annotated source: transmedullary Y neuron
annotated property: IAO_0000028
annotated target: TmY
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary Y neuron
annotated property: definition
annotated target: An intrinsic columnar neuron of the optic lobe whose cell body lies in the distal cortex of the medulla and that arborizes in the medulla and branches in the second optic chiasm with one branch innervating the lobula and the other the lobula plate.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: transmedullary Y neuron
annotated property: hasExactSynonym
annotated target: TmY
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary Y neuron TmY3
type: Class
subclass of: transmedullary Y neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary Y neuron TmY3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M10
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 4
IAO_0000028: TmY3
definition: Transmedullary Y neuron that terminates with bleb-type arborizations in lobula layers 4 and lobula plate layer 4. It displays fine arborizations in medulla layers M1, M2, M4, M5, M6, M8, and M10, and has bleb-type arborizations in medulla layers M5 and M10. It is cholinergic (Davis et al., 2020).
database_cross_reference: FlyBrain_NDB:10171
database_cross_reference: VFB:FBbt_00003820
has exact synonym: TmY3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003820
in subset: cur
comment: Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: transmedullary Y neuron TmY3
annotated property: IAO_0000028
annotated target: TmY3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary Y neuron TmY3
annotated property: definition
annotated target: Transmedullary Y neuron that terminates with bleb-type arborizations in lobula layers 4 and lobula plate layer 4. It displays fine arborizations in medulla layers M1, M2, M4, M5, M6, M8, and M10, and has bleb-type arborizations in medulla layers M5 and M10. It is cholinergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0244935

Axiom
annotated source: transmedullary Y neuron TmY3
annotated property: hasExactSynonym
annotated target: TmY3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary Y neuron TmY5a
type: Class
subclass of: transmedullary Y neuron
subclass of: narrow field transmedullary neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary Y neuron TmY5a
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula plate layer 1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula plate layer 3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M8
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 6
IAO_0000028: TmY5a
definition: Transmedullary Y narrow field neuron that terminates with both fine and bleb-type arborizations in lobula layers 4, 5 and 6, and in lobula plate layer 3, but only has fine arborizations in lobula plate layer 1. It displays both fine and bleb-type arborizations in medulla layers M6 and M8, and has fine arborizations in medulla layers M2, M3, M4, M5 and M9 (Morante and Desplan, 2008; Fischbach and Dittrich (1989). It is glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBrain_NDB:10174
database_cross_reference: VFB:FBbt_00003823
has exact synonym: TmY5a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003823
in subset: cur
comment: The identification of axons was done using a UAS-tau (P{UAS-tau-lacZ.O} - FBtp0010033) reporter (Morante and Desplan, 2008). The morphology of terminals was judged from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB.

Axiom
annotated source: transmedullary Y neuron TmY5a
annotated property: IAO_0000028
annotated target: TmY5a
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary Y neuron TmY5a
annotated property: definition
annotated target: Transmedullary Y narrow field neuron that terminates with both fine and bleb-type arborizations in lobula layers 4, 5 and 6, and in lobula plate layer 3, but only has fine arborizations in lobula plate layer 1. It displays both fine and bleb-type arborizations in medulla layers M6 and M8, and has fine arborizations in medulla layers M2, M3, M4, M5 and M9 (Morante and Desplan, 2008; Fischbach and Dittrich (1989). It is glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0244935

Axiom
annotated source: transmedullary Y neuron TmY5a
annotated property: hasExactSynonym
annotated target: TmY5a
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

proximal medullary amacrine neuron
type: Class
subclass of: optic lobe amacrine neuron
subclass of: medulla intrinsic neuron
IAO_0000028: Pm
definition: An amacrine neuron that is intrinsic to the medulla and that branches and arborizes in the proximal medulla. Generally, the soma is located in the cortex adjacent to the medulla and that projects through the proximal surface of the medulla, to form wide (sometimes very wide) terminal arborizations mainly or completely restricted to a single layer of the medulla.
database_cross_reference: VFB:FBbt_00003832
has exact synonym: Pm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003832
in subset: cur

Axiom
annotated source: proximal medullary amacrine neuron
annotated property: IAO_0000028
annotated target: Pm
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: proximal medullary amacrine neuron
annotated property: definition
annotated target: An amacrine neuron that is intrinsic to the medulla and that branches and arborizes in the proximal medulla. Generally, the soma is located in the cortex adjacent to the medulla and that projects through the proximal surface of the medulla, to form wide (sometimes very wide) terminal arborizations mainly or completely restricted to a single layer of the medulla.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: proximal medullary amacrine neuron
annotated property: hasExactSynonym
annotated target: Pm
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

medulla tangential neuron
type: Class
subclass of: optic lobe tangential neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla
IAO_0000028: Mt
definition: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more medulla layers.
database_cross_reference: VFB:FBbt_00003836
has exact synonym: Mt
has exact synonym: medullary tangential neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003836
in subset: cur

Axiom
annotated source: medulla tangential neuron
annotated property: IAO_0000028
annotated target: Mt
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla tangential neuron
annotated property: definition
annotated target: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more medulla layers.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: medulla tangential neuron
annotated property: hasExactSynonym
annotated target: Mt
database_cross_reference: FlyBase:FBrf0049410
has synonym type: VFB SYMBOL

lobula
type: Class
subclass of: anterior ectoderm derivative
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: lobula complex
subclass of: Restriction
  on property: develops from
  some values from: lobula anlage
definition: Anterior domain of the adult lobula complex. It can be divided into six layers and houses many columnar neurons.
database_cross_reference: VFB:FBbt_00003852
has exact synonym: LO
has exact synonym: Lob
has OBO namespace: fly_anatomy.ontology
has related synonym: Lo
id: FBbt:00003852
in subset: BrainName
in subset: cur

Axiom
annotated source: lobula
annotated property: definition
annotated target: Anterior domain of the adult lobula complex. It can be divided into six layers and houses many columnar neurons.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0231227

Axiom
annotated source: lobula
annotated property: hasExactSynonym
annotated target: LO
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: lobula
annotated property: hasExactSynonym
annotated target: Lob
database_cross_reference: FlyBase:FBrf0212704

lobula layer 1
type: Class
subclass of: lobula layer
definition: Layer of the lobula that abuts the second optic chiasm. It is defined by the bushy arborizations of the T5 neurons, and by the terminal arborizations of transmedullary neuron Tm1 and Tm9.
has alternative id: FBbt:00040012
database_cross_reference: VFB:FBbt_00003853
has exact synonym: T5 layer
has exact synonym: lobula layer Lo1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003853
in subset: cur

Axiom
annotated source: lobula layer 1
annotated property: definition
annotated target: Layer of the lobula that abuts the second optic chiasm. It is defined by the bushy arborizations of the T5 neurons, and by the terminal arborizations of transmedullary neuron Tm1 and Tm9.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula layer 1
annotated property: hasExactSynonym
annotated target: T5 layer
database_cross_reference: FlyBase:FBrf0049410

lobula layer 2
type: Class
subclass of: lobula layer
definition: Layer of the lobula that is second-most from the second optic chiasm. It is defined by the arborizations of lobula tangential neuron LT5.
has alternative id: FBbt:00040013
database_cross_reference: VFB:FBbt_00003854
has exact synonym: lobula layer Lo2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003854
in subset: cur

Axiom
annotated source: lobula layer 2
annotated property: definition
annotated target: Layer of the lobula that is second-most from the second optic chiasm. It is defined by the arborizations of lobula tangential neuron LT5.
database_cross_reference: FlyBase:FBrf0049410

lobula layer 3
type: Class
subclass of: lobula layer
definition: Layer of the lobula that is third-most from the second optic chiasm. It contains the arborizations of lobula tangential neuron LT6.
has alternative id: FBbt:00040014
database_cross_reference: VFB:FBbt_00003855
has exact synonym: lobula layer Lo3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003855
in subset: cur

Axiom
annotated source: lobula layer 3
annotated property: definition
annotated target: Layer of the lobula that is third-most from the second optic chiasm. It contains the arborizations of lobula tangential neuron LT6.
database_cross_reference: FlyBase:FBrf0049410

lobula layer 4
type: Class
subclass of: lobula layer
definition: Layer of the lobula that is fourth-most from the second optic chiasm. It contains the terminals of the translobula plate Tlp 2, 3, 4 and 5 neurons.
has alternative id: FBbt:00040015
database_cross_reference: VFB:FBbt_00003856
has exact synonym: lobula layer Lo4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003856
in subset: cur
comment: Fischbach and Dittrich, (1989), comment that lobula layer 4 could potentially be further subdivided based on the stratified arborizations of the Tlp neurons.

Axiom
annotated source: lobula layer 4
annotated property: definition
annotated target: Layer of the lobula that is fourth-most from the second optic chiasm. It contains the terminals of the translobula plate Tlp 2, 3, 4 and 5 neurons.
database_cross_reference: FlyBase:FBrf0049410

lobula tangential neuron
type: Class
subclass of: optic lobe tangential neuron
subclass of: adult visual projection neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula
IAO_0000028: LT
definition: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more layers of the lobula.
database_cross_reference: VFB:FBbt_00003859
has exact synonym: LT
has exact synonym: Lt
has exact synonym: lobular tangential neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003859
in subset: cur

Axiom
annotated source: lobula tangential neuron
annotated property: IAO_0000028
annotated target: LT
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula tangential neuron
annotated property: definition
annotated target: Tangential neuron of the optic lobe that projects and arborizes along the plane of one or more layers of the lobula.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula tangential neuron
annotated property: hasExactSynonym
annotated target: LT
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula tangential neuron
annotated property: hasExactSynonym
annotated target: Lt
database_cross_reference: FlyBase:FBrf0049410

lobula columnar neuron
type: Class
subclass of: adult optic lobe columnar neuron
subclass of: adult visual projection neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula
IAO_0000028: LC
definition: An extrinsic columnar neuron that innervates the lobula.
database_cross_reference: VFB:FBbt_00003870
has exact synonym: LC
has exact synonym: LCN
has exact synonym: Lcn
has exact synonym: lobular columnar neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003870
in subset: cur

Axiom
annotated source: lobula columnar neuron
annotated property: IAO_0000028
annotated target: LC
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula columnar neuron
annotated property: definition
annotated target: An extrinsic columnar neuron that innervates the lobula.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula columnar neuron
annotated property: hasExactSynonym
annotated target: LC
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula columnar neuron
annotated property: hasExactSynonym
annotated target: LCN
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula columnar neuron
annotated property: hasExactSynonym
annotated target: Lcn
database_cross_reference: FlyBase:FBrf0049410

lobula columnar neuron LC4
type: Class
subclass of: lobula columnar neuron
subclass of: adult cholinergic neuron
subclass of: adult glutamatergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: adult lateral brain cell body rind
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: LC4 optic glomerulus
IAO_0000028: LC4
definition: Lobula columnar neuron whose cell body is in an extended region of the lateral cell body rind (Wu et al., 2016). It has its main dendritic arbors in lobula layers 2 and 4 (Wu et al., 2016; Tanaka and Clark, 2022). Its arbors span approximately 40 optic columns, overlapping with other LC4 cells (Wu et al., 2016). It projects to an optic glomerulus in the PVLP that is medial to the one from LC12 and ventral to LPLC2 and LPLC1 (Wu et al., 2016). There are an estimated 66 neurons of this type (Wu et al., 2016). It has been reported as being both glutamatergic (Raghu and Borst, 2011) and cholinergic (Davis et al., 2020).
database_cross_reference: FlyBrain_NDB:10001
database_cross_reference: VFB:FBbt_00003874
has exact synonym: ColA
has exact synonym: LC04
has exact synonym: LC4
has exact synonym: lobula columnar neuron Lcn4
has exact synonym: lobular columnar neuron Lcn4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003874
in subset: cur
comment: The glutamate neurotransmitter was assessed by labelling cells with a vGlut[CNSIII]-GAL4 driver (FBti0129148) (Raghu and Borst, 2011). The acetylcholine neurotransmitter was assessed by scRNAseq detection of choline acetyltransferase (FBgn0000303) and vesicular acetylcholine transporter (FBgn0270928) expression (Davis et al., 2020). Otsuna states that lcn4 innervates an optic glomerulus in the vlpr and vlpr maps to the VLP in Ito et al. (2014). Pre- versus postsynaptic innervation judged by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB and with a presynaptic marker (synaptotagmin-HA driver) (Wu et al., 2016).

Axiom
annotated source: lobula columnar neuron LC4
annotated property: IAO_0000028
annotated target: LC4
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula columnar neuron LC4
annotated property: definition
annotated target: Lobula columnar neuron whose cell body is in an extended region of the lateral cell body rind (Wu et al., 2016). It has its main dendritic arbors in lobula layers 2 and 4 (Wu et al., 2016; Tanaka and Clark, 2022). Its arbors span approximately 40 optic columns, overlapping with other LC4 cells (Wu et al., 2016). It projects to an optic glomerulus in the PVLP that is medial to the one from LC12 and ventral to LPLC2 and LPLC1 (Wu et al., 2016). There are an estimated 66 neurons of this type (Wu et al., 2016). It has been reported as being both glutamatergic (Raghu and Borst, 2011) and cholinergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0213690
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0253297

Axiom
annotated source: lobula columnar neuron LC4
annotated property: hasExactSynonym
annotated target: ColA
database_cross_reference: FlyBase:FBrf0218239

Axiom
annotated source: lobula columnar neuron LC4
annotated property: hasExactSynonym
annotated target: LC04
database_cross_reference: FlyBase:FBrf0233032

Axiom
annotated source: lobula columnar neuron LC4
annotated property: hasExactSynonym
annotated target: LC4
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula columnar neuron LC4
annotated property: hasExactSynonym
annotated target: lobula columnar neuron Lcn4
database_cross_reference: FlyBase:FBrf0049410

lobula columnar neuron LC6
type: Class
subclass of: lobula columnar neuron
subclass of: adult cholinergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: adult lateral brain cell body rind
subclass of: Restriction
  on property: fasciculates with
  some values from: adult anterior optic tract
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula layer 5B
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: LC6 optic glomerulus
IAO_0000028: LC6
definition: Extrinsic lobula columnar neuron whose cell body is in the dorsal lateral cell body rind (Wu et al., 2016). It has its main dendritic arbors in lobula layers 4 and 5B (Wu et al., 2016), with most synapses concentrated in layer 5B (Tanaka and Clark, 2022). There is also some evidence of presynaptic sites in layers 4 and 5B (Wu et al., 2016). Its arbors span approximately 30 optic columns, overlapping with other LC6 cells (Wu et al., 2016). It fasciculates in the anterior optic tract, fasciculating with LC9 (Otsuna and Ito, 2006), and innervates an optic glomerulus in the dorsolateral PVLP, ventral to the one from LC16 (Wu et al., 2016; Morimoto et al., 2020). There are around 60 of these cells per hemisphere and they are cholinergic (Morimoto et al., 2020).
has broad synonym: S4
database_cross_reference: FlyBrain_NDB:10003
database_cross_reference: VFB:FBbt_00003876
has exact synonym: LC06
has exact synonym: LC6
has exact synonym: lobula columnar neuron Lcn6
has exact synonym: lobular columnar neuron Lcn6
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003876
in subset: cur

Axiom
annotated source: lobula columnar neuron LC6
annotated property: IAO_0000028
annotated target: LC6
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula columnar neuron LC6
annotated property: definition
annotated target: Extrinsic lobula columnar neuron whose cell body is in the dorsal lateral cell body rind (Wu et al., 2016). It has its main dendritic arbors in lobula layers 4 and 5B (Wu et al., 2016), with most synapses concentrated in layer 5B (Tanaka and Clark, 2022). There is also some evidence of presynaptic sites in layers 4 and 5B (Wu et al., 2016). Its arbors span approximately 30 optic columns, overlapping with other LC6 cells (Wu et al., 2016). It fasciculates in the anterior optic tract, fasciculating with LC9 (Otsuna and Ito, 2006), and innervates an optic glomerulus in the dorsolateral PVLP, ventral to the one from LC16 (Wu et al., 2016; Morimoto et al., 2020). There are around 60 of these cells per hemisphere and they are cholinergic (Morimoto et al., 2020).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0247630
database_cross_reference: FlyBase:FBrf0253297

Axiom
annotated source: lobula columnar neuron LC6
annotated property: hasBroadSynonym
annotated target: S4
database_cross_reference: FlyBase:FBrf0039022

Axiom
annotated source: lobula columnar neuron LC6
annotated property: hasExactSynonym
annotated target: LC06
database_cross_reference: FlyBase:FBrf0233032

Axiom
annotated source: lobula columnar neuron LC6
annotated property: hasExactSynonym
annotated target: LC6
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula columnar neuron LC6
annotated property: hasExactSynonym
annotated target: lobula columnar neuron Lcn6
database_cross_reference: FlyBase:FBrf0049410

lobula complex columnar neuron
type: Class
subclass of: adult optic lobe columnar neuron
subclass of: adult visual projection neuron
subclass of: Restriction
  on property: overlaps
  some values from: second optic chiasma
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula plate
definition: Columnar visual projection neuron that receives input in both the lobula and the lobula plate.
database_cross_reference: VFB:FBbt_00003879
has exact synonym: Lccn
has exact synonym: lobular complex columnar neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003879
in subset: cur

Axiom
annotated source: lobula complex columnar neuron
annotated property: definition
annotated target: Columnar visual projection neuron that receives input in both the lobula and the lobula plate.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0254308

Axiom
annotated source: lobula complex columnar neuron
annotated property: hasExactSynonym
annotated target: Lccn
database_cross_reference: FlyBase:FBrf0049410

lobula plate-lobula columnar neuron LPLC
type: Class
subclass of: lobula complex columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: adult lateral brain cell body rind
IAO_0000028: LPLC
definition: Lobula complex columnar neuron with its soma in the lateral brain cell body rind (Shinomiya et al., 2022). It has a dendritic branch with more proximal arbors in the lobula more distal arbors in the lobula plate (Fischbach and Dittrich, 1989; Strausfeld and Gilbert, 1992; Shinomiya et al., 2019; Shinomiya et al., 2022). It has an axonal branch that projects to the central brain (Fischbach and Dittrich, 1989; Strausfeld and Gilbert, 1992; Shinomiya et al., 2019; Shinomiya et al., 2022).
database_cross_reference: FlyBrain_NDB:10065
database_cross_reference: VFB:FBbt_00003880
has exact synonym: LPLC
has exact synonym: Lccn1
has exact synonym: lobula complex columnar neuron Lccn1
has exact synonym: lobula plate-lobula neuron LPL
has exact synonym: lobular complex columnar neuron Lccn1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003880
in subset: cur
comment: These neurons were first described in Drosophila by Fischbach and Dittrich (1989), who named them lobula complex columnar neurons type 1 (Lccn1). Similar neurons were later found in other diptera (Strausfeld and Gilbert, 1992) and named lobula plate-lobula neurons (LPL); that later terminology is now predominant in the literature.

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC
annotated property: definition
annotated target: Lobula complex columnar neuron with its soma in the lateral brain cell body rind (Shinomiya et al., 2022). It has a dendritic branch with more proximal arbors in the lobula more distal arbors in the lobula plate (Fischbach and Dittrich, 1989; Strausfeld and Gilbert, 1992; Shinomiya et al., 2019; Shinomiya et al., 2022). It has an axonal branch that projects to the central brain (Fischbach and Dittrich, 1989; Strausfeld and Gilbert, 1992; Shinomiya et al., 2019; Shinomiya et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0240360
database_cross_reference: FlyBase:FBrf0243899
database_cross_reference: FlyBase:FBrf0254308

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC
annotated property: hasExactSynonym
annotated target: LPLC
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC
annotated property: hasExactSynonym
annotated target: Lccn1
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBrain_NDB:10065

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC
annotated property: hasExactSynonym
annotated target: lobula complex columnar neuron Lccn1
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC
annotated property: hasExactSynonym
annotated target: lobula plate-lobula neuron LPL
database_cross_reference: FlyBase:FBrf0240360

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC
annotated property: hasExactSynonym
annotated target: lobular complex columnar neuron Lccn1
database_cross_reference: FlyBase:FBrf0049410

lobula-lobula plate columnar neuron LLPC
type: Class
subclass of: adult optic lobe neuron
subclass of: lobula complex columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult lobula plate
IAO_0000028: LLPC
definition: Lobula complex columnar neuron with its soma in the cell body rind of the lobula plate (Shinomiya et al., 2022). It has a dendritic branch with more proximal arbors in the lobula plate more distal arbors in the lobula (Fischbach and Dittrich, 1989; Strausfeld and Gilbert, 1992; Shinomiya et al., 2019; Shinomiya et al., 2022). It has an axonal branch that projects along a path posterior to the lobula plate to the central brain (Fischbach and Dittrich, 1989; Strausfeld and Gilbert, 1992; Shinomiya et al., 2019; Shinomiya et al., 2022).
database_cross_reference: FlyBrain_NDB:10035
database_cross_reference: FlyBrain_NDB:10066
database_cross_reference: VFB:FBbt_00003881
has exact synonym: LLPC
has exact synonym: Lccn2
has exact synonym: lobula complex columnar neuron Lccn2
has exact synonym: lobula-lobula plate neuron LLP
has exact synonym: lobular complex columnar neuron Lccn2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003881
in subset: cur
comment: These neurons were first described in Drosophila by Fischbach and Dittrich (1989), who named them lobula complex columnar neurons type 2 (Lccn2). Similar neurons were later found in other diptera (Strausfeld and Gilbert, 1992) and named lobula-lobula plate neurons (LLP); that later terminology is now predominant in the literature.

Axiom
annotated source: lobula-lobula plate columnar neuron LLPC
annotated property: definition
annotated target: Lobula complex columnar neuron with its soma in the cell body rind of the lobula plate (Shinomiya et al., 2022). It has a dendritic branch with more proximal arbors in the lobula plate more distal arbors in the lobula (Fischbach and Dittrich, 1989; Strausfeld and Gilbert, 1992; Shinomiya et al., 2019; Shinomiya et al., 2022). It has an axonal branch that projects along a path posterior to the lobula plate to the central brain (Fischbach and Dittrich, 1989; Strausfeld and Gilbert, 1992; Shinomiya et al., 2019; Shinomiya et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0240360
database_cross_reference: FlyBase:FBrf0243899
database_cross_reference: FlyBase:FBrf0254308

Axiom
annotated source: lobula-lobula plate columnar neuron LLPC
annotated property: hasExactSynonym
annotated target: LLPC
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula-lobula plate columnar neuron LLPC
annotated property: hasExactSynonym
annotated target: Lccn2
database_cross_reference: FlyBrain_NDB:10035

Axiom
annotated source: lobula-lobula plate columnar neuron LLPC
annotated property: hasExactSynonym
annotated target: lobula complex columnar neuron Lccn2
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula-lobula plate columnar neuron LLPC
annotated property: hasExactSynonym
annotated target: lobula-lobula plate neuron LLP
database_cross_reference: FlyBase:FBrf0240360

Axiom
annotated source: lobula-lobula plate columnar neuron LLPC
annotated property: hasExactSynonym
annotated target: lobular complex columnar neuron Lccn2
database_cross_reference: FlyBase:FBrf0049410

lobula intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: lobula
subclass of: adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: synapses restricted to region
  some values from: lobula
IAO_0000028: Li
definition: Neuron that only innervates the lobula.
database_cross_reference: VFB:FBbt_00003882
has exact synonym: Li
has exact synonym: lobular intrinsic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003882
in subset: cur

Axiom
annotated source: lobula intrinsic neuron
annotated property: IAO_0000028
annotated target: Li
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula intrinsic neuron
annotated property: definition
annotated target: Neuron that only innervates the lobula.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula intrinsic neuron
annotated property: hasExactSynonym
annotated target: Li
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

lobula plate
type: Class
subclass of: anterior ectoderm derivative
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: lobula complex
subclass of: Restriction
  on property: develops from
  some values from: lobula plate anlage
definition: Posterior domain of the adult lobula complex. It is divided into 4 layers and houses many large tangential neurons.
has alternative id: FBbt:00001947
database_cross_reference: VFB:FBbt_00003885
has exact synonym: LOP
has exact synonym: LoP
has exact synonym: lobula plate neuropil
has OBO namespace: fly_anatomy.ontology
has related synonym: Lop
id: FBbt:00003885
in subset: BrainName
in subset: cur

Axiom
annotated source: lobula plate
annotated property: definition
annotated target: Posterior domain of the adult lobula complex. It is divided into 4 layers and houses many large tangential neurons.
database_cross_reference: FlyBase:FBrf0231227
database_cross_reference: VFB_vol:00003885

Axiom
annotated source: lobula plate
annotated property: hasExactSynonym
annotated target: LOP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: lobula plate
annotated property: hasExactSynonym
annotated target: LoP
database_cross_reference: FlyBase:FBrf0212704

lobula plate layer 1
type: Class
subclass of: lobula plate layer
definition: Layer of the lobula plate that abuts the second optic chiasm (Fischbach and Dittrich, 1989). The dendritic arbors of the horizontal system neurons are found exclusively in this layer, alongside terminals of the T4a and T5a neurons (Fischbach and Dittrich, 1989). Neurons in this layer are sensitive to diagonal front-to-back motion, i.e. front top to back bottom or front bottom to back top (Henning et al., 2022).
has alternative id: FBbt:00040018
database_cross_reference: VFB:FBbt_00003886
has exact synonym: HS layer
has exact synonym: front-to-back layer
has exact synonym: layer Lop1
has exact synonym: lobula plate layer A
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003886
in subset: cur

Axiom
annotated source: lobula plate layer 1
annotated property: definition
annotated target: Layer of the lobula plate that abuts the second optic chiasm (Fischbach and Dittrich, 1989). The dendritic arbors of the horizontal system neurons are found exclusively in this layer, alongside terminals of the T4a and T5a neurons (Fischbach and Dittrich, 1989). Neurons in this layer are sensitive to diagonal front-to-back motion, i.e. front top to back bottom or front bottom to back top (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0041368
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: lobula plate layer 1
annotated property: hasExactSynonym
annotated target: front-to-back layer
database_cross_reference: FlyBase:FBrf0051327

Axiom
annotated source: lobula plate layer 1
annotated property: hasExactSynonym
annotated target: layer Lop1
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula plate layer 1
annotated property: hasExactSynonym
annotated target: lobula plate layer A
database_cross_reference: FlyBase:FBrf0252436

lobula plate layer 2
type: Class
subclass of: lobula plate layer
definition: Layer of the lobula plate that is second-closest to the second optic chiasm (Fischbach and Dittrich, 1989). Terminals of T4b and T5b are found in this layer (Fischbach and Dittrich, 1989). Neurons in this layer are sensitive to diagonal back-to-front motion, i.e. back top to front bottom or back bottom to front top (Henning et al., 2022).
has alternative id: FBbt:00040019
database_cross_reference: VFB:FBbt_00003887
has exact synonym: back-to-front-layer
has exact synonym: layer Lop2
has exact synonym: lobula plate layer B
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003887
in subset: cur

Axiom
annotated source: lobula plate layer 2
annotated property: definition
annotated target: Layer of the lobula plate that is second-closest to the second optic chiasm (Fischbach and Dittrich, 1989). Terminals of T4b and T5b are found in this layer (Fischbach and Dittrich, 1989). Neurons in this layer are sensitive to diagonal back-to-front motion, i.e. back top to front bottom or back bottom to front top (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0041368
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: lobula plate layer 2
annotated property: hasExactSynonym
annotated target: back-to-front-layer
database_cross_reference: FlyBase:FBrf0051327

Axiom
annotated source: lobula plate layer 2
annotated property: hasExactSynonym
annotated target: layer Lop2
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula plate layer 2
annotated property: hasExactSynonym
annotated target: lobula plate layer B
database_cross_reference: FlyBase:FBrf0252436

lobula plate layer 3
type: Class
subclass of: lobula plate layer
definition: Layer of the lobula plate that is third-closest to the second optic chiasm (Fischbach and Dittrich, 1989). The T4c and T5c neurons arborize in this layer (Fischbach and Dittrich, 1989). Neurons in this layer are sensitive to upward motion (Henning et al., 2022).
has alternative id: FBbt:00040020
database_cross_reference: VFB:FBbt_00003888
has exact synonym: layer Lop3
has exact synonym: lobula plate layer C
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003888
in subset: cur

Axiom
annotated source: lobula plate layer 3
annotated property: definition
annotated target: Layer of the lobula plate that is third-closest to the second optic chiasm (Fischbach and Dittrich, 1989). The T4c and T5c neurons arborize in this layer (Fischbach and Dittrich, 1989). Neurons in this layer are sensitive to upward motion (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0041368
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0179400
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: lobula plate layer 3
annotated property: hasExactSynonym
annotated target: layer Lop3
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula plate layer 3
annotated property: hasExactSynonym
annotated target: lobula plate layer C
database_cross_reference: FlyBase:FBrf0252436

lobula plate layer 4
type: Class
subclass of: lobula plate layer
definition: Layer of the lobula plate that is the most distant from the second optic chiasm (Fischbach and Dittrich, 1989). Terminals of T4d and T5d, and most of the vertical system neurons are found in this layer (Fischbach and Dittrich, 1989; Rajashekhar and Shamprasad, 2004). Neurons in this layer are sensitive to downward motion (Henning et al., 2022).
has alternative id: FBbt:00040021
database_cross_reference: VFB:FBbt_00003889
has exact synonym: layer Lop4
has exact synonym: lobula plate layer D
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003889
in subset: cur

Axiom
annotated source: lobula plate layer 4
annotated property: definition
annotated target: Layer of the lobula plate that is the most distant from the second optic chiasm (Fischbach and Dittrich, 1989). Terminals of T4d and T5d, and most of the vertical system neurons are found in this layer (Fischbach and Dittrich, 1989; Rajashekhar and Shamprasad, 2004). Neurons in this layer are sensitive to downward motion (Henning et al., 2022).
database_cross_reference: FlyBase:FBrf0041368
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0179400
database_cross_reference: FlyBase:FBrf0252436

Axiom
annotated source: lobula plate layer 4
annotated property: hasExactSynonym
annotated target: layer Lop4
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: lobula plate layer 4
annotated property: hasExactSynonym
annotated target: lobula plate layer D
database_cross_reference: FlyBase:FBrf0252436

lobula plate intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: lobula plate
subclass of: adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0000634
subclass of: Restriction
  on property: synapses restricted to region
  some values from: lobula plate
IAO_0000028: Lpi
definition: Any interneuron that innervates only the lobula plate (Raghu and Borst, 2011).
database_cross_reference: VFB:FBbt_00003910
has exact synonym: Lpi
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003910

Axiom
annotated source: lobula plate intrinsic neuron
annotated property: IAO_0000028
annotated target: Lpi
database_cross_reference: FlyBase:FBrf0213690

Axiom
annotated source: lobula plate intrinsic neuron
annotated property: definition
annotated target: Any interneuron that innervates only the lobula plate (Raghu and Borst, 2011).
database_cross_reference: FlyBase:FBrf0213690
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: lobula plate intrinsic neuron
annotated property: hasExactSynonym
annotated target: Lpi
database_cross_reference: FlyBase:FBrf0213690
has synonym type: VFB SYMBOL

optic chiasma
type: Class
subclass of: chiasma
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
definition: The projection of axons between the lamina and medulla (first optic chiasma) or between the medulla and lobula (second optic chiasma). The linear order of axons along each horizontal row of retinotopic cartridges or columns is reversed by the chiasma.
database_cross_reference: VFB:FBbt_00003921
has exact synonym: OCH
has exact synonym: optic chiasm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003921
in subset: cur

Axiom
annotated source: optic chiasma
annotated property: definition
annotated target: The projection of axons between the lamina and medulla (first optic chiasma) or between the medulla and lobula (second optic chiasma). The linear order of axons along each horizontal row of retinotopic cartridges or columns is reversed by the chiasma.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: optic chiasma
annotated property: hasExactSynonym
annotated target: OCH
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

second optic chiasma
type: Class
subclass of: optic chiasma
subclass of: Restriction
  on property: innervates
  some values from: medulla
subclass of: Restriction
  on property: innervates
  some values from: lobula
subclass of: Restriction
  on property: innervates
  some values from: lobula plate
definition: Chiasma lying between the medulla and the lobula/lobula plate of the optic lobe (Ito et al., 2014). Between the medulla and the lobula, neuronal fibers reverse their order, inverting the anterior-posterior axis of the visual field (Ito et al., 2014; Shinomiya et al., 2019). Between the medulla and lobula plate and between the lobula and lobula plate, fibers run in parallel, conserving the axes of the visual field (Shinomiya et al., 2019). Neurons travelling between the medulla and lobula complex form around 25-30 fiber bundles of varying widths, and neurons travelling between the same two neuropil columns do not necessarily fasciculate with the same bundle (Shinomiya et al., 2019). Neurons travelling between the lobula and lobula plate form sheet-like structures, neurons from the medulla bundles also merge into these sheets (Shinomiya et al., 2019). Sheets and bundles are wrapped by glial processes (Shinomiya et al., 2019). Approximately 20,000 neurons pass through each second optic chiasma (Shinomiya et al., 2019).
database_cross_reference: VFB:FBbt_00003922
has exact synonym: OCH2
has exact synonym: inner optic chiasm
has exact synonym: second optic chiasm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003922
in subset: cur
comment: The lobula lies opposite to the lobula plate, with the columns representing the anterior visual field being furthest from the medulla. For that reason, there is no chiasms between the medulla and lobula plate (Ito et al., 2014).

Axiom
annotated source: second optic chiasma
annotated property: definition
annotated target: Chiasma lying between the medulla and the lobula/lobula plate of the optic lobe (Ito et al., 2014). Between the medulla and the lobula, neuronal fibers reverse their order, inverting the anterior-posterior axis of the visual field (Ito et al., 2014; Shinomiya et al., 2019). Between the medulla and lobula plate and between the lobula and lobula plate, fibers run in parallel, conserving the axes of the visual field (Shinomiya et al., 2019). Neurons travelling between the medulla and lobula complex form around 25-30 fiber bundles of varying widths, and neurons travelling between the same two neuropil columns do not necessarily fasciculate with the same bundle (Shinomiya et al., 2019). Neurons travelling between the lobula and lobula plate form sheet-like structures, neurons from the medulla bundles also merge into these sheets (Shinomiya et al., 2019). Sheets and bundles are wrapped by glial processes (Shinomiya et al., 2019). Approximately 20,000 neurons pass through each second optic chiasma (Shinomiya et al., 2019).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0243899

Axiom
annotated source: second optic chiasma
annotated property: hasExactSynonym
annotated target: OCH2
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

deutocerebrum
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: neuromere
subclass of: Restriction
  on property: part of
  some values from: antennal segment
subclass of: Restriction
  on property: part of
  some values from: supraesophageal ganglion
definition: Neuromere of the antennal segment, located between the protocerebrum and tritocerebrum, connected to antennal nerve trunk (Urbach and Technau, 2003; Ito et al., 2014).
database_cross_reference: VFB:FBbt_00003923
has exact synonym: deuterocerebral neuromere
has exact synonym: deuterocerebrum
has exact synonym: deutocerebral neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003923
in subset: cur

Axiom
annotated source: deutocerebrum
annotated property: definition
annotated target: Neuromere of the antennal segment, located between the protocerebrum and tritocerebrum, connected to antennal nerve trunk (Urbach and Technau, 2003; Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: deutocerebrum
annotated property: hasExactSynonym
annotated target: deuterocerebral neuromere
database_cross_reference: FlyBase:FBrf0092819

tritocerebrum
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: neuromere
subclass of: Restriction
  on property: part of
  some values from: intercalary segment
subclass of: Restriction
  on property: part of
  some values from: supraesophageal ganglion
definition: Neuromere of intercalary segment, located between the deutocerebrum and the gnathal ganglion (Urbach and Technau, 2003; Hartenstein et al., 2018).
database_cross_reference: VFB:FBbt_00003999
has exact synonym: tritocerebral neuromere
has OBO namespace: fly_anatomy.ontology
id: FBbt:00003999
in subset: cur

Axiom
annotated source: tritocerebrum
annotated property: definition
annotated target: Neuromere of intercalary segment, located between the deutocerebrum and the gnathal ganglion (Urbach and Technau, 2003; Hartenstein et al., 2018).
database_cross_reference: FlyBase:FBrf0074226
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: tritocerebrum
annotated property: hasExactSynonym
annotated target: tritocerebral neuromere
database_cross_reference: FlyBase:FBrf0092819

adult subesophageal sensory interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: adult sensory region of subesophageal zone
subclass of: adult interneuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: adult sensory region of subesophageal zone
definition: Neuron of the adult central nervous system that has arborization in the sensory neuropil of the subesophageal zone.
database_cross_reference: VFB:FBbt_00004037
has narrow synonym: adult labial interneuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004037
in subset: cur

Axiom
annotated source: adult subesophageal sensory interneuron
annotated property: definition
annotated target: Neuron of the adult central nervous system that has arborization in the sensory neuropil of the subesophageal zone.
database_cross_reference: FlyBase:FBrf0042883

Axiom
annotated source: adult subesophageal sensory interneuron
annotated property: hasNarrowSynonym
annotated target: adult labial interneuron
database_cross_reference: FlyBase:FBrf0042883

adult sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Any sense organ of the adult.
database_cross_reference: VFB:FBbt_00004113
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004113
in subset: cur

Axiom
annotated source: adult sense organ
annotated property: definition
annotated target: Any sense organ of the adult.
database_cross_reference: FlyBase:FBrf0007734
database_cross_reference: FlyBase:FBrf0031004

head sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: head
subclass of: sensillum
subclass of: Restriction
  on property: part of
  some values from: head
definition: Any sensillum (FBbt:00007152) that is part of some head (FBbt:00000004).
database_cross_reference: UBERON:0000963
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004114
in subset: cur

Axiom
annotated source: head sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some head (FBbt:00000004).
database_cross_reference: FBC:Autogenerated

retina
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: eye
subclass of: Restriction
  on property: part of
  some values from: adult peripheral nervous system
definition: The array of photoreceptors and the cells that support them in a compound eye.
database_cross_reference: UBERON:0005388
database_cross_reference: VFB:FBbt_00004200
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004200
in subset: FB gloss
in subset: cur
comment: This is a very loosely used term. Definition based on consensus usage in literature.

Axiom
annotated source: retina
annotated property: definition
annotated target: The array of photoreceptors and the cells that support them in a compound eye.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral ectoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: ectoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: ventral ectoderm
definition: Anlage that develops into the ventral ectoderm. It is found in the lateroventral trunk region of the embryo at the cellular blastoderm stage, prior to gastrulation (Stathopoulos and Newcomb, 2020).
has exact synonym: presumptive neuroectoderm
has exact synonym: ventral/neuroectoderm anlage
has OBO namespace: fly_anatomy.ontology
has related synonym: Asn/A VenEc
id: FBbt:00004204
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral ectoderm anlage
annotated property: definition
annotated target: Anlage that develops into the ventral ectoderm. It is found in the lateroventral trunk region of the embryo at the cellular blastoderm stage, prior to gastrulation (Stathopoulos and Newcomb, 2020).
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: ventral ectoderm anlage
annotated property: hasExactSynonym
annotated target: presumptive neuroectoderm
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: ventral ectoderm anlage
annotated property: hasExactSynonym
annotated target: ventral/neuroectoderm anlage
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: ventral ectoderm anlage
annotated property: hasRelatedSynonym
annotated target: Asn/A VenEc
database_cross_reference: https://orcid.org/0000-0002-7073-9172

developing embryonic structure
type: Class
equivalent class: Class
  intersection of: developing material anatomical entity
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: developing material anatomical entity
subclass of: Restriction
  on property: part of
  some values from: embryo
definition: Any developing material anatomical entity of the embryo.
database_cross_reference: UBERON:0002050
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004208
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: developing embryonic structure
annotated property: definition
annotated target: Any developing material anatomical entity of the embryo.
database_cross_reference: FBC:Autogenerated

photoreceptor neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0016056
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050962
subclass of: sensory neuron
subclass of: visual system neuron
subclass of: Restriction
  on property: capable of
  some values from: GO_0016056
subclass of: Restriction
  on property: capable of
  some values from: GO_0050962
definition: Sensory neuron that reacts to the presence of light, due to the presence of rhodopsin.
database_cross_reference: CL:0000210
database_cross_reference: VFB:FBbt_00004211
has exact synonym: photoreceptor cell
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell
id: FBbt:00004211
in subset: cur

Axiom
annotated source: photoreceptor neuron
annotated property: definition
annotated target: Sensory neuron that reacts to the presence of light, due to the presence of rhodopsin.
database_cross_reference: FlyBase:FBrf0239342

photoreceptor cell R1
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: photoreceptor R1 precursor cell
IAO_0000028: R1
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the right angle vertex of the longer of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003710
database_cross_reference: CL:0000687
database_cross_reference: VFB:FBbt_00004213
has exact synonym: R1
has exact synonym: lamina receptor cell R1
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R1
id: FBbt:00004213
in subset: cur
comment: The name photoreceptor cell R1 is occasionally, mistakenly assumed to refer to any Rh1 (ninaE) expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R1 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (40/-), L2 (46/1), L3 (11/-), L4 (-/2), Lai (36/-), Lawf (1/1), epithelial glia (15/-), surface glia (1/-) and marginal glia (1/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R1
annotated property: IAO_0000028
annotated target: R1
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R1
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the right angle vertex of the longer of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R1
annotated property: hasExactSynonym
annotated target: R1
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R2
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: photoreceptor R2 precursor cell
IAO_0000028: R2
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located in the middle of the longer of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003711
database_cross_reference: CL:0000690
database_cross_reference: VFB:FBbt_00004215
has exact synonym: R2
has exact synonym: lamina receptor cell R2
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R2
id: FBbt:00004215
in subset: cur
comment: The name photoreceptor cell R2 is occasionally, mistakenly assumed to refer to any Rh2 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R2 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (43/-), L2 (45/1), L3 (10/-), L4 (-/1), Lai (39/-), T1 (2/-), Lawf (-/3), epithelial glia (13/-) and surface glia (1/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R2
annotated property: IAO_0000028
annotated target: R2
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R2
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located in the middle of the longer of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R2
annotated property: hasExactSynonym
annotated target: R2
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R3
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: photoreceptor R3 precursor cell
IAO_0000028: R3
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the non-right angled vertex of the longer of two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003712
database_cross_reference: CL:0000694
database_cross_reference: VFB:FBbt_00004217
has exact synonym: R3
has exact synonym: lamina receptor cell R3
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R3
id: FBbt:00004217
in subset: cur
comment: The name photoreceptor cell R3 is occasionally, mistakenly assumed to refer to any Rh3 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R3 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (37/-), L2 (39/-), L3 (4/-), L4 (-/3), Lai (39/-), T1 (2/-), C3 (2/1), Lawf (-/1) and epithelial glia (7/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R3
annotated property: IAO_0000028
annotated target: R3
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R3
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the non-right angled vertex of the longer of two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R3
annotated property: hasExactSynonym
annotated target: R3
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R4
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: photoreceptor R4 precursor cell
IAO_0000028: R4
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located in the middle of the longer of the two non-parallel sides of trapezoid of rhabdomeres in each ommatidium, in between the rhabdomeres of R3 and R5. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003713
database_cross_reference: CL:0000697
database_cross_reference: VFB:FBbt_00004219
has exact synonym: R4
has exact synonym: lamina receptor cell R4
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R4
id: FBbt:00004219
in subset: cur
comment: The name photoreceptor cell R4 is occasionally, mistakenly assumed to refer to any Rh4 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R4 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (38/-), L2 (41/-), L3 (8/-), L4 (-/1), Lai (37/2), T1 (2/-) and epithelial glia (9/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R4
annotated property: IAO_0000028
annotated target: R4
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R4
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located in the middle of the longer of the two non-parallel sides of trapezoid of rhabdomeres in each ommatidium, in between the rhabdomeres of R3 and R5. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R4
annotated property: hasExactSynonym
annotated target: R4
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R5
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: photoreceptor R5 precursor cell
IAO_0000028: R5
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located at a non-right angle vertex of the shorter of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003714
database_cross_reference: CL:0000702
database_cross_reference: VFB:FBbt_00004221
has exact synonym: R5
has exact synonym: lamina receptor cell R5
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R5
id: FBbt:00004221
in subset: cur
comment: The name photoreceptor cell R5 is occasionally, mistakenly assumed to refer to any Rh5 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R5 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (38/-), L2 (39/-), L3 (6/-), L4 (-/3), Lai (35/2), C2 (1/-), epithelial glia (10/-) and marginal glia (1/-) (Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R5
annotated property: IAO_0000028
annotated target: R5
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R5
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located at a non-right angle vertex of the shorter of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R5
annotated property: hasExactSynonym
annotated target: R5
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R6
type: Class
subclass of: outer photoreceptor cell
subclass of: Restriction
  on property: develops from
  some values from: photoreceptor R6 precursor cell
IAO_0000028: R6
definition: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the right angle vertex of the shorter of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
has alternative id: FBbt:00003715
database_cross_reference: CL:0000705
database_cross_reference: VFB:FBbt_00004223
has exact synonym: R6
has exact synonym: lamina receptor cell R6
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R6
id: FBbt:00004223
in subset: cur
comment: The name photoreceptor cell R6 is occasionally, mistakenly assumed to refer to any Rh6 expressing photoreceptor cell. This is incorrect. This term only refers to a type of adult eye photoreceptor cell. The name is based simply on the position of the cell and its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready, 1993. Cell connectivity was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for R6 (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: L1 (45/-), L2 (47/-), L3 (12/-), L4 (-/3), Lai (40/-), Lawf (-/1), epithelial glia (11/-) and marginal glia (2/-)(Rivera-Alba et al., 2011).

Axiom
annotated source: photoreceptor cell R6
annotated property: IAO_0000028
annotated target: R6
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R6
annotated property: definition
annotated target: Outer photoreceptor cell of the adult eye whose rhabdomere is located at the right angle vertex of the shorter of the two parallel sides of the trapezoid of rhabdomeres in each ommatidium. It has a single axon that projects along a single lamina optic cartridge (Fischbach and Dittrich, 1989; Wolff and Ready, 1993).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

Axiom
annotated source: photoreceptor cell R6
annotated property: hasExactSynonym
annotated target: R6
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R7
type: Class
subclass of: inner photoreceptor cell
subclass of: Restriction
  on property: overlaps
  some values from: optic cartridge
subclass of: Restriction
  on property: overlaps
  some values from: first optic chiasma
subclass of: Restriction
  on property: develops from
  some values from: photoreceptor R7 precursor cell
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M6
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R8
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: photoreceptor cell R8
IAO_0000028: R7
definition: Inner photoreceptor cell of the ommatidium whose rhabdomere is located distally, directly above that of R8 (Wernet and Desplan, 2004). It has a single axon that extends through a single column of the lamina without making synapses (Fischbach and Dittrich, 1989). This axon crosses the first optic chiasm and extends through a single column of the medulla where it makes pre-synaptic contacts, mainly in medulla layers M1 and M5 (Takemura et al., 2008), before terminating in M6 (Gao et al., 2008; Sancer et al., 2019). It forms reciprocal inhibitory histaminergic synapses with the R8 photoreceptor of the same optic column (Schnaitmann et al., 2018), with a large proportion in the first optic chiasm (Kind et al., 2021).
has alternative id: FBbt:00003716
database_cross_reference: CL:0000707
database_cross_reference: FlyBrain_NDB:10112
database_cross_reference: VFB:FBbt_00004225
has exact synonym: R7
has exact synonym: lamina receptor cell R7
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R7
id: FBbt:00004225
in subset: cur
comment: This term refers to a type of adult eye photoreceptor cell, defined based on the position of its rhabdomere within each ommatidium - see figure 4 in Wolff and Ready (1993). It does not refer to Rh7-expressing photoreceptors.

Axiom
annotated source: photoreceptor cell R7
annotated property: IAO_0000028
annotated target: R7
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R7
annotated property: definition
annotated target: Inner photoreceptor cell of the ommatidium whose rhabdomere is located distally, directly above that of R8 (Wernet and Desplan, 2004). It has a single axon that extends through a single column of the lamina without making synapses (Fischbach and Dittrich, 1989). This axon crosses the first optic chiasm and extends through a single column of the medulla where it makes pre-synaptic contacts, mainly in medulla layers M1 and M5 (Takemura et al., 2008), before terminating in M6 (Gao et al., 2008; Sancer et al., 2019). It forms reciprocal inhibitory histaminergic synapses with the R8 photoreceptor of the same optic column (Schnaitmann et al., 2018), with a large proportion in the first optic chiasm (Kind et al., 2021).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0237706
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: photoreceptor cell R7
annotated property: hasExactSynonym
annotated target: R7
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

photoreceptor cell R8
type: Class
subclass of: inner photoreceptor cell
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: overlaps
  some values from: optic cartridge
subclass of: Restriction
  on property: overlaps
  some values from: first optic chiasma
subclass of: Restriction
  on property: develops from
  some values from: photoreceptor R8 precursor cell
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R7
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: photoreceptor cell R7
IAO_0000028: R8
definition: Inner photoreceptor cell of the ommatidium whose rhabdomere is located proximally, directly below that of R7 (Wernet and Desplan, 2004). It has a single axon that extends through a single column of the lamina without making synapses and crosses the first optic chiasm to reach the medulla (Fischbach and Dittrich, 1989). It forms reciprocal inhibitory histaminergic synapses with the R8 photoreceptor of the same optic column (Schnaitmann et al., 2018), with a large proportion in the first optic chiasm (Kind et al., 2021). It is also cholinergic (Davis et al., 2020).
has alternative id: FBbt:00003717
database_cross_reference: CL:0000709
database_cross_reference: FlyBrain_NDB:10113
database_cross_reference: FlyBrain_NDB:10114
database_cross_reference: VFB:FBbt_00004227
has exact synonym: R8
has exact synonym: lamina receptor cell R8
has OBO namespace: fly_anatomy.ontology
has related synonym: receptor cell R8
id: FBbt:00004227
in subset: cur
comment: Fischbach and Dittrich (1989) suggest there may be two (non-DRA) variants of R8, one terminating in each of M3 and M4; this has not been substantiated in subsequent papers.

Axiom
annotated source: photoreceptor cell R8
annotated property: IAO_0000028
annotated target: R8
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: photoreceptor cell R8
annotated property: definition
annotated target: Inner photoreceptor cell of the ommatidium whose rhabdomere is located proximally, directly below that of R7 (Wernet and Desplan, 2004). It has a single axon that extends through a single column of the lamina without making synapses and crosses the first optic chiasm to reach the medulla (Fischbach and Dittrich, 1989). It forms reciprocal inhibitory histaminergic synapses with the R8 photoreceptor of the same optic column (Schnaitmann et al., 2018), with a large proportion in the first optic chiasm (Kind et al., 2021). It is also cholinergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0237706
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: photoreceptor cell R8
annotated property: hasExactSynonym
annotated target: R8
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

late extended germ band embryo
type: Class
subclass of: extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: early extended germ band embryo
definition: A collective term for stages 11 and 12.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004450
in subset: cur

Axiom
annotated source: late extended germ band embryo
annotated property: definition
annotated target: A collective term for stages 11 and 12.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

eye
type: Class
subclass of: adult sense organ
subclass of: photoreceptor
subclass of: external compound sense organ
subclass of: anterior ectoderm derivative
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: adult head
subclass of: Restriction
  on property: develops from
  some values from: eye disc
subclass of: Restriction
  on property: capable of
  some values from: GO_0050908
definition: A bilaterally paired compound sense organ of the adult head that functions in visual perception.
database_cross_reference: UBERON:0000018
database_cross_reference: VFB:FBbt_00004508
database_cross_reference: https://www.ento.csiro.au/biology/drosophila/melanogaster.html
has OBO namespace: fly_anatomy.ontology
has related synonym: compound eye
id: FBbt:00004508
in subset: FB gloss
in subset: cur

Axiom
annotated source: eye
annotated property: definition
annotated target: A bilaterally paired compound sense organ of the adult head that functions in visual perception.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ommatidium
type: Class
subclass of: photoreceptor
subclass of: external sensillum
subclass of: adult head sensillum
subclass of: Restriction
  on property: part of
  some values from: retina
subclass of: Restriction
  on property: develops from
  some values from: ommatidial precursor cluster
subclass of: Restriction
  on property: capable of
  some values from: GO_0050908
definition: One of the facets of the compound eye. It is composed of eight light-sensing photoreceptor cells (photoreceptor cell R1-R8) and accessory cells. There are around 800 ommatidia in each compound eye.
database_cross_reference: UBERON:0000971
database_cross_reference: VFB:FBbt_00004510
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004510
in subset: FB gloss
in subset: cur

Axiom
annotated source: ommatidium
annotated property: definition
annotated target: One of the facets of the compound eye. It is composed of eight light-sensing photoreceptor cells (photoreceptor cell R1-R8) and accessory cells. There are around 800 ommatidia in each compound eye.
database_cross_reference: FlyBase:FBrf0166419
database_cross_reference: FlyBase:FBrf0180690

organ system
type: Class
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: organism
definition: A division of the whole organism into specialized systems.
database_cross_reference: UBERON:0000467
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004856
in subset: cur

Axiom
annotated source: organ system
annotated property: definition
annotated target: A division of the whole organism into specialized systems.
database_cross_reference: FBC:GG

integumentary system
type: Class
subclass of: organ system
definition: The organ system that forms the covering layer of the animal.
database_cross_reference: UBERON:0002416
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004969
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: integumentary system
annotated property: definition
annotated target: The organ system that forms the covering layer of the animal.
database_cross_reference: FBC:GG

cuticle
type: Class
subclass of: acellular anatomical structure
subclass of: Restriction
  on property: part of
  some values from: integumentary system
subclass of: Restriction
  on property: develops from
  some values from: epidermis
definition: The outer non-living layer of the integumentary system that is secreted by the underlying epidermis.
database_cross_reference: UBERON:0001001
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004970
in subset: FB gloss
in subset: cur

Axiom
annotated source: cuticle
annotated property: definition
annotated target: The outer non-living layer of the integumentary system that is secreted by the underlying epidermis.
database_cross_reference: FlyBase:FBrf0064790

trichome
type: Class
subclass of: cuticular specialization
definition: Non-innervated projection of the cuticle around an actin-rich cellular process of an underlying epidermal cell.
database_cross_reference: UBERON:6004979
has OBO namespace: fly_anatomy.ontology
has related synonym: cell hair
id: FBbt:00004979
in subset: cur

Axiom
annotated source: trichome
annotated property: definition
annotated target: Non-innervated projection of the cuticle around an actin-rich cellular process of an underlying epidermal cell.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval cuticle
type: Class
subclass of: cuticle
subclass of: Restriction
  on property: part of
  some values from: larval integumentary system
definition: Cuticle of the late embryo or larva.
database_cross_reference: UBERON:6004983
has exact synonym: larval cuticle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00004983
in subset: cur

Axiom
annotated source: embryonic/larval cuticle
annotated property: definition
annotated target: Cuticle of the late embryo or larva.
database_cross_reference: FlyBase:FBrf0234504

epidermis
type: Class
subclass of: cuboidal/columnar epithelium
subclass of: Restriction
  on property: part of
  some values from: integumentary system
definition: Tissue composed of epithelial cells. It secretes and underlies the cuticle.
database_cross_reference: UBERON:0007376
has OBO namespace: fly_anatomy.ontology
has related synonym: hypoderm
has related synonym: hypodermis
id: FBbt:00004993
in subset: FB gloss
in subset: cur

Axiom
annotated source: epidermis
annotated property: definition
annotated target: Tissue composed of epithelial cells. It secretes and underlies the cuticle.
database_cross_reference: FlyBase:FBrf0064790

digestive system
type: Class
subclass of: organ system
definition: Organ system comprising the alimentary canal and its associated organs, including the mouthparts, labellar and salivary glands and the Malpighian tubules (Miller, 1950).
database_cross_reference: UBERON:0001007
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005055
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: digestive system
annotated property: definition
annotated target: Organ system comprising the alimentary canal and its associated organs, including the mouthparts, labellar and salivary glands and the Malpighian tubules (Miller, 1950).
database_cross_reference: FlyBase:FBrf0007735

apodeme
type: Class
subclass of: integumentary specialization
definition: A cuticular ingrowth of the exoskeleton, sometimes only a peg, frequently ridge-like, and often serving as a muscle attachment site. Does not generally correspond to superficial invaginations.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005091
in subset: FB gloss
in subset: cur

Axiom
annotated source: apodeme
annotated property: definition
annotated target: A cuticular ingrowth of the exoskeleton, sometimes only a peg, frequently ridge-like, and often serving as a muscle attachment site. Does not generally correspond to superficial invaginations.
database_cross_reference: FlyBase:FBrf0111704
database_cross_reference: FlyBase:FBrf0166419
database_cross_reference: FlyBase:FBrf0230923

nervous system
type: Class
subclass of: organ system
definition: All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.
database_cross_reference: UBERON:0001016
database_cross_reference: VFB:FBbt_00005093
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005093
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: nervous system
annotated property: definition
annotated target: All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.
database_cross_reference: FlyBase:FBrf0166419

central nervous system
type: Class
subclass of: organ system subdivision
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: Collective name for all the nerve centers and their connective in the insect's body. In the context of Drosophila refers to the part of the nervous system consisting of the brain and ventral ganglia.
database_cross_reference: UBERON:0001017
database_cross_reference: VFB:FBbt_00005094
has OBO namespace: fly_anatomy.ontology
has related synonym: CNS
id: FBbt:00005094
in subset: FB gloss
in subset: cur

Axiom
annotated source: central nervous system
annotated property: definition
annotated target: Collective name for all the nerve centers and their connective in the insect's body. In the context of Drosophila refers to the part of the nervous system consisting of the brain and ventral ganglia.
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0166419

brain
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Anterodorsal portion of the central nervous system. The neuromeres considered to be part of the brain vary by stage. In the larva, the cerebral (supraesophageal) neuromeres, which form a bilateral pair of lobes, constitute the brain (Urbach and Technau, 2003; Li et al., 2014; Crews, 2019). During metamorphosis, the gnathal ganglion separates from the prothoracic neuromere and fuses with the supraesophageal ganglion, to become the ventral part of the adult brain (Ito et al., 2014; Hartenstein et al., 2018; Kendroud et al., 2018).
database_cross_reference: UBERON:0000955
database_cross_reference: VFB:FBbt_00005095
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005095
in subset: FB gloss
in subset: cur

Axiom
annotated source: brain
annotated property: definition
annotated target: Anterodorsal portion of the central nervous system. The neuromeres considered to be part of the brain vary by stage. In the larva, the cerebral (supraesophageal) neuromeres, which form a bilateral pair of lobes, constitute the brain (Urbach and Technau, 2003; Li et al., 2014; Crews, 2019). During metamorphosis, the gnathal ganglion separates from the prothoracic neuromere and fuses with the supraesophageal ganglion, to become the ventral part of the adult brain (Ito et al., 2014; Hartenstein et al., 2018; Kendroud et al., 2018).
database_cross_reference: FlyBase:FBrf0161020
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0225812
database_cross_reference: FlyBase:FBrf0237251
database_cross_reference: FlyBase:FBrf0237252
database_cross_reference: FlyBase:FBrf0244240

peripheral nervous system
type: Class
subclass of: organ system subdivision
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: The outer parts of the nervous system that perform sensory and motor functions.
database_cross_reference: UBERON:0000010
database_cross_reference: VFB:FBbt_00005098
has OBO namespace: fly_anatomy.ontology
has related synonym: PNS
id: FBbt:00005098
in subset: FB gloss
in subset: cur

Axiom
annotated source: peripheral nervous system
annotated property: definition
annotated target: The outer parts of the nervous system that perform sensory and motor functions.
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0064796

neuron projection bundle
type: Class
equivalent class: Class
  intersection of: CARO_0001001
  intersection of: Restriction
    on property: part of
    some values from: Drosophila melanogaster
subclass of: CARO_0001001
subclass of: multi-cell-component structure
subclass of: Restriction
  on property: part of
  some values from: nervous system
subclass of: Restriction
  on property: characteristic of
  some values from: fasciculated
definition: A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses.
database_cross_reference: CARO:0001001
database_cross_reference: UBERON:0000122
database_cross_reference: VFB:FBbt_00005099
has exact synonym: nerve fiber bundle
has OBO namespace: fly_anatomy.ontology
has related synonym: nerve fiber
id: FBbt:00005099
in subset: cur
in subset: larval OF

Axiom
annotated source: neuron projection bundle
annotated property: definition
annotated target: A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: neuron projection bundle
annotated property: hasExactSynonym
annotated target: nerve fiber bundle
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: neuron projection bundle
annotated property: hasRelatedSynonym
annotated target: nerve fiber
database_cross_reference: https://orcid.org/0000-0002-7073-9172

tract
type: Class
subclass of: neuron projection bundle
subclass of: Restriction
  on property: part of
  some values from: tract neuropil
definition: A neuron projection bundle linking two or more synaptic neuropil domains or subdomains within the CNS.
database_cross_reference: UBERON:0001018
database_cross_reference: VFB:FBbt_00005100
has exact synonym: CNS tract
has narrow synonym: axon tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005100
in subset: cur
in subset: larval OF

Axiom
annotated source: tract
annotated property: definition
annotated target: A neuron projection bundle linking two or more synaptic neuropil domains or subdomains within the CNS.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

nerve
type: Class
equivalent class: Class
  intersection of: neuron projection bundle
  intersection of: Restriction
    on property: part of
    some values from: peripheral nervous system
subclass of: neuron projection bundle
subclass of: Restriction
  on property: part of
  some values from: peripheral nervous system
definition: A bundle of axons connecting the peripheral nervous system to the central nervous system.
database_cross_reference: UBERON:0001021
database_cross_reference: VFB:FBbt_00005105
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005105
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: nerve
annotated property: definition
annotated target: A bundle of axons connecting the peripheral nervous system to the central nervous system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

neuron
type: Class
equivalent class: Class
  intersection of: CL_0000540
  intersection of: Restriction
    on property: part of
    some values from: Drosophila melanogaster
subclass of: CL_0000540
subclass of: somatic cell
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: Electrically active cell of the nervous system which has an axon and/or dendrite and which is synapsed with other cells and/or has other cells synapsed to it.
database_cross_reference: CL:0000540
database_cross_reference: VFB:FBbt_00005106
has OBO namespace: fly_anatomy.ontology
has related synonym: nerve cell
id: FBbt:00005106
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
in subset: larval OF
in subset: scrnaseq slim

Axiom
annotated source: neuron
annotated property: definition
annotated target: Electrically active cell of the nervous system which has an axon and/or dendrite and which is synapsed with other cells and/or has other cells synapsed to it.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

sensory neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: CL_0000101
subclass of: sensory system neuron
definition: Any neuron (FBbt:00005106) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
database_cross_reference: CL:0000101
database_cross_reference: VFB:FBbt_00005124
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005124
in subset: cur
in subset: larval OF
in subset: scrnaseq slim

Axiom
annotated source: sensory neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
database_cross_reference: FBC:Autogenerated

interneuron
type: Class
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: A neuron that is entirely confined to the central nervous system and is neither a sensory neuron nor a motor neuron.
has alternative id: FBbt:00005126
database_cross_reference: CL:0000099
database_cross_reference: VFB:FBbt_00005125
has exact synonym: central neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005125
in subset: FB gloss
in subset: cur
in subset: larval OF
in subset: scrnaseq slim
comment: alt_id of FBbt:00005126 moved over following obsoletion of 'intrinsic neuron', unclear what this term was or whether 'interneuron' is a suitable replacement.

Axiom
annotated source: interneuron
annotated property: definition
annotated target: A neuron that is entirely confined to the central nervous system and is neither a sensory neuron nor a motor neuron.
database_cross_reference: FlyBase:FBrf0216671
database_cross_reference: FlyBase:FBrf0247998

Axiom
annotated source: interneuron
annotated property: hasExactSynonym
annotated target: central neuron
database_cross_reference: FlyBase:FBrf0247998

optic lobe amacrine neuron
type: Class
subclass of: adult optic lobe intrinsic neuron
definition: Optic lobe intrinsic neuron without defined axons or dendrites, having processes with mixed pre- and post-synapses in approximately the same ratio throughout the cell (Matsliah et al., 2024). Some amacrine cells, such as CT1, have multiple compartmentalized, modular arborizations (Meier and Borst, 2019).
has broad synonym: amacrine cell
database_cross_reference: VFB:FBbt_00005127
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005127
in subset: cur

Axiom
annotated source: optic lobe amacrine neuron
annotated property: definition
annotated target: Optic lobe intrinsic neuron without defined axons or dendrites, having processes with mixed pre- and post-synapses in approximately the same ratio throughout the cell (Matsliah et al., 2024). Some amacrine cells, such as CT1, have multiple compartmentalized, modular arborizations (Meier and Borst, 2019).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0242197
database_cross_reference: FlyBase:FBrf0260545

adult optic lobe columnar neuron
type: Class
subclass of: adult interneuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: adult optic lobe
definition: Interneuron of the optic lobe whose primary projection extends along the long axis of a single optic column to which it, but not necessarily its collaterals, is restricted.
database_cross_reference: VFB:FBbt_00005129
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005129
in subset: cur
comment: This definition follows Fischbach and Dittrich (1989) in classifying based on the primary projection. A neuron with broad and extensive collaterals with terminals in adjacent columns is still classified as a columnar neuron under this definition. Other treatments have classified such neurons as tangential.

Axiom
annotated source: adult optic lobe columnar neuron
annotated property: definition
annotated target: Interneuron of the optic lobe whose primary projection extends along the long axis of a single optic column to which it, but not necessarily its collaterals, is restricted.
database_cross_reference: FlyBase:FBrf0049410

dopaminergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0061527
subclass of: CL_0000700
subclass of: aminergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature dopaminergic neuron
definition: Any neuron (FBbt:00005106) that is capable of some dopamine secretion, neurotransmission (GO:0061527).
database_cross_reference: CL:0000700
database_cross_reference: VFB:FBbt_00005131
has exact synonym: DA neuron
has exact synonym: dopamine neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005131
in subset: cur

Axiom
annotated source: dopaminergic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some dopamine secretion, neurotransmission (GO:0061527).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: dopaminergic neuron
annotated property: hasExactSynonym
annotated target: DA neuron
database_cross_reference: FlyBase:FBrf0208427

ganglion
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: nervous system
definition: Any of a number of aggregations of neurons, glial cells and their processes, and surrounded by a glial cell and connective tissue sheath (plural: ganglia).
database_cross_reference: VFB:FBbt_00005137
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005137
in subset: FB gloss
in subset: cur
in subset: larval OF

neuropil
type: Class
subclass of: multi-cell-component structure
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Multi-cell component structure of the central nervous system consisting largely of neuron projections (tracts and synaptic neuropil domains) and associated glial cells. This corresponds to the part of the CNS that is enclosed by the cortex.
has alternative id: FBbt:00007351
database_cross_reference: UBERON:0002606
database_cross_reference: VFB:FBbt_00005139
has OBO namespace: fly_anatomy.ontology
has related synonym: neuropil
id: FBbt:00005139

Axiom
annotated source: neuropil
annotated property: definition
annotated target: Multi-cell component structure of the central nervous system consisting largely of neuron projections (tracts and synaptic neuropil domains) and associated glial cells. This corresponds to the part of the CNS that is enclosed by the cortex.
database_cross_reference: FlyBase:FBrf0224194

neuromere
type: Class
subclass of: segmental subdivision of organ system
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: A segmental subdivision of the nervous system.
database_cross_reference: VFB:FBbt_00005140
has OBO namespace: fly_anatomy.ontology
has related synonym: ganglion
id: FBbt:00005140
in subset: FB gloss
in subset: cur

Axiom
annotated source: neuromere
annotated property: definition
annotated target: A segmental subdivision of the nervous system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

glial cell
type: Class
subclass of: somatic cell
subclass of: Restriction
  on property: part of
  some values from: nervous system
subclass of: Restriction
  on property: develops from
  some values from: glioblast
definition: A supporting cell of the nervous system.
database_cross_reference: CL:0000125
database_cross_reference: VFB:FBbt_00005144
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005144
in subset: FB gloss
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: glial cell
annotated property: definition
annotated target: A supporting cell of the nervous system.
database_cross_reference: FBC:GG

glioblast
type: Class
subclass of: neuroblast
definition: Progenitor cell that gives rise only to glial cells and not neurons (Hartenstein, 2011).
database_cross_reference: CL:0000340
database_cross_reference: VFB:FBbt_00005145
has exact synonym: glial precursor cell
has OBO namespace: fly_anatomy.ontology
has related synonym: GP
id: FBbt:00005145
in subset: cur

Axiom
annotated source: glioblast
annotated property: definition
annotated target: Progenitor cell that gives rise only to glial cells and not neurons (Hartenstein, 2011).
database_cross_reference: FlyBase:FBrf0064795
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: glioblast
annotated property: hasRelatedSynonym
annotated target: GP
database_cross_reference: FlyBase:FBrf0055900

neuroblast
type: Class
subclass of: somatic stem cell
IAO_0000028: NB
definition: Precursor of the central nervous system that derives from the neurogenic region of the ectoderm or the mesectoderm (Doe, 1992; Schmid et al., 1999; Crews, 2019). It produces neurons and/or glia (Doe, 1992; Beckervordersandforth et al., 2008). Neuroblasts may also divide during adult life to regenerate the adult brain (Fernandez-Hernandez et al., 2013).
database_cross_reference: CL:0000338
database_cross_reference: VFB:FBbt_00005146
has exact synonym: NB
has exact synonym: neural stem cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005146
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
comment: Adult neurogenesis demonstrated in the adult optic lobe in response to injury (Fernandez-Hernandez et al., 2013).

Axiom
annotated source: neuroblast
annotated property: definition
annotated target: Precursor of the central nervous system that derives from the neurogenic region of the ectoderm or the mesectoderm (Doe, 1992; Schmid et al., 1999; Crews, 2019). It produces neurons and/or glia (Doe, 1992; Beckervordersandforth et al., 2008). Neuroblasts may also divide during adult life to regenerate the adult brain (Fernandez-Hernandez et al., 2013).
database_cross_reference: FlyBase:FBrf0055900
database_cross_reference: FlyBase:FBrf0112030
database_cross_reference: FlyBase:FBrf0205499
database_cross_reference: FlyBase:FBrf0222020
database_cross_reference: FlyBase:FBrf0244240

Axiom
annotated source: neuroblast
annotated property: hasExactSynonym
annotated target: NB
has synonym type: VFB SYMBOL

Axiom
annotated source: neuroblast
annotated property: hasExactSynonym
annotated target: neural stem cell
database_cross_reference: FlyBase:FBrf0211926

sense organ
type: Class
equivalent class: Class
  intersection of: multicellular structure
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: BFO_0000040
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: sensory system
subclass of: Restriction
  on property: capable of
  some values from: GO_0050906
definition: Multicellular anatomical structure with largely bona fide boundary that transduces some sensory stimulus to the nervous system.
database_cross_reference: UBERON:0000020
database_cross_reference: VFB:FBbt_00005155
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005155
in subset: FB gloss
in subset: cur
in subset: hidden assertion
in subset: larval OF

Axiom
annotated source: sense organ
annotated property: definition
annotated target: Multicellular anatomical structure with largely bona fide boundary that transduces some sensory stimulus to the nervous system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

photoreceptor
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050962
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: visual system
subclass of: Restriction
  on property: capable of
  some values from: GO_0050962
definition: A light sensitive sense organ.
database_cross_reference: UBERON:0000970
database_cross_reference: VFB:FBbt_00005162
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005162
in subset: FB gloss
in subset: cur

Axiom
annotated source: photoreceptor
annotated property: definition
annotated target: A light sensitive sense organ.
database_cross_reference: FBC:GG

sensory organ cell
type: Class
equivalent class: Class
  intersection of: somatic cell
  intersection of: Restriction
    on property: overlaps
    some values from: sense organ
subclass of: somatic cell
subclass of: Restriction
  on property: overlaps
  some values from: sense organ
definition: Any somatic cell (FBbt:00100318) that overlaps some sense organ (FBbt:00005155).
has OBO namespace: fly_anatomy.ontology
has related synonym: SOC
id: FBbt:00005163
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: sensory organ cell
annotated property: definition
annotated target: Any somatic cell (FBbt:00100318) that overlaps some sense organ (FBbt:00005155).
database_cross_reference: FBC:Autogenerated

external sensory organ precursor cell
type: Class
subclass of: peripheral sensory precursor cell
definition: Precursor cell that gives rise to at least one cell of an external sensory organ.
has broad synonym: es cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005164
in subset: cur

Axiom
annotated source: external sensory organ precursor cell
annotated property: definition
annotated target: Precursor cell that gives rise to at least one cell of an external sensory organ.
database_cross_reference: FlyBase:FBrf0111371

Axiom
annotated source: external sensory organ precursor cell
annotated property: hasBroadSynonym
annotated target: es cell
database_cross_reference: FlyBase:FBrf0045361

external sensory organ precursor cell I
type: Class
subclass of: sensory mother cell
subclass of: external sensory organ precursor cell
definition: First-order precursor cell: mother of all the clonally related cells of an external sensory organ.
has broad synonym: SOP
has exact synonym: external sensory organ sensory mother cell
has OBO namespace: fly_anatomy.ontology
has related synonym: SOPI
has related synonym: founder cell
id: FBbt:00005165
in subset: cur

Axiom
annotated source: external sensory organ precursor cell I
annotated property: definition
annotated target: First-order precursor cell: mother of all the clonally related cells of an external sensory organ.
database_cross_reference: FlyBase:FBrf0049554
database_cross_reference: FlyBase:FBrf0111371
database_cross_reference: FlyBase:FBrf0158845

Axiom
annotated source: external sensory organ precursor cell I
annotated property: hasBroadSynonym
annotated target: SOP
database_cross_reference: FlyBase:FBrf0241429

external sensory organ
type: Class
subclass of: sense organ
definition: Sensory organ that has external structures that detect mechanical or chemical stimuli.
database_cross_reference: UBERON:6005168
database_cross_reference: VFB:FBbt_00005168
has exact synonym: eo
has exact synonym: es
has OBO namespace: fly_anatomy.ontology
has related synonym: sensillum
id: FBbt:00005168
in subset: cur
in subset: larval OF

Axiom
annotated source: external sensory organ
annotated property: definition
annotated target: Sensory organ that has external structures that detect mechanical or chemical stimuli.
database_cross_reference: FlyBase:FBrf0064796

Axiom
annotated source: external sensory organ
annotated property: hasExactSynonym
annotated target: es
database_cross_reference: FlyBase:FBrf0064796

pre-blastoderm embryo
type: Class
subclass of: embryo
definition: Embryo prior to the formation of the syncitial blastoderm, shortly after nuclear cycle 9 (Foe and Alberts, 1983; Jaeger et al., 2012). This period lasts from fertilization to the end of embryonic stage 3 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00005290
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005290

Axiom
annotated source: pre-blastoderm embryo
annotated property: definition
annotated target: Embryo prior to the formation of the syncitial blastoderm, shortly after nuclear cycle 9 (Foe and Alberts, 1983; Jaeger et al., 2012). This period lasts from fertilization to the end of embryonic stage 3 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0039741
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0220623

stage 1 embryo
type: Class
subclass of: cleavage stage embryo
subclass of: pre-blastoderm embryo
definition: Nuclear divisions 1 and 2. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005291
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 1 embryo
annotated property: definition
annotated target: Nuclear divisions 1 and 2. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

stage 2 embryo
type: Class
subclass of: cleavage stage embryo
subclass of: pre-blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 1 embryo
definition: Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005293
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 2 embryo
annotated property: definition
annotated target: Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).
database_cross_reference: FlyBase:FBrf0089570

stage 3 embryo
type: Class
subclass of: cleavage stage embryo
subclass of: syncytial blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 2 embryo
definition: Nuclear division 9. The cleavage nuclei complete there migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005301
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 3 embryo
annotated property: definition
annotated target: Nuclear division 9. The cleavage nuclei complete there migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

blastoderm embryo
type: Class
subclass of: embryo
definition: Embryo during the blastoderm stage, where most nuclei are found at the cortex (periphery) of the embryo (Foe and Alberts, 1983; Jaeger et al., 2012). The blastoderm stage begins shortly after completion of the ninth cleavage division and lasts until the onset of gastrulation, including cleavage cycles 10-14A (Foe and Alberts, 1983; Jaeger et al., 2012). This corresponds to embryonic stages 4 (syncitial blastoderm stage) and 5 (cellular blastoderm stage) (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00005304
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005304

Axiom
annotated source: blastoderm embryo
annotated property: definition
annotated target: Embryo during the blastoderm stage, where most nuclei are found at the cortex (periphery) of the embryo (Foe and Alberts, 1983; Jaeger et al., 2012). The blastoderm stage begins shortly after completion of the ninth cleavage division and lasts until the onset of gastrulation, including cleavage cycles 10-14A (Foe and Alberts, 1983; Jaeger et al., 2012). This corresponds to embryonic stages 4 (syncitial blastoderm stage) and 5 (cellular blastoderm stage) (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0039741
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0220623

syncytial blastoderm embryo
type: Class
subclass of: blastoderm embryo
definition: A blastoderm embryo prior to cellularization (corresponds to embryonic stages 3 and 4).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005305
in subset: cur
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: syncytial blastoderm embryo
annotated property: definition
annotated target: A blastoderm embryo prior to cellularization (corresponds to embryonic stages 3 and 4).
database_cross_reference: FBC:GG
database_cross_reference: https://orcid.org/0000-0002-7073-9172

stage 4 embryo
type: Class
subclass of: cleavage stage embryo
subclass of: syncytial blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 3 embryo
definition: Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005306
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 4 embryo
annotated property: definition
annotated target: Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

stage 5 embryo
type: Class
subclass of: blastoderm embryo
subclass of: Restriction
  on property: develops from
  some values from: stage 4 embryo
definition: Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees C: approximately 40 minutes (130-170 minutes after egg laying).
has OBO namespace: fly_anatomy.ontology
has related synonym: cellular blastoderm embryo
id: FBbt:00005311
in subset: deprecated
comment: DEPRECATION WARNING.

Axiom
annotated source: stage 5 embryo
annotated property: definition
annotated target: Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees C: approximately 40 minutes (130-170 minutes after egg laying).
database_cross_reference: FBC:MA
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: https://orcid.org/0000-0002-7073-9172

gastrula embryo
type: Class
subclass of: embryo
subclass of: Restriction
  on property: develops from
  some values from: blastoderm embryo
definition: Embryo that is in the process of gastrulation (encompassing embryonic stages 6-8), during which complex morphogenetic movements result in the formation of the three germ layers; ectoderm, mesoderm and endoderm (Hartenstein, 1993).
database_cross_reference: FBdv:00005317
database_cross_reference: UBERON:0004734
has exact synonym: gastrulation stage embryo
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005317

Axiom
annotated source: gastrula embryo
annotated property: definition
annotated target: Embryo that is in the process of gastrulation (encompassing embryonic stages 6-8), during which complex morphogenetic movements result in the formation of the three germ layers; ectoderm, mesoderm and endoderm (Hartenstein, 1993).
database_cross_reference: FlyBase:FBrf0064803

extended germ band embryo
type: Class
subclass of: embryo
subclass of: Restriction
  on property: develops from
  some values from: gastrula embryo
definition: Embryo during stages 9-12.
database_cross_reference: FBdv:00005321
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005321

Axiom
annotated source: extended germ band embryo
annotated property: definition
annotated target: Embryo during stages 9-12.
database_cross_reference: FlyBase:FBrf0229323
database_cross_reference: https://orcid.org/0000-0002-7073-9172

dorsal closure embryo
type: Class
subclass of: embryo
subclass of: Restriction
  on property: develops from
  some values from: late extended germ band embryo
definition: Embryo during the dorsal closure stage, which corresponds to stages 13-15 (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). Dorsal closure occurs by extension of the dorsal epidermal primordium on either side, leading to fusion at the dorsal midline (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FBdv:00005331
has OBO namespace: fly_anatomy.ontology
has related synonym: contracted germ band embryo
has related synonym: head involution embryo
id: FBbt:00005331

Axiom
annotated source: dorsal closure embryo
annotated property: definition
annotated target: Embryo during the dorsal closure stage, which corresponds to stages 13-15 (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). Dorsal closure occurs by extension of the dorsal epidermal primordium on either side, leading to fusion at the dorsal midline (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570

late embryo
type: Class
subclass of: embryo
subclass of: Restriction
  on property: develops from
  some values from: dorsal closure embryo
definition: Embryo during stages 16 and 17.
database_cross_reference: FBdv:00005333
database_cross_reference: UBERON:0000323
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005333

Axiom
annotated source: late embryo
annotated property: definition
annotated target: Embryo during stages 16 and 17.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

hindgut
type: Class
subclass of: multi-tissue structure
subclass of: gut section
subclass of: Restriction
  on property: expresses
  some values from: FBgn0011723
definition: A posterior part of the alimentary canal derived from the ectoderm. It extends anteriorly from close to the point of attachment of the Malpighian tubules to the anus. It is lined on its luminal side by an impermeable cuticle (Skaer, 1993).
database_cross_reference: UBERON:0001046
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005384
in subset: FB gloss
in subset: cur
comment: Adult and larval hindguts express the transcription factor brachyenteron (Sawyer et al., 2017).

Axiom
annotated source: hindgut
annotated property: definition
annotated target: A posterior part of the alimentary canal derived from the ectoderm. It extends anteriorly from close to the point of attachment of the Malpighian tubules to the anus. It is lined on its luminal side by an impermeable cuticle (Skaer, 1993).
database_cross_reference: FBC:GG
database_cross_reference: FlyBase:FBrf0064792

glomerulus
type: Class
subclass of: synaptic neuropil subdomain
definition: Roundish subunit structure of synaptic neuropil, often ensheathed by glial lamellae and reflecting the terminal arborization domain(s) of one or more neurons.
database_cross_reference: UBERON:0001047
database_cross_reference: VFB:FBbt_00005386
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005386
in subset: FB gloss
in subset: cur
in subset: larval OF

presumptive embryonic/larval integumentary system
type: Class
subclass of: presumptive embryonic/larval system
definition: The sum of all the structures in the embryo that will develop into the embryonic/larval integumentary system.
has OBO namespace: fly_anatomy.ontology
has related synonym: embryonic integumentary system
id: FBbt:00005392
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: presumptive embryonic/larval integumentary system
annotated property: definition
annotated target: The sum of all the structures in the embryo that will develop into the embryonic/larval integumentary system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: presumptive embryonic/larval integumentary system
annotated property: hasRelatedSynonym
annotated target: embryonic integumentary system
database_cross_reference: https://orcid.org/0000-0002-7073-9172

larval integumentary system
type: Class
equivalent class: Class
  intersection of: integumentary system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: integumentary system
subclass of: Restriction
  on property: part of
  some values from: larva
definition: Integumentary system of the late embryo or larva.
database_cross_reference: UBERON:6005393
has exact synonym: embryonic/larval integumentary system
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005393
in subset: cur

Axiom
annotated source: larval integumentary system
annotated property: definition
annotated target: Integumentary system of the late embryo or larva.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult integumentary system
type: Class
equivalent class: Class
  intersection of: integumentary system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: integumentary system
subclass of: Restriction
  on property: part of
  some values from: adult
definition: Integumentary system of the adult.
has alternative id: FBbt:00004474
database_cross_reference: UBERON:6005396
has exact synonym: adult integument
has OBO namespace: fly_anatomy.ontology
has related synonym: adult external
id: FBbt:00005396
in subset: cur

Axiom
annotated source: adult integumentary system
annotated property: definition
annotated target: Integumentary system of the adult.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic epidermis
type: Class
subclass of: epidermis
subclass of: Restriction
  on property: part of
  some values from: presumptive embryonic/larval integumentary system
definition: Epidermis of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005397
in subset: cur

Axiom
annotated source: embryonic epidermis
annotated property: definition
annotated target: Epidermis of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

anlage in statu nascendi
type: Class
subclass of: developing embryonic structure
definition: Domain that is in the process of forming an anlage and does not yet coincide 1:1 with a mature structure. These domains can be identified based on the expression of genes characteristic of the corresponding anlagen and are typically found in the early blastoderm.
has OBO namespace: fly_anatomy.ontology
has related synonym: A0
id: FBbt:00005413
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: anlage in statu nascendi
annotated property: definition
annotated target: Domain that is in the process of forming an anlage and does not yet coincide 1:1 with a mature structure. These domains can be identified based on the expression of genes characteristic of the corresponding anlagen and are typically found in the early blastoderm.
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0178740

visual anlage in statu nascendi
type: Class
subclass of: anlage in statu nascendi
subclass of: Restriction
  on property: part of
  some values from: stage 5 embryo
subclass of: Restriction
  on property: part of
  some values from: anterior ectoderm anlage
definition: Anlage in statu nascendi of the visual system in a stage 5 embryo that will give rise to the visual system anlage.
has exact synonym: Asn VisSys
has OBO namespace: fly_anatomy.ontology
has related synonym: A0Vis
id: FBbt:00005425
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: visual anlage in statu nascendi
annotated property: definition
annotated target: Anlage in statu nascendi of the visual system in a stage 5 embryo that will give rise to the visual system anlage.
database_cross_reference: FBC:VH

Axiom
annotated source: visual anlage in statu nascendi
annotated property: hasExactSynonym
annotated target: Asn VisSys
database_cross_reference: https://orcid.org/0000-0002-7073-9172

anlage
type: Class
subclass of: portion of tissue
subclass of: developing material anatomical entity
definition: Population of contiguous cells, typically arranged in one plane, that is morphologically indistinct from surrounding cells, but already corresponds to a later organ/tissue and can be identified based on gene expression or lineage tracing (Tomancak et al., 2002; Hartenstein, 2004).
database_cross_reference: UBERON:0007688
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005426
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: anlage
annotated property: definition
annotated target: Population of contiguous cells, typically arranged in one plane, that is morphologically indistinct from surrounding cells, but already corresponds to a later organ/tissue and can be identified based on gene expression or lineage tracing (Tomancak et al., 2002; Hartenstein, 2004).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0178740

ectoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: develops into
  some values from: ectoderm
definition: Cells of the early embryo that will become the ectoderm following gastrulation (Campos-Ortega and Hartenstein, 1997). It remains at the surface of the embryo as the endodermal and mesodermal anlagen invaginate (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: UBERON:6005427
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005427
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ectoderm anlage
annotated property: definition
annotated target: Cells of the early embryo that will become the ectoderm following gastrulation (Campos-Ortega and Hartenstein, 1997). It remains at the surface of the embryo as the endodermal and mesodermal anlagen invaginate (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0244630

visual anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: anterior ectoderm
subclass of: Restriction
  on property: part of
  some values from: gastrula embryo
subclass of: Restriction
  on property: develops from
  some values from: visual anlage in statu nascendi
subclass of: Restriction
  on property: develops into
  some values from: visual primordium
definition: Anlage of the visual system in the gastrula embryo that will give rise to the visual primordium.
has broad synonym: eye field
has exact synonym: A VisSys
has OBO namespace: fly_anatomy.ontology
has related synonym: AVis
id: FBbt:00005434
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: visual anlage
annotated property: definition
annotated target: Anlage of the visual system in the gastrula embryo that will give rise to the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0141490

Axiom
annotated source: visual anlage
annotated property: hasBroadSynonym
annotated target: eye field
database_cross_reference: FlyBase:FBrf0141490

Axiom
annotated source: visual anlage
annotated property: hasExactSynonym
annotated target: A VisSys
database_cross_reference: https://orcid.org/0000-0002-7073-9172

primordium
type: Class
subclass of: developing material anatomical entity
subclass of: Restriction
  on property: develops from
  some values from: anlage
definition: Precursor structure that can be recognized based on its distinct morphology and will give rise to one or more differentiated structures (Tomancak et al., 2002; Hartenstein, 2004). It develops from an anlage and may contain smaller anlage and primordia that will produce substructures (Tomancak et al., 2002).
database_cross_reference: UBERON:0001048
has OBO namespace: fly_anatomy.ontology
has related synonym: P
has related synonym: placode
id: FBbt:00005495
in subset: EmbDevSlim
in subset: FB gloss
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: primordium
annotated property: definition
annotated target: Precursor structure that can be recognized based on its distinct morphology and will give rise to one or more differentiated structures (Tomancak et al., 2002; Hartenstein, 2004). It develops from an anlage and may contain smaller anlage and primordia that will produce substructures (Tomancak et al., 2002).
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0155831
database_cross_reference: FlyBase:FBrf0178740

early embryonic primordium of adult eye
type: Class
subclass of: embryonic primordium of adult eye
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops into
  some values from: late embryonic primordium of adult eye
definition: Early primordium of the late extended germ band and dorsal closure embryo that will give rise to the adult eye. It develops from the visual primordium.
has exact synonym: adult eye primordium early
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005515
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: early embryonic primordium of adult eye
annotated property: definition
annotated target: Early primordium of the late extended germ band and dorsal closure embryo that will give rise to the adult eye. It develops from the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral epidermis primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: ventral ectoderm derivative
subclass of: Class
  intersection of: Restriction
    on property: develops into
    some values from: imaginal disc primordium
  intersection of: Restriction
    on property: develops into
    some values from: embryonic ventral epidermis
  intersection of: Restriction
    on property: develops into
    some values from: ventral trunk epidermis primordium
  intersection of: Restriction
    on property: develops into
    some values from: anal pad primordium
  intersection of: Restriction
    on property: develops into
    some values from: ventral apodeme anlage
  intersection of: Restriction
    on property: develops into
    some values from: denticle field anlage
subclass of: Restriction
  on property: part of
  some values from: early extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral neurectoderm
definition: A(n) primordium that develops into some denticle field anlage and some anal pad primordium and some embryonic ventral epidermis and some imaginal disc primordium and some ventral apodeme anlage and some ventral trunk epidermis primordium. It develops from some ventral neurectoderm.
database_cross_reference: UBERON:6005533
has OBO namespace: fly_anatomy.ontology
has related synonym: P2 iVenEp
has related synonym: venEpiP2
id: FBbt:00005533
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral epidermis primordium
annotated property: definition
annotated target: A(n) primordium that develops into some denticle field anlage and some anal pad primordium and some embryonic ventral epidermis and some imaginal disc primordium and some ventral apodeme anlage and some ventral trunk epidermis primordium. It develops from some ventral neurectoderm.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: ventral epidermis primordium
annotated property: hasRelatedSynonym
annotated target: P2 iVenEp
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral ectoderm
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: trunk ectoderm
subclass of: Restriction
  on property: develops from
  some values from: ventral ectoderm anlage
definition: Ventral region of the trunk ectoderm, which gives rise to the ventral epidermis and the central nervous system (Stathopoulos and Newcomb, 2020).
database_cross_reference: UBERON:6005558
has exact synonym: neuroectoderm
has exact synonym: neurogenic ectoderm
has OBO namespace: fly_anatomy.ontology
has related synonym: P2 VenEc
has related synonym: venEc
id: FBbt:00005558
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral ectoderm
annotated property: definition
annotated target: Ventral region of the trunk ectoderm, which gives rise to the ventral epidermis and the central nervous system (Stathopoulos and Newcomb, 2020).
database_cross_reference: FlyBase:FBrf0244630
database_cross_reference: FlyBase:FBrf0246683

Axiom
annotated source: ventral ectoderm
annotated property: hasExactSynonym
annotated target: neuroectoderm
database_cross_reference: FlyBase:FBrf0244630

Axiom
annotated source: ventral ectoderm
annotated property: hasExactSynonym
annotated target: neurogenic ectoderm
database_cross_reference: FlyBase:FBrf0246683

Axiom
annotated source: ventral ectoderm
annotated property: hasRelatedSynonym
annotated target: P2 VenEc
database_cross_reference: https://orcid.org/0000-0002-7073-9172

lamina anlage glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: lamina anlage
subclass of: CNS glial cell
subclass of: embryonic/larval lateral glial cell
subclass of: Restriction
  on property: part of
  some values from: lamina anlage
definition: Any glial cell (FBbt:00005144) that is part of some lamina anlage (FBbt:00001939).
database_cross_reference: VFB:FBbt_00005720
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005720
in subset: cur

Axiom
annotated source: lamina anlage glial cell
annotated property: definition
annotated target: Any glial cell (FBbt:00005144) that is part of some lamina anlage (FBbt:00001939).
database_cross_reference: FBC:Autogenerated

epithelial glial cell
type: Class
subclass of: neuropil glial cell
subclass of: Restriction
  on property: part of
  some values from: brain
definition: Cuboidal glial cell found in the visual system of larvae and adults, located more distal than the row of marginal glial cells. These glial cells contact marginal glia at their base (proximal) and satellite glia at their apex (distal), and constitute the only class of cells with nuclei in the neuropil proper, in the distal lamina.
database_cross_reference: VFB:FBbt_00005721
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005721
in subset: cur

Axiom
annotated source: epithelial glial cell
annotated property: definition
annotated target: Cuboidal glial cell found in the visual system of larvae and adults, located more distal than the row of marginal glial cells. These glial cells contact marginal glia at their base (proximal) and satellite glia at their apex (distal), and constitute the only class of cells with nuclei in the neuropil proper, in the distal lamina.
database_cross_reference: FlyBase:FBrf0055906
database_cross_reference: FlyBase:FBrf0134808
database_cross_reference: FlyBase:FBrf0214261

adult lamina marginal glial cell
type: Class
equivalent class: Class
  intersection of: ensheathing glial cell
  intersection of: Restriction
    on property: part of
    some values from: lamina
subclass of: adult optic lobe ensheathing glial cell
subclass of: adult lamina neuropil associated glial cell
subclass of: Restriction
  on property: part of
  some values from: optic cartridge
definition: Specialized ensheathing glial cell of the lamina (Edwards et al., 2012; Kremer et al., 2017). These cells form a contiguous layer at the proximal surface of the lamina and associate with multiple lamina columns (Edwards et al., 2012; Kremer et al., 2017). Their processes extend into the lamina, ensheathing proximal parts of the cartridges (Kremer et al., 2017). They also extend protrusions proximally into the outer chiasm (Kremer et al., 2017). It is between the marginal glial cells and epithelial glial cells that the R1-R6 growth cones terminate (Poeck et al., 2001; Winberg et al., 1992). There are around 100 of these cells per lamina (Kremer et al., 2017).
has alternative id: FBbt:00100515
database_cross_reference: VFB:FBbt_00005722
has exact synonym: L-EG
has exact synonym: adult lamina ensheathing glial cell
has OBO namespace: fly_anatomy.ontology
has related synonym: proximal glial cell
id: FBbt:00005722
in subset: cur

Axiom
annotated source: adult lamina marginal glial cell
annotated property: definition
annotated target: Specialized ensheathing glial cell of the lamina (Edwards et al., 2012; Kremer et al., 2017). These cells form a contiguous layer at the proximal surface of the lamina and associate with multiple lamina columns (Edwards et al., 2012; Kremer et al., 2017). Their processes extend into the lamina, ensheathing proximal parts of the cartridges (Kremer et al., 2017). They also extend protrusions proximally into the outer chiasm (Kremer et al., 2017). It is between the marginal glial cells and epithelial glial cells that the R1-R6 growth cones terminate (Poeck et al., 2001; Winberg et al., 1992). There are around 100 of these cells per lamina (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0055906
database_cross_reference: FlyBase:FBrf0134808
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0218414
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina marginal glial cell
annotated property: hasExactSynonym
annotated target: L-EG
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina marginal glial cell
annotated property: hasExactSynonym
annotated target: adult lamina ensheathing glial cell
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina marginal glial cell
annotated property: hasRelatedSynonym
annotated target: proximal glial cell
database_cross_reference: FlyBase:FBrf0134808

adult lamina satellite glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: cell body rind of adult lamina
subclass of: adult optic lobe cell body glial cell
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult lamina
subclass of: Restriction
  on property: develops from
  some values from: developing satellite glial cell
definition: Cell body glial cell of the lamina. Unlike in other cell body rind regions of the brain, the cell body glia of the lamina form two distinct layers and multiple neuronal cell bodies may be found in one glial pocket (Kremer et al., 2017).
has alternative id: FBbt:00100508
database_cross_reference: VFB:FBbt_00005723
has exact synonym: lamina cortex glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005723
in subset: cur

Axiom
annotated source: adult lamina satellite glial cell
annotated property: definition
annotated target: Cell body glial cell of the lamina. Unlike in other cell body rind regions of the brain, the cell body glia of the lamina form two distinct layers and multiple neuronal cell bodies may be found in one glial pocket (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0210316
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina satellite glial cell
annotated property: hasExactSynonym
annotated target: lamina cortex glial cell
database_cross_reference: FlyBase:FBrf0234767

adult medulla neuropil associated glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: medulla
subclass of: adult optic lobe glial cell
subclass of: Restriction
  on property: part of
  some values from: medulla
definition: Glial cell located in the medulla neuropil. There are at least three subtypes of reticular glia and at least two subtypes of ensheathing glia (Kremer et al., 2017).
database_cross_reference: VFB:FBbt_00005738
has OBO namespace: fly_anatomy.ontology
has related synonym: MNG
id: FBbt:00005738

Axiom
annotated source: adult medulla neuropil associated glial cell
annotated property: definition
annotated target: Glial cell located in the medulla neuropil. There are at least three subtypes of reticular glia and at least two subtypes of ensheathing glia (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0096428
database_cross_reference: FlyBase:FBrf0134808
database_cross_reference: FlyBase:FBrf0210316
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult medulla neuropil associated glial cell
annotated property: hasRelatedSynonym
annotated target: MNG
database_cross_reference: FlyBase:FBrf0096428

embryonic ventral epidermis
type: Class
subclass of: ventral ectoderm derivative
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: embryonic epidermis
subclass of: Restriction
  on property: develops from
  some values from: ventral epidermis primordium
definition: Epidermis of the ventral region of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005747
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic ventral epidermis
annotated property: definition
annotated target: Epidermis of the ventral region of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic anal pad
type: Class
subclass of: anal pad
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic ventral epidermis
subclass of: Restriction
  on property: develops from
  some values from: anal pad primordium
definition: Anal pad of the embryo.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005748
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic anal pad
annotated property: definition
annotated target: Anal pad of the embryo.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic ventral apodeme
type: Class
subclass of: apodeme
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic ventral epidermis
subclass of: Restriction
  on property: develops from
  some values from: ventral apodeme primordium
definition: Ventral halve of an embryonic apodeme. The discontinuity between dorsal and ventral halves is visible on a lateral view.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005749
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic ventral apodeme
annotated property: definition
annotated target: Ventral halve of an embryonic apodeme. The discontinuity between dorsal and ventral halves is visible on a lateral view.
database_cross_reference: FlyBase:FBrf0089570

anal pad
type: Class
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: hindgut
definition: Plate or plates that surrounds the anus.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005785
in subset: cur

Axiom
annotated source: anal pad
annotated property: definition
annotated target: Plate or plates that surrounds the anus.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

Bolwig organ
type: Class
subclass of: larval ocular segment sense organ
subclass of: photoreceptor
subclass of: internal sensillum
subclass of: embryonic/larval head sensillum
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: late embryo
subclass of: Restriction
  on property: develops from
  some values from: Bolwig organ primordium
subclass of: Restriction
  on property: capable of
  some values from: GO_0050908
definition: Visual organ of the larva that is anchored to the basal surface of the thin epithelium of the dorsal pouch, lateral to the musculature of the pharynx (Green et al., 1993; Hartenstein et al., 2019). It consists of a dense cluster of approximately 12 photoreceptor neurons and no support cells (Green et al., 1993; Hartenstein et al., 2019). It is connected to the brain via the Bolwig nerve (Green et al., 1993).
has alternative id: FBbt:00002643
has alternative id: FBbt:00005742
has alternative id: FBbt:00015250
database_cross_reference: UBERON:6005805
database_cross_reference: VFB:FBbt_00005805
has exact synonym: Bolwig's organ
has exact synonym: embryonic Bolwig's organ
has exact synonym: embryonic visual system
has exact synonym: larval Bolwig's organ
has exact synonym: larval eye
has exact synonym: stemmata organ
has OBO namespace: fly_anatomy.ontology
has related synonym: dorsocaudal pharyngeal sense organ
id: FBbt:00005805
in subset: FB gloss
in subset: cur
comment: Location in ocular segment on basis of FBrf0075072.

Axiom
annotated source: Bolwig organ
annotated property: definition
annotated target: Visual organ of the larva that is anchored to the basal surface of the thin epithelium of the dorsal pouch, lateral to the musculature of the pharynx (Green et al., 1993; Hartenstein et al., 2019). It consists of a dense cluster of approximately 12 photoreceptor neurons and no support cells (Green et al., 1993; Hartenstein et al., 2019). It is connected to the brain via the Bolwig nerve (Green et al., 1993).
database_cross_reference: FlyBase:FBrf0064481
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0243080

Axiom
annotated source: Bolwig organ
annotated property: hasExactSynonym
annotated target: larval eye
database_cross_reference: FlyBase:FBrf0213587

Axiom
annotated source: Bolwig organ
annotated property: hasExactSynonym
annotated target: stemmata organ
database_cross_reference: FlyBase:FBrf0047902

antennal sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: sense organ
subclass of: Restriction
  on property: part of
  some values from: antennal segment
definition: Any sense organ (FBbt:00005155) that is part of some antennal segment (FBbt:00000009).
has alternative id: FBbt:00004171
database_cross_reference: VFB:FBbt_00005806
has exact synonym: antennal sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005806
in subset: cur

Axiom
annotated source: antennal sense organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is part of some antennal segment (FBbt:00000009).
database_cross_reference: FBC:Autogenerated

first optic chiasma
type: Class
subclass of: optic chiasma
subclass of: Restriction
  on property: innervates
  some values from: lamina
subclass of: Restriction
  on property: innervates
  some values from: medulla
definition: Chiasma lying between the lamina and medulla of the optic lobe (Ito et al., 2014). Axons reverse the anterior-posterior order between the lamina and the medulla, with axons from the anterior lamina cartridges projecting to the posterior medulla columns (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00005810
has exact synonym: OCH1
has exact synonym: first optic chiasm
has exact synonym: outer optic chiasm
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005810
in subset: cur

Axiom
annotated source: first optic chiasma
annotated property: definition
annotated target: Chiasma lying between the lamina and medulla of the optic lobe (Ito et al., 2014). Axons reverse the anterior-posterior order between the lamina and the medulla, with axons from the anterior lamina cartridges projecting to the posterior medulla columns (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: first optic chiasma
annotated property: hasExactSynonym
annotated target: OCH1
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

chiasma
type: Class
subclass of: tract
definition: A tract of crossing fibers, that remaps or systematically permutates the linear order between two neuropils.
has alternative id: FBbt:00005102
database_cross_reference: VFB:FBbt_00005814
has exact synonym: chiasm
has exact synonym: decussation
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005814
in subset: cur

Axiom
annotated source: chiasma
annotated property: definition
annotated target: A tract of crossing fibers, that remaps or systematically permutates the linear order between two neuropils.
database_cross_reference: FlyBase:FBrf0224194

embryonic outer optic lobe primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic optic lobe primordium
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: larval outer optic anlage
definition: Primordium of the late extended germ band and closure embryo that gives rise to the larval outer optic anlage. It develops from the posterior lip of the visual primordium.
has exact synonym: P1 OOA
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005822
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic outer optic lobe primordium
annotated property: definition
annotated target: Primordium of the late extended germ band and closure embryo that gives rise to the larval outer optic anlage. It develops from the posterior lip of the visual primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: embryonic outer optic lobe primordium
annotated property: hasExactSynonym
annotated target: P1 OOA
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Bolwig organ primordium
type: Class
subclass of: primordium
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: Bolwig organ
definition: Primordium of the embryo that gives rise to the larval Bolwig organ. It develops from the most posterior region of the visual primordium, remaining attached to the surface as the rest of the optic placode becomes internalized during stages 12-13 (Green et al., 1993). It consists of approximately 12 cells, which begin to differentiate into photoreceptors during stage 13 (Green et al., 1993). During stages 15-16, the photoreceptors move out of the epidermis and come to lie attached to the outer lining of the dorsal pouch (Green et al., 1993).
database_cross_reference: UBERON:6005830
has exact synonym: Bolwig's organ primordium
has exact synonym: P1 BolOrg
has exact synonym: larval eye primordium
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005830
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: Bolwig organ primordium
annotated property: definition
annotated target: Primordium of the embryo that gives rise to the larval Bolwig organ. It develops from the most posterior region of the visual primordium, remaining attached to the surface as the rest of the optic placode becomes internalized during stages 12-13 (Green et al., 1993). It consists of approximately 12 cells, which begin to differentiate into photoreceptors during stage 13 (Green et al., 1993). During stages 15-16, the photoreceptors move out of the epidermis and come to lie attached to the outer lining of the dorsal pouch (Green et al., 1993).
database_cross_reference: FlyBase:FBrf0064481
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: FlyBase:FBrf0243080

Axiom
annotated source: Bolwig organ primordium
annotated property: hasExactSynonym
annotated target: P1 BolOrg
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: Bolwig organ primordium
annotated property: hasExactSynonym
annotated target: larval eye primordium
database_cross_reference: FlyBase:FBrf0141490

adult peripheral nervous system
type: Class
equivalent class: Class
  intersection of: peripheral nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: peripheral nervous system
subclass of: Restriction
  on property: part of
  some values from: adult nervous system
definition: Peripheral nervous system of the adult.
database_cross_reference: VFB:FBbt_00005892
has exact synonym: adult PNS
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005892
in subset: cur

Axiom
annotated source: adult peripheral nervous system
annotated property: definition
annotated target: Peripheral nervous system of the adult.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

larval peripheral nervous system
type: Class
equivalent class: Class
  intersection of: peripheral nervous system
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: peripheral nervous system
subclass of: Restriction
  on property: part of
  some values from: larval nervous system
definition: Peripheral nervous system of the embryo or larva.
database_cross_reference: VFB:FBbt_00005893
has exact synonym: embryonic/larval PNS
has exact synonym: embryonic/larval peripheral nervous system
has exact synonym: larval PNS
has OBO namespace: fly_anatomy.ontology
id: FBbt:00005893
in subset: cur
in subset: larval OF

Axiom
annotated source: larval peripheral nervous system
annotated property: definition
annotated target: Peripheral nervous system of the embryo or larva.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

outer photoreceptor cell
type: Class
subclass of: eye photoreceptor cell
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: optic cartridge
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: optic cartridge
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron L2
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina intrinsic neuron Lai
definition: An eye photoreceptor cell whose rhabdomere is part of the outer trapezoid of rhabdomeres of each ommatidium. There are six of these per ommatidium. Each has a single axon that projects along a single lamina optic cartridge within which it makes extensive synaptic connections before terminating in the proximal lamina. It is strongly presynaptic to lamina monopolar neurons L1 and L2 and the lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011).
database_cross_reference: FlyBrain_NDB:10111
database_cross_reference: VFB:FBbt_00006007
has exact synonym: photoreceptor cell R1-6
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006007
in subset: cur

Axiom
annotated source: outer photoreceptor cell
annotated property: definition
annotated target: An eye photoreceptor cell whose rhabdomere is part of the outer trapezoid of rhabdomeres of each ommatidium. There are six of these per ommatidium. Each has a single axon that projects along a single lamina optic cartridge within which it makes extensive synaptic connections before terminating in the proximal lamina. It is strongly presynaptic to lamina monopolar neurons L1 and L2 and the lamina intrinsic (amacrine) neuron (Rivera-Alba et al., 2011).
database_cross_reference: FlyBase:FBrf0054529
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0216925

inner photoreceptor cell
type: Class
subclass of: eye photoreceptor cell
definition: Eye photoreceptor cell whose rhabdomere is located in the center of each ommatidium.
database_cross_reference: VFB:FBbt_00006008
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006008
in subset: cur

Axiom
annotated source: inner photoreceptor cell
annotated property: definition
annotated target: Eye photoreceptor cell whose rhabdomere is located in the center of each ommatidium.
database_cross_reference: FlyBase:FBrf0064798

eye photoreceptor cell
type: Class
subclass of: CL_0000210
subclass of: sensory organ cell
subclass of: rhabdomeric photoreceptor cell
subclass of: adult histaminergic neuron
subclass of: adult sensory neuron
subclass of: adult PNS neuron
subclass of: Restriction
  on property: part of
  some values from: ommatidium
subclass of: Restriction
  on property: has soma location
  some values from: retina
subclass of: Restriction
  on property: develops from
  some values from: eye photoreceptor precursor cell
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: adult optic lobe
definition: Photoreceptor cell that forms the core of each ommatidium in the adult eye. Eight of these photoreceptors are arranged in each ommatidial core, bundled like the staves of a barrel. Each has a photosensitive rhabdomere that projects into the barrel cavity and adjacent supporting membrane, the stalk (Wolff and Ready, 1993). Each extends an axon into the optic lobe. Activation of the photoreceptor by light results in depolarization and in histamine release at the synapses of these axons (Sarthy, 1991).
has alternative id: FBbt:00003709
database_cross_reference: CL:2000019
database_cross_reference: VFB:FBbt_00006009
has exact synonym: lamina receptor cell
has exact synonym: retinula cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006009
in subset: cur
comment: Note - eyelet photoreceptors are NOT sub-types.

Axiom
annotated source: eye photoreceptor cell
annotated property: definition
annotated target: Photoreceptor cell that forms the core of each ommatidium in the adult eye. Eight of these photoreceptors are arranged in each ommatidial core, bundled like the staves of a barrel. Each has a photosensitive rhabdomere that projects into the barrel cavity and adjacent supporting membrane, the stalk (Wolff and Ready, 1993). Each extends an axon into the optic lobe. Activation of the photoreceptor by light results in depolarization and in histamine release at the synapses of these axons (Sarthy, 1991).
database_cross_reference: FlyBase:FBrf0054495
database_cross_reference: FlyBase:FBrf0064798

Axiom
annotated source: eye photoreceptor cell
annotated property: hasExactSynonym
annotated target: retinula cell
database_cross_reference: FlyBase:FBrf0012179

pharate adult
type: Class
subclass of: organism
subclass of: Restriction
  on property: develops from
  some values from: pupa
definition: The developing adult after pupal-adult apolysis, i.e. from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion.
database_cross_reference: UBERON:6006011
has OBO namespace: fly_anatomy.ontology
id: FBbt:00006011
in subset: FB gloss
in subset: cur

Axiom
annotated source: pharate adult
annotated property: definition
annotated target: The developing adult after pupal-adult apolysis, i.e. from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion.
database_cross_reference: FlyBase:FBrf0049147

anatomical structure
type: Class
subclass of: material anatomical entity
definition: Material anatomical entity that has inherent 3D shape, whose parts are all connected and that is generated by coordinated expression of the organism's own genome.
database_cross_reference: CARO:0000003
database_cross_reference: UBERON:0000061
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007001
in subset: cur
in subset: larval OF

Axiom
annotated source: anatomical structure
annotated property: definition
annotated target: Material anatomical entity that has inherent 3D shape, whose parts are all connected and that is generated by coordinated expression of the organism's own genome.
database_cross_reference: https://orcid.org/0000-0001-9114-8737
database_cross_reference: https://orcid.org/0000-0002-7073-9172

cell
type: Class
subclass of: anatomical structure
definition: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: CARO:0000013
database_cross_reference: CL:0000000
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007002
in subset: FB gloss
in subset: cur
in subset: larval OF

Axiom
annotated source: cell
annotated property: definition
annotated target: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

portion of tissue
type: Class
subclass of: multicellular structure
definition: Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.
database_cross_reference: CARO:0000043
database_cross_reference: UBERON:0000479
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007003
in subset: cur

Axiom
annotated source: portion of tissue
annotated property: definition
annotated target: Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

epithelium
type: Class
subclass of: portion of tissue
definition: Portion of tissue, that consists of one or more layers of cells with distinct apical-basal polarity, connected to each other by cell junctions.
database_cross_reference: UBERON:0000483
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007005
in subset: cur

Axiom
annotated source: epithelium
annotated property: definition
annotated target: Portion of tissue, that consists of one or more layers of cells with distinct apical-basal polarity, connected to each other by cell junctions.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

developing material anatomical entity
type: Class
subclass of: material anatomical entity
database_cross_reference: CARO:0000066
database_cross_reference: UBERON:0005423
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007006
in subset: cur

somatic precursor cell
type: Class
subclass of: developing material anatomical entity
subclass of: somatic cell
definition: Somatic cell that is a precursor to a mature cell.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007008
in subset: cur
in subset: scrnaseq slim

Axiom
annotated source: somatic precursor cell
annotated property: definition
annotated target: Somatic cell that is a precursor to a mature cell.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

organism subdivision
type: Class
subclass of: multicellular structure
definition: Anatomical structure that is a primary subdivision of whole organism. The mereological sum of these is the whole organism.
database_cross_reference: CARO:0000032
database_cross_reference: UBERON:0000475
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007009
in subset: cur
in subset: larval OF

Axiom
annotated source: organism subdivision
annotated property: definition
annotated target: Anatomical structure that is a primary subdivision of whole organism. The mereological sum of these is the whole organism.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

multi-tissue structure
type: Class
subclass of: multicellular structure
definition: Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which, through specific morphogenetic processes, forms a single distinct structural unit demarcated by bona fide boundaries from other distinct structural units of different types.
database_cross_reference: CARO:0000055
database_cross_reference: UBERON:0000481
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007010
in subset: cur
in subset: larval OF

Axiom
annotated source: multi-tissue structure
annotated property: definition
annotated target: Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which, through specific morphogenetic processes, forms a single distinct structural unit demarcated by bona fide boundaries from other distinct structural units of different types.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

female organism
type: Class
subclass of: organism
definition: Gonochoristic organism that can produce female gametes.
database_cross_reference: CARO:0000028
database_cross_reference: UBERON:0003100
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007011
in subset: cur

Axiom
annotated source: female organism
annotated property: definition
annotated target: Gonochoristic organism that can produce female gametes.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

acellular anatomical structure
type: Class
subclass of: anatomical structure
database_cross_reference: CARO:0000040
database_cross_reference: UBERON:0000476
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007013
in subset: cur

stem cell
type: Class
subclass of: cell
definition: Undifferentiated cell which retains its identity while budding off cells which differentiate.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007014
in subset: cur
in subset: expressionslim flybase ribbon

Axiom
annotated source: stem cell
annotated property: definition
annotated target: Undifferentiated cell which retains its identity while budding off cells which differentiate.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

material anatomical entity
type: Class
subclass of: anatomical entity
database_cross_reference: CARO:0000006
database_cross_reference: UBERON:0000465
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007016
in subset: cur
in subset: larval OF

cuboidal/columnar epithelium
type: Class
subclass of: epithelium
definition: An epithelium consisting of columnar shaped cells.
database_cross_reference: UBERON:0000485
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007027
in subset: cur

Axiom
annotated source: cuboidal/columnar epithelium
annotated property: definition
annotated target: An epithelium consisting of columnar shaped cells.
database_cross_reference: FlyBase:FBrf0239342

trunk ectoderm
type: Class
subclass of: developing embryonic structure
subclass of: Restriction
  on property: part of
  some values from: ectoderm
definition: The region of the ectoderm posterior to the cephalic furrow.
database_cross_reference: UBERON:6007045
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007045

Axiom
annotated source: trunk ectoderm
annotated property: definition
annotated target: The region of the ectoderm posterior to the cephalic furrow.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult cerebrum
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: part of
  some values from: adult central brain
subclass of: Restriction
  on property: part of
  some values from: adult cerebral ganglion
definition: The cerebral ganglion, minus the optic lobes. It includes part of the protocerebrum (without the optic lobes), the deutocerebrum and the tritocerebrum.
database_cross_reference: VFB:FBbt_00007050
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007050

Axiom
annotated source: adult cerebrum
annotated property: definition
annotated target: The cerebral ganglion, minus the optic lobes. It includes part of the protocerebrum (without the optic lobes), the deutocerebrum and the tritocerebrum.
database_cross_reference: FlyBase:FBrf0224194

adult lateral horn
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval lateral horn
definition: Dorsolateral horn-shaped synaptic neuropil domain of the adult protocerebrum that houses the terminals of various antennal lobe projection neurons (Ito et al., 2014). It is not separated from other neuropils by a glial sheath, but by the extent of arborization and synapsing of these antennal lobe projection neurons (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00007053
has exact synonym: LH
has OBO namespace: fly_anatomy.ontology
has related synonym: lateral protocerebrum
id: FBbt:00007053
in subset: BrainName

Axiom
annotated source: adult lateral horn
annotated property: definition
annotated target: Dorsolateral horn-shaped synaptic neuropil domain of the adult protocerebrum that houses the terminals of various antennal lobe projection neurons (Ito et al., 2014). It is not separated from other neuropils by a glial sheath, but by the extent of arborization and synapsing of these antennal lobe projection neurons (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult lateral horn
annotated property: hasExactSynonym
annotated target: LH
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: adult lateral horn
annotated property: hasRelatedSynonym
annotated target: lateral protocerebrum
database_cross_reference: FlyBase:FBrf0224194

superior lateral protocerebrum
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: part of
  some values from: superior neuropils
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval superior lateral protocerebrum
definition: Lateral synaptic neuropil domain of the adult superior neuropils. It lies behind the anterior optic tubercle, in front of the mushroom body calyx and above the superior clamp and lateral horn. Its boundary with the anterior optic tubercle (AOTU), mushroom body calyx and lateral horn is demarcated by the extent of arborization of visual projection neurons and antennal lobe projection neurons. Boundaries with the superior clamp, anterior and posterior ventro-lateral protocerebrum are defined using clearly distinguishable fiber bundles.
has alternative id: FBbt:00045031
database_cross_reference: VFB:FBbt_00007054
has exact synonym: SLP
has exact synonym: adult superior lateral protocerebrum
has OBO namespace: fly_anatomy.ontology
has related synonym: DLP
has related synonym: IDLP
has related synonym: slpr
id: FBbt:00007054
in subset: BrainName
comment: Boundaries defined by Ito et al. (2014) (used to define this term) differ slightly from those defined for slpr in Otsuna and Ito, 2006. The anterior superior SLP corresponds to mslpr and the posterior superior SLP to pslpr of Otsuna and Ito (2006). The SLP also corresponds to the lateral part of the dorsolateral protocerebrum (DLP) and lateral part of the inner dorsolateral protocerebrum (IDLP) of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: superior lateral protocerebrum
annotated property: definition
annotated target: Lateral synaptic neuropil domain of the adult superior neuropils. It lies behind the anterior optic tubercle, in front of the mushroom body calyx and above the superior clamp and lateral horn. Its boundary with the anterior optic tubercle (AOTU), mushroom body calyx and lateral horn is demarcated by the extent of arborization of visual projection neurons and antennal lobe projection neurons. Boundaries with the superior clamp, anterior and posterior ventro-lateral protocerebrum are defined using clearly distinguishable fiber bundles.
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00045031

Axiom
annotated source: superior lateral protocerebrum
annotated property: hasExactSynonym
annotated target: SLP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: superior lateral protocerebrum
annotated property: hasRelatedSynonym
annotated target: DLP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: superior lateral protocerebrum
annotated property: hasRelatedSynonym
annotated target: IDLP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: superior lateral protocerebrum
annotated property: hasRelatedSynonym
annotated target: slpr
database_cross_reference: FlyBase:FBrf0193607

ventrolateral protocerebrum
type: Class
subclass of: synaptic neuropil block
subclass of: Restriction
  on property: part of
  some values from: ventrolateral neuropils
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval ventrolateral protocerebrum
definition: A large mass of synaptic neuropil domains in the anterior brain of the adult, between the antennal lobe and the optic lobe (Ito et al., 2014). It can be divided into an anterior and posterior regions (AVLP and PVLP) (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00007058
has exact synonym: VLP
has exact synonym: anterior optic foci
has exact synonym: ventro-lateral adult protocerebrum
has exact synonym: ventro-lateral protocerebrum
has exact synonym: vlpr
has narrow synonym: OG
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007058
in subset: BrainName
comment: Currently some uncertainty about whether this is truly protocerebral - may actually be part of deutocerebrum (Strausfeld has characterized it as such). This should be clarified as a result of Volker Hartenstein's lineage mapping work. The VLP corresponds to almost all of the vlpr of Otsuna and Ito (2006) and to the ventrolateral protocerebrum (VLP) and optic glomerulus (OG) of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: ventrolateral protocerebrum
annotated property: definition
annotated target: A large mass of synaptic neuropil domains in the anterior brain of the adult, between the antennal lobe and the optic lobe (Ito et al., 2014). It can be divided into an anterior and posterior regions (AVLP and PVLP) (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: VLP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: vlpr
database_cross_reference: FlyBase:FBrf0193607

Axiom
annotated source: ventrolateral protocerebrum
annotated property: hasNarrowSynonym
annotated target: OG
database_cross_reference: FlyBase:FBrf0212704

anterior optic tubercle
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
subclass of: Restriction
  on property: part of
  some values from: ventrolateral neuropils
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval anterior optic tubercle primordial
definition: Synaptic neuropil domain of the adult protocerebrum that receives extensive arborizations from visual projection neurons from the lobula and the medulla, projecting via the anterior optic tract. It protrudes from the anterior-most area of the ventro-lateral neuropils and is slightly detached from the ventro-lateral protocerebrum. This neuropil is absent from the larval brain, being formed during pupal development.
database_cross_reference: VFB:FBbt_00007059
has exact synonym: AOTU
has exact synonym: OPTU
has exact synonym: OTU
has exact synonym: optic tubercle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007059
in subset: BrainName
comment: Otsuna and Ito (2006) suggest that the optic tubercle may be divided into three regions according to the density of arborizations. The medial-most (optu1) and lateral-most (optu3) contain dense arborizations of the Lcn10 neurons, whilst the area between these regions (optu2) is essentially devoid of the lobula columnar neurons.

Axiom
annotated source: anterior optic tubercle
annotated property: definition
annotated target: Synaptic neuropil domain of the adult protocerebrum that receives extensive arborizations from visual projection neurons from the lobula and the medulla, projecting via the anterior optic tract. It protrudes from the anterior-most area of the ventro-lateral neuropils and is slightly detached from the ventro-lateral protocerebrum. This neuropil is absent from the larval brain, being formed during pupal development.
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00007059

Axiom
annotated source: anterior optic tubercle
annotated property: hasExactSynonym
annotated target: AOTU
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: anterior optic tubercle
annotated property: hasExactSynonym
annotated target: OPTU
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: anterior optic tubercle
annotated property: hasExactSynonym
annotated target: OTU
database_cross_reference: FlyBase:FBrf0211884

multi-cell-component structure
type: Class
subclass of: anatomical structure
definition: A structure mainly consisting of cell components, rather than complete cells.
database_cross_reference: UBERON:0005162
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007060
in subset: larval OF
comment: May contain some complete cells in addition to partial ones (e.g. glia in nervous system regions).

Axiom
annotated source: multi-cell-component structure
annotated property: definition
annotated target: A structure mainly consisting of cell components, rather than complete cells.
database_cross_reference: https://orcid.org/0000-0002-1373-1705
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval ventromedial cerebrum
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: larval deutocerebrum
definition: One of a group of synaptic neuropil domains of the larval brain which are located ventral to the mushroom body and are grouped around the long axon tracts connecting the larval protocerebrum to the ventral nerve cord. This medially located compartment contacts the antennal lobe posteriorly. The lateral cervical tract ascends through the center of this compartment. It is the larval counterpart of the adult ventromedial neuropils.
database_cross_reference: VFB:FBbt_00007063
database_cross_reference: larvalbrain_neuropil:437
database_cross_reference: larvalbrain_neuropil:615
has exact synonym: BPM
has exact synonym: baso-posterior medial compartment
has exact synonym: basoposterior medial compartment
has exact synonym: larval VMC
has exact synonym: larval baso-posterior midbrain
has exact synonym: larval ventromedial cerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007063
comment: Note - description of relative location of brain structures in this definition is based on Younossi-Hartenstein et al., 2003 description of the first instar larval brain and Pereanu et al., 2010 third instar larval brain.

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: definition
annotated target: One of a group of synaptic neuropil domains of the larval brain which are located ventral to the mushroom body and are grouped around the long axon tracts connecting the larval protocerebrum to the ventral nerve cord. This medially located compartment contacts the antennal lobe posteriorly. The lateral cervical tract ascends through the center of this compartment. It is the larval counterpart of the adult ventromedial neuropils.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: hasExactSynonym
annotated target: BPM
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: hasExactSynonym
annotated target: basoposterior medial compartment
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: hasExactSynonym
annotated target: larval VMC
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval ventromedial cerebrum
annotated property: hasExactSynonym
annotated target: larval ventromedial cerebrum
database_cross_reference: FlyBase:FBrf0211016

embryonic/larval superior lateral protocerebrum
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: larval superior protocerebrum
definition: Thin layer of larval synaptic neuropil found lateral to the superior medial protocerebrum, separated from it by axon bundles of the DPlc lineages (Hartenstein et al., 2015). It is the precursor to the adult superior lateral protocerebrum and lateral horn domains (Pereanu et al., 2010; Hartenstein et al., 2015).
has broad synonym: CPLd
has broad synonym: dorsal centro-posterior lateral synaptic neuropil domain
database_cross_reference: VFB:FBbt_00007064
database_cross_reference: larvalbrain_neuropil:408
database_cross_reference: larvalbrain_neuropil:586
has exact synonym: larval SLP
has exact synonym: larval SLP/LH
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007064
in subset: larval OF

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: definition
annotated target: Thin layer of larval synaptic neuropil found lateral to the superior medial protocerebrum, separated from it by axon bundles of the DPlc lineages (Hartenstein et al., 2015). It is the precursor to the adult superior lateral protocerebrum and lateral horn domains (Pereanu et al., 2010; Hartenstein et al., 2015).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: hasBroadSynonym
annotated target: CPLd
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: hasBroadSynonym
annotated target: dorsal centro-posterior lateral synaptic neuropil domain
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: hasExactSynonym
annotated target: larval SLP
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval superior lateral protocerebrum
annotated property: hasExactSynonym
annotated target: larval SLP/LH
database_cross_reference: FlyBase:FBrf0229672

embryonic/larval ventrolateral protocerebrum
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: larval protocerebrum
definition: One of a group of synaptic neuropil domains of the larval brain which are located ventral to the mushroom body and are grouped around the long axon tracts connecting the larval protocerebrum to the ventral nerve cord. This compartment contacts the antennal lobe posteriorly, and is lateral to the lateral accessory lobe and ventromedial cerebrum. It grows anteriorly during larval development. It is the larval counterpart of the adult ventrolateral protocerebrum.
database_cross_reference: VFB:FBbt_00007068
database_cross_reference: larvalbrain_neuropil:422
database_cross_reference: larvalbrain_neuropil:600
has exact synonym: BPL
has exact synonym: baso-posterior lateral synaptic neuropil compartment
has exact synonym: baso-posterior lateral synaptic neuropil domain
has exact synonym: basoposterior lateral compartment
has exact synonym: larval VLP
has exact synonym: larval ventro-lateral protocerebrum
has exact synonym: larval ventrolateral protocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007068
comment: Developmental relation to adult synaptic neuropil domains comes from a personal communication from Volker Hartenstein. Note - description of relative location of brain structures in this definition is based on Younossi-Hartenstein et al., 2003 description of the first instar larval brain and Pereanu et al., 2010 third instar larval brain.

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: definition
annotated target: One of a group of synaptic neuropil domains of the larval brain which are located ventral to the mushroom body and are grouped around the long axon tracts connecting the larval protocerebrum to the ventral nerve cord. This compartment contacts the antennal lobe posteriorly, and is lateral to the lateral accessory lobe and ventromedial cerebrum. It grows anteriorly during larval development. It is the larval counterpart of the adult ventrolateral protocerebrum.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: BPL
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: basoposterior lateral compartment
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: larval VLP
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: larval ventrolateral protocerebrum
database_cross_reference: FlyBase:FBrf0211016

cell body rind of the central nervous system
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Superficial neuronal layer of the central nervous system, composed of glia and the cell bodies of neurons (soma). The cell body rind lies under the perineurium.
database_cross_reference: VFB:FBbt_00007114
has exact synonym: cortex of the central nervous system
has exact synonym: perikaryal rind
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007114

Axiom
annotated source: cell body rind of the central nervous system
annotated property: definition
annotated target: Superficial neuronal layer of the central nervous system, composed of glia and the cell bodies of neurons (soma). The cell body rind lies under the perineurium.
database_cross_reference: FlyBase:FBrf0239343

Axiom
annotated source: cell body rind of the central nervous system
annotated property: hasExactSynonym
annotated target: perikaryal rind
database_cross_reference: FlyBase:FBrf0207181

larval neuroblast
type: Class
equivalent class: Class
  intersection of: neuroblast
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: neuroblast
subclass of: Restriction
  on property: part of
  some values from: larval central nervous system
definition: Any neuroblast of the larva.
has broad synonym: embryonic/larval neuroblast
database_cross_reference: VFB:FBbt_00007115
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007115
in subset: cur

Axiom
annotated source: larval neuroblast
annotated property: definition
annotated target: Any neuroblast of the larva.
database_cross_reference: FlyBase:FBrf0047815

presumptive embryonic/larval system
type: Class
equivalent class: Class
  intersection of: non-connected developing system
  intersection of: Restriction
    on property: overlaps
    some values from: embryo
subclass of: developing embryonic structure
subclass of: non-connected developing system
definition: The sum of all the developing presumptive components of a specific embryonic/larval system in an embryo.
database_cross_reference: UBERON:6007116
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007116

Axiom
annotated source: presumptive embryonic/larval system
annotated property: definition
annotated target: The sum of all the developing presumptive components of a specific embryonic/larval system in an embryo.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

neuropil glial sheath
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Glial layer that largely surrounds a region of synaptic neuropil in the central nervous system (Younossi-Hartenstein et al., 2003). It is mainly formed by synaptic neuropil ensheathing glia, but these cells also frequently branch into neuropil domains and the layer also contains nuclei of reticular glia (Kremer et al., 2017).
database_cross_reference: VFB:FBbt_00007117
has exact synonym: glial boundary
has exact synonym: glial septum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007117

Axiom
annotated source: neuropil glial sheath
annotated property: definition
annotated target: Glial layer that largely surrounds a region of synaptic neuropil in the central nervous system (Younossi-Hartenstein et al., 2003). It is mainly formed by synaptic neuropil ensheathing glia, but these cells also frequently branch into neuropil domains and the layer also contains nuclei of reticular glia (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: neuropil glial sheath
annotated property: hasExactSynonym
annotated target: glial boundary
database_cross_reference: FlyBase:FBrf0206543

Axiom
annotated source: neuropil glial sheath
annotated property: hasExactSynonym
annotated target: glial septum
database_cross_reference: FlyBase:FBrf0155900

embryonic/larval periesophageal neuropils
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: overlaps
  some values from: larval tritocerebrum
definition: Larval counterpart to the adult periesophageal neuropils (Pereanu et al., 2010). It is located adjacent to the esophagus and guides the medial cervical tract (Younossi-Hartenstein et al., 2003; Hartenstein et al., 2015). Its anterior portion corresponds to the tritocerebrum (Hartenstein et al., 2015).
database_cross_reference: VFB:FBbt_00007129
has exact synonym: Bcv
has exact synonym: baso-cervical synaptic neuropil domain
has exact synonym: basocervical compartment
has exact synonym: larval PENP
has exact synonym: larval PONP
has exact synonym: larval periesophageal neuropils
has exact synonym: larval perioesophageal neuropils
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007129

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: definition
annotated target: Larval counterpart to the adult periesophageal neuropils (Pereanu et al., 2010). It is located adjacent to the esophagus and guides the medial cervical tract (Younossi-Hartenstein et al., 2003; Hartenstein et al., 2015). Its anterior portion corresponds to the tritocerebrum (Hartenstein et al., 2015).
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: Bcv
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: basocervical compartment
database_cross_reference: FlyBase:FBrf0155900

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: larval PENP
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: larval PONP
database_cross_reference: FlyBase:FBrf0211016

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: larval periesophageal neuropils
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval periesophageal neuropils
annotated property: hasExactSynonym
annotated target: larval perioesophageal neuropils
database_cross_reference: FlyBase:FBrf0211016

eye disc posterior to the morphogenetic furrow
type: Class
subclass of: portion of tissue
subclass of: Restriction
  on property: part of
  some values from: eye disc
definition: Portion of the eye disc which is posterior to the morphogenetic furrow. It contains developing ommatidial clusters whose maturity increases with distance posterior to the furrow.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007143

Axiom
annotated source: eye disc posterior to the morphogenetic furrow
annotated property: definition
annotated target: Portion of the eye disc which is posterior to the morphogenetic furrow. It contains developing ommatidial clusters whose maturity increases with distance posterior to the furrow.
database_cross_reference: FlyBase:FBrf0064798

adult protocerebrum
type: Class
equivalent class: Class
  intersection of: protocerebrum
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: protocerebrum
subclass of: adult neuromere
subclass of: Restriction
  on property: part of
  some values from: adult supraesophageal zone
subclass of: Restriction
  on property: overlaps
  some values from: adult ocular segment
subclass of: Restriction
  on property: overlaps
  some values from: adult labral segment
definition: Protocerebrum of the adult brain.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-06-13T10:49:41Z
database_cross_reference: UBERON:6007145
database_cross_reference: VFB:FBbt_00007145
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007145

Axiom
annotated source: adult protocerebrum
annotated property: definition
annotated target: Protocerebrum of the adult brain.
database_cross_reference: FlyBase:FBrf0224194

adult deutocerebrum
type: Class
equivalent class: Class
  intersection of: adult neuromere
  intersection of: Restriction
    on property: part of
    some values from: antennal segment
subclass of: deutocerebrum
subclass of: adult neuromere
subclass of: Restriction
  on property: part of
  some values from: adult antennal segment
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: overlaps
  some values from: adult supraesophageal zone
subclass of: Restriction
  on property: overlaps
  some values from: adult subesophageal zone
definition: Deutocerebrum of the adult brain. Substantial portions are below the level of the esophagus (Ito et al., 2014).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-06-13T10:52:46Z
database_cross_reference: VFB:FBbt_00007146
has exact synonym: adult deuterocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007146

Axiom
annotated source: adult deutocerebrum
annotated property: definition
annotated target: Deutocerebrum of the adult brain. Substantial portions are below the level of the esophagus (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult deutocerebrum
annotated property: hasExactSynonym
annotated target: adult deuterocerebrum
database_cross_reference: FlyBase:FBrf0224194

adult tritocerebrum
type: Class
equivalent class: Class
  intersection of: adult neuromere
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: tritocerebrum
subclass of: adult neuromere
subclass of: Restriction
  on property: part of
  some values from: adult intercalary segment
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: overlaps
  some values from: adult supraesophageal zone
subclass of: Restriction
  on property: overlaps
  some values from: adult subesophageal zone
definition: Tritocerebrum of the adult brain. Substantial portions are below the level of the esophagus (Ito et al., 2014).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-06-13T10:57:05Z
database_cross_reference: VFB:FBbt_00007147
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007147

Axiom
annotated source: adult tritocerebrum
annotated property: definition
annotated target: Tritocerebrum of the adult brain. Substantial portions are below the level of the esophagus (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0074226
database_cross_reference: FlyBase:FBrf0224194

sensillum
type: Class
equivalent class: Class
  intersection of: cell cluster organ
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: sense organ
subclass of: cell cluster organ
definition: A sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organized unit with a largely bona fide boundary.
database_cross_reference: UBERON:0002536
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007152
in subset: FB gloss
in subset: larval OF

Axiom
annotated source: sensillum
annotated property: definition
annotated target: A sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organized unit with a largely bona fide boundary.
database_cross_reference: FlyBase:FBrf0111704

cholinergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0014055
subclass of: CL_0000108
subclass of: neuron
definition: Any neuron (FBbt:00005106) that is capable of some acetylcholine secretion, neurotransmission (GO:0014055).
contributor: Q3074571
date: 2008-05-15T03:05:53Z
database_cross_reference: CL:0000108
database_cross_reference: VFB:FBbt_00007173
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007173
in subset: larval OF

Axiom
annotated source: cholinergic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some acetylcholine secretion, neurotransmission (GO:0014055).
database_cross_reference: FBC:Autogenerated

GABAergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0061534
subclass of: CL_0000617
subclass of: neuron
definition: Any neuron (FBbt:00005106) that is capable of some gamma-aminobutyric acid secretion, neurotransmission (GO:0061534).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-09-08T03:36:17Z
database_cross_reference: CL:0000617
database_cross_reference: VFB:FBbt_00007228
has exact synonym: GABA-ergic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007228
in subset: larval OF
comment: Some GABAergic neurons express ChAT transcripts (and reporters) at low levels, but do not produce functional enzyme (Lacin et al., 2019 - FBrf0242251).

Axiom
annotated source: GABAergic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some gamma-aminobutyric acid secretion, neurotransmission (GO:0061534).
database_cross_reference: FBC:Autogenerated

cell cluster organ
type: Class
subclass of: multicellular structure
definition: A cluster of cells of various types which form a discrete structure with a largely bona fide boundary.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-21T12:18:17Z
database_cross_reference: UBERON:0010001
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007229

Axiom
annotated source: cell cluster organ
annotated property: definition
annotated target: A cluster of cells of various types which form a discrete structure with a largely bona fide boundary.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

compound cell cluster organ
type: Class
subclass of: multicellular structure
definition: An anatomical structure consisting of multiple cell cluster organs and which does not contain portions of tissue.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-21T12:20:23Z
database_cross_reference: UBERON:0014732
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007230

Axiom
annotated source: compound cell cluster organ
annotated property: definition
annotated target: An anatomical structure consisting of multiple cell cluster organs and which does not contain portions of tissue.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

external sensillum
type: Class
subclass of: external sensory organ
subclass of: sensillum
subclass of: Restriction
  on property: develops from
  some values from: external sensory organ precursor cell I
definition: Sensillum which is embedded in the body wall and has a specific cuticular structure involved in the transduction of some sensory signal as a part.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-21T01:57:59Z
database_cross_reference: UBERON:6007231
database_cross_reference: VFB:FBbt_00007231
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007231
comment: This is a parent term for the mechanosensory bristles referred to as external sensilla (es) in some references e.g. Tsubouchi et al., 2017 (FBrf0237124), but also includes other modalities.

Axiom
annotated source: external sensillum
annotated property: definition
annotated target: Sensillum which is embedded in the body wall and has a specific cuticular structure involved in the transduction of some sensory signal as a part.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

internal sensillum
type: Class
subclass of: sensillum
subclass of: internal sense organ
definition: Sensillum that is internal to the animal - i.e. having no part that is part of the cuticle.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-21T02:04:23Z
database_cross_reference: UBERON:6007233
database_cross_reference: VFB:FBbt_00007233
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007233

Axiom
annotated source: internal sensillum
annotated property: definition
annotated target: Sensillum that is internal to the animal - i.e. having no part that is part of the cuticle.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

compound sense organ
type: Class
equivalent class: Class
  intersection of: compound cell cluster organ
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: sense organ
subclass of: compound cell cluster organ
definition: Any compound cell cluster organ (FBbt:00007230) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-21T02:09:38Z
has alternative id: FBbt:00002653
has exact synonym: compound sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007234

Axiom
annotated source: compound sense organ
annotated property: definition
annotated target: Any compound cell cluster organ (FBbt:00007230) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
database_cross_reference: FBC:Autogenerated

external compound sense organ
type: Class
subclass of: external sensory organ
subclass of: compound sense organ
definition: Compound sense organ that is located within the epidermis.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-21T02:23:08Z
database_cross_reference: VFB:FBbt_00007235
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007235

Axiom
annotated source: external compound sense organ
annotated property: definition
annotated target: Compound sense organ that is located within the epidermis.
database_cross_reference: FlyBase:FBrf0089570

adult sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult sense organ
subclass of: sensillum
definition: Any sensillum of the adult.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-22T09:42:58Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007239

Axiom
annotated source: adult sensillum
annotated property: definition
annotated target: Any sensillum of the adult.
database_cross_reference: FBC:Autogenerated

larval sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval sense organ
subclass of: sensillum
definition: Any sensillum of the larva.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-22T09:42:58Z
database_cross_reference: UBERON:6007240
has exact synonym: embryonic/larval sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007240

Axiom
annotated source: larval sensillum
annotated property: definition
annotated target: Any sensillum of the larva.
database_cross_reference: FBC:Autogenerated

adult head sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: adult head
subclass of: head sensillum
subclass of: adult sensillum
subclass of: Restriction
  on property: part of
  some values from: adult head
definition: Any sensillum (FBbt:00007152) that is part of some adult head (FBbt:00003007).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-22T09:42:58Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007241

Axiom
annotated source: adult head sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some adult head (FBbt:00003007).
database_cross_reference: FBC:Autogenerated

embryonic/larval head sensillum
type: Class
equivalent class: Class
  intersection of: sensillum
  intersection of: Restriction
    on property: part of
    some values from: larval head
subclass of: head sensillum
subclass of: larval sensillum
subclass of: embryonic/larval head sense organ
definition: Any sensillum (FBbt:00007152) that is part of some larval head (FBbt:00001730).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-22T09:42:58Z
database_cross_reference: UBERON:6007242
has exact synonym: larval head sensillum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007242

Axiom
annotated source: embryonic/larval head sensillum
annotated property: definition
annotated target: Any sensillum (FBbt:00007152) that is part of some larval head (FBbt:00001730).
database_cross_reference: FBC:Autogenerated

cuticular specialization
type: Class
subclass of: acellular anatomical structure
subclass of: Restriction
  on property: part of
  some values from: cuticle
definition: Specialized structure that is found on the cuticle.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-10-22T02:20:05Z
database_cross_reference: UBERON:6007245
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007245

Axiom
annotated source: cuticular specialization
annotated property: definition
annotated target: Specialized structure that is found on the cuticle.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

rhabdomeric photoreceptor cell
type: Class
subclass of: photoreceptor neuron
definition: Photoreceptor cell that contains rhabdomeres.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-11-03T01:07:44Z
database_cross_reference: VFB:FBbt_00007251
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007251

Axiom
annotated source: rhabdomeric photoreceptor cell
annotated property: definition
annotated target: Photoreceptor cell that contains rhabdomeres.
database_cross_reference: FlyBase:FBrf0064802

disconnected anatomical group
type: Class
subclass of: material anatomical entity
definition: Material anatomical entity generated by coordinated expression of the organism's own genome and whose component parts are not all continuous with each other.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-11-04T03:09:28Z
database_cross_reference: UBERON:0034923
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007276

Axiom
annotated source: disconnected anatomical group
annotated property: definition
annotated target: Material anatomical entity generated by coordinated expression of the organism's own genome and whose component parts are not all continuous with each other.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

anatomical cluster
type: Class
subclass of: disconnected anatomical group
definition: Anatomical group whose component anatomical structures lie in close proximity to each other.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-11-04T03:13:41Z
database_cross_reference: UBERON:0000477
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007277

Axiom
annotated source: anatomical cluster
annotated property: definition
annotated target: Anatomical group whose component anatomical structures lie in close proximity to each other.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

non-connected functional system
type: Class
subclass of: disconnected anatomical group
definition: An anatomical group whose component structures share a common function.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-11-04T03:18:01Z
database_cross_reference: UBERON:0015203
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007278

Axiom
annotated source: non-connected functional system
annotated property: definition
annotated target: An anatomical group whose component structures share a common function.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval head sense organ
type: Class
equivalent class: Class
  intersection of: sense organ
  intersection of: Restriction
    on property: part of
    some values from: larval head
subclass of: larval sense organ
subclass of: Restriction
  on property: part of
  some values from: larval head
definition: Any sense organ (FBbt:00005155) that is part of some larval head (FBbt:00001730).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-11-05T10:34:14Z
database_cross_reference: UBERON:6007280
database_cross_reference: VFB:FBbt_00007280
has exact synonym: larval head sense organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007280

Axiom
annotated source: embryonic/larval head sense organ
annotated property: definition
annotated target: Any sense organ (FBbt:00005155) that is part of some larval head (FBbt:00001730).
database_cross_reference: FBC:Autogenerated

integumentary specialization
type: Class
subclass of: anatomical entity
subclass of: Restriction
  on property: part of
  some values from: integumentary system
definition: Specialized structure that is found on the integument.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-11-06T03:13:52Z
database_cross_reference: UBERON:6007288
has exact synonym: integumentary specialisation
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007288

Axiom
annotated source: integumentary specialization
annotated property: definition
annotated target: Specialized structure that is found on the integument.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

embryonic/larval head nerve
type: Class
equivalent class: Class
  intersection of: nerve
  intersection of: Restriction
    on property: part of
    some values from: larval head
subclass of: nerve
subclass of: Restriction
  on property: part of
  some values from: larval head
definition: Any nerve (FBbt:00005105) that is part of some larval head (FBbt:00001730).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-11-20T07:54:36Z
database_cross_reference: VFB:FBbt_00007318
has exact synonym: larval head nerve
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007318

Axiom
annotated source: embryonic/larval head nerve
annotated property: definition
annotated target: Any nerve (FBbt:00005105) that is part of some larval head (FBbt:00001730).
database_cross_reference: FBC:Autogenerated

organ system subdivision
type: Class
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: organ system
definition: Any subdivision of an organ system.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-12-12T07:22:29Z
database_cross_reference: UBERON:0011216
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007330

Axiom
annotated source: organ system subdivision
annotated property: definition
annotated target: Any subdivision of an organ system.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

segmental subdivision of organ system
type: Class
subclass of: organ system subdivision
definition: The part of some organism that is part of some specified segment.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-12-12T07:22:57Z
database_cross_reference: UBERON:6007331
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007331

Axiom
annotated source: segmental subdivision of organ system
annotated property: definition
annotated target: The part of some organism that is part of some specified segment.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval intercalary segment sense organ
type: Class
equivalent class: Class
  intersection of: larval sense organ
  intersection of: Restriction
    on property: part of
    some values from: intercalary segment
subclass of: intercalary segment sense organ
subclass of: embryonic/larval head sense organ
subclass of: Restriction
  on property: part of
  some values from: larval intercalary segment
definition: Any larval sense organ (FBbt:00002639) that is part of some intercalary segment (FBbt:00000010).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-02-27T03:34:39Z
database_cross_reference: VFB:FBbt_00007335
has exact synonym: larval intercalary segment sense organ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007335

Axiom
annotated source: embryonic/larval intercalary segment sense organ
annotated property: definition
annotated target: Any larval sense organ (FBbt:00002639) that is part of some intercalary segment (FBbt:00000010).
database_cross_reference: FBC:Autogenerated

somatic stem cell
type: Class
subclass of: somatic precursor cell
subclass of: stem cell
definition: Stem cell that is a progenitor of somatic cells.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-06-25T05:38:39Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007344

Axiom
annotated source: somatic stem cell
annotated property: definition
annotated target: Stem cell that is a progenitor of somatic cells.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

histaminergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0061538
subclass of: CL_0011110
subclass of: aminergic neuron
definition: Any neuron (FBbt:00005106) that is capable of some histamine secretion, neurotransmission (GO:0061538).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-07-13T03:28:45Z
database_cross_reference: CL:0011110
database_cross_reference: VFB:FBbt_00007367
has exact synonym: HA-IR neuron
has exact synonym: HAIR neuron
has exact synonym: histaminelike immunoreactive neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007367

Axiom
annotated source: histaminergic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some histamine secretion, neurotransmission (GO:0061538).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: histaminergic neuron
annotated property: hasExactSynonym
annotated target: HA-IR neuron
database_cross_reference: FlyBase:FBrf0052427

Axiom
annotated source: histaminergic neuron
annotated property: hasExactSynonym
annotated target: HAIR neuron
database_cross_reference: FlyBase:FBrf0055596

Axiom
annotated source: histaminergic neuron
annotated property: hasExactSynonym
annotated target: histaminelike immunoreactive neuron
database_cross_reference: FlyBase:FBrf0052427

aminergic neuron
type: Class
subclass of: neuron
definition: A neuron that uses a biogenic amine as its neurotransmitter (Vomel and Wegener, 2008; Fuchs et al., 2014).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-07-13T04:06:57Z
database_cross_reference: VFB:FBbt_00007368
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007368
comment: Strictly speaking, "aminergic" should refer to any type of amine being used as a neurotransmitter. However, the term is most commonly used to refer to biogenic amines only, which is the meaning we retain here. See https://github.com/geneontology/go-ontology/issues/21625.

Axiom
annotated source: aminergic neuron
annotated property: definition
annotated target: A neuron that uses a biogenic amine as its neurotransmitter (Vomel and Wegener, 2008; Fuchs et al., 2014).
database_cross_reference: FlyBase:FBrf0210246
database_cross_reference: doi:10.1038/srep05526

internal sense organ
type: Class
subclass of: sense organ
definition: Sense organ that is internal to the animal - i.e. having no part that is part of the cuticle.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-10-19T02:27:41Z
database_cross_reference: UBERON:6007373
database_cross_reference: VFB:FBbt_00007373
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007373

Axiom
annotated source: internal sense organ
annotated property: definition
annotated target: Sense organ that is internal to the animal - i.e. having no part that is part of the cuticle.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

projection neuron
type: Class
subclass of: input/output neuron
subclass of: Restriction
  on property: overlaps
  some values from: neuropil
definition: An interneuron that projects from some primary sensory neuropil (e.g. the antennal lobe) to a higher neuropil region.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-12-14T01:22:39Z
database_cross_reference: VFB:FBbt_00007392
has exact synonym: 2nd-order PN
has exact synonym: PN
has exact synonym: second order projection neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007392

Axiom
annotated source: projection neuron
annotated property: definition
annotated target: An interneuron that projects from some primary sensory neuropil (e.g. the antennal lobe) to a higher neuropil region.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: projection neuron
annotated property: hasExactSynonym
annotated target: 2nd-order PN
database_cross_reference: FlyBase:FBrf0255988

Axiom
annotated source: projection neuron
annotated property: hasExactSynonym
annotated target: PN
database_cross_reference: FlyBase:FBrf0219809

Axiom
annotated source: projection neuron
annotated property: hasExactSynonym
annotated target: second order projection neuron
database_cross_reference: FlyBase:FBrf0255988

fascicle
type: Class
equivalent class: Class
  intersection of: tract
  intersection of: Restriction
    on property: has characteristic
    some values from: PATO_0000634
subclass of: tract
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0000634
definition: A tract of the central nervous system that does not cross the midline.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-03-10T11:43:43Z
database_cross_reference: VFB:FBbt_00007426
has exact synonym: ipsilateral tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007426
in subset: FB gloss
in subset: cur

Axiom
annotated source: fascicle
annotated property: definition
annotated target: A tract of the central nervous system that does not cross the midline.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval gut
type: Class
equivalent class: Class
  intersection of: gut
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: gut
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval alimentary canal
definition: Structure consisting of the embryonic/larval foregut, midgut and hindgut.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-10-04T09:58:25Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007512

Axiom
annotated source: embryonic/larval gut
annotated property: definition
annotated target: Structure consisting of the embryonic/larval foregut, midgut and hindgut.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult gut
type: Class
equivalent class: Class
  intersection of: gut
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: gut
subclass of: Restriction
  on property: part of
  some values from: adult alimentary canal
definition: Structure consisting of a simple epithelium surrounded by visceral muscles, nerves and tracheae. The adult gut is divided into the adult foregut, midgut and hindgut regions, based on developmental origin.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-10-04T11:02:39Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007513

Axiom
annotated source: adult gut
annotated property: definition
annotated target: Structure consisting of a simple epithelium surrounded by visceral muscles, nerves and tracheae. The adult gut is divided into the adult foregut, midgut and hindgut regions, based on developmental origin.
database_cross_reference: FlyBase:FBrf0223413
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult optic lobe intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: adult optic lobe
subclass of: adult visual neuropil intrinsic neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: adult optic lobe
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: adult optic lobe
subclass of: Restriction
  on property: synapses restricted to region
  some values from: adult optic lobe
definition: Any neuron (FBbt:00005106) that synapses restricted to region some adult optic lobe (FBbt:00003701).
database_cross_reference: VFB:FBbt_00007577
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007577

Axiom
annotated source: adult optic lobe intrinsic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that synapses restricted to region some adult optic lobe (FBbt:00003701).
database_cross_reference: FBC:Autogenerated

optic lobe intrinsic columnar neuron
type: Class
subclass of: adult optic lobe neuron
subclass of: adult optic lobe columnar neuron
subclass of: adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
definition: A columnar neuron whose arborizations are restricted to the adult optic lobe.
database_cross_reference: VFB:FBbt_00007578
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007578

Axiom
annotated source: optic lobe intrinsic columnar neuron
annotated property: definition
annotated target: A columnar neuron whose arborizations are restricted to the adult optic lobe.
database_cross_reference: FlyBase:FBrf0049410

optic lobe tangential neuron
type: Class
subclass of: adult interneuron
subclass of: Restriction
  on property: has soma location
  some values from: adult brain cell body rind
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: adult optic lobe
definition: Interneuron that is oriented perpendicular to the columns of adult optic lobe neuropils and has a major projection along the plane of a layer of optic lobe neuropil.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2011-02-08T02:25:10Z
database_cross_reference: VFB:FBbt_00007579
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007579

Axiom
annotated source: optic lobe tangential neuron
annotated property: definition
annotated target: Interneuron that is oriented perpendicular to the columns of adult optic lobe neuropils and has a major projection along the plane of a layer of optic lobe neuropil.
database_cross_reference: FlyBase:FBrf0049410

optic glomerulus of the PLP
type: Class
equivalent class: Class
  intersection of: optic glomerulus
  intersection of: Restriction
    on property: part of
    some values from: posterior lateral protocerebrum
subclass of: optic glomerulus
subclass of: Restriction
  on property: part of
  some values from: posterior lateral protocerebrum
definition: Any optic glomerulus (FBbt:00003698) that is part of some posterior lateral protocerebrum (FBbt:00040044).
database_cross_reference: VFB:FBbt_00007581
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007581

Axiom
annotated source: optic glomerulus of the PLP
annotated property: definition
annotated target: Any optic glomerulus (FBbt:00003698) that is part of some posterior lateral protocerebrum (FBbt:00040044).
database_cross_reference: FlyBase:FBrf0246888

optic glomerulus of the PVLP
type: Class
equivalent class: Class
  intersection of: optic glomerulus
  intersection of: Restriction
    on property: part of
    some values from: posterior ventrolateral protocerebrum
subclass of: optic glomerulus
subclass of: Restriction
  on property: part of
  some values from: posterior ventrolateral protocerebrum
definition: Any optic glomerulus (FBbt:00003698) that is part of some posterior ventrolateral protocerebrum (FBbt:00040042).
database_cross_reference: VFB:FBbt_00007582
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007582

Axiom
annotated source: optic glomerulus of the PVLP
annotated property: definition
annotated target: Any optic glomerulus (FBbt:00003698) that is part of some posterior ventrolateral protocerebrum (FBbt:00040042).
database_cross_reference: FlyBase:FBrf0246888

trichome field
type: Class
subclass of: BFO_0000040
subclass of: anatomical cluster
subclass of: Restriction
  on property: composed primarily of
  some values from: trichome
definition: A group of trichomes covering a region of integument.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007658

Axiom
annotated source: trichome field
annotated property: definition
annotated target: A group of trichomes covering a region of integument.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

optic column
type: Class
subclass of: synaptic neuropil segment
definition: A subdivision of the optic lobe neuropil that maps to a single ommatidium. In the lamina and distal medulla these correspond to the projections and arborization of photoreceptor cells. Narrow field columnar neurons define continuation of these columns medial to this.
database_cross_reference: VFB:FBbt_00007659
has exact synonym: neuro-ommatidium
has exact synonym: visual column
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007659

Axiom
annotated source: optic column
annotated property: definition
annotated target: A subdivision of the optic lobe neuropil that maps to a single ommatidium. In the lamina and distal medulla these correspond to the projections and arborization of photoreceptor cells. Narrow field columnar neurons define continuation of these columns medial to this.
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: optic column
annotated property: hasExactSynonym
annotated target: neuro-ommatidium
database_cross_reference: FlyBase:FBrf0049410

Axiom
annotated source: optic column
annotated property: hasExactSynonym
annotated target: visual column
database_cross_reference: FlyBase:FBrf0049410

larval optic anlage
type: Class
subclass of: anlage
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: embryonic optic lobe primordium
definition: An anlage that is a precursor of some part of the adult optic lobe in the larva. It develops from the embryonic optic lobe primordium.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2013-03-13T02:59:16Z
database_cross_reference: VFB:FBbt_00007676
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007676

Axiom
annotated source: larval optic anlage
annotated property: definition
annotated target: An anlage that is a precursor of some part of the adult optic lobe in the larva. It develops from the embryonic optic lobe primordium.
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: https://orcid.org/0000-0002-7073-9172

sensory system
type: Class
equivalent class: Class
  intersection of: non-connected functional system
  intersection of: Restriction
    on property: capable of
    some values from: GO_0007600
subclass of: BFO_0000040
subclass of: non-connected functional system
subclass of: Restriction
  on property: overlaps
  some values from: nervous system
subclass of: Restriction
  on property: capable of
  some values from: GO_0007600
definition: An anatomical system consisting of all of the anatomical entities that function in some part of the sensory perception.
database_cross_reference: UBERON:0001032
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007692
in subset: expressionslim flybase ribbon
comment: Note - the relationship of this class to the nervous system is overlap. This allows for sense organ components that function in the transduction of sensory signals but that are not considered to be part of the nervous system to be part of sensory systems.

Axiom
annotated source: sensory system
annotated property: definition
annotated target: An anatomical system consisting of all of the anatomical entities that function in some part of the sensory perception.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

sensory system neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of part of
    some values from: GO_0007600
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: sensory system
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0007600
definition: Any neuron (FBbt:00005106) that capable of part of some sensory perception (GO:0007600).
database_cross_reference: VFB:FBbt_00007693
has OBO namespace: fly_anatomy.ontology
id: FBbt:00007693

Axiom
annotated source: sensory system neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that capable of part of some sensory perception (GO:0007600).
database_cross_reference: https://orcid.org/0000-0001-5948-3092

distal medullary amacrine neuron Dm8a
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm8a
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla sublayer M6A
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla sublayer M6A
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R7
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm5c
IAO_0000028: Dm8a
definition: Glutamatergic (Gao et al., 2008; Karuppudurai et al., 2014) distal medullary amacrine neuron that branches extensively in medulla layer M6A (Fischbach and Dittrich, 1989; Takemura et al., 2013; Nern et al., 2015), spanning approximately 16 medulla columns (Karuppudurai et al., 2014), with centrifugal projections back to layer M4 (Takemura et al., 2013; Nern et al., 2015). The highest arbor density and longest distal projection are usually found in one optic column (its 'home column'), near the center of the M6A arborization, with these columns tiling between different individual Dm8 cells, while the rest of the arbor overlaps with other Dm8 cells considerably (Gao et al., 2008; Nern et al., 2015; Kind et al., 2021). In layer M6, it is postsynaptic to several R7 photoreceptor cells and presynaptic to Tm5c (Gao et al., 2008; Takemura et al., 2013; Karuppudurai et al., 2014). The contacts with Tm5c are clustered in one column at the center of the dendritic field of Dm8 (Karuppudurai et al., 2014). It is involved in UV preference (Gao et al., 2008).
database_cross_reference: FlyBrain_NDB:10088
database_cross_reference: VFB:FBbt_00013774
has exact synonym: Dm8
has exact synonym: Dm8a
has exact synonym: distal medullary amacrine neuron Dm8
has OBO namespace: fly_anatomy.ontology
id: FBbt:00013774
in subset: cur
comment: Connectivity inferred from EM reconstructions from a single EM section. The neurotransmitter was assessed in cells labelled with a glutamate GAL4 driver P\{GawB}vGlut[OK371] (FBti0076967) (Gao et al., 2008), RT-PCR and by immunohistochemistry (Karuppudurai et al., 2014). Connectivity with R7 was assessed by EM reconstruction of a single medulla column (Gao et al., 2008) or reconstruction of serial-section TEM (Takemura et al., 2013).

Axiom
annotated source: distal medullary amacrine neuron Dm8a
annotated property: IAO_0000028
annotated target: Dm8a
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: distal medullary amacrine neuron Dm8a
annotated property: definition
annotated target: Glutamatergic (Gao et al., 2008; Karuppudurai et al., 2014) distal medullary amacrine neuron that branches extensively in medulla layer M6A (Fischbach and Dittrich, 1989; Takemura et al., 2013; Nern et al., 2015), spanning approximately 16 medulla columns (Karuppudurai et al., 2014), with centrifugal projections back to layer M4 (Takemura et al., 2013; Nern et al., 2015). The highest arbor density and longest distal projection are usually found in one optic column (its 'home column'), near the center of the M6A arborization, with these columns tiling between different individual Dm8 cells, while the rest of the arbor overlaps with other Dm8 cells considerably (Gao et al., 2008; Nern et al., 2015; Kind et al., 2021). In layer M6, it is postsynaptic to several R7 photoreceptor cells and presynaptic to Tm5c (Gao et al., 2008; Takemura et al., 2013; Karuppudurai et al., 2014). The contacts with Tm5c are clustered in one column at the center of the dendritic field of Dm8 (Karuppudurai et al., 2014). It is involved in UV preference (Gao et al., 2008).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: distal medullary amacrine neuron Dm8a
annotated property: hasExactSynonym
annotated target: Dm8
database_cross_reference: FlyBase:FBrf0213020

Axiom
annotated source: distal medullary amacrine neuron Dm8a
annotated property: hasExactSynonym
annotated target: Dm8a
database_cross_reference: FlyBase:FBrf0262545
has synonym type: VFB SYMBOL

Axiom
annotated source: distal medullary amacrine neuron Dm8a
annotated property: hasExactSynonym
annotated target: distal medullary amacrine neuron Dm8
database_cross_reference: FlyBase:FBrf0213020

wide field transmedullary neuron
type: Class
subclass of: transmedullary neuron
subclass of: optic lobe wide-field columnar neuron
definition: A transmedullary neuron that arborizes across multiple columns.
database_cross_reference: VFB:FBbt_00013788
has OBO namespace: fly_anatomy.ontology
id: FBbt:00013788

Axiom
annotated source: wide field transmedullary neuron
annotated property: definition
annotated target: A transmedullary neuron that arborizes across multiple columns.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652

narrow field transmedullary neuron
type: Class
subclass of: transmedullary neuron
subclass of: optic lobe narrow field columnar neuron
definition: A transmedullary neuron whose arborizations are mostly restricted to a single column.
database_cross_reference: VFB:FBbt_00013789
has OBO namespace: fly_anatomy.ontology
id: FBbt:00013789

Axiom
annotated source: narrow field transmedullary neuron
annotated property: definition
annotated target: A transmedullary neuron whose arborizations are mostly restricted to a single column.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652

early extended germ band embryo
type: Class
subclass of: extended germ band embryo
definition: A collective term for stages 9 and 10.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00014201
in subset: cur

Axiom
annotated source: early extended germ band embryo
annotated property: definition
annotated target: A collective term for stages 9 and 10.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral trunk epidermis primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral epidermis primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic ventral trunk epidermis
definition: Primordium of the ventral trunk epidermis of the late extended germ band and dorsal closure embryo that will give rise to the embryonic ventral trunk epidermis.
has exact synonym: P1 VenEp
has OBO namespace: fly_anatomy.ontology
id: FBbt:00016007
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral trunk epidermis primordium
annotated property: definition
annotated target: Primordium of the ventral trunk epidermis of the late extended germ band and dorsal closure embryo that will give rise to the embryonic ventral trunk epidermis.
database_cross_reference: FBC:VH

Axiom
annotated source: ventral trunk epidermis primordium
annotated property: hasExactSynonym
annotated target: P1 VenEp
database_cross_reference: https://orcid.org/0000-0002-7073-9172

anal pad primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral epidermis primordium
subclass of: Restriction
  on property: develops into
  some values from: embryonic anal pad
definition: Primordium of the anal pad of the late extended germ band and dorsal closure embryo that will give rise to the embryonic anal pads.
has OBO namespace: fly_anatomy.ontology
has related synonym: A/P1 AnPd
has related synonym: anal pad specific anlage
id: FBbt:00016008
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: anal pad primordium
annotated property: definition
annotated target: Primordium of the anal pad of the late extended germ band and dorsal closure embryo that will give rise to the embryonic anal pads.
database_cross_reference: FBC:VH

Axiom
annotated source: anal pad primordium
annotated property: hasRelatedSynonym
annotated target: A/P1 AnPd
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral apodeme anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral epidermis primordium
subclass of: Restriction
  on property: develops into
  some values from: ventral apodeme primordium
definition: Anlage of the ventral apodeme of the late extended germ band embryo that will give rise to the ventral apodeme primordium.
has exact synonym: A venApo
has OBO namespace: fly_anatomy.ontology
id: FBbt:00016009
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral apodeme anlage
annotated property: definition
annotated target: Anlage of the ventral apodeme of the late extended germ band embryo that will give rise to the ventral apodeme primordium.
database_cross_reference: FBC:VH

Axiom
annotated source: ventral apodeme anlage
annotated property: hasExactSynonym
annotated target: A venApo
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral apodeme primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral apodeme anlage
subclass of: Restriction
  on property: develops into
  some values from: embryonic ventral apodeme
definition: Primordium of the ventral apodeme of the dorsal closure embryo that will give rise to the ventral apodemes.
has exact synonym: P1 venApo
has OBO namespace: fly_anatomy.ontology
has related synonym: ventral apodeme specific primordium
id: FBbt:00016010
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: ventral apodeme primordium
annotated property: definition
annotated target: Primordium of the ventral apodeme of the dorsal closure embryo that will give rise to the ventral apodemes.
database_cross_reference: FBC:VH

Axiom
annotated source: ventral apodeme primordium
annotated property: hasExactSynonym
annotated target: P1 venApo
database_cross_reference: https://orcid.org/0000-0002-7073-9172

denticle field primordium
type: Class
subclass of: developing embryonic structure
subclass of: primordium
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: dorsal closure embryo
subclass of: Restriction
  on property: develops from
  some values from: denticle field anlage
subclass of: Restriction
  on property: develops into
  some values from: denticle field
definition: Primordium of the denticle field of the dorsal closure embryo that will give rise to the larval denticle fields.
has exact synonym: P DenBl
has OBO namespace: fly_anatomy.ontology
id: FBbt:00016011
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: denticle field primordium
annotated property: definition
annotated target: Primordium of the denticle field of the dorsal closure embryo that will give rise to the larval denticle fields.
database_cross_reference: FBC:VH

Axiom
annotated source: denticle field primordium
annotated property: hasExactSynonym
annotated target: P DenBl
database_cross_reference: https://orcid.org/0000-0002-7073-9172

denticle field
type: Class
subclass of: trichome field
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval cuticle
subclass of: Restriction
  on property: develops from
  some values from: denticle field primordium
definition: Region of embryonic and larval ventral cuticle that displays denticle belts. It develops from the denticle field primordium.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00016012
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: denticle field
annotated property: definition
annotated target: Region of embryonic and larval ventral cuticle that displays denticle belts. It develops from the denticle field primordium.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570

ectodermal derivative
type: Class
equivalent class: Class
  intersection of: anatomical entity
  intersection of: Restriction
    on property: develops from
    some values from: ectoderm
subclass of: germ layer derivative
subclass of: Restriction
  on property: develops from
  some values from: ectoderm
definition: Any anatomical entity (FBbt:10000000) that develops from some ectoderm (FBbt:00000111).
has alternative id: FBbt:00005253
has OBO namespace: fly_anatomy.ontology
id: FBbt:00025990
in subset: cur

Axiom
annotated source: ectodermal derivative
annotated property: definition
annotated target: Any anatomical entity (FBbt:10000000) that develops from some ectoderm (FBbt:00000111).
database_cross_reference: FlyBase:FBrf0043441
database_cross_reference: FlyBase:FBrf0053832

anterior ectoderm derivative
type: Class
equivalent class: Class
  intersection of: anatomical entity
  intersection of: Restriction
    on property: develops from
    some values from: anterior ectoderm
subclass of: ectodermal derivative
subclass of: Restriction
  on property: develops from
  some values from: anterior ectoderm
definition: Any anatomical entity (FBbt:10000000) that develops from some anterior ectoderm (FBbt:00000119).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00025991
in subset: cur

Axiom
annotated source: anterior ectoderm derivative
annotated property: definition
annotated target: Any anatomical entity (FBbt:10000000) that develops from some anterior ectoderm (FBbt:00000119).
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventral ectoderm derivative
type: Class
equivalent class: Class
  intersection of: anatomical entity
  intersection of: Restriction
    on property: develops from
    some values from: ventral ectoderm
subclass of: ectodermal derivative
subclass of: Restriction
  on property: develops from
  some values from: ventral ectoderm
definition: Any anatomical entity (FBbt:10000000) that develops from some ventral ectoderm (FBbt:00005558).
has OBO namespace: fly_anatomy.ontology
id: FBbt:00025993
in subset: cur

Axiom
annotated source: ventral ectoderm derivative
annotated property: definition
annotated target: Any anatomical entity (FBbt:10000000) that develops from some ventral ectoderm (FBbt:00005558).
database_cross_reference: https://orcid.org/0000-0002-7073-9172

ventromedial neuropils
type: Class
subclass of: synaptic neuropil block
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval ventromedial cerebrum
definition: A group of synaptic neuropil domains in the adult brain located above or and lateral to the esophagus, below the mushroom body calyx and inferior neuropils, behind the lateral accessory lobe and medial to the ventrolateral neuropils.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-12T04:32:55Z
database_cross_reference: VFB:FBbt_00040002
has exact synonym: VMNP
has exact synonym: VMNPS
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040002
in subset: BrainName
comment: Despite the name, intended as a singular noun as in "The United States".

Axiom
annotated source: ventromedial neuropils
annotated property: definition
annotated target: A group of synaptic neuropil domains in the adult brain located above or and lateral to the esophagus, below the mushroom body calyx and inferior neuropils, behind the lateral accessory lobe and medial to the ventrolateral neuropils.
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: ventromedial neuropils
annotated property: hasExactSynonym
annotated target: VMNP
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: ventromedial neuropils
annotated property: hasExactSynonym
annotated target: VMNPS
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

non-connected developing system
type: Class
subclass of: developing material anatomical entity
subclass of: disconnected anatomical group
definition: The sum of all the anlagen and primordia that will develop into a single system.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-04-29T07:57:11Z
database_cross_reference: UBERON:6040003
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040003
comment: Note - this may be the precursor of a connected system that starts out non-connected, such as the tracheal system, or of a system that remains disconnected, e.g. functionally defined systems such as the endocrine system.

Axiom
annotated source: non-connected developing system
annotated property: definition
annotated target: The sum of all the anlagen and primordia that will develop into a single system.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

tract neuropil
type: Class
subclass of: disconnected anatomical group
subclass of: Restriction
  on property: part of
  some values from: neuropil
definition: The part of the neuropil consisting largely of neuron projections without synapses.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-12T06:11:19Z
database_cross_reference: VFB:FBbt_00040004
has OBO namespace: fly_anatomy.ontology
has related synonym: fibrous neuropil
id: FBbt:00040004

Axiom
annotated source: tract neuropil
annotated property: definition
annotated target: The part of the neuropil consisting largely of neuron projections without synapses.
database_cross_reference: FlyBase:FBrf0224194

synaptic neuropil
type: Class
subclass of: material anatomical entity
subclass of: Restriction
  on property: part of
  some values from: neuropil
definition: The part of the neuropil consisting largely of synapsing neuron projections.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-12T06:32:24Z
database_cross_reference: UBERON:6040005
database_cross_reference: VFB:FBbt_00040005
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040005

Axiom
annotated source: synaptic neuropil
annotated property: definition
annotated target: The part of the neuropil consisting largely of synapsing neuron projections.
database_cross_reference: FlyBase:FBrf0224194

synaptic neuropil subdomain
type: Class
subclass of: multi-cell-component structure
subclass of: synaptic neuropil
subclass of: Restriction
  on property: part of
  some values from: synaptic neuropil
definition: Synaptic neuropil region that is a subdivision of a synaptic neuropil domain.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-12T06:35:41Z
database_cross_reference: VFB:FBbt_00040006
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040006

Axiom
annotated source: synaptic neuropil subdomain
annotated property: definition
annotated target: Synaptic neuropil region that is a subdivision of a synaptic neuropil domain.
database_cross_reference: FlyBase:FBrf0224194

synaptic neuropil domain
type: Class
subclass of: multi-cell-component structure
subclass of: synaptic neuropil
subclass of: Restriction
  on property: part of
  some values from: synaptic neuropil
definition: Region of synaptic neuropil whose boundaries are largely discontinuities in the density of presynaptic terminals: high density in the synaptic neuropil domain, lower or zero density outside this region. These boundaries often correspond to a boundary with glial sheath, tract neuropil or cortex.
date: 2009-12-09T05:03:55Z
database_cross_reference: UBERON:6040007
database_cross_reference: VFB:FBbt_00040007
has OBO namespace: fly_anatomy.ontology
has related synonym: fibrous neuropil
has related synonym: synaptic neuropil
id: FBbt:00040007
in subset: cur
in subset: larval OF

Axiom
annotated source: synaptic neuropil domain
annotated property: definition
annotated target: Region of synaptic neuropil whose boundaries are largely discontinuities in the density of presynaptic terminals: high density in the synaptic neuropil domain, lower or zero density outside this region. These boundaries often correspond to a boundary with glial sheath, tract neuropil or cortex.
database_cross_reference: FlyBase:FBrf0155900
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0237252

synaptic neuropil layer
type: Class
subclass of: synaptic neuropil subdomain
definition: Laminar or concentric subdivision of a synaptic neuropil domain along its long axis delimited by a discontinuity in synaptic or fiber density.
date: 2009-12-09T05:03:55Z
database_cross_reference: VFB:FBbt_00040008
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040008

Axiom
annotated source: synaptic neuropil layer
annotated property: definition
annotated target: Laminar or concentric subdivision of a synaptic neuropil domain along its long axis delimited by a discontinuity in synaptic or fiber density.
database_cross_reference: FBC:KI
database_cross_reference: https://orcid.org/0000-0002-7073-9172

lobula layer 5
type: Class
subclass of: lobula layer
definition: Layer of the lobula that is fifth-most from the second optic-chiasm. It extends from the terminal arborizations of translobula plate neuron Tlp1 at the border of the fourth layer, to the extensive arborizations of lobula tangential neuron LT7, which defines layer 6.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-13T01:29:55Z
database_cross_reference: VFB:FBbt_00040016
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040016

Axiom
annotated source: lobula layer 5
annotated property: definition
annotated target: Layer of the lobula that is fifth-most from the second optic-chiasm. It extends from the terminal arborizations of translobula plate neuron Tlp1 at the border of the fourth layer, to the extensive arborizations of lobula tangential neuron LT7, which defines layer 6.
database_cross_reference: FlyBase:FBrf0049410

lobula layer 6
type: Class
subclass of: lobula layer
definition: Layer of the lobula that is the most distant from the second optic chiasm. It contains the extensive arborizations of lobula tangential neuron LT7.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-13T01:30:05Z
database_cross_reference: VFB:FBbt_00040017
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040017

Axiom
annotated source: lobula layer 6
annotated property: definition
annotated target: Layer of the lobula that is the most distant from the second optic chiasm. It contains the extensive arborizations of lobula tangential neuron LT7.
database_cross_reference: FlyBase:FBrf0049410

posterior ventrolateral protocerebrum
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: ventrolateral protocerebrum
definition: A glomerular, bilaterally paired synaptic neuropil domain lying in front of the posterior lateral protocerebrum (PLP), and above the wedge. The great commissure is at the boundary in the mid-level between the PLVP and PLP. It is contiguous with posterior lateral protocerebrum (PLP), which lies behind it. It houses many optic glomeruli formed by the terminals of neurons projecting from the optic lobe, primarily from the lobula. The boundary with the PLP, except at mid-level, is defined as the boundary between these glomeruli with different origins (lobula or lobula plate).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-13T04:18:03Z
database_cross_reference: VFB:FBbt_00040042
has exact synonym: PVLP
has exact synonym: posterior VLP
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040042
in subset: BrainName

Axiom
annotated source: posterior ventrolateral protocerebrum
annotated property: definition
annotated target: A glomerular, bilaterally paired synaptic neuropil domain lying in front of the posterior lateral protocerebrum (PLP), and above the wedge. The great commissure is at the boundary in the mid-level between the PLVP and PLP. It is contiguous with posterior lateral protocerebrum (PLP), which lies behind it. It houses many optic glomeruli formed by the terminals of neurons projecting from the optic lobe, primarily from the lobula. The boundary with the PLP, except at mid-level, is defined as the boundary between these glomeruli with different origins (lobula or lobula plate).
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00040042

Axiom
annotated source: posterior ventrolateral protocerebrum
annotated property: hasExactSynonym
annotated target: PVLP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

posterior lateral protocerebrum
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: ventrolateral neuropils
definition: A bilaterally paired synaptic neuropil domain of the adult that contains many glomeruli and is located behind the posterior ventrolateral protocerebrum (PVLP) and above the wedge. The mid-level of the posterior lateral protocerebrum (PLP) is separated from the PVLP by the great commissure, but above and below this the two neuropils are contiguous. The PLP houses many optic glomeruli formed by the terminals of neurons projecting from the optic lobe, primarily from the lobula plate. The boundary with the PVLP is defined by the boundary between these glomeruli that have different origins (lobula or lobula plate).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-13T04:23:57Z
database_cross_reference: VFB:FBbt_00040044
has exact synonym: PLP
has exact synonym: posteriolateral protocerebrum
has exact synonym: posterior-lateral protocerebrum
has exact synonym: posteriorlateral protocerebrum
has narrow synonym: CVLP
has OBO namespace: fly_anatomy.ontology
has related synonym: SPP
has related synonym: plpr
id: FBbt:00040044
in subset: BrainName
comment: The PLP corresponds to almost all of the plpr of Otsuna and Ito (2006) and to the caudal ventrolateral protocerebrum (CVLP) and lateral part of the superpeduncular protocerebrum (SPP) of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: posterior lateral protocerebrum
annotated property: definition
annotated target: A bilaterally paired synaptic neuropil domain of the adult that contains many glomeruli and is located behind the posterior ventrolateral protocerebrum (PVLP) and above the wedge. The mid-level of the posterior lateral protocerebrum (PLP) is separated from the PVLP by the great commissure, but above and below this the two neuropils are contiguous. The PLP houses many optic glomeruli formed by the terminals of neurons projecting from the optic lobe, primarily from the lobula plate. The boundary with the PVLP is defined by the boundary between these glomeruli that have different origins (lobula or lobula plate).
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00040044

Axiom
annotated source: posterior lateral protocerebrum
annotated property: hasExactSynonym
annotated target: PLP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: posterior lateral protocerebrum
annotated property: hasExactSynonym
annotated target: posteriorlateral protocerebrum
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: posterior lateral protocerebrum
annotated property: hasNarrowSynonym
annotated target: CVLP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: posterior lateral protocerebrum
annotated property: hasRelatedSynonym
annotated target: SPP
database_cross_reference: FlyBase:FBrf0212704

Axiom
annotated source: posterior lateral protocerebrum
annotated property: hasRelatedSynonym
annotated target: plpr
database_cross_reference: FlyBase:FBrf0193607

synaptic neuropil segment
type: Class
subclass of: synaptic neuropil subdomain
definition: Laminar or radial subdivision of a synaptic neuropil domain along its short axis delimited by a discontinuity in synaptic or fiber density.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-14T01:35:18Z
database_cross_reference: VFB:FBbt_00040069
has OBO namespace: fly_anatomy.ontology
id: FBbt:00040069

Axiom
annotated source: synaptic neuropil segment
annotated property: definition
annotated target: Laminar or radial subdivision of a synaptic neuropil domain along its short axis delimited by a discontinuity in synaptic or fiber density.
database_cross_reference: FBC:KI
database_cross_reference: https://orcid.org/0000-0002-7073-9172

posterior slope
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: ventromedial neuropils
definition: Synaptic neuropil domain of the adult brain that is the inferior (ventral) part of the posterior cerebral ganglion, covering the area between the inferior bridge and the gnathal ganglion with its superior part lying behind the ventral complex. It contains extensive arborizations of ascending and descending neurons. Its superior boundary is the level above which such arborizations do not occur. It also contains the terminals of axons from the ocellar ganglia, projecting via the ocellar nerves.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-02-24T03:41:00Z
database_cross_reference: VFB:FBbt_00040072
has exact synonym: PS
has OBO namespace: fly_anatomy.ontology
has related synonym: CMP
id: FBbt:00040072
in subset: BrainName
comment: The ventral complex corresponds to the caudal medial protocerebrum (CMP) and possibly includes part of the ventromedial protocerebrum (VMP) of Chiang et al. (2011) (Ito et al., 2014).

Axiom
annotated source: posterior slope
annotated property: definition
annotated target: Synaptic neuropil domain of the adult brain that is the inferior (ventral) part of the posterior cerebral ganglion, covering the area between the inferior bridge and the gnathal ganglion with its superior part lying behind the ventral complex. It contains extensive arborizations of ascending and descending neurons. Its superior boundary is the level above which such arborizations do not occur. It also contains the terminals of axons from the ocellar ganglia, projecting via the ocellar nerves.
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00040072

Axiom
annotated source: posterior slope
annotated property: hasExactSynonym
annotated target: PS
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: posterior slope
annotated property: hasRelatedSynonym
annotated target: CMP
database_cross_reference: FlyBase:FBrf0212704

synaptic neuropil block
type: Class
subclass of: disconnected anatomical group
subclass of: synaptic neuropil
subclass of: Restriction
  on property: part of
  some values from: synaptic neuropil
definition: A closely associated group of synaptic neuropil domains.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2009-08-12T04:30:28Z
database_cross_reference: UBERON:6041000
database_cross_reference: VFB:FBbt_00041000
has exact synonym: level 1 neuropil
has OBO namespace: fly_anatomy.ontology
id: FBbt:00041000

Axiom
annotated source: synaptic neuropil block
annotated property: definition
annotated target: A closely associated group of synaptic neuropil domains.
database_cross_reference: FBC:KI
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: synaptic neuropil block
annotated property: hasExactSynonym
annotated target: level 1 neuropil
database_cross_reference: FlyBase:FBrf0224194

plexiform medulla
type: Class
subclass of: medulla layer
definition: Region of the medulla excluding the medulla dorsal rim area.
database_cross_reference: VFB:FBbt_00045001
has exact synonym: MEP
has exact synonym: PLME
has exact synonym: medulla proper
has OBO namespace: fly_anatomy.ontology
id: FBbt:00045001
in subset: BrainName

Axiom
annotated source: plexiform medulla
annotated property: definition
annotated target: Region of the medulla excluding the medulla dorsal rim area.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: plexiform medulla
annotated property: hasExactSynonym
annotated target: PLME
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

lobula complex
type: Class
subclass of: synaptic neuropil block
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
definition: A synaptic neuropil block in the adult brain consisting of the two medial-most synaptic neuropil domains of the optic lobe: the lobula and the lobula plate.
database_cross_reference: VFB:FBbt_00045004
has exact synonym: LOX
has OBO namespace: fly_anatomy.ontology
id: FBbt:00045004
in subset: BrainName

Axiom
annotated source: lobula complex
annotated property: definition
annotated target: A synaptic neuropil block in the adult brain consisting of the two medial-most synaptic neuropil domains of the optic lobe: the lobula and the lobula plate.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: lobula complex
annotated property: hasExactSynonym
annotated target: LOX
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

ventrolateral neuropils
type: Class
subclass of: synaptic neuropil block
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
definition: Synaptic neuropil block in the adult brain located along the ventrolateral side of the adult central brain.
database_cross_reference: VFB:FBbt_00045021
has exact synonym: VLNP
has OBO namespace: fly_anatomy.ontology
id: FBbt:00045021
in subset: BrainName
comment: Despite the name, intended as a singular noun as in "The United States".

Axiom
annotated source: ventrolateral neuropils
annotated property: definition
annotated target: Synaptic neuropil block in the adult brain located along the ventrolateral side of the adult central brain.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: ventrolateral neuropils
annotated property: hasExactSynonym
annotated target: VLNP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

wedge
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: ventrolateral neuropils
definition: An aglomerular, bilaterally paired synaptic neuropil domain that is the inferior-most domain of the ventrolateral neuropils, lying between the anterior and posterior ventrolateral protocerebrum (AVLP and PVLP) and posteriorlateral protocerebrum (PLP), and the saddle and gnathal ganglion. The wedge is lateral to the inferior fiber system and vest. It receives synaptic input from the saddle and the antennal mechanosensory and motor center (AMMC) within it. This includes direct sensory input from antennal mechanosensory neurons that also innervate the AMMC.
database_cross_reference: VFB:FBbt_00045027
has exact synonym: IVLP
has exact synonym: VLCi
has exact synonym: WED
has exact synonym: inferior VLP
has exact synonym: inferior ventrolateral protocerebrum
has OBO namespace: fly_anatomy.ontology
has related synonym: CVLP
has related synonym: caudal VLP
has related synonym: plpr
has related synonym: vlpr
id: FBbt:00045027
in subset: BrainName
comment: The anterior wedge corresponds to the inferior part of the vlpr of Otsuna and Ito (2006); the posterior wedge corresponds to part of the plpr (Ito et al., 2014).

Axiom
annotated source: wedge
annotated property: definition
annotated target: An aglomerular, bilaterally paired synaptic neuropil domain that is the inferior-most domain of the ventrolateral neuropils, lying between the anterior and posterior ventrolateral protocerebrum (AVLP and PVLP) and posteriorlateral protocerebrum (PLP), and the saddle and gnathal ganglion. The wedge is lateral to the inferior fiber system and vest. It receives synaptic input from the saddle and the antennal mechanosensory and motor center (AMMC) within it. This includes direct sensory input from antennal mechanosensory neurons that also innervate the AMMC.
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00045027

Axiom
annotated source: wedge
annotated property: hasExactSynonym
annotated target: IVLP
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: wedge
annotated property: hasExactSynonym
annotated target: VLCi
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: wedge
annotated property: hasExactSynonym
annotated target: WED
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: wedge
annotated property: hasExactSynonym
annotated target: inferior VLP
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: wedge
annotated property: hasExactSynonym
annotated target: inferior ventrolateral protocerebrum
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: wedge
annotated property: hasRelatedSynonym
annotated target: plpr
database_cross_reference: FlyBase:FBrf0193607

Axiom
annotated source: wedge
annotated property: hasRelatedSynonym
annotated target: vlpr
database_cross_reference: FlyBase:FBrf0193607

superior neuropils
type: Class
subclass of: synaptic neuropil block
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
definition: A block of synaptic neuropil domains in the adult brain arranged in a layer covering the superior (dorsal) surface of the brain. In encompasses the superior intermediate, superior lateral and superior medial protocerebrum.
database_cross_reference: VFB:FBbt_00045030
has exact synonym: SNP
has exact synonym: superior protocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00045030
in subset: BrainName
comment: Despite the name, intended as a singular noun as in 'The United States'.

Axiom
annotated source: superior neuropils
annotated property: definition
annotated target: A block of synaptic neuropil domains in the adult brain arranged in a layer covering the superior (dorsal) surface of the brain. In encompasses the superior intermediate, superior lateral and superior medial protocerebrum.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: superior neuropils
annotated property: hasExactSynonym
annotated target: SNP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: superior neuropils
annotated property: hasExactSynonym
annotated target: superior protocerebrum
database_cross_reference: FlyBase:FBrf0224194

inferior posterior slope
type: Class
subclass of: synaptic neuropil subdomain
subclass of: Restriction
  on property: part of
  some values from: posterior slope
definition: Inferior (ventral) part of the posterior slope. It flanks both sides of the esophagus, and is posterior and medial to the wedge. Below the plane of the inferior VLP commissure and the posterior optic commissure.
database_cross_reference: VFB:FBbt_00045046
has exact synonym: IPS
has exact synonym: VMCpov
has exact synonym: ventral postcommissural VMC
has OBO namespace: fly_anatomy.ontology
has related synonym: psl
id: FBbt:00045046
in subset: BrainName
comment: The IPS corresponds to part of the psl of Otsuna and Ito (2006) and to the ventral postcommissural ventromedial cerebrum (Ito et al., 2014).

Axiom
annotated source: inferior posterior slope
annotated property: definition
annotated target: Inferior (ventral) part of the posterior slope. It flanks both sides of the esophagus, and is posterior and medial to the wedge. Below the plane of the inferior VLP commissure and the posterior optic commissure.
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: inferior posterior slope
annotated property: hasExactSynonym
annotated target: IPS
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: inferior posterior slope
annotated property: hasExactSynonym
annotated target: VMCpov
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: inferior posterior slope
annotated property: hasExactSynonym
annotated target: ventral postcommissural VMC
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: inferior posterior slope
annotated property: hasRelatedSynonym
annotated target: psl
database_cross_reference: FlyBase:FBrf0193607

adult periesophageal neuropils
type: Class
subclass of: synaptic neuropil block
subclass of: Restriction
  on property: part of
  some values from: adult cerebrum
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval periesophageal neuropils
definition: Group of synaptic neuropil domains in the adult brain located between the antennal lobe/ventromedial neuropils and above the gnathal ganglia. In addition, it includes one synaptic domain that is part of the ventral cerebral ganglion-the prow.
database_cross_reference: VFB:FBbt_00045047
has exact synonym: PENP
has OBO namespace: fly_anatomy.ontology
id: FBbt:00045047
in subset: BrainName
comment: Despite the name, it is intended as a singular noun as in "The United States".

Axiom
annotated source: adult periesophageal neuropils
annotated property: definition
annotated target: Group of synaptic neuropil domains in the adult brain located between the antennal lobe/ventromedial neuropils and above the gnathal ganglia. In addition, it includes one synaptic domain that is part of the ventral cerebral ganglion-the prow.
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult periesophageal neuropils
annotated property: hasExactSynonym
annotated target: PENP
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

saddle
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: adult periesophageal neuropils
subclass of: Restriction
  on property: part of
  some values from: adult subesophageal zone
definition: Synaptic neuropil domain covering the dorsal and posterior surface of the adult gnathal ganglia. It contains the antennal mechanosensory and motor center (AMMC).
database_cross_reference: VFB:FBbt_00045048
has exact synonym: SAD
has narrow synonym: PENPl
has narrow synonym: PENPvm
has narrow synonym: lateral perioesophageal neuropils
has narrow synonym: ventromedial perioesophageal neuropils
has OBO namespace: fly_anatomy.ontology
has related synonym: AMMC
id: FBbt:00045048
in subset: BrainName
comment: The saddle corresponds to the antennal mechanosensory and motor center (AMMC) of Chiang et al. (2011) and to the lateral and ventromedial periesophageal neuropils (Ito et al., 2014).

Axiom
annotated source: saddle
annotated property: definition
annotated target: Synaptic neuropil domain covering the dorsal and posterior surface of the adult gnathal ganglia. It contains the antennal mechanosensory and motor center (AMMC).
database_cross_reference: FlyBase:FBrf0212704
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: VFB_vol:00045048

Axiom
annotated source: saddle
annotated property: hasExactSynonym
annotated target: SAD
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: saddle
annotated property: hasNarrowSynonym
annotated target: PENPl
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: saddle
annotated property: hasNarrowSynonym
annotated target: PENPvm
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: saddle
annotated property: hasNarrowSynonym
annotated target: lateral perioesophageal neuropils
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: saddle
annotated property: hasNarrowSynonym
annotated target: ventromedial perioesophageal neuropils
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: saddle
annotated property: hasRelatedSynonym
annotated target: AMMC
database_cross_reference: FlyBase:FBrf0212704

adult neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: neuron
subclass of: Restriction
  on property: part of
  some values from: adult nervous system
definition: A neuron that is part of the adult nervous system. These can be born during the postembryonic phase of neurogenesis (Lacin and Truman, 2016) or they can develop from larval neurons during the pupal stage (Veverytsa and Allan, 2013).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-02-19T16:52:12Z
database_cross_reference: VFB:FBbt_00047095
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047095

Axiom
annotated source: adult neuron
annotated property: definition
annotated target: A neuron that is part of the adult nervous system. These can be born during the postembryonic phase of neurogenesis (Lacin and Truman, 2016) or they can develop from larval neurons during the pupal stage (Veverytsa and Allan, 2013).
database_cross_reference: FlyBase:FBrf0221900
database_cross_reference: FlyBase:FBrf0231327

secondary neuron
type: Class
subclass of: neuron
definition: Neuron that is born during the second round of neurogenesis, which commences during the larval stage, after a period of neuroblast quiescence (Lacin and Truman, 2016).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-02-20T10:10:37Z
database_cross_reference: VFB:FBbt_00047096
has exact synonym: adult-specific neuron
has exact synonym: postembryonic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047096

Axiom
annotated source: secondary neuron
annotated property: definition
annotated target: Neuron that is born during the second round of neurogenesis, which commences during the larval stage, after a period of neuroblast quiescence (Lacin and Truman, 2016).
database_cross_reference: FlyBase:FBrf0231327

Axiom
annotated source: secondary neuron
annotated property: hasExactSynonym
annotated target: adult-specific neuron
database_cross_reference: FlyBase:FBrf0231327

Axiom
annotated source: secondary neuron
annotated property: hasExactSynonym
annotated target: postembryonic neuron
database_cross_reference: FlyBase:FBrf0231327

gut
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: alimentary canal
definition: Structure consisting of a simple epithelium surrounded by visceral muscles, nerves and tracheae. The gut is divided into foregut, midgut and hindgut regions, based on developmental origin.
contributor: https://orcid.org/0000-0002-1373-1705
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047143

Axiom
annotated source: gut
annotated property: definition
annotated target: Structure consisting of a simple epithelium surrounded by visceral muscles, nerves and tracheae. The gut is divided into foregut, midgut and hindgut regions, based on developmental origin.
database_cross_reference: FlyBase:FBrf0223413

imaginal tissue
type: Class
subclass of: developing material anatomical entity
definition: Any group of similar imaginal cells, such as an imaginal disc, imaginal ring or imaginal island, or a precursor tissue that forms one of them. These tissues develop separately from other embryonic and larval tissues and they generate adult structures during metamorphosis.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-08-15T09:31:08Z
has exact synonym: imaginal structure
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047552
in subset: expressionslim flybase ribbon

Axiom
annotated source: imaginal tissue
annotated property: definition
annotated target: Any group of similar imaginal cells, such as an imaginal disc, imaginal ring or imaginal island, or a precursor tissue that forms one of them. These tissues develop separately from other embryonic and larval tissues and they generate adult structures during metamorphosis.
database_cross_reference: FlyBase:FBrf0064789

Axiom
annotated source: imaginal tissue
annotated property: hasExactSynonym
annotated target: imaginal structure
database_cross_reference: FlyBase:FBrf0053815

larval visual local interneuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: larval optic neuropil
subclass of: supraesophageal ganglion neuron
subclass of: larval interneuron
subclass of: Restriction
  on property: part of
  some values from: larval brain
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of larval brain
subclass of: Restriction
  on property: synapses restricted to region
  some values from: larval optic neuropil
definition: Larval neuron that does not extend neurites beyond the optic neuropil.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-09-18T11:03:37Z
database_cross_reference: VFB:FBbt_00047733
has exact synonym: VLN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047733

Axiom
annotated source: larval visual local interneuron
annotated property: definition
annotated target: Larval neuron that does not extend neurites beyond the optic neuropil.
database_cross_reference: FlyBase:FBrf0237760

Axiom
annotated source: larval visual local interneuron
annotated property: hasExactSynonym
annotated target: VLN
database_cross_reference: FlyBase:FBrf0237760

larval visual projection interneuron
type: Class
equivalent class: Class
  intersection of: visual projection neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: supraesophageal ganglion neuron
subclass of: visual projection neuron
subclass of: larval interneuron
subclass of: Restriction
  on property: part of
  some values from: larval brain
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of larval brain
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: larval optic neuropil
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: larval central brain
definition: Larval neuron that relays signals from the optic neuropil to higher brain areas. Many of these receive input from Rh5 photoreceptor cells.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-09-18T11:12:05Z
database_cross_reference: VFB:FBbt_00047734
has exact synonym: larval VPN
has exact synonym: larval visual PN
has exact synonym: larval visual projection neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047734

Axiom
annotated source: larval visual projection interneuron
annotated property: definition
annotated target: Larval neuron that relays signals from the optic neuropil to higher brain areas. Many of these receive input from Rh5 photoreceptor cells.
database_cross_reference: FlyBase:FBrf0237760

Axiom
annotated source: larval visual projection interneuron
annotated property: hasExactSynonym
annotated target: larval VPN
database_cross_reference: FlyBase:FBrf0237760

Axiom
annotated source: larval visual projection interneuron
annotated property: hasExactSynonym
annotated target: larval visual PN
database_cross_reference: FlyBase:FBrf0236359

Axiom
annotated source: larval visual projection interneuron
annotated property: hasExactSynonym
annotated target: larval visual projection neuron
database_cross_reference: FlyBase:FBrf0236359

visual system
type: Class
equivalent class: Class
  intersection of: non-connected functional system
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050953
subclass of: sensory system
subclass of: Restriction
  on property: capable of
  some values from: GO_0050953
definition: An anatomical system consisting of all of the anatomical entities that function in some part of the sensory perception of light.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-09-18T13:08:28Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047735

Axiom
annotated source: visual system
annotated property: definition
annotated target: An anatomical system consisting of all of the anatomical entities that function in some part of the sensory perception of light.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

visual system neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of part of
    some values from: GO_0050953
subclass of: sensory system neuron
subclass of: Restriction
  on property: part of
  some values from: visual system
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0050953
definition: Any neuron (FBbt:00005106) that capable of part of some sensory perception of light stimulus (GO:0050953).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-09-18T13:09:24Z
database_cross_reference: VFB:FBbt_00047736
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047736

Axiom
annotated source: visual system neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that capable of part of some sensory perception of light stimulus (GO:0050953).
database_cross_reference: https://orcid.org/0000-0002-1373-1705

ensheathing glial cell
type: Class
subclass of: neuropil glial cell
definition: Polarized glial cell with a flattened cell body that forms a sheath around the synaptic and tract neuropil regions (Hartenstein, 2011; Pogodalla et al., 2021). They may serve a homologous function to the wrapping glia, which ensheath the peripheral nerves (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-17T09:16:04Z
database_cross_reference: VFB:FBbt_00047836
has exact synonym: EG
has exact synonym: ensheathing neuropil associated glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047836

Axiom
annotated source: ensheathing glial cell
annotated property: definition
annotated target: Polarized glial cell with a flattened cell body that forms a sheath around the synaptic and tract neuropil regions (Hartenstein, 2011; Pogodalla et al., 2021). They may serve a homologous function to the wrapping glia, which ensheath the peripheral nerves (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0234767
database_cross_reference: FlyBase:FBrf0239943
database_cross_reference: FlyBase:FBrf0251788

Axiom
annotated source: ensheathing glial cell
annotated property: hasExactSynonym
annotated target: EG
database_cross_reference: FlyBase:FBrf0229106

embryonic/larval ensheathing glial cell
type: Class
equivalent class: Class
  intersection of: ensheathing glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: ensheathing glial cell
subclass of: larval neuropil glial cell
definition: Ensheathing glial cell of the larva. There are approximately 112 of these cells in the third instar central nervous system (Pogodalla et al., 2021). Some of these cells are polyploid, but others can undergo cell division during the pupal stage to generate adult glia (Kato et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-17T09:44:55Z
database_cross_reference: VFB:FBbt_00047837
has exact synonym: L-EG
has exact synonym: embryonic/larval ensheathing neuropil associated glial cell
has exact synonym: larval pEG
has exact synonym: larval primary ensheathing glia
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047837

Axiom
annotated source: embryonic/larval ensheathing glial cell
annotated property: definition
annotated target: Ensheathing glial cell of the larva. There are approximately 112 of these cells in the third instar central nervous system (Pogodalla et al., 2021). Some of these cells are polyploid, but others can undergo cell division during the pupal stage to generate adult glia (Kato et al., 2020).
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0229106
database_cross_reference: FlyBase:FBrf0239943
database_cross_reference: FlyBase:FBrf0251788

Axiom
annotated source: embryonic/larval ensheathing glial cell
annotated property: hasExactSynonym
annotated target: L-EG
database_cross_reference: FlyBase:FBrf0245107

Axiom
annotated source: embryonic/larval ensheathing glial cell
annotated property: hasExactSynonym
annotated target: larval pEG
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: embryonic/larval ensheathing glial cell
annotated property: hasExactSynonym
annotated target: larval primary ensheathing glia
database_cross_reference: FlyBase:FBrf0229106

embryonic/larval astrocyte-like glial cell
type: Class
equivalent class: Class
  intersection of: astrocyte-like glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuropil glial cell
subclass of: embryonic/larval lateral glial cell
subclass of: astrocyte-like glial cell
definition: Astrocyte-like glial cell of the embryonic/larval central nervous system. There are approximately 15 of these cells in each brain hemisphere (Omoto et al., 2015) and 6 per ventral nerve cord hemineuromere (Peco et al., 2016) throughout larval development. They appear to endoreplicate and increase in size, then die during metamorphosis (Omoto et al., 2015; Kato et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-17T10:46:27Z
database_cross_reference: VFB:FBbt_00047840
has exact synonym: embryonic/larval astrocyte
has exact synonym: embryonic/larval astrocyte-like neuropil associated glial cell
has exact synonym: embryonic/larval astrocytic glia
has exact synonym: embryonic/larval dendritic neuropil associated glial cell
has exact synonym: embryonic/larval reticular neuropil associated glial cell
has exact synonym: embryonic/larval reticular neuropil-associated glial cell
has exact synonym: pALG
has exact synonym: primary astrocyte-like glia
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047840

Axiom
annotated source: embryonic/larval astrocyte-like glial cell
annotated property: definition
annotated target: Astrocyte-like glial cell of the embryonic/larval central nervous system. There are approximately 15 of these cells in each brain hemisphere (Omoto et al., 2015) and 6 per ventral nerve cord hemineuromere (Peco et al., 2016) throughout larval development. They appear to endoreplicate and increase in size, then die during metamorphosis (Omoto et al., 2015; Kato et al., 2020).
database_cross_reference: FlyBase:FBrf0206543
database_cross_reference: FlyBase:FBrf0225669
database_cross_reference: FlyBase:FBrf0229106
database_cross_reference: FlyBase:FBrf0231858
database_cross_reference: FlyBase:FBrf0245107

Axiom
annotated source: embryonic/larval astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: embryonic/larval astrocyte
database_cross_reference: FlyBase:FBrf0225669

Axiom
annotated source: embryonic/larval astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: embryonic/larval astrocyte-like neuropil associated glial cell
database_cross_reference: FlyBase:FBrf0206543

Axiom
annotated source: embryonic/larval astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: embryonic/larval astrocytic glia
database_cross_reference: FlyBase:FBrf0207750

Axiom
annotated source: embryonic/larval astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: embryonic/larval reticular neuropil associated glial cell
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: embryonic/larval astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: embryonic/larval reticular neuropil-associated glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: embryonic/larval astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: pALG
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: embryonic/larval astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: primary astrocyte-like glia
database_cross_reference: FlyBase:FBrf0229106

adult astrocyte-like glial cell
type: Class
equivalent class: Class
  intersection of: astrocyte-like glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult neuropil glial cell
subclass of: astrocyte-like glial cell
definition: Neuropil associated glial cell of the adult central nervous system that has a dendritic morphology and elaborates inside the associated synaptic neuropil (Awasaki et al., 2008). Their nuclei are found at synaptic neuropil surfaces and they extend branched filiform or lamelliform processes that pervade the neuropil (Hartenstein, 2011).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-17T10:51:10Z
database_cross_reference: VFB:FBbt_00047841
has exact synonym: adult ALG
has exact synonym: adult astrocyte
has exact synonym: adult astrocyte-like neuropil associated glial cell
has exact synonym: adult astrocytic glia
has exact synonym: adult dendritic neuropil associated glial cell
has exact synonym: adult reticular neuropil associated glial cell
has exact synonym: adult reticular neuropil-associated glial cell
has narrow synonym: sALG
has narrow synonym: secondary astrocyte-like glia
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047841

Axiom
annotated source: adult astrocyte-like glial cell
annotated property: definition
annotated target: Neuropil associated glial cell of the adult central nervous system that has a dendritic morphology and elaborates inside the associated synaptic neuropil (Awasaki et al., 2008). Their nuclei are found at synaptic neuropil surfaces and they extend branched filiform or lamelliform processes that pervade the neuropil (Hartenstein, 2011).
database_cross_reference: FlyBase:FBrf0206543
database_cross_reference: FlyBase:FBrf0207750
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0225669

Axiom
annotated source: adult astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: adult ALG
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: adult astrocyte
database_cross_reference: FlyBase:FBrf0225669

Axiom
annotated source: adult astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: adult astrocyte-like neuropil associated glial cell
database_cross_reference: FlyBase:FBrf0206543

Axiom
annotated source: adult astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: adult astrocytic glia
database_cross_reference: FlyBase:FBrf0207750

Axiom
annotated source: adult astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: adult reticular neuropil-associated glial cell
database_cross_reference: FlyBase:FBrf0214261

Axiom
annotated source: adult astrocyte-like glial cell
annotated property: hasNarrowSynonym
annotated target: sALG
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: adult astrocyte-like glial cell
annotated property: hasNarrowSynonym
annotated target: secondary astrocyte-like glia
database_cross_reference: FlyBase:FBrf0229106

larval neuropil glial cell
type: Class
equivalent class: Class
  intersection of: neuropil glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval glial cell
subclass of: neuropil glial cell
subclass of: Restriction
  on property: part of
  some values from: larval neuropil glial sheath
definition: Any neuropil glial cell of the larva.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-22T09:49:57Z
database_cross_reference: VFB:FBbt_00047856
has exact synonym: larval neuropil associated glial cell
has exact synonym: larval pNPG
has exact synonym: larval primary neuropil glia
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047856

Axiom
annotated source: larval neuropil glial cell
annotated property: definition
annotated target: Any neuropil glial cell of the larva.
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: larval neuropil glial cell
annotated property: hasExactSynonym
annotated target: larval pNPG
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: larval neuropil glial cell
annotated property: hasExactSynonym
annotated target: larval primary neuropil glia
database_cross_reference: FlyBase:FBrf0229106

larval brain neuropil glial cell
type: Class
equivalent class: Class
  intersection of: neuropil glial cell
  intersection of: Restriction
    on property: part of
    some values from: larval brain
subclass of: larval neuropil glial cell
subclass of: Restriction
  on property: part of
  some values from: larval brain
definition: Any neuropil glial cell (FBbt:00001303) that is part of some larval brain (FBbt:00001920).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-22T09:55:07Z
database_cross_reference: VFB:FBbt_00047857
has exact synonym: larval pNPG of brain
has exact synonym: primary neuropil glia of brain
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047857

Axiom
annotated source: larval brain neuropil glial cell
annotated property: definition
annotated target: Any neuropil glial cell (FBbt:00001303) that is part of some larval brain (FBbt:00001920).
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: larval brain neuropil glial cell
annotated property: hasExactSynonym
annotated target: larval pNPG of brain
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: larval brain neuropil glial cell
annotated property: hasExactSynonym
annotated target: primary neuropil glia of brain
database_cross_reference: FlyBase:FBrf0229106

adult brain neuropil glial cell
type: Class
equivalent class: Class
  intersection of: adult neuropil glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult brain
subclass of: adult neuropil glial cell
subclass of: Restriction
  on property: part of
  some values from: adult brain
definition: Glial cell that is part of the glial sheath surrounding the neuropil of the adult brain.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-22T09:55:57Z
database_cross_reference: VFB:FBbt_00047859
has narrow synonym: sNPG of brain
has narrow synonym: secondary neuropil glia of brain
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047859

Axiom
annotated source: adult brain neuropil glial cell
annotated property: definition
annotated target: Glial cell that is part of the glial sheath surrounding the neuropil of the adult brain.
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: adult brain neuropil glial cell
annotated property: hasNarrowSynonym
annotated target: sNPG of brain
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: adult brain neuropil glial cell
annotated property: hasNarrowSynonym
annotated target: secondary neuropil glia of brain
database_cross_reference: FlyBase:FBrf0229106

embryonic/larval lateral glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: larval nervous system
  intersection of: Restriction
    on property: expresses
    some values from: FBgn0011701
subclass of: larval glial cell
subclass of: Restriction
  on property: expresses
  some values from: FBgn0011701
definition: Any glial cell of the embryo or larva that derives from the neurogenic region of the ectoderm. Their identity is established by the expression of the gene glial cells missing (gcm), which results in expression of reversed polarity (repo), often used as a marker for lateral glia (Jacobs, 2000). This includes perineurial and subperineurial glia of the central and peripheral nervous systems, cell body (cortex) glia, wrapping glia and some of the neuropil associated glia (Beckervordersandforth et al., 2008). There are around 25 of these per abdominal hemisegment in a stage 16 embryo (Beckervordersandforth et al., 2008).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-22T12:36:01Z
database_cross_reference: VFB:FBbt_00047861
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047861

Axiom
annotated source: embryonic/larval lateral glial cell
annotated property: definition
annotated target: Any glial cell of the embryo or larva that derives from the neurogenic region of the ectoderm. Their identity is established by the expression of the gene glial cells missing (gcm), which results in expression of reversed polarity (repo), often used as a marker for lateral glia (Jacobs, 2000). This includes perineurial and subperineurial glia of the central and peripheral nervous systems, cell body (cortex) glia, wrapping glia and some of the neuropil associated glia (Beckervordersandforth et al., 2008). There are around 25 of these per abdominal hemisegment in a stage 16 embryo (Beckervordersandforth et al., 2008).
database_cross_reference: FlyBase:FBrf0128507
database_cross_reference: FlyBase:FBrf0205499

precursor of adult central brain neuropil glia
type: Class
subclass of: anterior ectoderm derivative
subclass of: somatic cell
subclass of: Restriction
  on property: part of
  some values from: brain
subclass of: Restriction
  on property: develops from
  some values from: type II neuroblast
definition: Precursor of neuropil associated glia of the adult central brain. It arises from a type II neuroblast in the central brain during larval development. Different neuroblasts generally contribute to glia of different adult brain regions. These precursors clonally expand during metamorphosis, spread out across the neuropil surfaces and mature into adult glia.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-24T14:02:49Z
database_cross_reference: VFB:FBbt_00047884
has exact synonym: sNPG precursor of central brain
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047884
comment: Some of these cells migrate to the optic lobe, but optic lobe-born glia do not migrate to the central brain (Omoto et al., 2015).

Axiom
annotated source: precursor of adult central brain neuropil glia
annotated property: definition
annotated target: Precursor of neuropil associated glia of the adult central brain. It arises from a type II neuroblast in the central brain during larval development. Different neuroblasts generally contribute to glia of different adult brain regions. These precursors clonally expand during metamorphosis, spread out across the neuropil surfaces and mature into adult glia.
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: precursor of adult central brain neuropil glia
annotated property: hasExactSynonym
annotated target: sNPG precursor of central brain
database_cross_reference: FlyBase:FBrf0229106

adult central brain astrocyte-like glial cell
type: Class
equivalent class: Class
  intersection of: astrocyte-like glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult central brain
subclass of: anterior ectoderm derivative
subclass of: adult astrocyte-like glial cell
subclass of: adult brain neuropil glial cell
subclass of: Restriction
  on property: part of
  some values from: adult central brain
subclass of: Restriction
  on property: develops from
  some values from: precursor of adult central brain neuropil glia
definition: Astrocyte-like glial cell of the adult central brain. These cells have their nuclei at synaptic neuropil surfaces throughout the central brain (not just adjacent to the cell body rind) and they extend processes into the synaptic and/or tract neuropil (Kremer et al., 2017). They have variable size and morphology and one cell may project into more than one neuropil region, but cells tend to cover non-overlapping areas (Kremer et al., 2017). Reticular glial cell processes in the synaptic neuropil of the central brain tend to be more dense in neuropil regions where synaptic terminals of neurons are less dense (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-24T14:32:43Z
database_cross_reference: VFB:FBbt_00047885
has exact synonym: adult central brain astrocyte
has exact synonym: adult central brain reticular glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047885

Axiom
annotated source: adult central brain astrocyte-like glial cell
annotated property: definition
annotated target: Astrocyte-like glial cell of the adult central brain. These cells have their nuclei at synaptic neuropil surfaces throughout the central brain (not just adjacent to the cell body rind) and they extend processes into the synaptic and/or tract neuropil (Kremer et al., 2017). They have variable size and morphology and one cell may project into more than one neuropil region, but cells tend to cover non-overlapping areas (Kremer et al., 2017). Reticular glial cell processes in the synaptic neuropil of the central brain tend to be more dense in neuropil regions where synaptic terminals of neurons are less dense (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0229106
database_cross_reference: FlyBase:FBrf0234767

adult central brain ensheathing glial cell
type: Class
equivalent class: Class
  intersection of: ensheathing glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult central brain
subclass of: anterior ectoderm derivative
subclass of: adult brain neuropil glial cell
subclass of: adult ensheathing glial cell
subclass of: Restriction
  on property: part of
  some values from: adult central brain
subclass of: Restriction
  on property: develops from
  some values from: precursor of adult central brain neuropil glia
definition: Any ensheathing glial cell (FBbt:00047836) that is part of some adult central brain (FBbt:00047887).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-24T14:33:00Z
database_cross_reference: VFB:FBbt_00047886
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047886

Axiom
annotated source: adult central brain ensheathing glial cell
annotated property: definition
annotated target: Any ensheathing glial cell (FBbt:00047836) that is part of some adult central brain (FBbt:00047887).
database_cross_reference: FlyBase:FBrf0229106

adult central brain
type: Class
subclass of: central brain
subclass of: Restriction
  on property: part of
  some values from: adult brain
definition: Adult brain excluding the optic lobes. This consists of the cerebrum and the gnathal ganglion.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-24T14:35:45Z
database_cross_reference: VFB:FBbt_00047887
has exact synonym: midbrain
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047887

Axiom
annotated source: adult central brain
annotated property: definition
annotated target: Adult brain excluding the optic lobes. This consists of the cerebrum and the gnathal ganglion.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult central brain
annotated property: hasExactSynonym
annotated target: midbrain
database_cross_reference: FlyBase:FBrf0224194

central brain
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part of
  some values from: brain
definition: Brain excluding the optic lobes.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-24T15:11:55Z
database_cross_reference: VFB:FBbt_00047888
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047888

Axiom
annotated source: central brain
annotated property: definition
annotated target: Brain excluding the optic lobes.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: https://orcid.org/0000-0002-1373-1705

larval central brain
type: Class
subclass of: central brain
subclass of: Restriction
  on property: part of
  some values from: larval brain
definition: Larval brain excluding the optic lobes.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-10-24T15:12:43Z
database_cross_reference: VFB:FBbt_00047889
has OBO namespace: fly_anatomy.ontology
id: FBbt:00047889

Axiom
annotated source: larval central brain
annotated property: definition
annotated target: Larval brain excluding the optic lobes.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

type III neuroblast
type: Class
subclass of: neuroblast
subclass of: Restriction
  on property: develops from
  some values from: type I neuroblast
subclass of: Restriction
  on property: expresses
  some values from: FBgn0010433
definition: Neuroblast that divides symmetrically to increase neuroblast numbers before generating neurons. They arise from a spatiotemporal conversion of classical self-renewing stem cells (type I neuroblasts).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-11-30T15:10:55Z
database_cross_reference: VFB:FBbt_00047992
has exact synonym: symmetrically-amplifying neuroblast
has OBO namespace: fly_anatomy.ontology
has related synonym: late neuroblast
id: FBbt:00047992

Axiom
annotated source: type III neuroblast
annotated property: definition
annotated target: Neuroblast that divides symmetrically to increase neuroblast numbers before generating neurons. They arise from a spatiotemporal conversion of classical self-renewing stem cells (type I neuroblasts).
database_cross_reference: FlyBase:FBrf0238554

Axiom
annotated source: type III neuroblast
annotated property: hasExactSynonym
annotated target: symmetrically-amplifying neuroblast
database_cross_reference: FlyBase:FBrf0238554

Axiom
annotated source: type III neuroblast
annotated property: hasRelatedSynonym
annotated target: late neuroblast
database_cross_reference: FlyBase:FBrf0238554

eye photoreceptor precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: eye photoreceptor cell
subclass of: larval neuron
subclass of: immature neuron
subclass of: Restriction
  on property: part of
  some values from: ommatidial precursor cluster
subclass of: Restriction
  on property: develops into
  some values from: eye photoreceptor cell
definition: Immature neuron of the eye disc that will develop into one of the photoreceptors (R1-R8) of the adult eye.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:22:38Z
database_cross_reference: VFB:FBbt_00048002
has exact synonym: developing photoreceptor
has exact synonym: future photoreceptor
has exact synonym: immature eye photoreceptor
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048002

Axiom
annotated source: eye photoreceptor precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into one of the photoreceptors (R1-R8) of the adult eye.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

Axiom
annotated source: eye photoreceptor precursor cell
annotated property: hasExactSynonym
annotated target: developing photoreceptor
database_cross_reference: FlyBase:FBrf0064798

Axiom
annotated source: eye photoreceptor precursor cell
annotated property: hasExactSynonym
annotated target: future photoreceptor
database_cross_reference: FlyBase:FBrf0064798

photoreceptor R1 precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: photoreceptor cell R1
subclass of: eye photoreceptor precursor cell
subclass of: Restriction
  on property: develops into
  some values from: photoreceptor cell R1
definition: Immature neuron of the eye disc that will develop into a photoreceptor cell R1 of the adult eye. It forms during the second mitotic wave and joins the precursor cells of the five-cell ommatidial precursor cluster to form the eight-cell ommatidial precursor cluster.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:30:15Z
database_cross_reference: VFB:FBbt_00048003
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048003

Axiom
annotated source: photoreceptor R1 precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into a photoreceptor cell R1 of the adult eye. It forms during the second mitotic wave and joins the precursor cells of the five-cell ommatidial precursor cluster to form the eight-cell ommatidial precursor cluster.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

photoreceptor R2 precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: photoreceptor cell R2
subclass of: eye photoreceptor precursor cell
subclass of: Restriction
  on property: develops into
  some values from: photoreceptor cell R2
definition: Immature neuron of the eye disc that will develop into a photoreceptor cell R2 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:45:20Z
database_cross_reference: VFB:FBbt_00048004
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048004

Axiom
annotated source: photoreceptor R2 precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into a photoreceptor cell R2 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

photoreceptor R3 precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: photoreceptor cell R3
subclass of: eye photoreceptor precursor cell
subclass of: Restriction
  on property: develops into
  some values from: photoreceptor cell R3
definition: Immature neuron of the eye disc that will develop into a photoreceptor cell R3 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:48:54Z
database_cross_reference: VFB:FBbt_00048005
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048005

Axiom
annotated source: photoreceptor R3 precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into a photoreceptor cell R3 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

photoreceptor R4 precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: photoreceptor cell R4
subclass of: eye photoreceptor precursor cell
subclass of: Restriction
  on property: develops into
  some values from: photoreceptor cell R4
definition: Immature neuron of the eye disc that will develop into a photoreceptor cell R4 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:49:23Z
database_cross_reference: VFB:FBbt_00048006
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048006

Axiom
annotated source: photoreceptor R4 precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into a photoreceptor cell R4 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

photoreceptor R5 precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: photoreceptor cell R5
subclass of: eye photoreceptor precursor cell
subclass of: Restriction
  on property: develops into
  some values from: photoreceptor cell R5
definition: Immature neuron of the eye disc that will develop into a photoreceptor cell R5 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:49:45Z
database_cross_reference: VFB:FBbt_00048007
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048007

Axiom
annotated source: photoreceptor R5 precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into a photoreceptor cell R5 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

photoreceptor R6 precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: photoreceptor cell R6
subclass of: eye photoreceptor precursor cell
subclass of: Restriction
  on property: develops into
  some values from: photoreceptor cell R6
definition: Immature neuron of the eye disc that will develop into a photoreceptor cell R6 of the adult eye. It forms during the second mitotic wave and joins the precursor cells of the five-cell ommatidial precursor cluster to form the eight-cell ommatidial precursor cluster.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:50:08Z
database_cross_reference: VFB:FBbt_00048008
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048008

Axiom
annotated source: photoreceptor R6 precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into a photoreceptor cell R6 of the adult eye. It forms during the second mitotic wave and joins the precursor cells of the five-cell ommatidial precursor cluster to form the eight-cell ommatidial precursor cluster.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

photoreceptor R7 precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: photoreceptor cell R7
subclass of: eye photoreceptor precursor cell
subclass of: Restriction
  on property: develops into
  some values from: photoreceptor cell R7
definition: Immature neuron of the eye disc that will develop into a photoreceptor cell R7 of the adult eye. It forms during the second mitotic wave and joins the precursor cells of the five-cell ommatidial precursor cluster to form the eight-cell ommatidial precursor cluster.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:51:40Z
database_cross_reference: VFB:FBbt_00048009
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048009

Axiom
annotated source: photoreceptor R7 precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into a photoreceptor cell R7 of the adult eye. It forms during the second mitotic wave and joins the precursor cells of the five-cell ommatidial precursor cluster to form the eight-cell ommatidial precursor cluster.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

photoreceptor R8 precursor cell
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: photoreceptor cell R8
subclass of: eye photoreceptor precursor cell
subclass of: Restriction
  on property: develops into
  some values from: photoreceptor cell R8
definition: Immature neuron of the eye disc that will develop into a photoreceptor cell R8 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2018-12-07T15:52:04Z
database_cross_reference: VFB:FBbt_00048010
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048010

Axiom
annotated source: photoreceptor R8 precursor cell
annotated property: definition
annotated target: Immature neuron of the eye disc that will develop into a photoreceptor cell R8 of the adult eye. It forms during the first mitotic wave and is part of the ommatidial precursor cluster from the early stage.
database_cross_reference: FlyBase:FBrf0064798
database_cross_reference: FlyBase:FBrf0222590

adult visual projection neuron
type: Class
equivalent class: Class
  intersection of: visual projection neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: visual projection neuron
subclass of: adult interneuron
subclass of: Restriction
  on property: part of
  some values from: adult brain
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: adult optic lobe
IAO_0000028: VPN
definition: Neuron that projects from the adult optic lobe to the central brain, conveying information from light stimuli.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2019-04-16T13:36:42Z
database_cross_reference: VFB:FBbt_00048286
has exact synonym: VPN
has exact synonym: adult VPN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048286

Axiom
annotated source: adult visual projection neuron
annotated property: definition
annotated target: Neuron that projects from the adult optic lobe to the central brain, conveying information from light stimuli.
database_cross_reference: FlyBase:FBrf0193607

Axiom
annotated source: adult visual projection neuron
annotated property: hasExactSynonym
annotated target: VPN
has synonym type: VFB SYMBOL

Axiom
annotated source: adult visual projection neuron
annotated property: hasExactSynonym
annotated target: adult VPN
database_cross_reference: FlyBase:FBrf0193607

visual projection neuron
type: Class
equivalent class: Class
  intersection of: projection neuron
  intersection of: Restriction
    on property: capable of part of
    some values from: GO_0050953
subclass of: projection neuron
subclass of: visual system neuron
definition: Neuron that projects from the optic lobe to the central brain, conveying information from light stimuli.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2019-04-16T14:01:06Z
database_cross_reference: VFB:FBbt_00048287
has exact synonym: VPN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048287

Axiom
annotated source: visual projection neuron
annotated property: definition
annotated target: Neuron that projects from the optic lobe to the central brain, conveying information from light stimuli.
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0237760

Axiom
annotated source: visual projection neuron
annotated property: hasExactSynonym
annotated target: VPN
database_cross_reference: FlyBase:FBrf0193607

larval optic neuropil
type: Class
subclass of: BFO_0000040
subclass of: larval sensory compartment
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0050953
definition: Small neuropil compartment of the larval optic lobe that contains the axons of photoreceptors. It is the first center for visual processing in the larval brain. It is largely surrounded by the outer optic anlage at earlier developmental stages and becomes sandwiched between the developing proximal medulla and the inner optic anlage by third instar. It is incorporated into the adult optic lobe as the accessory medulla.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2019-04-17T09:14:28Z
database_cross_reference: VFB:FBbt_00048289
database_cross_reference: larvalbrain_neuropil:379
database_cross_reference: larvalbrain_neuropil:557
has exact synonym: LON
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048289

Axiom
annotated source: larval optic neuropil
annotated property: definition
annotated target: Small neuropil compartment of the larval optic lobe that contains the axons of photoreceptors. It is the first center for visual processing in the larval brain. It is largely surrounded by the outer optic anlage at earlier developmental stages and becomes sandwiched between the developing proximal medulla and the inner optic anlage by third instar. It is incorporated into the adult optic lobe as the accessory medulla.
database_cross_reference: FlyBase:FBrf0215208

Axiom
annotated source: larval optic neuropil
annotated property: hasExactSynonym
annotated target: LON
database_cross_reference: FlyBase:FBrf0215208

adult lateral horn neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: receives synaptic input in region
    some values from: adult lateral horn
subclass of: adult neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: adult lateral horn
IAO_0000028: LHN
definition: Adult neuron that has dendritic arbors in the lateral horn (including local neurons). Many of these receive olfactory input from antennal lobe projection neurons.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2019-04-23T14:03:44Z
database_cross_reference: VFB:FBbt_00048293
has exact synonym: LHN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048293
comment: In contrast to previous usage, Dolan et al. (2019) (FBrf0242477) use 'lateral horn neuron' to refer to any neuron associated with the lateral horn, including input neurons. This class only includes neurons with dendritic arborizations in the lateral horn.

Axiom
annotated source: adult lateral horn neuron
annotated property: IAO_0000028
annotated target: LHN
database_cross_reference: FlyBase:FBrf0239324

Axiom
annotated source: adult lateral horn neuron
annotated property: definition
annotated target: Adult neuron that has dendritic arbors in the lateral horn (including local neurons). Many of these receive olfactory input from antennal lobe projection neurons.
database_cross_reference: FlyBase:FBrf0203179
database_cross_reference: FlyBase:FBrf0239324
database_cross_reference: FlyBase:FBrf0242628

Axiom
annotated source: adult lateral horn neuron
annotated property: hasExactSynonym
annotated target: LHN
database_cross_reference: FlyBase:FBrf0239324
has synonym type: VFB SYMBOL

medulla layer
type: Class
equivalent class: Class
  intersection of: synaptic neuropil layer
  intersection of: Restriction
    on property: part of
    some values from: medulla
subclass of: synaptic neuropil layer
subclass of: Restriction
  on property: part of
  some values from: medulla
definition: Any synaptic neuropil layer (FBbt:00040008) that is part of some medulla (FBbt:00003748).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2019-05-29T12:51:36Z
database_cross_reference: VFB:FBbt_00048343
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048343

Axiom
annotated source: medulla layer
annotated property: definition
annotated target: Any synaptic neuropil layer (FBbt:00040008) that is part of some medulla (FBbt:00003748).
database_cross_reference: FlyBase:FBrf0049410

lobula layer
type: Class
equivalent class: Class
  intersection of: synaptic neuropil layer
  intersection of: Restriction
    on property: part of
    some values from: lobula
subclass of: synaptic neuropil layer
subclass of: Restriction
  on property: part of
  some values from: lobula
definition: Any synaptic neuropil layer (FBbt:00040008) that is part of some lobula (FBbt:00003852).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2019-05-29T12:52:54Z
database_cross_reference: VFB:FBbt_00048344
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048344

Axiom
annotated source: lobula layer
annotated property: definition
annotated target: Any synaptic neuropil layer (FBbt:00040008) that is part of some lobula (FBbt:00003852).
database_cross_reference: FlyBase:FBrf0049410

lobula plate layer
type: Class
equivalent class: Class
  intersection of: synaptic neuropil layer
  intersection of: Restriction
    on property: part of
    some values from: lobula plate
subclass of: synaptic neuropil layer
subclass of: Restriction
  on property: part of
  some values from: lobula plate
definition: Any synaptic neuropil layer (FBbt:00040008) that is part of some lobula plate (FBbt:00003885).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2019-05-29T12:53:21Z
database_cross_reference: VFB:FBbt_00048345
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048345

Axiom
annotated source: lobula plate layer
annotated property: definition
annotated target: Any synaptic neuropil layer (FBbt:00040008) that is part of some lobula plate (FBbt:00003885).
database_cross_reference: FlyBase:FBrf0049410

wedge projection neuron
type: Class
equivalent class: Class
  intersection of: projection neuron
  intersection of: Restriction
    on property: receives synaptic input in region
    some values from: wedge
subclass of: projection neuron
subclass of: adult interneuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: wedge
IAO_0000028: WEDPN
definition: Any projection neuron (FBbt:00007392) that receives synaptic input in region some wedge (FBbt:00045027).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2019-12-10T11:40:53Z
database_cross_reference: VFB:FBbt_00048516
has exact synonym: WED projection neuron
has exact synonym: WEDPN
has exact synonym: WPN
has exact synonym: wedge PN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00048516

Axiom
annotated source: wedge projection neuron
annotated property: IAO_0000028
annotated target: WEDPN
database_cross_reference: FlyBase:FBrf0249560

Axiom
annotated source: wedge projection neuron
annotated property: definition
annotated target: Any projection neuron (FBbt:00007392) that receives synaptic input in region some wedge (FBbt:00045027).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: wedge projection neuron
annotated property: hasExactSynonym
annotated target: WEDPN
database_cross_reference: FlyBase:FBrf0249560
has synonym type: VFB SYMBOL

adult lateral horn local neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: adult lateral horn
subclass of: adult lateral horn neuron
subclass of: local neuron
subclass of: adult interneuron
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: adult lateral horn
subclass of: Restriction
  on property: synapses restricted to region
  some values from: adult lateral horn
IAO_0000028: LHLN
definition: Adult neuron with its arbors mostly restricted to the lateral horn.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-04-24T13:32:19Z
database_cross_reference: VFB:FBbt_00049285
has exact synonym: LHLN
has exact synonym: adult LHLN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049285

Axiom
annotated source: adult lateral horn local neuron
annotated property: definition
annotated target: Adult neuron with its arbors mostly restricted to the lateral horn.
database_cross_reference: FlyBase:FBrf0242477
database_cross_reference: FlyBase:FBrf0242628

Axiom
annotated source: adult lateral horn local neuron
annotated property: hasExactSynonym
annotated target: LHLN
has synonym type: VFB SYMBOL

Axiom
annotated source: adult lateral horn local neuron
annotated property: hasExactSynonym
annotated target: adult LHLN
database_cross_reference: FlyBase:FBrf0242628

adult central brain cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult brain cell body rind
  intersection of: Restriction
    on property: part of
    some values from: adult central brain
subclass of: adult brain cell body glial cell
subclass of: Restriction
  on property: part of
  some values from: adult central brain
definition: Glial cell of the adult that is associated with the cell body rind of the central brain. One cell can wrap around 20 to 100 cell bodies, but some cell bodies are wrapped by two neighboring glial cells (Kremer et al., 2017). They have an overall globular shape with fine lamellae protruding into surrounding areas (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-14T10:16:17Z
database_cross_reference: VFB:FBbt_00049489
has exact synonym: adult central brain CG
has exact synonym: adult central brain cortex associated glial cell
has OBO namespace: fly_anatomy.ontology
has related synonym: adult central brain cortex glial cell
id: FBbt:00049489

Axiom
annotated source: adult central brain cell body glial cell
annotated property: definition
annotated target: Glial cell of the adult that is associated with the cell body rind of the central brain. One cell can wrap around 20 to 100 cell bodies, but some cell bodies are wrapped by two neighboring glial cells (Kremer et al., 2017). They have an overall globular shape with fine lamellae protruding into surrounding areas (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult central brain cell body glial cell
annotated property: hasExactSynonym
annotated target: adult central brain CG
database_cross_reference: FlyBase:FBrf0234767

adult medulla astrocyte-like glial cell
type: Class
equivalent class: Class
  intersection of: astrocyte-like glial cell
  intersection of: Restriction
    on property: part of
    some values from: medulla
subclass of: adult medulla neuropil associated glial cell
subclass of: adult optic lobe astrocyte-like glial cell
definition: Astrocyte-like (reticular) glial cell located in the adult medulla neuropil. There are at least three subtypes and they show tiling and have a high structural density (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-15T15:31:31Z
database_cross_reference: VFB:FBbt_00049496
has exact synonym: adult medulla ALG
has exact synonym: adult medulla reticular glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049496

Axiom
annotated source: adult medulla astrocyte-like glial cell
annotated property: definition
annotated target: Astrocyte-like (reticular) glial cell located in the adult medulla neuropil. There are at least three subtypes and they show tiling and have a high structural density (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult medulla astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: adult medulla ALG
database_cross_reference: FlyBase:FBrf0234767

adult medulla ensheathing glial cell
type: Class
equivalent class: Class
  intersection of: ensheathing glial cell
  intersection of: Restriction
    on property: part of
    some values from: medulla
subclass of: adult medulla neuropil associated glial cell
subclass of: adult optic lobe ensheathing glial cell
definition: Ensheathing glial cell located in the adult medulla neuropil. There are at least two subtypes, forming a dense sheath around the distal medulla and serpentine layer, where their cell bodies are found (Kremer et al., 2017). Rather than having its own ensheathing glia, the proximal medulla is invaded by fine processes from the inner chiasm glia (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-15T15:35:32Z
database_cross_reference: VFB:FBbt_00049497
has exact synonym: adult medulla EG
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049497

Axiom
annotated source: adult medulla ensheathing glial cell
annotated property: definition
annotated target: Ensheathing glial cell located in the adult medulla neuropil. There are at least two subtypes, forming a dense sheath around the distal medulla and serpentine layer, where their cell bodies are found (Kremer et al., 2017). Rather than having its own ensheathing glia, the proximal medulla is invaded by fine processes from the inner chiasm glia (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult medulla ensheathing glial cell
annotated property: hasExactSynonym
annotated target: adult medulla EG
database_cross_reference: FlyBase:FBrf0234767

adult medulla cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: cell body rind of adult medulla
subclass of: adult optic lobe cell body glial cell
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult medulla
definition: Glial cell located in the cell body rind of the medulla. It is similar to cell body glial cells of the central brain (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-15T15:51:14Z
database_cross_reference: VFB:FBbt_00049498
has exact synonym: adult medulla CG
has exact synonym: adult medulla cortex glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049498

Axiom
annotated source: adult medulla cell body glial cell
annotated property: definition
annotated target: Glial cell located in the cell body rind of the medulla. It is similar to cell body glial cells of the central brain (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult medulla cell body glial cell
annotated property: hasExactSynonym
annotated target: adult medulla CG
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult medulla cell body glial cell
annotated property: hasExactSynonym
annotated target: adult medulla cortex glial cell
database_cross_reference: FlyBase:FBrf0234767

adult lobula complex astrocyte-like glial cell
type: Class
equivalent class: Class
  intersection of: astrocyte-like glial cell
  intersection of: Restriction
    on property: part of
    some values from: lobula complex
subclass of: adult optic lobe astrocyte-like glial cell
subclass of: Restriction
  on property: part of
  some values from: lobula complex
definition: Astrocyte-like (reticular) glial cell with its soma at the surface of either the adult lobula or lobula plate (lobula complex) neuropil regions (Kremer et al., 2017). These cells take many shapes and sizes and may form branches into one or both neuropils (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-18T12:24:59Z
database_cross_reference: VFB:FBbt_00049501
has exact synonym: adult lobula complex ALG
has exact synonym: adult lobula complex reticular glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049501
comment: Cells additionally projecting into the medulla are mentioned, but not shown in images or diagram, by Kremer et al. (2017). Not clear if these should fall under this class - part_of may need revising - https://orcid.org/0000-0002-1373-1705.

Axiom
annotated source: adult lobula complex astrocyte-like glial cell
annotated property: definition
annotated target: Astrocyte-like (reticular) glial cell with its soma at the surface of either the adult lobula or lobula plate (lobula complex) neuropil regions (Kremer et al., 2017). These cells take many shapes and sizes and may form branches into one or both neuropils (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lobula complex astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: adult lobula complex ALG
database_cross_reference: FlyBase:FBrf0234767

adult lobula complex ensheathing glial cell
type: Class
equivalent class: Class
  intersection of: ensheathing glial cell
  intersection of: Restriction
    on property: part of
    some values from: lobula complex
subclass of: adult optic lobe ensheathing glial cell
subclass of: Restriction
  on property: part of
  some values from: lobula complex
definition: Ensheathing glial cell with its soma at the surface of the either the lobula or lobula plate (lobula complex) neuropil regions (Kremer et al., 2017). These cells form columnar processes perpendicular to the neuropil margin, as well as tangential processes parallel to the margin (Kremer et al., 2017). They form a complex three-dimensional arrangement of branches (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-18T12:35:41Z
database_cross_reference: VFB:FBbt_00049502
has exact synonym: adult lobula complex EG
has OBO namespace: fly_anatomy.ontology
has related synonym: adult lobula complex EGN
id: FBbt:00049502

Axiom
annotated source: adult lobula complex ensheathing glial cell
annotated property: definition
annotated target: Ensheathing glial cell with its soma at the surface of the either the lobula or lobula plate (lobula complex) neuropil regions (Kremer et al., 2017). These cells form columnar processes perpendicular to the neuropil margin, as well as tangential processes parallel to the margin (Kremer et al., 2017). They form a complex three-dimensional arrangement of branches (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lobula complex ensheathing glial cell
annotated property: hasExactSynonym
annotated target: adult lobula complex EG
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lobula complex ensheathing glial cell
annotated property: hasRelatedSynonym
annotated target: adult lobula complex EGN
database_cross_reference: FlyBase:FBrf0234767

larval lateral horn local interneuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: embryonic/larval lateral horn
subclass of: larval lateral horn neuron
subclass of: local neuron
subclass of: larval interneuron
subclass of: Restriction
  on property: synapses restricted to region
  some values from: embryonic/larval lateral horn
definition: Any neuron (FBbt:00005106) that synapses restricted to region some embryonic/larval lateral horn (FBbt:00111688).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-26T14:56:31Z
database_cross_reference: VFB:FBbt_00049520
has exact synonym: larval LH-LN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049520

Axiom
annotated source: larval lateral horn local interneuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that synapses restricted to region some embryonic/larval lateral horn (FBbt:00111688).
database_cross_reference: FlyBase:FBrf0240828

Axiom
annotated source: larval lateral horn local interneuron
annotated property: hasExactSynonym
annotated target: larval LH-LN
database_cross_reference: FlyBase:FBrf0240828

Notch ON hemilineage neuron
type: Class
subclass of: neuron
definition: Neuron belonging to a hemilineage that has active Notch signaling.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-28T14:28:52Z
database_cross_reference: VFB:FBbt_00049539
has exact synonym: A hemilineage neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049539

Axiom
annotated source: Notch ON hemilineage neuron
annotated property: definition
annotated target: Neuron belonging to a hemilineage that has active Notch signaling.
database_cross_reference: FlyBase:FBrf0245463

Axiom
annotated source: Notch ON hemilineage neuron
annotated property: hasExactSynonym
annotated target: A hemilineage neuron
database_cross_reference: FlyBase:FBrf0245463

Notch OFF hemilineage neuron
type: Class
subclass of: neuron
definition: Neuron belonging to a hemilineage that does not have active Notch signaling.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-28T14:41:21Z
database_cross_reference: VFB:FBbt_00049540
has exact synonym: B hemilineage neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049540

Axiom
annotated source: Notch OFF hemilineage neuron
annotated property: definition
annotated target: Neuron belonging to a hemilineage that does not have active Notch signaling.
database_cross_reference: FlyBase:FBrf0245463

Axiom
annotated source: Notch OFF hemilineage neuron
annotated property: hasExactSynonym
annotated target: B hemilineage neuron
database_cross_reference: FlyBase:FBrf0245463

Notch ON hemilineage secondary neuron
type: Class
equivalent class: Class
  intersection of: secondary neuron
  intersection of: Notch ON hemilineage neuron
subclass of: secondary neuron
subclass of: Notch ON hemilineage neuron
definition: Secondary neuron belonging to a hemilineage that has active Notch signaling.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-28T14:43:25Z
database_cross_reference: VFB:FBbt_00049541
has exact synonym: A hemilineage secondary neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049541

Axiom
annotated source: Notch ON hemilineage secondary neuron
annotated property: definition
annotated target: Secondary neuron belonging to a hemilineage that has active Notch signaling.
database_cross_reference: FlyBase:FBrf0245463

Notch OFF hemilineage secondary neuron
type: Class
equivalent class: Class
  intersection of: secondary neuron
  intersection of: Notch OFF hemilineage neuron
subclass of: secondary neuron
subclass of: Notch OFF hemilineage neuron
definition: Secondary neuron belonging to a hemilineage that does not have active Notch signaling.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-05-28T14:46:11Z
database_cross_reference: VFB:FBbt_00049542
has exact synonym: B hemilineage secondary neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049542

Axiom
annotated source: Notch OFF hemilineage secondary neuron
annotated property: definition
annotated target: Secondary neuron belonging to a hemilineage that does not have active Notch signaling.
database_cross_reference: FlyBase:FBrf0245463

cell body rind of larval central nervous system
type: Class
subclass of: cell body rind of the central nervous system
subclass of: Restriction
  on property: part of
  some values from: larval central nervous system
definition: Superficial layer of neuronal cell bodies and glia that overlies the neuropil of the larval central nervous system.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-06-15T13:37:38Z
database_cross_reference: VFB:FBbt_00049602
has exact synonym: larval cortex
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049602

Axiom
annotated source: cell body rind of larval central nervous system
annotated property: definition
annotated target: Superficial layer of neuronal cell bodies and glia that overlies the neuropil of the larval central nervous system.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

cell body rind of adult central nervous system
type: Class
subclass of: cell body rind of the central nervous system
subclass of: Restriction
  on property: part of
  some values from: adult central nervous system
definition: Superficial layer of neuronal cell bodies and glia that overlies the neuropil of the adult central nervous system (brain or ventral nerve cord).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-06-15T13:45:27Z
database_cross_reference: VFB:FBbt_00049603
has exact synonym: adult cortex
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049603

Axiom
annotated source: cell body rind of adult central nervous system
annotated property: definition
annotated target: Superficial layer of neuronal cell bodies and glia that overlies the neuropil of the adult central nervous system (brain or ventral nerve cord).
database_cross_reference: https://orcid.org/0000-0002-1373-1705

larval brain cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: cell body rind of larval brain
subclass of: embryonic/larval cell body glial cell
subclass of: Restriction
  on property: part of
  some values from: cell body rind of larval brain
definition: Glial cell located amongst neuronal cell bodies in the cortex of the embryonic/larval brain.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-06-15T14:20:49Z
database_cross_reference: VFB:FBbt_00049604
has exact synonym: embryonic/larval brain cortex glial cell
has exact synonym: larval brain CBG
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049604

Axiom
annotated source: larval brain cell body glial cell
annotated property: definition
annotated target: Glial cell located amongst neuronal cell bodies in the cortex of the embryonic/larval brain.
database_cross_reference: FlyBase:FBrf0237238

adult optic lobe astrocyte-like glial cell
type: Class
equivalent class: Class
  intersection of: astrocyte-like glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult optic lobe
subclass of: adult astrocyte-like glial cell
subclass of: adult optic lobe neuropil associated glial cell
definition: Astrocyte-like (reticular) glial cell found in the optic lobe (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-09-21T08:28:16Z
database_cross_reference: VFB:FBbt_00049808
has exact synonym: adult optic lobe ALG
has exact synonym: adult optic lobe reticular glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049808

Axiom
annotated source: adult optic lobe astrocyte-like glial cell
annotated property: definition
annotated target: Astrocyte-like (reticular) glial cell found in the optic lobe (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

optic glomerulus of the AOTU
type: Class
equivalent class: Class
  intersection of: optic glomerulus
  intersection of: Restriction
    on property: part of
    some values from: anterior optic tubercle
subclass of: optic glomerulus
subclass of: Restriction
  on property: part of
  some values from: anterior optic tubercle
definition: Any optic glomerulus (FBbt:00003698) that is part of some anterior optic tubercle (FBbt:00007059).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-09-23T13:33:30Z
database_cross_reference: VFB:FBbt_00049811
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049811

Axiom
annotated source: optic glomerulus of the AOTU
annotated property: definition
annotated target: Any optic glomerulus (FBbt:00003698) that is part of some anterior optic tubercle (FBbt:00007059).
database_cross_reference: FlyBase:FBrf0246888

adult subesophageal zone output neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: receives synaptic input in region
    some values from: adult subesophageal zone
  intersection of: Restriction
    on property: sends synaptic output to region
    some values from: adult supraesophageal zone
subclass of: adult interneuron
subclass of: input/output neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: adult subesophageal zone
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: adult supraesophageal zone
IAO_0000028: SEZON
definition: Adult neuron that ascends from the subesophageal zone (Otto et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-10-21T14:25:04Z
database_cross_reference: VFB:FBbt_00049858
has exact synonym: SEZON
has exact synonym: adult SEZON
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049858
comment: Potential gustatory projection neurons (Otto et al., 2020).

Axiom
annotated source: adult subesophageal zone output neuron
annotated property: IAO_0000028
annotated target: SEZON
database_cross_reference: FlyBase:FBrf0246510

Axiom
annotated source: adult subesophageal zone output neuron
annotated property: definition
annotated target: Adult neuron that ascends from the subesophageal zone (Otto et al., 2020).
database_cross_reference: FlyBase:FBrf0246510
database_cross_reference: FlyBase:FBrf0248215

Axiom
annotated source: adult subesophageal zone output neuron
annotated property: hasExactSynonym
annotated target: SEZON
database_cross_reference: FlyBase:FBrf0246510
has synonym type: VFB SYMBOL

Axiom
annotated source: adult subesophageal zone output neuron
annotated property: hasExactSynonym
annotated target: adult SEZON
database_cross_reference: FlyBase:FBrf0248215

transmedullary neuron Tm29
type: Class
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: adult transmedullary CB3851 neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm29
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5B
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 5B
IAO_0000028: Tm29
definition: Transmedullary neuron that receives most of its input in around 5 columns of medulla layer M6, where it also has a small number of presynapses (Nern et al., 2025). It also has a small amount of arborization in the rest of M3-M8 (Nern et al., 2025). It crosses the second optic chiasm and has mixed pre- and post-synapses in around 3 columns of lobula layer 5B (Nern et al., 2025). It is glutamatergic (Davis et al., 2020). There are around 170-270 of these cells per hemisphere (Nern et al., 2025).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-11-20T09:32:15Z
database_cross_reference: VFB:FBbt_00049916
has exact synonym: Tm29
has exact synonym: Tm5d
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049916

Axiom
annotated source: transmedullary neuron Tm29
annotated property: definition
annotated target: Transmedullary neuron that receives most of its input in around 5 columns of medulla layer M6, where it also has a small number of presynapses (Nern et al., 2025). It also has a small amount of arborization in the rest of M3-M8 (Nern et al., 2025). It crosses the second optic chiasm and has mixed pre- and post-synapses in around 3 columns of lobula layer 5B (Nern et al., 2025). It is glutamatergic (Davis et al., 2020). There are around 170-270 of these cells per hemisphere (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0260545
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: transmedullary neuron Tm29
annotated property: hasExactSynonym
annotated target: Tm29
has synonym type: VFB SYMBOL

Axiom
annotated source: transmedullary neuron Tm29
annotated property: hasExactSynonym
annotated target: Tm5d
database_cross_reference: FlyBase:FBrf0260545
database_cross_reference: FlyBase:FBrf0262545

LC6 optic glomerulus
type: Class
subclass of: optic glomerulus of the PVLP
subclass of: Restriction
  on property: receives input from
  some values from: lobula columnar neuron LC6
definition: Optic glomerulus formed by the axon terminals of lobula columnar (LC) 6 neurons (Wu et al., 2016; Morimoto et al., 2020). It is found in the posterior ventrolateral protocerebrum (Wu et al., 2016). It displays very coarse retinotopic organization (Morimoto et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2020-12-16T14:07:47Z
database_cross_reference: VFB:FBbt_00049981
has OBO namespace: fly_anatomy.ontology
id: FBbt:00049981

Axiom
annotated source: LC6 optic glomerulus
annotated property: definition
annotated target: Optic glomerulus formed by the axon terminals of lobula columnar (LC) 6 neurons (Wu et al., 2016; Morimoto et al., 2020). It is found in the posterior ventrolateral protocerebrum (Wu et al., 2016). It displays very coarse retinotopic organization (Morimoto et al., 2020).
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0247630

cell body rind of adult posterior lobula plate
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult lobula plate
subclass of: Restriction
  on property: continuous with
  some values from: lobula plate
definition: Adult cell body rind region that overlies the posterior surface of the lobula plate (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00051036
has exact synonym: rLOPp
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051036

Axiom
annotated source: cell body rind of adult posterior lobula plate
annotated property: definition
annotated target: Adult cell body rind region that overlies the posterior surface of the lobula plate (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult posterior lobula plate
annotated property: hasExactSynonym
annotated target: rLOPp
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

cell body rind of adult lateral medulla
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult medulla
subclass of: Restriction
  on property: continuous with
  some values from: medulla
definition: Adult cell body rind region that overlies the lateral surface of the medulla (Ito et al., 2014).
database_cross_reference: VFB:FBbt_00051041
has exact synonym: rMEl
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051041

Axiom
annotated source: cell body rind of adult lateral medulla
annotated property: definition
annotated target: Adult cell body rind region that overlies the lateral surface of the medulla (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult lateral medulla
annotated property: hasExactSynonym
annotated target: rMEl
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

larval subesophageal zone
type: Class
equivalent class: Class
  intersection of: subesophageal zone
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: subesophageal zone
subclass of: Restriction
  on property: part of
  some values from: larval central nervous system
definition: Neuropil mass below the larval esophagus consisting of the gnathal ganglion and part of the tritocerebrum.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-02-26T11:25:02Z
database_cross_reference: VFB:FBbt_00051067
has exact synonym: larval SEZ
has OBO namespace: fly_anatomy.ontology
has related synonym: larval subesophageal ganglion
id: FBbt:00051067
comment: This is analogous to the adult term based on Ito et al. (2014), reflecting location relative to the esophagus, rather than segmental identity.

Axiom
annotated source: larval subesophageal zone
annotated property: definition
annotated target: Neuropil mass below the larval esophagus consisting of the gnathal ganglion and part of the tritocerebrum.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0229672
database_cross_reference: FlyBase:FBrf0237252

Axiom
annotated source: larval subesophageal zone
annotated property: hasExactSynonym
annotated target: larval SEZ
database_cross_reference: FlyBase:FBrf0237252

subesophageal zone
type: Class
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: central nervous system
definition: Neuropil mass below the esophagus encompassing the three gnathal neuromeres and any regions of the cephalic (supraesophageal) neuromeres situated below the esophagus (Ito et al., 2014).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-02-26T11:59:59Z
database_cross_reference: VFB:FBbt_00051068
has exact synonym: SEZ
has OBO namespace: fly_anatomy.ontology
has related synonym: subesophageal ganglion
id: FBbt:00051068

Axiom
annotated source: subesophageal zone
annotated property: definition
annotated target: Neuropil mass below the esophagus encompassing the three gnathal neuromeres and any regions of the cephalic (supraesophageal) neuromeres situated below the esophagus (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: subesophageal zone
annotated property: hasExactSynonym
annotated target: SEZ
database_cross_reference: FlyBase:FBrf0224194

supraesophageal zone
type: Class
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: supraesophageal ganglion
definition: Neuropil mass above the esophagus (Ito et al., 2014). It is part of the cerebral (supraesophageal) ganglion (Ito et al., 2014).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-02-26T13:05:56Z
has broad synonym: supraesophageal ganglion
database_cross_reference: VFB:FBbt_00051069
has exact synonym: SPZ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051069

Axiom
annotated source: supraesophageal zone
annotated property: definition
annotated target: Neuropil mass above the esophagus (Ito et al., 2014). It is part of the cerebral (supraesophageal) ganglion (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: supraesophageal zone
annotated property: hasExactSynonym
annotated target: SPZ
database_cross_reference: FlyBase:FBrf0224194

larval supraesophageal zone
type: Class
equivalent class: Class
  intersection of: supraesophageal zone
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: supraesophageal zone
subclass of: Restriction
  on property: part of
  some values from: larval brain
definition: Neuropil mass above the larval esophagus consisting of the protocerebral and deutocerebral neuromeres and part of the tritocerebrum.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-02-26T13:07:57Z
has broad synonym: larval supraesophageal ganglion
database_cross_reference: VFB:FBbt_00051070
has exact synonym: larval SPZ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051070
comment: This is analogous to the adult term based on Ito et al. (2014), reflecting location relative to the esophagus, rather than segmental identity.

Axiom
annotated source: larval supraesophageal zone
annotated property: definition
annotated target: Neuropil mass above the larval esophagus consisting of the protocerebral and deutocerebral neuromeres and part of the tritocerebrum.
database_cross_reference: FlyBase:FBrf0224194

larval lateral horn neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: embryonic/larval lateral horn
subclass of: larval neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: embryonic/larval lateral horn
definition: Any neuron (FBbt:00005106) that has synaptic IO in region some embryonic/larval lateral horn (FBbt:00111688).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-04-07T12:40:06Z
database_cross_reference: VFB:FBbt_00051206
has exact synonym: embryonic/larval lateral horn neuron
has exact synonym: larval LH neuron
has exact synonym: larval LHN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051206

Axiom
annotated source: larval lateral horn neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that has synaptic IO in region some embryonic/larval lateral horn (FBbt:00111688).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: larval lateral horn neuron
annotated property: hasExactSynonym
annotated target: larval LH neuron
database_cross_reference: FlyBase:FBrf0251872

Axiom
annotated source: larval lateral horn neuron
annotated property: hasExactSynonym
annotated target: larval LHN
database_cross_reference: FlyBase:FBrf0251872

small unit of anterior optic tubercle
type: Class
subclass of: synaptic neuropil subdomain
subclass of: Restriction
  on property: part of
  some values from: anterior optic tubercle
definition: Region of the adult anterior optic tubercle that receives input from neurons that project from the medulla (Timaeus et al., 2020). It consists of the anterior optic tubercle excluding the medial zone (large unit) (Timaeus et al., 2020). It can be further subdivided based on the innervation patterns of medulla-tubercle and tubercle-bulb neurons (Timaeus et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-04-21T14:29:51Z
database_cross_reference: VFB:FBbt_00051217
has exact synonym: AOTU SU
has exact synonym: AOTUsu
has exact synonym: lower unit of AOTU
has exact synonym: lower unit of anterior optic tubercle
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051217

Axiom
annotated source: small unit of anterior optic tubercle
annotated property: definition
annotated target: Region of the adult anterior optic tubercle that receives input from neurons that project from the medulla (Timaeus et al., 2020). It consists of the anterior optic tubercle excluding the medial zone (large unit) (Timaeus et al., 2020). It can be further subdivided based on the innervation patterns of medulla-tubercle and tubercle-bulb neurons (Timaeus et al., 2020).
database_cross_reference: FlyBase:FBrf0247314

Axiom
annotated source: small unit of anterior optic tubercle
annotated property: hasExactSynonym
annotated target: AOTU SU
database_cross_reference: FlyBase:FBrf0247314

Axiom
annotated source: small unit of anterior optic tubercle
annotated property: hasExactSynonym
annotated target: AOTUsu
database_cross_reference: FlyBase:FBrf0254510

Axiom
annotated source: small unit of anterior optic tubercle
annotated property: hasExactSynonym
annotated target: lower unit of AOTU
database_cross_reference: FlyBase:FBrf0257023

Axiom
annotated source: small unit of anterior optic tubercle
annotated property: hasExactSynonym
annotated target: lower unit of anterior optic tubercle
database_cross_reference: FlyBase:FBrf0257023

adult medulla-tubercle neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: receives synaptic input in region
    some values from: medulla
  intersection of: Restriction
    on property: sends synaptic output to region
    some values from: anterior optic tubercle
subclass of: anterior ectoderm derivative
subclass of: adult visual projection neuron
subclass of: Restriction
  on property: fasciculates with
  some values from: adult anterior optic tract
subclass of: Restriction
  on property: develops from
  some values from: optic neuroblast
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: small unit of anterior optic tubercle
IAO_0000028: MeTu
definition: Neuron that connects the medulla to the anterior optic tubercle (AOTU), via the anterior optic tract, innervating the small unit of the AOTU (Timaeus et al., 2020; Hulse et al., 2021; Kandimalla et al., 2023). It is derived from an optic neuroblast (Kandimalla et al., 2023). There are around 500 of these cells per hemisphere (Nern et al., 2025).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-04-22T11:23:51Z
database_cross_reference: VFB:FBbt_00051228
has exact synonym: MT neuron
has exact synonym: MeTu
has exact synonym: MeTu neuron
has exact synonym: adult medullar-tubercular neuron
has exact synonym: medullo-tubercular neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051228

Axiom
annotated source: adult medulla-tubercle neuron
annotated property: IAO_0000028
annotated target: MeTu
database_cross_reference: FlyBase:FBrf0235330

Axiom
annotated source: adult medulla-tubercle neuron
annotated property: definition
annotated target: Neuron that connects the medulla to the anterior optic tubercle (AOTU), via the anterior optic tract, innervating the small unit of the AOTU (Timaeus et al., 2020; Hulse et al., 2021; Kandimalla et al., 2023). It is derived from an optic neuroblast (Kandimalla et al., 2023). There are around 500 of these cells per hemisphere (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0224242
database_cross_reference: FlyBase:FBrf0252485
database_cross_reference: FlyBase:FBrf0254510
database_cross_reference: FlyBase:FBrf0257023
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: adult medulla-tubercle neuron
annotated property: hasExactSynonym
annotated target: MT neuron
database_cross_reference: FlyBase:FBrf0236205

Axiom
annotated source: adult medulla-tubercle neuron
annotated property: hasExactSynonym
annotated target: MeTu
database_cross_reference: FlyBase:FBrf0235330
has synonym type: VFB SYMBOL

Axiom
annotated source: adult medulla-tubercle neuron
annotated property: hasExactSynonym
annotated target: MeTu neuron
database_cross_reference: FlyBase:FBrf0235330

Axiom
annotated source: adult medulla-tubercle neuron
annotated property: hasExactSynonym
annotated target: adult medullar-tubercular neuron
database_cross_reference: FlyBase:FBrf0247314

Axiom
annotated source: adult medulla-tubercle neuron
annotated property: hasExactSynonym
annotated target: medullo-tubercular neuron
database_cross_reference: FlyBase:FBrf0235330

larval descending neuron to SEZ
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: cell body rind of larval brain
  intersection of: Restriction
    on property: has synaptic IO in region
    some values from: larval subesophageal zone
subclass of: larval descending neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: larval subesophageal zone
definition: Descending neuron of the larva with its soma in the brain and processes extending into the subesophageal zone (Winding et al. (2023).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-08-17T13:08:04Z
database_cross_reference: VFB:FBbt_00051301
has exact synonym: larval DNSEZ
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051301
comment: Winding et al. (2023) appear to exclude neurons that continue to the VNC, but these are not excluded from this class.

Axiom
annotated source: larval descending neuron to SEZ
annotated property: definition
annotated target: Descending neuron of the larva with its soma in the brain and processes extending into the subesophageal zone (Winding et al. (2023).
database_cross_reference: FlyBase:FBrf0255988

Axiom
annotated source: larval descending neuron to SEZ
annotated property: hasExactSynonym
annotated target: larval DNSEZ
database_cross_reference: FlyBase:FBrf0255988

larval descending neuron
type: Class
subclass of: supraesophageal ganglion neuron
subclass of: larval CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of larval brain
definition: Descending neuron of the larva with its soma in the brain and processes extending further into the CNS, reaching the gnathal ganglion or ventral nerve cord (Winding et al. (2023).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-08-17T13:13:54Z
database_cross_reference: VFB:FBbt_00051302
has exact synonym: larval DN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051302
comment: Ignores directionality of information flow, similar to 'adult descending neuron'.

Axiom
annotated source: larval descending neuron
annotated property: definition
annotated target: Descending neuron of the larva with its soma in the brain and processes extending further into the CNS, reaching the gnathal ganglion or ventral nerve cord (Winding et al. (2023).
database_cross_reference: FlyBase:FBrf0255988

adult sensory region of subesophageal zone
type: Class
equivalent class: Class
  intersection of: synaptic neuropil subdomain
  intersection of: Restriction
    on property: part of
    some values from: adult subesophageal zone
  intersection of: Restriction
    on property: capable of part of
    some values from: GO_0007600
subclass of: BFO_0000040
subclass of: synaptic neuropil subdomain
subclass of: Restriction
  on property: part of
  some values from: adult subesophageal zone
subclass of: Restriction
  on property: overlaps
  some values from: sensory system
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0007600
definition: Synaptic neuropil subdomain of the adult subesophageal zone that houses the axon terminals of sensory neurons (Miyazaki and Ito, 2010; Kendroud et al., 2018). Larger domains can be defined based on the projection patterns of neurons entering the brain via particular roots of the maxillary-labial, pharyngeal and antennal nerves (Kendroud et al., 2018). Many smaller domains, usually subdomains of the larger regions, can also be defined based on neuron morphology and function (Miyazaki and Ito, 2010; Munch et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-07-02T12:39:01Z
database_cross_reference: VFB:FBbt_00051393
has exact synonym: adult SEZ sensory region
has narrow synonym: adult labellar gustatory association center
has narrow synonym: adult labial gustatory center
has narrow synonym: adult pharyngeal gustatory association center
has OBO namespace: fly_anatomy.ontology
has related synonym: PGC
has related synonym: adult primary gustatory center
has related synonym: primary taste sensory neuropil
has related synonym: taste-sensory region glomerulus
id: FBbt:00051393

Axiom
annotated source: adult sensory region of subesophageal zone
annotated property: definition
annotated target: Synaptic neuropil subdomain of the adult subesophageal zone that houses the axon terminals of sensory neurons (Miyazaki and Ito, 2010; Kendroud et al., 2018). Larger domains can be defined based on the projection patterns of neurons entering the brain via particular roots of the maxillary-labial, pharyngeal and antennal nerves (Kendroud et al., 2018). Many smaller domains, usually subdomains of the larger regions, can also be defined based on neuron morphology and function (Miyazaki and Ito, 2010; Munch et al., 2022).
database_cross_reference: FlyBase:FBrf0211916
database_cross_reference: FlyBase:FBrf0237251
database_cross_reference: FlyBase:FBrf0254134

Axiom
annotated source: adult sensory region of subesophageal zone
annotated property: hasNarrowSynonym
annotated target: adult labellar gustatory association center
database_cross_reference: FlyBase:FBrf0237251

Axiom
annotated source: adult sensory region of subesophageal zone
annotated property: hasNarrowSynonym
annotated target: adult labial gustatory center
database_cross_reference: FlyBase:FBrf0237251

Axiom
annotated source: adult sensory region of subesophageal zone
annotated property: hasRelatedSynonym
annotated target: PGC
database_cross_reference: FlyBase:FBrf0211916

Axiom
annotated source: adult sensory region of subesophageal zone
annotated property: hasRelatedSynonym
annotated target: adult primary gustatory center
database_cross_reference: FlyBase:FBrf0211916

Axiom
annotated source: adult sensory region of subesophageal zone
annotated property: hasRelatedSynonym
annotated target: primary taste sensory neuropil
database_cross_reference: FlyBase:FBrf0042883

Axiom
annotated source: adult sensory region of subesophageal zone
annotated property: hasRelatedSynonym
annotated target: taste-sensory region glomerulus
database_cross_reference: FlyBase:FBrf0055600

larval sensory compartment
type: Class
subclass of: synaptic neuropil domain
subclass of: Restriction
  on property: part of
  some values from: larval central nervous system
definition: Neuropil region of the larval central nervous system that is defined by the axonal projections of sensory neurons (Kendroud et al., 2018; Miroschnikow et al., 2018).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-07-05T12:02:43Z
database_cross_reference: VFB:FBbt_00051405
has exact synonym: larval sensory column
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051405

Axiom
annotated source: larval sensory compartment
annotated property: definition
annotated target: Neuropil region of the larval central nervous system that is defined by the axonal projections of sensory neurons (Kendroud et al., 2018; Miroschnikow et al., 2018).
database_cross_reference: FlyBase:FBrf0237251
database_cross_reference: FlyBase:FBrf0240975

Axiom
annotated source: larval sensory compartment
annotated property: hasExactSynonym
annotated target: larval sensory column
database_cross_reference: FlyBase:FBrf0237251

developing neuron
type: Class
subclass of: neuron
subclass of: somatic precursor cell
definition: Neuron that is in a transient state between birth and its first mature morphology or between its larval and adult morphologies.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-07-16T10:00:44Z
database_cross_reference: VFB:FBbt_00051423
has narrow synonym: immature neuron
has OBO namespace: fly_anatomy.ontology
has related synonym: differentiating neuron
id: FBbt:00051423

Axiom
annotated source: developing neuron
annotated property: definition
annotated target: Neuron that is in a transient state between birth and its first mature morphology or between its larval and adult morphologies.
database_cross_reference: FlyBase:FBrf0161044
database_cross_reference: FlyBase:FBrf0247750

immature neuron
type: Class
subclass of: developing neuron
definition: Neuron that is in a transient, immature, state between birth and its first mature morphology.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-07-16T10:52:33Z
database_cross_reference: VFB:FBbt_00051424
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051424

Axiom
annotated source: immature neuron
annotated property: definition
annotated target: Neuron that is in a transient, immature, state between birth and its first mature morphology.
database_cross_reference: FlyBase:FBrf0156020
database_cross_reference: FlyBase:FBrf0247750

local neuron
type: Class
subclass of: interneuron
definition: Neuron of the central nervous system that has the majority of its inputs and outputs in close proximity within the same region of the neuropil. Some arbors may spread outside of the region, but without sufficient polarity to define the neuron as an input or output neuron.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-09-22T08:47:38Z
database_cross_reference: VFB:FBbt_00051493
has exact synonym: local interneuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051493

Axiom
annotated source: local neuron
annotated property: definition
annotated target: Neuron of the central nervous system that has the majority of its inputs and outputs in close proximity within the same region of the neuropil. Some arbors may spread outside of the region, but without sufficient polarity to define the neuron as an input or output neuron.
database_cross_reference: FlyBase:FBrf0232785
database_cross_reference: FlyBase:FBrf0242477

efferent neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: cell body rind of the central nervous system
  intersection of: Restriction
    on property: fasciculates with
    some values from: nerve
subclass of: CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of the central nervous system
subclass of: Restriction
  on property: fasciculates with
  some values from: nerve
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: central nervous system
definition: Neuron that transmits information out of the central nervous system (CNS). It has its soma in the cell body rind of the CNS, a dendrite in the CNS and an axon projecting through a nerve (Prokop, 2006).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-11-02T13:57:50Z
database_cross_reference: VFB:FBbt_00051963
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051963

Axiom
annotated source: efferent neuron
annotated property: definition
annotated target: Neuron that transmits information out of the central nervous system (CNS). It has its soma in the cell body rind of the CNS, a dendrite in the CNS and an axon projecting through a nerve (Prokop, 2006).
database_cross_reference: FlyBase:FBrf0192553

adult efferent neuron
type: Class
equivalent class: Class
  intersection of: efferent neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: efferent neuron
subclass of: adult CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult central nervous system
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: adult central nervous system
definition: Any efferent neuron of the adult.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-11-02T13:58:18Z
database_cross_reference: VFB:FBbt_00051964
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051964

Axiom
annotated source: adult efferent neuron
annotated property: definition
annotated target: Any efferent neuron of the adult.
database_cross_reference: FBC:Autogenerated

larval efferent neuron
type: Class
equivalent class: Class
  intersection of: efferent neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: efferent neuron
subclass of: larval CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of larval central nervous system
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: larval central nervous system
definition: Any efferent neuron of the larva.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-11-02T13:58:47Z
database_cross_reference: VFB:FBbt_00051965
has OBO namespace: fly_anatomy.ontology
id: FBbt:00051965

Axiom
annotated source: larval efferent neuron
annotated property: definition
annotated target: Any efferent neuron of the larva.
database_cross_reference: FBC:Autogenerated

cell body rind of larval tritocerebrum
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: larval tritocerebrum
subclass of: Restriction
  on property: part of
  some values from: cell body rind of larval brain
definition: Region of the larval cell body rind that overlies the neuropil of the larval tritocerebrum.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2021-11-23T16:43:16Z
database_cross_reference: VFB:FBbt_00052006
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052006

Axiom
annotated source: cell body rind of larval tritocerebrum
annotated property: definition
annotated target: Region of the larval cell body rind that overlies the neuropil of the larval tritocerebrum.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

adult interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: interneuron
subclass of: adult CNS neuron
subclass of: Restriction
  on property: part of
  some values from: adult central nervous system
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult central nervous system
definition: Any interneuron of the adult.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-01-13T15:30:40Z
database_cross_reference: VFB:FBbt_00052046
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052046

Axiom
annotated source: adult interneuron
annotated property: definition
annotated target: Any interneuron of the adult.
database_cross_reference: FBC:Autogenerated

larval interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: interneuron
subclass of: larval CNS neuron
subclass of: Restriction
  on property: part of
  some values from: larval central nervous system
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of larval central nervous system
definition: Any interneuron of the larva.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-01-13T15:32:23Z
database_cross_reference: VFB:FBbt_00052047
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052047

Axiom
annotated source: larval interneuron
annotated property: definition
annotated target: Any interneuron of the larva.
database_cross_reference: FBC:Autogenerated

cell body rind of adult protocerebrum
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: adult brain cell body rind
subclass of: Restriction
  on property: part of
  some values from: adult protocerebrum
definition: Region of the adult brain cell body rind that overlies the protocerebrum.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-01-14T10:22:56Z
database_cross_reference: VFB:FBbt_00052048
has exact synonym: cortex of adult protocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052048

Axiom
annotated source: cell body rind of adult protocerebrum
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the protocerebrum.
database_cross_reference: FlyBase:FBrf0224194

cell body rind of adult tritocerebrum
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: adult brain cell body rind
subclass of: Restriction
  on property: part of
  some values from: adult tritocerebrum
definition: Region of the adult brain cell body rind that overlies the neuropil of the tritocerebrum.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-01-14T10:41:58Z
database_cross_reference: VFB:FBbt_00052049
has exact synonym: cortex of adult tritocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052049

Axiom
annotated source: cell body rind of adult tritocerebrum
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the neuropil of the tritocerebrum.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

cell body rind of larval deutocerebrum
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: larval deutocerebrum
subclass of: Restriction
  on property: part of
  some values from: cell body rind of larval brain
definition: Region of the larval cell body rind that overlies the neuropil of the larval deutocerebrum.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-01-14T10:45:19Z
database_cross_reference: VFB:FBbt_00052050
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052050

Axiom
annotated source: cell body rind of larval deutocerebrum
annotated property: definition
annotated target: Region of the larval cell body rind that overlies the neuropil of the larval deutocerebrum.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

cell body rind of larval protocerebrum
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: larval protocerebrum
subclass of: Restriction
  on property: part of
  some values from: cell body rind of larval brain
definition: Region of the larval cell body rind that overlies the neuropil of the larval protocerebrum.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-01-14T10:45:44Z
database_cross_reference: VFB:FBbt_00052051
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052051

Axiom
annotated source: cell body rind of larval protocerebrum
annotated property: definition
annotated target: Region of the larval cell body rind that overlies the neuropil of the larval protocerebrum.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

yellow optic column
type: Class
subclass of: optic column
subclass of: Restriction
  on property: overlaps
  some values from: plexiform medulla
subclass of: Restriction
  on property: overlaps
  some values from: plexiform lamina
definition: Optic column that maps to a single yellow ommatidium.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-03-10T15:22:46Z
database_cross_reference: VFB:FBbt_00052134
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052134

Axiom
annotated source: yellow optic column
annotated property: definition
annotated target: Optic column that maps to a single yellow ommatidium.
database_cross_reference: FlyBase:FBrf0252485

pale optic column
type: Class
subclass of: optic column
subclass of: Restriction
  on property: overlaps
  some values from: plexiform medulla
subclass of: Restriction
  on property: overlaps
  some values from: plexiform lamina
definition: Optic column that maps to a single pale ommatidium.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-03-10T15:26:27Z
database_cross_reference: VFB:FBbt_00052135
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052135

Axiom
annotated source: pale optic column
annotated property: definition
annotated target: Optic column that maps to a single pale ommatidium.
database_cross_reference: FlyBase:FBrf0252485

medulla tangential visual projection neuron
type: Class
equivalent class: Class
  intersection of: medulla tangential neuron
  intersection of: visual projection neuron
subclass of: medulla tangential neuron
subclass of: adult visual projection neuron
IAO_0000028: Mt-VPN
definition: Visual projection neuron that has tangential arborization in the medulla (Kind et al., 2021).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-03-21T15:36:10Z
database_cross_reference: VFB:FBbt_00052140
has exact synonym: Mt-VPN
has exact synonym: medulla tangential VPN
has exact synonym: medullary tangential visual projection neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052140

Axiom
annotated source: medulla tangential visual projection neuron
annotated property: IAO_0000028
annotated target: Mt-VPN
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: medulla tangential visual projection neuron
annotated property: definition
annotated target: Visual projection neuron that has tangential arborization in the medulla (Kind et al., 2021).
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: medulla tangential visual projection neuron
annotated property: hasExactSynonym
annotated target: Mt-VPN
database_cross_reference: FlyBase:FBrf0252485
has synonym type: VFB SYMBOL

medulla tangential intrinsic neuron
type: Class
equivalent class: Class
  intersection of: optic lobe tangential neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: medulla
subclass of: adult optic lobe neuron
subclass of: medulla tangential neuron
subclass of: medulla intrinsic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
IAO_0000028: Mti
definition: Intrinsic neuron of the medulla that has a tangential arborization pattern (Kind et al., 2021).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-03-21T16:12:15Z
database_cross_reference: VFB:FBbt_00052142
has exact synonym: Mti
has exact synonym: medullary tangential intrinsic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052142

Axiom
annotated source: medulla tangential intrinsic neuron
annotated property: IAO_0000028
annotated target: Mti
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: medulla tangential intrinsic neuron
annotated property: definition
annotated target: Intrinsic neuron of the medulla that has a tangential arborization pattern (Kind et al., 2021).
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: medulla tangential intrinsic neuron
annotated property: hasExactSynonym
annotated target: Mti
database_cross_reference: FlyBase:FBrf0252485
has synonym type: VFB SYMBOL

gut-innervating neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: overlaps
    some values from: gut
subclass of: neuron
subclass of: Restriction
  on property: overlaps
  some values from: gut
definition: Neuron that innervates any part of the gut. These cells include sensory neurons, as well as efferent neurons that terminate on the visceral muscles and the underlying epithelium (Lemaitre and Miguel-Aliaga, 2013). They are chemically and neuroanatomically diverse, with efferent neurons collectively producing several neuropeptides and serotonin (Lemaitre and Miguel-Aliaga, 2013).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-03-24T13:50:11Z
database_cross_reference: VFB:FBbt_00052149
has narrow synonym: enteric neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052149
comment: Many recent papers do not count the pharyngeal and labral taste neurons as 'enteric neurons', hence only a narrow synonym.

Axiom
annotated source: gut-innervating neuron
annotated property: definition
annotated target: Neuron that innervates any part of the gut. These cells include sensory neurons, as well as efferent neurons that terminate on the visceral muscles and the underlying epithelium (Lemaitre and Miguel-Aliaga, 2013). They are chemically and neuroanatomically diverse, with efferent neurons collectively producing several neuropeptides and serotonin (Lemaitre and Miguel-Aliaga, 2013).
database_cross_reference: FlyBase:FBrf0223413

adult gut-innervating neuron
type: Class
equivalent class: Class
  intersection of: gut-innervating neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult neuron
subclass of: gut-innervating neuron
subclass of: Restriction
  on property: overlaps
  some values from: adult gut
definition: Any gut-innervating neuron of the adult.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-03-24T14:13:41Z
database_cross_reference: VFB:FBbt_00052150
has narrow synonym: adult enteric neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052150
comment: Many recent papers do not count the pharyngeal and labral taste neurons as 'enteric neurons', hence only a narrow synonym.

Axiom
annotated source: adult gut-innervating neuron
annotated property: definition
annotated target: Any gut-innervating neuron of the adult.
database_cross_reference: FlyBase:FBrf0223413

larval gut-innervating neuron
type: Class
equivalent class: Class
  intersection of: gut-innervating neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuron
subclass of: gut-innervating neuron
subclass of: Restriction
  on property: overlaps
  some values from: embryonic/larval gut
definition: Any gut-innervating neuron of the larva.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-03-24T14:16:12Z
database_cross_reference: VFB:FBbt_00052151
has narrow synonym: larval enteric neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052151

Axiom
annotated source: larval gut-innervating neuron
annotated property: definition
annotated target: Any gut-innervating neuron of the larva.
database_cross_reference: FlyBase:FBrf0223413

larval superior protocerebrum
type: Class
subclass of: synaptic neuropil block
subclass of: Restriction
  on property: part of
  some values from: larval protocerebrum
definition: Dorsalmost layer of larval synaptic neuropil domains, found dorsal to the inferior protocerebrum (Hartenstein et al., 2015).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-06-16T15:02:21Z
database_cross_reference: VFB:FBbt_00052193
database_cross_reference: larvalbrain_neuropil:410
database_cross_reference: larvalbrain_neuropil:588
has exact synonym: larval SP
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052193

Axiom
annotated source: larval superior protocerebrum
annotated property: definition
annotated target: Dorsalmost layer of larval synaptic neuropil domains, found dorsal to the inferior protocerebrum (Hartenstein et al., 2015).
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: larval superior protocerebrum
annotated property: hasExactSynonym
annotated target: larval SP
database_cross_reference: FlyBase:FBrf0229672

immature T4 neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T4 neuron
subclass of: immature secondary neuron
subclass of: immature T neuron
subclass of: Restriction
  on property: develops from
  some values from: type III neuroblast
subclass of: Restriction
  on property: develops into
  some values from: T4 neuron
definition: Immature secondary neuron that is a precursor to an adult T4 neuron (Hormann et al., 2020). It is generated from a neuroblast that amplifies by symmetric division (type III) before generating the T4 (and T5) neurons (Mora et al., 2018). During its development, it first projects its axon to the appropriate lobula plate layer, then forms its dendrites in medulla layer 10 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T09:49:06Z
database_cross_reference: VFB:FBbt_00052257
has exact synonym: developing T4 neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052257

Axiom
annotated source: immature T4 neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T4 neuron (Hormann et al., 2020). It is generated from a neuroblast that amplifies by symmetric division (type III) before generating the T4 (and T5) neurons (Mora et al., 2018). During its development, it first projects its axon to the appropriate lobula plate layer, then forms its dendrites in medulla layer 10 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0238554
database_cross_reference: FlyBase:FBrf0245647

immature T5 neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T5 neuron
subclass of: immature secondary neuron
subclass of: immature T neuron
subclass of: Restriction
  on property: develops from
  some values from: type III neuroblast
subclass of: Restriction
  on property: develops into
  some values from: T5 neuron
definition: Immature secondary neuron that is a precursor to an adult T5 neuron (Hormann et al., 2020). It is generated from a neuroblast that amplifies by symmetric division (type III) before generating the T5 (and T4) neurons (Mora et al., 2018). During its development, it first projects its axon to the appropriate lobula plate layer, then forms its dendrites in lobula layer 1 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T09:56:10Z
database_cross_reference: VFB:FBbt_00052258
has exact synonym: developing T5 neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052258

Axiom
annotated source: immature T5 neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T5 neuron (Hormann et al., 2020). It is generated from a neuroblast that amplifies by symmetric division (type III) before generating the T5 (and T4) neurons (Mora et al., 2018). During its development, it first projects its axon to the appropriate lobula plate layer, then forms its dendrites in lobula layer 1 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0238554
database_cross_reference: FlyBase:FBrf0245647

immature T5a neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T5a neuron
subclass of: immature T5 neuron
subclass of: Restriction
  on property: develops into
  some values from: T5a neuron
definition: Immature secondary neuron that is a precursor to an adult T5a neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 1 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T10:07:13Z
database_cross_reference: VFB:FBbt_00052259
has exact synonym: developing T5a neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052259

Axiom
annotated source: immature T5a neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T5a neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 1 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

immature T5b neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T5b neuron
subclass of: immature T5 neuron
subclass of: Restriction
  on property: develops into
  some values from: T5b neuron
definition: Immature secondary neuron that is a precursor to an adult T5b neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 2 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T10:09:37Z
database_cross_reference: VFB:FBbt_00052260
has exact synonym: developing T5b neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052260

Axiom
annotated source: immature T5b neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T5b neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 2 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

immature T5c neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T5c neuron
subclass of: immature T5 neuron
subclass of: Restriction
  on property: develops into
  some values from: T5c neuron
definition: Immature secondary neuron that is a precursor to an adult T5c neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 3 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T10:10:06Z
database_cross_reference: VFB:FBbt_00052261
has exact synonym: developing T5c neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052261

Axiom
annotated source: immature T5c neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T5c neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 3 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

immature T5d neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T5d neuron
subclass of: immature T5 neuron
subclass of: Restriction
  on property: develops into
  some values from: T5d neuron
definition: Immature secondary neuron that is a precursor to an adult T5d neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 4 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T10:10:20Z
database_cross_reference: VFB:FBbt_00052262
has exact synonym: developing T5d neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052262

Axiom
annotated source: immature T5d neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T5d neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 4 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

immature T4a neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T4a neuron
subclass of: immature T4 neuron
subclass of: Restriction
  on property: develops into
  some values from: T4a neuron
definition: Immature secondary neuron that is a precursor to an adult T4a neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 1 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T10:10:39Z
database_cross_reference: VFB:FBbt_00052263
has exact synonym: developing T4a neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052263

Axiom
annotated source: immature T4a neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T4a neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 1 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

immature T4b neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T4b neuron
subclass of: immature T4 neuron
subclass of: Restriction
  on property: develops into
  some values from: T4b neuron
definition: Immature secondary neuron that is a precursor to an adult T4b neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 2 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T10:11:44Z
database_cross_reference: VFB:FBbt_00052264
has exact synonym: developing T4b neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052264

Axiom
annotated source: immature T4b neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T4b neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 2 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

immature T4c neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T4c neuron
subclass of: immature T4 neuron
subclass of: Restriction
  on property: develops into
  some values from: T4c neuron
definition: Immature secondary neuron that is a precursor to an adult T4c neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 3 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T10:12:37Z
database_cross_reference: VFB:FBbt_00052265
has exact synonym: developing T4c neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052265

Axiom
annotated source: immature T4c neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T4c neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 3 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

immature T4d neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T4d neuron
subclass of: immature T4 neuron
subclass of: Restriction
  on property: develops into
  some values from: T4d neuron
definition: Immature secondary neuron that is a precursor to an adult T4d neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 4 (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-08-05T10:13:17Z
database_cross_reference: VFB:FBbt_00052266
has exact synonym: developing T4d neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052266

Axiom
annotated source: immature T4d neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T4d neuron (Hormann et al., 2020). Early during its development, it projects its axon to lobula plate layer 4 (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

immature distal medullary amacrine neuron Dm1
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm1
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm1
definition: Immature form of the distal medullary amacrine neuron Dm1 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052305
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052305

Axiom
annotated source: immature distal medullary amacrine neuron Dm1
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm1 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature distal medullary amacrine neuron Dm10
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm10
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm10
definition: Immature form of the distal medullary amacrine neuron Dm10 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Ey/Hbn temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052306
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052306

Axiom
annotated source: immature distal medullary amacrine neuron Dm10
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm10 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Ey/Hbn temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature distal medullary amacrine neuron Dm11
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm11
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm11
definition: Immature form of the distal medullary amacrine neuron Dm11 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052307
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052307

Axiom
annotated source: immature distal medullary amacrine neuron Dm11
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm11 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature distal medullary amacrine neuron Dm12
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm12
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm12
definition: Immature form of the distal medullary amacrine neuron Dm12 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052308
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052308

Axiom
annotated source: immature distal medullary amacrine neuron Dm12
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm12 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature distal medullary amacrine neuron Dm2
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm2
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm2
definition: Immature form of the distal medullary amacrine neuron Dm2 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the D/BarHI temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052309
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052309

Axiom
annotated source: immature distal medullary amacrine neuron Dm2
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm2 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the D/BarHI temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature distal medullary amacrine neuron Dm3
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm3
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm3
definition: Immature form of the distal medullary amacrine neuron Dm3 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Slp/D temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052310
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052310

Axiom
annotated source: immature distal medullary amacrine neuron Dm3
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm3 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Slp/D temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature distal medullary amacrine neuron Dm4
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm4
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm4
definition: Immature form of the distal medullary amacrine neuron Dm4 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052313
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052313

Axiom
annotated source: immature distal medullary amacrine neuron Dm4
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm4 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature distal medullary amacrine neuron Dm8a
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm8a
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm8a
definition: Immature form of the distal medullary amacrine neuron Dm8a (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052314
has exact synonym: immature distal medullary amacrine neuron Dm8
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052314

Axiom
annotated source: immature distal medullary amacrine neuron Dm8a
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm8a (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature distal medullary amacrine neuron Dm9
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron Dm9
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature distal medullary amacrine neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron Dm9
definition: Immature form of the distal medullary amacrine neuron Dm9 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052315
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052315

Axiom
annotated source: immature distal medullary amacrine neuron Dm9
annotated property: definition
annotated target: Immature form of the distal medullary amacrine neuron Dm9 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature lamina intrinsic neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: lamina intrinsic neuron Lai
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: lamina intrinsic neuron Lai
definition: Immature form of the lamina intrinsic neuron (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052316
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052316

Axiom
annotated source: immature lamina intrinsic neuron
annotated property: definition
annotated target: Immature form of the lamina intrinsic neuron (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature medulla intrinsic neuron Mi1
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: medulla intrinsic neuron Mi1
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: medulla intrinsic neuron Mi1
definition: Immature form of the medullary intrinsic neuron Mi1 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052317
has exact synonym: immature medullary intrinsic neuron Mi1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052317

Axiom
annotated source: immature medulla intrinsic neuron Mi1
annotated property: definition
annotated target: Immature form of the medullary intrinsic neuron Mi1 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature medulla intrinsic neuron Mi15
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: medulla intrinsic neuron Mi15
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature dopaminergic neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: medulla intrinsic neuron Mi15
definition: Immature form of the medullary intrinsic neuron Mi15 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the D/BarHI temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052318
has exact synonym: immature medullary intrinsic neuron Mi15
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052318

Axiom
annotated source: immature medulla intrinsic neuron Mi15
annotated property: definition
annotated target: Immature form of the medullary intrinsic neuron Mi15 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the D/BarHI temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature medulla intrinsic neuron Mi4
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: medulla intrinsic neuron Mi4
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: medulla intrinsic neuron Mi4
definition: Immature form of the medullary intrinsic neuron Mi4 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052319
has exact synonym: immature medullary intrinsic neuron Mi4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052319

Axiom
annotated source: immature medulla intrinsic neuron Mi4
annotated property: definition
annotated target: Immature form of the medullary intrinsic neuron Mi4 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature medulla intrinsic neuron Mi9
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: medulla intrinsic neuron Mi9
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: medulla intrinsic neuron Mi9
definition: Immature form of the medullary intrinsic neuron Mi9 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Opa/Erm temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052320
has exact synonym: immature medullary intrinsic neuron Mi9
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052320

Axiom
annotated source: immature medulla intrinsic neuron Mi9
annotated property: definition
annotated target: Immature form of the medullary intrinsic neuron Mi9 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Opa/Erm temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature proximal medullary amacrine neuron Pm4
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: proximal medullary amacrine neuron Pm4
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: proximal medullary amacrine neuron Pm4
definition: Immature form of the proximal medullary amacrine neuron Pm4 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052323
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052323

Axiom
annotated source: immature proximal medullary amacrine neuron Pm4
annotated property: definition
annotated target: Immature form of the proximal medullary amacrine neuron Pm4 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature columnar neuron T1
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: columnar neuron T1
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: columnar neuron T1
definition: Immature form of the columnar neuron T1 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the D/BarHI temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052324
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052324

Axiom
annotated source: immature columnar neuron T1
annotated property: definition
annotated target: Immature form of the columnar neuron T1 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the D/BarHI temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm1
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm1
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm1
definition: Immature form of the transmedullary neuron Tm1 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052325
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052325

Axiom
annotated source: immature transmedullary neuron Tm1
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm1 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm2
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm2
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm2
definition: Immature form of the transmedullary neuron Tm2 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052326
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052326

Axiom
annotated source: immature transmedullary neuron Tm2
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm2 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm20
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm20
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm20
definition: Immature form of the transmedullary neuron Tm20 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052327
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052327

Axiom
annotated source: immature transmedullary neuron Tm20
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm20 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm29
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm29
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm29
definition: Immature form of the transmedullary neuron Tm29 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052328
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052328

Axiom
annotated source: immature transmedullary neuron Tm29
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm29 (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm3
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm3
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm3
definition: Immature form of the transmedullary neuron Tm3 (Tm3a) (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052329
has exact synonym: immature transmedullary neuron Tm3a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052329

Axiom
annotated source: immature transmedullary neuron Tm3
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm3 (Tm3a) (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm4
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm4
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm4
definition: Immature form of the transmedullary neuron Tm4 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052330
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052330

Axiom
annotated source: immature transmedullary neuron Tm4
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm4 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth/Opa temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm5b
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm5b
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm5b
definition: Immature form of the transmedullary neuron Tm5b (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052331
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052331

Axiom
annotated source: immature transmedullary neuron Tm5b
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm5b (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Hbn/Opa/Slp temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm5c
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm5c
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm5c
definition: Immature form of the transmedullary neuron Tm5c (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Opa/Erm temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052332
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052332

Axiom
annotated source: immature transmedullary neuron Tm5c
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm5c (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Opa/Erm temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm9
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm9
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm9
definition: Immature form of the transmedullary neuron Tm9 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052333
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052333

Axiom
annotated source: immature transmedullary neuron Tm9
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm9 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm9a
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm9a
subclass of: immature transmedullary neuron Tm9
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm9a
definition: Immature form of the transmedullary neuron Tm9a (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052334
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052334

Axiom
annotated source: immature transmedullary neuron Tm9a
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm9a (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron Tm9b
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron Tm9b
subclass of: immature transmedullary neuron Tm9
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron Tm9b
definition: Immature form of the transmedullary neuron Tm9b (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052335
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052335

Axiom
annotated source: immature transmedullary neuron Tm9b
annotated property: definition
annotated target: Immature form of the transmedullary neuron Tm9b (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary Y neuron TmY3
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary Y neuron TmY3
subclass of: Notch ON hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary Y neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary Y neuron TmY3
definition: Immature form of the transmedullary Y neuron TmY3 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052337
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052337

Axiom
annotated source: immature transmedullary Y neuron TmY3
annotated property: definition
annotated target: Immature form of the transmedullary Y neuron TmY3 (Konstantinides et al., 2022). It is a Notch ON hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary Y neuron TmY5a
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary Y neuron TmY5a
subclass of: Notch OFF hemilineage secondary neuron
subclass of: immature secondary neuron
subclass of: immature transmedullary Y neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: transmedullary Y neuron TmY5a
definition: Immature form of the transmedullary Y neuron TmY5a (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-29T14:00:00Z
database_cross_reference: VFB:FBbt_00052339
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052339

Axiom
annotated source: immature transmedullary Y neuron TmY5a
annotated property: definition
annotated target: Immature form of the transmedullary Y neuron TmY5a (Konstantinides et al., 2022). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Erm/Ey temporal window (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

optic neuroblast
type: Class
subclass of: protocerebral neuroblast
subclass of: larval neuroblast
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: optic lobe neuroepithelial cell
definition: Neuroblast that generates neurons of the optic lobe. It arises from the optic lobe neuroepithelium, with some delaminating during the embryonic stage and others delaminating during the larval stage (Hakes et al., 2018).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-09-30T16:24:12Z
database_cross_reference: VFB:FBbt_00052344
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052344

Axiom
annotated source: optic neuroblast
annotated property: definition
annotated target: Neuroblast that generates neurons of the optic lobe. It arises from the optic lobe neuroepithelium, with some delaminating during the embryonic stage and others delaminating during the larval stage (Hakes et al., 2018).
database_cross_reference: FlyBase:FBrf0240123

larval neuropil glial sheath
type: Class
equivalent class: Class
  intersection of: neuropil glial sheath
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: neuropil glial sheath
subclass of: Restriction
  on property: part of
  some values from: larval central nervous system
definition: Any neuropil glial sheath of the larva.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-10-26T11:01:04Z
database_cross_reference: VFB:FBbt_00052367
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052367

Axiom
annotated source: larval neuropil glial sheath
annotated property: definition
annotated target: Any neuropil glial sheath of the larva.
database_cross_reference: FBC:Autogenerated

adult neuropil glial sheath
type: Class
equivalent class: Class
  intersection of: neuropil glial sheath
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: neuropil glial sheath
subclass of: Restriction
  on property: part of
  some values from: adult central nervous system
definition: Any neuropil glial sheath of the adult.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-10-26T10:59:20Z
database_cross_reference: VFB:FBbt_00052368
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052368

Axiom
annotated source: adult neuropil glial sheath
annotated property: definition
annotated target: Any neuropil glial sheath of the adult.
database_cross_reference: FBC:Autogenerated

larval brain ensheathing glial cell
type: Class
equivalent class: Class
  intersection of: ensheathing glial cell
  intersection of: Restriction
    on property: part of
    some values from: larval brain
subclass of: embryonic/larval ensheathing glial cell
subclass of: larval brain neuropil glial cell
definition: Ensheathing glial cell of the larval brain. There are approximately 12 of these cells in each brain hemisphere throughout larval development (Omoto et al., 2015).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-10-27T10:37:47Z
database_cross_reference: VFB:FBbt_00052370
has exact synonym: embryonic/larval brain ensheathing neuropil associated glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052370

Axiom
annotated source: larval brain ensheathing glial cell
annotated property: definition
annotated target: Ensheathing glial cell of the larval brain. There are approximately 12 of these cells in each brain hemisphere throughout larval development (Omoto et al., 2015).
database_cross_reference: FlyBase:FBrf0229106

adult primary neuropil glial cell
type: Class
equivalent class: Class
  intersection of: adult neuropil glial cell
  intersection of: Restriction
    on property: develops from
    some values from: larval neuropil glial cell
subclass of: adult neuropil glial cell
subclass of: Restriction
  on property: develops from
  some values from: embryonic/larval ensheathing glial cell
definition: Neuropil glial cell of the adult that is derived from a larval glial cell (Kato et al., 2020). The larval astrocyte-like glia die during the pupal phase, while some of the ensheathing glia persist and divide to generate these cells (Kato et al., 2020). In the brain, these cells tend to occupy an anterior-inferior area (Kato et al., 2020).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2022-10-28T09:39:02Z
database_cross_reference: VFB:FBbt_00052378
has exact synonym: adult L-EG
has exact synonym: adult pNG
has exact synonym: adult primary neuropil associated glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052378

Axiom
annotated source: adult primary neuropil glial cell
annotated property: definition
annotated target: Neuropil glial cell of the adult that is derived from a larval glial cell (Kato et al., 2020). The larval astrocyte-like glia die during the pupal phase, while some of the ensheathing glia persist and divide to generate these cells (Kato et al., 2020). In the brain, these cells tend to occupy an anterior-inferior area (Kato et al., 2020).
database_cross_reference: FlyBase:FBrf0245107

Axiom
annotated source: adult primary neuropil glial cell
annotated property: hasExactSynonym
annotated target: adult L-EG
database_cross_reference: FlyBase:FBrf0245107

peripheral sensory precursor cell
type: Class
subclass of: somatic precursor cell
definition: Precursor cell that can give rise to one or more sensory neurons and/or support cells of the periphery.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-01-24T15:23:51Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052556

Axiom
annotated source: peripheral sensory precursor cell
annotated property: definition
annotated target: Precursor cell that can give rise to one or more sensory neurons and/or support cells of the periphery.
database_cross_reference: FlyBase:FBrf0055951
database_cross_reference: FlyBase:FBrf0083795
database_cross_reference: FlyBase:FBrf0132424

LC4 optic glomerulus
type: Class
subclass of: optic glomerulus of the PVLP
subclass of: Restriction
  on property: receives input from
  some values from: lobula columnar neuron LC4
definition: Optic glomerulus formed by the axon terminals of lobula columnar (LC) 4 neurons (Wu et al., 2016). It is found in the ventral medial part of the posterior ventrolateral protocerebrum ventral to the LPLC1 and LPLC2 glomeruli (Wu et al., 2016). LC4 axon terminals retain anterior-posterior topography in this glomerulus (Dombrovski et al., 2023).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-10-16T13:37:16Z
database_cross_reference: VFB:FBbt_00052655
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052655

Axiom
annotated source: LC4 optic glomerulus
annotated property: definition
annotated target: Optic glomerulus formed by the axon terminals of lobula columnar (LC) 4 neurons (Wu et al., 2016). It is found in the ventral medial part of the posterior ventrolateral protocerebrum ventral to the LPLC1 and LPLC2 glomeruli (Wu et al., 2016). LC4 axon terminals retain anterior-posterior topography in this glomerulus (Dombrovski et al., 2023).
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0255530

LPLC2 optic glomerulus
type: Class
subclass of: optic glomerulus of the PVLP
subclass of: Restriction
  on property: receives input from
  some values from: lobula plate-lobula columnar neuron LPLC2
definition: Optic glomerulus formed by the axon terminals of lobula plate-lobula columnar (LPLC) 2 neurons (Wu et al., 2016). It is found in the ventral part of the posterior ventrolateral protocerebrum (Wu et al., 2016). It does not display retinotopic organization (Dombrovski et al., 2023).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-10-16T13:47:53Z
database_cross_reference: VFB:FBbt_00052656
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052656

Axiom
annotated source: LPLC2 optic glomerulus
annotated property: definition
annotated target: Optic glomerulus formed by the axon terminals of lobula plate-lobula columnar (LPLC) 2 neurons (Wu et al., 2016). It is found in the ventral part of the posterior ventrolateral protocerebrum (Wu et al., 2016). It does not display retinotopic organization (Dombrovski et al., 2023).
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0255530

LPLC1 optic glomerulus
type: Class
subclass of: optic glomerulus of the PVLP
subclass of: Restriction
  on property: receives input from
  some values from: lobula plate-lobula columnar neuron LPLC1
definition: Optic glomerulus formed by the axon terminals of lobula plate-lobula columnar (LPLC) 1 neurons (Wu et al., 2016). It the most posterior glomerulus in the ventral part of the posterior ventrolateral protocerebrum, close to the boundary with the posterior lateral protocerebrum (Wu et al., 2016). It retains rough anterior-posterior organization of LPLC1 axon terminals (Dombrovski et al., 2023).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-10-16T13:51:29Z
database_cross_reference: VFB:FBbt_00052657
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052657

Axiom
annotated source: LPLC1 optic glomerulus
annotated property: definition
annotated target: Optic glomerulus formed by the axon terminals of lobula plate-lobula columnar (LPLC) 1 neurons (Wu et al., 2016). It the most posterior glomerulus in the ventral part of the posterior ventrolateral protocerebrum, close to the boundary with the posterior lateral protocerebrum (Wu et al., 2016). It retains rough anterior-posterior organization of LPLC1 axon terminals (Dombrovski et al., 2023).
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0255530

immature secondary neuron
type: Class
equivalent class: Class
  intersection of: secondary neuron
  intersection of: immature neuron
subclass of: secondary neuron
subclass of: immature neuron
definition: Secondary neuron, born after the embryonic stage, that is still in an immature state, between birth and its first mature morphology.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2023-10-17T14:34:00Z
database_cross_reference: VFB:FBbt_00052664
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052664

Axiom
annotated source: immature secondary neuron
annotated property: definition
annotated target: Secondary neuron, born after the embryonic stage, that is still in an immature state, between birth and its first mature morphology.
database_cross_reference: FlyBase:FBrf0253187

adult neuromere
type: Class
equivalent class: Class
  intersection of: neuromere
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: neuromere
subclass of: Class
  intersection of: Restriction
    on property: part of
    some values from: adult segment
  intersection of: Restriction
    on property: part of
    some values from: adult central nervous system
definition: Any neuromere of the adult.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2024-01-12T15:15:54Z
database_cross_reference: VFB:FBbt_00052718
has OBO namespace: fly_anatomy.ontology
id: FBbt:00052718

Axiom
annotated source: adult neuromere
annotated property: definition
annotated target: Any neuromere of the adult.
database_cross_reference: FBC:Autogenerated

immature distal medullary amacrine neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: distal medullary amacrine neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops into
  some values from: distal medullary amacrine neuron
definition: Immature form of a distal medullary amacrine neuron (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2024-06-12T14:21:40Z
database_cross_reference: VFB:FBbt_00053272
has exact synonym: immature Dm neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053272

Axiom
annotated source: immature distal medullary amacrine neuron
annotated property: definition
annotated target: Immature form of a distal medullary amacrine neuron (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature lobula columnar neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: lobula columnar neuron
subclass of: immature neuron
subclass of: Restriction
  on property: develops into
  some values from: lobula columnar neuron
definition: Immature form of a lobula columnar neuron (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2024-06-12T14:21:50Z
database_cross_reference: VFB:FBbt_00053273
has exact synonym: immature LC neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053273

Axiom
annotated source: immature lobula columnar neuron
annotated property: definition
annotated target: Immature form of a lobula columnar neuron (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature transmedullary neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops into
  some values from: transmedullary neuron
definition: Immature form of a transmedullary neuron (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2024-06-12T14:21:56Z
database_cross_reference: VFB:FBbt_00053274
has exact synonym: immature Tm neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053274

Axiom
annotated source: immature transmedullary neuron
annotated property: definition
annotated target: Immature form of a transmedullary neuron (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature optic lobe centrifugal columnar neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: optic lobe centrifugal columnar neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops into
  some values from: optic lobe centrifugal columnar neuron
definition: Immature form of a centrifugal columnar neuron (Konstantinides et al., 2022).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2024-06-12T14:22:02Z
database_cross_reference: VFB:FBbt_00053275
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053275

Axiom
annotated source: immature optic lobe centrifugal columnar neuron
annotated property: definition
annotated target: Immature form of a centrifugal columnar neuron (Konstantinides et al., 2022).
database_cross_reference: FlyBase:FBrf0253187

immature lamina monopolar neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: lamina monopolar neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops into
  some values from: lamina monopolar neuron
definition: Immature neuron that will develop into an adult lamina monopolar neuron.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-01-28T17:12:59Z
database_cross_reference: VFB:FBbt_00053355
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053355

Axiom
annotated source: immature lamina monopolar neuron
annotated property: definition
annotated target: Immature neuron that will develop into an adult lamina monopolar neuron.
database_cross_reference: FlyBase:FBrf0243031

immature lamina monopolar neuron L1
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: lamina monopolar neuron L1
subclass of: immature lamina monopolar neuron
subclass of: Restriction
  on property: develops into
  some values from: lamina monopolar neuron L1
definition: Immature neuron that will develop into an adult lamina monopolar neuron L1.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-01-28T17:15:19Z
database_cross_reference: VFB:FBbt_00053356
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053356

Axiom
annotated source: immature lamina monopolar neuron L1
annotated property: definition
annotated target: Immature neuron that will develop into an adult lamina monopolar neuron L1.
database_cross_reference: FlyBase:FBrf0243031

immature lamina monopolar neuron L2
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: lamina monopolar neuron L2
subclass of: immature lamina monopolar neuron
subclass of: Restriction
  on property: develops into
  some values from: lamina monopolar neuron L2
definition: Immature neuron that will develop into an adult lamina monopolar neuron L2.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-01-28T17:15:27Z
database_cross_reference: VFB:FBbt_00053357
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053357

Axiom
annotated source: immature lamina monopolar neuron L2
annotated property: definition
annotated target: Immature neuron that will develop into an adult lamina monopolar neuron L2.
database_cross_reference: FlyBase:FBrf0243031

immature lamina monopolar neuron L3
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: lamina monopolar neuron L3
subclass of: immature lamina monopolar neuron
subclass of: Restriction
  on property: develops into
  some values from: lamina monopolar neuron L3
definition: Immature neuron that will develop into an adult lamina monopolar neuron L3.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-01-28T17:15:33Z
database_cross_reference: VFB:FBbt_00053358
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053358

Axiom
annotated source: immature lamina monopolar neuron L3
annotated property: definition
annotated target: Immature neuron that will develop into an adult lamina monopolar neuron L3.
database_cross_reference: FlyBase:FBrf0243031

immature lamina monopolar neuron L4
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: lamina monopolar neuron L4
subclass of: immature lamina monopolar neuron
subclass of: Restriction
  on property: develops into
  some values from: lamina monopolar neuron L4
definition: Immature neuron that will develop into an adult lamina monopolar neuron L4.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-01-28T17:15:39Z
database_cross_reference: VFB:FBbt_00053359
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053359

Axiom
annotated source: immature lamina monopolar neuron L4
annotated property: definition
annotated target: Immature neuron that will develop into an adult lamina monopolar neuron L4.
database_cross_reference: FlyBase:FBrf0243031

immature lamina monopolar neuron L5
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: lamina monopolar neuron L5
subclass of: immature lamina monopolar neuron
subclass of: Restriction
  on property: develops into
  some values from: lamina monopolar neuron L5
definition: Immature neuron that will develop into an adult lamina monopolar neuron L5.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-01-28T17:15:44Z
database_cross_reference: VFB:FBbt_00053360
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053360

Axiom
annotated source: immature lamina monopolar neuron L5
annotated property: definition
annotated target: Immature neuron that will develop into an adult lamina monopolar neuron L5.
database_cross_reference: FlyBase:FBrf0243031

adult primary visual center
type: Class
subclass of: material anatomical entity
subclass of: Restriction
  on property: part of
  some values from: adult brain
definition: Region of the adult brain that receives photoreceptor input, i.e. the optic lobe or ocellar ganglion.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-03-13T15:24:25Z
database_cross_reference: VFB:FBbt_00053384
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053384

Axiom
annotated source: adult primary visual center
annotated property: definition
annotated target: Region of the adult brain that receives photoreceptor input, i.e. the optic lobe or ocellar ganglion.
database_cross_reference: FlyBase:FBrf0260546

medulla intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: medulla
subclass of: adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: synapses restricted to region
  some values from: medulla
definition: Any neuron with its arborizations exclusively within the medulla (Raghu and Borst, 2011).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-03-13T14:52:57Z
database_cross_reference: VFB:FBbt_00053385
has exact synonym: medullary intrinsic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053385

Axiom
annotated source: medulla intrinsic neuron
annotated property: definition
annotated target: Any neuron with its arborizations exclusively within the medulla (Raghu and Borst, 2011).
database_cross_reference: FlyBase:FBrf0213690

adult subesophageal zone intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: adult subesophageal zone
subclass of: adult central brain intrinsic neuron
subclass of: Restriction
  on property: synapses restricted to region
  some values from: adult subesophageal zone
definition: Any neuron (FBbt:00005106) that synapses restricted to region some adult subesophageal zone (FBbt:00110639).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-03-13T16:11:00Z
database_cross_reference: VFB:FBbt_00053386
has exact synonym: adult SEZ intrinsic neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053386

Axiom
annotated source: adult subesophageal zone intrinsic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that synapses restricted to region some adult subesophageal zone (FBbt:00110639).
database_cross_reference: FBC:Autogenerated

input/output neuron
type: Class
subclass of: interneuron
definition: An interneuron that has distinct dendritic and axonal branches that arborize in different neuropil regions. These neurons relay information between different parts of the central nervous system.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-03-21T10:32:23Z
database_cross_reference: VFB:FBbt_00053396
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053396
comment: Includes neurons with axonal and dendritic arbors in the same region if there is another branch that extends elsewhere (Frechter et al., 2019). Excludes neurons that only have a 'local' innervation pattern, where both inputs/outputs may be present on arbors that span neuropil boundaries.

Axiom
annotated source: input/output neuron
annotated property: definition
annotated target: An interneuron that has distinct dendritic and axonal branches that arborize in different neuropil regions. These neurons relay information between different parts of the central nervous system.
database_cross_reference: FlyBase:FBrf0238440
database_cross_reference: FlyBase:FBrf0242628

immature dopaminergic neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: dopaminergic neuron
subclass of: immature neuron
subclass of: Restriction
  on property: develops into
  some values from: dopaminergic neuron
definition: Immature neuron that will become a dopaminergic neuron, including neurons that are not yet producing dopamine (Hartenstein et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-06-30T14:01:29Z
database_cross_reference: VFB:FBbt_00053522
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053522

Axiom
annotated source: immature dopaminergic neuron
annotated property: definition
annotated target: Immature neuron that will become a dopaminergic neuron, including neurons that are not yet producing dopamine (Hartenstein et al., 2017).
database_cross_reference: FlyBase:FBrf0234128

immature adult optic lobe neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: adult optic lobe neuron
subclass of: anterior ectoderm derivative
subclass of: immature neuron
subclass of: Restriction
  on property: develops from
  some values from: optic neuroblast
subclass of: Restriction
  on property: develops into
  some values from: adult optic lobe neuron
definition: Immature neuron that develops from an optic neuroblast and will become an adult optic lobe neuron.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-07-14T12:37:17Z
database_cross_reference: VFB:FBbt_00053539
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053539

immature adult optic lobe intrinsic neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: adult optic lobe intrinsic neuron
subclass of: immature neuron
subclass of: Restriction
  on property: develops into
  some values from: adult optic lobe intrinsic neuron
definition: Immature neuron that will have its synapses restricted to the optic lobe in the adult.
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-07-14T12:41:54Z
database_cross_reference: VFB:FBbt_00053540
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053540

immature transmedullary Y neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: transmedullary Y neuron
subclass of: immature transmedullary neuron
subclass of: Restriction
  on property: develops into
  some values from: transmedullary Y neuron
definition: Immature transmedullary Y neuron (Ngo et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-07-14T16:39:57Z
database_cross_reference: VFB:FBbt_00053542
has exact synonym: immature TmY neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053542

Axiom
annotated source: immature transmedullary Y neuron
annotated property: definition
annotated target: Immature transmedullary Y neuron (Ngo et al., 2017).
database_cross_reference: FlyBase:FBrf0236058

immature proximal medullary amacrine neuron Pm3
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: proximal medullary amacrine neuron Pm3
subclass of: immature secondary neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops from
  some values from: medulla forming neuroblast
subclass of: Restriction
  on property: develops into
  some values from: proximal medullary amacrine neuron Pm3
definition: Immature form of the proximal medullary amacrine neuron Pm2 (Erclik et al., 2017). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth temporal window (Erclik et al., 2017).
contributor: https://orcid.org/0000-0002-1373-1705
date: 2025-07-15T08:38:26Z
database_cross_reference: VFB:FBbt_00053543
has OBO namespace: fly_anatomy.ontology
id: FBbt:00053543

Axiom
annotated source: immature proximal medullary amacrine neuron Pm3
annotated property: definition
annotated target: Immature form of the proximal medullary amacrine neuron Pm2 (Erclik et al., 2017). It is a Notch OFF hemilineage secondary neuron, born from a medulla forming neuroblast during the Hth temporal window (Erclik et al., 2017).
database_cross_reference: FlyBase:FBrf0234567

anterior-posterior subdivision of organism
type: Class
subclass of: organism subdivision
definition: Division of an organism along its anterior-posterior axis.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2008-06-30T04:15:23Z
database_cross_reference: UBERON:0011676
has OBO namespace: fly_anatomy.ontology
id: FBbt:00057001
in subset: larval OF

Axiom
annotated source: anterior-posterior subdivision of organism
annotated property: definition
annotated target: Division of an organism along its anterior-posterior axis.
database_cross_reference: https://orcid.org/0000-0002-1373-1705

adult aminergic neuron
type: Class
equivalent class: Class
  intersection of: aminergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: aminergic neuron
subclass of: adult neuron
definition: Any aminergic neuron of the adult.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058201
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058201
in subset: cur

Axiom
annotated source: adult aminergic neuron
annotated property: definition
annotated target: Any aminergic neuron of the adult.
database_cross_reference: FBC:Autogenerated

adult cholinergic neuron
type: Class
equivalent class: Class
  intersection of: cholinergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: cholinergic neuron
subclass of: adult neuron
definition: Any cholinergic neuron of the adult.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058205
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058205
in subset: cur

Axiom
annotated source: adult cholinergic neuron
annotated property: definition
annotated target: Any cholinergic neuron of the adult.
database_cross_reference: FBC:Autogenerated

adult dopaminergic neuron
type: Class
equivalent class: Class
  intersection of: dopaminergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: dopaminergic neuron
subclass of: adult aminergic neuron
definition: Any dopaminergic neuron of the adult.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058206
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058206
in subset: cur

Axiom
annotated source: adult dopaminergic neuron
annotated property: definition
annotated target: Any dopaminergic neuron of the adult.
database_cross_reference: FBC:Autogenerated

adult GABAergic neuron
type: Class
equivalent class: Class
  intersection of: GABAergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: GABAergic neuron
subclass of: adult neuron
definition: Any GABAergic neuron of the adult.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058207
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058207
in subset: cur

Axiom
annotated source: adult GABAergic neuron
annotated property: definition
annotated target: Any GABAergic neuron of the adult.
database_cross_reference: FBC:Autogenerated

adult glutamatergic neuron
type: Class
equivalent class: Class
  intersection of: glutamatergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult neuron
subclass of: glutamatergic neuron
definition: Any glutamatergic neuron of the adult.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058208
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058208
in subset: cur

Axiom
annotated source: adult glutamatergic neuron
annotated property: definition
annotated target: Any glutamatergic neuron of the adult.
database_cross_reference: FBC:Autogenerated

adult histaminergic neuron
type: Class
equivalent class: Class
  intersection of: histaminergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: histaminergic neuron
subclass of: adult aminergic neuron
definition: Any histaminergic neuron of the adult.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058210
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058210
in subset: cur

Axiom
annotated source: adult histaminergic neuron
annotated property: definition
annotated target: Any histaminergic neuron of the adult.
database_cross_reference: FBC:Autogenerated

larval aminergic neuron
type: Class
equivalent class: Class
  intersection of: aminergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuron
subclass of: aminergic neuron
definition: Any aminergic neuron of the larva.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058211
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058211
in subset: cur

Axiom
annotated source: larval aminergic neuron
annotated property: definition
annotated target: Any aminergic neuron of the larva.
database_cross_reference: FBC:Autogenerated

larval cholinergic neuron
type: Class
equivalent class: Class
  intersection of: cholinergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuron
subclass of: cholinergic neuron
definition: Any cholinergic neuron of the larva.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058215
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058215
in subset: cur

Axiom
annotated source: larval cholinergic neuron
annotated property: definition
annotated target: Any cholinergic neuron of the larva.
database_cross_reference: FBC:Autogenerated

larval dopaminergic neuron
type: Class
equivalent class: Class
  intersection of: dopaminergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: dopaminergic neuron
subclass of: larval aminergic neuron
definition: Any dopaminergic neuron of the larva.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058216
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058216
in subset: cur

Axiom
annotated source: larval dopaminergic neuron
annotated property: definition
annotated target: Any dopaminergic neuron of the larva.
database_cross_reference: FBC:Autogenerated

larval GABAergic neuron
type: Class
equivalent class: Class
  intersection of: GABAergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuron
subclass of: GABAergic neuron
definition: Any GABAergic neuron of the larva.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058217
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058217
in subset: cur

Axiom
annotated source: larval GABAergic neuron
annotated property: definition
annotated target: Any GABAergic neuron of the larva.
database_cross_reference: FBC:Autogenerated

larval glutamatergic neuron
type: Class
equivalent class: Class
  intersection of: glutamatergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuron
subclass of: glutamatergic neuron
definition: Any glutamatergic neuron of the larva.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058218
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058218
in subset: cur

Axiom
annotated source: larval glutamatergic neuron
annotated property: definition
annotated target: Any glutamatergic neuron of the larva.
database_cross_reference: FBC:Autogenerated

larval histaminergic neuron
type: Class
equivalent class: Class
  intersection of: histaminergic neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: histaminergic neuron
subclass of: larval aminergic neuron
definition: Any histaminergic neuron of the larva.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-03T18:57:00Z
database_cross_reference: VFB:FBbt_00058220
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058220
in subset: cur

Axiom
annotated source: larval histaminergic neuron
annotated property: definition
annotated target: Any histaminergic neuron of the larva.
database_cross_reference: FBC:Autogenerated

adult optic lobe cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: cell body rind of adult optic lobe
subclass of: adult brain cell body glial cell
subclass of: adult optic lobe glial cell
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult optic lobe
definition: Any glial cell (FBbt:00005144) that is part of some cell body rind of adult optic lobe (FBbt:00111152).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-25T13:41:46Z
database_cross_reference: VFB:FBbt_00058223
has exact synonym: adult optic lobe cortex glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058223
in subset: cur

Axiom
annotated source: adult optic lobe cell body glial cell
annotated property: definition
annotated target: Any glial cell (FBbt:00005144) that is part of some cell body rind of adult optic lobe (FBbt:00111152).
database_cross_reference: FBC:DPG

Axiom
annotated source: adult optic lobe cell body glial cell
annotated property: hasExactSynonym
annotated target: adult optic lobe cortex glial cell
database_cross_reference: FlyBase:FBrf0224194

adult optic lobe ensheathing glial cell
type: Class
equivalent class: Class
  intersection of: ensheathing glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult optic lobe
subclass of: adult optic lobe neuropil associated glial cell
subclass of: adult ensheathing glial cell
definition: Any ensheathing glial cell (FBbt:00047836) that is part of some adult optic lobe (FBbt:00003701).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-25T13:46:38Z
database_cross_reference: VFB:FBbt_00058224
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058224
in subset: cur

Axiom
annotated source: adult optic lobe ensheathing glial cell
annotated property: definition
annotated target: Any ensheathing glial cell (FBbt:00047836) that is part of some adult optic lobe (FBbt:00003701).
database_cross_reference: FBC:DPG

adult optic lobe neuropil associated glial cell
type: Class
equivalent class: Class
  intersection of: neuropil glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult optic lobe
subclass of: adult brain neuropil glial cell
subclass of: adult optic lobe glial cell
definition: Any neuropil glial cell (FBbt:00001303) that is part of some adult optic lobe (FBbt:00003701).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-06-25T14:07:29Z
database_cross_reference: VFB:FBbt_00058226
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058226
in subset: cur

Axiom
annotated source: adult optic lobe neuropil associated glial cell
annotated property: definition
annotated target: Any neuropil glial cell (FBbt:00001303) that is part of some adult optic lobe (FBbt:00003701).
database_cross_reference: FBC:DPG

lobula-lobula plate columnar neuron LLPC1
type: Class
subclass of: lobula-lobula plate columnar neuron LLPC
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: has characteristic
  some values from: PATO_0000634
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula plate layer 1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula plate layer 2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula plate layer 3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: posterior lateral protocerebrum
IAO_0000028: LLPC1
definition: Lobula-lobula plate columnar neuron that receives input from around 5-10 columns of lobula layer 4 and around 10 columns of lobula plate layer 1, with additional postsynapses in lobula plate layers 2-3 (Isaacson, 2019; Davis et al., 2020; Nern et al., 2025). It remains ipsilateral and sends output to the posterior lateral protocerebrum (Dorkenwald et al., 2024; Schlegel et al., 2024). It is highly sensitive to front-to-back motion on the ipsilateral eye (Isaacson, 2019). It is cholinergic (Davis et al., 2020). There are around 100-120 of these cells on each side (Nern et al., 2025).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-07-15T10:42:07Z
database_cross_reference: VFB:FBbt_00058227
has exact synonym: LLPC1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058227
in subset: cur

Axiom
annotated source: lobula-lobula plate columnar neuron LLPC1
annotated property: definition
annotated target: Lobula-lobula plate columnar neuron that receives input from around 5-10 columns of lobula layer 4 and around 10 columns of lobula plate layer 1, with additional postsynapses in lobula plate layers 2-3 (Isaacson, 2019; Davis et al., 2020; Nern et al., 2025). It remains ipsilateral and sends output to the posterior lateral protocerebrum (Dorkenwald et al., 2024; Schlegel et al., 2024). It is highly sensitive to front-to-back motion on the ipsilateral eye (Isaacson, 2019). It is cholinergic (Davis et al., 2020). There are around 100-120 of these cells on each side (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0260535
database_cross_reference: FlyBase:FBrf0260546
database_cross_reference: FlyBase:FBrf0262545
database_cross_reference: doi:10.17863/CAM.36002

Axiom
annotated source: lobula-lobula plate columnar neuron LLPC1
annotated property: hasExactSynonym
annotated target: LLPC1
has synonym type: VFB SYMBOL

transmedullary neuron Tm9a
type: Class
subclass of: transmedullary neuron Tm9
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm9a
subclass of: Restriction
  on property: expresses
  some values from: FBgn0031903
IAO_0000028: Tm9a
definition: Transmedullary neuron Tm9 that targets the dorsal half of the lobula. It is distinguished from other Tm9 neurons by its expression of Wnt10 (Kurmangaliyev et al., 2020).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2022-08-09T17:11:59Z
database_cross_reference: VFB:FBbt_00058233
has exact synonym: Tm9a
has exact synonym: transmedullary neuron Tm9d
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058233
in subset: cur

Axiom
annotated source: transmedullary neuron Tm9a
annotated property: IAO_0000028
annotated target: Tm9a
database_cross_reference: FlyBase:FBrf0247594

Axiom
annotated source: transmedullary neuron Tm9a
annotated property: definition
annotated target: Transmedullary neuron Tm9 that targets the dorsal half of the lobula. It is distinguished from other Tm9 neurons by its expression of Wnt10 (Kurmangaliyev et al., 2020).
database_cross_reference: FlyBase:FBrf0247594

Axiom
annotated source: transmedullary neuron Tm9a
annotated property: hasExactSynonym
annotated target: Tm9a
database_cross_reference: FlyBase:FBrf0247594
has synonym type: VFB SYMBOL

Axiom
annotated source: transmedullary neuron Tm9a
annotated property: hasExactSynonym
annotated target: transmedullary neuron Tm9d
database_cross_reference: FlyBase:FBrf0247762

transmedullary neuron Tm9b
type: Class
subclass of: transmedullary neuron Tm9
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm9b
subclass of: Restriction
  on property: expresses
  some values from: FBgn0010453
IAO_0000028: Tm9b
definition: Transmedullary neuron Tm9 that targets the ventral half of the lobula. It is distinguished from other Tm9 neurons by its expression of Wnt4 (Kurmangaliyev et al., 2020).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2022-08-09T17:15:04Z
database_cross_reference: VFB:FBbt_00058234
has exact synonym: Tm9b
has exact synonym: transmedullary neuron Tm9v
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058234
in subset: cur

Axiom
annotated source: transmedullary neuron Tm9b
annotated property: IAO_0000028
annotated target: Tm9b
database_cross_reference: FlyBase:FBrf0247594

Axiom
annotated source: transmedullary neuron Tm9b
annotated property: definition
annotated target: Transmedullary neuron Tm9 that targets the ventral half of the lobula. It is distinguished from other Tm9 neurons by its expression of Wnt4 (Kurmangaliyev et al., 2020).
database_cross_reference: FlyBase:FBrf0247594

Axiom
annotated source: transmedullary neuron Tm9b
annotated property: hasExactSynonym
annotated target: Tm9b
database_cross_reference: FlyBase:FBrf0247594
has synonym type: VFB SYMBOL

Axiom
annotated source: transmedullary neuron Tm9b
annotated property: hasExactSynonym
annotated target: transmedullary neuron Tm9v
database_cross_reference: FlyBase:FBrf0247762

adult sensory neuron
type: Class
equivalent class: Class
  intersection of: adult neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: sensory neuron
subclass of: adult neuron
definition: Any adult neuron (FBbt:00047095) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-09-27T12:13:59Z
database_cross_reference: VFB:FBbt_00058244
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058244

Axiom
annotated source: adult sensory neuron
annotated property: definition
annotated target: Any adult neuron (FBbt:00047095) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
database_cross_reference: FBC:Autogenerated

embryonic/larval sensory neuron
type: Class
equivalent class: Class
  intersection of: larval neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0050906
subclass of: larval neuron
subclass of: sensory neuron
definition: Any larval neuron (FBbt:00001446) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-09-27T12:17:06Z
database_cross_reference: VFB:FBbt_00058245
has exact synonym: larval SN
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058245
in subset: cur

Axiom
annotated source: embryonic/larval sensory neuron
annotated property: definition
annotated target: Any larval neuron (FBbt:00001446) that is capable of some detection of stimulus involved in sensory perception (GO:0050906).
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: embryonic/larval sensory neuron
annotated property: hasExactSynonym
annotated target: larval SN
database_cross_reference: FlyBase:FBrf0253566

adult PNS glial cell
type: Class
equivalent class: Class
  intersection of: PNS glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: PNS glial cell
subclass of: adult glial cell
subclass of: Restriction
  on property: part of
  some values from: adult peripheral nervous system
definition: Any PNS glial cell of the adult.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-09-27T16:42:03Z
database_cross_reference: VFB:FBbt_00058258
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058258
in subset: cur

Axiom
annotated source: adult PNS glial cell
annotated property: definition
annotated target: Any PNS glial cell of the adult.
database_cross_reference: FBC:Autogenerated

larval PNS glial cell
type: Class
equivalent class: Class
  intersection of: PNS glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval glial cell
subclass of: PNS glial cell
subclass of: Restriction
  on property: part of
  some values from: larval peripheral nervous system
definition: Any PNS glial cell of the larva.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-09-27T16:42:39Z
database_cross_reference: VFB:FBbt_00058259
has exact synonym: embryonic/larval PNS glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058259
in subset: cur

Axiom
annotated source: larval PNS glial cell
annotated property: definition
annotated target: Any PNS glial cell of the larva.
database_cross_reference: FBC:Autogenerated

adult lamina neuropil associated glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: lamina
subclass of: adult optic lobe glial cell
subclass of: Restriction
  on property: part of
  some values from: lamina
definition: Glial cell located in the lamina neuropil (Kremer et al., 2017).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2021-09-30T09:49:28Z
database_cross_reference: VFB:FBbt_00058264
has OBO namespace: fly_anatomy.ontology
id: FBbt:00058264
in subset: cur

Axiom
annotated source: adult lamina neuropil associated glial cell
annotated property: definition
annotated target: Glial cell located in the lamina neuropil (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0234767

adult central brain intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: adult central brain
subclass of: adult interneuron
subclass of: Restriction
  on property: synapses restricted to region
  some values from: adult central brain
definition: Neuron with its synapses restricted to the central brain.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-06-13T16:35:14Z
database_cross_reference: VFB:FBbt_00059245
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059245
in subset: cur

Axiom
annotated source: adult central brain intrinsic neuron
annotated property: definition
annotated target: Neuron with its synapses restricted to the central brain.
database_cross_reference: FlyBase:FBrf0260535
database_cross_reference: FlyBase:FBrf0260546

adult visual neuropil intrinsic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: adult primary visual center
subclass of: visual system neuron
subclass of: adult interneuron
subclass of: Restriction
  on property: synapses restricted to region
  some values from: adult primary visual center
definition: Neuron with its synapses restricted to the primary visual centers of the adult, i.e. the optic lobes or ocellar ganglia.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-06-16T09:39:18Z
database_cross_reference: VFB:FBbt_00059247
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059247
in subset: cur

Axiom
annotated source: adult visual neuropil intrinsic neuron
annotated property: definition
annotated target: Neuron with its synapses restricted to the primary visual centers of the adult, i.e. the optic lobes or ocellar ganglia.
database_cross_reference: FlyBase:FBrf0260535
database_cross_reference: FlyBase:FBrf0260546

adult cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: cell body rind of adult central nervous system
subclass of: cell body glial cell
subclass of: adult CNS glial cell
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult central nervous system
definition: Glial cell of the adult that is associated with the cell body rind of the brain or the ventral nerve cord.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-11-09T15:38:09Z
database_cross_reference: VFB:FBbt_00059270
has exact synonym: adult cortex glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059270
in subset: cur

Axiom
annotated source: adult cell body glial cell
annotated property: definition
annotated target: Glial cell of the adult that is associated with the cell body rind of the brain or the ventral nerve cord.
database_cross_reference: FlyBase:FBrf0250530

Axiom
annotated source: adult cell body glial cell
annotated property: hasExactSynonym
annotated target: adult cortex glial cell
database_cross_reference: FlyBase:FBrf0250530

CNS neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: central nervous system
subclass of: neuron
subclass of: Restriction
  on property: has soma location
  some values from: central nervous system
definition: Any neuron that has its soma in the central nervous system.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-11-09T16:06:03Z
database_cross_reference: VFB:FBbt_00059271
has exact synonym: central nervous system neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059271
in subset: cur

Axiom
annotated source: CNS neuron
annotated property: definition
annotated target: Any neuron that has its soma in the central nervous system.
database_cross_reference: https://orcid.org/0000-0002-6095-8718

PNS neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: has soma location
    some values from: peripheral nervous system
subclass of: neuron
subclass of: Restriction
  on property: has soma location
  some values from: peripheral nervous system
definition: Any neuron that has its soma in the peripheral nervous system.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-11-09T16:08:28Z
database_cross_reference: VFB:FBbt_00059272
has exact synonym: peripheral nervous system neuron
has OBO namespace: fly_anatomy.ontology
has related synonym: afferent neuron
id: FBbt:00059272
in subset: cur

Axiom
annotated source: PNS neuron
annotated property: definition
annotated target: Any neuron that has its soma in the peripheral nervous system.
database_cross_reference: https://orcid.org/0000-0002-6095-8718

Axiom
annotated source: PNS neuron
annotated property: hasRelatedSynonym
annotated target: afferent neuron
database_cross_reference: FlyBase:FBrf0260546

larval CNS neuron
type: Class
equivalent class: Class
  intersection of: CNS neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuron
subclass of: CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: larval central nervous system
definition: Any neuron that has its soma in the late embryonic or larval central nervous system.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-11-09T16:11:09Z
database_cross_reference: VFB:FBbt_00059273
has exact synonym: embryonic/larval central nervous system neuron
has exact synonym: larval central nervous system neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059273
in subset: cur

Axiom
annotated source: larval CNS neuron
annotated property: definition
annotated target: Any neuron that has its soma in the late embryonic or larval central nervous system.
database_cross_reference: https://orcid.org/0000-0002-6095-8718

adult CNS neuron
type: Class
equivalent class: Class
  intersection of: CNS neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult neuron
subclass of: CNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: adult central nervous system
definition: Any neuron that has its soma in the adult central nervous system.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-11-09T16:11:42Z
database_cross_reference: VFB:FBbt_00059274
has exact synonym: adult central nervous system neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059274
in subset: cur

Axiom
annotated source: adult CNS neuron
annotated property: definition
annotated target: Any neuron that has its soma in the adult central nervous system.
database_cross_reference: https://orcid.org/0000-0002-6095-8718

larval PNS neuron
type: Class
equivalent class: Class
  intersection of: PNS neuron
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: larval neuron
subclass of: PNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: larval peripheral nervous system
definition: Any neuron that has its soma in the late embryonic or larval peripheral nervous system.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-11-09T16:12:15Z
database_cross_reference: VFB:FBbt_00059275
has exact synonym: embryonic/larval peripheral nervous system neuron
has exact synonym: larval peripheral nervous system neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059275
in subset: cur

Axiom
annotated source: larval PNS neuron
annotated property: definition
annotated target: Any neuron that has its soma in the late embryonic or larval peripheral nervous system.
database_cross_reference: https://orcid.org/0000-0002-6095-8718

adult PNS neuron
type: Class
equivalent class: Class
  intersection of: PNS neuron
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: adult neuron
subclass of: PNS neuron
subclass of: Restriction
  on property: has soma location
  some values from: adult peripheral nervous system
definition: Any neuron that has its soma in the adult peripheral nervous system.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2023-11-09T16:12:44Z
database_cross_reference: VFB:FBbt_00059276
has exact synonym: adult peripheral nervous system neuron
has OBO namespace: fly_anatomy.ontology
has related synonym: adult afferent neuron
id: FBbt:00059276
in subset: cur

Axiom
annotated source: adult PNS neuron
annotated property: definition
annotated target: Any neuron that has its soma in the adult peripheral nervous system.
database_cross_reference: https://orcid.org/0000-0002-6095-8718

Axiom
annotated source: adult PNS neuron
annotated property: hasRelatedSynonym
annotated target: adult afferent neuron
database_cross_reference: FlyBase:FBrf0260546

immature T neuron
type: Class
equivalent class: Class
  intersection of: immature neuron
  intersection of: Restriction
    on property: develops into
    some values from: T neuron
subclass of: immature adult optic lobe neuron
subclass of: immature adult optic lobe intrinsic neuron
subclass of: Restriction
  on property: develops into
  some values from: T neuron
definition: Immature secondary neuron that is a precursor to an adult T neuron (Hormann et al., 2020).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2024-04-12T13:56:49Z
database_cross_reference: VFB:FBbt_00059279
has exact synonym: developing T neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059279

Axiom
annotated source: immature T neuron
annotated property: definition
annotated target: Immature secondary neuron that is a precursor to an adult T neuron (Hormann et al., 2020).
database_cross_reference: FlyBase:FBrf0245647

glial cell of eye-antennal disc
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: eye-antennal disc
subclass of: larval glial cell
subclass of: Restriction
  on property: overlaps
  some values from: eye-antennal disc
definition: Any glial cell that is found in an eye-antennal disc (Gonzalez-Blas et al., 2020).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2024-04-18T16:40:39Z
database_cross_reference: VFB:FBbt_00059299
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059299

Axiom
annotated source: glial cell of eye-antennal disc
annotated property: definition
annotated target: Any glial cell that is found in an eye-antennal disc (Gonzalez-Blas et al., 2020).
database_cross_reference: FlyBase:FBrf0245749

somatic cell of ectoderm anlage
type: Class
equivalent class: Class
  intersection of: somatic cell
  intersection of: Restriction
    on property: part of
    some values from: ectoderm anlage
subclass of: somatic cell
subclass of: Restriction
  on property: part of
  some values from: ectoderm anlage
definition: A(n) somatic cell that is part of a(n) ectoderm anlage.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2024-04-24T15:19:10Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059301

Axiom
annotated source: somatic cell of ectoderm anlage
annotated property: definition
annotated target: A(n) somatic cell that is part of a(n) ectoderm anlage.
database_cross_reference: FBC:Autogenerated

somatic cell of ectoderm
type: Class
equivalent class: Class
  intersection of: somatic cell
  intersection of: Restriction
    on property: part of
    some values from: ectoderm
subclass of: somatic cell
subclass of: Restriction
  on property: part of
  some values from: ectoderm
definition: A(n) somatic cell that is part of a(n) ectoderm.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2024-04-24T15:19:10Z
has exact synonym: ectodermal cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059305

Axiom
annotated source: somatic cell of ectoderm
annotated property: definition
annotated target: A(n) somatic cell that is part of a(n) ectoderm.
database_cross_reference: FBC:Autogenerated

somatic cell of stage 5 embryo
type: Class
equivalent class: Class
  intersection of: somatic cell
  intersection of: Restriction
    on property: part of
    some values from: stage 5 embryo
subclass of: somatic cell
subclass of: Restriction
  on property: part of
  some values from: stage 5 embryo
definition: A(n) somatic cell that is part of a(n) stage 5 embryo.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2024-04-24T15:19:10Z
has exact synonym: blastoderm cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059313

Axiom
annotated source: somatic cell of stage 5 embryo
annotated property: definition
annotated target: A(n) somatic cell that is part of a(n) stage 5 embryo.
database_cross_reference: FBC:Autogenerated

lamina wide-field neuron
type: Class
subclass of: optic lobe intrinsic columnar neuron
subclass of: adult cholinergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
subclass of: Restriction
  on property: expresses
  some values from: FBgn0038402
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lamina
definition: An intrinsic columnar neuron of the visual system whose cell body is located in the medulla cortex and that has a main projection making wide-field arborizations in the lamina. It expresses the transcription factor Fer2 (Ozel et al., 2021) and is cholinergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0002-6095-8718
date: 2024-06-11T16:41:19Z
database_cross_reference: VFB:FBbt_00059323
has exact synonym: Lawf1-2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059323
in subset: cur

Axiom
annotated source: lamina wide-field neuron
annotated property: definition
annotated target: An intrinsic columnar neuron of the visual system whose cell body is located in the medulla cortex and that has a main projection making wide-field arborizations in the lamina. It expresses the transcription factor Fer2 (Ozel et al., 2021) and is cholinergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina wide-field neuron
annotated property: hasExactSynonym
annotated target: Lawf1-2
database_cross_reference: FlyBase:FBrf0253187

somatic cell of trunk ectoderm
type: Class
equivalent class: Class
  intersection of: somatic cell
  intersection of: Restriction
    on property: part of
    some values from: trunk ectoderm
subclass of: somatic cell of ectoderm
subclass of: Restriction
  on property: part of
  some values from: trunk ectoderm
definition: A(n) somatic cell that is part of a(n) trunk ectoderm.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2025-01-16T16:51:10Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059340

Axiom
annotated source: somatic cell of trunk ectoderm
annotated property: definition
annotated target: A(n) somatic cell that is part of a(n) trunk ectoderm.
database_cross_reference: FBC:Autogenerated

somatic cell of anterior ectoderm
type: Class
equivalent class: Class
  intersection of: somatic cell
  intersection of: Restriction
    on property: part of
    some values from: anterior ectoderm
subclass of: somatic cell of ectoderm
subclass of: Restriction
  on property: part of
  some values from: anterior ectoderm
definition: A(n) somatic cell that is part of a(n) anterior ectoderm.
contributor: https://orcid.org/0000-0002-6095-8718
date: 2025-01-16T16:51:10Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00059342

Axiom
annotated source: somatic cell of anterior ectoderm
annotated property: definition
annotated target: A(n) somatic cell that is part of a(n) anterior ectoderm.
database_cross_reference: FBC:Autogenerated

cell body rind region
type: Class
subclass of: multi-cell-component structure
subclass of: Restriction
  on property: part of
  some values from: cell body rind of the central nervous system
definition: A subdivision of the cell body rind of the central nervous system. It includes the neuronal cell bodies.
contributor: Simon-Reeve-2162827703
date: 2010-09-08T02:26:08Z
database_cross_reference: VFB:FBbt_00100200
has exact synonym: cell body layer
has exact synonym: cortex region
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100200
comment: Ito et al. (2014) may further subdivide cortex/rind regions into multiple facets. Subdivisions should be denoted by the addition of a single letter body-axis direction, e.g. rLHa for anterior to the lateral horn; rSMPm for medial to the superior medial protocerebrum, etc.

Axiom
annotated source: cell body rind region
annotated property: definition
annotated target: A subdivision of the cell body rind of the central nervous system. It includes the neuronal cell bodies.
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: https://orcid.org/0000-0002-7073-9172

Axiom
annotated source: cell body rind region
annotated property: hasExactSynonym
annotated target: cell body layer
database_cross_reference: FlyBase:FBrf0224194

adult lateral brain cell body rind
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: adult brain cell body rind
subclass of: Restriction
  on property: continuous with
  some values from: adult lateral horn
subclass of: Restriction
  on property: continuous with
  some values from: superior lateral protocerebrum
subclass of: Restriction
  on property: continuous with
  some values from: ventrolateral protocerebrum
subclass of: Restriction
  on property: continuous with
  some values from: anterior optic tubercle
subclass of: Restriction
  on property: continuous with
  some values from: posterior lateral protocerebrum
subclass of: Restriction
  on property: continuous with
  some values from: wedge
subclass of: Restriction
  on property: continuous with
  some values from: inferior posterior slope
subclass of: Restriction
  on property: continuous with
  some values from: saddle
definition: Region of the adult brain cell body rind found in the area between the central brain and the optic lobe (Ito et al., 2014). It includes the regions lateral to the anterior optic tubercle, superior lateral protocerebrum (pars lateralis), lateral horn, ventrolateral protocerebrum, wedge, saddle, inferior posterior slope and posterior lateral protocerebrum (Ito et al., 2014).
contributor: Simon-Reeve-2162827703
date: 2010-09-08T02:32:32Z
database_cross_reference: VFB:FBbt_00100201
has exact synonym: LCBR
has exact synonym: lateral cell body region
has exact synonym: lateral cell body rind
has OBO namespace: fly_anatomy.ontology
has related synonym: cell body rind of lateral neuropils
id: FBbt:00100201

Axiom
annotated source: adult lateral brain cell body rind
annotated property: definition
annotated target: Region of the adult brain cell body rind found in the area between the central brain and the optic lobe (Ito et al., 2014). It includes the regions lateral to the anterior optic tubercle, superior lateral protocerebrum (pars lateralis), lateral horn, ventrolateral protocerebrum, wedge, saddle, inferior posterior slope and posterior lateral protocerebrum (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult lateral brain cell body rind
annotated property: hasExactSynonym
annotated target: LCBR
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: adult lateral brain cell body rind
annotated property: hasExactSynonym
annotated target: lateral cell body region
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult lateral brain cell body rind
annotated property: hasExactSynonym
annotated target: lateral cell body rind
database_cross_reference: FlyBase:FBrf0224194

cell body rind of adult medulla
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult optic lobe
subclass of: Restriction
  on property: continuous with
  some values from: medulla
definition: Region of the adult brain cell body rind that overlies the medulla.
contributor: Simon-Reeve-2162827703
date: 2010-09-08T02:45:39Z
has alternative id: FBbt:00001937
database_cross_reference: VFB:FBbt_00100205
has exact synonym: cortex of medulla
has exact synonym: medulla cortex
has exact synonym: rME
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100205

Axiom
annotated source: cell body rind of adult medulla
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the medulla.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult medulla
annotated property: hasExactSynonym
annotated target: rME
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

cell body rind of adult lamina
type: Class
subclass of: anterior ectoderm derivative
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult optic lobe
subclass of: Restriction
  on property: continuous with
  some values from: lamina
subclass of: Restriction
  on property: develops from
  some values from: lamina anlage
definition: Region of the adult brain cell body rind that overlies the lamina.
contributor: Simon-Reeve-2162827703
date: 2010-09-08T02:46:53Z
has alternative id: FBbt:00001941
database_cross_reference: VFB:FBbt_00100206
has exact synonym: cortex of lamina
has exact synonym: rLA
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100206

Axiom
annotated source: cell body rind of adult lamina
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the lamina.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult lamina
annotated property: hasExactSynonym
annotated target: rLA
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

cell body rind of adult lobula
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult optic lobe
subclass of: Restriction
  on property: continuous with
  some values from: lobula
definition: Region of the adult brain cell body rind that overlies the lobula.
contributor: Simon-Reeve-2162827703
date: 2010-09-08T02:48:09Z
database_cross_reference: VFB:FBbt_00100207
has exact synonym: cortex of lobula
has exact synonym: rLO
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100207

Axiom
annotated source: cell body rind of adult lobula
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the lobula.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult lobula
annotated property: hasExactSynonym
annotated target: rLO
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

glutamatergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: capable of
    some values from: GO_0061535
subclass of: CL_0000679
subclass of: neuron
definition: Any neuron (FBbt:00005106) that is capable of some glutamate secretion, neurotransmission (GO:0061535).
contributor: Simon-Reeve-2162827703
date: 2010-10-13T02:35:30Z
database_cross_reference: CL:0000679
database_cross_reference: VFB:FBbt_00100291
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100291
comment: Some glutamatergic neurons express ChAT transcripts (and reporters) at low levels, but do not produce functional enzyme (Lacin et al., 2019 - FBrf0242251).

Axiom
annotated source: glutamatergic neuron
annotated property: definition
annotated target: Any neuron (FBbt:00005106) that is capable of some glutamate secretion, neurotransmission (GO:0061535).
database_cross_reference: FBC:Autogenerated

multicellular structure
type: Class
subclass of: anatomical structure
definition: Anatomical structure that has multiple cells as parts.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-11-02T02:25:04Z
database_cross_reference: UBERON:0010000
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100313

Axiom
annotated source: multicellular structure
annotated property: definition
annotated target: Anatomical structure that has multiple cells as parts.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

gut section
type: Class
subclass of: organ system subdivision
subclass of: Restriction
  on property: part of
  some values from: gut
definition: A subdivision of the gut along its long axis.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-11-02T05:21:35Z
database_cross_reference: UBERON:0004921
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100315

Axiom
annotated source: gut section
annotated property: definition
annotated target: A subdivision of the gut along its long axis.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

somatic cell
type: Class
subclass of: cell
definition: Any cell that is not a germ cell (Okada, 1998). During development, somatic cells differentiate into various types, but they do not persist beyond the lifespan of a single organism (Okada, 1998).
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-11-04T08:35:02Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100318

Axiom
annotated source: somatic cell
annotated property: definition
annotated target: Any cell that is not a germ cell (Okada, 1998). During development, somatic cells differentiate into various types, but they do not persist beyond the lifespan of a single organism (Okada, 1998).
database_cross_reference: FlyBase:FBrf0101973

adult alimentary canal
type: Class
subclass of: alimentary canal
subclass of: Restriction
  on property: part of
  some values from: adult digestive system
definition: The entire adult anatomical structure through which food and its digestion products are ingested, digested and excreted. At its anterior and posterior ends this includes structures that are not foregut or hindgut.
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100322
in subset: cur

Axiom
annotated source: adult alimentary canal
annotated property: definition
annotated target: The entire adult anatomical structure through which food and its digestion products are ingested, digested and excreted. At its anterior and posterior ends this includes structures that are not foregut or hindgut.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

embryonic/larval alimentary canal
type: Class
subclass of: alimentary canal
subclass of: Restriction
  on property: part of
  some values from: larval digestive system
definition: The entire embryonic/larval anatomical structure through which food and its digestion products are ingested, digested and excreted. At its anterior and posterior ends this includes structures that are not foregut or hindgut.
contributor: https://orcid.org/0000-0002-7073-9172
date: 2010-11-04T02:13:05Z
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100323

Axiom
annotated source: embryonic/larval alimentary canal
annotated property: definition
annotated target: The entire embryonic/larval anatomical structure through which food and its digestion products are ingested, digested and excreted. At its anterior and posterior ends this includes structures that are not foregut or hindgut.
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult anterior optic tract
type: Class
subclass of: fascicle
subclass of: Restriction
  on property: part of
  some values from: adult cerebral ganglion
subclass of: Restriction
  on property: innervates
  some values from: lobula
subclass of: Restriction
  on property: innervates
  some values from: anterior optic tubercle
subclass of: Restriction
  on property: innervates
  some values from: posterior ventrolateral protocerebrum
definition: Tract that emerges from the medial part of the lobula (Ito et al., 2014). One branch ends in the anterior optic tubercle (AOTU) whilst the other makes a medial turn to terminate in the superior medial posterior ventrolateral protocerebrum (PVLP) of the adult brain (Ito et al., 2014). It demarcates the boundaries of the PVLP (lateral region), anterior VLP (superior and lateral region), AOTU (inferior-lateral region) and lateral horn (inferior region) (Ito et al., 2014).
contributor: Simon-Reeve-2162827703
date: 2010-11-30T11:51:04Z
database_cross_reference: VFB:FBbt_00100337
has exact synonym: AOT
has narrow synonym: MT tract
has narrow synonym: medulla-tubercle tract
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100337
comment: Fischbach and Lyly-Hunerberg, (1983), subdivide the anterior optic tract (AOT) into four sub-bundles: S1-S4. S1 consists of 100-110 think axons surrounded by ~60 large diameter neurons that form the S2 bundle. These bundles together occupy the proximal part of the AOT close to the neuropil of the lateral protocerebrum. S3 forms the lateral ventral part of the AOT and is formed by ~430 axons of small diameter that project into the anterior optic foci. S4 is composed of approximately 660 relatively small fibers.

Axiom
annotated source: adult anterior optic tract
annotated property: definition
annotated target: Tract that emerges from the medial part of the lobula (Ito et al., 2014). One branch ends in the anterior optic tubercle (AOTU) whilst the other makes a medial turn to terminate in the superior medial posterior ventrolateral protocerebrum (PVLP) of the adult brain (Ito et al., 2014). It demarcates the boundaries of the PVLP (lateral region), anterior VLP (superior and lateral region), AOTU (inferior-lateral region) and lateral horn (inferior region) (Ito et al., 2014).
database_cross_reference: FlyBase:FBrf0039022
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult anterior optic tract
annotated property: hasExactSynonym
annotated target: AOT
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: adult anterior optic tract
annotated property: hasNarrowSynonym
annotated target: MT tract
database_cross_reference: FlyBase:FBrf0248513

plexiform lamina
type: Class
subclass of: synaptic neuropil subdomain
subclass of: Restriction
  on property: part of
  some values from: lamina
definition: The main part of the lamina that does not contain the terminals of photoreceptors from dorsal rim ommatidia.
database_cross_reference: VFB:FBbt_00100366
has exact synonym: PLLA
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100366

Axiom
annotated source: plexiform lamina
annotated property: definition
annotated target: The main part of the lamina that does not contain the terminals of photoreceptors from dorsal rim ommatidia.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: plexiform lamina
annotated property: hasExactSynonym
annotated target: PLLA
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

lobula columnar neuron LC10
type: Class
subclass of: lobula columnar neuron
subclass of: Restriction
  on property: has soma location
  some values from: adult lateral brain cell body rind
subclass of: Restriction
  on property: fasciculates with
  some values from: adult anterior optic tract
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: anterior optic tubercle
IAO_0000028: LC10
definition: Lobula columnar neuron whose cell body lies in the dorsal region of the lateral cell body region. Its axon crosses ipsilaterally along the anterior optic tract, projecting to the anterior optic tubercle (AOTU). There are 2 main subtypes, which differ in how they project in the AOTU. For each subtype the relative order of the terminals along the dorsal/ventral axis of the AOTU matches the order along the anterior/posterior axis in the lobula.
contributor: Simon-Reeve-2162827703
date: 2011-04-12T02:08:27Z
has broad synonym: S3
database_cross_reference: FlyBrain_NDB:10010
database_cross_reference: VFB:FBbt_00100482
has exact synonym: LC10
has exact synonym: Lcn10
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100482

Axiom
annotated source: lobula columnar neuron LC10
annotated property: IAO_0000028
annotated target: LC10
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula columnar neuron LC10
annotated property: definition
annotated target: Lobula columnar neuron whose cell body lies in the dorsal region of the lateral cell body region. Its axon crosses ipsilaterally along the anterior optic tract, projecting to the anterior optic tubercle (AOTU). There are 2 main subtypes, which differ in how they project in the AOTU. For each subtype the relative order of the terminals along the dorsal/ventral axis of the AOTU matches the order along the anterior/posterior axis in the lobula.
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0233032
database_cross_reference: FlyBase:FBrf0234700

Axiom
annotated source: lobula columnar neuron LC10
annotated property: hasBroadSynonym
annotated target: S3
database_cross_reference: FlyBase:FBrf0039022

Axiom
annotated source: lobula columnar neuron LC10
annotated property: hasExactSynonym
annotated target: LC10
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

lobula tangential neuron LT11
type: Class
subclass of: lobula tangential neuron
subclass of: Restriction
  on property: has soma location
  some values from: adult lateral brain cell body rind
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: ventrolateral protocerebrum
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: transmedullary neuron Tm20
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: transmedullary neuron Tm5a
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: transmedullary neuron Tm5b
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: transmedullary neuron Tm5c
IAO_0000028: LT11
definition: A lobula tangential neuron whose cell body is located in the anterior dorsal area of the lateral cell body region. It forms varicosities in lobula layers 3, 4 and 5, and in the ventrolateral protocerebrum. It receives substantial synaptic input from Tm5a/b/c and Tm20 neurons, with a small number of synapses from each of a large number of Tm cells (Lin et al., 2016). There is only one neuron of this type per hemisphere.
contributor: Simon-Reeve-2162827703
date: 2011-04-14T01:20:48Z
database_cross_reference: FlyBrain_NDB:10016
database_cross_reference: VFB:FBbt_00100487
has exact synonym: LT11
has exact synonym: lobular tangential neuron LT11
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100487
comment: Connectivity data was assessed by GRASP and double-labeling EM (Lin et al., 2016).

Axiom
annotated source: lobula tangential neuron LT11
annotated property: IAO_0000028
annotated target: LT11
database_cross_reference: FlyBase:FBrf0193607

Axiom
annotated source: lobula tangential neuron LT11
annotated property: definition
annotated target: A lobula tangential neuron whose cell body is located in the anterior dorsal area of the lateral cell body region. It forms varicosities in lobula layers 3, 4 and 5, and in the ventrolateral protocerebrum. It receives substantial synaptic input from Tm5a/b/c and Tm20 neurons, with a small number of synapses from each of a large number of Tm cells (Lin et al., 2016). There is only one neuron of this type per hemisphere.
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0230403

Axiom
annotated source: lobula tangential neuron LT11
annotated property: hasExactSynonym
annotated target: LT11
database_cross_reference: FlyBase:FBrf0193607
has synonym type: VFB SYMBOL

adult glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: glial cell
subclass of: Restriction
  on property: part of
  some values from: adult nervous system
definition: Glial cell that is part of the adult. Subtypes generally tend to tile, minimizing contact with their glial neighbors and maximizing contact with their neuronal compartment (Kremer et al., 2017). They also do not seem to recognize particular neurons or neuropils; sometimes one glial cell has partial coverage of multiple units and multiple glial cells may tile across the same unit (Kremer et al., 2017).
contributor: Simon-Reeve-2162827703
date: 2011-04-19T01:31:16Z
database_cross_reference: VFB:FBbt_00100497
has OBO namespace: fly_anatomy.ontology
has related synonym: glia
id: FBbt:00100497

Axiom
annotated source: adult glial cell
annotated property: definition
annotated target: Glial cell that is part of the adult. Subtypes generally tend to tile, minimizing contact with their glial neighbors and maximizing contact with their neuronal compartment (Kremer et al., 2017). They also do not seem to recognize particular neurons or neuropils; sometimes one glial cell has partial coverage of multiple units and multiple glial cells may tile across the same unit (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0206543
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0234767

adult CNS glial cell
type: Class
equivalent class: Class
  intersection of: CNS glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: CNS glial cell
subclass of: adult glial cell
subclass of: Restriction
  on property: part of
  some values from: adult central nervous system
definition: Glial cell that is part of the adult central nervous system.
contributor: Simon-Reeve-2162827703
date: 2011-04-26T02:22:14Z
database_cross_reference: VFB:FBbt_00100499
has exact synonym: adult central nervous system glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100499

Axiom
annotated source: adult CNS glial cell
annotated property: definition
annotated target: Glial cell that is part of the adult central nervous system.
database_cross_reference: FlyBase:FBrf0206543

adult brain cell body glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult brain cell body rind
subclass of: adult cell body glial cell
subclass of: Restriction
  on property: part of
  some values from: adult brain cell body glial mesh
definition: Glial cell of the adult that is associated with the cell body rind of the brain. They have multiple lamelliform processes that intercalate in between neurons and wrap neuronal cell bodies (Hartenstein, 2011). They also wrap neuronal processes as they travel across the cell body rind (Kremer et al., 2017).
contributor: Simon-Reeve-2162827703
date: 2011-04-26T02:25:30Z
database_cross_reference: VFB:FBbt_00100501
has exact synonym: adult brain CG
has exact synonym: adult brain cortex associated glial cell
has exact synonym: adult brain cortex glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100501

Axiom
annotated source: adult brain cell body glial cell
annotated property: definition
annotated target: Glial cell of the adult that is associated with the cell body rind of the brain. They have multiple lamelliform processes that intercalate in between neurons and wrap neuronal cell bodies (Hartenstein, 2011). They also wrap neuronal processes as they travel across the cell body rind (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0206543
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0224194
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult brain cell body glial cell
annotated property: hasExactSynonym
annotated target: adult brain CG
database_cross_reference: FlyBase:FBrf0234767

adult neuropil glial cell
type: Class
equivalent class: Class
  intersection of: neuropil glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: neuropil glial cell
subclass of: adult CNS glial cell
subclass of: Restriction
  on property: part of
  some values from: adult neuropil glial sheath
definition: Glial cell of the adult that is associated with a neuropil of the brain. There are approximately 200 neuropil associated glial cells per hemisphere of the adult brain (Hartenstein, 2011).
contributor: Simon-Reeve-2162827703
date: 2011-04-26T02:36:23Z
database_cross_reference: VFB:FBbt_00100502
has exact synonym: adult neuropil associated glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100502

Axiom
annotated source: adult neuropil glial cell
annotated property: definition
annotated target: Glial cell of the adult that is associated with a neuropil of the brain. There are approximately 200 neuropil associated glial cells per hemisphere of the adult brain (Hartenstein, 2011).
database_cross_reference: FlyBase:FBrf0206543
database_cross_reference: FlyBase:FBrf0214261

adult brain cell body glial mesh
type: Class
subclass of: BFO_0000040
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: adult brain cell body rind
subclass of: Restriction
  on property: composed primarily of
  some values from: adult brain cell body glial cell
definition: Mesh-like structure composed of glial cells found in the cell body rind (cortex) of the adult brain (Awasaki et al., 2008). It is composed of cell body glial cells that locally elaborate and enwrap neuronal cell bodies (Awasaki et al., 2008).
contributor: Simon-Reeve-2162827703
date: 2011-04-26T03:22:32Z
database_cross_reference: VFB:FBbt_00100503
has exact synonym: adult brain cortex glial mesh
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100503

Axiom
annotated source: adult brain cell body glial mesh
annotated property: definition
annotated target: Mesh-like structure composed of glial cells found in the cell body rind (cortex) of the adult brain (Awasaki et al., 2008). It is composed of cell body glial cells that locally elaborate and enwrap neuronal cell bodies (Awasaki et al., 2008).
database_cross_reference: FlyBase:FBrf0206543

adult ensheathing glial cell
type: Class
equivalent class: Class
  intersection of: ensheathing glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: ensheathing glial cell
subclass of: adult neuropil glial cell
definition: Glial cell of the adult central nervous system that elaborates along the outer surface of its associated neuropil. Glia of this class may also surround neuropil bundles such as commissures or tracts. There are over 1000 of these in the adult central nervous system, some of which are descendants of larval ensheathing glia (Pogodalla et al., 2021).
contributor: Simon-Reeve-2162827703
date: 2011-04-26T04:17:41Z
database_cross_reference: VFB:FBbt_00100504
has exact synonym: adult EG
has exact synonym: adult ensheathing neuropil associated glial cell
has exact synonym: adult fibrous lamellar neuropil associated glial cell
has exact synonym: adult neuropil ensheathing glial cell
has narrow synonym: sEG
has narrow synonym: secondary ensheathing glia
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100504

Axiom
annotated source: adult ensheathing glial cell
annotated property: definition
annotated target: Glial cell of the adult central nervous system that elaborates along the outer surface of its associated neuropil. Glia of this class may also surround neuropil bundles such as commissures or tracts. There are over 1000 of these in the adult central nervous system, some of which are descendants of larval ensheathing glia (Pogodalla et al., 2021).
database_cross_reference: FlyBase:FBrf0206543
database_cross_reference: FlyBase:FBrf0234767
database_cross_reference: FlyBase:FBrf0251788

Axiom
annotated source: adult ensheathing glial cell
annotated property: hasExactSynonym
annotated target: adult EG
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult ensheathing glial cell
annotated property: hasNarrowSynonym
annotated target: sEG
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: adult ensheathing glial cell
annotated property: hasNarrowSynonym
annotated target: secondary ensheathing glia
database_cross_reference: FlyBase:FBrf0229106

astrocyte-like glial cell
type: Class
subclass of: neuropil glial cell
subclass of: Restriction
  on property: expresses
  some values from: FBgn0004595
definition: Neuropil associated glial cell of the central nervous system that has a dendritic morphology and elaborates inside the associated synaptic neuropil (Awasaki et al., 2008). Their nuclei are found at synaptic neuropil surfaces and they extend branched filiform or lamelliform processes that pervade the neuropil (Hartenstein, 2011). It expresses prospero, which specifies astrocyte-like, rather than ensheathing, fate in lineages that produce neuropil glia (Peco et al., 2016; Kato et al., 2020).
contributor: Simon-Reeve-2162827703
date: 2011-04-26T04:23:17Z
database_cross_reference: VFB:FBbt_00100505
has exact synonym: ALG
has exact synonym: astrocyte
has exact synonym: astrocyte-like neuropil associated glial cell
has exact synonym: astrocytic glia
has exact synonym: dendritic neuropil associated glial cell
has exact synonym: reticular glial cell
has exact synonym: reticular neuropil associated glial cell
has exact synonym: reticular neuropil-associated glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100505

Axiom
annotated source: astrocyte-like glial cell
annotated property: definition
annotated target: Neuropil associated glial cell of the central nervous system that has a dendritic morphology and elaborates inside the associated synaptic neuropil (Awasaki et al., 2008). Their nuclei are found at synaptic neuropil surfaces and they extend branched filiform or lamelliform processes that pervade the neuropil (Hartenstein, 2011). It expresses prospero, which specifies astrocyte-like, rather than ensheathing, fate in lineages that produce neuropil glia (Peco et al., 2016; Kato et al., 2020).
database_cross_reference: FlyBase:FBrf0206543
database_cross_reference: FlyBase:FBrf0207750
database_cross_reference: FlyBase:FBrf0214261
database_cross_reference: FlyBase:FBrf0225669
database_cross_reference: FlyBase:FBrf0231858
database_cross_reference: FlyBase:FBrf0245107

Axiom
annotated source: astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: ALG
database_cross_reference: FlyBase:FBrf0229106

Axiom
annotated source: astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: astrocyte
database_cross_reference: FlyBase:FBrf0225669

Axiom
annotated source: astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: astrocyte-like neuropil associated glial cell
database_cross_reference: FlyBase:FBrf0206543

Axiom
annotated source: astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: astrocytic glia
database_cross_reference: FlyBase:FBrf0207750

Axiom
annotated source: astrocyte-like glial cell
annotated property: hasExactSynonym
annotated target: reticular neuropil-associated glial cell
database_cross_reference: FlyBase:FBrf0214261

developing satellite glial cell
type: Class
subclass of: CNS glial cell
subclass of: Restriction
  on property: develops into
  some values from: adult lamina satellite glial cell
definition: Glial cell that is in the process of becoming an adult satellite glial cell (Edwards et al., 2012). The two different populations of adult satellite glia arise from different larval precursors (Edwards et al., 2012).
contributor: Simon-Reeve-2162827703
date: 2011-05-10T11:19:05Z
database_cross_reference: VFB:FBbt_00100509
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100509

Axiom
annotated source: developing satellite glial cell
annotated property: definition
annotated target: Glial cell that is in the process of becoming an adult satellite glial cell (Edwards et al., 2012). The two different populations of adult satellite glia arise from different larval precursors (Edwards et al., 2012).
database_cross_reference: FlyBase:FBrf0218414

adult lamina epithelial glial cell
type: Class
equivalent class: Class
  intersection of: astrocyte-like glial cell
  intersection of: Restriction
    on property: part of
    some values from: lamina
subclass of: epithelial glial cell
subclass of: adult optic lobe astrocyte-like glial cell
subclass of: adult lamina neuropil associated glial cell
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: lamina intrinsic neuron Lai
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: outer photoreceptor cell
definition: Astrocyte-like (reticular) glial cell of the adult lamina (Edwards et al., 2012; Kremer et al., 2017). Each cell contributes to the wrapping of multiple columns and each column is wrapped by multiple glia (Edwards et al., 2012; Kremer et al., 2017). Epithelial glial cells elaborate numerous fine processes into the lamina plexus, especially from the surface juxtaposing the R1-R6 growth cones or axon termini (Poeck et al., 2001). In the lamina, they receive a small amount of synaptic input from each of photoreceptors R1-R6 and strong input from lamina intrinsic (amacrine) cells (Rivera-Alba et al., 2011). There are around 470 of these cells per lamina (Kremer et al., 2017).
contributor: Simon-Reeve-2162827703
date: 2011-05-10T03:42:15Z
database_cross_reference: VFB:FBbt_00100513
has exact synonym: L-ALG
has exact synonym: adult lamina astrocyte-like glial cell
has exact synonym: adult lamina reticular glial cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100513
comment: Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for a epithelial glial cell (presynaptic/postsynaptic) in a single lamina cartridge for each cell type was the following: R1 (-/15), R2 (-/13), R3 (-/7), R4 (-/9), R5 (-/10), R6 (-/11), Lai (-/87) (Rivera-Alba et al., 2011).

Axiom
annotated source: adult lamina epithelial glial cell
annotated property: definition
annotated target: Astrocyte-like (reticular) glial cell of the adult lamina (Edwards et al., 2012; Kremer et al., 2017). Each cell contributes to the wrapping of multiple columns and each column is wrapped by multiple glia (Edwards et al., 2012; Kremer et al., 2017). Epithelial glial cells elaborate numerous fine processes into the lamina plexus, especially from the surface juxtaposing the R1-R6 growth cones or axon termini (Poeck et al., 2001). In the lamina, they receive a small amount of synaptic input from each of photoreceptors R1-R6 and strong input from lamina intrinsic (amacrine) cells (Rivera-Alba et al., 2011). There are around 470 of these cells per lamina (Kremer et al., 2017).
database_cross_reference: FlyBase:FBrf0055906
database_cross_reference: FlyBase:FBrf0134808
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0209968
database_cross_reference: FlyBase:FBrf0210316
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina epithelial glial cell
annotated property: hasExactSynonym
annotated target: L-ALG
database_cross_reference: FlyBase:FBrf0234767

Axiom
annotated source: adult lamina epithelial glial cell
annotated property: hasExactSynonym
annotated target: adult lamina astrocyte-like glial cell
database_cross_reference: FlyBase:FBrf0234767

embryonic/larval epithelial glial cell
type: Class
equivalent class: Class
  intersection of: epithelial glial cell
  intersection of: Restriction
    on property: overlaps
    some values from: larva
subclass of: epithelial glial cell
subclass of: larval neuropil glial cell
subclass of: embryonic/larval lateral glial cell
definition: Epithelial glial cell of the embryo/larva.
contributor: Simon-Reeve-2162827703
date: 2011-05-10T03:44:02Z
database_cross_reference: VFB:FBbt_00100514
has exact synonym: lveg
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100514

Axiom
annotated source: embryonic/larval epithelial glial cell
annotated property: definition
annotated target: Epithelial glial cell of the embryo/larva.
database_cross_reference: FlyBase:FBrf0055906
database_cross_reference: FlyBase:FBrf0134808
database_cross_reference: FlyBase:FBrf0209968

Axiom
annotated source: embryonic/larval epithelial glial cell
annotated property: hasExactSynonym
annotated target: lveg
database_cross_reference: FlyBase:FBrf0243081

adult optic lobe glial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: part of
    some values from: adult optic lobe
subclass of: adult CNS glial cell
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
definition: Glial cell of the adult that is associated with the optic lobe.
contributor: Simon-Reeve-2162827703
date: 2011-05-12T02:14:56Z
database_cross_reference: VFB:FBbt_00100517
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100517

Axiom
annotated source: adult optic lobe glial cell
annotated property: definition
annotated target: Glial cell of the adult that is associated with the optic lobe.
database_cross_reference: FlyBase:FBrf0096428
database_cross_reference: FlyBase:FBrf0210316

type I neuroblast
type: Class
subclass of: neuroblast
subclass of: Restriction
  on property: expresses
  some values from: FBgn0000137
subclass of: Restriction
  on property: expresses
  some values from: FBgn0004595
subclass of: Restriction
  on property: expresses
  some values from: FBgn0010109
definition: Neuroblast that divides asymmetrically to regenerate itself and produce a smaller ganglion mother cell that generates two daughter neurons. Many of these neuroblasts switch to type 0 division at some point during their development, to produce daughters that develop into neurons with no further division (Baumgardt et al., 2014).
contributor: Simon-Reeve-2162827703
date: 2011-06-06T02:39:05Z
database_cross_reference: VFB:FBbt_00100532
has narrow synonym: type 0 neuroblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100532
comment: Bayraktar et al. (2010) show that type I neuroblasts can be distinguished from type II neuroblasts as being Deadpan-, Prospero- and Asense-positive.

Axiom
annotated source: type I neuroblast
annotated property: definition
annotated target: Neuroblast that divides asymmetrically to regenerate itself and produce a smaller ganglion mother cell that generates two daughter neurons. Many of these neuroblasts switch to type 0 division at some point during their development, to produce daughters that develop into neurons with no further division (Baumgardt et al., 2014).
database_cross_reference: FlyBase:FBrf0207387
database_cross_reference: FlyBase:FBrf0225698

Axiom
annotated source: type I neuroblast
annotated property: hasNarrowSynonym
annotated target: type 0 neuroblast
database_cross_reference: FlyBase:FBrf0225698

type II neuroblast
type: Class
subclass of: procephalic neuroblast
subclass of: Restriction
  on property: expresses
  some values from: FBgn0003118
subclass of: Restriction
  on property: expresses
  some values from: FBgn0010109
definition: Neuroblast that divides asymmetrically regenerate itself and produce a smaller intermediate neural progenitor (INP), which can produce multiple ganglion mother cells (Boone and Doe, 2008, Viktorin et al., 2011; Ren et al., 2016). Each type II neuroblast can produce multiple INPs, leading to the generation of multiple sublineages and typically more progeny than type I neuroblasts (Ren et al., 2016). It arises relatively late during embryonic development, delaminating from the dorsal cephalic neuroectoderm during stages 11-15 (Walsh and Doe, 2017). These cells and any existing INPs enter quiescence shortly before larval hatching (Walsh and Doe, 2017). There are eight type II neuroblasts per hemisphere, all belonging to the brain (Walsh and Doe, 2017).
contributor: Simon-Reeve-2162827703
date: 2011-06-06T02:54:10Z
database_cross_reference: VFB:FBbt_00100533
has exact synonym: TA neuroblast
has exact synonym: transiently amplifying neuroblast
has exact synonym: transit amplifying neuroblast
has OBO namespace: fly_anatomy.ontology
id: FBbt:00100533
comment: Bayraktar et al. (2010) show that type II neuroblasts can be distinguished from type I neuroblasts as being Deadpan-positive, but Prospero- and Asense-negative. Walsh and Doe (2017) also use pointed as a positive marker. Arise later than NBs of embryonic NB map in Urbach and Technau (2003) - FBrf0173125 (Walsh and Doe, 2017).

Axiom
annotated source: type II neuroblast
annotated property: definition
annotated target: Neuroblast that divides asymmetrically regenerate itself and produce a smaller intermediate neural progenitor (INP), which can produce multiple ganglion mother cells (Boone and Doe, 2008, Viktorin et al., 2011; Ren et al., 2016). Each type II neuroblast can produce multiple INPs, leading to the generation of multiple sublineages and typically more progeny than type I neuroblasts (Ren et al., 2016). It arises relatively late during embryonic development, delaminating from the dorsal cephalic neuroectoderm during stages 11-15 (Walsh and Doe, 2017). These cells and any existing INPs enter quiescence shortly before larval hatching (Walsh and Doe, 2017). There are eight type II neuroblasts per hemisphere, all belonging to the brain (Walsh and Doe, 2017).
database_cross_reference: FlyBase:FBrf0204899
database_cross_reference: FlyBase:FBrf0207387
database_cross_reference: FlyBase:FBrf0209927
database_cross_reference: FlyBase:FBrf0214289
database_cross_reference: FlyBase:FBrf0214495
database_cross_reference: FlyBase:FBrf0233706
database_cross_reference: FlyBase:FBrf0237530

late embryonic primordium of adult eye
type: Class
subclass of: embryonic primordium of adult eye
subclass of: Restriction
  on property: part of
  some values from: late embryo
subclass of: Restriction
  on property: develops from
  some values from: early embryonic primordium of adult eye
definition: Primordium of the late embryo that develops from the early primordium, and will give rise to the adult eye.
has exact synonym: adult eye primordium late
has OBO namespace: fly_anatomy.ontology
id: FBbt:00105515
in subset: cur

Axiom
annotated source: late embryonic primordium of adult eye
annotated property: definition
annotated target: Primordium of the late embryo that develops from the early primordium, and will give rise to the adult eye.
database_cross_reference: FBC:VH
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275
database_cross_reference: https://orcid.org/0000-0002-7073-9172

lamina wide-field 2 neuron
type: Class
subclass of: lamina wide-field neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M10
IAO_0000028: Lawf2
definition: A lamina wide-field neuron that has a main projection into the lamina making wide-field arborizations in the distal lamina, innervating 28 cartridges. These neurons also arborize in the medulla (Hasegawa et al., 2011). In the M1 layer, the branches are large and overlapping, encompassing around 120 cartridges. In medulla layers M8 to M10 the branches are smaller, encompassing around 17 cartridges and show less overlap. Putative cholinergic presynaptic sites are observed in the lamina.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2011-12-13T11:05:21Z
database_cross_reference: VFB:FBbt_00110065
has exact synonym: Lawf2
has exact synonym: Lawfl2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110065
in subset: cur

Axiom
annotated source: lamina wide-field 2 neuron
annotated property: IAO_0000028
annotated target: Lawf2
database_cross_reference: FlyBase:FBrf0225131
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina wide-field 2 neuron
annotated property: definition
annotated target: A lamina wide-field neuron that has a main projection into the lamina making wide-field arborizations in the distal lamina, innervating 28 cartridges. These neurons also arborize in the medulla (Hasegawa et al., 2011). In the M1 layer, the branches are large and overlapping, encompassing around 120 cartridges. In medulla layers M8 to M10 the branches are smaller, encompassing around 17 cartridges and show less overlap. Putative cholinergic presynaptic sites are observed in the lamina.
database_cross_reference: FlyBase:FBrf0213020
database_cross_reference: FlyBase:FBrf0225131
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: lamina wide-field 2 neuron
annotated property: hasExactSynonym
annotated target: Lawf2
database_cross_reference: FlyBase:FBrf0225131
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

Axiom
annotated source: lamina wide-field 2 neuron
annotated property: hasExactSynonym
annotated target: Lawfl2
database_cross_reference: FlyBase:FBrf0213020

proximal medullary amacrine neuron Pm3
type: Class
subclass of: adult optic lobe neuron
subclass of: proximal medullary amacrine neuron
subclass of: adult GABAergic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M9
IAO_0000028: Pm3
definition: Proximal medullary amacrine neuron that branches at the proximal surface of the medulla, with both branches forming a broad terminal arbor in medulla layer M9. The processes of different cells intermingle significantly, and the arbor density is heterogeneous. It occupies a peripheral intracolumnar position. It is GABAergic (Davis et al., 2020). There are around 35-40 of these cells per hemisphere (Nern et al., 2025).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2011-12-13T11:05:21Z
database_cross_reference: VFB:FBbt_00110066
has exact synonym: CB3856
has exact synonym: Pm09
has exact synonym: Pm3
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110066
in subset: cur

Axiom
annotated source: proximal medullary amacrine neuron Pm3
annotated property: IAO_0000028
annotated target: Pm3
database_cross_reference: FlyBase:FBrf0213020
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: proximal medullary amacrine neuron Pm3
annotated property: definition
annotated target: Proximal medullary amacrine neuron that branches at the proximal surface of the medulla, with both branches forming a broad terminal arbor in medulla layer M9. The processes of different cells intermingle significantly, and the arbor density is heterogeneous. It occupies a peripheral intracolumnar position. It is GABAergic (Davis et al., 2020). There are around 35-40 of these cells per hemisphere (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0213020
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: proximal medullary amacrine neuron Pm3
annotated property: hasExactSynonym
annotated target: CB3856
database_cross_reference: FlyBase:FBrf0260535
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: proximal medullary amacrine neuron Pm3
annotated property: hasExactSynonym
annotated target: Pm09
database_cross_reference: FlyBase:FBrf0260545
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: proximal medullary amacrine neuron Pm3
annotated property: hasExactSynonym
annotated target: Pm3
database_cross_reference: FlyBase:FBrf0213020
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm5a
type: Class
subclass of: transmedullary neuron Tm5
subclass of: narrow field transmedullary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: yellow optic column
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 5B
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R7 of yellow ommatidium
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lobula tangential neuron LT11
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lobula intrinsic neuron Li4
IAO_0000028: Tm5a
definition: Transmedullary Tm5 neuron that is centered on a single yellow column in the medulla and arborizes in the M3, M6 and M8 layers, reaching some neighboring columns laterally (Kind et al., 2021). It selectively receives input from the R7 (and not R8) photoreceptor of its central column (Kind et al., 2021). Its axon terminates in lobula layer 5B after a characteristic reversal of direction (Kind et al., 2021). It provides input to the lobula intrinsic neuron Li4 via many synapses, and also to the lobula tangential neuron LT11 (Lin et al., 2016). It is a cholinergic neuron (Karuppudurai et al., 2014).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2011-12-14T03:31:46Z
database_cross_reference: VFB:FBbt_00110072
has exact synonym: Tm5a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110072
in subset: cur
comment: Connectivity in the medulla inferred from EM reconstructions (Gao et al., 2008; Kind et al., 2021). The neurotransmitter was assessed by immunohistochemistry (Karuppudurai et al., 2014). Connectivity in the lobula was assessed by GRASP and double-labeling EM (Lin et al., 2016).

Axiom
annotated source: transmedullary neuron Tm5a
annotated property: IAO_0000028
annotated target: Tm5a
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm5a
annotated property: definition
annotated target: Transmedullary Tm5 neuron that is centered on a single yellow column in the medulla and arborizes in the M3, M6 and M8 layers, reaching some neighboring columns laterally (Kind et al., 2021). It selectively receives input from the R7 (and not R8) photoreceptor of its central column (Kind et al., 2021). Its axon terminates in lobula layer 5B after a characteristic reversal of direction (Kind et al., 2021). It provides input to the lobula intrinsic neuron Li4 via many synapses, and also to the lobula tangential neuron LT11 (Lin et al., 2016). It is a cholinergic neuron (Karuppudurai et al., 2014).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0230403
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: transmedullary neuron Tm5a
annotated property: hasExactSynonym
annotated target: Tm5a
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm5b
type: Class
subclass of: transmedullary neuron Tm5
subclass of: wide field transmedullary neuron
subclass of: Notch ON hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm5b
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: pale optic column
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R7 of pale ommatidium
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lobula intrinsic neuron Li4
IAO_0000028: Tm5b
definition: Transmedullary Tm5 neuron that extends two or three vertical main dendritic branches in the medulla, spanning around five columns, from which branches spread laterally into layers M3, M6 and M8 (Kind et al., 2021). It receives most of its inner (R7/R8) photoreceptor input from the R7 photoreceptors of pale ommatidia (Kind et al., 2021). Its axon innervates lobula layer 5 (Kind et al., 2021). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It is a cholinergic neuron (Karuppudurai et al., 2014).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2011-12-14T03:31:46Z
database_cross_reference: VFB:FBbt_00110073
has exact synonym: Tm5b
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110073
in subset: cur
comment: The neurotransmitter was assessed by immunohistochemistry (Karuppudurai et al., 2014). Connectivity in the lobula was assessed by GRASP and double-labeling EM (Lin et al., 2016). Photoreceptor input determined from EM (Kind et al., 2021).

Axiom
annotated source: transmedullary neuron Tm5b
annotated property: IAO_0000028
annotated target: Tm5b
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm5b
annotated property: definition
annotated target: Transmedullary Tm5 neuron that extends two or three vertical main dendritic branches in the medulla, spanning around five columns, from which branches spread laterally into layers M3, M6 and M8 (Kind et al., 2021). It receives most of its inner (R7/R8) photoreceptor input from the R7 photoreceptors of pale ommatidia (Kind et al., 2021). Its axon innervates lobula layer 5 (Kind et al., 2021). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It is a cholinergic neuron (Karuppudurai et al., 2014).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0230403
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: transmedullary neuron Tm5b
annotated property: hasExactSynonym
annotated target: Tm5b
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

transmedullary neuron Tm5c
type: Class
subclass of: transmedullary neuron Tm5
subclass of: wide field transmedullary neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature transmedullary neuron Tm5c
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: yellow optic column
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: photoreceptor cell R8
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: distal medullary amacrine neuron Dm8a
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lobula intrinsic neuron Li4
IAO_0000028: Tm5c
definition: Transmedullary Tm5 neuron that spans around eight medulla columns with lateral branches expanding out into the M1, M3 and M6 layers from a single vertical dendrite (Kind et al., 2021). It preferentially receives input from R8 (rather than R7) photoreceptor cells, and in most, but not all, cases these cells are selective for yellow (rather than pale) ommatidia (Kind et al., 2021). Its R8 input is mainly in layer M3 and it also receives input from the distal medullary amacrine neuron Dm8 in layer M6 (Karuppudurai et al., 2014). Its axon terminates near the boundary between lobula layers 5 and 6, with some cells having a branch in layer 4 (Kind et al., 2021). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It is a glutamatergic neuron (Gao et al., 2008; Karuppudurai et al., 2014).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2011-12-14T03:31:46Z
database_cross_reference: VFB:FBbt_00110074
has exact synonym: Tm5c
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110074
in subset: cur
comment: The neurotransmitter was assessed in cells labelled with a glutamate GAL4 driver P{GawB}vGlut[OK371] (FBti0076967) (Gao et al., 2008), RT-PCR and by immunohistochemistry (Karuppudurai et al., 2014). Connectivity inferred from GRASP experiments (Karuppudurai et al., 2014; Lin et al., 2016), from EM reconstructions (Kind et al., 2021) or from double-labeling EM (Lin et al., 2016).

Axiom
annotated source: transmedullary neuron Tm5c
annotated property: IAO_0000028
annotated target: Tm5c
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: transmedullary neuron Tm5c
annotated property: definition
annotated target: Transmedullary Tm5 neuron that spans around eight medulla columns with lateral branches expanding out into the M1, M3 and M6 layers from a single vertical dendrite (Kind et al., 2021). It preferentially receives input from R8 (rather than R7) photoreceptor cells, and in most, but not all, cases these cells are selective for yellow (rather than pale) ommatidia (Kind et al., 2021). Its R8 input is mainly in layer M3 and it also receives input from the distal medullary amacrine neuron Dm8 in layer M6 (Karuppudurai et al., 2014). Its axon terminates near the boundary between lobula layers 5 and 6, with some cells having a branch in layer 4 (Kind et al., 2021). It provides input to the lobula intrinsic neuron Li4 via many synapses (Lin et al., 2016). It is a glutamatergic neuron (Gao et al., 2008; Karuppudurai et al., 2014).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0230403
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: transmedullary neuron Tm5c
annotated property: hasExactSynonym
annotated target: Tm5c
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

distal medullary amacrine neuron Dm10
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult GABAergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm10
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla sublayer M3B
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla sublayer M3B
IAO_0000028: Dm10
definition: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. It has a distinct tri-stratified layer pattern, branching extensively in medulla layers M1, M3B and M5. Its arbor resembles an ellipse, with the long axis aligned with the dorsal-ventral axis, and covering less than 10 columns. The processes in M1 and M3B to M5 are located in an intracolumnar position. There are around 300 Dm10 neurons per hemisphere. They are GABAergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2012-05-22T02:28:19Z
database_cross_reference: VFB:FBbt_00110135
has exact synonym: Dm1-5
has exact synonym: Dm10
has exact synonym: distal medullary amacrine neuron Dm1-5
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110135
in subset: cur
comment: Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt} - FBtp0015803). The identification of dendrites and axons was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP} - FBtp0021447) or a UAS-tau (P{SUAS-tau-lacZ.O} - FBtp0010033) reporter, respectively (Morante and Desplan, 2008).

Axiom
annotated source: distal medullary amacrine neuron Dm10
annotated property: IAO_0000028
annotated target: Dm10
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm10
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. It has a distinct tri-stratified layer pattern, branching extensively in medulla layers M1, M3B and M5. Its arbor resembles an ellipse, with the long axis aligned with the dorsal-ventral axis, and covering less than 10 columns. The processes in M1 and M3B to M5 are located in an intracolumnar position. There are around 300 Dm10 neurons per hemisphere. They are GABAergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0204652
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0244935

Axiom
annotated source: distal medullary amacrine neuron Dm10
annotated property: hasExactSynonym
annotated target: Dm1-5
database_cross_reference: FlyBase:FBrf0204652

Axiom
annotated source: distal medullary amacrine neuron Dm10
annotated property: hasExactSynonym
annotated target: Dm10
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

Axiom
annotated source: distal medullary amacrine neuron Dm10
annotated property: hasExactSynonym
annotated target: distal medullary amacrine neuron Dm1-5
database_cross_reference: FlyBase:FBrf0204652

optic lobe narrow field columnar neuron
type: Class
subclass of: adult optic lobe columnar neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: optic column
definition: Columnar interneuron of the optic lobe whose collaterals are restricted to a single optic column.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2012-07-23T02:45:37Z
database_cross_reference: VFB:FBbt_00110136
has exact synonym: optic lobe uni-columnar neuron
has exact synonym: optic lobe unicolumnar neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110136
in subset: cur
comment: This definition follows Fischbach and Dittrich (1989) in classifying based on the extension of the collaterals. A narrow field columnar neuron is classified as columnar by Morante and Desplan (2008).

Axiom
annotated source: optic lobe narrow field columnar neuron
annotated property: definition
annotated target: Columnar interneuron of the optic lobe whose collaterals are restricted to a single optic column.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652

Axiom
annotated source: optic lobe narrow field columnar neuron
annotated property: hasExactSynonym
annotated target: optic lobe uni-columnar neuron
database_cross_reference: FlyBase:FBrf0260546

optic lobe wide-field columnar neuron
type: Class
subclass of: adult optic lobe columnar neuron
definition: Columnar interneuron of the optic lobe whose collaterals extend over more than one optic column.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2012-07-23T02:45:37Z
database_cross_reference: VFB:FBbt_00110137
has exact synonym: optic lobe multi-columnar neuron
has exact synonym: optic lobe multicolumnar neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110137
in subset: cur
comment: This definition follows Fischbach and Dittrich (1989) in classifying based on the extension of the collaterals. A wide-field columnar neuron is classified as non-columnar by Morante and Desplan (2008).

Axiom
annotated source: optic lobe wide-field columnar neuron
annotated property: definition
annotated target: Columnar interneuron of the optic lobe whose collaterals extend over more than one optic column.
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0204652

cell body rind of adult deutocerebrum
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: adult brain cell body rind
subclass of: Restriction
  on property: part of
  some values from: adult deutocerebrum
definition: Region of the adult brain cell body rind that overlies the neuropil of the deutocerebrum.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2013-05-22T04:46:04Z
database_cross_reference: VFB:FBbt_00110410
has exact synonym: cell body rind of adult deuterocerebrum
has exact synonym: cortex of adult deuterocerebrum
has exact synonym: cortex of adult deutocerebrum
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110410

Axiom
annotated source: cell body rind of adult deutocerebrum
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the neuropil of the deutocerebrum.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

adult cerebral ganglion
type: Class
equivalent class: Class
  intersection of: supraesophageal ganglion
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: supraesophageal ganglion
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: adult brain
subclass of: Restriction
  on property: develops from
  some values from: larval brain
definition: The supraesophageal neuropils of the adult brain located above, around and partially below the esophagus, including the optic lobes. It excludes the gnathal ganglion. Developmentally, it comprises three fused neuromeres: protocerebrum, deutocerebrum, and tritocerebrum.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2013-10-08T17:05:57Z
database_cross_reference: UBERON:6110636
database_cross_reference: VFB:FBbt_00110636
has exact synonym: CRG
has OBO namespace: fly_anatomy.ontology
has related synonym: SPG
has related synonym: adult supraesophageal ganglion
has related synonym: brain
has related synonym: cerebrum
id: FBbt:00110636
in subset: BrainName
in subset: cur
comment: This term is related to what used to be called supraesophageal ganglion, and is now referred to as supraesophageal zone. The adult cerebral ganglion, together with the gnathal ganglia (GNG), denote regions that follow the segmental neuromeres of the brain (the 3 rostral and 3 caudal, respectively). These are distinguishable from supra- and subesophageal zones, as these refer to the neuropil masses above and below the esophagus and do not respect neuromere boundaries (Ito et al., 2014).

Axiom
annotated source: adult cerebral ganglion
annotated property: definition
annotated target: The supraesophageal neuropils of the adult brain located above, around and partially below the esophagus, including the optic lobes. It excludes the gnathal ganglion. Developmentally, it comprises three fused neuromeres: protocerebrum, deutocerebrum, and tritocerebrum.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult cerebral ganglion
annotated property: hasExactSynonym
annotated target: CRG
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

adult supraesophageal zone
type: Class
equivalent class: Class
  intersection of: supraesophageal zone
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: supraesophageal zone
subclass of: Restriction
  on property: part of
  some values from: adult cerebral ganglion
definition: Neuropil mass above the esophagus in the adult brain. It is part of the cerebral ganglion.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2013-10-08T17:07:47Z
database_cross_reference: VFB:FBbt_00110638
has exact synonym: SPZ
has narrow synonym: adult supraesophageal ganglion
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110638
in subset: BrainName
in subset: cur
comment: This term refers to what used to be called supraesophageal ganglion. The new name, together with subesophageal zone, refer to the neuropil masses above and below the esophagus and do not respect neuromere boundaries. The terms cerebral ganglia (CRG) and gnathal ganglia (GNG), denote regions that follow the segmental neuromeres of the brain (the 3 rostral and 3 caudal, respectively) (Ito et al., 2014).

Axiom
annotated source: adult supraesophageal zone
annotated property: definition
annotated target: Neuropil mass above the esophagus in the adult brain. It is part of the cerebral ganglion.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult supraesophageal zone
annotated property: hasExactSynonym
annotated target: SPZ
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

adult subesophageal zone
type: Class
equivalent class: Class
  intersection of: subesophageal zone
  intersection of: Restriction
    on property: overlaps
    some values from: adult
subclass of: subesophageal zone
subclass of: Restriction
  on property: part of
  some values from: adult central brain
definition: Neuropil mass below the esophagus in the adult brain. It encompasses the gnathal ganglion, the prow and the saddle.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2013-10-08T17:53:57Z
database_cross_reference: VFB:FBbt_00110639
has exact synonym: SEZ
has narrow synonym: SEG
has narrow synonym: SOG
has narrow synonym: adult subesophageal ganglion
has narrow synonym: adult suboesophageal ganglion
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110639
in subset: BrainName
in subset: cur
comment: This term refers to what used to be called subesophageal ganglion. The new name, together with supraesophageal zone, refer to the brain tissue below and above the esophagus and do not respect neuromere boundaries. The terms cerebral ganglia (CRG) and gnathal ganglia (GNG), denote the segmental neuromeres of the brain (the 3 rostral and 3 caudal, respectively) (Ito et al., 2014). Sterne et al. (2021) - FBrf0251280 define the SEZ as comprising GNG + TR.

Axiom
annotated source: adult subesophageal zone
annotated property: definition
annotated target: Neuropil mass below the esophagus in the adult brain. It encompasses the gnathal ganglion, the prow and the saddle.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: adult subesophageal zone
annotated property: hasExactSynonym
annotated target: SEZ
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

lobula columnar neuron LC10A
type: Class
subclass of: lobula columnar neuron LC10
IAO_0000028: LC10A
definition: Lobula columnar neuron LC10 subtype that enters the medial zone of the anterior optic tubercle (AOTU). There are 2 subtypes, which differ in their arborization in the lobula.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2014-10-21T14:15:18Z
database_cross_reference: VFB:FBbt_00110933
has exact synonym: LC10A
has exact synonym: Lcn10A
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110933

Axiom
annotated source: lobula columnar neuron LC10A
annotated property: definition
annotated target: Lobula columnar neuron LC10 subtype that enters the medial zone of the anterior optic tubercle (AOTU). There are 2 subtypes, which differ in their arborization in the lobula.
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0234700

Axiom
annotated source: lobula columnar neuron LC10A
annotated property: hasExactSynonym
annotated target: LC10A
has synonym type: VFB SYMBOL

lobula columnar neuron LC10B
type: Class
subclass of: lobula columnar neuron LC10
IAO_0000028: LC10B
definition: Lobula columnar neuron LC10 subtype whose axon fans out near the anterior optic tubercle (AOTU). It enters it in the medial region, along most of its dorsal/ventral axis.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2014-10-21T14:15:18Z
database_cross_reference: VFB:FBbt_00110934
has exact synonym: LC10B
has OBO namespace: fly_anatomy.ontology
id: FBbt:00110934

Axiom
annotated source: lobula columnar neuron LC10B
annotated property: definition
annotated target: Lobula columnar neuron LC10 subtype whose axon fans out near the anterior optic tubercle (AOTU). It enters it in the medial region, along most of its dorsal/ventral axis.
database_cross_reference: FlyBase:FBrf0193607
database_cross_reference: FlyBase:FBrf0234700

Axiom
annotated source: lobula columnar neuron LC10B
annotated property: hasExactSynonym
annotated target: LC10B
has synonym type: VFB SYMBOL

cell body rind of adult optic lobe
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: adult optic lobe
subclass of: Restriction
  on property: part of
  some values from: cell body rind of adult protocerebrum
definition: Region of the adult brain cell body rind that overlies the neuropil of the optic lobe. It includes the regions that overlie the lamina, medulla, lobula and lobula plate.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-08-07T12:03:01Z
database_cross_reference: VFB:FBbt_00111152
has exact synonym: OLBR
has exact synonym: cortex of optic lobe
has exact synonym: optic lobe cell body rind
has exact synonym: rOL
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111152

Axiom
annotated source: cell body rind of adult optic lobe
annotated property: definition
annotated target: Region of the adult brain cell body rind that overlies the neuropil of the optic lobe. It includes the regions that overlie the lamina, medulla, lobula and lobula plate.
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult optic lobe
annotated property: hasExactSynonym
annotated target: OLBR
database_cross_reference: FlyBase:FBrf0224194
has synonym type: BRAIN NAME ABV

Axiom
annotated source: cell body rind of adult optic lobe
annotated property: hasExactSynonym
annotated target: optic lobe cell body rind
database_cross_reference: FlyBase:FBrf0224194

Axiom
annotated source: cell body rind of adult optic lobe
annotated property: hasExactSynonym
annotated target: rOL
database_cross_reference: FlyBase:FBrf0224194

embryonic/larval anterior optic tubercle primordial
type: Class
subclass of: primordium
subclass of: Restriction
  on property: part of
  some values from: larval superior protocerebrum
subclass of: Restriction
  on property: develops into
  some values from: anterior optic tubercle
definition: The primordium of the adult anterior optic tubercle (AOTU) in the larval anterior protocerebrum, laterally adjacent to the vertical lobe of the mushroom body (Lovick et al., 2017). It is initially a small, homogenous, hemispherical domain containing the distal filopodia of afferent optic lobe interneurons and the proximal filopodia of DALcl1/2 dorsal hemilineages (Lovick et al., 2017). During metamorphosis, the different subcompartments of the adult AOTU become distinct (Lovick et al., 2017).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-09-15T16:59:51Z
has broad synonym: CPLd
database_cross_reference: VFB:FBbt_00111205
database_cross_reference: larvalbrain_neuropil:396
database_cross_reference: larvalbrain_neuropil:574
has exact synonym: larval AOTU
has exact synonym: larval primordium of the AOTU
has exact synonym: prAOTU
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111205

Axiom
annotated source: embryonic/larval anterior optic tubercle primordial
annotated property: definition
annotated target: The primordium of the adult anterior optic tubercle (AOTU) in the larval anterior protocerebrum, laterally adjacent to the vertical lobe of the mushroom body (Lovick et al., 2017). It is initially a small, homogenous, hemispherical domain containing the distal filopodia of afferent optic lobe interneurons and the proximal filopodia of DALcl1/2 dorsal hemilineages (Lovick et al., 2017). During metamorphosis, the different subcompartments of the adult AOTU become distinct (Lovick et al., 2017).
database_cross_reference: FlyBase:FBrf0236656

Axiom
annotated source: embryonic/larval anterior optic tubercle primordial
annotated property: hasBroadSynonym
annotated target: CPLd
database_cross_reference: FlyBase:FBrf0229672

Axiom
annotated source: embryonic/larval anterior optic tubercle primordial
annotated property: hasExactSynonym
annotated target: larval primordium of the AOTU
database_cross_reference: FlyBase:FBrf0236656

Axiom
annotated source: embryonic/larval anterior optic tubercle primordial
annotated property: hasExactSynonym
annotated target: prAOTU
database_cross_reference: FlyBase:FBrf0236656

cell body rind of larval brain
type: Class
subclass of: cell body rind region
subclass of: Restriction
  on property: part of
  some values from: larval brain
subclass of: Restriction
  on property: part of
  some values from: cell body rind of larval central nervous system
definition: Region of the larval cell body rind that overlies the neuropil of the brain.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-10-29T11:43:24Z
database_cross_reference: VFB:FBbt_00111226
has exact synonym: cortex of larval brain
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111226

Axiom
annotated source: cell body rind of larval brain
annotated property: definition
annotated target: Region of the larval cell body rind that overlies the neuropil of the brain.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

medulla sublayer M3A
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: medulla layer M3
definition: Distal sublayer of the medulla layer M3, proximal to layer M2. It is defined by the extent of the arborization of Dm3 neurons.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-10T14:00:27Z
database_cross_reference: VFB:FBbt_00111267
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111267
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla sublayer M3A
annotated property: definition
annotated target: Distal sublayer of the medulla layer M3, proximal to layer M2. It is defined by the extent of the arborization of Dm3 neurons.
database_cross_reference: FlyBase:FBrf0228639

medulla sublayer M3B
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: medulla layer M3
definition: Proximal sublayer of the medulla layer M3, proximal to layer M3A. It is defined by the extent of the arborization of Dm12 and Dm20 neurons.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-10T14:00:27Z
database_cross_reference: VFB:FBbt_00111268
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111268
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and medial-lateral (e.g. Ito et al., 2014), both meaning outer and inner, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla sublayer M3B
annotated property: definition
annotated target: Proximal sublayer of the medulla layer M3, proximal to layer M3A. It is defined by the extent of the arborization of Dm12 and Dm20 neurons.
database_cross_reference: FlyBase:FBrf0228639

medulla sublayer M6A
type: Class
subclass of: medulla layer
subclass of: Restriction
  on property: part of
  some values from: medulla layer M6
definition: Distal sublayer of the medulla layer M6, proximal to layer M5. It is defined by the extent of the arborization of Dm8 neurons proximally.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-10T14:00:27Z
database_cross_reference: VFB:FBbt_00111269
has exact synonym: M6M
has exact synonym: medial half of the M6 layer
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111269
in subset: cur
comment: In the literature there are two methods for describing spatial location of neurons in the visual system: distal-proximal (e.g. Fischbach and Dittrich, 1989), and lateral-medial (e.g. Ito et al., 2014), both meaning outer and inner, respectively, and refer to the distance of a structure along the visual pathway relative to the center of the brain. Currently we will adopt the classical 'distal-proximal'.

Axiom
annotated source: medulla sublayer M6A
annotated property: definition
annotated target: Distal sublayer of the medulla layer M6, proximal to layer M5. It is defined by the extent of the arborization of Dm8 neurons proximally.
database_cross_reference: FlyBase:FBrf0228639

Axiom
annotated source: medulla sublayer M6A
annotated property: hasExactSynonym
annotated target: M6M
database_cross_reference: FlyBase:FBrf0224242

Axiom
annotated source: medulla sublayer M6A
annotated property: hasExactSynonym
annotated target: medial half of the M6 layer
database_cross_reference: FlyBase:FBrf0224242

distal medullary amacrine neuron Dm9
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm9
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla sublayer M6A
IAO_0000028: Dm9
definition: Distal medullary wide-field amacrine neuron with arbors that span multiple columns in layers M1 and M6A and columnar processes between these two layers. The processes in M2 and M5 occupy a central column position and are closely associated with R7 and R8 photoreceptor axons, covering around 7 columns. There are around 110 Dm9 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-10T14:00:27Z
database_cross_reference: VFB:FBbt_00111271
has exact synonym: Dm9
has exact synonym: glia-like cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111271
in subset: cur

Axiom
annotated source: distal medullary amacrine neuron Dm9
annotated property: IAO_0000028
annotated target: Dm9
database_cross_reference: FlyBase:FBrf0225846
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm9
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron with arbors that span multiple columns in layers M1 and M6A and columnar processes between these two layers. The processes in M2 and M5 occupy a central column position and are closely associated with R7 and R8 photoreceptor axons, covering around 7 columns. There are around 110 Dm9 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: distal medullary amacrine neuron Dm9
annotated property: hasExactSynonym
annotated target: Dm9
database_cross_reference: FlyBase:FBrf0225846
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

Axiom
annotated source: distal medullary amacrine neuron Dm9
annotated property: hasExactSynonym
annotated target: glia-like cell
database_cross_reference: FlyBase:FBrf0206213

distal medullary amacrine neuron Dm11
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm11
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla sublayer M6A
IAO_0000028: Dm11
definition: Distal medullary wide-field amacrine neuron whose cell body is located in the dorsal region of the cell body rind of the medulla. Its primary neurite extends beyond M6A layer, and then turns back, forming recurrent, columnar processes from M6A to M1, and into the first optic chiasm. The arbor varies in shape between cells, covering around 9 columns and showing tiling. The terminals of these cells in M6A collectively occupy the whole layer, whereas in the other layers the processes are thin, with each process occupying only one column, and being associated with R7 and R8 photoreceptor axons. There are around 70 Dm11 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-10T14:00:27Z
database_cross_reference: VFB:FBbt_00111272
has exact synonym: Dm11
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111272
in subset: cur

Axiom
annotated source: distal medullary amacrine neuron Dm11
annotated property: IAO_0000028
annotated target: Dm11
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm11
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron whose cell body is located in the dorsal region of the cell body rind of the medulla. Its primary neurite extends beyond M6A layer, and then turns back, forming recurrent, columnar processes from M6A to M1, and into the first optic chiasm. The arbor varies in shape between cells, covering around 9 columns and showing tiling. The terminals of these cells in M6A collectively occupy the whole layer, whereas in the other layers the processes are thin, with each process occupying only one column, and being associated with R7 and R8 photoreceptor axons. There are around 70 Dm11 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: distal medullary amacrine neuron Dm11
annotated property: hasExactSynonym
annotated target: Dm11
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

distal medullary amacrine neuron Dm12
type: Class
subclass of: distal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult glutamatergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature distal medullary amacrine neuron Dm12
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla sublayer M3B
IAO_0000028: Dm12
definition: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. Its primary neurite extends into the M6 layer, and then turns back to project to M3B. The arbor is circular in shape, overlapping and covering around 15-20 columns. The arbor is located in a peripheral intracolumnar position. There are around 120 Dm12 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-10T14:00:27Z
database_cross_reference: VFB:FBbt_00111273
has exact synonym: Dm12
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111273
in subset: cur

Axiom
annotated source: distal medullary amacrine neuron Dm12
annotated property: IAO_0000028
annotated target: Dm12
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: distal medullary amacrine neuron Dm12
annotated property: definition
annotated target: Distal medullary wide-field amacrine neuron whose cell body is located in the cell body rind of the medulla. Its primary neurite extends into the M6 layer, and then turns back to project to M3B. The arbor is circular in shape, overlapping and covering around 15-20 columns. The arbor is located in a peripheral intracolumnar position. There are around 120 Dm12 neurons per hemisphere. They are glutamatergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0244935

Axiom
annotated source: distal medullary amacrine neuron Dm12
annotated property: hasExactSynonym
annotated target: Dm12
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

proximal medullary amacrine neuron Pm4
type: Class
subclass of: adult optic lobe neuron
subclass of: proximal medullary amacrine neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult GABAergic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
subclass of: Restriction
  on property: develops from
  some values from: immature proximal medullary amacrine neuron Pm4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M8
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M9
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M8
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M9
IAO_0000028: Pm4
definition: Proximal medullary amacrine neuron that branches at the proximal surface of the medulla. It covers around 10-20 columns with its pre- and post-synapses mostly in layers M8-M9 (Nern et al., 2025). It occupies a central intracolumnar position. It is GABAergic (Davis et al., 2020). There are around 75-85 of these neurons per hemisphere (Nern et al., 2025).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-10T14:48:20Z
database_cross_reference: VFB:FBbt_00111282
has exact synonym: Pm05
has exact synonym: Pm4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111282
in subset: cur

Axiom
annotated source: proximal medullary amacrine neuron Pm4
annotated property: IAO_0000028
annotated target: Pm4
database_cross_reference: FlyBase:FBrf0228639

Axiom
annotated source: proximal medullary amacrine neuron Pm4
annotated property: definition
annotated target: Proximal medullary amacrine neuron that branches at the proximal surface of the medulla. It covers around 10-20 columns with its pre- and post-synapses mostly in layers M8-M9 (Nern et al., 2025). It occupies a central intracolumnar position. It is GABAergic (Davis et al., 2020). There are around 75-85 of these neurons per hemisphere (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0228639
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: proximal medullary amacrine neuron Pm4
annotated property: hasExactSynonym
annotated target: Pm05
database_cross_reference: FlyBase:FBrf0260545
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: proximal medullary amacrine neuron Pm4
annotated property: hasExactSynonym
annotated target: Pm4
database_cross_reference: FlyBase:FBrf0228639
has synonym type: VFB SYMBOL

medulla intrinsic neuron Mi15
type: Class
subclass of: medulla intrinsic columnar neuron
subclass of: Notch OFF hemilineage secondary neuron
subclass of: adult cholinergic neuron
subclass of: adult dopaminergic neuron
subclass of: optic lobe narrow field columnar neuron
subclass of: Restriction
  on property: develops from
  some values from: immature medulla intrinsic neuron Mi15
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M1
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M2
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M4
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M5
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla serpentine layer
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: inner photoreceptor cell
IAO_0000028: Mi15
definition: Medulla intrinsic unicolumnar neuron whose primary neurite splits in the M1 layer, sending vertical branches as far as the M7 layer (Takemura et al., 2013; Takemura et al., 2015; Kind et al., 2021). A process also extends from the distal medulla into the first optic chiasma, where it receives around half of its photoreceptor input (Kind et al., 2021). In central columns, these cells selectively receive input from R8, rather than R7 photoreceptors, but selectivity is not maintained in Mi15 cells of the dorsal rim area (Kind et al., 2021). It seems to be both cholinergic and dopaminergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-10T17:28:29Z
database_cross_reference: VFB:FBbt_00111285
has exact synonym: Mi15
has exact synonym: medullary intrinsic neuron Mi15
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111285
in subset: cur

Axiom
annotated source: medulla intrinsic neuron Mi15
annotated property: IAO_0000028
annotated target: Mi15
database_cross_reference: FlyBase:FBrf0247762

Axiom
annotated source: medulla intrinsic neuron Mi15
annotated property: definition
annotated target: Medulla intrinsic unicolumnar neuron whose primary neurite splits in the M1 layer, sending vertical branches as far as the M7 layer (Takemura et al., 2013; Takemura et al., 2015; Kind et al., 2021). A process also extends from the distal medulla into the first optic chiasma, where it receives around half of its photoreceptor input (Kind et al., 2021). In central columns, these cells selectively receive input from R8, rather than R7 photoreceptors, but selectivity is not maintained in Mi15 cells of the dorsal rim area (Kind et al., 2021). It seems to be both cholinergic and dopaminergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0222324
database_cross_reference: FlyBase:FBrf0230092
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: medulla intrinsic neuron Mi15
annotated property: hasExactSynonym
annotated target: Mi15
database_cross_reference: FlyBase:FBrf0247762
has synonym type: VFB SYMBOL

lobula plate intrinsic neuron LPi3-4
type: Class
subclass of: adult optic lobe neuron
subclass of: lobula plate intrinsic neuron
subclass of: adult glutamatergic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult medulla
subclass of: Restriction
  on property: overlaps
  some values from: second optic chiasma
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula plate layer 3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula plate layer 4
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: T4c neuron
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: T5c neuron
IAO_0000028: LPi3-4
definition: Lobula plate intrinsic neuron with its soma in the cell body rind of the medulla (Mauss et al., 2015; Shinomiya et al., 2019). The primary neurite traverses the medulla, from distal to proximal and crosses the second optic chiasm, to terminate in the lobula plate (Mauss et al., 2015; Shinomiya et al., 2019). It has presynaptic terminals in layer 4 and postsynaptic ones in layer 3 (Mauss et al., 2015; Shinomiya et al., 2019). It receives most of its input from T4c and T5c neurons (Shinomiya et al., 2022). It is a glutamatergic neuron (Mauss et al., 2015). There are around 55-60 of these cells on each side (Nern et al., 2025).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2015-11-11T14:58:39Z
database_cross_reference: VFB:FBbt_00111289
has exact synonym: CB3857
has exact synonym: LPi09
has exact synonym: LPi3-4
has exact synonym: LPi34
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111289
comment: The glutamate neurotransmitter was assessed by antibody staining and mRNA profiling (Mauss et al., 2015). Matsliah et al. (2024) - FBrf0260545 nomenclature scheme unrelated to layer innervation.

Axiom
annotated source: lobula plate intrinsic neuron LPi3-4
annotated property: IAO_0000028
annotated target: LPi3-4
database_cross_reference: FlyBase:FBrf0228988

Axiom
annotated source: lobula plate intrinsic neuron LPi3-4
annotated property: definition
annotated target: Lobula plate intrinsic neuron with its soma in the cell body rind of the medulla (Mauss et al., 2015; Shinomiya et al., 2019). The primary neurite traverses the medulla, from distal to proximal and crosses the second optic chiasm, to terminate in the lobula plate (Mauss et al., 2015; Shinomiya et al., 2019). It has presynaptic terminals in layer 4 and postsynaptic ones in layer 3 (Mauss et al., 2015; Shinomiya et al., 2019). It receives most of its input from T4c and T5c neurons (Shinomiya et al., 2022). It is a glutamatergic neuron (Mauss et al., 2015). There are around 55-60 of these cells on each side (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0228988
database_cross_reference: FlyBase:FBrf0243899
database_cross_reference: FlyBase:FBrf0254308
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lobula plate intrinsic neuron LPi3-4
annotated property: hasExactSynonym
annotated target: CB3857
database_cross_reference: FlyBase:FBrf0260535
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lobula plate intrinsic neuron LPi3-4
annotated property: hasExactSynonym
annotated target: LPi09
database_cross_reference: FlyBase:FBrf0260545
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: lobula plate intrinsic neuron LPi3-4
annotated property: hasExactSynonym
annotated target: LPi3-4
database_cross_reference: FlyBase:FBrf0228988
has synonym type: VFB SYMBOL

Axiom
annotated source: lobula plate intrinsic neuron LPi3-4
annotated property: hasExactSynonym
annotated target: LPi34
database_cross_reference: FlyBase:FBrf0262545

intrinsic wedge neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: wedge
subclass of: adult central brain intrinsic neuron
subclass of: Restriction
  on property: part of
  some values from: adult brain
subclass of: Restriction
  on property: synapses restricted to region
  some values from: wedge
definition: Interneuron that innervates only the adult wedge.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2016-01-07T15:23:13Z
database_cross_reference: VFB:FBbt_00111353
has exact synonym: IVLP LN
has exact synonym: intrinsic IVLP neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111353
in subset: cur

Axiom
annotated source: intrinsic wedge neuron
annotated property: definition
annotated target: Interneuron that innervates only the adult wedge.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

intrinsic ventrolateral protocerebrum neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: synapses restricted to region
    some values from: ventrolateral protocerebrum
subclass of: adult central brain intrinsic neuron
subclass of: Restriction
  on property: part of
  some values from: adult brain
subclass of: Restriction
  on property: synapses restricted to region
  some values from: ventrolateral protocerebrum
definition: Neuron that innervates the ventrolateral protocerebrum region only.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2016-01-07T15:37:37Z
database_cross_reference: VFB:FBbt_00111360
has exact synonym: VLP LN
has exact synonym: intrinsic VLP neuron
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111360

Axiom
annotated source: intrinsic ventrolateral protocerebrum neuron
annotated property: definition
annotated target: Neuron that innervates the ventrolateral protocerebrum region only.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

lobula intrinsic neuron Li4
type: Class
subclass of: adult optic lobe neuron
subclass of: lobula intrinsic neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult lobula
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 4
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 5
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: transmedullary neuron Tm20
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: transmedullary neuron Tm5a
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: transmedullary neuron Tm5b
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: transmedullary neuron Tm5c
IAO_0000028: Li4
definition: Neuron whose cell body lies in the cortex of the lobula. It arborizes over a large area of the lobula, mostly in layer 5 but with some branches in layer 4. It receives very strong synaptic input from Tm5a/b/c and Tm20 neurons (Lin et al., 2016). There are approximately 30 of these cells per hemisphere (Lin et al., 2016).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2016-03-17T15:25:01Z
database_cross_reference: VFB:FBbt_00111516
has exact synonym: Li4
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111516
in subset: cur
comment: Connectivity data was assessed by GRASP and double-labeling EM (Lin et al., 2016).

Axiom
annotated source: lobula intrinsic neuron Li4
annotated property: IAO_0000028
annotated target: Li4
database_cross_reference: FlyBase:FBrf0230403

Axiom
annotated source: lobula intrinsic neuron Li4
annotated property: definition
annotated target: Neuron whose cell body lies in the cortex of the lobula. It arborizes over a large area of the lobula, mostly in layer 5 but with some branches in layer 4. It receives very strong synaptic input from Tm5a/b/c and Tm20 neurons (Lin et al., 2016). There are approximately 30 of these cells per hemisphere (Lin et al., 2016).
database_cross_reference: FlyBase:FBrf0230403

Axiom
annotated source: lobula intrinsic neuron Li4
annotated property: hasExactSynonym
annotated target: Li4
database_cross_reference: FlyBase:FBrf0230403
has synonym type: VFB SYMBOL

medulla columnar neuron
type: Class
subclass of: adult optic lobe columnar neuron
subclass of: adult visual projection neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: medulla
IAO_0000028: MC
definition: An extrinsic columnar neuron that innervates the medulla.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2016-05-26T17:57:24Z
database_cross_reference: VFB:FBbt_00111640
has exact synonym: MC
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111640
in subset: cur

Axiom
annotated source: medulla columnar neuron
annotated property: IAO_0000028
annotated target: MC
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: medulla columnar neuron
annotated property: definition
annotated target: An extrinsic columnar neuron that innervates the medulla.
database_cross_reference: FlyBase:FBrf0224242

Axiom
annotated source: medulla columnar neuron
annotated property: hasExactSynonym
annotated target: MC
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

embryonic/larval lateral horn
type: Class
subclass of: synaptic neuropil subdomain
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval superior lateral protocerebrum
definition: Subregion of the larval superior lateral protocerebrum (CPLd) that will give rise to the adult lateral horn. It is defined by the axonal arbors of the olfactory uniglomerular projection neurons.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2016-10-13T14:51:07Z
database_cross_reference: VFB:FBbt_00111688
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111688

Axiom
annotated source: embryonic/larval lateral horn
annotated property: definition
annotated target: Subregion of the larval superior lateral protocerebrum (CPLd) that will give rise to the adult lateral horn. It is defined by the axonal arbors of the olfactory uniglomerular projection neurons.
database_cross_reference: FlyBase:FBrf0211016
database_cross_reference: FlyBase:FBrf0220443

optic lobe neuroepithelial cell
type: Class
subclass of: somatic stem cell
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: embryonic/larval optic lobe
subclass of: Restriction
  on property: develops from
  some values from: embryonic optic lobe primordium
definition: Symmetrically-dividing stem cell with epithelial properties and a columnar morphology that is a precursor to an optic neuroblast (Egger et al., 2007). These cells increase in number by symmetric divisions during embryonic and larval development (Egger et al., 2007). A small number differentiate into optic neuroblasts during the embryonic stage, while the remainder enter G0 quiescence prior to larval hatching (Hakes et al., 2018). Divisions resume in the first instar (Hakes et al., 2018), followed by differentiation to neuroblasts mainly during the third instar stage (Yasugi et al., 2008).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-01-30T17:06:45Z
database_cross_reference: VFB:FBbt_00111738
has exact synonym: optic lobe NE cell
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111738

Axiom
annotated source: optic lobe neuroepithelial cell
annotated property: definition
annotated target: Symmetrically-dividing stem cell with epithelial properties and a columnar morphology that is a precursor to an optic neuroblast (Egger et al., 2007). These cells increase in number by symmetric divisions during embryonic and larval development (Egger et al., 2007). A small number differentiate into optic neuroblasts during the embryonic stage, while the remainder enter G0 quiescence prior to larval hatching (Hakes et al., 2018). Divisions resume in the first instar (Hakes et al., 2018), followed by differentiation to neuroblasts mainly during the third instar stage (Yasugi et al., 2008).
database_cross_reference: FlyBase:FBrf0193624
database_cross_reference: FlyBase:FBrf0204205
database_cross_reference: FlyBase:FBrf0240123

Axiom
annotated source: optic lobe neuroepithelial cell
annotated property: hasExactSynonym
annotated target: optic lobe NE cell
database_cross_reference: FlyBase:FBrf0204205

lobula layer 5A
type: Class
subclass of: lobula layer
subclass of: Restriction
  on property: part of
  some values from: lobula layer 5
definition: Sublayer of the lobula layer 5 that is most proximal to layer 4.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-04-28T16:08:36Z
database_cross_reference: VFB:FBbt_00111743
has exact synonym: lobula layer Lo5A
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111743
comment: This layer was identified by Brp staining (Wu et al., 2016).

Axiom
annotated source: lobula layer 5A
annotated property: definition
annotated target: Sublayer of the lobula layer 5 that is most proximal to layer 4.
database_cross_reference: FlyBase:FBrf0234700

Axiom
annotated source: lobula layer 5A
annotated property: hasExactSynonym
annotated target: lobula layer Lo5A
database_cross_reference: FlyBase:FBrf0234700

lobula layer 5B
type: Class
subclass of: lobula layer
subclass of: Restriction
  on property: part of
  some values from: lobula layer 5
definition: Sublayer of the lobula layer 5 that is most proximal to layer 6.
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-04-28T16:08:36Z
database_cross_reference: VFB:FBbt_00111744
has exact synonym: lobula layer Lo5B
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111744
comment: This layer was identified by Brp staining (Wu et al., 2016).

Axiom
annotated source: lobula layer 5B
annotated property: definition
annotated target: Sublayer of the lobula layer 5 that is most proximal to layer 6.
database_cross_reference: FlyBase:FBrf0234700

Axiom
annotated source: lobula layer 5B
annotated property: hasExactSynonym
annotated target: lobula layer Lo5B
database_cross_reference: FlyBase:FBrf0234700

lobula columnar neuron LC10b
type: Class
subclass of: adult cholinergic neuron
subclass of: lobula columnar neuron LC10A
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula layer 6
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 5A
IAO_0000028: LC10b
definition: Subtype of lobula columnar neuron LC10A. It has its main arbors in lobula layers 4 to 6, with arbors denser in the latter, and many parallel processes exist between the two layers. Presynaptic sites are mainly observed in layer 6, with some in layers 4 and 5A. It is a cholinergic neuron (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-04-28T16:08:36Z
database_cross_reference: VFB:FBbt_00111745
has exact synonym: LC10b
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111745
comment: Pre- versus postsynaptic innervation assessed with a presynaptic marker (synaptotagmin-HA driver) (Wu et al., 2016).

Axiom
annotated source: lobula columnar neuron LC10b
annotated property: IAO_0000028
annotated target: LC10b
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula columnar neuron LC10b
annotated property: definition
annotated target: Subtype of lobula columnar neuron LC10A. It has its main arbors in lobula layers 4 to 6, with arbors denser in the latter, and many parallel processes exist between the two layers. Presynaptic sites are mainly observed in layer 6, with some in layers 4 and 5A. It is a cholinergic neuron (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0244935

Axiom
annotated source: lobula columnar neuron LC10b
annotated property: hasExactSynonym
annotated target: LC10b
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

lobula columnar neuron LC10a
type: Class
subclass of: adult cholinergic neuron
subclass of: lobula columnar neuron LC10B
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula layer 3
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 6
IAO_0000028: LC10a
definition: Subtype of lobula columnar neuron LC10B. It has its main arbors in lobula layers 3, 4 and 5B, with some processes extending into layer 2 and some branches in layers 5 and 6. Presynaptic sites are observed in layer 3. It is a cholinergic neuron (Davis et al., 2020). It is involved in the detection of fly-sized objects and its sensitivity increases during male courtship or female aggression (Schretter et al., 2025).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-04-28T16:08:36Z
database_cross_reference: VFB:FBbt_00111747
has exact synonym: LC10a
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111747
comment: Pre- versus postsynaptic innervation assessed with a presynaptic marker (synaptotagmin-HA driver) (Wu et al., 2016).

Axiom
annotated source: lobula columnar neuron LC10a
annotated property: IAO_0000028
annotated target: LC10a
database_cross_reference: FlyBase:FBrf0246888

Axiom
annotated source: lobula columnar neuron LC10a
annotated property: definition
annotated target: Subtype of lobula columnar neuron LC10B. It has its main arbors in lobula layers 3, 4 and 5B, with some processes extending into layer 2 and some branches in layers 5 and 6. Presynaptic sites are observed in layer 3. It is a cholinergic neuron (Davis et al., 2020). It is involved in the detection of fly-sized objects and its sensitivity increases during male courtship or female aggression (Schretter et al., 2025).
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0261440

Axiom
annotated source: lobula columnar neuron LC10a
annotated property: hasExactSynonym
annotated target: LC10a
database_cross_reference: FlyBase:FBrf0246888
has synonym type: VFB SYMBOL

lobula plate-lobula columnar neuron LPLC1
type: Class
subclass of: lobula plate-lobula columnar neuron LPLC
subclass of: adult cholinergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula layer 3
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 2
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5A
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5B
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: LPLC1 optic glomerulus
IAO_0000028: LPLC1
definition: Lobula plate-lobula columnar neuron whose cell body lies in the dorsal area of the lateral cell body rind (Wu et al., 2016). Its processes extend the full depth of the lobula plate, being sparser in layer 1 (Wu et al., 2016). In the lobula, its main dendritic arbors are in layers 2-5B (Wu et al., 2016; Tanaka and Clark, 2022). Presynaptic sites are observed in the boundary of lobula layers 3/4 (Wu et al., 2016). Its arbors span approximately 25 lobula optic columns, overlapping with other LPLC1 cells (Wu et al., 2016). It projects to a posterior optic glomerulus of the PVLP, at the boundary with the PLP (Wu et al., 2016). There are around 62 cells of this type (Wu et al., 2016). They are cholinergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-04-28T16:08:36Z
database_cross_reference: VFB:FBbt_00111762
has exact synonym: LPLC1
has exact synonym: lobula complex columnar neuron LPLC1
has exact synonym: lobula plate and lobula columnar neuron 1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111762
comment: Pre- versus postsynaptic innervation assessed with a presynaptic marker (synaptotagmin-HA driver) (Wu et al., 2016).

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC1
annotated property: definition
annotated target: Lobula plate-lobula columnar neuron whose cell body lies in the dorsal area of the lateral cell body rind (Wu et al., 2016). Its processes extend the full depth of the lobula plate, being sparser in layer 1 (Wu et al., 2016). In the lobula, its main dendritic arbors are in layers 2-5B (Wu et al., 2016; Tanaka and Clark, 2022). Presynaptic sites are observed in the boundary of lobula layers 3/4 (Wu et al., 2016). Its arbors span approximately 25 lobula optic columns, overlapping with other LPLC1 cells (Wu et al., 2016). It projects to a posterior optic glomerulus of the PVLP, at the boundary with the PLP (Wu et al., 2016). There are around 62 cells of this type (Wu et al., 2016). They are cholinergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0233032
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0253297

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC1
annotated property: hasExactSynonym
annotated target: LPLC1
has synonym type: VFB SYMBOL

lobula plate-lobula columnar neuron LPLC2
type: Class
subclass of: lobula plate-lobula columnar neuron LPLC
subclass of: adult cholinergic neuron
subclass of: optic lobe wide-field columnar neuron
subclass of: Restriction
  on property: capable of part of
  some values from: GO_0007630
subclass of: Restriction
  on property: has synaptic IO in region
  some values from: lobula layer 4
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: LPLC2 optic glomerulus
IAO_0000028: LPLC2
definition: Lobula plate-lobula columnar neuron whose cell body lies in the dorsal area of the lateral cell body rind (Wu et al., 2016). It has a distinct dendritic arbor in each lobula plate layer, extending outwards from the main fiber in the direction of motion detection for the layer (Klapoetke et al., 2017). This arrangement allows it to detect looming (expansion) stimuli (Klapoetke et al., 2017). In the lobula, it has its main dendritic arbors in layers 4 and 5B, with minor processes in layer 5A, and presynaptic sites in layer 4 (Wu et al., 2016; Tanaka and Clark, 2022). Its arbors span approximately 25 lobula optic columns, overlapping with other LPLC2 cells (Wu et al., 2016). It projects to an optic glomerulus of the PVLP, anterior to LPLC1 and dorsal to LC4 (Wu et al., 2016). Its activity elicits a jump escape response (Wu et al., 2016; Klapoetke et al., 2017). There are approximately 80 of these cells per optic lobe (Wu et al., 2016) and they are cholinergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-04-28T16:08:36Z
database_cross_reference: VFB:FBbt_00111763
has exact synonym: LPL2CN
has exact synonym: LPLC2
has exact synonym: lobula complex columnar neuron LPLC2
has exact synonym: lobula plate and lobula columnar neuron 2
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111763
comment: Pre- versus postsynaptic innervation assessed with a presynaptic marker (synaptotagmin-HA driver) (Wu et al., 2016).

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC2
annotated property: definition
annotated target: Lobula plate-lobula columnar neuron whose cell body lies in the dorsal area of the lateral cell body rind (Wu et al., 2016). It has a distinct dendritic arbor in each lobula plate layer, extending outwards from the main fiber in the direction of motion detection for the layer (Klapoetke et al., 2017). This arrangement allows it to detect looming (expansion) stimuli (Klapoetke et al., 2017). In the lobula, it has its main dendritic arbors in layers 4 and 5B, with minor processes in layer 5A, and presynaptic sites in layer 4 (Wu et al., 2016; Tanaka and Clark, 2022). Its arbors span approximately 25 lobula optic columns, overlapping with other LPLC2 cells (Wu et al., 2016). It projects to an optic glomerulus of the PVLP, anterior to LPLC1 and dorsal to LC4 (Wu et al., 2016). Its activity elicits a jump escape response (Wu et al., 2016; Klapoetke et al., 2017). There are approximately 80 of these cells per optic lobe (Wu et al., 2016) and they are cholinergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0233032
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0237184
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0253297

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC2
annotated property: hasExactSynonym
annotated target: LPL2CN
database_cross_reference: FlyBase:FBrf0218239

Axiom
annotated source: lobula plate-lobula columnar neuron LPLC2
annotated property: hasExactSynonym
annotated target: LPLC2
has synonym type: VFB SYMBOL

lobula plate columnar neuron
type: Class
subclass of: adult optic lobe neuron
subclass of: adult optic lobe columnar neuron
subclass of: adult visual projection neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult lobula plate
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula
IAO_0000028: LPC
definition: Columnar visual projection neuron with its soma in the cell body rind of the lobula plate (Shinomiya et al., 2022). It receives input in the lobula plate (but no other optic neuropil regions) and projects along a path posterior to the lobula plate to the central brain (Shinomiya et al., 2022).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-04-28T16:08:36Z
database_cross_reference: VFB:FBbt_00111766
has exact synonym: LPC
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111766
in subset: cur

Axiom
annotated source: lobula plate columnar neuron
annotated property: IAO_0000028
annotated target: LPC
database_cross_reference: FlyBase:FBrf0233032
database_cross_reference: FlyBase:FBrf0234700

Axiom
annotated source: lobula plate columnar neuron
annotated property: definition
annotated target: Columnar visual projection neuron with its soma in the cell body rind of the lobula plate (Shinomiya et al., 2022). It receives input in the lobula plate (but no other optic neuropil regions) and projects along a path posterior to the lobula plate to the central brain (Shinomiya et al., 2022).
database_cross_reference: FlyBase:FBrf0049410
database_cross_reference: FlyBase:FBrf0254308

Axiom
annotated source: lobula plate columnar neuron
annotated property: hasExactSynonym
annotated target: LPC
database_cross_reference: FlyBase:FBrf0233032
database_cross_reference: FlyBase:FBrf0234700
has synonym type: VFB SYMBOL

lobula plate columnar neuron LPC1
type: Class
subclass of: adult cholinergic neuron
subclass of: lobula plate columnar neuron
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula plate layer 2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: optic glomerulus of the PVLP
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: T4b neuron
subclass of: Restriction
  on property: receives synaptic input from neuron
  some values from: T5b neuron
IAO_0000028: LPC1
definition: Lobula plate columnar neuron that has its main dendritic arborization in lobula plate layer 2 and receives input from T4b and T5b neurons (Shinomiya et al., 2022). It projects to a small glomerulus in the posterior region of the optic glomeruli of the PVLP, posterior to LC4 and ventral to LPLC3. It is cholinergic (Davis et al., 2020).
contributor: https://orcid.org/0000-0001-5948-3092
date: 2017-04-28T16:08:36Z
database_cross_reference: VFB:FBbt_00111767
has exact synonym: LPC1
has OBO namespace: fly_anatomy.ontology
id: FBbt:00111767

Axiom
annotated source: lobula plate columnar neuron LPC1
annotated property: IAO_0000028
annotated target: LPC1
database_cross_reference: FlyBase:FBrf0254308

Axiom
annotated source: lobula plate columnar neuron LPC1
annotated property: definition
annotated target: Lobula plate columnar neuron that has its main dendritic arborization in lobula plate layer 2 and receives input from T4b and T5b neurons (Shinomiya et al., 2022). It projects to a small glomerulus in the posterior region of the optic glomeruli of the PVLP, posterior to LC4 and ventral to LPLC3. It is cholinergic (Davis et al., 2020).
database_cross_reference: FlyBase:FBrf0233032
database_cross_reference: FlyBase:FBrf0234700
database_cross_reference: FlyBase:FBrf0244935
database_cross_reference: FlyBase:FBrf0254308

Axiom
annotated source: lobula plate columnar neuron LPC1
annotated property: hasExactSynonym
annotated target: LPC1
database_cross_reference: FlyBase:FBrf0254308
has synonym type: VFB SYMBOL

anterior ectoderm anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: Restriction
  on property: part of
  some values from: ectoderm anlage
subclass of: Restriction
  on property: develops into
  some values from: anterior ectoderm
definition: Anlage that develops into the anterior ectoderm. It is found anterior to the dorsal, lateral and ventral regions of the ectoderm anlage and posterior to the anterior endoderm anlage at the cellular blastoderm stage, prior to gastrulation (Stathopoulos and Newcomb, 2020).
has OBO namespace: fly_anatomy.ontology
id: FBbt:01000119
in subset: cur

Axiom
annotated source: anterior ectoderm anlage
annotated property: definition
annotated target: Anlage that develops into the anterior ectoderm. It is found anterior to the dorsal, lateral and ventral regions of the ectoderm anlage and posterior to the anterior endoderm anlage at the cellular blastoderm stage, prior to gastrulation (Stathopoulos and Newcomb, 2020).
database_cross_reference: FlyBase:FBrf0244630

embryonic ventral trunk epidermis
type: Class
subclass of: ventral ectoderm derivative
subclass of: multicellular structure
subclass of: Restriction
  on property: part of
  some values from: embryonic ventral epidermis
subclass of: Restriction
  on property: develops from
  some values from: ventral trunk epidermis primordium
definition: The epidermis of the embryonic ventral trunk.
has OBO namespace: fly_anatomy.ontology
id: FBbt:01005747
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic ventral trunk epidermis
annotated property: definition
annotated target: The epidermis of the embryonic ventral trunk.
database_cross_reference: https://orcid.org/0000-0001-5948-3092

yellow ommatidium
type: Class
subclass of: ommatidium
definition: Ommatidial subtype with stochastic distribution throughout the retina making up about 70% of all non-dorsal margin ommatidia. This ommatidial subtype is specialized to detect longer wavelengths (far UV + green).
database_cross_reference: VFB:FBbt_02000001
has OBO namespace: fly_anatomy.ontology
id: FBbt:02000001
in subset: cur
comment: The yellow ommatidium expresses the far ultraviolet-specific opsin Rh4 (FBgn0003250) in photoreceptor R7 cells and the green-sensitive Rh6 (FBgn0019940) in photoreceptor R8 cells (Wernet and Desplan, 2004).

Axiom
annotated source: yellow ommatidium
annotated property: definition
annotated target: Ommatidial subtype with stochastic distribution throughout the retina making up about 70% of all non-dorsal margin ommatidia. This ommatidial subtype is specialized to detect longer wavelengths (far UV + green).
database_cross_reference: FlyBase:FBrf0180690

pale ommatidium
type: Class
subclass of: ommatidium
definition: Ommatidial subtype with stochastic distribution throughout the retina, making up about 30% of all non-dorsal margin ommatidia. This ommatidial subtype is specialized to detect shorter wavelengths (near UV + blue) than yellow ommatidia.
database_cross_reference: VFB:FBbt_02000002
has OBO namespace: fly_anatomy.ontology
id: FBbt:02000002
in subset: cur
comment: The pale ommatidium expresses the near ultraviolet-specific opsin Rh3 (FBgn0003249) in photoreceptor R7 cells and the blue-sensitive Rh5 (FBgn0014019) in photoreceptor R8 cells (Wernet and Desplan, 2004).

Axiom
annotated source: pale ommatidium
annotated property: definition
annotated target: Ommatidial subtype with stochastic distribution throughout the retina, making up about 30% of all non-dorsal margin ommatidia. This ommatidial subtype is specialized to detect shorter wavelengths (near UV + blue) than yellow ommatidia.
database_cross_reference: FlyBase:FBrf0180690

photoreceptor cell R8 of yellow ommatidium
type: Class
equivalent class: Class
  intersection of: photoreceptor cell R8
  intersection of: Restriction
    on property: part of
    some values from: yellow ommatidium
subclass of: photoreceptor cell R8
subclass of: Restriction
  on property: part of
  some values from: yellow ommatidium
subclass of: Restriction
  on property: expresses
  some values from: FBgn0019940
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: yellow optic column
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi4
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm20
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm5c
IAO_0000028: yR8
definition: Photoreceptor cell R8 that is part of a yellow ommatidium and expresses Rhodopsin 6 (Wernet and Desplan, 2004). It outputs to TM5c, mostly in layer M3 where it terminates, but also in M1-2 (Karuppudurai et al., 2014) and to Tm20, Mi1, Mi4 and some lamina monopolar neurons of the same column (Takemura et al., 2015). It also outputs onto photoreceptor cell R7 of the same column (Takemura et al., 2008; Takemura et al., 2015), mostly in M3 (Takemura et al., 2008).
database_cross_reference: VFB:FBbt_02000003
has exact synonym: yR8
has OBO namespace: fly_anatomy.ontology
id: FBbt:02000003
in subset: cur
comment: Connectivity with TM5c inferred from GRASP experiments (Karuppudurai et al., 2014). Connectivity with R7, Mi1, Mi4, Tm20 and lamina monopolar neurons based on EM data (Takemura et al., 2008; Takemura et al., 2015). Assertion in Gao et al. (2008) - FBrf0206213 that (non-DRA) R8 is synapsed to Tm9 is not supported by EM data in Takemura et al. (2015).

Axiom
annotated source: photoreceptor cell R8 of yellow ommatidium
annotated property: IAO_0000028
annotated target: yR8
database_cross_reference: FlyBase:FBrf0232800
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: photoreceptor cell R8 of yellow ommatidium
annotated property: definition
annotated target: Photoreceptor cell R8 that is part of a yellow ommatidium and expresses Rhodopsin 6 (Wernet and Desplan, 2004). It outputs to TM5c, mostly in layer M3 where it terminates, but also in M1-2 (Karuppudurai et al., 2014) and to Tm20, Mi1, Mi4 and some lamina monopolar neurons of the same column (Takemura et al., 2015). It also outputs onto photoreceptor cell R7 of the same column (Takemura et al., 2008; Takemura et al., 2015), mostly in M3 (Takemura et al., 2008).
database_cross_reference: FlyBase:FBrf0180690
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0230092

Axiom
annotated source: photoreceptor cell R8 of yellow ommatidium
annotated property: hasExactSynonym
annotated target: yR8
database_cross_reference: FlyBase:FBrf0232800
database_cross_reference: FlyBase:FBrf0252485
has synonym type: VFB SYMBOL

photoreceptor cell R8 of pale ommatidium
type: Class
equivalent class: Class
  intersection of: photoreceptor cell R8
  intersection of: Restriction
    on property: part of
    some values from: pale ommatidium
subclass of: photoreceptor cell R8
subclass of: Restriction
  on property: part of
  some values from: pale ommatidium
subclass of: Restriction
  on property: expresses
  some values from: FBgn0014019
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M1
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M2
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: pale optic column
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: lamina monopolar neuron
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi1
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: medulla intrinsic neuron Mi4
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm20
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm5c
IAO_0000028: pR8
definition: Photoreceptor cell R8 that is part of a pale ommatidium and expresses Rhodopsin 5 (Wernet and Desplan, 2004). It outputs to TM5c, mostly in layer M3 where it terminates, but also in M1-2 (Karuppudurai et al., 2014) and to Tm20, Mi1, Mi4 and some lamina monopolar neurons of the same column (Takemura et al., 2015). It also outputs onto photoreceptor cell R7 of the same column (Takemura et al., 2008; Takemura et al., 2015), mostly in M3 (Takemura et al., 2008).
database_cross_reference: VFB:FBbt_02000004
has exact synonym: pR8
has OBO namespace: fly_anatomy.ontology
id: FBbt:02000004
in subset: cur
comment: Connectivity with TM5c inferred from GRASP experiments (Karuppudurai et al., 2014). Connectivity with R7, Mi1, Mi4, Tm20 and lamina monopolar neurons based on EM data (Takemura et al., 2008; Takemura et al., 2015). Assertion in Gao et al. (2008) - FBrf0206213 that (non-DRA) R8 is synapsed to Tm9 is not supported by EM data in Takemura et al. (2015).

Axiom
annotated source: photoreceptor cell R8 of pale ommatidium
annotated property: IAO_0000028
annotated target: pR8
database_cross_reference: FlyBase:FBrf0232800
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: photoreceptor cell R8 of pale ommatidium
annotated property: definition
annotated target: Photoreceptor cell R8 that is part of a pale ommatidium and expresses Rhodopsin 5 (Wernet and Desplan, 2004). It outputs to TM5c, mostly in layer M3 where it terminates, but also in M1-2 (Karuppudurai et al., 2014) and to Tm20, Mi1, Mi4 and some lamina monopolar neurons of the same column (Takemura et al., 2015). It also outputs onto photoreceptor cell R7 of the same column (Takemura et al., 2008; Takemura et al., 2015), mostly in M3 (Takemura et al., 2008).
database_cross_reference: FlyBase:FBrf0180690
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0230092

Axiom
annotated source: photoreceptor cell R8 of pale ommatidium
annotated property: hasExactSynonym
annotated target: pR8
database_cross_reference: FlyBase:FBrf0232800
database_cross_reference: FlyBase:FBrf0252485
has synonym type: VFB SYMBOL

photoreceptor cell R7 of yellow ommatidium
type: Class
equivalent class: Class
  intersection of: photoreceptor cell R7
  intersection of: Restriction
    on property: part of
    some values from: yellow ommatidium
subclass of: photoreceptor cell R7
subclass of: Restriction
  on property: part of
  some values from: yellow ommatidium
subclass of: Restriction
  on property: expresses
  some values from: FBgn0003250
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: yellow optic column
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: distal medullary amacrine neuron Dm8a
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: transmedullary neuron Tm5a
IAO_0000028: yR7
definition: Photoreceptor cell R7 that is part of a yellow ommatidium and expresses Rhodopsin 4 (Wernet and Desplan, 2004). It outputs to transmedullary neuron Tm5a (Gao et al., 2008; Karuppudurai et al., 2014) and to Dm8 neurons in medulla layer M6 (Gao et al., 2008; Sancer et al., 2019). It receives synaptic input from photoreceptor cell R8 of the same column (Takemura et al., 2008; Takemura et al., 2015), mostly in M3 (Takemura et al., 2008).
database_cross_reference: VFB:FBbt_02000005
has exact synonym: yR7
has OBO namespace: fly_anatomy.ontology
id: FBbt:02000005
in subset: cur
comment: Connectivity with Tm5a inferred from EM reconstructions from a single medulla column (Gao et al., 2008) and selective arborization in yellow columns (Karuppudurai et al., 2014). Connectivity to Dm8 based on EM data (Gao et al., 2008). Connectivity with R8 based on EM data (Takemura et al., 2008; Takemura et al., 2015).

Axiom
annotated source: photoreceptor cell R7 of yellow ommatidium
annotated property: IAO_0000028
annotated target: yR7
database_cross_reference: FlyBase:FBrf0232800
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: photoreceptor cell R7 of yellow ommatidium
annotated property: definition
annotated target: Photoreceptor cell R7 that is part of a yellow ommatidium and expresses Rhodopsin 4 (Wernet and Desplan, 2004). It outputs to transmedullary neuron Tm5a (Gao et al., 2008; Karuppudurai et al., 2014) and to Dm8 neurons in medulla layer M6 (Gao et al., 2008; Sancer et al., 2019). It receives synaptic input from photoreceptor cell R8 of the same column (Takemura et al., 2008; Takemura et al., 2015), mostly in M3 (Takemura et al., 2008).
database_cross_reference: FlyBase:FBrf0180690
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0224070
database_cross_reference: FlyBase:FBrf0230092
database_cross_reference: FlyBase:FBrf0243430

Axiom
annotated source: photoreceptor cell R7 of yellow ommatidium
annotated property: hasExactSynonym
annotated target: yR7
database_cross_reference: FlyBase:FBrf0232800
database_cross_reference: FlyBase:FBrf0252485
has synonym type: VFB SYMBOL

photoreceptor cell R7 of pale ommatidium
type: Class
equivalent class: Class
  intersection of: photoreceptor cell R7
  intersection of: Restriction
    on property: part of
    some values from: pale ommatidium
subclass of: photoreceptor cell R7
subclass of: Restriction
  on property: part of
  some values from: pale ommatidium
subclass of: Restriction
  on property: expresses
  some values from: FBgn0003249
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M3
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: pale optic column
subclass of: Restriction
  on property: sends synaptic output to cell
  some values from: distal medullary amacrine neuron Dm8a
IAO_0000028: pR7
definition: Photoreceptor cell R7 that is part of a pale ommatidium and expresses Rhodopsin 3 (Wernet and Desplan, 2004). It outputs to Dm8 neurons in medulla layer M6 (Gao et al., 2008; Sancer et al., 2019). It receives synaptic input from photoreceptor cell R8 of the same column (Takemura et al., 2008; Takemura et al., 2015), mostly in M3 (Takemura et al., 2008).
database_cross_reference: VFB:FBbt_02000006
has exact synonym: pR7
has OBO namespace: fly_anatomy.ontology
id: FBbt:02000006
in subset: cur
comment: Connectivity to Dm8 based on EM data (Gao et al., 2008). Connectivity with R8 based on EM data (Takemura et al., 2008; Takemura et al., 2015).

Axiom
annotated source: photoreceptor cell R7 of pale ommatidium
annotated property: IAO_0000028
annotated target: pR7
database_cross_reference: FlyBase:FBrf0232800
database_cross_reference: FlyBase:FBrf0252485

Axiom
annotated source: photoreceptor cell R7 of pale ommatidium
annotated property: definition
annotated target: Photoreceptor cell R7 that is part of a pale ommatidium and expresses Rhodopsin 3 (Wernet and Desplan, 2004). It outputs to Dm8 neurons in medulla layer M6 (Gao et al., 2008; Sancer et al., 2019). It receives synaptic input from photoreceptor cell R8 of the same column (Takemura et al., 2008; Takemura et al., 2015), mostly in M3 (Takemura et al., 2008).
database_cross_reference: FlyBase:FBrf0180690
database_cross_reference: FlyBase:FBrf0205531
database_cross_reference: FlyBase:FBrf0206213
database_cross_reference: FlyBase:FBrf0230092
database_cross_reference: FlyBase:FBrf0243430

Axiom
annotated source: photoreceptor cell R7 of pale ommatidium
annotated property: hasExactSynonym
annotated target: pR7
database_cross_reference: FlyBase:FBrf0232800
database_cross_reference: FlyBase:FBrf0252485
has synonym type: VFB SYMBOL

anatomical entity
type: Class
equivalent class: Class
  intersection of: CARO_0000000
  intersection of: Restriction
    on property: part of
    some values from: Drosophila melanogaster
subclass of: CARO_0000000
subclass of: Restriction
  on property: part of
  some values from: Drosophila melanogaster
definition: Anatomical entity which is part_of Drosophila melanogaster.
has alternative id: FBbt_root:00000000
database_cross_reference: UBERON:0001062
has OBO namespace: fly_anatomy.ontology
has related synonym: Drosophila
id: FBbt:10000000
in subset: EmbDevSlim
in subset: cur
in subset: larval OF

Axiom
annotated source: anatomical entity
annotated property: definition
annotated target: Anatomical entity which is part_of Drosophila melanogaster.
database_cross_reference: https://orcid.org/0000-0001-9114-8737

embryonic primordium of adult eye
type: Class
subclass of: embryonic imaginal tissue
subclass of: primordium
subclass of: anterior ectoderm derivative
subclass of: Restriction
  on property: develops from
  some values from: visual primordium
subclass of: Restriction
  on property: develops into
  some values from: eye disc
definition: Primordium of the embryo that will give rise to the adult eye. It corresponds to the most anterior region that develops from the visual primordium.
has exact synonym: P1 Eye
has exact synonym: adult eye primordium
has OBO namespace: fly_anatomy.ontology
id: FBbt:10005249
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: embryonic primordium of adult eye
annotated property: definition
annotated target: Primordium of the embryo that will give rise to the adult eye. It corresponds to the most anterior region that develops from the visual primordium.
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0151275

Axiom
annotated source: embryonic primordium of adult eye
annotated property: hasExactSynonym
annotated target: P1 Eye
database_cross_reference: https://orcid.org/0000-0002-7073-9172

denticle field anlage
type: Class
subclass of: developing embryonic structure
subclass of: anlage
subclass of: ventral ectoderm derivative
subclass of: Restriction
  on property: part of
  some values from: late extended germ band embryo
subclass of: Restriction
  on property: develops from
  some values from: ventral epidermis primordium
subclass of: Restriction
  on property: develops into
  some values from: denticle field primordium
definition: A(n) anlage that develops into some denticle field primordium. It develops from some ventral epidermis primordium.
has OBO namespace: fly_anatomy.ontology
has related synonym: A DenBl
id: FBbt:10005326
in subset: EmbDevSlim
in subset: cur

Axiom
annotated source: denticle field anlage
annotated property: definition
annotated target: A(n) anlage that develops into some denticle field primordium. It develops from some ventral epidermis primordium.
database_cross_reference: FBC:Autogenerated

Axiom
annotated source: denticle field anlage
annotated property: hasRelatedSynonym
annotated target: A DenBl
database_cross_reference: https://orcid.org/0000-0002-7073-9172

adult transmedullary CB3851 neuron
type: Class
subclass of: transmedullary neuron
subclass of: Restriction
  on property: has soma location
  some values from: cell body rind of adult lateral medulla
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: medulla layer M6
subclass of: Restriction
  on property: receives synaptic input in region
  some values from: lobula layer 5
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: medulla layer M6
subclass of: Restriction
  on property: sends synaptic output to region
  some values from: lobula layer 5
IAO_0000028: CB3851
definition: Adult transmedullary neuron with its soma distal to the medulla (Nern et al., 2025). It is mainly postsynaptic, but also has presynapses, in around 5 columns of the medulla, with arbors mainly in M6, but also other layers from M3-M8 (Nern et al., 2025). It crosses the second optic chiasm and has mixed pre- and post-synapses in around 3 columns of lobula layer 5 (Nern et al., 2025). There are approximately 370-550 of these cells per hemisphere (Nern et al., 2025).
contributor: https://orcid.org/0000-0002-1373-1705
contributor: https://orcid.org/0000-0002-5633-1314
date: 2024-02-05T12:00:00Z
database_cross_reference: VFB:FBbt_20007266
has exact synonym: CB3851
has OBO namespace: fly_anatomy.ontology
id: FBbt:20007266
comment: Cell type from Schlegel et al. (2024), based on FlyWire v783 (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024), two of three (Tm29, Tm39, Tm40) proposed subtypes identified at light level by Nern et al. (2025).

Axiom
annotated source: adult transmedullary CB3851 neuron
annotated property: IAO_0000028
annotated target: CB3851
database_cross_reference: FlyBase:FBrf0260535

Axiom
annotated source: adult transmedullary CB3851 neuron
annotated property: definition
annotated target: Adult transmedullary neuron with its soma distal to the medulla (Nern et al., 2025). It is mainly postsynaptic, but also has presynapses, in around 5 columns of the medulla, with arbors mainly in M6, but also other layers from M3-M8 (Nern et al., 2025). It crosses the second optic chiasm and has mixed pre- and post-synapses in around 3 columns of lobula layer 5 (Nern et al., 2025). There are approximately 370-550 of these cells per hemisphere (Nern et al., 2025).
database_cross_reference: FlyBase:FBrf0260535
database_cross_reference: FlyBase:FBrf0260546
database_cross_reference: FlyBase:FBrf0262545

Axiom
annotated source: adult transmedullary CB3851 neuron
annotated property: hasExactSynonym
annotated target: CB3851
database_cross_reference: FlyBase:FBrf0260535
has synonym type: VFB SYMBOL

FlyBase CV
type: Class
definition: FlyBase miscellaneous controlled vocabulary term.
has OBO namespace: FlyBase miscellaneous CV
id: FBcv:0000000

descriptor
type: Class
subclass of: FlyBase CV
definition: Term that describes an allele, balancer, group or publication.
has OBO namespace: FlyBase miscellaneous CV
id: FBcv:0000013
in subset: do not annotate

Axiom
annotated source: descriptor
annotated property: definition
annotated target: Term that describes an allele, balancer, group or publication.
database_cross_reference: FBC:MMC

dataset descriptor
type: Class
subclass of: descriptor
definition: Term that describes a dataset.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: FlyBase miscellaneous CV
id: FBcv:0003021

Axiom
annotated source: dataset descriptor
annotated property: definition
annotated target: Term that describes a dataset.
database_cross_reference: FBC:GD

dataset entity type
type: Class
subclass of: dataset descriptor
definition: Term that specifies the dataset component type.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: dataset_entity_type
id: FBcv:0003022

Axiom
annotated source: dataset entity type
annotated property: definition
annotated target: Term that specifies the dataset component type.
database_cross_reference: FBC:GD

project
type: Class
subclass of: dataset entity type
definition: A set of biological data from a single study. Corresponds to the NCBI bioproject, GEO series or SRA study.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: dataset_entity_type
id: FBcv:0003023

Axiom
annotated source: project
annotated property: definition
annotated target: A set of biological data from a single study. Corresponds to the NCBI bioproject, GEO series or SRA study.
database_cross_reference: FBC:GD

biosample
type: Class
subclass of: dataset entity type
definition: Biological source material characterized by an experiment.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: dataset_entity_type
id: FBcv:0003024

Axiom
annotated source: biosample
annotated property: definition
annotated target: Biological source material characterized by an experiment.
database_cross_reference: FBC:GD

assay
type: Class
subclass of: dataset entity type
definition: Quantitative or qualitative assessment of biological source material to measure some attribute.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: dataset_entity_type
id: FBcv:0003025

Axiom
annotated source: assay
annotated property: definition
annotated target: Quantitative or qualitative assessment of biological source material to measure some attribute.
database_cross_reference: FBC:GD

dataset data type
type: Class
subclass of: dataset descriptor
definition: The data type content of a dataset.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: FlyBase miscellaneous CV
id: FBcv:0003028

Axiom
annotated source: dataset data type
annotated property: definition
annotated target: The data type content of a dataset.
database_cross_reference: FBC:GD

assay type
type: Class
subclass of: dataset data type
definition: The type of assay as characterized by its data content.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: assay_type
id: FBcv:0003050

Axiom
annotated source: assay type
annotated property: definition
annotated target: The type of assay as characterized by its data content.
database_cross_reference: FBC:GD

RNA-Seq
type: Class
subclass of: assay type
definition: A quantitative method for mapping transcribed regions, in which complementary DNA fragments are subjected to high-throughput sequencing.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
database_cross_reference: EFO:0008896
has OBO namespace: assay_type
id: FBcv:0003068

Axiom
annotated source: RNA-Seq
annotated property: definition
annotated target: A quantitative method for mapping transcribed regions, in which complementary DNA fragments are subjected to high-throughput sequencing.
database_cross_reference: PMID:18451266

result type
type: Class
subclass of: dataset data type
definition: The type of result as characterized by its data content.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: result_type
id: FBcv:0003082

Axiom
annotated source: result type
annotated property: definition
annotated target: The type of result as characterized by its data content.
database_cross_reference: FBC:GD

analysis
type: Class
subclass of: result type
definition: A result that is produced from the detailed examination of data to come to some conclusion.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: result_type
id: FBcv:0003108

Axiom
annotated source: analysis
annotated property: definition
annotated target: A result that is produced from the detailed examination of data to come to some conclusion.
database_cross_reference: FBC:GD

dataset attribute
type: Class
subclass of: dataset descriptor
definition: A descriptor that describes some aspect of a dataset.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: FlyBase miscellaneous CV
id: FBcv:0003121

Axiom
annotated source: dataset attribute
annotated property: definition
annotated target: A descriptor that describes some aspect of a dataset.
database_cross_reference: FBC:GD

assay attribute
type: Class
subclass of: dataset attribute
definition: Some characteristic of an assay pertaining to the methods involved in processing the biological source material or generating the raw output data of the assay.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: assay_attribute
id: FBcv:0003175

Axiom
annotated source: assay attribute
annotated property: definition
annotated target: Some characteristic of an assay pertaining to the methods involved in processing the biological source material or generating the raw output data of the assay.
database_cross_reference: FBC:GD

assay method
type: Class
subclass of: assay attribute
definition: A method used to characterize the biological molecules isolated from a biosample.
contributor: http://orcid.org/0000-0001-5948-3092
date: 2016-02-24T19:19:21Z
has OBO namespace: assay_attribute
id: FBcv:0003208

Axiom
annotated source: assay method
annotated property: definition
annotated target: A method used to characterize the biological molecules isolated from a biosample.
database_cross_reference: FBC:GD

single-cell RNA-Seq
type: Class
subclass of: RNA-Seq
definition: A method for quantifying the transcriptome of individual cells, in which transcripts isolated from single cells are subjected to high-throughput sequencing and mapping to a reference genome.
contributor: http://orcid.org/0000-0002-6095-8718
date: 2021-07-26T12:18:07Z
database_cross_reference: EFO:0008913
database_cross_reference: OBI:0002631
has exact synonym: scRNA-Seq
has exact synonym: single-cell RNA sequencing assay
has OBO namespace: assay_type
id: FBcv:0009000

Axiom
annotated source: single-cell RNA-Seq
annotated property: definition
annotated target: A method for quantifying the transcriptome of individual cells, in which transcripts isolated from single cells are subjected to high-throughput sequencing and mapping to a reference genome.
database_cross_reference: PMID:28821273

Axiom
annotated source: single-cell RNA-Seq
annotated property: hasExactSynonym
annotated target: scRNA-Seq
database_cross_reference: PMID:32405060

cell clustering analysis
type: Class
subclass of: analysis
definition: A result that groups individual cells into populations sharing a similar transcriptional profile.
contributor: http://orcid.org/0000-0002-6095-8718
date: 2021-07-26T12:21:05Z
has OBO namespace: result_type
id: FBcv:0009002

Axiom
annotated source: cell clustering analysis
annotated property: definition
annotated target: A result that groups individual cells into populations sharing a similar transcriptional profile.
database_cross_reference: PMID:28821273

transcriptional cell cluster
type: Class
subclass of: result type
definition: A result that represents a population of cells sharing a similar transcriptional profile.
contributor: http://orcid.org/0000-0002-6095-8718
date: 2021-07-26T12:22:16Z
has OBO namespace: result_type
id: FBcv:0009003

Axiom
annotated source: transcriptional cell cluster
annotated property: definition
annotated target: A result that represents a population of cells sharing a similar transcriptional profile.
database_cross_reference: PMID:28821273

single-cell library sequencing
type: Class
subclass of: assay method
definition: A method to prepare and sequence a library of cDNAs obtained from single cells.
contributor: http://orcid.org/0000-0002-6095-8718
date: 2021-07-26T13:40:26Z
has OBO namespace: assay_attribute
id: FBcv:0009005

Axiom
annotated source: single-cell library sequencing
annotated property: definition
annotated target: A method to prepare and sequence a library of cDNAs obtained from single cells.
database_cross_reference: FBC:DPG

10x sequencing
type: Class
subclass of: single-cell library sequencing
definition: A method that uses the Chromium platform from 10x Genomics to prepare and sequence a cDNA library.
contributor: http://orcid.org/0000-0002-6095-8718
date: 2021-07-26T13:45:06Z
has OBO namespace: assay_attribute
id: FBcv:0009008

Axiom
annotated source: 10x sequencing
annotated property: definition
annotated target: A method that uses the Chromium platform from 10x Genomics to prepare and sequence a cDNA library.
database_cross_reference: PMID:29126257

Drosophila life
type: Class
subclass of: BFO_0000003
definition: The life of an individual of the species Drosophila melanogaster, from fertilization to death.
has alternative id: FBdv_root:00000000
has exact synonym: Drosophila life cycle
has OBO namespace: FlyBase_development_CV
id: FBdv:00000000

Axiom
annotated source: Drosophila life
annotated property: definition
annotated target: The life of an individual of the species Drosophila melanogaster, from fertilization to death.
database_cross_reference: FBC:DOS

cleavage stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: fertilized egg stage
definition: Stage during which the nucleus of the fertilized egg performs 13 rapid divisions, prior to cellularization (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). The first seven divisions are synchronous (Campos-Ortega and Hartenstein, 1997). During the course of the subsequent three divisions, most of the nuclei approach the surface and then divide asynchronously a further three times, bringing the total number of cells to around 5000 (Campos-Ortega and Hartenstein, 1997). This corresponds to embryonic stages 1-4 (Hartenstein, 1993).
has OBO namespace: FlyBase_development_CV
id: FBdv:00000054
comment: Temporal ordering number - 25.

Axiom
annotated source: cleavage stage
annotated property: definition
annotated target: Stage during which the nucleus of the fertilized egg performs 13 rapid divisions, prior to cellularization (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997). The first seven divisions are synchronous (Campos-Ortega and Hartenstein, 1997). During the course of the subsequent three divisions, most of the nuclei approach the surface and then divide asynchronously a further three times, bringing the total number of cells to around 5000 (Campos-Ortega and Hartenstein, 1997). This corresponds to embryonic stages 1-4 (Hartenstein, 1993).
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570

late extended germ band stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 10
subclass of: Restriction
  on property: immediately preceded by
  some values from: early extended germ band stage
definition: A collective term for stages 11 and 12.
has OBO namespace: FlyBase_development_CV
id: FBdv:00004450
comment: Temporal ordering number - 300.

Axiom
annotated source: late extended germ band stage
annotated property: definition
annotated target: A collective term for stages 11 and 12.
database_cross_reference: FBC:DOS

oogenesis
type: Class
subclass of: developmental process
definition: The complete process of formation and maturation of an ovum or female gemate from a primordial female germ cell.
database_cross_reference: GO:0048477
has exact synonym: oogenesis stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00004886
comment: Temporal ordering number - 10000.

Axiom
annotated source: oogenesis
annotated property: definition
annotated target: The complete process of formation and maturation of an ovum or female gemate from a primordial female germ cell.
database_cross_reference: GO:0048477

developmental stage
type: Class
subclass of: BFO_0000003
definition: A temporal subdivision of a developmental process.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2009-10-01T05:56:56Z
has alternative id: FBdv:00007010
has OBO namespace: FlyBase_development_CV
id: FBdv:00005259

Axiom
annotated source: developmental stage
annotated property: definition
annotated target: A temporal subdivision of a developmental process.
database_cross_reference: FBC:DOS

oogenesis stage S1
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
definition: Earliest stage of ovarian cyst development - lasts while the 16 cell cyst is within the germarium (region 3).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005261
comment: Temporal ordering number - 10010.

Axiom
annotated source: oogenesis stage S1
annotated property: definition
annotated target: Earliest stage of ovarian cyst development - lasts while the 16 cell cyst is within the germarium (region 3).
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S2
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S1
definition: Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005262
comment: Temporal ordering number - 10020.

Axiom
annotated source: oogenesis stage S2
annotated property: definition
annotated target: Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S3
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S2
definition: Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005263
comment: Temporal ordering number - 10030.

Axiom
annotated source: oogenesis stage S3
annotated property: definition
annotated target: Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S4
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S3
definition: Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005264
comment: Temporal ordering number - 10040.

Axiom
annotated source: oogenesis stage S4
annotated property: definition
annotated target: Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S5
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S4
definition: Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005265
comment: Temporal ordering number - 10050.

Axiom
annotated source: oogenesis stage S5
annotated property: definition
annotated target: Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S6
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S5
definition: Oogenesis stage during which follicle cell division ceases.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005266
comment: Temporal ordering number - 10060.

Axiom
annotated source: oogenesis stage S6
annotated property: definition
annotated target: Oogenesis stage during which follicle cell division ceases.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S7
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S6
definition: Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005267
comment: Temporal ordering number - 10070.

Axiom
annotated source: oogenesis stage S7
annotated property: definition
annotated target: Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S8
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S7
definition: Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005268
comment: Temporal ordering number - 10080.

Axiom
annotated source: oogenesis stage S8
annotated property: definition
annotated target: Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S9
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S8
definition: Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005269
comment: Temporal ordering number - 10090.

Axiom
annotated source: oogenesis stage S9
annotated property: definition
annotated target: Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S10
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S9
definition: Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005270
comment: Temporal ordering number - 10100.

Axiom
annotated source: oogenesis stage S10
annotated property: definition
annotated target: Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S10A
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S10
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S9
definition: Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005271
comment: Temporal ordering number - 10110.

Axiom
annotated source: oogenesis stage S10A
annotated property: definition
annotated target: Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074

oogenesis stage S10B
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S10
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S10A
definition: Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005272
comment: Temporal ordering number - 10120.

Axiom
annotated source: oogenesis stage S10B
annotated property: definition
annotated target: Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S11
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S10
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S10B
definition: Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005273
comment: Temporal ordering number - 10130.

Axiom
annotated source: oogenesis stage S11
annotated property: definition
annotated target: Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0043885
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S12
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S11
definition: Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005274
comment: Temporal ordering number - 10160.

Axiom
annotated source: oogenesis stage S12
annotated property: definition
annotated target: Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0043885
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S12A
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S12
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S11
definition: Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005275
comment: Temporal ordering number - 10170.

Axiom
annotated source: oogenesis stage S12A
annotated property: definition
annotated target: Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.
database_cross_reference: FlyBase:FBrf0043885

oogenesis stage S12B
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S12
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S12A
definition: Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005276
comment: Temporal ordering number - 10180.

Axiom
annotated source: oogenesis stage S12B
annotated property: definition
annotated target: Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.
database_cross_reference: FlyBase:FBrf0043885

oogenesis stage S12C
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S12
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S12B
definition: Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005277
comment: Temporal ordering number - 10190.

Axiom
annotated source: oogenesis stage S12C
annotated property: definition
annotated target: Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.
database_cross_reference: FlyBase:FBrf0021038

oogenesis stage S13
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S12
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S12C
definition: Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005278
comment: Temporal ordering number - 10200.

Axiom
annotated source: oogenesis stage S13
annotated property: definition
annotated target: Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0029744
database_cross_reference: FlyBase:FBrf0034074
database_cross_reference: FlyBase:FBrf0064777

oogenesis stage S13A
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S13
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S12C
definition: Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005279
comment: Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure.

Axiom
annotated source: oogenesis stage S13A
annotated property: definition
annotated target: Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.
database_cross_reference: FlyBase:FBrf0029744

oogenesis stage S13B
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S13
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S13A
definition: Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005280
comment: Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure.

Axiom
annotated source: oogenesis stage S13B
annotated property: definition
annotated target: Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.
database_cross_reference: FlyBase:FBrf0029744

oogenesis stage S13C
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S13
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S13B
definition: Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005281
comment: Temporal ordering number - 10230.

Axiom
annotated source: oogenesis stage S13C
annotated property: definition
annotated target: Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.
database_cross_reference: FlyBase:FBrf0029744

oogenesis stage S13D
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S13
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S13C
definition: Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005282
comment: Temporal ordering number - 10240.

Axiom
annotated source: oogenesis stage S13D
annotated property: definition
annotated target: Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.
database_cross_reference: FlyBase:FBrf0029744

oogenesis stage S14
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S13
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S13D
definition: The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005283
comment: Temporal ordering number - 10260.

Axiom
annotated source: oogenesis stage S14
annotated property: definition
annotated target: The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.
database_cross_reference: FlyBase:FBrf0043885

oogenesis stage S14A
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S14
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S13D
definition: Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005284
comment: Temporal ordering number - 10270.

Axiom
annotated source: oogenesis stage S14A
annotated property: definition
annotated target: Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0043885

oogenesis stage S14B
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: oogenesis stage S14
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S14A
definition: Secretion of the exochorion begins and ends.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005285
comment: Temporal ordering number - 10280.

Axiom
annotated source: oogenesis stage S14B
annotated property: definition
annotated target: Secretion of the exochorion begins and ends.
database_cross_reference: FlyBase:FBrf0021038
database_cross_reference: FlyBase:FBrf0043885

egg stage
type: Class
subclass of: developmental stage
definition: The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005286
comment: Temporal ordering number - 10290.

Axiom
annotated source: egg stage
annotated property: definition
annotated target: The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.
database_cross_reference: FlyBase:FBrf0064779

unfertilized egg stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: egg stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S14
subclass of: Restriction
  on property: immediately preceded by
  some values from: oogenesis stage S14B
definition: Developmental stage that starts with ovulation, at the end of oogenesis, until the egg is fertilized by a sperm.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005287
comment: Temporal ordering number - 10300.

Axiom
annotated source: unfertilized egg stage
annotated property: definition
annotated target: Developmental stage that starts with ovulation, at the end of oogenesis, until the egg is fertilized by a sperm.
database_cross_reference: FlyBase:FBrf0158848

fertilized egg stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: egg stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: unfertilized egg stage
definition: Developmental stage that starts with sperm entry until the first mitotic division of the zygote.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005288
comment: Temporal ordering number - 10.

Axiom
annotated source: fertilized egg stage
annotated property: definition
annotated target: Developmental stage that starts with sperm entry until the first mitotic division of the zygote.
database_cross_reference: FlyBase:FBrf0229233

embryonic stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: unfertilized egg stage
subclass of: Restriction
  on property: immediately precedes
  some values from: larval stage
subclass of: Restriction
  on property: immediately precedes
  some values from: first instar larval stage
definition: Life stage that begins with a fertilized egg, and finishes with hatching at the end of embryonic stage 17 (Campos-Ortega and Hartenstein, 1997).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005289
comment: Temporal ordering number - 20.

Axiom
annotated source: embryonic stage
annotated property: definition
annotated target: Life stage that begins with a fertilized egg, and finishes with hatching at the end of embryonic stage 17 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0089570

pre-blastoderm stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: cleavage stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: fertilized egg stage
definition: Stage prior to the formation of the syncitial blastoderm, including the first 9 cell divisions and the migration of nuclei to the periphery (cortex) of the embryo (Foe and Alberts, 1983; Jaeger et al., 2012). This lasts from fertilization to embryonic stage 3 (Campos-Ortega and Hartenstein, 1997).
has exact synonym: pre-blastoderm
has OBO namespace: FlyBase_development_CV
id: FBdv:00005290
comment: Temporal ordering number - 30.

Axiom
annotated source: pre-blastoderm stage
annotated property: definition
annotated target: Stage prior to the formation of the syncitial blastoderm, including the first 9 cell divisions and the migration of nuclei to the periphery (cortex) of the embryo (Foe and Alberts, 1983; Jaeger et al., 2012). This lasts from fertilization to embryonic stage 3 (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0039741
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0220623

embryonic stage 1
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pre-blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: fertilized egg stage
definition: The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005291
comment: Temporal ordering number - 40.

Axiom
annotated source: embryonic stage 1
annotated property: definition
annotated target: The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0064779
database_cross_reference: FlyBase:FBrf0089570

embryonic cycle 1
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 1
subclass of: Restriction
  on property: immediately preceded by
  some values from: fertilized egg stage
definition: The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005292
comment: Temporal ordering number - 50.

Axiom
annotated source: embryonic cycle 1
annotated property: definition
annotated target: The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

embryonic stage 2
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pre-blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 1
definition: Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005293
comment: Temporal ordering number - 70.

Axiom
annotated source: embryonic stage 2
annotated property: definition
annotated target: Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).
database_cross_reference: FlyBase:FBrf0089570

embryonic cycle 2
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 1
definition: The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005294
comment: Temporal ordering number - 60.

Axiom
annotated source: embryonic cycle 2
annotated property: definition
annotated target: The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

embryonic cycle 3
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 1
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 2
definition: The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005295
comment: Temporal ordering number - 80.

Axiom
annotated source: embryonic cycle 3
annotated property: definition
annotated target: The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

embryonic cycle 4
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 3
definition: The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005296
comment: Temporal ordering number - 90.

Axiom
annotated source: embryonic cycle 4
annotated property: definition
annotated target: The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

embryonic cycle 5
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 4
definition: The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005297
comment: Temporal ordering number - 100.

Axiom
annotated source: embryonic cycle 5
annotated property: definition
annotated target: The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

embryonic cycle 6
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 5
definition: The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005298
comment: Temporal ordering number - 110.

Axiom
annotated source: embryonic cycle 6
annotated property: definition
annotated target: The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

embryonic cycle 7
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 6
definition: The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005299
comment: Temporal ordering number - 120.

Axiom
annotated source: embryonic cycle 7
annotated property: definition
annotated target: The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

embryonic cycle 8
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 7
definition: The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005300
comment: Temporal ordering number - 130.

Axiom
annotated source: embryonic cycle 8
annotated property: definition
annotated target: The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

embryonic stage 3
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pre-blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 8
definition: Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005301
comment: Temporal ordering number - 140.

Axiom
annotated source: embryonic stage 3
annotated property: definition
annotated target: Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic cycle 9
type: Class
subclass of: embryonic cycle
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 3
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 2
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 8
definition: The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005302
comment: Temporal ordering number - 150.

Axiom
annotated source: embryonic cycle 9
annotated property: definition
annotated target: The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.
database_cross_reference: FlyBase:FBrf0049535

blastoderm stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pre-blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 3
definition: Stage during which most of the nuclei are arranged as a monolayer at the cortex (periphery) of the embryo (Foe and Alberts, 1983; Jaeger et al., 2012). It begins shortly after completion of the ninth cleavage division and lasts until the onset of gastrulation, including cleavage cycles 10-14A (Foe and Alberts, 1983; Jaeger et al., 2012). This corresponds to embryonic stages 4 (syncitial blastoderm stage) and 5 (cellular blastoderm stage) (Campos-Ortega and Hartenstein, 1997).
has exact synonym: blastoderm
has OBO namespace: FlyBase_development_CV
id: FBdv:00005304
comment: Temporal ordering number - 160.

Axiom
annotated source: blastoderm stage
annotated property: definition
annotated target: Stage during which most of the nuclei are arranged as a monolayer at the cortex (periphery) of the embryo (Foe and Alberts, 1983; Jaeger et al., 2012). It begins shortly after completion of the ninth cleavage division and lasts until the onset of gastrulation, including cleavage cycles 10-14A (Foe and Alberts, 1983; Jaeger et al., 2012). This corresponds to embryonic stages 4 (syncitial blastoderm stage) and 5 (cellular blastoderm stage) (Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0039741
database_cross_reference: FlyBase:FBrf0089570
database_cross_reference: FlyBase:FBrf0220623

embryonic stage 4
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pre-blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 3
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic cycle 9
definition: Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).
has exact synonym: syncytial blastoderm stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005306
comment: Temporal ordering number - 170.

Axiom
annotated source: embryonic stage 4
annotated property: definition
annotated target: Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: embryonic stage 4
annotated property: hasExactSynonym
annotated target: syncytial blastoderm stage
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 5
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: cleavage stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 4
definition: Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).
has exact synonym: cellular blastoderm stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005311
comment: Temporal ordering number - 210.

Axiom
annotated source: embryonic stage 5
annotated property: definition
annotated target: Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

Axiom
annotated source: embryonic stage 5
annotated property: hasExactSynonym
annotated target: cellular blastoderm stage
database_cross_reference: FlyBase:FBrf0089570

gastrula stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 5
definition: Stage during which gastrulation occurs. During this stage, cells from the polar caps and the mid-ventral part of the blastoderm invaginate and ultimately generate the germ layers (Hartenstein, 1993). This encompasses embryonic stages 6-8 (Hartenstein, 1993).
has exact synonym: gastrula
has exact synonym: gastrulation stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005317
comment: Temporal ordering number - 220.

Axiom
annotated source: gastrula stage
annotated property: definition
annotated target: Stage during which gastrulation occurs. During this stage, cells from the polar caps and the mid-ventral part of the blastoderm invaginate and ultimately generate the germ layers (Hartenstein, 1993). This encompasses embryonic stages 6-8 (Hartenstein, 1993).
database_cross_reference: FlyBase:FBrf0064803

embryonic stage 6
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: gastrula stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: blastoderm stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 5
definition: Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005318
comment: Temporal ordering number - 230.

Axiom
annotated source: embryonic stage 6
annotated property: definition
annotated target: Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 7
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: gastrula stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 6
definition: Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005319
comment: Temporal ordering number - 240.

Axiom
annotated source: embryonic stage 7
annotated property: definition
annotated target: Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

extended germ band stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: gastrula stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 8
definition: Stages during which the germ band is extended - 9-12.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005321
comment: Temporal ordering number - 260.

Axiom
annotated source: extended germ band stage
annotated property: definition
annotated target: Stages during which the germ band is extended - 9-12.
database_cross_reference: FBC:DOS
database_cross_reference: FlyBase:FBrf0229323

embryonic stage 8
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: gastrula stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 7
definition: Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).
has exact synonym: rapidly extending germ band stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005322
comment: Temporal ordering number - 250.

Axiom
annotated source: embryonic stage 8
annotated property: definition
annotated target: Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 9
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: early extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: gastrula stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 8
definition: Stage 9 begins when mesodermal segmentation becomes (transiently) visible, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005323
comment: Temporal ordering number - 280.

Axiom
annotated source: embryonic stage 9
annotated property: definition
annotated target: Stage 9 begins when mesodermal segmentation becomes (transiently) visible, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 10
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: early extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 9
definition: Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005324
comment: Temporal ordering number - 290.

Axiom
annotated source: embryonic stage 10
annotated property: definition
annotated target: Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 11
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: late extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 10
subclass of: Restriction
  on property: immediately preceded by
  some values from: early extended germ band stage
definition: Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005325
comment: Temporal ordering number - 310.

Axiom
annotated source: embryonic stage 11
annotated property: definition
annotated target: Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 12
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: late extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 11
definition: Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).
has exact synonym: retracting germ band stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005327
comment: Temporal ordering number - 320.

Axiom
annotated source: embryonic stage 12
annotated property: definition
annotated target: Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 13
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: dorsal closure stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: late extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 12
definition: Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).
has exact synonym: contracted germ band stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005328
comment: Temporal ordering number - 340.

Axiom
annotated source: embryonic stage 13
annotated property: definition
annotated target: Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 14
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: dorsal closure stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 13
definition: Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).
has exact synonym: head involution stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005330
comment: Temporal ordering number - 350.

Axiom
annotated source: embryonic stage 14
annotated property: definition
annotated target: Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

dorsal closure stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: late extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 12
definition: Stage following germ band retraction, during which dorsal closure happens (Hartenstein, 1993). Dorsal closure occurs by extension of the dorsal epidermal primordium on either side, leading to fusion at the dorsal midline (Campos-Ortega and Hartenstein, 1997). This corresponds to embryonic stages 13-15 (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005331
comment: Temporal ordering number - 330.

Axiom
annotated source: dorsal closure stage
annotated property: definition
annotated target: Stage following germ band retraction, during which dorsal closure happens (Hartenstein, 1993). Dorsal closure occurs by extension of the dorsal epidermal primordium on either side, leading to fusion at the dorsal midline (Campos-Ortega and Hartenstein, 1997). This corresponds to embryonic stages 13-15 (Hartenstein, 1993; Campos-Ortega and Hartenstein, 1997).
database_cross_reference: FlyBase:FBrf0064803
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 15
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: dorsal closure stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 14
definition: Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005332
comment: Temporal ordering number - 360.

Axiom
annotated source: embryonic stage 15
annotated property: definition
annotated target: Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

late embryonic stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: dorsal closure stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 15
definition: Embryonic stages 16-17.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005333
comment: Temporal ordering number - 370.

Axiom
annotated source: late embryonic stage
annotated property: definition
annotated target: Embryonic stages 16-17.
database_cross_reference: FBC:DOS

embryonic stage 16
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: late embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: dorsal closure stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 15
definition: Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005334
comment: Temporal ordering number - 380.

Axiom
annotated source: embryonic stage 16
annotated property: definition
annotated target: Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).
database_cross_reference: FlyBase:FBrf0089570

embryonic stage 17
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: late embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 16
definition: Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005335
comment: Temporal ordering number - 390.

Axiom
annotated source: embryonic stage 17
annotated property: definition
annotated target: Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).
database_cross_reference: FlyBase:FBrf0089570

larval stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 17
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 17(iv)
subclass of: Restriction
  on property: immediately precedes
  some values from: prepupal stage
subclass of: Restriction
  on property: immediately precedes
  some values from: P-stage
definition: The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005336
comment: Temporal ordering number - 400.

Axiom
annotated source: larval stage
annotated property: definition
annotated target: The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.
database_cross_reference: FBC:DOS

first instar larval stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: substage of
  some values from: larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: late embryonic stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 17
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 17(iv)
subclass of: Restriction
  on property: immediately precedes
  some values from: second instar larval stage
definition: The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).
database_cross_reference: UBERON:8000000
has exact synonym: L1
has exact synonym: first instar larva
has OBO namespace: FlyBase_development_CV
id: FBdv:00005337
comment: Temporal ordering number - 410.

Axiom
annotated source: first instar larval stage
annotated property: definition
annotated target: The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).
database_cross_reference: FlyBase:FBrf0007733

second instar larval stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: substage of
  some values from: larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: first instar larval stage
subclass of: Restriction
  on property: immediately precedes
  some values from: third instar larval stage
definition: The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).
database_cross_reference: UBERON:8000001
has exact synonym: L2
has exact synonym: second instar larva
has OBO namespace: FlyBase_development_CV
id: FBdv:00005338
comment: Temporal ordering number - 420.

Axiom
annotated source: second instar larval stage
annotated property: definition
annotated target: The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).
database_cross_reference: FlyBase:FBrf0007733

third instar larval stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: substage of
  some values from: larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: second instar larval stage
subclass of: Restriction
  on property: immediately precedes
  some values from: prepupal stage
subclass of: Restriction
  on property: immediately precedes
  some values from: P-stage
definition: The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).
database_cross_reference: UBERON:8000002
has exact synonym: L3
has OBO namespace: FlyBase_development_CV
has related synonym: third instar larva
id: FBdv:00005339
comment: Temporal ordering number - 430.

Axiom
annotated source: third instar larval stage
annotated property: definition
annotated target: The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).
database_cross_reference: FlyBase:FBrf0007733

early third instar larval stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: second instar larval stage
definition: Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).
contributor: http://orcid.org/0000-0002-7073-9172
date: 2008-11-13T11:51:56Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00005340
comment: Temporal ordering number - 440.

Axiom
annotated source: early third instar larval stage
annotated property: definition
annotated target: Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).
database_cross_reference: FlyBase:FBrf0049147

wandering third instar larval stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: late third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: early third instar larval stage
definition: Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2008-11-13T11:55:46Z
has broad synonym: late third instar
has broad synonym: post-feeding larva
has OBO namespace: FlyBase_development_CV
id: FBdv:00005341
comment: Temporal ordering number - 460.

Axiom
annotated source: wandering third instar larval stage
annotated property: definition
annotated target: Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.
database_cross_reference: FlyBase:FBrf0049147

prepupal stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: substage of
  some values from: P-stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar larval stage L2
subclass of: Restriction
  on property: immediately preceded by
  some values from: late third instar larval stage
subclass of: Restriction
  on property: immediately precedes
  some values from: pupal stage
definition: The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005342
comment: Temporal ordering number - 500.

Axiom
annotated source: prepupal stage
annotated property: definition
annotated target: The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

prepupal stage P1
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: prepupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar larval stage L2
subclass of: Restriction
  on property: immediately preceded by
  some values from: late third instar larval stage
definition: Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).
has exact synonym: pupal stage P1
has exact synonym: puparium formation
has exact synonym: white puparium stage
has narrow synonym: pupal stage P0
has narrow synonym: white prepupa
has OBO namespace: FlyBase_development_CV
id: FBdv:00005343
comment: Temporal ordering number - 510.

Axiom
annotated source: prepupal stage P1
annotated property: definition
annotated target: Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: prepupal stage P1
annotated property: hasExactSynonym
annotated target: puparium formation
database_cross_reference: FlyBase:FBrf0036849

Axiom
annotated source: prepupal stage P1
annotated property: hasExactSynonym
annotated target: white puparium stage
database_cross_reference: FlyBase:FBrf0036849

Axiom
annotated source: prepupal stage P1
annotated property: hasNarrowSynonym
annotated target: pupal stage P0
database_cross_reference: FlyBase:FBrf0036849

Axiom
annotated source: prepupal stage P1
annotated property: hasNarrowSynonym
annotated target: white prepupa
database_cross_reference: FlyBase:FBrf0036849

prepupal stage P2
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: prepupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P1
definition: Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).
has exact synonym: brown puparium stage
has exact synonym: pupal stage P2
has OBO namespace: FlyBase_development_CV
id: FBdv:00005344
comment: Temporal ordering number - 520.

Axiom
annotated source: prepupal stage P2
annotated property: definition
annotated target: Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: prepupal stage P2
annotated property: hasExactSynonym
annotated target: brown puparium stage
database_cross_reference: FlyBase:FBrf0036849

prepupal stage P3
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: prepupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P2
definition: Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).
has exact synonym: bubble prepupa stage
has exact synonym: pupal stage P3
has OBO namespace: FlyBase_development_CV
id: FBdv:00005345
comment: Temporal ordering number - 530.

Axiom
annotated source: prepupal stage P3
annotated property: definition
annotated target: Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: prepupal stage P3
annotated property: hasExactSynonym
annotated target: bubble prepupa stage
database_cross_reference: FlyBase:FBrf0036849

prepupal stage P4
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: prepupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P3
definition: Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).
has exact synonym: cryptocephalic pupa
has exact synonym: pupal stage P4
has OBO namespace: FlyBase_development_CV
id: FBdv:00005346
comment: Temporal ordering number - 540.

Axiom
annotated source: prepupal stage P4
annotated property: definition
annotated target: Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: prepupal stage P4
annotated property: hasExactSynonym
annotated target: cryptocephalic pupa
database_cross_reference: FlyBase:FBrf0036849

prepupal stage P4(i)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: prepupal stage P4
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P3
definition: Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).
has exact synonym: buoyant stage
has exact synonym: pupal stage P4(i)
has OBO namespace: FlyBase_development_CV
id: FBdv:00005347
comment: Temporal ordering number - 550.

Axiom
annotated source: prepupal stage P4(i)
annotated property: definition
annotated target: Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: prepupal stage P4(i)
annotated property: hasExactSynonym
annotated target: buoyant stage
database_cross_reference: FlyBase:FBrf0036849

prepupal stage P4(ii)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: prepupal stage P4
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P4(i)
definition: Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).
has exact synonym: moving bubble stage
has exact synonym: pupal stage P4(ii)
has OBO namespace: FlyBase_development_CV
id: FBdv:00005348
comment: Temporal ordering number - 560.

Axiom
annotated source: prepupal stage P4(ii)
annotated property: definition
annotated target: Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: prepupal stage P4(ii)
annotated property: hasExactSynonym
annotated target: moving bubble stage
database_cross_reference: FlyBase:FBrf0036849

pupal stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: substage of
  some values from: P-stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage
subclass of: Restriction
  on property: immediately precedes
  some values from: pharate adult stage
definition: The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).
has exact synonym: phanerocephalic pupa
has OBO namespace: FlyBase_development_CV
id: FBdv:00005349
comment: Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage.

Axiom
annotated source: pupal stage
annotated property: definition
annotated target: The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pupal stage
annotated property: hasExactSynonym
annotated target: phanerocephalic pupa
database_cross_reference: FlyBase:FBrf0036849

pupal stage P5
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P4
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P4(ii)
definition: Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).
has OBO namespace: FlyBase_development_CV
id: FBdv:00005350
comment: Temporal ordering number - 580.

Axiom
annotated source: pupal stage P5
annotated property: definition
annotated target: Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

pupal stage P5(i)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pupal stage P5
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P4
subclass of: Restriction
  on property: immediately preceded by
  some values from: prepupal stage P4(ii)
definition: Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).
has exact synonym: Malpighian tubules migrating
has OBO namespace: FlyBase_development_CV
id: FBdv:00005351
comment: Temporal ordering number - 590.

Axiom
annotated source: pupal stage P5(i)
annotated property: definition
annotated target: Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pupal stage P5(i)
annotated property: hasExactSynonym
annotated target: Malpighian tubules migrating
database_cross_reference: FlyBase:FBrf0036849

pupal stage P5(ii)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pupal stage P5
subclass of: Restriction
  on property: immediately preceded by
  some values from: pupal stage P5(i)
definition: Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).
has exact synonym: white Malpighian tubules stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005352
comment: Temporal ordering number - 600.

Axiom
annotated source: pupal stage P5(ii)
annotated property: definition
annotated target: Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pupal stage P5(ii)
annotated property: hasExactSynonym
annotated target: white Malpighian tubules stage
database_cross_reference: FlyBase:FBrf0036849

pupal stage P6
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pupal stage P5
subclass of: Restriction
  on property: immediately preceded by
  some values from: pupal stage P5(ii)
definition: Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).
has exact synonym: green Malpighian tubules stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005353
comment: Temporal ordering number - 610.

Axiom
annotated source: pupal stage P6
annotated property: definition
annotated target: Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pupal stage P6
annotated property: hasExactSynonym
annotated target: green Malpighian tubules stage
database_cross_reference: FlyBase:FBrf0036849

pupal stage P7
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pupal stage P6
definition: The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).
has exact synonym: yellow body stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005354
comment: Temporal ordering number - 620.

Axiom
annotated source: pupal stage P7
annotated property: definition
annotated target: The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pupal stage P7
annotated property: hasExactSynonym
annotated target: yellow body stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P8
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pupal stage P7
definition: Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).
has exact synonym: pupal stage P8
has exact synonym: yellow-eyed stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005355
comment: Temporal ordering number - 630.

Axiom
annotated source: pharate adult stage P8
annotated property: definition
annotated target: Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P8
annotated property: hasExactSynonym
annotated target: yellow-eyed stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P9
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P8
definition: Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).
has exact synonym: amber-eyed stage
has exact synonym: pupal stage P9
has OBO namespace: FlyBase_development_CV
id: FBdv:00005356
comment: Temporal ordering number - 640.

Axiom
annotated source: pharate adult stage P9
annotated property: definition
annotated target: Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P9
annotated property: hasExactSynonym
annotated target: amber-eyed stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P10
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P9
definition: Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).
has exact synonym: pupal stage P10
has exact synonym: red-eye bald stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005357
comment: Temporal ordering number - 650.

Axiom
annotated source: pharate adult stage P10
annotated property: definition
annotated target: Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P10
annotated property: hasExactSynonym
annotated target: red-eye bald stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P11
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P10
definition: Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).
has exact synonym: pupal stage P11
has OBO namespace: FlyBase_development_CV
id: FBdv:00005358
comment: Temporal ordering number - 660.

Axiom
annotated source: pharate adult stage P11
annotated property: definition
annotated target: Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

pharate adult stage P11(i)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage P11
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P10
definition: Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).
has exact synonym: head bristles stage
has exact synonym: pupal stage P11(i)
has OBO namespace: FlyBase_development_CV
id: FBdv:00005359
comment: Temporal ordering number - 670.

Axiom
annotated source: pharate adult stage P11(i)
annotated property: definition
annotated target: Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P11(i)
annotated property: hasExactSynonym
annotated target: head bristles stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P11(ii)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage P11
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P11(i)
definition: Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).
has exact synonym: pupal stage P11(ii)
has exact synonym: thoracic bristles stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005360
comment: Temporal ordering number - 680.

Axiom
annotated source: pharate adult stage P11(ii)
annotated property: definition
annotated target: Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P11(ii)
annotated property: hasExactSynonym
annotated target: thoracic bristles stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P12
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P11
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P11(ii)
definition: Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).
has exact synonym: pupal stage P12
has OBO namespace: FlyBase_development_CV
id: FBdv:00005361
comment: Temporal ordering number - 690.

Axiom
annotated source: pharate adult stage P12
annotated property: definition
annotated target: Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

pharate adult stage P12(i)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage P12
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P11
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P11(ii)
definition: Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).
has exact synonym: pupal stage P12(i)
has exact synonym: wing tips grey stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005362
comment: Temporal ordering number - 700.

Axiom
annotated source: pharate adult stage P12(i)
annotated property: definition
annotated target: Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P12(i)
annotated property: hasExactSynonym
annotated target: wing tips grey stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P12(ii)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage P12
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P12(i)
definition: Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).
has exact synonym: pupal stage P12(ii)
has exact synonym: wings grey stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005363
comment: Temporal ordering number - 710.

Axiom
annotated source: pharate adult stage P12(ii)
annotated property: definition
annotated target: Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P12(ii)
annotated property: hasExactSynonym
annotated target: wings grey stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P13
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P12
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P12(ii)
definition: Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).
has exact synonym: pupal stage P13
has exact synonym: wings black stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00005364
comment: Temporal ordering number - 720.

Axiom
annotated source: pharate adult stage P13
annotated property: definition
annotated target: Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P13
annotated property: hasExactSynonym
annotated target: wings black stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P14
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P13
definition: The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).
has exact synonym: mature bristles stage
has exact synonym: pupal stage P14
has OBO namespace: FlyBase_development_CV
id: FBdv:00005365
comment: Temporal ordering number - 730.

Axiom
annotated source: pharate adult stage P14
annotated property: definition
annotated target: The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P14
annotated property: hasExactSynonym
annotated target: mature bristles stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P15
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P14
definition: Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).
has exact synonym: pupal stage P15
has OBO namespace: FlyBase_development_CV
id: FBdv:00005366
comment: Temporal ordering number - 740.

Axiom
annotated source: pharate adult stage P15
annotated property: definition
annotated target: Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

pharate adult stage P15(i)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage P15
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P14
definition: Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).
has exact synonym: meconium stage
has exact synonym: pupal stage P15(i)
has OBO namespace: FlyBase_development_CV
id: FBdv:00005367
comment: Temporal ordering number - 750.

Axiom
annotated source: pharate adult stage P15(i)
annotated property: definition
annotated target: Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P15(i)
annotated property: hasExactSynonym
annotated target: meconium stage
database_cross_reference: FlyBase:FBrf0036849

pharate adult stage P15(ii)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: pharate adult stage P15
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P15(i)
definition: Stage which starts when the operculum opens and ends when eclosion is completed. Duration at 25 degrees C: approximately 24 minutes. (219.6-220 hours after egg laying; 99.6-100 hours after puparium formation).
has exact synonym: eclosion stage
has exact synonym: pupal stage P15(ii)
has OBO namespace: FlyBase_development_CV
id: FBdv:00005368
comment: Temporal ordering number - 760.

Axiom
annotated source: pharate adult stage P15(ii)
annotated property: definition
annotated target: Stage which starts when the operculum opens and ends when eclosion is completed. Duration at 25 degrees C: approximately 24 minutes. (219.6-220 hours after egg laying; 99.6-100 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355

Axiom
annotated source: pharate adult stage P15(ii)
annotated property: hasExactSynonym
annotated target: eclosion stage
database_cross_reference: FlyBase:FBrf0036849

adult stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P15
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P15(ii)
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: P-stage
definition: The stage of the Drosophila life-cycle from eclosion to death.
has OBO namespace: FlyBase_development_CV
id: FBdv:00005369
comment: Temporal ordering number - 770.

Axiom
annotated source: adult stage
annotated property: definition
annotated target: The stage of the Drosophila life-cycle from eclosion to death.
database_cross_reference: FBC:DOS

adult stage A1
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: immature adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P15(ii)
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: P-stage
subclass of: Restriction
  on property: immediately precedes
  some values from: adult stage A2
definition: Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.
has alternative id: FBdv:00005373
has OBO namespace: FlyBase_development_CV
has related synonym: adult stage I
id: FBdv:00005370
comment: Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours.

Axiom
annotated source: adult stage A1
annotated property: definition
annotated target: Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.
database_cross_reference: FlyBase:FBrf0049147

adult stage A2
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: immature adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: adult stage A1
subclass of: Restriction
  on property: immediately precedes
  some values from: adult stage A3
definition: Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.
has alternative id: FBdv:00005374
has OBO namespace: FlyBase_development_CV
has related synonym: adult stage II
id: FBdv:00005371
comment: Temporal ordering number - 790.

Axiom
annotated source: adult stage A2
annotated property: definition
annotated target: Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.
database_cross_reference: FlyBase:FBrf0049147

pharate adult stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: substage of
  some values from: P-stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pupal stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pupal stage P7
subclass of: Restriction
  on property: immediately precedes
  some values from: adult stage
subclass of: Restriction
  on property: immediately precedes
  some values from: adult stage A1
subclass of: Restriction
  on property: immediately precedes
  some values from: immature adult stage
definition: The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).
has OBO namespace: FlyBase_development_CV
id: FBdv:00006011
comment: Temporal ordering number - 625.

Axiom
annotated source: pharate adult stage
annotated property: definition
annotated target: The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).
database_cross_reference: FlyBase:FBrf0036849
database_cross_reference: FlyBase:FBrf0048355
database_cross_reference: FlyBase:FBrf0049147

adult stage A3
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: immature adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: adult stage A2
subclass of: Restriction
  on property: immediately precedes
  some values from: mature adult stage
definition: Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.
has alternative id: FBdv:00005375
has OBO namespace: FlyBase_development_CV
has related synonym: adult stage III
id: FBdv:00006012
comment: Temporal ordering number - 800.

Axiom
annotated source: adult stage A3
annotated property: definition
annotated target: Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.
database_cross_reference: FlyBase:FBrf0049147

P-stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar larval stage L2
subclass of: Restriction
  on property: immediately preceded by
  some values from: late third instar larval stage
subclass of: Restriction
  on property: immediately precedes
  some values from: adult stage
subclass of: Restriction
  on property: immediately precedes
  some values from: adult stage A1
subclass of: Restriction
  on property: immediately precedes
  some values from: immature adult stage
definition: The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2008-06-05T04:51:40Z
has broad synonym: metamorphosis
has OBO namespace: FlyBase_development_CV
has related synonym: pupal stage
id: FBdv:00007001
comment: Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage.

Axiom
annotated source: P-stage
annotated property: definition
annotated target: The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.
database_cross_reference: FBC:DOS

third instar larval stage L1
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: late third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: wandering third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar - cleared gut stage
definition: Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.
has OBO namespace: FlyBase_development_CV
id: FBdv:00007004
comment: Temporal ordering number - 470.

Axiom
annotated source: third instar larval stage L1
annotated property: definition
annotated target: Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.
database_cross_reference: FlyBase:FBrf0036849

third instar larval stage L2
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: late third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar larval stage L1
definition: The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.
has exact synonym: spiracles everted larva
has OBO namespace: FlyBase_development_CV
has related synonym: white prepupa
id: FBdv:00007005
comment: Temporal ordering number - 480.

Axiom
annotated source: third instar larval stage L2
annotated property: definition
annotated target: The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.
database_cross_reference: FlyBase:FBrf0036849

Axiom
annotated source: third instar larval stage L2
annotated property: hasExactSynonym
annotated target: spiracles everted larva
database_cross_reference: FlyBase:FBrf0036849

Axiom
annotated source: third instar larval stage L2
annotated property: hasRelatedSynonym
annotated target: white prepupa
database_cross_reference: FlyBase:FBrf0036849

late third instar larval stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: early third instar larval stage
definition: Third instar larva from the beginning of wandering to the beginning of puparium formation.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2008-12-11T01:19:53Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007007
comment: Temporal ordering number - 450.

Axiom
annotated source: late third instar larval stage
annotated property: definition
annotated target: Third instar larva from the beginning of wandering to the beginning of puparium formation.
database_cross_reference: FBC:DOS

developmental process
type: Class
subclass of: biological process
definition: A biological process whose specific outcome is the progression of an integrated living unit (an anatomical structure or an entire organism) over time from an initial condition to a later condition.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2009-10-01T05:56:42Z
database_cross_reference: GO:0032502
has OBO namespace: FlyBase_development_CV
id: FBdv:00007009

Axiom
annotated source: developmental process
annotated property: definition
annotated target: A biological process whose specific outcome is the progression of an integrated living unit (an anatomical structure or an entire organism) over time from an initial condition to a later condition.
database_cross_reference: GO:0032502

embryonic cycle
type: Class
subclass of: biological process
subclass of: GO_0045448
definition: A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2009-10-01T05:57:41Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007011

Axiom
annotated source: embryonic cycle
annotated property: definition
annotated target: A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.
database_cross_reference: FlyBase:FBrf0049535
database_cross_reference: FlyBase:FBrf0089570

life stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: Drosophila life
definition: A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2009-10-01T05:59:22Z
has exact synonym: life cycle stage
has OBO namespace: FlyBase_development_CV
id: FBdv:00007012

Axiom
annotated source: life stage
annotated property: definition
annotated target: A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.
database_cross_reference: FBC:DOS

age
type: Class
subclass of: BFO_0000003
definition: Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2010-09-29T12:25:36Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007013

Axiom
annotated source: age
annotated property: definition
annotated target: Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.
database_cross_reference: FBC:DOS

adult age in days
type: Class
subclass of: age
definition: Temporal subdivision of adulthood in days post-eclosion.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2010-09-29T12:28:05Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007014

Axiom
annotated source: adult age in days
annotated property: definition
annotated target: Temporal subdivision of adulthood in days post-eclosion.
database_cross_reference: FBC:DOS

embryonic stage 17(i)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 17
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 16
definition: The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).
contributor: http://orcid.org/0000-0002-7073-9172
date: 2011-04-26T11:57:15Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007015
comment: Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C.

Axiom
annotated source: embryonic stage 17(i)
annotated property: definition
annotated target: The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).
database_cross_reference: FBC:DOS

embryonic stage 17(ii)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 17
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 17(i)
definition: Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).
contributor: http://orcid.org/0000-0002-7073-9172
date: 2011-04-26T12:00:15Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007016
comment: Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C.

Axiom
annotated source: embryonic stage 17(ii)
annotated property: definition
annotated target: Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).
database_cross_reference: FBC:DOS

embryonic stage 17(iii)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 17
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 17(ii)
definition: Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).
contributor: http://orcid.org/0000-0002-7073-9172
date: 2011-04-26T12:01:18Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007017
comment: Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C.

Axiom
annotated source: embryonic stage 17(iii)
annotated property: definition
annotated target: Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).
database_cross_reference: FBC:DOS

embryonic stage 17(iv)
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: embryonic stage 17
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 17(iii)
definition: Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).
contributor: http://orcid.org/0000-0002-7073-9172
date: 2011-04-26T12:03:14Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007018
comment: Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C.

Axiom
annotated source: embryonic stage 17(iv)
annotated property: definition
annotated target: Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).
database_cross_reference: FBC:DOS

third instar - uncleared gut stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: wandering third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: early third instar larval stage
definition: The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.
has OBO namespace: FlyBase_development_CV
id: FBdv:00007019
comment: Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994).

Axiom
annotated source: third instar - uncleared gut stage
annotated property: definition
annotated target: The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.
database_cross_reference: FlyBase:FBrf0076598

third instar - partially cleared gut stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: wandering third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar - uncleared gut stage
definition: The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.
has OBO namespace: FlyBase_development_CV
id: FBdv:00007020
comment: Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994).

Axiom
annotated source: third instar - partially cleared gut stage
annotated property: definition
annotated target: The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.
database_cross_reference: FlyBase:FBrf0076598

third instar - cleared gut stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: wandering third instar larval stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: third instar - partially cleared gut stage
definition: The substage of the wandering third instar larval stage when the larva has cleared its gut contents.
has OBO namespace: FlyBase_development_CV
id: FBdv:00007021
comment: Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994.

Axiom
annotated source: third instar - cleared gut stage
annotated property: definition
annotated target: The substage of the wandering third instar larval stage when the larva has cleared its gut contents.
database_cross_reference: FlyBase:FBrf0076598

biological process
type: Class
subclass of: BFO_0000003
definition: The execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module.
database_cross_reference: GO:0008150
has OBO namespace: FlyBase_development_CV
id: FBdv:00007024

Axiom
annotated source: biological process
annotated property: definition
annotated target: The execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module.
database_cross_reference: GO:0008150

immature adult stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: substage of
  some values from: day 0 of adulthood
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: P-stage
subclass of: Restriction
  on property: immediately precedes
  some values from: mature adult stage
definition: The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).
contributor: http://orcid.org/0000-0002-7073-9172
date: 2013-01-08T20:06:59Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007025
comment: Temporal ordering number - 782.

Axiom
annotated source: immature adult stage
annotated property: definition
annotated target: The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).
database_cross_reference: FBC:DOS

mature adult stage
type: Class
subclass of: life stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: adult stage A3
subclass of: Restriction
  on property: immediately preceded by
  some values from: immature adult stage
definition: Life stage from the end of adult stage A3, when tanning is complete, to death.
contributor: http://orcid.org/0000-0002-7073-9172
date: 2013-01-10T13:03:54Z
has OBO namespace: FlyBase_development_CV
id: FBdv:00007026

Axiom
annotated source: mature adult stage
annotated property: definition
annotated target: Life stage from the end of adult stage A3, when tanning is complete, to death.
database_cross_reference: FBC:DOS

day 0 of adulthood
type: Class
subclass of: adult age in days
subclass of: Restriction
  on property: substage of
  some values from: adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P15
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage P15(ii)
subclass of: Restriction
  on property: immediately preceded by
  some values from: pharate adult stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: P-stage
definition: The day of eclosion.
has OBO namespace: FlyBase_development_CV
id: FBdv:00007075
comment: Temporal ordering number - 780.

Axiom
annotated source: day 0 of adulthood
annotated property: definition
annotated target: The day of eclosion.
database_cross_reference: FBC:DOS

early extended germ band stage
type: Class
subclass of: developmental stage
subclass of: Restriction
  on property: substage of
  some values from: extended germ band stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: gastrula stage
subclass of: Restriction
  on property: immediately preceded by
  some values from: embryonic stage 8
definition: A collective term for stages 9 and 10.
has OBO namespace: FlyBase_development_CV
id: FBdv:00014201
comment: Temporal ordering number - 270.

Axiom
annotated source: early extended germ band stage
annotated property: definition
annotated target: A collective term for stages 9 and 10.
database_cross_reference: FBC:DOS

Drosophila melanogaster
type: Class
subclass of: invertebrate
IAO_0000111: Drosophila melanogaster
IAO_0000118: Sophophora melanogaster
IAO_0000118: fruit fly
IAO_0000412: ncbitaxon.owl

planned process
type: Class
equivalent class: Restriction
  on property: realizes
  some values from: Restriction
    on property: concretizes
    some values from: IAO_0000104
subclass of: BFO_0000015
IAO_0000111: planned process
IAO_0000112: Injecting mice with a vaccine in order to test its efficacy
IAO_0000114: IAO_0000122
definition: A process that realizes a plan which is the concretization of a plan specification.
IAO_0000116: 'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)
IAO_0000116: We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some objectives is a planned process.
IAO_0000117: Bjoern Peters
IAO_0000119: branch derived
IAO_0000232: 6/11/9: Edited at workshop. Used to include: is initiated by an agent
IAO_0000232: This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)

specimen role
type: Class
subclass of: BFO_0000023
subclass of: Restriction
  on property: characteristic of
  some values from: Class
    intersection of: BFO_0000040
    intersection of: Restriction
      on property: is specified output of
      some values from: specimen collection process
IAO_0000111: specimen role
IAO_0000112: liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient.
IAO_0000114: IAO_0000122
definition: A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen.
IAO_0000116: 22Jun09. The definition includes whole organisms, and can include a human. The link between specimen role and study subject role has been removed. A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role.
IAO_0000116: Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.
IAO_0000116: blood taken from animal: animal continues in study, whereas blood has role specimen. something taken from study subject, leaves the study and becomes the specimen.
IAO_0000116: parasite example - when parasite in people we study people, people are subjects and parasites are specimen - when parasite extracted, they become subject in the following study specimen can later be subject.
IAO_0000117: GROUP: Role Branch
IAO_0000119: OBI
IAO_0000233: https://github.com/obi-ontology/obi/issues/1013

specimen collection process
type: Class
equivalent class: Class
  intersection of: planned process
  intersection of: Restriction
    on property: achieves_planned_objective
    some values from: specimen collection objective
subclass of: planned process
subclass of: Restriction
  on property: has specified input
  some values from: BFO_0000040
subclass of: Restriction
  on property: has specified output
  some values from: specimen
IAO_0000111: specimen collection process
IAO_0000112: drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation, collecting a stone from a site
IAO_0000114: IAO_0000122
definition: A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed.
IAO_0000116: Definition updated following discussion on 2024-10-07 OBI dev call.
IAO_0000116: Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation.
IAO_0000116: Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role.
IAO_0000116: Philly2013: The specimen_role for the specimen is created during the specimen collection process.
IAO_0000116: label changed to 'specimen collection process' on 10/27/2014, details see tracker: http://sourceforge.net/p/obi/obi-terms/716/
IAO_0000117: Bjoern Peters
IAO_0000118: specimen collection
IAO_0000232: 5/31/2012: This process is not necessarily an acquisition, as specimens may be collected from materials already in posession
IAO_0000232: 6/9/09: used at workshop

specimen collection objective
type: Class
subclass of: IAO_0000005
IAO_0000111: specimen collection objective
IAO_0000112: The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient.
IAO_0000114: IAO_0000122
definition: A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed.
IAO_0000116: OBI recommends against subclassing this term in order to avoid further parallel hierarchies between this term and specimen collection process.
IAO_0000117: Bjoern Peters
IAO_0000119: Bjoern Peters

specimen from organism
type: Class
equivalent class: Class
  intersection of: specimen
  intersection of: Restriction
    on property: is specified output of
    some values from: Class
      intersection of: specimen collection process
      intersection of: Restriction
        on property: has specified input
        some values from: Class
subclass of: specimen
IAO_0000111: specimen from organism
IAO_0000114: IAO_0000122
definition: A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm).
IAO_0000117: PERSON: Chris Stoeckert, Jie Zheng
IAO_0000118: tissue specimen
IAO_0000119: MO_954 organism_part

collection of specimens
type: Class
equivalent class: Class
  intersection of: BFO_0000040
  intersection of: Restriction
    on property: has member
    all values from: specimen
subclass of: BFO_0000040
IAO_0000111: collection of specimens
IAO_0000112: Blood cells collected from multiple donors over the course of a study.
IAO_0000114: IAO_0000125
definition: A material entity that has two or more specimens as its parts.
IAO_0000116: Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/
IAO_0000117: Person: Chris Stoeckert, Jie Zheng
IAO_0000119: OBIB, OBI

organism
type: Class
equivalent class: Class
  union of: NCBITaxon_10239
  union of: NCBITaxon 2
  union of: NCBITaxon 2157
  union of: NCBITaxon 2759
subclass of: BFO_0000040
IAO_0000111: organism
IAO_0000112: animal
IAO_0000112: fungus
IAO_0000112: plant
IAO_0000112: virus
IAO_0000114: IAO_0000122
definition: A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.
IAO_0000116: 10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')
IAO_0000116: 13-02-2009: OBI doesn't take position as to when an organism starts or ends being an organism - e.g. sperm, foetus. This issue is outside the scope of OBI.
IAO_0000117: GROUP: OBI Biomaterial Branch
IAO_0000119: WEB: http://en.wikipedia.org/wiki/Organism

specimen
type: Class
equivalent class: Class
  intersection of: BFO_0000040
  intersection of: Restriction
    on property: has role
    some values from: specimen role
subclass of: BFO_0000040
IAO_0000111: specimen
IAO_0000112: Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen; collecting a stone from a site.
IAO_0000114: IAO_0000122
definition: A material entity that is collected for potential use as an input upon which measurements or observations are performed.
IAO_0000117: PERSON: James Malone
IAO_0000117: PERSON: Philippe Rocca-Serra
IAO_0000119: GROUP: OBI Biomaterial Branch
IAO_0000233: https://github.com/obi-ontology/obi/issues/1013

morphology
type: Class
subclass of: quality
definition: A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure.
IAO_0000412: pato.owl
has OBO namespace: quality
id: PATO:0000051
in subset: attribute slim

structure
type: Class
subclass of: morphology
definition: A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form.
IAO_0000412: pato.owl
has alternative id: PATO:0001452
has broad synonym: conformation
has exact synonym: relational structural quality
has OBO namespace: quality
id: PATO:0000141
in subset: attribute slim

fasciculated
type: Class
subclass of: structure
definition: A structural quality inhering in a bearer by virtue of the bearer's forming a bundle of aligned anatomical fibers, as of muscle or nerve.
IAO_0000412: pato.owl
RO_0002604: PATO_0001959
has exact synonym: fascicled
has OBO namespace: quality
id: PATO:0001861
in subset: mpath slim
in subset: value slim

system
type: Class
subclass of: BFO_0000040
definition: A material entity consisting of multiple components that are causally integrated.
IAO_0000116: May be replaced by a BFO class, as discussed in http://www.jbiomedsem.com/content/4/1/43
IAO_0000117: https://orcid.org/0000-0002-6601-2165
IAO_0000119: http://www.jbiomedsem.com/content/4/1/43

anatomical structure
type: Class
subclass of: anatomical entity
definition: Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome.
IAO_0000412: uberon.owl
RO_0002175: NCBITaxon_33090
RO_0002175: NCBITaxon_33208
RO_0002175: NCBITaxon 4751
database_cross_reference: AAO:0010825
database_cross_reference: AEO:0000003
database_cross_reference: BILA:0000003
database_cross_reference: CARO:0000003
database_cross_reference: EHDAA2:0003003
database_cross_reference: EMAPA:0
database_cross_reference: FBbt:00007001
database_cross_reference: FMA:305751
database_cross_reference: FMA:67135
database_cross_reference: GAID:781
database_cross_reference: HAO:0000003
database_cross_reference: MA:0003000
database_cross_reference: MESH:D000825
database_cross_reference: SCTID:362889002
database_cross_reference: TAO:0000037
database_cross_reference: TGMA:0001823
database_cross_reference: VHOG:0001759
database_cross_reference: XAO:0003000
database_cross_reference: ZFA:0000037
database_cross_reference: http://dbpedia.org/ontology/AnatomicalStructure
has exact synonym: biological structure
has exact synonym: connected biological structure
has OBO namespace: uberon
id: UBERON:0000061
in subset: common anatomy
in subset: human subset
in subset: mouse subset
in subset: upper level

anatomical entity
type: Class
equivalent class: Restriction
  on property: is anatomical entity
  has self: true
subclass of: assay biology component
definition: Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
IAO_0000412: uberon.owl
RO_0002175: NCBITaxon_33090
RO_0002175: NCBITaxon_33208
RO_0002175: NCBITaxon 4751
database_cross_reference: AAO:0010841
database_cross_reference: AEO:0000000
database_cross_reference: BFO:0000004
database_cross_reference: BILA:0000000
database_cross_reference: BIRNLEX:6
database_cross_reference: CARO:0000000
database_cross_reference: EHDAA2:0002229
database_cross_reference: FBbt:10000000
database_cross_reference: FMA:62955
database_cross_reference: HAO:0000000
database_cross_reference: MA:0000001
database_cross_reference: NCIT:C12219
database_cross_reference: TAO:0100000
database_cross_reference: TGMA:0001822
database_cross_reference: UMLS:C1515976
database_cross_reference: WBbt:0000100
database_cross_reference: XAO:0000000
database_cross_reference: ZFA:0100000
has OBO namespace: uberon
id: UBERON:0001062
in subset: common anatomy
in subset: human subset
in subset: mouse subset
in subset: upper level

eukaryote
type: Class
subclass of: cellular organisms
definition: This includes fungi, vertebrates and invertebrates. Eukaryotic cells have a well-defined nucleus and membrane enveloped organelles namely, mitochondria, endoplasmic reticulum, golgi apparatus, and lysosomes.

invertebrate
type: Class
subclass of: metazoa
definition: These animals lack a vertebral column and many of which are used as model organisms in HTS screening including Drosophila, C.elegans, sea urchin, etc.

organism
type: Class
subclass of: assay biology component
definition: The organism related to the target / meta-target of the bioassay. It includes both bacterium and eukaryote.

cellular organisms
type: Class
subclass of: organism
definition: This includes all organisms which are made up of cells, e.g. bacteria, plants and animals.

metazoa
type: Class
subclass of: eukaryote
definition: Metazoa comprises of animals, which are multicellular eukaryotic organisms. This includes those having a vertebral column (e.g. fish, frog, snake, bird, human) and those that do not (e.g. worm, fly, star fish, etc).

quality
type: Class

assay biology component
type: Class

scRNAseq_2020_Kurmangaliyev
type: NamedIndividual
type: project
type: Restriction
  on property: is specified output of
  some values from: single-cell RNA-Seq
filtered gene count: 5975
total gene count: 16172
node label: DataSet
definition: Single-cell RNA-seq study of the pupal optic lobe
licence: VFBlicense CC BY 4 0
references: FBrf0247594
database_cross_reference: scExpressionAtlas

Axiom
annotated source: scRNAseq_2020_Kurmangaliyev
annotated property: database_cross_reference
annotated target: scExpressionAtlas
accession: E-GEOD-156455

scRNAseq_2020_Kurmangaliyev_W1118
type: NamedIndividual
type: biosample
type: Restriction
  on property: part of
  some values from: female organism
type: Restriction
  on property: overlaps
  some values from: adult optic lobe
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
input of: scRNAseq_2020_Kurmangaliyev_W1118_seq
node label: Sample
definition: Dissociated cells from pupal optic lobes of w1118 flies
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_W1118_seq
type: NamedIndividual
type: assay
type: Restriction
  on property: has assay method
  some values from: 10x sequencing
has input: scRNAseq_2020_Kurmangaliyev_W1118
node label: Assay
definition: Single-cell RNA-seq of dissociated cells from pupal optic lobes of w1118 flies
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_DGRP
type: NamedIndividual
type: biosample
type: Restriction
  on property: part of
  some values from: female organism
type: Restriction
  on property: overlaps
  some values from: adult optic lobe
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
input of: scRNAseq_2020_Kurmangaliyev_DGRP_seq
node label: Sample
definition: Dissociated cells from pupal optic lobes of DGRP flies
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_DGRP_seq
type: NamedIndividual
type: assay
type: Restriction
  on property: has assay method
  some values from: 10x sequencing
has input: scRNAseq_2020_Kurmangaliyev_DGRP
node label: Assay
definition: Single-cell RNA-seq of dissociated cells from pupal optic lobes of DGRP flies
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
type: NamedIndividual
type: cell clustering analysis
has part: scRNAseq_2020_Kurmangaliyev_W1118
has part: scRNAseq_2020_Kurmangaliyev_W1118_seq
has part: scRNAseq_2020_Kurmangaliyev_DGRP
has part: scRNAseq_2020_Kurmangaliyev_DGRP_seq
definition: Consolidated clustering analysis of cells from the pupal optic lobe
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_optic_lobe_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: adult optic lobe neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 66040
filtered gene count: 3277
total gene count: 15742
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, optic lobe neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T3_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T3 neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2294
filtered gene count: 2462
total gene count: 11714
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T3 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_TmY5a_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary Y neuron TmY5a
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2902
filtered gene count: 2977
total gene count: 12036
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, TmY5a neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T2a_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T2a neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2011
filtered gene count: 2804
total gene count: 11678
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T2a neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm1
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2222
filtered gene count: 3199
total gene count: 11909
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_optic_lobe_glial_cells
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: adult optic lobe glial cell
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 15575
filtered gene count: 2738
total gene count: 14261
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, optic lobe glial cells cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm5c_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm5c
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1397
filtered gene count: 2895
total gene count: 11259
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm5c neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_L2_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lamina monopolar neuron L2
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2621
filtered gene count: 3959
total gene count: 12187
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, L2 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm3_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm3
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 5746
filtered gene count: 2489
total gene count: 12760
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm3 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T5b_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T5b neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2293
filtered gene count: 2623
total gene count: 11801
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T5b neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T4b_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T4b neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2175
filtered gene count: 2575
total gene count: 11592
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T4b neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_TmY3_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary Y neuron TmY3
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1799
filtered gene count: 3167
total gene count: 11657
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, TmY3 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Mi9_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: medulla intrinsic neuron Mi9
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 3062
filtered gene count: 2740
total gene count: 12013
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Mi9 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm2_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm2
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2862
filtered gene count: 2441
total gene count: 11919
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm2 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm2_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm2
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2600
filtered gene count: 3156
total gene count: 11877
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm2 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm4_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm4
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2592
filtered gene count: 2913
total gene count: 12029
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm4 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_L1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lamina monopolar neuron L1
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2356
filtered gene count: 3738
total gene count: 11940
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, L1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_lamina_intrinsic_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lamina intrinsic neuron Lai
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 549
filtered gene count: 3961
total gene count: 10471
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, lamina intrinsic neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm9a_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm9a
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1764
filtered gene count: 2621
total gene count: 11432
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm9a neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_outer_photoreceptor_cells
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: outer photoreceptor cell
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2619
filtered gene count: 3980
total gene count: 12343
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, outer photoreceptor cells cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T2_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T2 neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2680
filtered gene count: 2940
total gene count: 12017
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T2 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T5d_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T5d neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2104
filtered gene count: 2549
total gene count: 11668
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T5d neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Mi4_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: medulla intrinsic neuron Mi4
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2830
filtered gene count: 2994
total gene count: 12123
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Mi4 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Mi15_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: medulla intrinsic neuron Mi15
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2226
filtered gene count: 2401
total gene count: 11670
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Mi15 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm10_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm10
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1480
filtered gene count: 3323
total gene count: 11417
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm10 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_L4_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lamina monopolar neuron L4
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1799
filtered gene count: 2734
total gene count: 11511
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, L4 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_L3_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lamina monopolar neuron L3
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1809
filtered gene count: 3248
total gene count: 11675
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, L3 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LLPC1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula-lobula plate columnar neuron LLPC1
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 708
filtered gene count: 3450
total gene count: 10887
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LLPC1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm8_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm8a
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1790
filtered gene count: 2731
total gene count: 11499
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm8 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T4c_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T4c neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1723
filtered gene count: 2528
total gene count: 11372
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T4c neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_C2_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: centrifugal neuron C2
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2598
filtered gene count: 2767
total gene count: 11802
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, C2 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm29_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm29
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1082
filtered gene count: 2843
total gene count: 10936
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm29 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm11_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm11
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 364
filtered gene count: 3490
total gene count: 9859
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm11 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm3_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm3
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 3337
filtered gene count: 2767
total gene count: 12241
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm3 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm20_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm20
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2835
filtered gene count: 2577
total gene count: 12004
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm20 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LC10b_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula columnar neuron LC10b
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 221
filtered gene count: 3417
total gene count: 9596
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LC10b neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Mi1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: medulla intrinsic neuron Mi1
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2269
filtered gene count: 3329
total gene count: 11929
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Mi1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LC6_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula columnar neuron LC6
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 304
filtered gene count: 3869
total gene count: 10133
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LC6 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T5a_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T5a neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2171
filtered gene count: 2645
total gene count: 11706
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T5a neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_inner_photoreceptor_cells
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: inner photoreceptor cell
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1212
filtered gene count: 4184
total gene count: 11846
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, inner photoreceptor cells cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T5c_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T5c neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2405
filtered gene count: 2523
total gene count: 11959
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T5c neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LPi3-4_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula plate intrinsic neuron LPi3-4
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 348
filtered gene count: 3983
total gene count: 9972
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LPi3-4 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T4d_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T4d neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2728
filtered gene count: 2474
total gene count: 11900
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T4d neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LPLC1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula plate-lobula columnar neuron LPLC1
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 107
filtered gene count: 4298
total gene count: 8949
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LPLC1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LC10a_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula columnar neuron LC10a
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 575
filtered gene count: 3265
total gene count: 10719
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LC10a neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Tm9b_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: transmedullary neuron Tm9b
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1139
filtered gene count: 2553
total gene count: 10864
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Tm9b neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T4a_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: T4a neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2673
filtered gene count: 2659
total gene count: 11975
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T4a neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_L5_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lamina monopolar neuron L5
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2263
filtered gene count: 3148
total gene count: 11725
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, L5 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm12_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm12
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 571
filtered gene count: 3947
total gene count: 10428
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm12 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_C3_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: centrifugal neuron C3
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 2788
filtered gene count: 2944
total gene count: 11947
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, C3 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LC4_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula columnar neuron LC4
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 177
filtered gene count: 4315
total gene count: 9549
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LC4 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_lamina_wide-field_1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lamina wide-field 1 neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 648
filtered gene count: 4034
total gene count: 10619
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, lamina wide-field 1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_T1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: columnar neuron T1
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 1762
filtered gene count: 3528
total gene count: 11532
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, T1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm4_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm4
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 119
filtered gene count: 3912
total gene count: 8903
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm4 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Pm3_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: proximal medullary amacrine neuron Pm3
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 424
filtered gene count: 3919
total gene count: 10220
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Pm3 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_lamina_wide-field_2_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lamina wide-field 2 neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 639
filtered gene count: 4277
total gene count: 10618
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, lamina wide-field 2 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm9_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm9
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 377
filtered gene count: 4330
total gene count: 10165
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm9 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LPLC2_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula plate-lobula columnar neuron LPLC2
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 160
filtered gene count: 4197
total gene count: 9256
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LPLC2 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Dm1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: distal medullary amacrine neuron Dm1
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 124
filtered gene count: 4356
total gene count: 8963
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Dm1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_Pm4_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: proximal medullary amacrine neuron Pm4
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 326
filtered gene count: 4527
total gene count: 9935
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, Pm4 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_LPC1_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: lobula plate columnar neuron LPC1
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 117
filtered gene count: 3341
total gene count: 8749
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, LPC1 neurons cluster
source: scRNAseq_2020_Kurmangaliyev

scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering_photoreceptor_neurons
type: NamedIndividual
type: transcriptional cell cluster
type: Restriction
  on property: composed primarily of
  some values from: photoreceptor neuron
type: Restriction
  on property: existence overlaps
  some values from: pupal stage
part of: scRNAseq_2020_Kurmangaliyev_MAIN_seq_clustering
cell count: 126
filtered gene count: 3455
total gene count: 8935
node label: Cluster
definition: Consolidated clustering analysis of cells from the pupal optic lobe, photoreceptor neurons cluster
source: scRNAseq_2020_Kurmangaliyev

FBrf0247594
type: NamedIndividual
node label: pub